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Tytuł:
A Multicenter, Prospective, Observational Study to Evaluate Ethanol-Induced Symptoms in Patients Receiving Docetaxel Chemotherapy.
Autorzy:
Won YW; Division of Hematology and Oncology, Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.
Kang JH; Division of Oncology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Kwon JH; Division of Hematology and Oncology, Department of Internal Medicine, Chungnam National University Sejong Hospital, Chungnam National University College of Medicine, Sejong, Korea.
Koo DH; Division of Hematology/Oncology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
Kang JH; Division of Hematology and Oncology, Department of Internal Medicine, Gyeongsang National University College of Medicine, Jinju, Korea.
Maeng CH; Division of Oncology and Hematology, Department of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University College of Medicine, Seoul, Korea.
Ahn HK; Division of Medical Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea.
Oh SY; Division of Hematology and Oncology, Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea.
Lee DW; Division of Hematology and Oncology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Sohn J; Division of Medical Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.
Oh SY; Division of Hematology and Oncology, Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan University College of Medicine, Yangsan, Korea.
Lee KH; Division of Hematology and Oncology, Department of Internal Medicine, Yeungnam University Hospital, Yeungnam University College of Medicine, Daegu, Korea.
Koh SJ; Division of Hematology and Oncology, Department of Internal Medicine, Ulsan University Hospital, Ulsan University College of Medicine, Ulsan, Korea.
Lee KS; Center for Breast Cancer, Research Institute, National Cancer Center, Goyang, Korea.
Kim CK; Division of Hematology and Oncology, Department of Internal Medicine, Soonchunhyang University Hospital Bucheon, Soonchunhyang University College of Medicine, Bucheon, Korea.
Kim JY; Division of Hematology and Oncology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Ji JH; Division of Hematology and Oncology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.
Kim SB; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Ha JY; Division of Hematology and Oncology, Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.
Kim HY; Division of Hematology and Oncology, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea.
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Źródło:
Cancer research and treatment [Cancer Res Treat] 2023 Oct; Vol. 55 (4), pp. 1096-1103. Date of Electronic Publication: 2023 Apr 07.
Typ publikacji:
Observational Study; Multicenter Study; Journal Article
MeSH Terms:
Antineoplastic Agents*/adverse effects
Breast Neoplasms*/drug therapy
Humans ; Female ; Docetaxel/adverse effects ; Ethanol/adverse effects ; Prospective Studies ; Patients ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Comparison of the outcomes between sorafenib and lenvatinib as the first-line systemic treatment for HBV-associated hepatocellular carcinoma: a propensity score matching analysis.
Autorzy:
Choi NR; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
Kim JY; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
Hong JH; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
Hur MH; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
Cho H; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
Park MK; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
Kim J; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
Lee YB; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
Cho EJ; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
Lee JH; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
Yu SJ; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
Yoon JH; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
Kim YJ; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea. .; Department of Internal Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Korea. .
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Źródło:
BMC gastroenterology [BMC Gastroenterol] 2022 Mar 25; Vol. 22 (1), pp. 135. Date of Electronic Publication: 2022 Mar 25.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Antineoplastic Agents*/therapeutic use
Carcinoma, Hepatocellular*
Liver Neoplasms*
Hepatitis B virus ; Humans ; Phenylurea Compounds ; Propensity Score ; Quinolines ; Retrospective Studies ; Sorafenib/therapeutic use ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Biomarker LEPRE1 induces pelitinib-specific drug responsiveness by regulating ABCG2 expression and tumor transition states in human leukemia and lung cancer.
Autorzy:
Lee AR; Department of Advanced Toxicology, Korea Institute of Toxicology (KIT), Daejeon, 34114, Republic of Korea.; Bio Center, LegoChem Biosciences, Inc., Daejeon, 34002, Republic of Korea.
Lee S; Genome Data Integration Centre, Syntekabio Inc., Daejeon, 34025, Republic of Korea.; Department of Computer Science and Engineering, Seoul National University, Seoul, 08826, Republic of Korea.
Shin JY; Genome Data Integration Centre, Syntekabio Inc., Daejeon, 34025, Republic of Korea.
Kim JY; Department of Advanced Toxicology, Korea Institute of Toxicology (KIT), Daejeon, 34114, Republic of Korea.
Moon KS; Department of Advanced Toxicology, Korea Institute of Toxicology (KIT), Daejeon, 34114, Republic of Korea. .
Jung J; Genome Data Integration Centre, Syntekabio Inc., Daejeon, 34025, Republic of Korea. .
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Źródło:
Scientific reports [Sci Rep] 2022 Feb 21; Vol. 12 (1), pp. 2928. Date of Electronic Publication: 2022 Feb 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers, Tumor*
ATP Binding Cassette Transporter, Subfamily G, Member 2/*genetics
ATP Binding Cassette Transporter, Subfamily G, Member 2/*metabolism
Aminoquinolines/*pharmacology
Aniline Compounds/*pharmacology
Antineoplastic Agents/*pharmacology
Epithelial-Mesenchymal Transition/*genetics
Gene Expression Regulation, Leukemic/*genetics
Gene Expression Regulation, Neoplastic/*genetics
Leukemia, Myeloid, Acute/*genetics
Leukemia, Myeloid, Acute/*pathology
Lung Neoplasms/*genetics
Lung Neoplasms/*pathology
Membrane Glycoproteins/*genetics
Membrane Glycoproteins/*physiology
Neoplasm Proteins/*genetics
Neoplasm Proteins/*metabolism
Prolyl Hydroxylases/*genetics
Prolyl Hydroxylases/*physiology
Proteoglycans/*genetics
Proteoglycans/*physiology
Cell Line, Tumor ; Drug Resistance, Neoplasm/genetics ; Humans ; Leukemia, Myeloid, Acute/diagnosis ; Lung Neoplasms/diagnosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clinical Characteristics and Treatment Outcomes of Childhood Acute Promyelocytic Leukemia in Korea: A Nationwide Multicenter Retrospective Study by Korean Pediatric Oncology Study Group.
Autorzy:
Park KM; Department of Pediatrics, Dongnam Institute of Radiological and Medical Sciences, Busan, Korea.
Yoo KH; Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Kim SK; Department of Pediatrics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Lee JW; Department of Pediatrics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Chung NG; Department of Pediatrics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Ju HY; Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Koo HH; Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Lyu CJ; Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Han SM; Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Han JW; Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Choi JY; Department of Pediatrics, Seoul National University Cancer Institute, Seoul National University College of Medicine, Seoul, Korea.
Hong KT; Department of Pediatrics, Seoul National University Cancer Institute, Seoul National University College of Medicine, Seoul, Korea.
Kang HJ; Department of Pediatrics, Seoul National University Cancer Institute, Seoul National University College of Medicine, Seoul, Korea.
Shin HY; Department of Pediatrics, Seoul National University Cancer Institute, Seoul National University College of Medicine, Seoul, Korea.
Im HJ; Division of Pediatric Hematology and Oncology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea.
Koh KN; Division of Pediatric Hematology and Oncology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea.
Kim H; Division of Pediatric Hematology and Oncology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea.
Kook H; Department of Pediatrics, Chonnam National University Hwasun Hospital, Chonnam National University medical school, Gwangju, Korea.
Baek HJ; Department of Pediatrics, Chonnam National University Hwasun Hospital, Chonnam National University medical school, Gwangju, Korea.
Kim BR; Department of Pediatrics, Chonnam National University Hwasun Hospital, Chonnam National University medical school, Gwangju, Korea.
Yang EJ; Department of Pediatrics, Pusan National University School of Medicines, Yangsan, Korea.
Lim JY; Department of Pediatrics, Gyeongsang National University College of Medicine, Jinju, Korea.
Park ES; Department of Pediatrics, Gyeongsang National University College of Medicine, Jinju, Korea.
Choi EJ; Department of Pediatrics, Daegu Catholic University School of Medicine, Daegu, Korea.
Park SK; Department of Pediatrics, University of Ulsan School of Medicine, Ulsan, Korea.
Lee JM; Department of Pediatrics, Yeungnam University College of Medicine, Daegu, Korea.
Shim YJ; Department of Pediatrics, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Korea.
Kim JY; Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Korea.
Park JK; Department of Pediatrics, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Kong SG; Department of Pediatrics, Kosin University of Medicine, Busan, Korea.
Choi YB; Departments of Pediatrics, Ajou University School of Medicine, Suwon, Korea.
Cho B; Department of Pediatrics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Lim YT; Department of Pediatrics, Pusan National University School of Medicines, Yangsan, Korea.
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Źródło:
Cancer research and treatment [Cancer Res Treat] 2022 Jan; Vol. 54 (1), pp. 269-276. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji:
Journal Article; Multicenter Study
MeSH Terms:
Antineoplastic Agents/*administration & dosage
Leukemia, Promyelocytic, Acute/*drug therapy
Leukemia, Promyelocytic, Acute/*mortality
Tretinoin/*administration & dosage
Adolescent ; Antineoplastic Agents/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Child ; Child, Preschool ; Disease-Free Survival ; Female ; Humans ; Induction Chemotherapy/methods ; Infant ; Leukocyte Count ; Male ; Progression-Free Survival ; Remission Induction ; Republic of Korea/epidemiology ; Retrospective Studies ; Treatment Outcome ; Tretinoin/adverse effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Survival impact of additional chemotherapy after adjuvant concurrent chemoradiation in patients with early cervical cancer who underwent radical hysterectomy.
Autorzy:
Kim SI; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, 101, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Kim JY; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, 101, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Wee CW; Department of Radiation Oncology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, 20, Boramae-ro 5-gil, Dongjak-gu, Seoul, 07061, Republic of Korea.
Lee M; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, 101, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Kim HS; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, 101, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Chung HH; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, 101, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Lee TS; Department of Obstetrics and Gynecology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, 20, Boramae-ro 5-gil, Dongjak-gu, Seoul, 07061, Republic of Korea.
Jeon HW; Department of Obstetrics and Gynecology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, 20, Boramae-ro 5-gil, Dongjak-gu, Seoul, 07061, Republic of Korea.
Park NH; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, 101, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Song YS; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, 101, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Kim TH; Department of Obstetrics and Gynecology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, 20, Boramae-ro 5-gil, Dongjak-gu, Seoul, 07061, Republic of Korea. .
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Źródło:
BMC cancer [BMC Cancer] 2021 Nov 22; Vol. 21 (1), pp. 1260. Date of Electronic Publication: 2021 Nov 22.
Typ publikacji:
Journal Article; Multicenter Study
MeSH Terms:
Chemoradiotherapy, Adjuvant*
Antineoplastic Agents/*therapeutic use
Hysterectomy/*methods
Uterine Cervical Neoplasms/*mortality
Uterine Cervical Neoplasms/*therapy
Adult ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Case-Control Studies ; Disease-Free Survival ; Female ; Humans ; Lymph Node Excision ; Lymphatic Metastasis ; Middle Aged ; Pelvis ; Risk Factors ; Survival Analysis ; Uterine Cervical Neoplasms/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Determinants of quality of life in women immediately following the completion of primary treatment of breast cancer: A cross-sectional study.
Autorzy:
Park JH; College of Nursing Research Institute of Nursing Science, Ajou University, Suwon, South Korea.
Jung YS; Department of Breast Surgery, School of Medicine, Ajou University, Suwon, South Korea.
Kim JY; Department of Breast Surgery, School of Medicine, Ajou University, Suwon, South Korea.
Bae SH; College of Nursing Research Institute of Nursing Science, Ajou University, Suwon, South Korea.
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Źródło:
PloS one [PLoS One] 2021 Oct 15; Vol. 16 (10), pp. e0258447. Date of Electronic Publication: 2021 Oct 15 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Quality of Life*
Antineoplastic Agents/*therapeutic use
Breast Neoplasms/*drug therapy
Cancer Survivors/*psychology
Adult ; Breast Neoplasms/psychology ; Cross-Sectional Studies ; Female ; Humans ; Middle Aged ; Self Efficacy ; Social Support ; Surveys and Questionnaires
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A novel HSP90 inhibitor targeting the C-terminal domain attenuates trastuzumab resistance in HER2-positive breast cancer.
Autorzy:
Park JM; Division of Medical Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul, 152-703, Republic of Korea.; Brain Korea 21 Program for Biomedical Science, Korea University College of Medicine, Korea University, Seoul, 152-703, Republic of Korea.
Kim YJ; Division of Medical Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul, 152-703, Republic of Korea.; Brain Korea 21 Program for Biomedical Science, Korea University College of Medicine, Korea University, Seoul, 152-703, Republic of Korea.; Department of Biomedical Research Center, Korea University Guro Hospital, Korea University, Guro Hospital Campus, 97 Gurodong-gil, Guro-gu, Seoul, 08308, Republic of Korea.
Park S; Division of Medical Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul, 152-703, Republic of Korea.; Brain Korea 21 Program for Biomedical Science, Korea University College of Medicine, Korea University, Seoul, 152-703, Republic of Korea.
Park M; Division of Medical Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul, 152-703, Republic of Korea.; Brain Korea 21 Program for Biomedical Science, Korea University College of Medicine, Korea University, Seoul, 152-703, Republic of Korea.
Farrand L; Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, 5000, Australia.
Nguyen CT; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul, 08826, Republic of Korea.
Ann J; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul, 08826, Republic of Korea.
Nam G; School of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi-do, 16419, Republic of Korea.
Park HJ; School of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi-do, 16419, Republic of Korea.
Lee J; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul, 08826, Republic of Korea. .
Kim JY; Division of Medical Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul, 152-703, Republic of Korea. .; Department of Biomedical Research Center, Korea University Guro Hospital, Korea University, Guro Hospital Campus, 97 Gurodong-gil, Guro-gu, Seoul, 08308, Republic of Korea. .
Seo JH; Division of Medical Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul, 152-703, Republic of Korea. .; Brain Korea 21 Program for Biomedical Science, Korea University College of Medicine, Korea University, Seoul, 152-703, Republic of Korea. .; Department of Biomedical Research Center, Korea University Guro Hospital, Korea University, Guro Hospital Campus, 97 Gurodong-gil, Guro-gu, Seoul, 08308, Republic of Korea. .
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Źródło:
Molecular cancer [Mol Cancer] 2020 Nov 20; Vol. 19 (1), pp. 161. Date of Electronic Publication: 2020 Nov 20.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Antineoplastic Agents/*pharmacology
Biomarkers, Tumor/*metabolism
Breast Neoplasms/*drug therapy
Drug Resistance, Neoplasm/*drug effects
HSP90 Heat-Shock Proteins/*antagonists & inhibitors
Trastuzumab/*pharmacology
Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents, Immunological/pharmacology ; Apoptosis ; Biomarkers, Tumor/genetics ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cell Proliferation ; Female ; Humans ; Mice ; Neoplastic Stem Cells ; Protein Domains ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Phase I and pharmacokinetic study of the vascular-disrupting agent CKD-516 (NOV120401) in patients with refractory solid tumors.
Autorzy:
Kim HK; National Cancer Center Hospital, Goyang-si, Gyeonggi-do, Republic of Korea.
Kang JW; National Cancer Center Hospital, Goyang-si, Gyeonggi-do, Republic of Korea.
Park YW; National Oncoventure, National Cancer Center, Goyang-si, Gyeonggi-do, Republic of Korea.
Kim JY; National Oncoventure, National Cancer Center, Goyang-si, Gyeonggi-do, Republic of Korea.
Kim M; National Oncoventure, National Cancer Center, Goyang-si, Gyeonggi-do, Republic of Korea.
Kim SJ; CKD Research Center, Yongin-si, Gyeonggi-do, Republic of Korea.
Kim SM; CKD Research Center, Yongin-si, Gyeonggi-do, Republic of Korea.
Ho Ryu K; CKD Research Center, Yongin-si, Gyeonggi-do, Republic of Korea.
Yoon S; Clinical Trials Center, Seoul National University Bundang Hospital, Bundang-gu, Seongnam-si, Republic of Korea.
Kim Y; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine, Seoul, Republic of Korea.
Cho JY; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine, Seoul, Republic of Korea.
Lee KS; National Cancer Center Hospital, Goyang-si, Gyeonggi-do, Republic of Korea.
Yun T; National Cancer Center Hospital, Goyang-si, Gyeonggi-do, Republic of Korea.
Kim K; National Cancer Center Hospital, Goyang-si, Gyeonggi-do, Republic of Korea.
Kwak MH; National Cancer Center Hospital, Goyang-si, Gyeonggi-do, Republic of Korea.
Kim TS; National Cancer Center Hospital, Goyang-si, Gyeonggi-do, Republic of Korea.
Chung J; National Cancer Center Hospital, Goyang-si, Gyeonggi-do, Republic of Korea.
Park JW; National Cancer Center Hospital, Goyang-si, Gyeonggi-do, Republic of Korea.
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Źródło:
Pharmacology research & perspectives [Pharmacol Res Perspect] 2020 Apr; Vol. 8 (2), pp. e00568.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*pharmacokinetics
Benzophenones/*pharmacokinetics
Neoplasms/*metabolism
Valine/*analogs & derivatives
Administration, Oral ; Adult ; Aged ; Antineoplastic Agents/adverse effects ; Antineoplastic Agents/blood ; Benzophenones/adverse effects ; Benzophenones/blood ; Female ; Humans ; Male ; Middle Aged ; Neoplasms/blood ; Neoplasms/drug therapy ; Treatment Outcome ; Valine/adverse effects ; Valine/blood ; Valine/pharmacokinetics ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Establishment of chemosensitivity tests in triple-negative and BRCA-mutated breast cancer patient-derived xenograft models.
Autorzy:
Park HS; Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
Lee JD; Department of Human Biology and Genomics, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Korea.
Kim JY; Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
Park S; Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
Kim JH; Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
Han HJ; Avison Biomedical Research Center, Yonsei University College of Medicine, Seoul, Korea.
Choi YA; Avison Biomedical Research Center, Yonsei University College of Medicine, Seoul, Korea.
Choi AR; Avison Biomedical Research Center, Yonsei University College of Medicine, Seoul, Korea.
Sohn JH; Division of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Kim SI; Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
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Źródło:
PloS one [PLoS One] 2019 Dec 10; Vol. 14 (12), pp. e0225082. Date of Electronic Publication: 2019 Dec 10 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Xenograft Model Antitumor Assays*
Antineoplastic Agents/*therapeutic use
BRCA1 Protein/*genetics
Carboplatin/*therapeutic use
Phthalazines/*therapeutic use
Piperazines/*therapeutic use
Triple Negative Breast Neoplasms/*drug therapy
Animals ; Disease Models, Animal ; Female ; Humans ; Mice ; Mice, Inbred NOD ; Neoadjuvant Therapy ; Treatment Outcome ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MiR-1208 Increases the Sensitivity to Cisplatin by Targeting TBCK in Renal Cancer Cells.
Autorzy:
Kim EA; Department of Anatomy, College of Medicine, Yeungnam University, 170 Hyeonchung-Ro, Nam-Gu, Daegu 42415, Korea.
Jang JH; Department of Anatomy, College of Medicine, Yeungnam University, 170 Hyeonchung-Ro, Nam-Gu, Daegu 42415, Korea.
Sung EG; Department of Anatomy, College of Medicine, Yeungnam University, 170 Hyeonchung-Ro, Nam-Gu, Daegu 42415, Korea.
Song IH; Department of Anatomy, College of Medicine, Yeungnam University, 170 Hyeonchung-Ro, Nam-Gu, Daegu 42415, Korea.
Kim JY; Department of Anatomy, College of Medicine, Yeungnam University, 170 Hyeonchung-Ro, Nam-Gu, Daegu 42415, Korea.
Lee TJ; Department of Anatomy, College of Medicine, Yeungnam University, 170 Hyeonchung-Ro, Nam-Gu, Daegu 42415, Korea. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 Jul 19; Vol. 20 (14). Date of Electronic Publication: 2019 Jul 19.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
Carcinoma, Renal Cell/*genetics
Cisplatin/*pharmacology
Drug Resistance, Neoplasm/*genetics
Kidney Neoplasms/*genetics
MicroRNAs/*genetics
Protein Serine-Threonine Kinases/*genetics
3' Untranslated Regions ; Apoptosis/drug effects ; Apoptosis/genetics ; Binding Sites ; Caspases/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Gene Expression Regulation, Neoplastic ; Humans ; RNA Interference ; TNF-Related Apoptosis-Inducing Ligand/genetics ; TNF-Related Apoptosis-Inducing Ligand/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
RNAi Screening-based Identification of USP10 as a Novel Regulator of Paraptosis.
Autorzy:
Kim JY; Department of Biomedical Sciences, Department of Biochemistry and Molecular biology, Ajou University Graduate School of Medicine, 16499, Suwon, Korea.; Institut Pasteur Korea, Seongnam, Korea.
Lee DM; Department of Biomedical Sciences, Department of Biochemistry and Molecular biology, Ajou University Graduate School of Medicine, 16499, Suwon, Korea.
Woo HG; Department of Physiology, Department of Biomedical Sciences, Ajou University School of Medicine, Suwon, Korea.
Kim KD; Institut Pasteur Korea, Seongnam, Korea.
Lee HJ; Department of Biomedical Sciences, Department of Biochemistry and Molecular biology, Ajou University Graduate School of Medicine, 16499, Suwon, Korea.
Kwon YJ; Institut Pasteur Korea, Seongnam, Korea. .; Early Discovery, Ksilink, 16, rue d'Ankara, 67000, Strasbourg, France. .
Choi KS; Department of Biomedical Sciences, Department of Biochemistry and Molecular biology, Ajou University Graduate School of Medicine, 16499, Suwon, Korea. .
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Źródło:
Scientific reports [Sci Rep] 2019 Mar 20; Vol. 9 (1), pp. 4909. Date of Electronic Publication: 2019 Mar 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*pharmacology
Cell Death/*genetics
Curcumin/*pharmacology
Endoplasmic Reticulum/*drug effects
Mitochondria/*drug effects
Ubiquitin Thiolesterase/*genetics
Benzylamines/pharmacology ; Breast Neoplasms/drug therapy ; Breast Neoplasms/enzymology ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Cell Death/drug effects ; Cell Line, Tumor ; Endoplasmic Reticulum/enzymology ; Endoplasmic Reticulum/genetics ; Female ; Gene Library ; High-Throughput Screening Assays ; Humans ; Membrane Potential, Mitochondrial/drug effects ; Mitochondria/enzymology ; Mitochondria/genetics ; Quinazolines/pharmacology ; RNA Interference ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Ubiquitin Thiolesterase/antagonists & inhibitors ; Ubiquitin Thiolesterase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Functional Biological Activity of Sorafenib as a Tumor-Treating Field Sensitizer for Glioblastoma Therapy.
Autorzy:
Jo Y; Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea. .; Department of Bio-Convergence Engineering, Korea University, Seoul 02842, Korea. .
Kim EH; Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea. .
Sai S; Department of Basic Medical Sciences for Radiation Damages, National Institute of Radiological Sciences, Chiba 263-0024, Japan. .
Kim JS; Division of RI-Convergence Research, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea. .
Cho JM; Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea. .
Kim H; Division of RI-Convergence Research, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea. .
Baek JH; Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea. .
Kim JY; Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea. .
Hwang SG; Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea. .
Yoon M; Department of Bio-Convergence Engineering, Korea University, Seoul 02842, Korea. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2018 Nov 21; Vol. 19 (11). Date of Electronic Publication: 2018 Nov 21.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*therapeutic use
Brain Neoplasms/*therapy
Electric Stimulation Therapy/*methods
Glioblastoma/*therapy
Sorafenib/*therapeutic use
Animals ; Antineoplastic Agents/administration & dosage ; Autophagy ; Brain Neoplasms/drug therapy ; Cell Cycle Checkpoints ; Cell Line, Tumor ; Combined Modality Therapy/methods ; Glioblastoma/drug therapy ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Poly(ADP-ribose) Polymerases/metabolism ; Reactive Oxygen Species/metabolism ; Sorafenib/administration & dosage
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
All-Trans Retinoic Acid Enhances Matrix Metalloproteinase 2 Expression and Secretion in Human Myeloid Leukemia THP-1 Cells.
Autorzy:
Vu HT; Department of Life Science, Gachon University, Seongnam, Kyeonggi-Do 461-701, Republic of Korea.
Hoang TX; Department of Life Science, Gachon University, Seongnam, Kyeonggi-Do 461-701, Republic of Korea.
Kim JY; Department of Life Science, Gachon University, Seongnam, Kyeonggi-Do 461-701, Republic of Korea.
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Źródło:
BioMed research international [Biomed Res Int] 2018 Aug 26; Vol. 2018, pp. 5971080. Date of Electronic Publication: 2018 Aug 26 (Print Publication: 2018).
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
Leukemia, Myeloid/*pathology
Matrix Metalloproteinase 2/*metabolism
Tretinoin/*pharmacology
Cell Differentiation ; Humans ; Matrix Metalloproteinase 2/drug effects ; THP-1 Cells ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel herbal medicine LA16001 ameliorates cisplatin-induced anorexia.
Autorzy:
Woo SM; Department of Cancer Preventive Material Development, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Lee KM; Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Lee GR; Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Park JY; Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Lee HJ; Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Bahn HJ; Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Yoon HS; Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Kim JY; Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Shin YC; Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
Cho SG; Department of Biotechnology, Korea National University of Transportation, Jeungpyeong, Chungbuk 368‑701, Republic of Korea.
Ko SG; Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2018 Feb; Vol. 17 (2), pp. 2665-2672. Date of Electronic Publication: 2017 Nov 28.
Typ publikacji:
Journal Article
MeSH Terms:
Anorexia/*etiology
Antineoplastic Agents/*adverse effects
Cisplatin/*adverse effects
Plant Extracts/*pharmacology
Animals ; Anorexia/drug therapy ; Anorexia/metabolism ; Appetite/drug effects ; Disease Models, Animal ; Eating/drug effects ; Herbal Medicine ; Hormones/metabolism ; Humans ; Janus Kinase 1/metabolism ; Male ; Mice ; Neoplasms/complications ; Neoplasms/drug therapy ; STAT3 Transcription Factor/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inhibitory effect of emodin on fatty acid synthase, colon cancer proliferation and apoptosis.
Autorzy:
Lee KH; Department of Surgery, Chungnam National University Hospital, Daejeon 301‑721, Republic of Korea.
Lee MS; Surgical Oncology Research Laboratory, Biomedical Research Institute, Chungnam National University Hospital, Daejeon 301‑721, Republic of Korea.
Cha EY; Surgical Oncology Research Laboratory, Biomedical Research Institute, Chungnam National University Hospital, Daejeon 301‑721, Republic of Korea.
Sul JY; Department of Surgery, Chungnam National University Hospital, Daejeon 301‑721, Republic of Korea.
Lee JS; Department of Surgery, Chungnam National University Hospital, Daejeon 301‑721, Republic of Korea.
Kim JS; Department of Surgery, Chungnam National University Hospital, Daejeon 301‑721, Republic of Korea.
Park JB; Department of Surgery, Chungnam National University Hospital, Daejeon 301‑721, Republic of Korea.
Kim JY; Department of Surgery, Chungnam National University Hospital, Daejeon 301‑721, Republic of Korea.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2017 Apr; Vol. 15 (4), pp. 2163-2173. Date of Electronic Publication: 2017 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Cell Proliferation/*drug effects
Colonic Neoplasms/*drug therapy
Emodin/*pharmacology
Fatty Acid Synthases/*antagonists & inhibitors
Protein Kinase Inhibitors/*pharmacology
Cell Cycle/drug effects ; Cell Survival/drug effects ; Colon/drug effects ; Colon/metabolism ; Colon/pathology ; Colonic Neoplasms/metabolism ; Colonic Neoplasms/pathology ; Fatty Acid Synthases/metabolism ; HCT116 Cells ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The triptolide derivative MRx102 inhibits Wnt pathway activation and has potent anti-tumor effects in lung cancer.
Autorzy:
Reno TA; Division of Thoracic Surgery, City of Hope Medical Center, 1500 E. Duarte Rd., Duarte, CA, 91010, USA. .
Tong SW; Department of Pathology, City of Hope Medical Center, Duarte, CA, USA.
Wu J; Division of Comparative Medicine, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, USA.
Fidler JM; MyeloRx LLC, Vallejo, CA, USA.
Nelson R; Department of Biostatistics, City of Hope Medical Center, Duarte, CA, USA.
Kim JY; Division of Thoracic Surgery, City of Hope Medical Center, 1500 E. Duarte Rd., Duarte, CA, 91010, USA.
Raz DJ; Division of Thoracic Surgery, City of Hope Medical Center, 1500 E. Duarte Rd., Duarte, CA, 91010, USA.
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Źródło:
BMC cancer [BMC Cancer] 2016 Jul 11; Vol. 16, pp. 439. Date of Electronic Publication: 2016 Jul 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Antineoplastic Agents/*therapeutic use
Carcinoma, Non-Small-Cell Lung/*drug therapy
Lung Neoplasms/*drug therapy
Phenanthrenes/*therapeutic use
Wnt Signaling Pathway/*drug effects
A549 Cells ; Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/adverse effects ; Apoptosis/drug effects ; Carboplatin/administration & dosage ; Carboplatin/therapeutic use ; Carcinoma, Non-Small-Cell Lung/metabolism ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Diterpenes/adverse effects ; Diterpenes/therapeutic use ; Drug Evaluation, Preclinical ; Drug Therapy, Combination ; Epoxy Compounds/adverse effects ; Epoxy Compounds/therapeutic use ; Humans ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Mice ; Neoplasm Invasiveness ; Phenanthrenes/administration & dosage ; Phenanthrenes/adverse effects ; Repressor Proteins/metabolism ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Role of Chemotherapy in Stage II Nasopharyngeal Carcinoma Treated with Curative Radiotherapy.
Autorzy:
Kang MK; Department of Radiation Oncology, Yeungnam University College of Medicine, Daegu, Korea.
Oh D; Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Cho KH; Proton Therapy Center, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Moon SH; Proton Therapy Center, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Wu HG; Department of Radiation Oncology, Seoul National University College of Medicine, Seoul, Korea.
Heo DS; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Ahn YC; Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Park K; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Park HJ; Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Park JS; Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Keum KC; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Korea.
Cha J; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Korea.
Kim JW; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Korea.
Kim YS; Department of Radiation Oncology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Kang JH; Department of Medical Oncology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Oh YT; Department of Radiation Oncology, Ajou University School of Medicine, Suwon, Korea.
Kim JY; Department of Radiation Oncology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Kim SH; Department of Radiation Oncology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
Kim JH; Department of Radiation Oncology, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.
Lee CG; Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Korea.
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Źródło:
Cancer research and treatment [Cancer Res Treat] 2015 Oct; Vol. 47 (4), pp. 871-8. Date of Electronic Publication: 2015 Feb 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*therapeutic use
Nasopharyngeal Neoplasms/*drug therapy
Nasopharyngeal Neoplasms/*radiotherapy
Antineoplastic Agents/administration & dosage ; Chemotherapy, Adjuvant ; Female ; Humans ; Male ; Middle Aged ; Nasopharyngeal Neoplasms/classification ; Neoadjuvant Therapy ; Neoplasm Staging ; Prognosis ; Survival Analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Corosolic acid enhances 5-fluorouracil-induced apoptosis against SNU-620 human gastric carcinoma cells by inhibition of mammalian target of rapamycin.
Autorzy:
Lee HS; Department of Surgery, Chungnam National University Hospital, Daejeon 301‑721, Republic of Korea.
Park JB; Department of Surgery, Chungnam National University Hospital, Daejeon 301‑721, Republic of Korea.
Lee MS; Surgical Oncology Research Lab, Chungnam National University Hospital, Daejeon 301‑721, Republic of Korea.
Cha EY; Surgical Oncology Research Lab, Chungnam National University Hospital, Daejeon 301‑721, Republic of Korea.
Kim JY; Department of Surgery, Chungnam National University Hospital, Daejeon 301‑721, Republic of Korea.
Sul JY; Department of Surgery, Chungnam National University Hospital, Daejeon 301‑721, Republic of Korea.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2015 Sep; Vol. 12 (3), pp. 4782-4788. Date of Electronic Publication: 2015 Jun 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Fluorouracil/*pharmacology
TOR Serine-Threonine Kinases/*antagonists & inhibitors
Triterpenes/*pharmacology
Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Drug Synergism ; Humans ; Signal Transduction ; Stomach Neoplasms ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Cancer cell growth inhibitory effect of bee venom via increase of death receptor 3 expression and inactivation of NF-kappa B in NSCLC cells.
Autorzy:
Choi KE; College of Pharmacy and Medical Research Center, Chungbuk National University, 52 Naesudong-ro, Heungdeok-gu, Cheongju, Chungbuk 361-763, Korea. .
Hwang CJ; College of Pharmacy and Medical Research Center, Chungbuk National University, 52 Naesudong-ro, Heungdeok-gu, Cheongju, Chungbuk 361-763, Korea. .
Gu SM; College of Pharmacy and Medical Research Center, Chungbuk National University, 52 Naesudong-ro, Heungdeok-gu, Cheongju, Chungbuk 361-763, Korea. .
Park MH; College of Pharmacy and Medical Research Center, Chungbuk National University, 52 Naesudong-ro, Heungdeok-gu, Cheongju, Chungbuk 361-763, Korea. .
Kim JH; College of Pharmacy and Medical Research Center, Chungbuk National University, 52 Naesudong-ro, Heungdeok-gu, Cheongju, Chungbuk 361-763, Korea. .
Park JH; College of Pharmacy and Medical Research Center, Chungbuk National University, 52 Naesudong-ro, Heungdeok-gu, Cheongju, Chungbuk 361-763, Korea. .
Ahn YJ; College of Pharmacy and Medical Research Center, Chungbuk National University, 52 Naesudong-ro, Heungdeok-gu, Cheongju, Chungbuk 361-763, Korea. .
Kim JY; College of Pharmacy and Medical Research Center, Chungbuk National University, 52 Naesudong-ro, Heungdeok-gu, Cheongju, Chungbuk 361-763, Korea. .
Song MJ; Department of Obstetrics and Gynecology, Daejeon St. Mary's Hospital, College of Medicine, the Catholic University of Korea, 64 Daeheung-ro, Jung-gu, Daejeon 301-723, Korea. .
Song HS; College of Oriental Medicine, Gachon University, San 65, Bokjeong-dong, Sujeong-gu, Seongnam, Gyeonggii 461-701, Korea. .
Han SB; College of Pharmacy and Medical Research Center, Chungbuk National University, 52 Naesudong-ro, Heungdeok-gu, Cheongju, Chungbuk 361-763, Korea. .
Hong JT; College of Pharmacy and Medical Research Center, Chungbuk National University, 52 Naesudong-ro, Heungdeok-gu, Cheongju, Chungbuk 361-763, Korea. .
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Źródło:
Toxins [Toxins (Basel)] 2014 Jul 25; Vol. 6 (8), pp. 2210-28. Date of Electronic Publication: 2014 Jul 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*pharmacology
Bee Venoms/*pharmacology
NF-kappa B/*antagonists & inhibitors
Receptors, Tumor Necrosis Factor, Member 25/*metabolism
Apoptosis/drug effects ; Carcinoma, Non-Small-Cell Lung/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Humans ; Lung Neoplasms/metabolism ; NF-kappa B/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Synergistic anti-cancer effect of phenformin and oxamate.
Autorzy:
Miskimins WK; Cancer Biology Research Center, Sanford Research/USD, Sioux Falls, South Dakota, United States of America ; Department of Obstetrics and Gynecology and Division of Basic Biomedical Sciences, Sanford School of Medicine of the University of South Dakota, Sioux Falls, South Dakota, United States of America.
Ahn HJ; Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Kim JY; Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Ryu S; Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Jung YS; Head and Neck Oncology Clinic, Center of Specific Organs Cancer, Center for Thyroid Cancer, Research Institute and Hospital, National Cancer Center, Goyang-si, Gyeonggi-do, Korea.
Choi JY; Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
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Źródło:
PloS one [PLoS One] 2014 Jan 21; Vol. 9 (1), pp. e85576. Date of Electronic Publication: 2014 Jan 21 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*pharmacology
Colonic Neoplasms/*drug therapy
Oxamic Acid/*pharmacology
Phenformin/*pharmacology
Adenosine Triphosphate/antagonists & inhibitors ; Adenosine Triphosphate/biosynthesis ; Animals ; Apoptosis/drug effects ; Cell Line, Tumor ; Colonic Neoplasms/metabolism ; Colonic Neoplasms/pathology ; Drug Combinations ; Drug Synergism ; Electron Transport Complex I/antagonists & inhibitors ; Electron Transport Complex I/metabolism ; Fluorodeoxyglucose F18/administration & dosage ; Glycolysis/drug effects ; L-Lactate Dehydrogenase/antagonists & inhibitors ; L-Lactate Dehydrogenase/metabolism ; Mice ; Mice, Inbred C57BL ; Mitochondria/drug effects ; Mitochondria/metabolism ; Neoplasm Transplantation ; Reactive Oxygen Species ; Tumor Burden/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 26

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