Autor: "Kim YH" - OpacWWW - Prolib Integro

Skocz do pozycji: 1.

Tytuł:: Inhibition of soluble epoxide hydrolase by phytochemical constituents of the root bark of Ulmus davidiana var. japonica .
Autorzy:: Kim JH; Department of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Jeonju, Korea.
Park JS; College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea.
Lee YJ; Department of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Jeonju, Korea.
Choi S; Department of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Jeonju, Korea.
Kim YH; College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea.
Yang SY; College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea.; Department of Pharmaceutical Engineering, Sangji University, Wonju-si, Republic of Korea.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 1049-1055.
Typ publikacji:: Journal Article
MeSH Terms:: Enzyme Inhibitors/*pharmacology
Epoxide Hydrolases/*antagonists & inhibitors
Phytochemicals/*pharmacology
Plant Extracts/*pharmacology
Ulmus/*chemistry
Dose-Response Relationship, Drug ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/isolation & purification ; Epoxide Hydrolases/metabolism ; Humans ; Molecular Docking Simulation ; Molecular Structure ; Phytochemicals/chemistry ; Phytochemicals/isolation & purification ; Plant Bark/chemistry ; Plant Extracts/chemistry ; Plant Extracts/isolation & purification ; Plant Roots/chemistry ; Solubility ; Structure-Activity Relationship

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Skocz do pozycji: 2.

Tytuł:: Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I.
Autorzy:: Zhang Q; Center for Disease Prevention Research, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Pharmacology & Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.
Cheng G; Center for Disease Prevention Research, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Free Radical Research Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Biophysics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.
Pan J; Center for Disease Prevention Research, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Pharmacology & Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.
Zielonka J; Center for Disease Prevention Research, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Free Radical Research Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Biophysics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.
Xiong D; Center for Disease Prevention Research, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Pharmacology & Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.
Myers CR; Center for Disease Prevention Research, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Pharmacology & Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Free Radical Research Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.
Feng L; Center for Disease Prevention Research, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Pharmacology & Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.
Shin SS; Life Science R&D Center, Osong, Cheongju, South Korea.
Kim YH; Life Science R&D Center, Osong, Cheongju, South Korea.
Bui D; College of Pharmacy, University of Houston, Houston, TX, 77204-5037, USA.
Hu M; College of Pharmacy, University of Houston, Houston, TX, 77204-5037, USA.
Bennett B; Department of Physics, Marquette University, Milwaukee, WI, 53233, USA.
Schmainda K; Department of Biophysics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.
Wang Y; Center for Disease Prevention Research, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Pharmacology & Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.
Kalyanaraman B; Center for Disease Prevention Research, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Free Radical Research Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Biophysics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.
You M; Center for Disease Prevention Research, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA. .; Department of Pharmacology & Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA. .; Pokaż więcej
Źródło:: Cell communication and signaling : CCS [Cell Commun Signal] 2020 Apr 07; Vol. 18 (1), pp. 58. Date of Electronic Publication: 2020 Apr 07.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms:: Antineoplastic Agents, Phytogenic*/pharmacology
Antineoplastic Agents, Phytogenic*/therapeutic use
Biphenyl Compounds*/pharmacology
Biphenyl Compounds*/therapeutic use
Lignans*/pharmacology
Lignans*/therapeutic use
Plant Extracts*/pharmacology
Plant Extracts*/therapeutic use
Magnolia/*chemistry
Mouth Neoplasms/*prevention & control
Animals ; Cell Line, Tumor ; Drug Evaluation, Preclinical ; Female ; Humans ; Mice ; Mice, Nude ; Mitochondria/metabolism ; Reactive Oxygen Species

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Skocz do pozycji: 3.

Tytuł:: Inhibition potential of phenolic constituents from the aerial parts of Tetrastigma hemsleyanum against soluble epoxide hydrolase and nitric oxide synthase.
Autorzy:: Wang CY; a College of Pharmacy, Chungnam National University , Daejeon , Korea.
Lee S; a College of Pharmacy, Chungnam National University , Daejeon , Korea.
Jang HJ; b Immunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology , Jeongeup-si , Jeonbuk , Korea.
Su XD; a College of Pharmacy, Chungnam National University , Daejeon , Korea.
Wang HS; c State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University , Guilin , People's Republic of China.
Kim YH; a College of Pharmacy, Chungnam National University , Daejeon , Korea.
Yang SY; a College of Pharmacy, Chungnam National University , Daejeon , Korea.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2019 Dec; Vol. 34 (1), pp. 753-760.
Typ publikacji:: Journal Article
MeSH Terms:: Epoxide Hydrolases/*antagonists & inhibitors
Nitric Oxide Synthase/*antagonists & inhibitors
Phenols/*pharmacology
Plant Components, Aerial/*chemistry
Plant Extracts/*pharmacology
Vitaceae/*chemistry
Animals ; Cell Survival/drug effects ; Cells, Cultured ; Dose-Response Relationship, Drug ; Epoxide Hydrolases/metabolism ; Mice ; Models, Molecular ; Molecular Structure ; Nitric Oxide Synthase/metabolism ; Phenols/chemistry ; Phenols/isolation & purification ; Plant Extracts/chemistry ; Plant Extracts/isolation & purification ; RAW 264.7 Cells ; Solubility ; Structure-Activity Relationship

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Skocz do pozycji: 4.

Tytuł:: Changes of Phytochemical Components (Urushiols, Polyphenols, Gallotannins) and Antioxidant Capacity during Fomitella fraxinea ⁻Mediated Fermentation of Toxicodendron vernicifluum Bark.
Autorzy:: Kim DH; Department of Food Science and Biotechnology, Chonbuk National University, Jeonju 54896, Jeonbuk, Korea. .
Kim MJ; Department of Food Science and Biotechnology, Chonbuk National University, Jeonju 54896, Jeonbuk, Korea. .
Kim DW; Department of Food Science and Biotechnology, Chonbuk National University, Jeonju 54896, Jeonbuk, Korea. .
Kim GY; Department of Food Science and Biotechnology, Chonbuk National University, Jeonju 54896, Jeonbuk, Korea. .
Kim JK; Department of Food Science and Biotechnology, Chonbuk National University, Jeonju 54896, Jeonbuk, Korea. .
Gebru YA; Department of Food Science and Biotechnology, Chonbuk National University, Jeonju 54896, Jeonbuk, Korea. .
Choi HS; Department of Agriculture and Fisheries Processing, Korea National College of Agriculture and Fisheries, Jeonju 54874, Jeonbuk, Korea. .
Kim YH; Department of Food Science and Biotechnology, Chonbuk National University, Jeonju 54896, Jeonbuk, Korea. .
Kim MK; Department of Food Science and Biotechnology, Chonbuk National University, Jeonju 54896, Jeonbuk, Korea. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2019 Feb 14; Vol. 24 (4). Date of Electronic Publication: 2019 Feb 14.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidants/*chemistry
Phytochemicals/*chemistry
Plant Extracts/*chemistry
Toxicodendron/*chemistry
Benzothiazoles/chemistry ; Catechols/chemistry ; Fermentation ; Hydrolyzable Tannins/chemistry ; Plant Bark/chemistry ; Plant Bark/microbiology ; Plant Extracts/pharmacology ; Polyphenols/chemistry ; Polyporaceae/chemistry ; Polyporaceae/metabolism ; Sulfonic Acids/chemistry

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Skocz do pozycji: 5.

Tytuł:: Comparison of Bioactive Compounds and Antioxidant Activities of Maclura tricuspidata Fruit Extracts at Different Maturity Stages.
Autorzy:: Kim DW; Department of Food Science and Technology, Chonbuk National University, Jeonju 54896, Jeonbuk, Korea. .
Lee WJ; Department of Food Science and Technology, Chonbuk National University, Jeonju 54896, Jeonbuk, Korea. .
Asmelash Gebru Y; Department of Food Science and Technology, Chonbuk National University, Jeonju 54896, Jeonbuk, Korea. .
Choi HS; Fermented Food Science Division, National Institute of Agricultural Sciences, Rural Development Administration (RDA), Wanju 55365, Jeonbuk, Korea. .
Yeo SH; Fermented Food Science Division, National Institute of Agricultural Sciences, Rural Development Administration (RDA), Wanju 55365, Jeonbuk, Korea. .
Jeong YJ; Agency for Korea National Food Cluster (AnFC), Iksan 54576, Jeonbuk, Korea. .
Kim S; Department of Food Science and Biotechnology, Gwangju University, Gwangju 61743, Korea. .
Kim YH; Department of Food Science and Technology, Chonbuk National University, Jeonju 54896, Jeonbuk, Korea. .
Kim MK; Department of Food Science and Technology, Chonbuk National University, Jeonju 54896, Jeonbuk, Korea. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2019 Feb 04; Vol. 24 (3). Date of Electronic Publication: 2019 Feb 04.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidants/*pharmacology
Fruit/*chemistry
Maclura/*chemistry
Plant Extracts/*pharmacology
Antioxidants/chemistry ; Carotenoids/analysis ; Carotenoids/chemistry ; Chromatography, High Pressure Liquid ; Fruit/growth & development ; Furans/chemistry ; Maclura/growth & development ; Plant Extracts/chemistry ; Polyphenols/chemistry ; Reproducibility of Results ; Solvents/chemistry ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

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Skocz do pozycji: 6.

Tytuł:: Isolation of Two New Compounds and Other Constituents from Leaves of Piper crocatum and Study of Their Soluble Epoxide Hydrolase Activities.
Autorzy:: Li HX; College of Pharmacy, Chungnam National University, Daejeon 34134, Korea. .
Yang SY; College of Pharmacy, Chungnam National University, Daejeon 34134, Korea. .
Kim YH; College of Pharmacy, Chungnam National University, Daejeon 34134, Korea. .
Li W; Korean Medicine (KM) Application Center, Korea Institute of Oriental Medicine, Daegu 41062, Korea. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2019 Jan 30; Vol. 24 (3). Date of Electronic Publication: 2019 Jan 30.
Typ publikacji:: Journal Article
MeSH Terms:: Epoxide Hydrolases/*chemistry
Piper/*chemistry
Plant Extracts/*chemistry
Plant Leaves/*chemistry
Enzyme Activation ; Epoxide Hydrolases/antagonists & inhibitors ; Epoxide Hydrolases/metabolism ; Magnetic Resonance Spectroscopy ; Molecular Structure ; Solubility ; Spectrum Analysis

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Skocz do pozycji: 7.

Tytuł:: Sicyos angulatus ameliorates acute liver injury by inhibiting oxidative stress via upregulation of anti-oxidant enzymes.
Autorzy:: Kim HY; a Laboratory Animal Resource Center , Korea Research Institute of Bioscience and Biotechnology (KRIBB) , Daejeon , Republic of Korea.; c Department of Food and Nutrition , Chungnam National University , Daejeon , Republic of Korea.
Noh JR; a Laboratory Animal Resource Center , Korea Research Institute of Bioscience and Biotechnology (KRIBB) , Daejeon , Republic of Korea.
Moon SJ; a Laboratory Animal Resource Center , Korea Research Institute of Bioscience and Biotechnology (KRIBB) , Daejeon , Republic of Korea.
Choi DH; a Laboratory Animal Resource Center , Korea Research Institute of Bioscience and Biotechnology (KRIBB) , Daejeon , Republic of Korea.
Kim YH; a Laboratory Animal Resource Center , Korea Research Institute of Bioscience and Biotechnology (KRIBB) , Daejeon , Republic of Korea.; b University of Science and Technology , Daejeon , Republic of Korea.
Kim KS; a Laboratory Animal Resource Center , Korea Research Institute of Bioscience and Biotechnology (KRIBB) , Daejeon , Republic of Korea.; b University of Science and Technology , Daejeon , Republic of Korea.
Yook HS; c Department of Food and Nutrition , Chungnam National University , Daejeon , Republic of Korea.
An JP; d Research Institute of Pharmaceutical Sciences, College of Pharmacy , Korea Bioactive Natural Material Bank, Seoul National University , Seoul , Republic of Korea.
Oh WK; d Research Institute of Pharmaceutical Sciences, College of Pharmacy , Korea Bioactive Natural Material Bank, Seoul National University , Seoul , Republic of Korea.
Hwang JH; a Laboratory Animal Resource Center , Korea Research Institute of Bioscience and Biotechnology (KRIBB) , Daejeon , Republic of Korea.; b University of Science and Technology , Daejeon , Republic of Korea.
Lee CH; a Laboratory Animal Resource Center , Korea Research Institute of Bioscience and Biotechnology (KRIBB) , Daejeon , Republic of Korea.; b University of Science and Technology , Daejeon , Republic of Korea.; Pokaż więcej
Źródło:: Redox report : communications in free radical research [Redox Rep] 2018 Dec; Vol. 23 (1), pp. 206-212.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidants/*metabolism
Liver/*drug effects
Liver/*injuries
Loranthaceae/*chemistry
Plant Extracts/*pharmacology
Alanine Transaminase/metabolism ; Animals ; Aspartate Aminotransferases/metabolism ; Glutathione/metabolism ; Glutathione Peroxidase/metabolism ; Lipid Peroxidation/drug effects ; Liver/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism ; Superoxide Dismutase/metabolism ; tert-Butylhydroperoxide/metabolism

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Skocz do pozycji: 8.

Tytuł:: Kushenol A and 8-prenylkaempferol, tyrosinase inhibitors, derived from Sophora flavescens.
Autorzy:: Kim JH; a Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute , Jeongeup , Republic of Korea.
Cho IS; b Department of Horticultural and Crop Environment , National Institute of Horticultural and Herbal Science, RDA , Wanju , Republic of Korea.
So YK; a Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute , Jeongeup , Republic of Korea.
Kim HH; b Department of Horticultural and Crop Environment , National Institute of Horticultural and Herbal Science, RDA , Wanju , Republic of Korea.
Kim YH; c College of Pharmacy , Chungnam National University , Daejeon , Republic of Korea.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2018 Dec; Vol. 33 (1), pp. 1048-1054.
Typ publikacji:: Journal Article
MeSH Terms:: Enzyme Inhibitors/*pharmacology
Flavonoids/*pharmacology
Kaempferols/*pharmacology
Monophenol Monooxygenase/*antagonists & inhibitors
Plant Extracts/*pharmacology
Sophora/*chemistry
Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/isolation & purification ; Flavonoids/chemistry ; Flavonoids/isolation & purification ; Hep G2 Cells ; Humans ; Kaempferols/chemistry ; Kaempferols/isolation & purification ; Kinetics ; Molecular Docking Simulation ; Molecular Structure ; Monophenol Monooxygenase/metabolism ; Plant Extracts/chemistry ; Plant Extracts/isolation & purification ; Plant Roots/chemistry ; Reactive Oxygen Species/analysis ; Reactive Oxygen Species/antagonists & inhibitors ; Reactive Oxygen Species/metabolism ; Structure-Activity Relationship ; Tumor Cells, Cultured

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Skocz do pozycji: 9.

Tytuł:: Antidepressant-Like and Neuroprotective Effects of Ethanol Extract from the Root Bark of Hibiscus syriacus L.
Autorzy:: Kim YH; Clinical Medicine Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea.
Im AR; Herbal Medicine Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea.
Park BK; Clinical Medicine Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea.
Paek SH; Department of Life Science, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul 04107, Republic of Korea.
Choi G; Herbal Medicine Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea.
Kim YR; Clinical Medicine Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea.
Whang WK; Pharmaceutical Botany Laboratory, College of Pharmacy, Chung-Ang University, 47 Heukseok-ro, Dongjak-gu, Seoul 06974, Republic of Korea.
Lee KH; Pharmaceutical Botany Laboratory, College of Pharmacy, Chung-Ang University, 47 Heukseok-ro, Dongjak-gu, Seoul 06974, Republic of Korea.
Oh SE; Department of Biological Sciences, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Republic of Korea.
Lee MY; Clinical Medicine Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2018 Nov 19; Vol. 2018, pp. 7383869. Date of Electronic Publication: 2018 Nov 19 (Print Publication: 2018).
Typ publikacji:: Journal Article
MeSH Terms:: Antidepressive Agents/*pharmacology
Depression/*drug therapy
Hibiscus/*chemistry
Neuroprotective Agents/*pharmacology
Plant Extracts/*pharmacology
Animals ; Behavior, Animal/drug effects ; Brain/drug effects ; Brain/metabolism ; Brain-Derived Neurotrophic Factor/metabolism ; Cell Survival/drug effects ; Cells, Cultured ; Corticosterone/metabolism ; Cyclic AMP Response Element-Binding Protein/metabolism ; Depression/metabolism ; Disease Models, Animal ; Ethanol/chemistry ; Hindlimb Suspension/physiology ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Plant Bark/chemistry ; Plant Roots/chemistry ; Stress, Psychological/drug therapy ; Stress, Psychological/metabolism ; Swimming/physiology

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Skocz do pozycji: 10.

Tytuł:: Identification of Anti-Melanogenesis Constituents from Morus alba L. Leaves.
Autorzy:: Li HX; College of Pharmacy, Chungnam National University, Daejeon 34134, Korea. .
Park JU; College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Gwangju 61186, Korea. .
Su XD; College of Pharmacy, Chungnam National University, Daejeon 34134, Korea. .
Kim KT; Division of Applied Bioengineering, College of Engineering, Dong-Eui University, Busan 47340, Korea. .
Kang JS; College of Pharmacy, Chungnam National University, Daejeon 34134, Korea. .
Kim YR; College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Gwangju 61186, Korea. .
Kim YH; College of Pharmacy, Chungnam National University, Daejeon 34134, Korea. .
Yang SY; College of Pharmacy, Chungnam National University, Daejeon 34134, Korea. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2018 Oct 08; Vol. 23 (10). Date of Electronic Publication: 2018 Oct 08.
Typ publikacji:: Journal Article
MeSH Terms:: Melanins/*biosynthesis
Monophenol Monooxygenase/*antagonists & inhibitors
Morus/*chemistry
Plant Extracts/*pharmacokinetics
Animals ; Cyclic AMP Response Element-Binding Protein/genetics ; Cyclic AMP Response Element-Binding Protein/metabolism ; Dose-Response Relationship, Drug ; Melanins/metabolism ; Melanoma, Experimental/metabolism ; Mice ; Monophenol Monooxygenase/metabolism ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Plant Leaves/chemistry ; alpha-MSH/genetics

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Skocz do pozycji: 11.

Tytuł:: Antidepressant Effect of Fraxinus rhynchophylla Hance Extract in a Mouse Model of Chronic Stress-Induced Depression.
Autorzy:: Kim YR; Clinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.
Park BK; Clinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.
Kim YH; Clinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.
Shim I; Department of Physiology, School of Medicine, Kyung Hee University, 1 Kyungheedae-ro, Dongdaemun-gu, Seoul 02454, Republic of Korea.
Kang IC; Department of Biological Science, College of Life and Health Sciences, Hoseo University, Asan 31499, Republic of Korea.
Lee MY; Clinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2018 Jul 03; Vol. 2018, pp. 8249563. Date of Electronic Publication: 2018 Jul 03 (Print Publication: 2018).
Typ publikacji:: Journal Article
MeSH Terms:: Stress, Psychological*
Antidepressive Agents/*pharmacology
Depression/*drug therapy
Fraxinus/*chemistry
Plant Extracts/*pharmacology
Animals ; Brain-Derived Neurotrophic Factor ; Depression/psychology ; Disease Models, Animal ; Hippocampus ; Male ; Mice

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Skocz do pozycji: 12.

Tytuł:: Antioxidant and Anti-Osteoporosis Activities of Chemical Constituents of the Stems of Zanthoxylum piperitum.
Autorzy:: Yang SY; College of Pharmacy, Chungnam National University, Daejeon 34134, Republic of Korea. .
Lee SH; Department of Food and Nutrition, Hannam University, Daejeon 34054, Republic of Korea. .
Tai BH; Institute of Marine Biochemistry (IMBC), Vietnam Academy of Science and Technology (VAST), Hanoi 10000, Vietnam. .
Jang HD; Department of Food and Nutrition, Hannam University, Daejeon 34054, Republic of Korea. .
Kim YH; College of Pharmacy, Chungnam National University, Daejeon 34134, Republic of Korea. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2018 Feb 18; Vol. 23 (2). Date of Electronic Publication: 2018 Feb 18.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidants/*chemistry
Osteoporosis/*drug therapy
Plant Extracts/*chemistry
Zanthoxylum/*chemistry
Antioxidants/isolation & purification ; Antioxidants/therapeutic use ; Flavonoids/chemistry ; Humans ; Lignans/chemistry ; Oxygen Radical Absorbance Capacity ; Peroxides/chemistry ; Phenols/chemistry ; Plant Extracts/therapeutic use ; Tartrate-Resistant Acid Phosphatase/chemistry

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Skocz do pozycji: 13.

Tytuł:: Chemical Constituents from Apios americana and Their Inhibitory Activity on Tyrosinase.
Autorzy:: Kim JH; Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup, Jeollabuk-do 56212, Korea. .
Kim HY; Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup, Jeollabuk-do 56212, Korea. .
Kang SY; Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup, Jeollabuk-do 56212, Korea. .
Kim JB; Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup, Jeollabuk-do 56212, Korea. .
Kim YH; College of Pharmacy, Chungnam National University, Daejeon 34134, Korea. .
Jin CH; Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup, Jeollabuk-do 56212, Korea. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2018 Jan 22; Vol. 23 (1). Date of Electronic Publication: 2018 Jan 22.
Typ publikacji:: Journal Article
MeSH Terms:: Enzyme Inhibitors/*chemistry
Enzyme Inhibitors/*pharmacology
Fabaceae/*chemistry
Monophenol Monooxygenase/*chemistry
Plant Extracts/*chemistry
Plant Extracts/*pharmacology
Dose-Response Relationship, Drug ; Enzyme Activation/drug effects ; Enzyme Inhibitors/isolation & purification ; Kinetics ; Models, Molecular ; Molecular Conformation ; Molecular Structure ; Monophenol Monooxygenase/antagonists & inhibitors ; Phytochemicals/chemistry ; Plant Extracts/isolation & purification ; Structure-Activity Relationship

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Skocz do pozycji: 14.

Tytuł:: Pre‑treatment with Chrysanthemum indicum Linné extract protects pyramidal neurons from transient cerebral ischemia via increasing antioxidants in the gerbil hippocampal CA1 region.
Autorzy:: Kim IH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Lee TK; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Cho JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Park JH; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Ahn JH; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Shin BN; Department of Physiology, College of Medicine, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Chen BH; Department of Histology and Embryology, Institute of Neuroscience, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Tae HJ; Bio‑Safety Research Institute, College of Veterinary Medicine, Chonbuk National University, Iksan, Jeollabuk‑do 54596, Republic of Korea.
Kim YH; Department of Surgery, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Kim YM; Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2017 Jul; Vol. 16 (1), pp. 133-142. Date of Electronic Publication: 2017 May 17.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidants/*metabolism
CA1 Region, Hippocampal/*metabolism
Chrysanthemum/*chemistry
Ischemic Attack, Transient/*metabolism
Neuroprotective Agents/*pharmacology
Plant Extracts/*pharmacology
Pyramidal Cells/*drug effects
Pyramidal Cells/*metabolism
Animals ; Biomarkers ; Catalase/metabolism ; Disease Models, Animal ; Gerbillinae ; Glutathione Peroxidase/metabolism ; Immunohistochemistry ; Ischemic Attack, Transient/drug therapy ; Ischemic Attack, Transient/pathology ; Male ; Superoxide Dismutase-1/metabolism

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Skocz do pozycji: 15.

Tytuł:: Effect of isosecotanapartholide isolated from Artemisia princeps Pampanini on IL‑33 production and STAT‑1 activation in HaCaT keratinocytes.
Autorzy:: Oh CT; Department of Dermatology, Chung‑Ang University College of Medicine, Seoul 156‑755, Republic of Korea.
Jang YJ; Department of Dermatology, Chung‑Ang University College of Medicine, Seoul 156‑755, Republic of Korea.
Kwon TR; Department of Dermatology, Chung‑Ang University College of Medicine, Seoul 156‑755, Republic of Korea.
Im S; Department of Dermatology, Chung‑Ang University College of Medicine, Seoul 156‑755, Republic of Korea.
Kim SR; Department of Dermatology, Chung‑Ang University College of Medicine, Seoul 156‑755, Republic of Korea.
Seok J; Department of Dermatology, Chung‑Ang University College of Medicine, Seoul 156‑755, Republic of Korea.
Kim GY; Department of Biotechnology R&D, SK Bioland Corporation, Cheongju, North Chungcheong ASI/KR/KS001, Republic of Korea.
Kim YH; Department of Biotechnology R&D, SK Bioland Corporation, Cheongju, North Chungcheong ASI/KR/KS001, Republic of Korea.
Mun SK; Department of Otolaryngology Head and Neck Surgery, Chung‑Ang University College of Medicine, Seoul 156‑755, Republic of Korea.
Kim BJ; Department of Dermatology, Chung‑Ang University College of Medicine, Seoul 156‑755, Republic of Korea.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2017 May; Vol. 15 (5), pp. 2681-2688. Date of Electronic Publication: 2017 Mar 09.
Typ publikacji:: Journal Article
MeSH Terms:: Artemisia/*chemistry
Interleukin-33/*biosynthesis
Keratinocytes/*metabolism
Plant Extracts/*pharmacology
STAT1 Transcription Factor/*metabolism
Signal Transduction/*drug effects
Cell Line ; Humans ; Keratinocytes/cytology ; Plant Extracts/chemistry

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Skocz do pozycji: 16.

Tytuł:: Malva verticillata seed extracts upregulate the Wnt pathway in human dermal papilla cells.
Autorzy:: Lee EY; Department of Biotechnology, CHA University, Seongnam, Korea.
Choi EJ; Department of Biotechnology, CHA University, Seongnam, Korea.
Kim JA; College of Pharmacy, Kyungpook National University, Daegu, Korea.
Hwang YL; OBM Laboratory, Daejeon, Korea.
Kim CD; Department of Dermatology, School of Medicine, Chungnam National University, Daejeon, Korea.
Lee MH; OBM Laboratory, Daejeon, Korea.
Roh SS; OBM Laboratory, Daejeon, Korea.
Kim YH; College of Pharmacy, Chungnam National University, Daejeon, Korea.
Han I; Department of Neurosurgery, CHA University, CHA Bundang Medical Center, Seongnam, Korea.
Kang S; Department of Biotechnology, CHA University, Seongnam, Korea.; Pokaż więcej
Źródło:: International journal of cosmetic science [Int J Cosmet Sci] 2016 Apr; Vol. 38 (2), pp. 148-54. Date of Electronic Publication: 2015 Aug 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Malva/*embryology
Plant Extracts/*pharmacology
Seeds/*chemistry
Up-Regulation/*drug effects
Wnt Proteins/*metabolism
Cells, Cultured ; Humans

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Skocz do pozycji: 17.

Tytuł:: Soluble epoxide hydrolase inhibitory components from Rheum undulatum and in silico approach.
Autorzy:: Jo AR; a College of Pharmacy, Chungnam National University , Daejeon , Republic of Korea.
Kim JH; b Department of Horticultural Environment , National Institute of Horticultural and Herbal Science, RDA , Wanju-Gun, Republic of Korea , and.
Yan XT; c Shaanxi Key Laboratory of Natural Products & Chemical Biology , College of Science, Northwest A & F University , Yangling , Shaanxi , China.
Yang SY; a College of Pharmacy, Chungnam National University , Daejeon , Republic of Korea.
Kim YH; a College of Pharmacy, Chungnam National University , Daejeon , Republic of Korea.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2016; Vol. 31 (sup2), pp. 70-78. Date of Electronic Publication: 2016 Aug 23.
Typ publikacji:: Journal Article
MeSH Terms:: Enzyme Inhibitors/*pharmacology
Epoxide Hydrolases/*antagonists & inhibitors
Plant Extracts/*pharmacology
Plant Structures/*chemistry
Rheum/*chemistry
Catalytic Domain/drug effects ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/isolation & purification ; Epoxide Hydrolases/metabolism ; Humans ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Molecular Structure ; Plant Extracts/chemistry ; Plant Extracts/isolation & purification ; Solubility ; Structure-Activity Relationship

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Skocz do pozycji: 18.

Tytuł:: In vitro anti-inflammatory components isolated from the carnivorous plant Nepenthes mirabilis (Lour.) Rafarin.
Autorzy:: Thao NP; a College of Pharmacy, Chungnam National University , Daejeon , Republic of Korea .; b Institute of Marine Biochemistry (IMBC), Vietnam Academy of Science and Technology (VAST), Cau Giay , Hanoi , Vietnam , and.
Luyen BT; a College of Pharmacy, Chungnam National University , Daejeon , Republic of Korea .
Koo JE; c School of Medicine, Brain Korea 21 PLUS Program, Institute of Medical Science, Jeju National University , Jeju , Republic of Korea.
Kim S; c School of Medicine, Brain Korea 21 PLUS Program, Institute of Medical Science, Jeju National University , Jeju , Republic of Korea.
Koh YS; c School of Medicine, Brain Korea 21 PLUS Program, Institute of Medical Science, Jeju National University , Jeju , Republic of Korea.
Thanh NV; b Institute of Marine Biochemistry (IMBC), Vietnam Academy of Science and Technology (VAST), Cau Giay , Hanoi , Vietnam , and.
Cuong NX; b Institute of Marine Biochemistry (IMBC), Vietnam Academy of Science and Technology (VAST), Cau Giay , Hanoi , Vietnam , and.
Kiem PV; b Institute of Marine Biochemistry (IMBC), Vietnam Academy of Science and Technology (VAST), Cau Giay , Hanoi , Vietnam , and.
Minh CV; b Institute of Marine Biochemistry (IMBC), Vietnam Academy of Science and Technology (VAST), Cau Giay , Hanoi , Vietnam , and.
Kim YH; a College of Pharmacy, Chungnam National University , Daejeon , Republic of Korea .; Pokaż więcej
Źródło:: Pharmaceutical biology [Pharm Biol] 2016; Vol. 54 (4), pp. 588-94. Date of Electronic Publication: 2015 Jul 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Mirabilis*
Anti-Inflammatory Agents/*isolation & purification
Bone Marrow Cells/*drug effects
Inflammation Mediators/*antagonists & inhibitors
Plant Extracts/*isolation & purification
Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/pharmacology ; Bone Marrow Cells/physiology ; Cell Survival/drug effects ; Cell Survival/physiology ; Cells, Cultured ; Humans ; Inflammation Mediators/physiology ; Plant Extracts/chemistry ; Plant Extracts/pharmacology

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Skocz do pozycji: 19.

Tytuł:: Soluble Epoxide Hydrolase Inhibitory Activity of Selaginellin Derivatives from Selaginella tamariscina.
Autorzy:: Kim JH; College of Pharmacy, Chungnam National University, Daejeon 305-764, Korea. .; Department of Horticultural Environment, National Institute of Horticultural and Herbal Science, RDA, Wanju-gun, Jeollabuk-do 595-890, Korea. .
Cho CW; College of Pharmacy, Chungnam National University, Daejeon 305-764, Korea. .
Tai BH; College of Pharmacy, Chungnam National University, Daejeon 305-764, Korea. .; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, 18-Hoang Quoc Viet, Caugiay, Hanoi 364-545, Vietnam. .
Yang SY; College of Pharmacy, Chungnam National University, Daejeon 305-764, Korea. .
Choi GS; Department of Horticultural Environment, National Institute of Horticultural and Herbal Science, RDA, Wanju-gun, Jeollabuk-do 595-890, Korea. .
Kang JS; College of Pharmacy, Chungnam National University, Daejeon 305-764, Korea. .
Kim YH; College of Pharmacy, Chungnam National University, Daejeon 305-764, Korea. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2015 Dec 02; Vol. 20 (12), pp. 21405-14. Date of Electronic Publication: 2015 Dec 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cyclohexanones/*pharmacology
Enzyme Inhibitors/*pharmacology
Epoxide Hydrolases/*antagonists & inhibitors
Plant Extracts/*pharmacology
Selaginellaceae/*chemistry
Cyclohexanones/chemistry ; Enzyme Inhibitors/chemistry ; Humans ; Molecular Structure

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Skocz do pozycji: 20.

Tytuł:: Cinidium officinale and its Bioactive Compound, Butylidenephthalide, Inhibit Laser-Induced Choroidal Neovascularization in a Rat Model.
Autorzy:: Lee YM; College of Pharmacy, Chungnam National University, Daejeon 34134, Korea. .; Korean Medicine Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea. .
Lee YR; Korean Medicine Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea. .
Kim JS; Korean Medicine Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea. .
Kim YH; College of Pharmacy, Chungnam National University, Daejeon 34134, Korea. .
Kim J; Korean Medicine Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2015 Nov 19; Vol. 20 (11), pp. 20699-708. Date of Electronic Publication: 2015 Nov 19.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Choroidal Neovascularization/*pathology
Phthalic Anhydrides/*pharmacology
Plant Extracts/*pharmacology
Angiogenesis Inhibitors/chemistry ; Angiogenesis Inhibitors/pharmacology ; Animals ; Chemokine CCL2/genetics ; Chemokine CCL2/metabolism ; Choroidal Neovascularization/drug therapy ; Choroidal Neovascularization/etiology ; Choroidal Neovascularization/metabolism ; Disease Models, Animal ; Gene Expression Regulation/drug effects ; Insulin-Like Growth Factor Binding Protein 1/genetics ; Insulin-Like Growth Factor Binding Protein 1/metabolism ; Lasers/adverse effects ; Macrophages/drug effects ; Macrophages/metabolism ; Macrophages/pathology ; Phthalic Anhydrides/chemistry ; Plant Extracts/chemistry ; Rats ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism

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