Immune Therapy Targeting E6/E7 Oncogenes of Human Papillomavirus Type 6 (HPV-6) Reduces or Eliminates the Need for Surgical Intervention in the Treatment of HPV-6 Associated Recurrent Respiratory Papillomatosis.
Protective immunity by an engineered DNA vaccine for Mayaro virus.
Autorzy:
Choi H; Vaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, PA, United States of America. Kudchodkar SB; Vaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, PA, United States of America. Reuschel EL; Vaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, PA, United States of America. Asija K; Vaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, PA, United States of America. Borole P; Vaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, PA, United States of America. Ho M; Vaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, PA, United States of America. Wojtak K; Vaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, PA, United States of America. Reed C; Inovio Pharmaceuticals, Plymouth Meeting, PA, United States of America. Ramos S; Inovio Pharmaceuticals, Plymouth Meeting, PA, United States of America. Bopp NE; Department of Pathology, University of Texas Medical Branch, Galveston, TX, United States of America.; Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, TX, United States of America. Aguilar PV; Department of Pathology, University of Texas Medical Branch, Galveston, TX, United States of America.; Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, TX, United States of America.; Center for Tropical Diseases, University of Texas Medical Branch, Galveston, TX, United States of America. Weaver SC; Department of Pathology, University of Texas Medical Branch, Galveston, TX, United States of America.; Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, TX, United States of America.; Center for Tropical Diseases, University of Texas Medical Branch, Galveston, TX, United States of America.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States of America. Kim JJ; Inovio Pharmaceuticals, Plymouth Meeting, PA, United States of America. Humeau L; Inovio Pharmaceuticals, Plymouth Meeting, PA, United States of America. Tebas P; Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America. Weiner DB; Vaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, PA, United States of America. Muthumani K; Vaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, PA, United States of America.
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Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2019 Feb 07; Vol. 13 (2), pp. e0007042. Date of Electronic Publication: 2019 Feb 07 (Print Publication: 2019).
Safety, bioavailability, and pharmacokinetics of VGX-1027-A novel oral anti-inflammatory drug in healthy human subjects.
Autorzy:
Lee JC; Inovio Pharmaceuticals, Inc., Plymouth Meeting, PA, USA. Menacherry S; University of New Haven, Tagliatela School of Engineering, West Haven, CT, USA. Diehl MC; Inovio Pharmaceuticals, Inc., Plymouth Meeting, PA, USA. Giffear MD; Inovio Pharmaceuticals, Inc., Plymouth Meeting, PA, USA. White CJ; C. Jo White Consulting, Lower Gwynedd, PA, USA. Juba R; Inovio Pharmaceuticals, Inc., Plymouth Meeting, PA, USA. Bagarazzi ML; Inovio Pharmaceuticals, Inc., Plymouth Meeting, PA, USA. Muthumani K; University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA. Boyer J; University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA. Agarwal V; NorthEast Bioanalytical Laboratories LLC, Hamden, CT, USA. Nicoletti F; Department of Biomedical and Biotechnological Sciences, the University of Catania, Catania, Italy. Bart S; Optimal Research LLC, Rockville, MD, USA. Kim JJ; Inovio Pharmaceuticals, Inc., Plymouth Meeting, PA, USA. Weiner DB; University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA. Sardesai NY; Inovio Pharmaceuticals, Inc., Plymouth Meeting, PA, USA.
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