Autor: "Kielbasa SM" - OpacWWW

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Tytuł:: MDMX Regulates Transcriptional Activity of p53 and FOXO Proteins to Stimulate Proliferation of Melanoma Cells.
Autorzy:: Heijkants RC; Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Teunisse AFAS; Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
de Jong D; Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Glinkina K; Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Mei H; Sequencing Analysis Support Core, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Kielbasa SM; Sequencing Analysis Support Core, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.; Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Szuhai K; Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Jochemsen AG; Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.; Pokaż więcej
Źródło:: Cancers [Cancers (Basel)] 2022 Sep 15; Vol. 14 (18). Date of Electronic Publication: 2022 Sep 15.
Typ publikacji:: Journal Article

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Skocz do pozycji: 5.

Tytuł:: Hippocampal glucocorticoid target genes associated with enhancement of memory consolidation.
Autorzy:: Buurstede JC; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.
van Weert LTCM; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.; Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands.
Colucci P; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy.
Gentenaar M; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Viho EMG; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Koorneef LL; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Schoonderwoerd RA; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Lanooij SD; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Moustakas I; Sequencing Analysis Support Core, Leiden University Medical Center, Leiden, The Netherlands.
Balog J; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Mei H; Sequencing Analysis Support Core, Leiden University Medical Center, Leiden, The Netherlands.
Kielbasa SM; Department of Medical Statistics and Bioinformatics, Bioinformatics Center of Expertise, Leiden University Medical Center, Leiden, The Netherlands.
Campolongo P; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy.
Roozendaal B; Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands.
Meijer OC; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2022 May; Vol. 55 (9-10), pp. 2666-2683. Date of Electronic Publication: 2021 May 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Glucocorticoids*/metabolism
Glucocorticoids*/pharmacology
Memory Consolidation*
Animals ; Corticosterone/metabolism ; Corticosterone/pharmacology ; DNA/metabolism ; Hippocampus/metabolism ; Male ; Rats ; Receptors, Glucocorticoid/genetics ; Receptors, Glucocorticoid/metabolism

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Skocz do pozycji: 6.

Tytuł:: Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model.
Autorzy:: Toonen LJA; Department of Human Genetics, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.
Overzier M; Department of Human Genetics, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.
Evers MM; Department of Research & Development, uniQure, Amsterdam, The Netherlands.
Leon LG; Cancer Pharmacology Lab, University of Pisa, Ospedale di Cisanello, Edificio 6 via Paradisa, 2, 56124, Pisa, Italy.
van der Zeeuw SAJ; Sequencing Analysis Support Core, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.
Mei H; Sequencing Analysis Support Core, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.
Kielbasa SM; Department of Biomedical Data Sciences, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.
Goeman JJ; Department of Biomedical Data Sciences, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.
Hettne KM; Department of Human Genetics, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.
Magnusson OT; deCODE genetics/Amgen, Sturlugata 8, 101, Reykjavik, Iceland.
Poirel M; MedDAY Pharmaceuticals, Paris, France.
Seyer A; MedDAY Pharmaceuticals, Paris, France.
't Hoen PAC; Department of Human Genetics, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.; Centre for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6500 HB, Nijmegen, The Netherlands.
van Roon-Mom WMC; Department of Human Genetics, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands. .; Pokaż więcej
Źródło:: Molecular neurodegeneration [Mol Neurodegener] 2018 Jun 22; Vol. 13 (1), pp. 31. Date of Electronic Publication: 2018 Jun 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Brain/*metabolism
Brain/*pathology
Machado-Joseph Disease/*metabolism
Machado-Joseph Disease/*pathology
Animals ; Ataxin-3/genetics ; Disease Models, Animal ; Gene Expression Profiling ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Transcriptome

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Skocz do pozycji: 7.

Tytuł:: A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts.
Autorzy:: Blüthgen N; Institute for Theoretical Biology, Humboldt University, Berlin, Germany. />Legewie S
Kielbasa SM
Schramme A
Tchernitsa O
Keil J
Solf A
Vingron M
Schäfer R
Herzel H
Sers C; Pokaż więcej
Źródło:: The FEBS journal [FEBS J] 2009 Feb; Vol. 276 (4), pp. 1024-35. Date of Electronic Publication: 2009 Jan 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Feedback, Physiological*
Genes, ras*
Models, Biological*
Dual Specificity Phosphatase 6/*physiology
Extracellular Signal-Regulated MAP Kinases/*metabolism
Animals ; Cells, Cultured ; Fibroblasts/metabolism ; Humans ; MAP Kinase Signaling System/physiology ; Mice ; Oligonucleotide Array Sequence Analysis ; Phosphorylation ; RNA Stability ; RNA, Messenger/metabolism ; Rats ; Signal Transduction/physiology ; Systems Biology

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Skocz do pozycji: 8.

Tytuł:: Regulation of clock-controlled genes in mammals.
Autorzy:: Bozek K; Max Planck Institute for Informatics, Saarbrücken, Germany.
Relógio A
Kielbasa SM
Heine M
Dame C
Kramer A
Herzel H; Pokaż więcej
Źródło:: PloS one [PLoS One] 2009; Vol. 4 (3), pp. e4882. Date of Electronic Publication: 2009 Mar 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation*
Mammals/*genetics
Trans-Activators/*genetics
Amino Acid Sequence ; Animals ; CLOCK Proteins ; Consensus Sequence ; Erythropoietin/genetics ; Kidney/metabolism ; Molecular Sequence Data ; Promoter Regions, Genetic ; Regulatory Sequences, Nucleic Acid ; Trans-Activators/chemistry ; Transcription Factors/metabolism

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Skocz do pozycji: 9.

Tytuł:: Measuring similarities between transcription factor binding sites.
Autorzy:: Kielbasa SM; Institute for Theoretical Biology, Humboldt University, Invalidenstrasse 43, D-10115 Berlin, Germany. s.kielbasa@biologie.hu-berlin.de
Gonze D
Herzel H; Pokaż więcej
Źródło:: BMC bioinformatics [BMC Bioinformatics] 2005 Sep 28; Vol. 6, pp. 237. Date of Electronic Publication: 2005 Sep 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Models, Biological*
Chromosome Mapping/*methods
Transcription Factors/*metabolism
ARNTL Transcription Factors ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Binding Sites ; Circadian Rhythm/genetics ; Databases, Nucleic Acid ; E-Box Elements/physiology ; Nucleotides/analysis ; Sensitivity and Specificity ; Sequence Analysis, DNA/methods

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