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Wyszukujesz frazę ""Killer Cells, Natural"" wg kryterium: Temat


Tytuł :
Cryopreservation impairs 3-D migration and cytotoxicity of natural killer cells.
Autorzy :
Mark C; Friedrich-Alexander University Erlangen-Nürnberg, Department of Physics, Erlangen, Germany.
Czerwinski T; Friedrich-Alexander University Erlangen-Nürnberg, Department of Physics, Erlangen, Germany.
Roessner S; Friedrich-Alexander University Erlangen-Nürnberg and University Hospital Erlangen, Department of Dermatology, Erlangen, Germany.; Comprehensive Cancer Center Erlangen-European Metropolitan Area of Nürnberg (CCC ER-EMN), Erlangen, Germany.; Deutsches Zentrum für Immuntherapie (DZI), Erlangen, Germany.
Mainka A; Friedrich-Alexander University Erlangen-Nürnberg, Department of Physics, Erlangen, Germany.
Hörsch F; Friedrich-Alexander University Erlangen-Nürnberg, Department of Physics, Erlangen, Germany.
Heublein L; Friedrich-Alexander University Erlangen-Nürnberg, Department of Physics, Erlangen, Germany.
Winterl A; Friedrich-Alexander University Erlangen-Nürnberg, Department of Physics, Erlangen, Germany.
Sanokowski S; Friedrich-Alexander University Erlangen-Nürnberg, Department of Physics, Erlangen, Germany.
Richter S; Friedrich-Alexander University Erlangen-Nürnberg, Department of Physics, Erlangen, Germany.
Bauer N; Friedrich-Alexander University Erlangen-Nürnberg, Department of Physics, Erlangen, Germany.
Angelini TE; University of Florida, Department of Mechanical and Aerospace Engineering, Gainesville, FL, USA.
Schuler G; Friedrich-Alexander University Erlangen-Nürnberg and University Hospital Erlangen, Department of Dermatology, Erlangen, Germany.; Comprehensive Cancer Center Erlangen-European Metropolitan Area of Nürnberg (CCC ER-EMN), Erlangen, Germany.; Deutsches Zentrum für Immuntherapie (DZI), Erlangen, Germany.
Fabry B; Friedrich-Alexander University Erlangen-Nürnberg, Department of Physics, Erlangen, Germany. .
Voskens CJ; Friedrich-Alexander University Erlangen-Nürnberg and University Hospital Erlangen, Department of Dermatology, Erlangen, Germany.; Comprehensive Cancer Center Erlangen-European Metropolitan Area of Nürnberg (CCC ER-EMN), Erlangen, Germany.; Deutsches Zentrum für Immuntherapie (DZI), Erlangen, Germany.
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Źródło :
Nature communications [Nat Commun] 2020 Oct 16; Vol. 11 (1), pp. 5224. Date of Electronic Publication: 2020 Oct 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Movement*
Killer Cells, Natural/*cytology
Killer Cells, Natural/*immunology
Cell Culture Techniques ; Cell Survival ; Cells, Cultured ; Cryopreservation ; Cytotoxicity, Immunologic ; Humans ; Killer Cells, Natural/chemistry
Czasopismo naukowe
Tytuł :
Prevention of liver metastases through perioperative acute CpG-C immune stimulation.
Autorzy :
Sorski L; Neuroimmunology Research Unit, Sagol School of Neuroscience, The School of Psychological Sciences, Tel Aviv University, 69978, Tel Aviv, Israel.
Melamed R; Neuroimmunology Research Unit, Sagol School of Neuroscience, The School of Psychological Sciences, Tel Aviv University, 69978, Tel Aviv, Israel.
Levi B; Neuroimmunology Research Unit, Sagol School of Neuroscience, The School of Psychological Sciences, Tel Aviv University, 69978, Tel Aviv, Israel.
Matzner P; Neuroimmunology Research Unit, Sagol School of Neuroscience, The School of Psychological Sciences, Tel Aviv University, 69978, Tel Aviv, Israel.
Lavon H; Neuroimmunology Research Unit, Sagol School of Neuroscience, The School of Psychological Sciences, Tel Aviv University, 69978, Tel Aviv, Israel.
Rosenne E; Neuroimmunology Research Unit, Sagol School of Neuroscience, The School of Psychological Sciences, Tel Aviv University, 69978, Tel Aviv, Israel.
Shaashua L; Neuroimmunology Research Unit, Sagol School of Neuroscience, The School of Psychological Sciences, Tel Aviv University, 69978, Tel Aviv, Israel.
Ricon I; Neuroimmunology Research Unit, Sagol School of Neuroscience, The School of Psychological Sciences, Tel Aviv University, 69978, Tel Aviv, Israel.
Sandbank E; Neuroimmunology Research Unit, Sagol School of Neuroscience, The School of Psychological Sciences, Tel Aviv University, 69978, Tel Aviv, Israel.
Benbenishty A; Neuroimmunology Research Unit, Sagol School of Neuroscience, The School of Psychological Sciences, Tel Aviv University, 69978, Tel Aviv, Israel.
Ben-Eliyahu S; Neuroimmunology Research Unit, Sagol School of Neuroscience, The School of Psychological Sciences, Tel Aviv University, 69978, Tel Aviv, Israel. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2020 Oct; Vol. 69 (10), pp. 2021-2031. Date of Electronic Publication: 2020 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Colonic Neoplasms/*prevention & control
Killer Cells, Natural/*drug effects
Liver Neoplasms/*prevention & control
Oligodeoxyribonucleotides/*administration & dosage
Animals ; Apoptosis ; Cell Proliferation ; Colonic Neoplasms/immunology ; Colonic Neoplasms/metabolism ; Colonic Neoplasms/pathology ; Female ; Humans ; Killer Cells, Natural/immunology ; Killer Cells, Natural/pathology ; Liver Neoplasms/immunology ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; Lymphocyte Activation ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Nude ; Perioperative Period ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Cow milk exosomes activate NK cells and γδT cells in human PBMCs in vitro.
Autorzy :
Komine-Aizawa S; Division of Microbiology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan.
Ito S; Nihon University Itabashi Hospital, Tokyo, Japan.
Aizawa S; Department of Animal Science, College of Bioresource Sciences, Nihon University, Kanagawa, Japan.
Namiki T; Nihon University School of Medicine, Tokyo, Japan.
Hayakawa S; Division of Microbiology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan.
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Źródło :
Immunological medicine [Immunol Med] 2020 Dec; Vol. 43 (4), pp. 161-170. Date of Electronic Publication: 2020 Jul 10.
Typ publikacji :
Journal Article
MeSH Terms :
Lymphocyte Activation*
Exosomes/*immunology
Exosomes/*physiology
Killer Cells, Natural/*immunology
Leukocytes, Mononuclear/*immunology
Milk/*cytology
T-Lymphocytes/*immunology
Animals ; Antigens, CD/metabolism ; Antigens, Differentiation, T-Lymphocyte/metabolism ; Cells, Cultured ; Cytokines/metabolism ; Flow Cytometry ; Humans ; Interferon-gamma/metabolism ; Interleukin-12/immunology ; Interleukin-2/immunology ; Killer Cells, Natural/metabolism ; Lectins, C-Type/metabolism ; Leukocytes, Mononuclear/metabolism ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
NK cell alloreactivity in acute myeloid leukemia in the post-transplant cyclophosphamide era.
Autorzy :
Van Elssen CHMJ; Department of Internal Medicine, Division of Hematology, GROW-School of Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
Ciurea SO; Department of Stem Cell Transplantation and Cellular Therapy, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
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Źródło :
American journal of hematology [Am J Hematol] 2020 Dec; Vol. 95 (12), pp. 1590-1598. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Graft vs Leukemia Effect*/drug effects
Graft vs Leukemia Effect*/immunology
Hematopoietic Stem Cell Transplantation*
Leukemia, Myeloid, Acute*/immunology
Leukemia, Myeloid, Acute*/pathology
Leukemia, Myeloid, Acute*/therapy
Cyclophosphamide/*therapeutic use
Killer Cells, Natural/*immunology
T-Lymphocytes/*immunology
Allografts ; Humans ; Killer Cells, Natural/pathology ; Recurrence ; T-Lymphocytes/pathology
Czasopismo naukowe
Tytuł :
IL-6-induced CD39 expression on tumor-infiltrating NK cells predicts poor prognosis in esophageal squamous cell carcinoma.
Autorzy :
Zheng Y; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China.
Li Y; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China.
Tang B; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China.
Zhao Q; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China.
Wang D; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China.
Liu Y; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China.
Guo M; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China.
Zhao S; Department of Thoracic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Qi Y; Department of Thoracic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Zhang Y; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China. .
Huang L; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2020 Nov; Vol. 69 (11), pp. 2371-2380. Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Journal Article
MeSH Terms :
Apyrase/*immunology
Esophageal Neoplasms/*immunology
Esophageal Squamous Cell Carcinoma/*immunology
Interleukin-6/*immunology
Killer Cells, Natural/*immunology
Apyrase/biosynthesis ; Female ; Humans ; Interleukin-6/metabolism ; Killer Cells, Natural/metabolism ; Lymphocytes, Tumor-Infiltrating/immunology ; Lymphocytes, Tumor-Infiltrating/metabolism ; Male ; Prognosis ; Tumor Escape/immunology ; Tumor Microenvironment/immunology
Czasopismo naukowe
Tytuł :
Highly Activated Ex Vivo -expanded Natural Killer Cells in Patients With Solid Tumors in a Phase I/IIa Clinical Study.
Autorzy :
Nagai K; Transfusion and Cell Therapy Unit, Nagasaki University Hospital, Nagasaki, Japan .
Harada Y; R&D Laboratory for Innovative Biotherapeutics, Kyushu University Graduate School of Pharmaceutical Science, Fukuoka, Japan.
Harada H; Transfusion and Cell Therapy Unit, Nagasaki University Hospital, Nagasaki, Japan.
Yanagihara K; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan.
Yonemitsu Y; R&D Laboratory for Innovative Biotherapeutics, Kyushu University Graduate School of Pharmaceutical Science, Fukuoka, Japan.
Miyazaki Y; Transfusion and Cell Therapy Unit, Nagasaki University Hospital, Nagasaki, Japan.; Department of Hematology, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan.
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Źródło :
Anticancer research [Anticancer Res] 2020 Oct; Vol. 40 (10), pp. 5687-5700.
Typ publikacji :
Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article
MeSH Terms :
Cell- and Tissue-Based Therapy*
Killer Cells, Natural/*transplantation
Neoplasms/*therapy
Transplantation, Autologous/*methods
Adult ; Aged ; Aged, 80 and over ; Cell Proliferation/genetics ; Dose-Response Relationship, Immunologic ; Female ; Humans ; Killer Cells, Natural/immunology ; Male ; Maximum Tolerated Dose ; Middle Aged ; Neoplasms/immunology ; Neoplasms/pathology
Czasopismo naukowe
Tytuł :
[Establishment of A Novel Method to Activate and Expand Human NK Cells Ex Vivo].
Autorzy :
Qian KC; Shenzhen Cell Technology Co., Ltd, Shenzhen 518055, Guangdong Province, China.
Ge SH; Shenzhen Cell Technology Co., Ltd, Shenzhen 518055, Guangdong Province, China.
Jie FJ; Shenzhen Cell Technology Co., Ltd, Shenzhen 518055, Guangdong Province, China.
Guo ZK; Shenzhen Cell Technology Co., Ltd, Shenzhen 518055, Guangdong Province, China,E-mail: .
Zhang DP; Shenzhen Cell Technology Co., Ltd, Shenzhen 518055, Guangdong Province, China,E-mail: .
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Źródło :
Zhongguo shi yan xue ye xue za zhi [Zhongguo Shi Yan Xue Ye Xue Za Zhi] 2020 Oct; Vol. 28 (5), pp. 1769-1773.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Culture Techniques*
Killer Cells, Natural*
Flow Cytometry ; Humans ; K562 Cells
Czasopismo naukowe
Tytuł :
Synaptic secretion from human natural killer cells is diverse and includes supramolecular attack particles.
Autorzy :
Ambrose AR; The Lydia Becker Institute of Immunology and Inflammation, University of Manchester, M13 9NT Manchester, United Kingdom.
Hazime KS; The Lydia Becker Institute of Immunology and Inflammation, University of Manchester, M13 9NT Manchester, United Kingdom.
Worboys JD; The Lydia Becker Institute of Immunology and Inflammation, University of Manchester, M13 9NT Manchester, United Kingdom.
Niembro-Vivanco O; The Lydia Becker Institute of Immunology and Inflammation, University of Manchester, M13 9NT Manchester, United Kingdom.
Davis DM; The Lydia Becker Institute of Immunology and Inflammation, University of Manchester, M13 9NT Manchester, United Kingdom .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 22; Vol. 117 (38), pp. 23717-23720. Date of Electronic Publication: 2020 Sep 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Killer Cells, Natural*/chemistry
Killer Cells, Natural*/immunology
Killer Cells, Natural*/metabolism
Synapses*/chemistry
Synapses*/immunology
Synapses*/metabolism
Granzymes/metabolism ; Humans ; Perforin/metabolism ; T-Lymphocytes, Cytotoxic/chemistry ; T-Lymphocytes, Cytotoxic/immunology ; T-Lymphocytes, Cytotoxic/metabolism ; Thrombospondin 1/metabolism
Czasopismo naukowe
Tytuł :
COVID-19 pneumonia: CD8 T and NK cells are decreased in number but compensatory increased in cytotoxic potential.
Autorzy :
Jiang Y; Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Wei X; Department of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei 230032, China.
Guan J; Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Qin S; Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Wang Z; Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Lu H; Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Qian J; Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Wu L; Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Chen Y; Department of Infectious Diseases, The First Affiliated Hospital of Wenzhou, Medical University, Wenzhou 325000, China.
Chen Y; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China. Electronic address: .
Lin X; Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China. Electronic address: .
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Źródło :
Clinical immunology (Orlando, Fla.) [Clin Immunol] 2020 Sep; Vol. 218, pp. 108516. Date of Electronic Publication: 2020 Jun 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Betacoronavirus/*pathogenicity
Coronavirus Infections/*diagnosis
Granzymes/*genetics
Killer Cells, Natural/*immunology
Perforin/*genetics
Pneumonia, Viral/*diagnosis
T-Lymphocytes, Cytotoxic/*immunology
Aged ; Aged, 80 and over ; Betacoronavirus/immunology ; Biomarkers/blood ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/pathology ; CD4-Positive T-Lymphocytes/virology ; Case-Control Studies ; China ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/blood ; Coronavirus Infections/immunology ; Coronavirus Infections/pathology ; Disease Progression ; Female ; Gene Expression ; Granzymes/blood ; Granzymes/immunology ; Humans ; Killer Cells, Natural/pathology ; Killer Cells, Natural/virology ; Lymphocyte Activation ; Lymphocyte Count ; Male ; Middle Aged ; Pandemics ; Perforin/blood ; Perforin/immunology ; Pneumonia, Viral/blood ; Pneumonia, Viral/immunology ; Pneumonia, Viral/pathology ; Prognosis ; ROC Curve ; Severity of Illness Index ; T-Lymphocytes, Cytotoxic/pathology ; T-Lymphocytes, Cytotoxic/virology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Natural killer cell phenotype is altered in HIV-exposed seronegative women.
Autorzy :
Zhao NQ; Department of Medicine, Division of Infection Diseases and Geographic Medicine, Stanford University, Stanford, CA, United States of America.; Immunology Program, Stanford University, Stanford, CA, United States of America.
Vendrame E; Department of Medicine, Division of Infection Diseases and Geographic Medicine, Stanford University, Stanford, CA, United States of America.
Ferreira AM; Department of Statistics, Stanford University, Stanford, CA, United States of America.
Seiler C; Department of Statistics, Stanford University, Stanford, CA, United States of America.
Ranganath T; Department of Medicine, Division of Infection Diseases and Geographic Medicine, Stanford University, Stanford, CA, United States of America.
Alary M; Centre de Recherche du CHU de Québec-Université Laval, Québec, Canada, Département de Médecine Sociale et Préventive, Université Laval, Québec, Canada, Institut National de Santé Publique du Québec, Québec, Canada.
Labbé AC; Département de Microbiologie, Infectiologie et Immunologie de l'Université de Montréal, Montréal, Canada, Service de maladies infectieuses et microbiologie, Hôpital Maisonneuve-Rosemont, Montréal, Canada.
Guédou F; Dispensaire IST, Cotonou, Bénin.
Poudrier J; Laboratoire d'Immunogénétique, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Canada, Département de Microbiologie, Infectiologie et Immunologie de l'Université de Montréal, Montréal, Canada.
Holmes S; Department of Statistics, Stanford University, Stanford, CA, United States of America.
Roger M; Laboratoire d'Immunogénétique, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Canada, Département de Microbiologie, Infectiologie et Immunologie de l'Université de Montréal, Montréal, Canada.
Blish CA; Department of Medicine, Division of Infection Diseases and Geographic Medicine, Stanford University, Stanford, CA, United States of America.; Immunology Program, Stanford University, Stanford, CA, United States of America.; Chan Zuckerberg Biohub, San Francisco, CA, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Sep 01; Vol. 15 (9), pp. e0238347. Date of Electronic Publication: 2020 Sep 01 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
HIV Infections/*pathology
Killer Cells, Natural/*metabolism
Adult ; Antibody-Dependent Cell Cytotoxicity/immunology ; Antigens, Differentiation, Myelomonocytic/metabolism ; Female ; GPI-Linked Proteins/genetics ; GPI-Linked Proteins/metabolism ; Genotype ; HIV Infections/immunology ; Humans ; Killer Cells, Natural/cytology ; Killer Cells, Natural/immunology ; Lectins/metabolism ; Linear Models ; Natural Cytotoxicity Triggering Receptor 3/metabolism ; Phenotype ; Receptors, IgG/genetics ; Receptors, IgG/metabolism ; Sex Workers
Czasopismo naukowe
Tytuł :
The cancer-natural killer cell immunity cycle.
Autorzy :
Huntington ND; Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia. .; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia. .; oNKo-Innate Pty Ltd, Moonee Ponds, Victoria, Australia. .
Cursons J; Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia. .; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia. .; oNKo-Innate Pty Ltd, Moonee Ponds, Victoria, Australia. .
Rautela J; Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.; oNKo-Innate Pty Ltd, Moonee Ponds, Victoria, Australia.
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Źródło :
Nature reviews. Cancer [Nat Rev Cancer] 2020 Aug; Vol. 20 (8), pp. 437-454. Date of Electronic Publication: 2020 Jun 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antineoplastic Agents/*immunology
Antineoplastic Agents/*therapeutic use
Killer Cells, Natural/*immunology
Neoplasms/*drug therapy
Neoplasms/*immunology
Cell Communication/genetics ; Cell Communication/immunology ; Cell Communication/physiology ; Cell Cycle/immunology ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Genes, cdc/drug effects ; Genes, cdc/genetics ; Genes, cdc/immunology ; Genes, cdc/physiology ; Humans ; Immunologic Surveillance/immunology ; Immunotherapy/methods ; Killer Cells, Natural/drug effects ; Killer Cells, Natural/physiology ; Neoplastic Processes ; Prognosis
Czasopismo naukowe
Tytuł :
Energy metabolism and cell motility defect in NK-cells from patients with hepatocellular carcinoma.
Autorzy :
Zecca A; Laboratory of Viral Immunopathology, Unit of Infectious Diseases and Hepatology, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Barili V; Department of Medicine and Surgery, University of Parma, Via Gramsci 14, 43126, Parma, Italy.
Canetti D; Laboratory of Viral Immunopathology, Unit of Infectious Diseases and Hepatology, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Regina V; Laboratory of Viral Immunopathology, Unit of Infectious Diseases and Hepatology, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Olivani A; Laboratory of Viral Immunopathology, Unit of Infectious Diseases and Hepatology, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Carone C; Toxicology and Advanced Diagnostics, Ospedale S. Agostino-Estense, Modena, Italy.
Capizzuto V; Department of Medicine and Surgery, University of Parma, Via Gramsci 14, 43126, Parma, Italy.
Zerbato B; Department of Medicine and Surgery, University of Parma, Via Gramsci 14, 43126, Parma, Italy.
Trenti T; Toxicology and Advanced Diagnostics, Ospedale S. Agostino-Estense, Modena, Italy.
Dalla Valle R; Department of Medicine and Surgery, University of Parma, Via Gramsci 14, 43126, Parma, Italy.
Ferrari C; Department of Medicine and Surgery, University of Parma, Via Gramsci 14, 43126, Parma, Italy.
Cariani E; Toxicology and Advanced Diagnostics, Ospedale S. Agostino-Estense, Modena, Italy.
Missale G; Department of Medicine and Surgery, University of Parma, Via Gramsci 14, 43126, Parma, Italy. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2020 Aug; Vol. 69 (8), pp. 1589-1603. Date of Electronic Publication: 2020 Apr 19.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Movement*
Energy Metabolism*
Carcinoma, Hepatocellular/*immunology
Carcinoma, Hepatocellular/*pathology
Hepatitis C/*complications
Killer Cells, Natural/*pathology
Liver Cirrhosis/*pathology
Liver Neoplasms/*pathology
Aged ; Carcinoma, Hepatocellular/virology ; Case-Control Studies ; Cytokines/metabolism ; Cytotoxicity, Immunologic/immunology ; Female ; Follow-Up Studies ; Hepacivirus/isolation & purification ; Hepatitis C/virology ; Humans ; Killer Cells, Natural/immunology ; Killer Cells, Natural/virology ; Liver Cirrhosis/immunology ; Liver Cirrhosis/virology ; Liver Neoplasms/immunology ; Liver Neoplasms/virology ; Male ; Prognosis ; Transforming Growth Factor beta/metabolism ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Imlifidase Inhibits HLA Antibody-mediated NK Cell Activation and Antibody-dependent Cell-mediated Cytotoxicity (ADCC) In Vitro.
Autorzy :
Ge S; Transplant Immunology Laboratory, Department of Medicine, Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Chu M; Transplant Immunology Laboratory, Department of Medicine, Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Choi J; Department of Medicine, Division of Nephrology, Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Louie S; Department of Medicine, Division of Nephrology, Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Vo A; Department of Medicine, Division of Nephrology, Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Jordan SC; Department of Medicine, Division of Nephrology, Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Toyoda M; Transplant Immunology Laboratory, Department of Medicine, Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
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Źródło :
Transplantation [Transplantation] 2020 Aug; Vol. 104 (8), pp. 1574-1579.
Typ publikacji :
Journal Article
MeSH Terms :
Antibody-Dependent Cell Cytotoxicity/*drug effects
Bacterial Proteins/*therapeutic use
Immunosuppressive Agents/*pharmacology
Killer Cells, Natural/*drug effects
Organ Transplantation/*adverse effects
Adult ; Antibody-Dependent Cell Cytotoxicity/immunology ; Bacterial Proteins/pharmacology ; Biological Assay ; Cells, Cultured ; Complement Activation/drug effects ; Desensitization, Immunologic/methods ; HLA Antigens/immunology ; Humans ; Immunosuppressive Agents/therapeutic use ; Interferon-gamma/immunology ; Interferon-gamma/metabolism ; Isoantibodies/immunology ; Isoantibodies/metabolism ; Killer Cells, Natural/immunology ; Killer Cells, Natural/metabolism ; Leukocytes, Mononuclear ; Primary Cell Culture ; Receptors, IgG/immunology ; Receptors, IgG/metabolism ; Transplantation, Homologous/adverse effects
Czasopismo naukowe
Tytuł :
NK cells: A double edge sword against SARS-CoV-2.
Autorzy :
Masselli E; Department of Medicine and Surgery, Anatomy Unit, University of Parma, Via Gramsci 14, 43126, Parma, Italy; University Hospital of Parma, AOU-PR, Via Gramsci 14, 43126, Parma, Italy.
Vaccarezza M; School of Pharmacy and Biomedical Sciences, Faculty of Health Sciences, Curtin University, Bentley, Perth, WA, 6102, Australia.
Carubbi C; Department of Medicine and Surgery, Anatomy Unit, University of Parma, Via Gramsci 14, 43126, Parma, Italy.
Pozzi G; Department of Medicine and Surgery, Anatomy Unit, University of Parma, Via Gramsci 14, 43126, Parma, Italy.
Presta V; Department of Medicine and Surgery, Anatomy Unit, University of Parma, Via Gramsci 14, 43126, Parma, Italy.
Mirandola P; Department of Medicine and Surgery, Anatomy Unit, University of Parma, Via Gramsci 14, 43126, Parma, Italy. Electronic address: .
Vitale M; Department of Medicine and Surgery, Anatomy Unit, University of Parma, Via Gramsci 14, 43126, Parma, Italy; University Hospital of Parma, AOU-PR, Via Gramsci 14, 43126, Parma, Italy. Electronic address: .
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Źródło :
Advances in biological regulation [Adv Biol Regul] 2020 Aug; Vol. 77, pp. 100737. Date of Electronic Publication: 2020 Jun 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Pandemics*
Betacoronavirus/*pathogenicity
Coronavirus Infections/*epidemiology
Host-Pathogen Interactions/*immunology
Killer Cells, Natural/*immunology
Pneumonia, Viral/*epidemiology
Respiratory Insufficiency/*epidemiology
Acute Disease ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/immunology ; Gene Expression Regulation ; Immunity, Innate ; Interferon-gamma/genetics ; Interferon-gamma/immunology ; Interleukins/genetics ; Interleukins/immunology ; Killer Cells, Natural/pathology ; Killer Cells, Natural/virology ; Lung/immunology ; Lung/pathology ; Lung/virology ; Lymphocyte Activation ; Lysosomal-Associated Membrane Protein 1/genetics ; Lysosomal-Associated Membrane Protein 1/immunology ; NK Cell Lectin-Like Receptor Subfamily C/genetics ; NK Cell Lectin-Like Receptor Subfamily C/immunology ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/immunology ; Respiratory Insufficiency/complications ; Respiratory Insufficiency/diagnosis ; Respiratory Insufficiency/immunology ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/immunology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Docetaxel suppresses immunotherapy efficacy of natural killer cells toward castration-resistant prostate cancer cells via altering androgen receptor-lectin-like transcript 1 signals.
Autorzy :
Tang M; Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Gao S; Department of Urology, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, Jiangsu, China.
Zhang L; Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Liu B; Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Li J; Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Wang Z; Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Zhang W; Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
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Źródło :
The Prostate [Prostate] 2020 Jul; Vol. 80 (10), pp. 742-752. Date of Electronic Publication: 2020 May 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Docetaxel/*adverse effects
Killer Cells, Natural/*drug effects
Lectins, C-Type/*immunology
Prostatic Neoplasms, Castration-Resistant/*immunology
Prostatic Neoplasms, Castration-Resistant/*therapy
Receptors, Androgen/*immunology
Receptors, Cell Surface/*immunology
Androgen Receptor Antagonists/pharmacology ; Antibodies, Monoclonal/immunology ; Antibodies, Monoclonal/pharmacology ; Antineoplastic Agents/adverse effects ; Antineoplastic Agents/therapeutic use ; Cell Line, Tumor ; Coculture Techniques ; Combined Modality Therapy ; Curcumin/analogs & derivatives ; Curcumin/pharmacology ; Docetaxel/therapeutic use ; HEK293 Cells ; Humans ; Immunotherapy, Adoptive/methods ; Killer Cells, Natural/immunology ; Killer Cells, Natural/transplantation ; Lectins, C-Type/antagonists & inhibitors ; Lectins, C-Type/biosynthesis ; Male ; Prostatic Neoplasms, Castration-Resistant/drug therapy ; Receptors, Androgen/biosynthesis ; Receptors, Androgen/genetics ; Receptors, Cell Surface/antagonists & inhibitors ; Receptors, Cell Surface/biosynthesis ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
THE CONTENT OF NK CELLS AND THEIR SUBTYPES IN THE CASE OF DRUG-INDUCED JAW OSTEONECROSIS.
Autorzy :
Ivanyushko T; Sechenov First Moscow State Medical University, Moscow, Russian Federation.
Polyakov K; Sechenov First Moscow State Medical University, Moscow, Russian Federation.
Usatov D; Sechenov First Moscow State Medical University, Moscow, Russian Federation.
Petruk P; Sechenov First Moscow State Medical University, Moscow, Russian Federation.
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Źródło :
Georgian medical news [Georgian Med News] 2020 Sep (306), pp. 41-46.
Typ publikacji :
Journal Article
MeSH Terms :
Bisphosphonate-Associated Osteonecrosis of the Jaw*/immunology
Bone Density Conservation Agents*
Jaw Diseases*
Killer Cells, Natural*
Lymphocytes*
Aged ; Diphosphonates/adverse effects ; Humans ; Middle Aged
Czasopismo naukowe
Tytuł :
Natural Killer Cell Dysfunction and Its Role in COVID-19.
Autorzy :
van Eeden C; Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Khan L; Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Osman MS; Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Cohen Tervaert JW; Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2R3, Canada.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Sep 01; Vol. 21 (17). Date of Electronic Publication: 2020 Sep 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Immunity, Innate*
Betacoronavirus/*immunology
Coronavirus Infections/*immunology
Coronavirus Infections/*virology
Disease Susceptibility/*immunology
Host-Pathogen Interactions/*immunology
Killer Cells, Natural/*immunology
Pneumonia, Viral/*immunology
Pneumonia, Viral/*virology
Autoimmunity ; Coronavirus Infections/metabolism ; Humans ; Immunomodulation ; Killer Cells, Natural/metabolism ; Pandemics ; Pneumonia, Viral/metabolism
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Lymphocyte subsets with the lowest decline at baseline and the slow lowest rise during recovery in COVID-19 critical illness patients with diabetes mellitus.
Autorzy :
Liu D; Department of Internal Medicine, The Public and Health Clinic Centre of Chengdu, Chengdu, China. Electronic address: .
Lan L; Department of Internal Medicine, The Public and Health Clinic Centre of Chengdu, Chengdu, China.
Luo D; Department of Science and Education, The Public and Health Clinic Centre of Chengdu, Chengdu, China.
Zhao B; Department of Internal Medicine, The Public and Health Clinic Centre of Chengdu, Chengdu, China.
Wei G; Department of Surgical Second Ward, The Public and Health Clinic Centre of Chengdu, Chengdu, China.
He Y; Department of Internal Medicine, The Public and Health Clinic Centre of Chengdu, Chengdu, China.
Zhang R; Department of Vice Headmaster's Office, The Public and Health Clinic Centre of Chengdu, Chengdu, China. Electronic address: .
Liu Y; Department of Internal Medicine, The Public and Health Clinic Centre of Chengdu, Chengdu, China. Electronic address: .
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Źródło :
Diabetes research and clinical practice [Diabetes Res Clin Pract] 2020 Sep; Vol. 167, pp. 108341. Date of Electronic Publication: 2020 Jul 22.
Typ publikacji :
Journal Article
MeSH Terms :
B-Lymphocytes*
CD4-Positive T-Lymphocytes*
CD8-Positive T-Lymphocytes*
Killer Cells, Natural*
T-Lymphocyte Subsets*
Coronavirus Infections/*blood
Diabetes Complications/*blood
Diabetes Mellitus/*metabolism
Pneumonia, Viral/*blood
Adult ; Aged ; Antigens, CD19 ; Betacoronavirus ; CD3 Complex ; CD4 Lymphocyte Count ; CD56 Antigen ; Comorbidity ; Coronavirus Infections/complications ; Critical Illness ; Disease Progression ; Female ; Humans ; Length of Stay ; Lymphocyte Count ; Lymphocyte Subsets ; Lymphocytes ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/complications ; Prognosis ; Retrospective Studies ; Severity of Illness Index
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Make killers sweeter: targeting metabolic checkpoints of NK cells.
Autorzy :
Wei H; Hefei National Laboratory for Physical Sciences at Microscale, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China. .; Institute of Immunology, University of Science and Technology of China, Hefei, Anhui, China. .
Fu B; Hefei National Laboratory for Physical Sciences at Microscale, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China. .; Institute of Immunology, University of Science and Technology of China, Hefei, Anhui, China. .
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Źródło :
Nature immunology [Nat Immunol] 2020 Sep; Vol. 21 (9), pp. 970-971.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Immunity, Innate*
Killer Cells, Natural*
Czasopismo naukowe
Tytuł :
CAR-NK Therapy: Translating a Novel Immunotherapy Treatment to Solid Organ Transplantation.
Autorzy :
Loh K; MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital and the Center for Translational Transplant Medicine, Georgetown University Medical Center, Washington, DC.; Children's National Hospital, Washington, DC.
Khan K; MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital and the Center for Translational Transplant Medicine, Georgetown University Medical Center, Washington, DC.
Kroemer A; MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital and the Center for Translational Transplant Medicine, Georgetown University Medical Center, Washington, DC.
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Źródło :
Transplantation [Transplantation] 2020 Aug; Vol. 104 (8), pp. 1523-1524.
Typ publikacji :
Journal Article
MeSH Terms :
Graft Rejection/*therapy
Immunotherapy, Adoptive/*methods
Killer Cells, Natural/*transplantation
Organ Transplantation/*adverse effects
Receptors, Chimeric Antigen/*immunology
Allografts/immunology ; Graft Rejection/immunology ; HLA Antigens/immunology ; Histocompatibility Testing ; Humans ; Immunosuppressive Agents/adverse effects ; Killer Cells, Natural/immunology ; Transplantation Tolerance/immunology
Czasopismo naukowe

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