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Tytuł:
IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts.
Autorzy:
Van den Eynde A; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium. .
Gehrcken L; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
Verhezen T; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
Lau HW; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
Hermans C; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
Lambrechts H; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
Flieswasser T; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
Quatannens D; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
Roex G; Laboratory of Experimental Hematology (LEH), Vaccine and Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Edegem, Belgium.
Zwaenepoel K; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.; Department of Pathology, Antwerp University Hospital, Edegem, Belgium.
Marcq E; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.; Lab of Dendritic Cell Biology and Cancer Immunotherapy, VIB Center for Inflammation Research, Brussels, Belgium.; Brussels Center for Immunology, Vrije Universiteit Brussel, Brussels, Belgium.
Joye P; Molecular Imaging Center Antwerp (MICA), University of Antwerp, Wilrijk, Belgium.
Cardenas De La Hoz E; Industrial Vision Lab (InViLab), University of Antwerp, Antwerp, Belgium.
Deben C; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
Gasparini A; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.; Iridium Netwerk, Radiation Oncology, Antwerp, Belgium.
Montay-Gruel P; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.; Iridium Netwerk, Radiation Oncology, Antwerp, Belgium.
Le Compte M; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
Lion E; Laboratory of Experimental Hematology (LEH), Vaccine and Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Edegem, Belgium.; Center for Cell Therapy and Regenerative Medicine (CCRG), Antwerp University Hospital, Edegem, Belgium.
Lardon F; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
Van Laere S; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.; Department of Pathology, Antwerp University Hospital, Edegem, Belgium.
Siozopoulou V; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.; University Hospital Saint-Luc, University of Louvain, Brussels, Belgium.
Campillo-Davo D; Laboratory of Experimental Hematology (LEH), Vaccine and Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Edegem, Belgium.
De Waele J; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
Pauwels P; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.; Department of Pathology, Antwerp University Hospital, Edegem, Belgium.
Jacobs J; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
Smits E; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
Van Audenaerde JRM; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
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Źródło:
Journal of hematology & oncology [J Hematol Oncol] 2024 Feb 09; Vol. 17 (1), pp. 8. Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:
Journal Article
MeSH Terms:
Cancer-Associated Fibroblasts*
Lymphoma*/metabolism
Humans ; Animals ; Mice ; Cytotoxicity, Immunologic ; Interleukin-15/metabolism ; Cell Line, Tumor ; Killer Cells, Natural ; Immunotherapy, Adoptive/methods ; Cytokines/metabolism ; CD27 Ligand
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Understanding Type 3 Innate Lymphoid Cells and Crosstalk with the Microbiota: A Skin Connection.
Autorzy:
To TT; Division of Dermatology, Department of Medicine, University of California (UCLA), Los Angeles, CA 90095, USA.
Oparaugo NC; Division of Dermatology, Department of Medicine, University of California (UCLA), Los Angeles, CA 90095, USA.
Kheshvadjian AR; Division of Dermatology, Department of Medicine, University of California (UCLA), Los Angeles, CA 90095, USA.
Nelson AM; Department of Dermatology, Penn State University College of Medicine, Hershey, PA 17033, USA.
Agak GW; Division of Dermatology, Department of Medicine, University of California (UCLA), Los Angeles, CA 90095, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 07; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Lymphocytes*
Microbiota*
Immunity, Innate ; Killer Cells, Natural ; Skin ; Cytokines
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Integrated Analysis of Single-Cell and Bulk RNA Sequencing Data Reveals Memory-like NK Cell Subset Associated with Mycobacterium tuberculosis Latency.
Autorzy:
Shekarkar Azgomi M; Central Laboratory of Advanced Diagnosis and Biomedical Research (CLADIBIOR), Azienda Ospedaliera Universitaria Policlinico (AOUP) Paolo Giaccone, University of Palermo, 90127 Palermo, Italy.; Department of Biomedicine, Neurosciences and Advanced Diagnostic (BND), University of Palermo, 90127 Palermo, Italy.
Badami GD; Central Laboratory of Advanced Diagnosis and Biomedical Research (CLADIBIOR), Azienda Ospedaliera Universitaria Policlinico (AOUP) Paolo Giaccone, University of Palermo, 90127 Palermo, Italy.
Lo Pizzo M; Central Laboratory of Advanced Diagnosis and Biomedical Research (CLADIBIOR), Azienda Ospedaliera Universitaria Policlinico (AOUP) Paolo Giaccone, University of Palermo, 90127 Palermo, Italy.
Tamburini B; Central Laboratory of Advanced Diagnosis and Biomedical Research (CLADIBIOR), Azienda Ospedaliera Universitaria Policlinico (AOUP) Paolo Giaccone, University of Palermo, 90127 Palermo, Italy.; Department of Health Promotion, Mother and Childcare, Internal Medicine and Medical Specialties, University of Palermo, 90129 Palermo, Italy.
Dieli C; Central Laboratory of Advanced Diagnosis and Biomedical Research (CLADIBIOR), Azienda Ospedaliera Universitaria Policlinico (AOUP) Paolo Giaccone, University of Palermo, 90127 Palermo, Italy.
La Manna MP; Central Laboratory of Advanced Diagnosis and Biomedical Research (CLADIBIOR), Azienda Ospedaliera Universitaria Policlinico (AOUP) Paolo Giaccone, University of Palermo, 90127 Palermo, Italy.; Department of Biomedicine, Neurosciences and Advanced Diagnostic (BND), University of Palermo, 90127 Palermo, Italy.
Dieli F; Central Laboratory of Advanced Diagnosis and Biomedical Research (CLADIBIOR), Azienda Ospedaliera Universitaria Policlinico (AOUP) Paolo Giaccone, University of Palermo, 90127 Palermo, Italy.; Department of Biomedicine, Neurosciences and Advanced Diagnostic (BND), University of Palermo, 90127 Palermo, Italy.
Caccamo N; Central Laboratory of Advanced Diagnosis and Biomedical Research (CLADIBIOR), Azienda Ospedaliera Universitaria Policlinico (AOUP) Paolo Giaccone, University of Palermo, 90127 Palermo, Italy.; Department of Biomedicine, Neurosciences and Advanced Diagnostic (BND), University of Palermo, 90127 Palermo, Italy.
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Źródło:
Cells [Cells] 2024 Feb 06; Vol. 13 (4). Date of Electronic Publication: 2024 Feb 06.
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*
Tuberculosis*
Humans ; RNA ; Immunity, Innate ; Killer Cells, Natural ; Sequence Analysis, RNA ; NK Cell Lectin-Like Receptor Subfamily C
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Nodal peripheral T-cell lymphomas in the new classification systems.
Autorzy:
Amador C; Department of Pathology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Chan WC; Department of Pathology, City of Hope National Medical Center, Duarte, CA 91010, USA.
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Źródło:
Cancer biology & medicine [Cancer Biol Med] 2024 Feb 05; Vol. 20 (12).
Typ publikacji:
Editorial
MeSH Terms:
Lymphoma, T-Cell, Peripheral*/pathology
Humans ; Killer Cells, Natural
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Outlining the skin-homing and circulating CLA NK cells in patients with severe atopic dermatitis.
Autorzy:
de Lima JF; Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Av. Dr. Eneas de Carvalho Aguiar, 255, 3o. andar ICHC, Sala 3016, Cerqueira Cesar, Sao Paulo, SP, 05403-002, Brazil.
Teixeira FME; Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Av. Dr. Eneas de Carvalho Aguiar, 255, 3o. andar ICHC, Sala 3016, Cerqueira Cesar, Sao Paulo, SP, 05403-002, Brazil.
Ramos YÁL; Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Av. Dr. Eneas de Carvalho Aguiar, 255, 3o. andar ICHC, Sala 3016, Cerqueira Cesar, Sao Paulo, SP, 05403-002, Brazil.
de Carvalho GC; Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Av. Dr. Eneas de Carvalho Aguiar, 255, 3o. andar ICHC, Sala 3016, Cerqueira Cesar, Sao Paulo, SP, 05403-002, Brazil.
Castelo Branco ACC; Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Av. Dr. Eneas de Carvalho Aguiar, 255, 3o. andar ICHC, Sala 3016, Cerqueira Cesar, Sao Paulo, SP, 05403-002, Brazil.
Pereira NV; Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Av. Dr. Eneas de Carvalho Aguiar, 255, 3o. andar ICHC, Sala 3016, Cerqueira Cesar, Sao Paulo, SP, 05403-002, Brazil.
Sotto MN; Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Av. Dr. Eneas de Carvalho Aguiar, 255, 3o. andar ICHC, Sala 3016, Cerqueira Cesar, Sao Paulo, SP, 05403-002, Brazil.
Aoki V; Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Av. Dr. Eneas de Carvalho Aguiar, 255, 3o. andar ICHC, Sala 3016, Cerqueira Cesar, Sao Paulo, SP, 05403-002, Brazil.
Sato MN; Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Av. Dr. Eneas de Carvalho Aguiar, 255, 3o. andar ICHC, Sala 3016, Cerqueira Cesar, Sao Paulo, SP, 05403-002, Brazil.
Orfali RL; Department of Dermatology, Laboratory of Dermatology and Immunodeficiencies (LIM-56), Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Av. Dr. Eneas de Carvalho Aguiar, 255, 3o. andar ICHC, Sala 3016, Cerqueira Cesar, Sao Paulo, SP, 05403-002, Brazil. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 01; Vol. 14 (1), pp. 2663. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Dermatitis, Atopic*
Adult ; Humans ; Immunity, Innate ; Antigens, Differentiation, T-Lymphocyte/metabolism ; Killer Cells, Natural/metabolism ; Enterotoxins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Natural Killer Cells, as the Rising Point in Tissues, Are Forgotten in the Kidney.
Autorzy:
Ma K; Department of Nephrology, The First Affiliated Hospital of Jinan University, Guangzhou 510000, China.
Zheng ZR; Department of Nephrology, The First Affiliated Hospital of Jinan University, Guangzhou 510000, China.
Meng Y; Department of Nephrology, The First Affiliated Hospital of Jinan University, Guangzhou 510000, China.; Department of Nephrology, The Fifth Affiliated Hospital of Jinan University, Heyuan 570000, China.
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Źródło:
Biomolecules [Biomolecules] 2023 Apr 26; Vol. 13 (5). Date of Electronic Publication: 2023 Apr 26.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunity, Innate*
Killer Cells, Natural*
Kidney ; Liver
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
KLRF1, a novel marker of CD56 NK cells, predicts improved survival for patients with locally advanced bladder cancer.
Autorzy:
Mukherjee N; Department of Urology, University of Texas Health San Antonio (UTHSA), San Antonio, Texas, United States.
Ji N; Department of Urology, University of Texas Health San Antonio (UTHSA), San Antonio, Texas, United States.
Tan X; Department of Molecular Medicine, University of Texas Health San Antonio (UTHSA), San Antonio, Texas, United States.
Chen CL; Department of Molecular Medicine, University of Texas Health San Antonio (UTHSA), San Antonio, Texas, United States.
Noel ODV; Department of Urology, University of Texas Health San Antonio (UTHSA), San Antonio, Texas, United States.
Rodriguez-Padron M; Department of Urology, University of Texas Rio Grande Valley (UTRGV), Edinburg, Texas, United States.
Lin CL; Department of Molecular Medicine, University of Texas Health San Antonio (UTHSA), San Antonio, Texas, United States.
Alonzo DG; Department of Urology, University of Texas Rio Grande Valley (UTRGV), Edinburg, Texas, United States.
Huang TH; Department of Molecular Medicine, University of Texas Health San Antonio (UTHSA), San Antonio, Texas, United States.
Svatek RS; Department of Urology, University of Texas Health San Antonio (UTHSA), San Antonio, Texas, United States.
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Źródło:
Cancer medicine [Cancer Med] 2023 Apr; Vol. 12 (7), pp. 8970-8980. Date of Electronic Publication: 2022 Dec 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Killer Cells, Natural*/metabolism
Urinary Bladder Neoplasms*/genetics
Urinary Bladder Neoplasms*/metabolism
Humans ; Biomarkers/metabolism ; Phenotype
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Thermal-exchange HLA-E multimers reveal specificity in HLA-E and NKG2A/CD94 complex interactions.
Autorzy:
Ruibal P; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Derksen I; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
van Wolfswinkel M; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Voogd L; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Franken KLMC; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
El Hebieshy AF; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
van Hall T; Department of Medical Oncology, Oncode Institute, Leiden University Medical Center, Leiden, The Netherlands.
Schoufour TAW; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
Wijdeven RH; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
Ottenhoff THM; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Scheeren FA; Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands.
Joosten SA; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
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Źródło:
Immunology [Immunology] 2023 Mar; Vol. 168 (3), pp. 526-537. Date of Electronic Publication: 2022 Oct 20.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Killer Cells, Natural*
Histocompatibility Antigens Class I*/metabolism
Protein Binding ; Peptides ; Receptors, Antigen, T-Cell ; NK Cell Lectin-Like Receptor Subfamily D/chemistry ; NK Cell Lectin-Like Receptor Subfamily D/metabolism ; NK Cell Lectin-Like Receptor Subfamily C ; HLA-E Antigens
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Characterization of natural killer cells in the blood and airways of cynomolgus macaques during Mycobacterium tuberculosis infection.
Autorzy:
Diedrich CR; Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Rutledge T; Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Baranowski TM; Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Maiello P; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Lin PL; Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
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Źródło:
Journal of medical primatology [J Med Primatol] 2023 Feb; Vol. 52 (1), pp. 24-33. Date of Electronic Publication: 2022 Sep 03.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Killer Cells, Natural*/immunology
Mycobacterium tuberculosis*/immunology
Tuberculosis, Pulmonary*/blood
Tuberculosis, Pulmonary*/immunology
Latent Tuberculosis*/blood
Latent Tuberculosis*/immunology
Lung*/immunology
Animals ; Cytokines/metabolism ; Interferon-gamma/metabolism ; Macaca ; Disease Models, Animal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Brain endothelial CXCL12 attracts protective natural killer cells during ischemic stroke.
Autorzy:
Wang S; Aix-Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), Marseille, France.
de Fabritus L; Aix-Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), Marseille, France.
Kumar PA; Institute of Pharmacology and Toxicology, Jena University Hospital, Jena, Germany.
Werner Y; Institute of Pharmacology and Toxicology, Jena University Hospital, Jena, Germany.
Ma M; Center for Immune-Related Diseases at Shanghai Institute of Immunology, Department of Respiratory and Critical Care Medicine of Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Institute of Cardiovascular Diseases, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Li D; Center for Immune-Related Diseases at Shanghai Institute of Immunology, Department of Respiratory and Critical Care Medicine of Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Siret C; Aix-Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), Marseille, France.
Simic M; Aix-Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), Marseille, France.
Li B; Center for Immune-Related Diseases at Shanghai Institute of Immunology, Department of Respiratory and Critical Care Medicine of Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Kerdiles YM; Aix-Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), Marseille, France.
Hou L; Institute of Cardiovascular Diseases, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Stumm R; Institute of Pharmacology and Toxicology, Jena University Hospital, Jena, Germany.
van de Pavert SA; Aix-Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), Marseille, France. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2023 Jan 11; Vol. 20 (1), pp. 8. Date of Electronic Publication: 2023 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Chemokine CXCL12*/metabolism
Ischemic Stroke*/metabolism
Ischemic Stroke*/pathology
Killer Cells, Natural*/metabolism
Animals ; Mice ; Brain/metabolism ; Brain/pathology ; Endothelial Cells ; Immunity, Innate ; Lymphocytes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
P2X7 receptor activation impairs antitumour activity of natural killer cells.
Autorzy:
Baroja-Mazo A; Biomedical Research Institute of Murcia (IMIB-Pascual Parrilla), University Clinical Hospital Virgen de la Arrixaca, Murcia, Spain.
Peñín-Franch A; Biomedical Research Institute of Murcia (IMIB-Pascual Parrilla), University Clinical Hospital Virgen de la Arrixaca, Murcia, Spain.
Lucas-Ruiz F; Biomedical Research Institute of Murcia (IMIB-Pascual Parrilla), University Clinical Hospital Virgen de la Arrixaca, Murcia, Spain.
de Torre-Minguela C; Biomedical Research Institute of Murcia (IMIB-Pascual Parrilla), University Clinical Hospital Virgen de la Arrixaca, Murcia, Spain.
Alarcón-Vila C; Biomedical Research Institute of Murcia (IMIB-Pascual Parrilla), University Clinical Hospital Virgen de la Arrixaca, Murcia, Spain.
Hernández-Caselles T; Biomedical Research Institute of Murcia (IMIB-Pascual Parrilla), University Clinical Hospital Virgen de la Arrixaca, Murcia, Spain.; Department of Biochemistry and Molecular Biology B and Immunology, Faculty of Medicine, University of Murcia, Murcia, Spain.
Pelegrín P; Biomedical Research Institute of Murcia (IMIB-Pascual Parrilla), University Clinical Hospital Virgen de la Arrixaca, Murcia, Spain.; Department of Biochemistry and Molecular Biology B and Immunology, Faculty of Medicine, University of Murcia, Murcia, Spain.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2023 Jan; Vol. 180 (1), pp. 111-128. Date of Electronic Publication: 2022 Oct 03.
Typ publikacji:
Journal Article
MeSH Terms:
Killer Cells, Natural*/metabolism
Neoplasms*/metabolism
Receptors, Purinergic P2X7*/metabolism
Animals ; Humans ; Mice ; Adenosine Triphosphate/pharmacology ; Interleukin-2/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Can exercise increase natural killer cell infiltration of the prostate?
Autorzy:
Galvão DA; Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia.; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
Taaffe DR; Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia.; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
Kim JS; Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia.; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
Newton RU; Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia.; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
Lucia A; Universidad Europea de Madrid, Madrid, Spain.; Physical Activity and Health Research Group ('PaHerg'), Research Institute of the Hospital 12 de Octubre ('imas12'), Madrid, Spain.
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Źródło:
BJU international [BJU Int] 2023 Jan; Vol. 131 (1), pp. 1-3.
Typ publikacji:
Editorial; Comment
MeSH Terms:
Prostate*
Killer Cells, Natural*
Male ; Humans ; Exercise
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
N6-Methyladenosine (m6A) Modification in Natural Immune Cell-Mediated Inflammatory Diseases.
Autorzy:
Teng Y; Institute of Neurology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.; School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Yi J; Center for Informational Biology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.
Chen J; School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Yang L; Institute of Neurology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.; School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
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Źródło:
Journal of innate immunity [J Innate Immun] 2023; Vol. 15 (1), pp. 804-821. Date of Electronic Publication: 2023 Oct 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Leukocytes*
Killer Cells, Natural*
Cell Differentiation ; Neutrophils
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Natural Killer Cell Receptors and Endometriosis: A Systematic Review.
Autorzy:
Reis JL; Department of Obstetrics and Gynecology, LUZ SAÚDE, Hospital da Luz, 1500-650 Lisboa, Portugal.
Rosa NN; UCD School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.
Ângelo-Dias M; Comprehensive Health Research Centre (CHRC), NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal.; Immunology Department, NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal.
Martins C; Comprehensive Health Research Centre (CHRC), NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal.; Immunology Department, NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal.
Borrego LM; Comprehensive Health Research Centre (CHRC), NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal.; Immunology Department, NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal.; Department of Imunoallergy, LUZ SAÚDE, Hospital da Luz, 1500-650 Lisboa, Portugal.
Lima J; Department of Obstetrics and Gynecology, LUZ SAÚDE, Hospital da Luz, 1500-650 Lisboa, Portugal.; Comprehensive Health Research Centre (CHRC), NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal.; Immunology Department, NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 25; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 25.
Typ publikacji:
Systematic Review; Journal Article; Review
MeSH Terms:
Killer Cells, Natural*
Endometriosis*/pathology
Humans ; Female ; Receptors, Natural Killer Cell ; Endometrium/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Phenotypic and functional characteristics of highly differentiated CD57+NKG2C+ NK cells in HIV-1-infected individuals.
Autorzy:
Kristensen AB; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Wragg KM; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Vanderven HA; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.; Biomedicine, College of Public Health, Medical and Veterinary Sciences, James Cook University, Douglas, Queensland, Australia.
Lee WS; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Silvers J; Melbourne Sexual Health Centre and Department of Infectious Diseases, Alfred Hospital and Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Kent HE; Melbourne Sexual Health Centre and Department of Infectious Diseases, Alfred Hospital and Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Grant MD; Immunology and Infectious Diseases Program, Division of BioMedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.
Kelleher AD; Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia.
Juno JA; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Kent SJ; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.; Melbourne Sexual Health Centre and Department of Infectious Diseases, Alfred Hospital and Central Clinical School, Monash University, Melbourne, Victoria, Australia.; ARC Centre for Excellence in Convergent Bio-Nano Science and Technology, University of Melbourne, Parkville, Victoria, Australia.
Parsons MS; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.; Division of Microbiology and Immunology, Emory National Primate Research Center, Emory University, Atlanta, Georgia, USA.; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
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Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 2022 Dec 15; Vol. 210 (2), pp. 163-174.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Killer Cells, Natural*
HIV Infections*/immunology
Humans ; HIV-1 ; NK Cell Lectin-Like Receptor Subfamily C ; Phenotype
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Functionality of natural killer cells in obese asthma phenotypes.
Autorzy:
Pur Ozyigit L; Adult Allergy Service, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK.; Department of Immunology, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey.
Aktas EC; Department of Immunology, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey.
Gelmez YM; Department of Immunology, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey.
Ozturk AB; Department of Allergy and Immunology, Faculty of Medicine, Koc University, Istanbul.
Gemicioglu B; Department of Pulmonary Diseases, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Deniz G; Department of Immunology, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey.
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Źródło:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2022 Dec; Vol. 52 (12), pp. 1432-1439. Date of Electronic Publication: 2022 Apr 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interleukin-17*/metabolism
Killer Cells, Natural*/metabolism
Humans ; Interferon-gamma ; Interleukin-12/metabolism ; Interleukin-12/pharmacology ; Obesity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Preventing Surgery-Induced NK Cell Dysfunction Using Anti-TGF-β Immunotherapeutics.
Autorzy:
Market M; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H8L6, Canada.; Cancer Therapeutics Program, The Ottawa Hospital Research Institute, Ottawa, ON K1H8L6, Canada.
Tennakoon G; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H8L6, Canada.; Cancer Therapeutics Program, The Ottawa Hospital Research Institute, Ottawa, ON K1H8L6, Canada.
Scaffidi M; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H8L6, Canada.; Cancer Therapeutics Program, The Ottawa Hospital Research Institute, Ottawa, ON K1H8L6, Canada.
Cook DP; Cancer Therapeutics Program, The Ottawa Hospital Research Institute, Ottawa, ON K1H8L6, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H8L6, Canada.
Angka L; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H8L6, Canada.; Cancer Therapeutics Program, The Ottawa Hospital Research Institute, Ottawa, ON K1H8L6, Canada.
Ng J; Cancer Therapeutics Program, The Ottawa Hospital Research Institute, Ottawa, ON K1H8L6, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H8L6, Canada.
Tanese de Souza C; Cancer Therapeutics Program, The Ottawa Hospital Research Institute, Ottawa, ON K1H8L6, Canada.
Kennedy MA; Cancer Therapeutics Program, The Ottawa Hospital Research Institute, Ottawa, ON K1H8L6, Canada.
Vanderhyden BC; Cancer Therapeutics Program, The Ottawa Hospital Research Institute, Ottawa, ON K1H8L6, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H8L6, Canada.
Auer RC; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H8L6, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H8L6, Canada.; Department of Surgery, University of Ottawa, The Ottawa Hospital, Ottawa, ON K1H8L6, Canada.; CI3 Centre for Infection, Immunity, and Inflammation, University of Ottawa, Ottawa, ON K1H8L6, Canada.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 23; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 23.
Typ publikacji:
Journal Article
MeSH Terms:
Killer Cells, Natural*
Neoplasms*/surgery
Transforming Growth Factor beta*/antagonists & inhibitors
Humans ; Leukocytes, Mononuclear/metabolism ; Receptors, Natural Killer Cell/metabolism ; Antibodies, Monoclonal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inhibition of Glucose Uptake Blocks Proliferation but Not Cytotoxic Activity of NK Cells.
Autorzy:
Picard LK; Department for Immunology, Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund (IfADo), D-44139 Dortmund, Germany.
Littwitz-Salomon E; Institute for Virology, University Hospital Essen, D-45147 Essen, Germany.
Waldmann H; Max Planck Institute of Molecular Physiology, D-44227 Dortmund, Germany.; Chemical Biology, Faculty of Chemistry, Technical University Dortmund, D-44227 Dortmund, Germany.
Watzl C; Department for Immunology, Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund (IfADo), D-44139 Dortmund, Germany.
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Źródło:
Cells [Cells] 2022 Nov 03; Vol. 11 (21). Date of Electronic Publication: 2022 Nov 03.
Typ publikacji:
Journal Article
MeSH Terms:
Killer Cells, Natural*
Glycolysis*
Humans ; Cell Proliferation ; Glucose/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
GNLY gene polymorphism: A potential role in understanding psoriasis pathogenesis.
Autorzy:
Khalid HN; Dermatology, Andrology & STDs department, Faculty of Medicine, Menoufia University, Shebin El-Kom, Egypt.
Elghobashy YAE; Biochemistry and Molecular Biology department, Faculty of Medicine, Menoufia University, Shebin El-Kom, Egypt.
Elsayed AN; Resident of Dermatology, Andrology & STDs, at Ministry of Health, Al-Mahala El-Kobra, Egypt.
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Źródło:
Journal of cosmetic dermatology [J Cosmet Dermatol] 2022 Oct; Vol. 21 (10), pp. 4805-4809. Date of Electronic Publication: 2022 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Killer Cells, Natural*/metabolism
Killer Cells, Natural*/pathology
Psoriasis*/metabolism
Humans ; T-Lymphocytes, Cytotoxic ; Polymorphism, Genetic ; Alleles ; Case-Control Studies ; Antigens, Differentiation, T-Lymphocyte/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dual Targeting of Glioblastoma Cells with Bispecific Killer Cell Engagers Directed to EGFR and ErbB2 (HER2) Facilitates Effective Elimination by NKG2D-CAR-Engineered NK Cells.
Autorzy:
Kiefer A; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, 60596 Frankfurt, Germany.; Frankfurt Cancer Institute, Goethe University, 60590 Frankfurt, Germany.
Prüfer M; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, 60596 Frankfurt, Germany.
Röder J; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, 60596 Frankfurt, Germany.; Frankfurt Cancer Institute, Goethe University, 60590 Frankfurt, Germany.
Pfeifer Serrahima J; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, 60596 Frankfurt, Germany.; Frankfurt Cancer Institute, Goethe University, 60590 Frankfurt, Germany.
Bodden M; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, 60596 Frankfurt, Germany.
Kühnel I; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, 60596 Frankfurt, Germany.
Oberoi P; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, 60596 Frankfurt, Germany.
Wels WS; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, 60596 Frankfurt, Germany.; Frankfurt Cancer Institute, Goethe University, 60590 Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, a Partnership between DKFZ and University Hospital Frankfurt, 60590 Frankfurt, Germany.
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Źródło:
Cells [Cells] 2024 Jan 28; Vol. 13 (3). Date of Electronic Publication: 2024 Jan 28.
Typ publikacji:
Journal Article
MeSH Terms:
Glioblastoma*/metabolism
Antibodies, Bispecific*/pharmacology
Humans ; NK Cell Lectin-Like Receptor Subfamily K/metabolism ; Interleukin-15/metabolism ; Cell Line, Tumor ; Killer Cells, Natural ; ErbB Receptors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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