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Wyszukujesz frazę ""Khan, Mohammad Faheem"" wg kryterium: Autor


Wyświetlanie 1-4 z 4
Tytuł:
Novel Imbricatolic acid derivatives as protein tyrosine phosphatase-1B inhibitors: Design, synthesis, biological evaluation and molecular docking.
Autorzy:
Khan MF; Department of Chemistry, University of Lucknow, Lucknow 226007, Uttar Pradesh, India.
Azad CS; 'Hygeia', Center of Excellences in Pharmaceutical Sciences (CEPS), Guru Govind Singh Indraprastha University, Sec 16-C, Dwarka, New Delhi 110078, India.
Kumar A; Department of Chemistry, University of Lucknow, Lucknow 226007, Uttar Pradesh, India.
Saini M; Department of Chemistry, University of Lucknow, Lucknow 226007, Uttar Pradesh, India.
Narula AK; 'Hygeia', Center of Excellences in Pharmaceutical Sciences (CEPS), Guru Govind Singh Indraprastha University, Sec 16-C, Dwarka, New Delhi 110078, India.
Jain S; Department of Chemistry, University of Lucknow, Lucknow 226007, Uttar Pradesh, India. Electronic address: .
Źródło:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2016 Apr 15; Vol. 26 (8), pp. 1988-92. Date of Electronic Publication: 2016 Mar 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Drug Design*
Molecular Docking Simulation*
Diterpenes/*pharmacology
Enzyme Inhibitors/*chemical synthesis
Enzyme Inhibitors/*pharmacology
Protein Tyrosine Phosphatase, Non-Receptor Type 1/*antagonists & inhibitors
Cell Line ; Diterpenes/chemical synthesis ; Diterpenes/chemistry ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/chemistry ; Humans ; Molecular Structure ; Protein Tyrosine Phosphatase, Non-Receptor Type 1/metabolism ; Recombinant Proteins/metabolism ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Design and synthesis of lupeol analogues and their glucose uptake stimulatory effect in L6 skeletal muscle cells.
Autorzy:
Khan MF; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Maurya CK; Biochemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Dev K; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research, New Delhi 110001, India.
Arha D; Biochemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research, New Delhi 110001, India.
Rai AK; Biochemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Tamrakar AK; Biochemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research, New Delhi 110001, India.
Maurya R; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research, New Delhi 110001, India. Electronic address: .
Źródło:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2014 Jun 15; Vol. 24 (12), pp. 2674-9. Date of Electronic Publication: 2014 Apr 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Drug Design*
Hypoglycemic Agents/*chemical synthesis
Hypoglycemic Agents/*pharmacology
Muscle, Skeletal/*drug effects
Pentacyclic Triterpenes/*chemical synthesis
Pentacyclic Triterpenes/*pharmacology
Biological Transport ; Carbohydrate Metabolism/genetics ; Cells, Cultured ; Dose-Response Relationship, Drug ; Glucose/metabolism ; Humans ; Hypoglycemic Agents/chemistry ; Molecular Structure ; Pentacyclic Triterpenes/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Synthesis of novel imbricatolic acid analogues via insertion of N-substituted piperazine at C-15/C-19 positions, displaying glucose uptake stimulation in L6 skeletal muscle cells.
Autorzy:
Khan MF; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, CSIR, Lucknow 226001, India.
Kumar P
Pandey J
Srivastava AK
Tamrakar AK
Maurya R
Źródło:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2012 Jul 15; Vol. 22 (14), pp. 4636-9. Date of Electronic Publication: 2012 Jun 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diterpenes/*chemistry
Glucose/*metabolism
Muscle Cells/*drug effects
Muscle, Skeletal/*drug effects
Piperazines/*chemistry
Animals ; Cell Line ; Diterpenes/pharmacology ; Molecular Structure ; Muscle Cells/metabolism ; Muscle, Skeletal/metabolism ; Piperazine ; Rats ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Aza-annulation on the 16-dehydropregnenolone, via tandem intermolecular aldol process and intramolecular Michael addition.
Autorzy:
Kumar M; Medicinal and Process Chemistry Division, Central Drug Research Institute, CSIR, Lucknow 226 001, India.
Rawat P
Khan MF
Rawat AK
Srivastava AK
Maurya R
Źródło:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2011 Apr 15; Vol. 21 (8), pp. 2232-7. Date of Electronic Publication: 2011 Mar 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aldehydes/*chemistry
Aza Compounds/*chemistry
Dipeptidyl Peptidase 4/*chemistry
Dipeptidyl-Peptidase IV Inhibitors/*chemistry
Pregnenolone/*analogs & derivatives
Amines/chemistry ; Cyclization ; Dipeptidyl Peptidase 4/metabolism ; Dipeptidyl-Peptidase IV Inhibitors/chemical synthesis ; Dipeptidyl-Peptidase IV Inhibitors/pharmacology ; Pregnenolone/chemical synthesis ; Pregnenolone/chemistry ; Pregnenolone/pharmacology
Czasopismo naukowe
    Wyświetlanie 1-4 z 4

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