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Tytuł:
Intranasal challenge with B. pertussis leads to more severe disease manifestations in mice than aerosol challenge.
Autorzy:
Weaver KL; Vaccine Development Center in the Department of Microbiology, Immunology, and Cell Biology at West Virginia University, Morgantown, WV, United States of America.
Bitzer GJ; Vaccine Development Center in the Department of Microbiology, Immunology, and Cell Biology at West Virginia University, Morgantown, WV, United States of America.
Wolf MA; Vaccine Development Center in the Department of Microbiology, Immunology, and Cell Biology at West Virginia University, Morgantown, WV, United States of America.
Pyles GM; Vaccine Development Center in the Department of Microbiology, Immunology, and Cell Biology at West Virginia University, Morgantown, WV, United States of America.
DeJong MA; Vaccine Development Center in the Department of Microbiology, Immunology, and Cell Biology at West Virginia University, Morgantown, WV, United States of America.
Dublin SR; Vaccine Development Center in the Department of Microbiology, Immunology, and Cell Biology at West Virginia University, Morgantown, WV, United States of America.
Huckaby AB; Vaccine Development Center in the Department of Microbiology, Immunology, and Cell Biology at West Virginia University, Morgantown, WV, United States of America.
Gutierrez MP; Vaccine Development Center in the Department of Microbiology, Immunology, and Cell Biology at West Virginia University, Morgantown, WV, United States of America.
Hall JM; Vaccine Development Center in the Department of Microbiology, Immunology, and Cell Biology at West Virginia University, Morgantown, WV, United States of America.
Wong TY; Vaccine Development Center in the Department of Microbiology, Immunology, and Cell Biology at West Virginia University, Morgantown, WV, United States of America.
Warden M; Vaccine Development Center in the Department of Microbiology, Immunology, and Cell Biology at West Virginia University, Morgantown, WV, United States of America.
Petty JE; Vaccine Development Center in the Department of Microbiology, Immunology, and Cell Biology at West Virginia University, Morgantown, WV, United States of America.
Witt WT; Vaccine Development Center in the Department of Microbiology, Immunology, and Cell Biology at West Virginia University, Morgantown, WV, United States of America.
Cunningham C; Vaccine Development Center in the Department of Microbiology, Immunology, and Cell Biology at West Virginia University, Morgantown, WV, United States of America.
Sen-Kilic E; Vaccine Development Center in the Department of Microbiology, Immunology, and Cell Biology at West Virginia University, Morgantown, WV, United States of America.
Damron FH; Vaccine Development Center in the Department of Microbiology, Immunology, and Cell Biology at West Virginia University, Morgantown, WV, United States of America.
Barbier M; Vaccine Development Center in the Department of Microbiology, Immunology, and Cell Biology at West Virginia University, Morgantown, WV, United States of America.
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Źródło:
PloS one [PLoS One] 2023 Nov 02; Vol. 18 (11), pp. e0286925. Date of Electronic Publication: 2023 Nov 02 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:
Bordetella pertussis*
Whooping Cough*
Animals ; Mice ; Mice, Inbred BALB C ; Respiratory Aerosols and Droplets ; Administration, Intranasal ; Pertussis Vaccine
Czasopismo naukowe
Tytuł:
Nanodrugs for the Treatment of Ischemic Stroke: A Systematic Review.
Autorzy:
Ruscu M; Doctoral School, University of Medicine and Pharmacy Craiova, 200349 Craiova, Romania.
Cercel A; Doctoral School, University of Medicine and Pharmacy Craiova, 200349 Craiova, Romania.
Kilic E; Department of Physiology, School of Medicine, Istanbul Medipol University, Istanbul 34214, Turkey.
Catalin B; Doctoral School, University of Medicine and Pharmacy Craiova, 200349 Craiova, Romania.
Gresita A; Department of Biomedical Sciences, New York Institute of Technology, College of Osteopathic Medicine, Old Westbury, NY 115680-8000, USA.
Hermann DM; Doctoral School, University of Medicine and Pharmacy Craiova, 200349 Craiova, Romania.; Department of Neurology, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Albu CV; Department of Neurology, University of Medicine and Pharmacy Craiova, 200349 Craiova, Romania.
Popa-Wagner A; Doctoral School, University of Medicine and Pharmacy Craiova, 200349 Craiova, Romania.; Department of Neurology, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 28; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 28.
Typ publikacji:
Systematic Review; Journal Article; Review
MeSH Terms:
Stroke*/drug therapy
Ischemic Stroke*/drug therapy
Nanoparticles*/therapeutic use
Brain Ischemia*/drug therapy
Animals ; Tissue Distribution ; Anti-Inflammatory Agents
Czasopismo naukowe
Tytuł:
Reduced folate carrier 1 is present in retinal microvessels and crucial for the inner blood retinal barrier integrity.
Autorzy:
Gurler G; The Institute of Neurological Sciences and Psychiatry, Hacettepe University, Ankara, Turkey.
Belder N; Biotechnology Institute, Ankara University, Ankara, Turkey.
Beker MC; Physiology, Istanbul Medipol University, Istanbul, Turkey.
Sever-Bahcekapili M; The Institute of Neurological Sciences and Psychiatry, Hacettepe University, Ankara, Turkey.
Uruk G; The Institute of Neurological Sciences and Psychiatry, Hacettepe University, Ankara, Turkey.
Kilic E; Neuroscience and Neurotechnology Center of Excellence (NÖROM), Ankara, Turkey.; Physiology, Istanbul Medeniyet University, Istanbul, Turkey.
Yemisci M; The Institute of Neurological Sciences and Psychiatry, Hacettepe University, Ankara, Turkey. .; Faculty of Medicine, Department of Neurology, Hacettepe University, Ankara, Turkey. .; Neuroscience and Neurotechnology Center of Excellence (NÖROM), Ankara, Turkey. .
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Źródło:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2023 Jun 16; Vol. 20 (1), pp. 47. Date of Electronic Publication: 2023 Jun 16.
Typ publikacji:
Journal Article
MeSH Terms:
Blood-Retinal Barrier*/metabolism
Endothelial Cells*/metabolism
Reduced Folate Carrier Protein*/genetics
Reduced Folate Carrier Protein*/metabolism
Animals ; Mice ; Folic Acid/metabolism ; Immunoglobulin G ; Occludin/metabolism ; RNA, Small Interfering/metabolism ; Trypsin/metabolism
Czasopismo naukowe
Tytuł:
P. aeruginosa type III and type VI secretion systems modulate early response gene expression in type II pneumocytes in vitro.
Autorzy:
Sen-Kilic E; Department of Microbiology, Immunology, and Cell Biology, West Virginia University School of Medicine, Morgantown, WV, USA.; Vaccine Development Center, West Virginia University Health Sciences Center, Morgantown, WV, USA.
Huckaby AB; Department of Microbiology, Immunology, and Cell Biology, West Virginia University School of Medicine, Morgantown, WV, USA.; Vaccine Development Center, West Virginia University Health Sciences Center, Morgantown, WV, USA.
Damron FH; Department of Microbiology, Immunology, and Cell Biology, West Virginia University School of Medicine, Morgantown, WV, USA.; Vaccine Development Center, West Virginia University Health Sciences Center, Morgantown, WV, USA.
Barbier M; Department of Microbiology, Immunology, and Cell Biology, West Virginia University School of Medicine, Morgantown, WV, USA. .; Vaccine Development Center, West Virginia University Health Sciences Center, Morgantown, WV, USA. .
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Źródło:
BMC genomics [BMC Genomics] 2022 May 04; Vol. 23 (1), pp. 345. Date of Electronic Publication: 2022 May 04.
Typ publikacji:
Journal Article
MeSH Terms:
Pseudomonas aeruginosa*/genetics
Type VI Secretion Systems*/genetics
Alveolar Epithelial Cells/metabolism ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Gene Expression ; Gene Expression Regulation, Bacterial ; Transcription Factors/metabolism ; Type III Secretion Systems/genetics ; Virulence Factors/genetics
Czasopismo naukowe
Tytuł:
Genome-wide aberrant methylation in primary metastatic UM and their matched metastases.
Autorzy:
Smit KN; Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands.
Boers R; Oncode Institute, Department of Developmental Biology, Erasmus MC, Rotterdam, The Netherlands.
Vaarwater J; Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands.
Boers J; Oncode Institute, Department of Developmental Biology, Erasmus MC, Rotterdam, The Netherlands.
Brands T; Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands.
Mensink H; The Rotterdam Eye Hospital, Rotterdam, The Netherlands.
Verdijk RM; Department of Pathology, Section Ophthalmic Pathology, Erasmus MC, Rotterdam, The Netherlands.
van IJcken WFJ; Center for Biomics, Department of Cell Biology, Erasmus MC, Rotterdam, The Netherlands.
Gribnau J; Oncode Institute, Department of Developmental Biology, Erasmus MC, Rotterdam, The Netherlands.
de Klein A; Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands.
Kilic E; Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands. e.kilic@erasmusmc.nl.
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Źródło:
Scientific reports [Sci Rep] 2022 Jan 07; Vol. 12 (1), pp. 42. Date of Electronic Publication: 2022 Jan 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Melanoma/*genetics
Melanoma/*metabolism
Neoplasm Metastasis/*genetics
Uveal Neoplasms/*genetics
Uveal Neoplasms/*metabolism
DNA Mutational Analysis ; Epigenesis, Genetic ; Gene Expression Regulation, Neoplastic ; Humans ; Methylation ; Phosphoproteins/genetics ; Phosphoproteins/metabolism ; RNA Splicing Factors/genetics ; RNA Splicing Factors/metabolism ; Tumor Suppressor Proteins/genetics ; Tumor Suppressor Proteins/metabolism ; Ubiquitin Thiolesterase/genetics ; Ubiquitin Thiolesterase/metabolism
SCR Disease Name:
Uveal melanoma
Czasopismo naukowe
Tytuł:
The Effect of Intraocular Pressure-Lowering Medication on Metastatic Uveal Melanomas.
Autorzy:
Pals J; Department of Ophthalmology, Erasmus University Medical Center, 3015 CA Rotterdam, The Netherlands.
Mensink HW; The Rotterdam Eye Hospital, 3011 BH Rotterdam, The Netherlands.
Brosens E; Department of Clinical Genetics, Erasmus University Medical Center, 3015 CA Rotterdam, The Netherlands.
Verdijk RM; Department of Pathology, Section Ophthalmic Pathology, Erasmus University Medical Center, 3015 CA Rotterdam, The Netherlands.; Department of Pathology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Naus NC; Department of Ophthalmology, Erasmus University Medical Center, 3015 CA Rotterdam, The Netherlands.
Paridaens DA; Department of Ophthalmology, Erasmus University Medical Center, 3015 CA Rotterdam, The Netherlands.; The Rotterdam Eye Hospital, 3011 BH Rotterdam, The Netherlands.
Kilic E; Department of Ophthalmology, Erasmus University Medical Center, 3015 CA Rotterdam, The Netherlands.
Ramdas WD; Department of Ophthalmology, Erasmus University Medical Center, 3015 CA Rotterdam, The Netherlands.
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Źródło:
Cancers [Cancers (Basel)] 2021 Nov 12; Vol. 13 (22). Date of Electronic Publication: 2021 Nov 12.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Radiological Patterns of Uveal Melanoma Liver Metastases in Correlation to Genetic Status.
Autorzy:
Yavuzyigitoglu S; Department of Ophthalmology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.; Department of Clinical Genetics, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
Tang MCY; Department of Ophthalmology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
Jansen M; Department of Ophthalmology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
Geul KW; Department of Internal Medicine, Sint Franciscus Gasthuis Rotterdam, 3045 PM Rotterdam, The Netherlands.
Dwarkasing RS; Department of Radiology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
Vaarwater J; Department of Ophthalmology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.; Department of Clinical Genetics, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
Drabarek W; Department of Ophthalmology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.; Department of Clinical Genetics, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
Verdijk RM; Department of Pathology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
Paridaens D; Department of Ophthalmology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.; The Rotterdam Eye Hospital, 3011 BH Rotterdam, The Netherlands.
Naus NC; Department of Ophthalmology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
Brosens E; Department of Clinical Genetics, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
de Klein A; Department of Clinical Genetics, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
Kilic E; Department of Ophthalmology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
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Źródło:
Cancers [Cancers (Basel)] 2021 Oct 22; Vol. 13 (21). Date of Electronic Publication: 2021 Oct 22.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Protective Effect of Lutein/Zeaxanthin Isomers in Traumatic Brain Injury in Mice.
Autorzy:
Gunal MY; Regenerative and Restorative Medical Research Center, Istanbul Medipol University, Istanbul, Turkey.; Department of Physiology, School of Medicine, Alanya Alaaddin Keykubat University, Antalya, Turkey.
Sakul AA; Regenerative and Restorative Medical Research Center, Istanbul Medipol University, Istanbul, Turkey.; Department of Pharmacology, School of Medicine, Istanbul Medipol University, Istanbul, Turkey.
Caglayan AB; Regenerative and Restorative Medical Research Center, Istanbul Medipol University, Istanbul, Turkey.; Department of Physiology, School of Medicine, Istanbul Medipol University, Istanbul, Turkey.
Erten F; Department of Veterinary Medicine, Pertek Sakine Genc Vocational School, Munzur University, Tunceli, Turkey.
Kursun OED; Department of Pharmacy Services, Vocational School of Kovancilar, Firat University, Elazig, Turkey.
Kilic E; Regenerative and Restorative Medical Research Center, Istanbul Medipol University, Istanbul, Turkey.; Department of Physiology, School of Medicine, Istanbul Medipol University, Istanbul, Turkey.
Sahin K; Department of Animal Nutrition, Faculty of Veterinary Medicine, Firat University, Elazig, Turkey. .
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Źródło:
Neurotoxicity research [Neurotox Res] 2021 Oct; Vol. 39 (5), pp. 1543-1550. Date of Electronic Publication: 2021 Jun 15.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants/*administration & dosage
Brain Injuries, Traumatic/*prevention & control
Lutein/*administration & dosage
Neuroprotective Agents/*administration & dosage
Oxidative Stress/*drug effects
Zeaxanthins/*administration & dosage
Animals ; Antioxidants/chemistry ; Brain Injuries, Traumatic/pathology ; Isomerism ; Lutein/chemistry ; Male ; Mice ; Mice, Inbred C57BL ; Neuroprotective Agents/chemistry ; Oxidative Stress/physiology ; Zeaxanthins/chemistry
Czasopismo naukowe
Tytuł:
A Different View on the Etiopathogenesis of Attention-deficit Hyperactivity Disorder from an Inflammation Perspective.
Autorzy:
Dursun S; Departments of Child and Adolescent Psychiatry, Kayseri, Turkey.
Demirci E; Departments of Child and Adolescent Psychiatry, Kayseri, Turkey.
Kilic E; Departments of Biochemistry, Erciyes University, Kayseri, Turkey.
Ozmen S; Departments of Child and Adolescent Psychiatry, Kayseri, Turkey.
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Źródło:
Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology [Clin Psychopharmacol Neurosci] 2021 Feb 28; Vol. 19 (1), pp. 145-154.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Circular RNAs and Their Linear Transcripts as Diagnostic and Prognostic Tissue Biomarkers in Prostate Cancer after Prostatectomy in Combination with Clinicopathological Factors.
Autorzy:
Rochow H; Department of Urology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.; Berlin Institute for Urologic Research, 10115 Berlin, Germany.
Jung M; Department of Urology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Weickmann S; Department of Urology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Ralla B; Department of Urology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Stephan C; Department of Urology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.; Berlin Institute for Urologic Research, 10115 Berlin, Germany.
Elezkurtaj S; Institute of Pathology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Kilic E; Institute of Pathology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.; Institute of Pathology, Hospital Leverkusen, 51375 Leverkusen, Germany.
Zhao Z; Department of Urology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.; Department of Urology, Qilu Hospital of Shandong University, Jinan 250012, China.
Jung K; Department of Urology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.; Berlin Institute for Urologic Research, 10115 Berlin, Germany.
Fendler A; Department of Urology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.; Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Cancer Research Program, 13125 Berlin, Germany.; Cancer Dynamics Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
Franz A; Department of Urology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 22; Vol. 21 (21). Date of Electronic Publication: 2020 Oct 22.
Typ publikacji:
Journal Article
MeSH Terms:
Biomarkers, Tumor/*genetics
Prostatic Neoplasms/*genetics
Prostatic Neoplasms/*pathology
RNA, Circular/*genetics
Aged ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Middle Aged ; Neoplasm Recurrence, Local/genetics ; Oligonucleotide Array Sequence Analysis ; Prognosis ; Prostatectomy ; Prostatic Neoplasms/surgery ; RNA, Long Noncoding/genetics ; ROC Curve ; Real-Time Polymerase Chain Reaction ; Reproducibility of Results ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Tytuł:
Prognostic Role of Survivin and Macrophage Infiltration Quantified on Protein and mRNA Level in Molecular Subtypes Determined by RT-qPCR of KRT5 , KRT20 , and ERBB2 in Muscle-Invasive Bladder Cancer Treated by Adjuvant Chemotherapy.
Autorzy:
Ecke TH; Department of Urology, HELIOS Hospital Bad Saarow, DE-15526 Bad Sarrow, Germany.; Brandenburg Medical School, DE-14770 Brandenburg, Germany.
Kiani A; Department of Urology, Charité-Universitätsmedizin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, DE-10098 Berlin, Germany.
Schlomm T; Department of Urology, Charité-Universitätsmedizin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, DE-10098 Berlin, Germany.
Friedersdorff F; Department of Urology, Charité-Universitätsmedizin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, DE-10098 Berlin, Germany.
Rabien A; Department of Urology, Charité-Universitätsmedizin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, DE-10098 Berlin, Germany.; Berlin Institute for Urological Research, DE-10098 Berlin, Germany.
Jung K; Department of Urology, Charité-Universitätsmedizin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, DE-10098 Berlin, Germany.; Berlin Institute for Urological Research, DE-10098 Berlin, Germany.
Kilic E; Institute of Pathology, DE-51375 Leverkusen, Germany.
Boström P; Department of Urology, Turku University Hospital, FI-20521 Turku, Finland.
Tervahartiala M; MediCity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku, FI-20520 Turku, Finland.
Taimen P; Institute of Pathology, Turku University Hospital, FI-20521 Turku, Finland.
Gleichenhagen J; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Institute of the Ruhr University Bochum, DE-44789 Bochum, Germany.
Johnen G; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Institute of the Ruhr University Bochum, DE-44789 Bochum, Germany.
Brüning T; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Institute of the Ruhr University Bochum, DE-44789 Bochum, Germany.
Koch S; Brandenburg Medical School, DE-14770 Brandenburg, Germany.; Institute of Pathology, HELIOS Hospital Bad Saarow, DE-15526 Bad Sarrow, Germany.
Roggisch J; Institute of Pathology, HELIOS Hospital Bad Saarow, DE-15526 Bad Sarrow, Germany.
Wirtz RM; STRATIFYER Molecular Pathology GmbH, DE-50935 Cologne, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 08; Vol. 21 (19). Date of Electronic Publication: 2020 Oct 08.
Typ publikacji:
Journal Article
MeSH Terms:
Chemotherapy, Adjuvant/*methods
Keratin-5/*genetics
Macrophages/*immunology
RNA, Messenger/*genetics
Receptor, ErbB-2/*genetics
Survivin/*genetics
Survivin/*metabolism
Urinary Bladder Neoplasms/*drug therapy
Urinary Bladder Neoplasms/*genetics
Aged ; Aged, 80 and over ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Disease-Free Survival ; Female ; Follow-Up Studies ; Humans ; Immunohistochemistry/methods ; Keratin-20/genetics ; Male ; Middle Aged ; Prognosis ; Progression-Free Survival ; Retrospective Studies ; Reverse Transcriptase Polymerase Chain Reaction/methods ; Urinary Bladder Neoplasms/metabolism
Czasopismo naukowe
Tytuł:
Adipose-derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR-25.
Autorzy:
Kuang Y; University Medical Center Goettingen Department of Neurology Goettingen Germany.
Zheng X; University Medical Center Goettingen Department of Neurology Goettingen Germany.
Zhang L; University Medical Center Goettingen Department of Neurology Goettingen Germany.
Ai X; University Medical Center Goettingen Department of Neurology Goettingen Germany.
Venkataramani V; University Medical Center Goettingen Institute for Pathology Goettingen Germany.
Kilic E; Istanbul Medipol University Regenerative and Restorative Medical Research Center Istanbul Turkey.
Hermann DM; Department of Neurology University Hospital Essen University of Duisburg-Essen Essen Germany.
Majid A; Sheffield Institute for Translational Neuroscience University of Sheffield Sheffield UK.
Bähr M; University Medical Center Goettingen Department of Neurology Goettingen Germany.
Doeppner TR; University Medical Center Goettingen Department of Neurology Goettingen Germany.; Istanbul Medipol University Regenerative and Restorative Medical Research Center Istanbul Turkey.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2020 Oct; Vol. 10 (1), pp. e12024. Date of Electronic Publication: 2020 Nov 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Autophagy*
Adipose Tissue/*metabolism
Circulating MicroRNA/*metabolism
Extracellular Vesicles/*metabolism
Mesenchymal Stem Cells/*metabolism
MicroRNAs/*metabolism
Stroke/*metabolism
Adipose Tissue/pathology ; Animals ; Disease Models, Animal ; Extracellular Vesicles/pathology ; Male ; Mesenchymal Stem Cells/pathology ; Mice ; Stroke/pathology
Czasopismo naukowe
Tytuł:
A very short version of the Visual Function Questionnaire (VFQ-3oo7) for use as a routinely applied Patient-Reported Outcome Measure.
Autorzy:
Visser MS; Section of Medical Psychology and Psychotherapy, Department of Psychiatry, Erasmus Medical Centre, Rotterdam, The Netherlands.; Rotterdam Ophthalmic Institute, Rotterdam, The Netherlands.
Timman R; Section of Medical Psychology and Psychotherapy, Department of Psychiatry, Erasmus Medical Centre, Rotterdam, The Netherlands.
Nijmeijer KJ; Rotterdam Ophthalmic Institute, Rotterdam, The Netherlands.; The Rotterdam Eye Hospital, Rotterdam, The Netherlands.
Lemij HG; Rotterdam Ophthalmic Institute, Rotterdam, The Netherlands.; The Rotterdam Eye Hospital, Rotterdam, The Netherlands.
Kilic E; Department of Ophthalmology, Erasmus Medical Centre, Rotterdam, The Netherlands.
Busschbach JJV; Section of Medical Psychology and Psychotherapy, Department of Psychiatry, Erasmus Medical Centre, Rotterdam, The Netherlands.
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Źródło:
Acta ophthalmologica [Acta Ophthalmol] 2020 Sep; Vol. 98 (6), pp. 618-626. Date of Electronic Publication: 2020 Mar 18.
Typ publikacji:
Journal Article; Validation Study
MeSH Terms:
Patient Reported Outcome Measures*
Ophthalmology/*standards
Psychometrics/*methods
Aged ; Eye Diseases/psychology ; Female ; Humans ; Male ; Middle Aged ; Quality of Life ; Reproducibility of Results ; Visual Acuity
Czasopismo naukowe
Tytuł:
Analysis of Correlation between the Seven Important Helicobacter pylori ( H . pylori ) Virulence Factors and Drug Resistance in Patients with Gastritis.
Autorzy:
Oktem-Okullu S; Department of Medical Microbiology, Acibadem Mehmet Ali Aydinlar University, School of Medicine, Atasehir, Istanbul, Turkey.
Cekic-Kipritci Z; Yeditepe University Hospital, Istanbul, Turkey.
Kilic E; Department of Medical Biotechnology, Acibadem Mehmet Ali Aydinlar University, Institute of Health and Science, Atasehir, Istanbul, Turkey.
Seymen N; Department of Biostatistics and Bioinformatics, Acibadem Mehmet Ali Aydinlar University, Institute of Health and Science, Atasehir, Istanbul, Turkey.
Mansur-Ozen N; Department of Medical Biotechnology, Acibadem Mehmet Ali Aydinlar University, Institute of Health and Science, Atasehir, Istanbul, Turkey.
Sezerman U; Department of Biostatistics and Medical Informatics, Acibadem Mehmet Ali Aydinlar University, School of Medicine, Atasehir, Istanbul, Turkey.
Gurol Y; Department of Medical Microbiology, Acibadem Mehmet Ali Aydinlar University, School of Medicine, Atasehir, Istanbul, Turkey.
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Źródło:
Gastroenterology research and practice [Gastroenterol Res Pract] 2020 Aug 29; Vol. 2020, pp. 3956838. Date of Electronic Publication: 2020 Aug 29 (Print Publication: 2020).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Multicenter External Validation of the Liverpool Uveal Melanoma Prognosticator Online: An OOG Collaborative Study.
Autorzy:
Cunha Rola A; Liverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, L7 8TX, UK.
Taktak A; Liverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, L7 8TX, UK.; Department of Medical Physics and Clinical Engineering, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, L69 3GA, UK.
Eleuteri A; Liverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, L7 8TX, UK.; Department of Medical Physics and Clinical Engineering, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, L69 3GA, UK.
Kalirai H; Liverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, L7 8TX, UK.
Heimann H; Liverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, L7 8TX, UK.
Hussain R; Liverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, L7 8TX, UK.
Bonnett LJ; Department of Biostatistics, University of Liverpool, Liverpool, L69 3GL, UK.
Hill CJ; Liverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, L7 8TX, UK.
Traynor M; Liverpool Bio-Innovation Hub Biobank, University of Liverpool, Liverpool, L7 8TX, UK.
Jager MJ; Department of Ophthalmology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands.
Marinkovic M; Department of Ophthalmology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands.
Luyten GPM; Department of Ophthalmology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands.
Dogrusöz M; Department of Ophthalmology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands.
Kilic E; Rotterdam Ocular Melanoma Study Group, Erasmus University Medical Center, Rotterdam, 3008 AE, The Netherlands.
de Klein A; Rotterdam Ocular Melanoma Study Group, Erasmus University Medical Center, Rotterdam, 3008 AE, The Netherlands.
Smit K; Rotterdam Ocular Melanoma Study Group, Erasmus University Medical Center, Rotterdam, 3008 AE, The Netherlands.
van Poppelen NM; Rotterdam Ocular Melanoma Study Group, Erasmus University Medical Center, Rotterdam, 3008 AE, The Netherlands.
Damato BE; Ocular Oncology, Vitreoretinal Diseases & Surgery, University of California, San Francisco, CA 94143, USA.; Oxford Eye Hospital, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, UK.
Afshar A; Ocular Oncology, Vitreoretinal Diseases & Surgery, University of California, San Francisco, CA 94143, USA.
Guthoff RF; Department of Ophthalmology, University of Rostock, D-18057 Rostock, Germany.
Scheef BO; Department of Ophthalmology, University of Rostock, D-18057 Rostock, Germany.
Kakkassery V; Department of Ophthalmology, University of Rostock, D-18057 Rostock, Germany.; Department of Ophthalmology, University of Lübeck, D- 23538 Lübeck, Germany.
Saakyan S; Ocular Oncology Department, Helmholtz Moscow Research Institute of Eye Diseases, 105062 Moscow, Russia.
Tsygankov A; Ocular Oncology Department, Helmholtz Moscow Research Institute of Eye Diseases, 105062 Moscow, Russia.
Mosci C; S.C. Oculistica Oncologica - Ocular Oncology Service, Ente ospedaliero Ospedali Galliera, 16128 Genova, Italy.
Ligorio P; S.C. Oculistica Oncologica - Ocular Oncology Service, Ente ospedaliero Ospedali Galliera, 16128 Genova, Italy.
Viaggi S; DISTAV-Department of Earth, Environment and Life Sciences, University of Genoa, 16132 Genova, Italy.; Laboratory of Human Genetics, IRCCS Istituto G. Gaslini, 16147 Genova, Italy.
Le Guin CHD; Department of Ophthalmology, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.
Bornfeld N; Department of Ophthalmology, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.
Bechrakis NE; Department of Ophthalmology, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.
Coupland SE; Liverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, L7 8TX, UK.; Liverpool Clinical Laboratories, Royal Liverpool University Hospital, Liverpool, L69 3GA, UK.
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Źródło:
Cancers [Cancers (Basel)] 2020 Feb 18; Vol. 12 (2). Date of Electronic Publication: 2020 Feb 18.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Evidence of sulfur mustard exposure in victims of chemical terrorism by detection of urinary β-lyase metabolites.
Autorzy:
Sezigen S; Department of Medical CBRN Defense, University of Health Sciences, Ankara, Turkey.
Eyison RK; Department of Medical CBRN Defense, University of Health Sciences, Ankara, Turkey.
Kilic E; Department of Anesthesia and Reanimation, SehitKamil State Hospital, Gaziantep, Turkey.
Kenar L; Department of Medical CBRN Defense, University of Health Sciences, Ankara, Turkey.
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Źródło:
Clinical toxicology (Philadelphia, Pa.) [Clin Toxicol (Phila)] 2020 Jan; Vol. 58 (1), pp. 36-44. Date of Electronic Publication: 2019 May 10.
Typ publikacji:
Journal Article
MeSH Terms:
Chemical Terrorism*
Chemical Warfare Agents/*toxicity
Lyases/*metabolism
Mustard Gas/*toxicity
Sulfides/*urine
Sulfones/*urine
Adolescent ; Adult ; Female ; Gas Chromatography-Mass Spectrometry ; Humans ; Male ; Middle Aged ; Skin/drug effects ; Skin/pathology ; Syria ; Young Adult
Czasopismo naukowe
Tytuł:
CCL11 Differentially Affects Post-Stroke Brain Injury and Neuroregeneration in Mice Depending on Age.
Autorzy:
Lieschke S; Department of Neurology, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany.
Zechmeister B; Department of Neurology, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany.; Institute of Clinical Chemistry, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany.
Haupt M; Department of Neurology, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany.
Zheng X; Department of Neurology, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany.
Jin F; Department of Hematology, Cancer Center, The First Hospital of Jilin University, 2660 Jiefang Rd., Changchun 130021, China.
Hein K; Department of Neurology, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany.
Weber MS; Department of Neurology, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany.; Institute of Neuropathology, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany.
Hermann DM; Department of Neurology, University of Duisburg-Essen, Hufelandstr. 55, 45147 Essen, Germany.
Bähr M; Department of Neurology, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany.
Kilic E; Department of Physiology, Istanbul Medipol University, Ekinciler Caddesi No. 19, Beykoz/İstanbul TR 34810, Turkey.
Doeppner TR; Department of Neurology, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany.; Department of Physiology, Istanbul Medipol University, Ekinciler Caddesi No. 19, Beykoz/İstanbul TR 34810, Turkey.
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Źródło:
Cells [Cells] 2019 Dec 26; Vol. 9 (1). Date of Electronic Publication: 2019 Dec 26.
Typ publikacji:
Journal Article
MeSH Terms:
Disease Susceptibility*/immunology
Brain Injuries/*etiology
Chemokine CCL11/*genetics
Nerve Regeneration/*genetics
Stroke/*complications
Age Factors ; Animals ; Apoptosis/genetics ; Autophagy/genetics ; Biomarkers ; Brain Infarction/complications ; Brain Injuries/metabolism ; Brain Injuries/pathology ; Brain Ischemia/complications ; Chemokine CCL11/metabolism ; Disease Models, Animal ; Disease Progression ; Immunohistochemistry ; Immunophenotyping ; Male ; Mice ; Signal Transduction
Czasopismo naukowe
Tytuł:
Interaction of melatonin and Bmal1 in the regulation of PI3K/AKT pathway components and cellular survival.
Autorzy:
Beker MC; Regenerative and Restorative Medicine Research Center, Istanbul Medipol University, 34810, Istanbul, Turkey.; Department of Physiology, School of Medicine, Istanbul Medipol University, 34810, Istanbul, Turkey.
Caglayan B; Regenerative and Restorative Medicine Research Center, Istanbul Medipol University, 34810, Istanbul, Turkey.; Department of Medical Biology, International School of Medicine, Istanbul Medipol University, 34810, Istanbul, Turkey.
Caglayan AB; Regenerative and Restorative Medicine Research Center, Istanbul Medipol University, 34810, Istanbul, Turkey.; Department of Physiology, School of Medicine, Istanbul Medipol University, 34810, Istanbul, Turkey.
Kelestemur T; Regenerative and Restorative Medicine Research Center, Istanbul Medipol University, 34810, Istanbul, Turkey.; Department of Physiology, School of Medicine, Istanbul Medipol University, 34810, Istanbul, Turkey.
Yalcin E; Regenerative and Restorative Medicine Research Center, Istanbul Medipol University, 34810, Istanbul, Turkey.; Department of Physiology, School of Medicine, Istanbul Medipol University, 34810, Istanbul, Turkey.
Caglayan A; Regenerative and Restorative Medicine Research Center, Istanbul Medipol University, 34810, Istanbul, Turkey.; Department of Physiology, School of Medicine, Istanbul Medipol University, 34810, Istanbul, Turkey.
Kilic U; Department of Medical Biology, School of Medicine, University of Health Sciences, 34668, Istanbul, Turkey.
Baykal AT; Department of Medical Biochemistry, School of Medicine, Acibadem Mehmet Ali Aydinlar University, 34752, Istanbul, Turkey.
Reiter RJ; Department of Cell Systems and Anatomy, UT Health San Antonio, 78229, Texas, USA.
Kilic E; Regenerative and Restorative Medicine Research Center, Istanbul Medipol University, 34810, Istanbul, Turkey. .; Department of Physiology, School of Medicine, Istanbul Medipol University, 34810, Istanbul, Turkey. .
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Źródło:
Scientific reports [Sci Rep] 2019 Dec 13; Vol. 9 (1), pp. 19082. Date of Electronic Publication: 2019 Dec 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Signal Transduction*/drug effects
ARNTL Transcription Factors/*metabolism
Melatonin/*pharmacology
Phosphatidylinositol 3-Kinases/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Animals ; Brain Ischemia/metabolism ; Brain Ischemia/pathology ; Cell Line ; Cell Survival/drug effects ; Glucose/deficiency ; Male ; Mice, Inbred C57BL ; Neurons/drug effects ; Neurons/metabolism ; Neurons/pathology ; Oxygen ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł:
A Novel Predictor Tool of Biochemical Recurrence after Radical Prostatectomy Based on a Five-MicroRNA Tissue Signature.
Autorzy:
Zhao Z; Department of Urology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany. .; Department of Urology, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China. .
Weickmann S; Department of Urology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany. .
Jung M; Department of Urology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany. .
Lein M; Department of Urology, Sana Medical Center Offenbach, 63069 Offenbach am Main, Germany. .; Berlin Institute for Urologic Research, 10115 Berlin, Germany. .
Kilic E; Institute of Pathology, Hospital Leverkusen, 51375 Leverkusen, Germany. e.kilic@pathologie-leverkusen.de.
Stephan C; Department of Urology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany. .; Berlin Institute for Urologic Research, 10115 Berlin, Germany. .
Erbersdobler A; Institute of Pathology, University of Rostock, 18055 Rostock, Germany. .
Fendler A; Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Cancer Research Program, 13125 Berlin, Germany. .
Jung K; Department of Urology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany. .; Berlin Institute for Urologic Research, 10115 Berlin, Germany. .
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Źródło:
Cancers [Cancers (Basel)] 2019 Oct 21; Vol. 11 (10). Date of Electronic Publication: 2019 Oct 21.
Typ publikacji:
Journal Article
Czasopismo naukowe

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