Autor: "Khokha R" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: TIMP3 controls cell fate to confer hepatocellular carcinoma resistance.
Autorzy:: Defamie V; Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada.
Sanchez O; University of Ontario Institute of Technology, Oshawa, Ontario, Canada.
Murthy A; Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada.
Khokha R; Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada.; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2015 Jul 30; Vol. 34 (31), pp. 4098-108. Date of Electronic Publication: 2014 Oct 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carcinoma, Hepatocellular/*genetics
Disease Resistance/*genetics
Liver Neoplasms/*genetics
Tissue Inhibitor of Metalloproteinase-3/*physiology
Animals ; Apoptosis/genetics ; Carcinoma, Hepatocellular/pathology ; Carcinoma, Hepatocellular/prevention & control ; Cell Transformation, Neoplastic/genetics ; Cells, Cultured ; Cellular Senescence/genetics ; Cytoprotection/genetics ; Embryo, Mammalian ; Liver Neoplasms/pathology ; Liver Neoplasms/prevention & control ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout

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Skocz do pozycji: 2.

Tytuł:: Timp3 deficient mice show resistance to developing breast cancer.
Autorzy:: Jackson HW; Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada.
Hojilla CV; Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada.
Weiss A; Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada.
Sanchez OH; Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada.
Wood GA; Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada.
Khokha R; Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2015 Mar 25; Vol. 10 (3), pp. e0120107. Date of Electronic Publication: 2015 Mar 25 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Breast Neoplasms/*genetics
Breast Neoplasms/*pathology
Cell Transformation, Neoplastic/*genetics
Tissue Inhibitor of Metalloproteinase-3/*deficiency
Tissue Inhibitor of Metalloproteinase-3/*genetics
Animals ; Cell Transformation, Neoplastic/pathology ; Female ; Male ; Mammary Glands, Animal/pathology ; Mammary Neoplasms, Experimental/genetics ; Mammary Neoplasms, Experimental/pathology ; Mice ; Mice, Inbred C57BL ; Signal Transduction/genetics ; Tumor Necrosis Factor-alpha/genetics

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Skocz do pozycji: 3.

Tytuł:: Expansion of stem cells counteracts age-related mammary regression in compound Timp1/Timp3 null mice.
Autorzy:: Jackson HW; 1] Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 2M9, Canada [2] Princess Margaret Cancer Centre/University Health Network, Toronto, Ontario M5G 2M9, Canada.
Waterhouse P; Princess Margaret Cancer Centre/University Health Network, Toronto, Ontario M5G 2M9, Canada.
Sinha A; 1] Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 2M9, Canada [2] Princess Margaret Cancer Centre/University Health Network, Toronto, Ontario M5G 2M9, Canada.
Kislinger T; 1] Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 2M9, Canada [2] Princess Margaret Cancer Centre/University Health Network, Toronto, Ontario M5G 2M9, Canada.
Berman HK; 1] Princess Margaret Cancer Centre/University Health Network, Toronto, Ontario M5G 2M9, Canada [2] Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
Khokha R; 1] Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 2M9, Canada [2] Princess Margaret Cancer Centre/University Health Network, Toronto, Ontario M5G 2M9, Canada [3] Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.; Pokaż więcej
Źródło:: Nature cell biology [Nat Cell Biol] 2015 Mar; Vol. 17 (3), pp. 217-27. Date of Electronic Publication: 2015 Feb 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Aging/*genetics
Cell Proliferation/*genetics
Mammary Glands, Animal/*cytology
Stem Cells/*cytology
Tissue Inhibitor of Metalloproteinase-1/*genetics
Tissue Inhibitor of Metalloproteinase-3/*genetics
Age Factors ; Aging/metabolism ; Animals ; Cell Differentiation ; Cytoskeletal Proteins/genetics ; Cytoskeletal Proteins/metabolism ; Female ; Gene Expression Regulation, Developmental ; Mammary Glands, Animal/growth & development ; Mammary Glands, Animal/metabolism ; Mice ; Mice, Knockout ; Mitosis ; Receptors, Notch/genetics ; Receptors, Notch/metabolism ; Risk Factors ; Signal Transduction ; Spindle Apparatus/metabolism ; Spindle Apparatus/pathology ; Stem Cells/metabolism ; Tissue Inhibitor of Metalloproteinase-1/deficiency ; Tissue Inhibitor of Metalloproteinase-3/deficiency