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Tytuł:
Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings.
Autorzy:
Dapas M; Department of Human Genetics, University of Chicago, Chicago Illinois, United States of America.
Thompson EE; Department of Human Genetics, University of Chicago, Chicago Illinois, United States of America.
Wentworth-Sheilds W; Department of Human Genetics, University of Chicago, Chicago Illinois, United States of America.
Clay S; Department of Human Genetics, University of Chicago, Chicago Illinois, United States of America.
Visness CM; Rho Inc., Durham, North Carolina, United States of America.
Calatroni A; Rho Inc., Durham, North Carolina, United States of America.
Sordillo JE; Department of Population Medicine, Harvard Medical School, Boston, Massachusetts, United States of America.
Gold DR; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
Wood RA; Department of Pediatrics, Johns Hopkins University Medical Center, Baltimore, Maryland, United States of America.
Makhija M; Division of Allergy and Immunology, Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois, United States of America.
Khurana Hershey GK; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America.; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.
Sherenian MG; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America.; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.
Gruchalla RS; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
Gill MA; Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Liu AH; Department of Allergy and Immunology, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado, United States of America.
Kim H; Department of Medicine, Henry Ford Health System, Detroit, Michigan, United States of America.
Kattan M; Columbia University College of Physicians and Surgeons, New York, New York, United States of America.
Bacharier LB; Monroe Carell Jr. Children's Hospital at Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.
Rastogi D; Children's National Health System, Washington, District of Columbia, United States of America.
Altman MC; Department of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, United States of America.
Busse WW; Department of Pediatrics and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.
Becker PM; National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, United States of America.
Nicolae D; Department of Statistics, University of Chicago, Chicago, Illinois, United States of America.
O'Connor GT; Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts, United States of America.
Gern JE; Department of Pediatrics and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.
Jackson DJ; Department of Pediatrics and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.
Ober C; Department of Human Genetics, University of Chicago, Chicago Illinois, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2023 Jan 13; Vol. 19 (1), pp. e1010594. Date of Electronic Publication: 2023 Jan 13 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Lung*/metabolism
Genome-Wide Association Study*
Adult ; Adolescent ; Humans ; Child ; DNA Methylation/genetics ; Multiomics ; Forced Expiratory Volume/genetics ; Genotype ; Smoking
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans.
Autorzy:
Washington C 3rd; Department of Human Genetics, The University of Chicago, 928 E. 58th St. CLSC 507C, Chicago, IL, 60637, USA.
Dapas M; Department of Human Genetics, The University of Chicago, 928 E. 58th St. CLSC 507C, Chicago, IL, 60637, USA.
Biddanda A; Department of Human Genetics, The University of Chicago, 928 E. 58th St. CLSC 507C, Chicago, IL, 60637, USA.
Magnaye KM; Department of Human Genetics, The University of Chicago, 928 E. 58th St. CLSC 507C, Chicago, IL, 60637, USA.
Aneas I; Department of Human Genetics, The University of Chicago, 928 E. 58th St. CLSC 507C, Chicago, IL, 60637, USA.
Helling BA; Department of Human Genetics, The University of Chicago, 928 E. 58th St. CLSC 507C, Chicago, IL, 60637, USA.
Szczesny B; Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Boorgula MP; Department of Medicine, University of Colorado Denver, Aurora, CO, USA.
Taub MA; Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Kenny E; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Mathias RA; Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Barnes KC; Department of Medicine, University of Colorado Denver, Aurora, CO, USA.
Khurana Hershey GK; Division of Asthma Research, Cincinnati Children's Hospital, Cincinnati, OH, USA.
Kercsmar CM; Division of Asthma Research, Cincinnati Children's Hospital, Cincinnati, OH, USA.
Gereige JD; Department of Medicine, Division of Pulmonary, Allergy, Sleep, and Critical Care Medicine, Boston University School of Medicine, Boston, MA, USA.
Makhija M; Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
Gruchalla RS; University of Texas Southwestern Medical Center, Dallas, TX, USA.
Gill MA; University of Texas Southwestern Medical Center, Dallas, TX, USA.
Liu AH; Children's Hospital Colorado and University of Colorado School of Medicine, Aurora, CO, USA.
Rastogi D; Children's National Hospital and George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Busse W; University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Gergen PJ; NIH/NIAID, Bethesda, MD, USA.
Visness CM; Rho Federal Systems Division, Inc, Durham, NC, USA.
Gold DR; The Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Department of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.
Hartert T; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.
Johnson CC; Department of Public Health Sciences, Henry Ford Health Systems, Detroit, MI, USA.
Lemanske RF Jr; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Martinez FD; Asthma and Airway Disease Research Center, University of Arizona, Tucson, AZ, USA.
Miller RL; Department of Medicine, Division of Clinical Immunology Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Ownby D; Department of Public Health Sciences, Henry Ford Health Systems, Detroit, MI, USA.
Seroogy CM; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Wright AL; Asthma and Airway Disease Research Center, University of Arizona, Tucson, AZ, USA.
Zoratti EM; Department of Medicine, Henry Ford Health Systems, Detroit, MI, USA.
Bacharier LB; Department of Pediatrics, Monroe Carell Jr Children's Hospital at Vanderbilt University Medical Center, Nashville, TN, USA.
Kattan M; Department of Pediatrics, Columbia University Medical Center, New York, NY, USA.
O'Connor GT; Pulmonary Center, Boston University School of Medicine, Boston, MA, USA.
Wood RA; Department of Pediatrics, Johns Hopkins University, Baltimore, MD, USA.
Nobrega MA; Department of Human Genetics, The University of Chicago, 928 E. 58th St. CLSC 507C, Chicago, IL, 60637, USA.
Altman MC; Immunology Division, Benaroya Research Institute Systems, Seattle, WA, USA.; Department of Medicine, University of Washington, Seattle, WA, USA.
Jackson DJ; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Gern JE; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
McKennan CG; Department of Statistics, University of Pittsburgh, Pittsburgh, PA, USA.
Ober C; Department of Human Genetics, The University of Chicago, 928 E. 58th St. CLSC 507C, Chicago, IL, 60637, USA. .
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Corporate Authors:
CAAPA
Źródło:
Genome medicine [Genome Med] 2022 Sep 29; Vol. 14 (1), pp. 112. Date of Electronic Publication: 2022 Sep 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Black or African American*/genetics
Asthma*/genetics
Asthma*/metabolism
Alleles ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Humans ; Neoplasm Proteins/genetics ; Polymorphism, Single Nucleotide ; Pore Forming Cytotoxic Proteins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Heterogeneity of magnitude, allergen immunodominance, and cytokine polarization of cockroach allergen-specific T cell responses in allergic sensitized children.
Autorzy:
da Silva Antunes R; Division of Vaccine Discovery La Jolla Institute for Immunology La Jolla California USA.
Sutherland A; Division of Vaccine Discovery La Jolla Institute for Immunology La Jolla California USA.
Frazier A; Division of Vaccine Discovery La Jolla Institute for Immunology La Jolla California USA.
Schulten V; Division of Vaccine Discovery La Jolla Institute for Immunology La Jolla California USA.
Pomés A; Basic Research Indoor Biotechnologies, Inc. Charlottesville Virginia USA.
Glesner J; Basic Research Indoor Biotechnologies, Inc. Charlottesville Virginia USA.
Calatroni A; Rho Federal Systems Division Chapel Hill North Carolina USA.
Altman MC; Benaroya Research Institute Systems Immunology Division Department of Medicine University of Washington Seattle Washington USA.
Wood RA; Division of Pediatric Allergy, Immunology and Rheumatology Department of Pediatrics Johns Hopkins University School of Medicine Baltimore Maryland USA.
O'Connor GT; Boston University School of Medicine Pulmonary Center Boston Massachusetts USA.
Pongracic JA; Advanced General Pediatrics and Primary Care Ann & Robert H. Lurie Children's Hospital of Chicago Chicago Illinois USA.
Khurana Hershey GK; Division of Asthma Research Cincinnati Children's Hospital Cincinnati Ohio USA.
Kercsmar CM; Division of Pulmonary Medicine Cincinnati Children's Hospital Cincinnati Ohio USA.
Gruchalla RS; Divisions of Infectious Diseases and Pulmonary Vascular Biology Department of Pediatrics University of Texas Southwestern Medical Center Dallas Texas USA.
Gill M; Divisions of Infectious Diseases and Pulmonary Vascular Biology Department of Pediatrics University of Texas Southwestern Medical Center Dallas Texas USA.
Liu AH; Department of Pediatrics Children's Hospital Colorado University of Colorado School of Medicine Aurora Colorado USA.
Zoratti E; Henry Ford Health System and Wayne State University School of Medicine Detroit Michigan USA.
Kattan M; College of Physicians and Surgeons Columbia University New York New York USA.
Busse PJ; Division of Clinical Immunology and Allergy Icahn School of Medicine at Mount Sinai New York New York USA.
Bacharier LB; Department of Pediatrics Monroe Carell Jr Children's Hospital at Vanderbilt University Medical Center Nashville Tennessee USA.
Teach SJ; Center for Translational Research Children's National Hospital Washington DC USA.
Wheatley LM; Division of Allergy, Immunology, and Transplantation National Institute of Allergy and Infectious Diseases National Institutes of Health Rockville Maryland USA.
Togias A; Division of Allergy, Immunology, and Transplantation National Institute of Allergy and Infectious Diseases National Institutes of Health Rockville Maryland USA.
Busse WW; Departments of Pediatrics and Medicine University of Wisconsin School of Medicine and Public Health Madison Wisconsin USA.
Jackson DJ; Departments of Pediatrics and Medicine University of Wisconsin School of Medicine and Public Health Madison Wisconsin USA.
Sette A; Division of Vaccine Discovery La Jolla Institute for Immunology La Jolla California USA.; Department of Medicine University of California San Diego La Jolla California USA.
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Źródło:
Clinical and translational allergy [Clin Transl Allergy] 2021 Oct 13; Vol. 11 (8), pp. e12073. Date of Electronic Publication: 2021 Oct 13 (Print Publication: 2021).
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Second-hand smoke and NFE2L2 genotype interaction increases paediatric asthma risk and severity.
Autorzy:
Johansson E; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Martin LJ; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
He H; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Chen X; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Weirauch MT; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Divisions of Biomedical Informatics and Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Kroner JW; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Khurana Hershey GK; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Biagini JM; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
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Źródło:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2021 Jun; Vol. 51 (6), pp. 801-810. Date of Electronic Publication: 2021 Feb 13.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Asthma/*genetics
NF-E2-Related Factor 2/*genetics
Tobacco Smoke Pollution/*statistics & numerical data
Asthma/epidemiology ; Asthma/etiology ; Child ; Child, Preschool ; Female ; Gene-Environment Interaction ; Genetic Predisposition to Disease ; Humans ; Male ; Polymorphism, Single Nucleotide ; Severity of Illness Index ; Tobacco Smoke Pollution/adverse effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Sensitization to peanut, egg or pets is associated with skin barrier dysfunction in children with atopic dermatitis.
Autorzy:
Sherenian MG; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Kothari A; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Biagini JM; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Kroner JW; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Baatyrbek Kyzy A; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Johannson E; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Atluri G; Department of Electrical Engineering and Computer Science, University of Cincinnati, Cincinnati, OH, USA.
He H; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Martin LJ; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Khurana Hershey GK; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
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Źródło:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2021 May; Vol. 51 (5), pp. 666-673. Date of Electronic Publication: 2021 Mar 21.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Water Loss, Insensible*
Calgranulin A/*metabolism
Calgranulin B/*metabolism
Dermatitis, Atopic/*immunology
Filaggrin Proteins/*metabolism
Skin/*metabolism
Animals ; Cats ; Child, Preschool ; Dermatitis, Atopic/metabolism ; Dogs ; Egg Hypersensitivity/immunology ; Egg Hypersensitivity/metabolism ; Egg Hypersensitivity/physiopathology ; Female ; Humans ; Infant ; Machine Learning ; Male ; Peanut Hypersensitivity/immunology ; Peanut Hypersensitivity/metabolism ; Peanut Hypersensitivity/physiopathology ; Pets/immunology ; Skin/physiopathology ; Skin Tests
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
TSLP contributes to allergic airway inflammation induced by diesel exhaust particle exposure in an experimental model of severe asthma.
Autorzy:
Brandt EB; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Bolcas PE; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Ruff BP; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Khurana Hershey GK; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
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Źródło:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2020 Jan; Vol. 50 (1), pp. 121-124. Date of Electronic Publication: 2019 Nov 01.
Typ publikacji:
Letter; Research Support, N.I.H., Extramural
MeSH Terms:
Vehicle Emissions*
Airway Resistance/*immunology
Asthma/*immunology
Cytokines/*immunology
Epithelial Cells/*immunology
Lung/*immunology
Particulate Matter/*immunology
Animals ; Antigens, Dermatophagoides/immunology ; Bronchi ; Bronchoalveolar Lavage Fluid/cytology ; Bronchoalveolar Lavage Fluid/immunology ; Cell Line ; Cytokines/genetics ; Disease Models, Animal ; Epithelial Cells/metabolism ; Immunity, Innate/immunology ; Immunoglobulins/genetics ; Lung/pathology ; Macrophages, Alveolar/immunology ; Mice ; Mice, Knockout ; Pyroglyphidae ; RNA, Messenger/metabolism ; Receptors, Cytokine/genetics ; Respiratory Mucosa/immunology ; Respiratory Mucosa/metabolism ; Th2 Cells ; Thymic Stromal Lymphopoietin
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Children's Respiratory and Environmental Workgroup (CREW) birth cohort consortium: design, methods, and study population.
Autorzy:
Gern JE; University of Wisconsin School of Medicine and Public Health, Madison, WI, 53706, USA. .; Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin-Madison, Clinical Science Center-K4/918, 600 Highland Ave, Madison, WI, 53792-9988, USA. .
Jackson DJ; University of Wisconsin School of Medicine and Public Health, Madison, WI, 53706, USA.
Lemanske RF Jr; University of Wisconsin School of Medicine and Public Health, Madison, WI, 53706, USA.
Seroogy CM; University of Wisconsin School of Medicine and Public Health, Madison, WI, 53706, USA.
Tachinardi U; University of Wisconsin School of Medicine and Public Health, Madison, WI, 53706, USA.
Craven M; University of Wisconsin School of Medicine and Public Health, Madison, WI, 53706, USA.
Hwang SY; RTI International, East Cornwallis Road, Post Office Box 12194, Raleigh, Research Triangle Park, NC, 27709-2194, USA.
Hamilton CM; RTI International, East Cornwallis Road, Post Office Box 12194, Raleigh, Research Triangle Park, NC, 27709-2194, USA.
Huggins W; RTI International, East Cornwallis Road, Post Office Box 12194, Raleigh, Research Triangle Park, NC, 27709-2194, USA.
O'Connor GT; Boston University School of Medicine, 72 E Concord St, Boston, MA, 02118, USA.
Gold DR; Channing Laboratory, Brigham and Women's Hospital, Boston, MA, 02115, USA.
Miller R; Columbia University, Vagelos College of Physicians and Surgeons, New York, NY, 10032, USA.
Kattan M; Columbia University, Vagelos College of Physicians and Surgeons, New York, NY, 10032, USA.
Johnson CC; Henry Ford Health System, Detroit, MI, 48202, USA.
Ownby D; Henry Ford Health System, Detroit, MI, 48202, USA.
Zoratti EM; Henry Ford Health System, Detroit, MI, 48202, USA.
Wood RA; Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Visness CM; Rho Federal Systems Division, Inc., Chapel Hill, NC, 27517, USA.
Martinez F; University of Arizona, Tucson, AZ, 85721, USA.
Wright A; University of Arizona, Tucson, AZ, 85721, USA.
Lynch S; University of California, San Francisco, CA, 94143, USA.
Ober C; University of Chicago, Chicago, IL, 60637, USA.
Khurana Hershey GK; University of Cincinnati, Cincinnati, OH, 45220, USA.
Ryan P; University of Cincinnati, Cincinnati, OH, 45220, USA.
Hartert T; Vanderbilt University School of Medicine, Nashville, TN, 37232, USA.
Bacharier LB; Washington University School of Medicine, St. Louis, MO, 63110, USA.
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Źródło:
Respiratory research [Respir Res] 2019 Jun 10; Vol. 20 (1), pp. 115. Date of Electronic Publication: 2019 Jun 10.
Typ publikacji:
Journal Article
MeSH Terms:
Life Style*
Asthma/*diagnosis
Asthma/*epidemiology
Environmental Exposure/*analysis
Population Surveillance/*methods
Adolescent ; Asthma/genetics ; Child ; Child, Preschool ; Cohort Studies ; Environmental Exposure/prevention & control ; Female ; Humans ; Infant ; Male ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Identification of two early life eczema and non-eczema phenotypes with high risk for asthma development.
Autorzy:
Johansson E; Department of Pediatrics, University of Cincinnati, Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Biagini Myers JM; Department of Pediatrics, University of Cincinnati, Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Martin LJ; Department of Pediatrics, University of Cincinnati, Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
He H; Department of Pediatrics, University of Cincinnati, Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Ryan P; Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio.
LeMasters GK; Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio.
Bernstein DI; Department of Internal Medicine, University of Cincinnati, Cincinnati, Ohio.
Lockey J; Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio.
Khurana Hershey GK; Department of Pediatrics, University of Cincinnati, Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
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Źródło:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2019 Jun; Vol. 49 (6), pp. 829-837. Date of Electronic Publication: 2019 Mar 27.
Typ publikacji:
Clinical Trial; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Alleles*
Polymorphism, Genetic*
Asthma/*genetics
Eczema/*genetics
Kinesins/*genetics
Child ; Child, Preschool ; Female ; Humans ; Infant ; Male
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Rational targeting Cdc42 restrains Th2 cell differentiation and prevents allergic airway inflammation.
Autorzy:
Yang JQ; Division of Experimental Hematology and Cancer Biology, Children's Hospital Medical Center, Cincinnati, Ohio.; Key Laboratory of National Health Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasitic and Vector Control, Jiangsu Institute of Parasitic Diseases and Public Health Research Center, Jiangnan University, Wuxi, Jiangsu, China.
Kalim KW; Division of Experimental Hematology and Cancer Biology, Children's Hospital Medical Center, Cincinnati, Ohio.
Li Y; Division of Experimental Hematology and Cancer Biology, Children's Hospital Medical Center, Cincinnati, Ohio.
Duan X; Division of Experimental Hematology and Cancer Biology, Children's Hospital Medical Center, Cincinnati, Ohio.
Nguyen P; Division of Experimental Hematology and Cancer Biology, Children's Hospital Medical Center, Cincinnati, Ohio.
Khurana Hershey GK; Division of Asthma Research, Children's Hospital Medical Center, Cincinnati, Ohio.
Kroner J; Division of Asthma Research, Children's Hospital Medical Center, Cincinnati, Ohio.
Ruff B; Division of Asthma Research, Children's Hospital Medical Center, Cincinnati, Ohio.
Zhang L; Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio.
Salomonis N; Division of Biomedical Informatics, Children's Hospital Medical Center, Cincinnati, Ohio.
Rochman M; Division of Allergy and Immunology, Children's Hospital Medical Center, Cincinnati, Ohio.
Wen T; Division of Allergy and Immunology, Children's Hospital Medical Center, Cincinnati, Ohio.
Zheng Y; Division of Experimental Hematology and Cancer Biology, Children's Hospital Medical Center, Cincinnati, Ohio.
Guo F; Division of Experimental Hematology and Cancer Biology, Children's Hospital Medical Center, Cincinnati, Ohio.
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Źródło:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2019 Jan; Vol. 49 (1), pp. 92-107. Date of Electronic Publication: 2018 Nov 13.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Asthma*/genetics
Asthma*/immunology
Asthma*/pathology
Cell Differentiation*/genetics
Cell Differentiation*/immunology
cdc42 GTP-Binding Protein*/genetics
cdc42 GTP-Binding Protein*/immunology
Th2 Cells/*immunology
Animals ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/pathology ; Gene Deletion ; Mice ; Mice, Transgenic ; Th2 Cells/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Ohio Pediatric Asthma Repository: Opportunities to Revise Care Practices to Decrease Time to Physiologic Readiness for Discharge.
Autorzy:
Simmons JM; Divisions of Hospital Medicine.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Biagini Myers JM; Asthma Research.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Martin LJ; Human Genetics, and.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Kercsmar CM; Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Schuler CL; Divisions of Hospital Medicine.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Pilipenko VV; Human Genetics, and.
Kroner JW; Asthma Research.
He H; Human Genetics, and.
Austin SR; Asthma Research.
Nguyen HT; Asthma Research.
Ross KR; Department of Pediatrics-Pulmonary, Rainbow Babies and Children's Hospital, Cleveland, Ohio.
McCoy KS; Division of Pediatric Pulmonology, Nationwide Children's Hospital, Columbus, Ohio.
Alter SJ; Department of Infectious Disease, Dayton Children's Hospital, Dayton, Ohio.
Gunkelman SM; Division of Pediatric Hospital Medicine, Akron Children's Hospital, Akron, Ohio.
Vauthy PA; Department of Pediatric Pulmonary Medicine, ProMedica Toledo Children's Hospital, Toledo, Ohio; and.
Khurana Hershey GK; Asthma Research, gurjit.hershey@cchmc.org.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
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Źródło:
Hospital pediatrics [Hosp Pediatr] 2018 Jun; Vol. 8 (6), pp. 305-313. Date of Electronic Publication: 2018 May 15.
Typ publikacji:
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Emergency Service, Hospital*
Guideline Adherence*
Patient Discharge*/statistics & numerical data
Anti-Asthmatic Agents/*administration & dosage
Asthma/*therapy
Hospitalization/*statistics & numerical data
Adolescent ; Asthma/epidemiology ; Asthma/physiopathology ; Child ; Child, Preschool ; Dexamethasone/administration & dosage ; Female ; Humans ; Male ; Ohio/epidemiology ; Practice Guidelines as Topic ; Prednisone/administration & dosage ; Prospective Studies ; Radiography, Thoracic/statistics & numerical data
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Nasal DNA methylation differentiates corticosteroid treatment response in pediatric asthma: A pilot study.
Autorzy:
Zhang X; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.; Pyrosequencing lab for genomic and epigenomic research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.
Biagini Myers JM; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America.
Yadagiri VK; Pyrosequencing lab for genomic and epigenomic research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.
Ulm A; Pyrosequencing lab for genomic and epigenomic research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.
Chen X; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.
Weirauch MT; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America.; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.; Divisions of Biomedical Informatics and Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.
Khurana Hershey GK; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America.
Ji H; Pyrosequencing lab for genomic and epigenomic research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America.
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Źródło:
PloS one [PLoS One] 2017 Oct 13; Vol. 12 (10), pp. e0186150. Date of Electronic Publication: 2017 Oct 13 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Adrenal Cortex Hormones/*pharmacology
Asthma/*drug therapy
Asthma/*genetics
DNA Methylation/*drug effects
Nasal Mucosa/*metabolism
Adolescent ; Adrenal Cortex Hormones/therapeutic use ; Child ; Female ; Gene Expression Regulation/drug effects ; Genetic Markers/genetics ; Humans ; Male ; Pilot Projects ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Endotypes of difficult-to-control asthma in inner-city African American children.
Autorzy:
Brown KR; Department of Pediatrics, Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, United States of America.
Krouse RZ; Rho Federal Systems Division Inc., Chapel Hill, North Carolina, United States of America.
Calatroni A; Rho Federal Systems Division Inc., Chapel Hill, North Carolina, United States of America.
Visness CM; Rho Federal Systems Division Inc., Chapel Hill, North Carolina, United States of America.
Sivaprasad U; Department of Pediatrics, Division of Asthma Research, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, United States of America.
Kercsmar CM; Department of Pediatrics, Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, United States of America.
Matsui EC; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
West JB; Boston University School of Medicine, Boston, Massachusetts, United States of America.
Makhija MM; Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States of America.
Gill MA; University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
Kim H; Henry Ford Health System, Detroit, Michigan, United States of America.
Kattan M; College of Physicians and Surgeons, Columbia University, New York, New York, United States of America.
Pillai D; Children's National Health System, Washington, District of Columbia, United States of America.
Gern JE; University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.
Busse WW; University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.
Togias A; National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, United States of America.
Liu AH; National Jewish Health, Denver, Colorado, United States of America.; Children's Hospital Colorado and University of Colorado School of Medicine, Aurora, Colorado, United States of America.
Khurana Hershey GK; Department of Pediatrics, Division of Asthma Research, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, United States of America.
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Źródło:
PloS one [PLoS One] 2017 Jul 07; Vol. 12 (7), pp. e0180778. Date of Electronic Publication: 2017 Jul 07 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Asthmatic Agents/*administration & dosage
Asthma/*blood
Asthma/*drug therapy
Cytokines/*blood
Adolescent ; Black or African American ; Asthma/pathology ; Blood Cell Count ; Child ; Eosinophils/pathology ; Female ; Humans ; Male ; Neutrophils/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Rhinovirus infection results in stronger and more persistent genomic dysregulation: Evidence for altered innate immune response in asthmatics at baseline, early in infection, and during convalescence.
Autorzy:
Heymann PW; Division of Allergy, Immunology and Respiratory Medicine, Department of Pediatrics, University of Virginia, Charlottesville, Virginia, United States of America.; Department of Internal Medicine, Asthma and Allergic Diseases Center, University of Virginia, Charlottesville, Virginia, United States of America.
Nguyen HT; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio, United States of America.; Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio, United States of America.
Steinke JW; Department of Internal Medicine, Asthma and Allergic Diseases Center, University of Virginia, Charlottesville, Virginia, United States of America.
Turner RB; Division of Infectious Diseases, Department of Pediatrics, University of Virginia, Charlottesville, Virginia, United States of America.
Woodfolk JA; Department of Internal Medicine, Asthma and Allergic Diseases Center, University of Virginia, Charlottesville, Virginia, United States of America.
Platts-Mills TAE; Department of Internal Medicine, Asthma and Allergic Diseases Center, University of Virginia, Charlottesville, Virginia, United States of America.
Martin L; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio, United States of America.
He H; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio, United States of America.
Biagini Myers J; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio, United States of America.
Lindsey M; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio, United States of America.
Sivaprasad U; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio, United States of America.
Medvedovic M; Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio, United States of America.
Mahi N; Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio, United States of America.
Carper H; Division of Allergy, Immunology and Respiratory Medicine, Department of Pediatrics, University of Virginia, Charlottesville, Virginia, United States of America.
Murphy DD; Division of Allergy, Immunology and Respiratory Medicine, Department of Pediatrics, University of Virginia, Charlottesville, Virginia, United States of America.
Patrie J; Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, United States of America.
Khurana Hershey GK; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio, United States of America.
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Źródło:
PloS one [PLoS One] 2017 May 26; Vol. 12 (5), pp. e0178096. Date of Electronic Publication: 2017 May 26 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Immunity, Innate*
Picornaviridae Infections/*immunology
Rhinovirus/*pathogenicity
Adult ; Asthma/immunology ; Case-Control Studies ; Female ; Humans ; Male ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Correction: IL-31-Driven Skin Remodeling Involves Epidermal Cell Proliferation and Thickening That Lead to Impaired Skin-Barrier Function.
Autorzy:
Singh B
Jegga AG
Shanmukhappa KS
Edukulla R
Khurana Hershey GK
Medvedovic M
Dillon SR
Madala SK
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Źródło:
PloS one [PLoS One] 2017 Jan 23; Vol. 12 (1), pp. e0170446. Date of Electronic Publication: 2017 Jan 23 (Print Publication: 2017).
Typ publikacji:
Journal Article; Published Erratum
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Air pollution, epigenetics, and asthma.
Autorzy:
Ji H; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave. MLC 7037, Cincinnati, OH 45229 USA ; Pyrosequencing lab for Genomic and Epigenomic research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229 USA.
Biagini Myers JM; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave. MLC 7037, Cincinnati, OH 45229 USA.
Brandt EB; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave. MLC 7037, Cincinnati, OH 45229 USA.
Brokamp C; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229 USA.
Ryan PH; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229 USA.
Khurana Hershey GK; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave. MLC 7037, Cincinnati, OH 45229 USA.
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Źródło:
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology [Allergy Asthma Clin Immunol] 2016 Oct 19; Vol. 12, pp. 51. Date of Electronic Publication: 2016 Oct 19 (Print Publication: 2016).
Typ publikacji:
Review; Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Multiple Transcriptome Data Analysis Reveals Biologically Relevant Atopic Dermatitis Signature Genes and Pathways.
Autorzy:
Ghosh D; Division of Immunology, Allergy & Rheumatology, Department of Internal Medicine, University of Cincinnati, Cincinnati, United States of America.
Ding L; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, United States of America.
Sivaprasad U; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, United States of America.
Geh E; Division of Immunology, Allergy & Rheumatology, Department of Internal Medicine, University of Cincinnati, Cincinnati, United States of America.
Biagini Myers J; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, United States of America.
Bernstein JA; Division of Immunology, Allergy & Rheumatology, Department of Internal Medicine, University of Cincinnati, Cincinnati, United States of America.
Khurana Hershey GK; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, United States of America.
Mersha TB; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, United States of America.
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Źródło:
PloS one [PLoS One] 2015 Dec 30; Vol. 10 (12), pp. e0144316. Date of Electronic Publication: 2015 Dec 30 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Profiling*
Transcriptome*
Dermatitis, Atopic/*genetics
Animals ; Case-Control Studies ; Cell Differentiation/genetics ; Cluster Analysis ; Computational Biology/methods ; Databases, Genetic ; Dermatitis, Atopic/metabolism ; Discriminant Analysis ; Filaggrin Proteins ; Gene Expression Regulation ; Gene Regulatory Networks ; Humans ; Keratinocytes/cytology ; Keratinocytes/metabolism ; Mice ; Molecular Sequence Annotation ; Reproducibility of Results ; Signal Transduction ; Support Vector Machine
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
N-acetyltransferase 1 polymorphism increases cotinine levels in Caucasian children exposed to secondhand smoke: the CCAAPS birth cohort.
Autorzy:
LeMasters GK; Department of Environmental Health, University of Cincinnati, Cincinnati, OH, USA.
Khurana Hershey GK; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Sivaprasad U; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Martin LJ; 1] Division of Human Genetics, Cinc innati Children's Hospital Medical Center, Cincinnati, OH, USA [2] Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Pilipenko V; Division of Human Genetics, Cinc innati Children's Hospital Medical Center, Cincinnati, OH, USA.
Ericksen MB; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Burkle JW; Department of Environmental Health, University of Cincinnati, Cincinnati, OH, USA.
Lindsey MA; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Bernstein DI; Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA.
Lockey JE; Department of Environmental Health, University of Cincinnati, Cincinnati, OH, USA.
Gareri J; Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, Ontario, Canada.
Lubetsky A; Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, Ontario, Canada.
Koren G; Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, Ontario, Canada.
Biagini Myers JM; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
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Źródło:
The pharmacogenomics journal [Pharmacogenomics J] 2015 Apr; Vol. 15 (2), pp. 189-95. Date of Electronic Publication: 2014 Aug 26.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Arylamine N-Acetyltransferase/*genetics
Cotinine/*metabolism
Isoenzymes/*genetics
Polymorphism, Single Nucleotide/*genetics
White People/*genetics
Alleles ; Biomarkers/metabolism ; Child ; Child, Preschool ; Female ; Genotype ; Humans ; Infant ; Male ; Nicotine/adverse effects ; Nicotine/metabolism ; Smoking/adverse effects ; Smoking/metabolism ; Tobacco Smoke Pollution
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Duration of day care attendance during infancy predicts asthma at the age of seven: the Cincinnati Childhood Allergy and Air Pollution Study.
Autorzy:
Cheng G; Division of Immunology, Allergy and Rheumatology, University of Cincinnati Medical Center, Cincinnati, OH, USA.
Smith AM
Levin L
Epstein T
Ryan PH
LeMasters GK
Khurana Hershey GK
Reponen T
Villareal M
Lockey J
Bernstein DI
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Źródło:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2014 Oct; Vol. 44 (10), pp. 1274-81.
Typ publikacji:
Journal Article
MeSH Terms:
Child Day Care Centers*
Air Pollution/*adverse effects
Asthma/*etiology
Child ; Female ; Humans ; Infant ; Logistic Models ; Male ; Respiratory Tract Infections/complications ; Surveys and Questionnaires ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Diesel exhaust particle exposure increases severity of allergic asthma in young mice.
Autorzy:
Acciani TH; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Brandt EB
Khurana Hershey GK
Le Cras TD
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Źródło:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2013 Dec; Vol. 43 (12), pp. 1406-18.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Vehicle Emissions*
Asthma/*etiology
Particulate Matter/*adverse effects
Age Factors ; Air Pollutants/adverse effects ; Allergens/immunology ; Animals ; Asthma/pathology ; Bronchial Hyperreactivity/etiology ; Bronchial Hyperreactivity/pathology ; Cytokines/metabolism ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Disease Models, Animal ; Goblet Cells/pathology ; Immunoglobulin E/immunology ; Lung/immunology ; Lung/metabolism ; Lung/pathology ; Metaplasia ; Mice ; Particulate Matter/immunology ; Severity of Illness Index ; T-Lymphocyte Subsets/immunology ; T-Lymphocyte Subsets/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Diesel exhaust particles induce cysteine oxidation and s-glutathionylation in house dust mite induced murine asthma.
Autorzy:
Lee GB; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.
Brandt EB
Xiao C
Gibson AM
Le Cras TD
Brown LA
Fitzpatrick AM
Khurana Hershey GK
Pokaż więcej
Źródło:
PloS one [PLoS One] 2013; Vol. 8 (3), pp. e60632. Date of Electronic Publication: 2013 Mar 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Asthma/*etiology
Cysteine/*analogs & derivatives
Cysteine/*analysis
Glutathione/*analogs & derivatives
Glutathione/*analysis
Particulate Matter/*adverse effects
Air Pollutants/adverse effects ; Animals ; Asthma/immunology ; Asthma/metabolism ; Bronchi/cytology ; Bronchi/immunology ; Bronchi/metabolism ; Bronchoalveolar Lavage Fluid/chemistry ; Cell Line ; Cysteine/immunology ; Cysteine/metabolism ; Cystine/analysis ; Cystine/immunology ; Cystine/metabolism ; Glutathione/immunology ; Glutathione/metabolism ; Glutathione Disulfide/analysis ; Glutathione Disulfide/immunology ; Glutathione Disulfide/metabolism ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Oxidation-Reduction ; Oxidative Stress ; Pyroglyphidae/immunology ; Vehicle Emissions/analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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