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Wyszukujesz frazę ""Kinesin"" wg kryterium: Temat


Tytuł :
Novel photochromic inhibitor for mitotic kinesin Eg5 which forms multiple isomerization states.
Autorzy :
Alrazi IM; Department of Biosciences, Graduate School of Science and Engineering, Soka University, 1-236 Tangi-cho, Hachioji, Tokyo 192-8577, Japan.
Sadakane K; Department of Biosciences, Graduate School of Science and Engineering, Soka University, 1-236 Tangi-cho, Hachioji, Tokyo 192-8577, Japan.
Maruta S; Department of Biosciences, Graduate School of Science and Engineering, Soka University, 1-236 Tangi-cho, Hachioji, Tokyo 192-8577, Japan.
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Źródło :
Journal of biochemistry [J Biochem] 2021 Oct 11; Vol. 170 (2), pp. 229-237.
Typ publikacji :
Journal Article
MeSH Terms :
Mitosis*
Azo Compounds/*pharmacology
Benzopyrans/*pharmacology
Indoles/*pharmacology
Kinesin/*antagonists & inhibitors
Kinesin/*metabolism
Nitro Compounds/*pharmacology
Adenosine Triphosphatases/metabolism ; Azo Compounds/chemistry ; Azo Compounds/metabolism ; Benzopyrans/chemistry ; Benzopyrans/metabolism ; Cell Division/drug effects ; Cell Movement/drug effects ; Humans ; Indoles/chemistry ; Indoles/metabolism ; Isomerism ; Kinesin/chemistry ; Light ; Luminescent Agents/pharmacology ; Microtubules/metabolism ; Nitro Compounds/chemistry ; Nitro Compounds/metabolism ; Protein Binding
Czasopismo naukowe
Tytuł :
Inhibitor library screening identifies ispinesib as a new potential chemotherapeutic agent for pancreatic cancers.
Autorzy :
Murase Y; Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Ono H; Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Ogawa K; Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Yoshioka R; Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Ishikawa Y; Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Ueda H; Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Akahoshi K; Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Ban D; Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Kudo A; Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Tanaka S; Division of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Tanabe M; Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
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Źródło :
Cancer science [Cancer Sci] 2021 Nov; Vol. 112 (11), pp. 4641-4654. Date of Electronic Publication: 2021 Oct 02.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Benzamides/*pharmacology
Kinesin/*antagonists & inhibitors
Pancreatic Neoplasms/*drug therapy
Quinazolines/*pharmacology
Analysis of Variance ; Animals ; Apoptosis ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Disease-Free Survival ; Drug Discovery ; Female ; Gene Silencing ; Humans ; Kinesin/genetics ; Kinesin/metabolism ; Libraries, Special ; Metaphase/drug effects ; Mice ; Mice, Nude ; Neoplasm Proteins/antagonists & inhibitors ; Neoplasm Proteins/metabolism ; Pancreatic Neoplasms/metabolism ; Pancreatic Neoplasms/mortality ; Pancreatic Neoplasms/pathology ; Tumor Burden/drug effects ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
KIF18b-dependent hypomethylation of PARPBP gene promoter enhances oxaliplatin resistance in colorectal cancer.
Autorzy :
Hong B; Pharmaceutical Preparation Section, Sanmen People's Hospital of Zhejiang Province, Sanmen, 317100, China. Electronic address: .
Lu R; Department of Laboratory Medicine, Taizhou Enze Medical Center (Group) Enze Hospital, Taizhou, 318050, China. Electronic address: .
Lou W; Department of Integrated Traditional & Western Medicine, Sanmen Hospital of TCM, Sanmen, 317100, China. Electronic address: .
Bao Y; Pharmaceutical Preparation Section, Sanmen People's Hospital of Zhejiang Province, Sanmen, 317100, China. Electronic address: .
Qiao L; Central Laboratory, The Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University, Xuzhou, 221100, China. Electronic address: .
Hu Y; Central Laboratory, Sanmen People's Hospital of Zhejiang Province, Sanmen, 317100, China. Electronic address: .
Liu K; Pharmaceutical Preparation Section, Sanmen People's Hospital of Zhejiang Province, Sanmen, 317100, China. Electronic address: .
Chen J; Department of Gastroenterology, Sanmen People's Hospital of Zhejiang Province, Sanmen, 317100, China. Electronic address: .
Bao D; Central Laboratory, Sanmen People's Hospital of Zhejiang Province, Sanmen, 317100, China. Electronic address: .
Ye M; Department of General Surgery, Sanmen People's Hospital of Zhejiang Province, Sanmen, 317100, China. Electronic address: .
Fang Z; Central Laboratory, Sanmen People's Hospital of Zhejiang Province, Sanmen, 317100, China. Electronic address: .
Gong C; Central Laboratory, The Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University, Xuzhou, 221100, China. Electronic address: .
Zhang X; Pharmaceutical Preparation Section, Sanmen People's Hospital of Zhejiang Province, Sanmen, 317100, China. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2021 Oct 15; Vol. 407 (2), pp. 112827. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Methylation*
Gene Expression Regulation, Neoplastic*
Colorectal Neoplasms/*drug therapy
DNA-Binding Proteins/*genetics
Drug Resistance, Neoplasm/*genetics
Kinesin/*metabolism
Oxaliplatin/*pharmacology
Aged ; Antineoplastic Agents/pharmacology ; Apoptosis ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Cell Proliferation ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; Female ; Humans ; Kinesin/genetics ; Male ; Prognosis ; Promoter Regions, Genetic ; Survival Rate ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Dynamics of kinesin motor proteins under longitudinal and sideways loads.
Autorzy :
Xie P; Key Laboratory of Soft Matter Physics, Institute of Physics, Chinese Academy of Science, Beijing 100190, China.
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Źródło :
Journal of theoretical biology [J Theor Biol] 2021 Dec 07; Vol. 530, pp. 110879. Date of Electronic Publication: 2021 Aug 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dyneins*
Kinesin*/metabolism
Microtubules/metabolism ; Molecular Motor Proteins ; Myosins
Czasopismo naukowe
Tytuł :
Dynamic Dissection of Dynein and Kinesin-1 Cooperatively Mediated Intercellular Transport of Porcine Epidemic Diarrhea Coronavirus along Microtubule Using Single Virus Tracking.
Autorzy :
Hou W; Joint International Research Laboratory of Animal Health and Food Safety of Ministry of Education & Single Molecule Nanometry Laboratory (Sinmolab), Nanjing Agricultural University , Nanjing, Jiangsu, China.
Kang W; Joint International Research Laboratory of Animal Health and Food Safety of Ministry of Education & Single Molecule Nanometry Laboratory (Sinmolab), Nanjing Agricultural University , Nanjing, Jiangsu, China.
Li Y; Joint International Research Laboratory of Animal Health and Food Safety of Ministry of Education & Single Molecule Nanometry Laboratory (Sinmolab), Nanjing Agricultural University , Nanjing, Jiangsu, China.
Shan Y; Joint International Research Laboratory of Animal Health and Food Safety of Ministry of Education & Single Molecule Nanometry Laboratory (Sinmolab), Nanjing Agricultural University , Nanjing, Jiangsu, China.
Wang S; Joint International Research Laboratory of Animal Health and Food Safety of Ministry of Education & Single Molecule Nanometry Laboratory (Sinmolab), Nanjing Agricultural University , Nanjing, Jiangsu, China.; Computational Optics Laboratory, Jiangnan University , Wuxi, Jiangsu, China.
Liu F; Joint International Research Laboratory of Animal Health and Food Safety of Ministry of Education & Single Molecule Nanometry Laboratory (Sinmolab), Nanjing Agricultural University , Nanjing, Jiangsu, China.
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Źródło :
Virulence [Virulence] 2021 Dec; Vol. 12 (1), pp. 615-629.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dyneins/*metabolism
Kinesin/*metabolism
Microtubules/*metabolism
Porcine epidemic diarrhea virus/*physiology
Animals ; Biological Transport ; Chlorocebus aethiops ; Cytoplasm/metabolism ; Dyneins/antagonists & inhibitors ; Kinesin/genetics ; Membrane Fusion ; Microscopy, Fluorescence ; RNA, Small Interfering ; Vero Cells
Czasopismo naukowe
Tytuł :
Role and mechanism of intraflagellar transport in mammalian spermiogenesis.
Autorzy :
Ge TT; Jiangsu Key Laboratory of Experimental & Translational Non-coding RNA Research, Department of Histology and Embryology, School of Medicine, Yangzhou University, Yangzhou 225009, China.
Yuan L; Jiangsu Key Laboratory of Experimental & Translational Non-coding RNA Research, Department of Histology and Embryology, School of Medicine, Yangzhou University, Yangzhou 225009, China.
Xu WH; Jiangsu Key Laboratory of Experimental & Translational Non-coding RNA Research, Department of Histology and Embryology, School of Medicine, Yangzhou University, Yangzhou 225009, China.
Zheng Y; Jiangsu Key Laboratory of Experimental & Translational Non-coding RNA Research, Department of Histology and Embryology, School of Medicine, Yangzhou University, Yangzhou 225009, China.
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Źródło :
Yi chuan = Hereditas [Yi Chuan] 2021 Nov 20; Vol. 43 (11), pp. 1038-1049.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Flagella*/metabolism
Kinesin*/metabolism
Animals ; Biological Transport ; Cilia/metabolism ; Male ; Mice ; Spermatogenesis
Czasopismo naukowe
Tytuł :
Heterotrimeric Kinesin II is required for flagellar assembly and elongation of nuclear morphology during spermiogenesis in Schmidtea mediterranea.
Autorzy :
Christman DA; Department of Biological Sciences, Wright State University, 3640 Colonel Glenn Highway, Dayton, OH, 45435-0001, USA.
Curry HN; Department of Biological Sciences, Wright State University, 3640 Colonel Glenn Highway, Dayton, OH, 45435-0001, USA.
Rouhana L; Department of Biological Sciences, Wright State University, 3640 Colonel Glenn Highway, Dayton, OH, 45435-0001, USA. Electronic address: .
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Źródło :
Developmental biology [Dev Biol] 2021 Sep; Vol. 477, pp. 191-204. Date of Electronic Publication: 2021 Jun 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Kinesin/*physiology
Planarians/*cytology
Sperm Tail/*physiology
Spermatogenesis/*physiology
Animals ; Cell Nucleus/ultrastructure ; Cytoskeletal Proteins/physiology ; Gene Knockdown Techniques ; Kinesin/chemistry ; Kinesin/genetics ; Male ; RNA Interference ; Sperm Head/ultrastructure ; Sperm Tail/ultrastructure
Czasopismo naukowe
Tytuł :
Inducible manipulation of motor-cargo interaction using engineered kinesin motors.
Autorzy :
Hummel JJA; Cell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht 3584 CH, The Netherlands.
Hoogenraad CC; Cell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht 3584 CH, The Netherlands.; Department of Neuroscience, Genentech, Inc., South San Francisco, CA 94080, USA.
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Źródło :
Journal of cell science [J Cell Sci] 2021 Aug 01; Vol. 134 (15). Date of Electronic Publication: 2021 Aug 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Axons*/metabolism
Kinesin*/genetics
Kinesin*/metabolism
Biological Transport ; Neurons/metabolism ; Transport Vesicles/metabolism
Czasopismo naukowe
Tytuł :
KIF4A knockdown suppresses ovarian cancer cell proliferation and induces apoptosis by downregulating BUB1 expression.
Autorzy :
Jin W; Reproductive Medicine Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Ye L; Department of Intensive Care Unit, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2021 Jul; Vol. 24 (1). Date of Electronic Publication: 2021 May 20.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Cell Proliferation/*drug effects
Kinesin/*genetics
Kinesin/*metabolism
Ovarian Neoplasms/*genetics
Ovarian Neoplasms/*metabolism
Protein-Serine-Threonine Kinases/*genetics
Protein-Serine-Threonine Kinases/*metabolism
Cell Cycle ; Cell Line, Tumor ; Cell Movement ; Cell Survival ; Down-Regulation ; Female ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Humans ; Kinesin/pharmacology ; Wound Healing
Czasopismo naukowe
Tytuł :
Molecular characterization, dynamic transcription, and potential function of KIF3A/KIF3B during spermiogenesis in Opsariichthys bidens.
Autorzy :
Lin C; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, People's Republic of China.
Tang D; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, People's Republic of China.
Gao X; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, People's Republic of China.
Jiang H; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, People's Republic of China.
Du C; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, People's Republic of China.
Zhu J; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, People's Republic of China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Sep 25; Vol. 798, pp. 145795. Date of Electronic Publication: 2021 Jun 24.
Typ publikacji :
Journal Article
MeSH Terms :
Cyprinidae/*physiology
Kinesin/*physiology
Spermatogenesis/*physiology
Animals ; Cyprinidae/genetics ; Kinesin/chemistry ; Kinesin/genetics ; Male ; Microtubules/metabolism ; Mitochondria/metabolism ; Phylogeny ; Protein Conformation ; RNA, Messenger/metabolism ; Sequence Alignment ; Sequence Analysis, DNA ; Sperm Tail/physiology ; Spermatids/physiology ; Spermatids/ultrastructure ; Spermatogenesis/genetics ; Testis/metabolism ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Differential regulation of single microtubules and bundles by a three-protein module.
Autorzy :
Mani N; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.
Jiang S; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.
Neary AE; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA.
Wijeratne SS; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.
Subramanian R; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA. .; Department of Genetics, Harvard Medical School, Boston, MA, USA. .
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Źródło :
Nature chemical biology [Nat Chem Biol] 2021 Sep; Vol. 17 (9), pp. 964-974. Date of Electronic Publication: 2021 Jun 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Cycle Proteins/*metabolism
Kinesin/*metabolism
Microtubule-Associated Proteins/*metabolism
Microtubules/*metabolism
Cell Cycle Proteins/genetics ; Cell Cycle Proteins/isolation & purification ; Humans ; Kinesin/genetics ; Kinesin/isolation & purification ; Microtubule-Associated Proteins/genetics ; Microtubule-Associated Proteins/isolation & purification
Czasopismo naukowe
Tytuł :
Kinesin Nanomotors Mediated Trafficking of NMDA-Loaded Cargo as A Novel Target in Chronic Pain.
Autorzy :
Uniyal A; Neuroscience and Pain Research Laboratory, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology B.H.U., Varanasi 221005, India.
Thakur V; Neuroscience and Pain Research Laboratory, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology B.H.U., Varanasi 221005, India.
Rani M; Neuroscience and Pain Research Laboratory, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology B.H.U., Varanasi 221005, India.
Tiwari V; Neuroscience and Pain Research Laboratory, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology B.H.U., Varanasi 221005, India.
Akhilesh; Neuroscience and Pain Research Laboratory, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology B.H.U., Varanasi 221005, India.
Gadepalli A; Neuroscience and Pain Research Laboratory, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology B.H.U., Varanasi 221005, India.
Ummadisetty O; Neuroscience and Pain Research Laboratory, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology B.H.U., Varanasi 221005, India.
Modi A; Neuroscience and Pain Research Laboratory, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology B.H.U., Varanasi 221005, India.
Tiwari V; Neuroscience and Pain Research Laboratory, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology B.H.U., Varanasi 221005, India.
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Źródło :
ACS chemical neuroscience [ACS Chem Neurosci] 2021 Aug 18; Vol. 12 (16), pp. 2956-2963. Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chronic Pain*/drug therapy
Kinesin*/metabolism
Humans ; Neurons/metabolism ; Protein Transport ; Receptors, N-Methyl-D-Aspartate/metabolism
Czasopismo naukowe
Tytuł :
Intracellular functions and motile properties of bi-directional kinesin-5 Cin8 are regulated by neck linker docking.
Autorzy :
Goldstein-Levitin A; Department of Chemistry, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Pandey H; Department of Chemistry, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Allhuzaeel K; Department of Chemistry, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Kass I; Department of Chemistry, Ben-Gurion University of the Negev, Beer-Sheva, Israel.; InterX LTD, Ramat-Gan, Israel.
Gheber L; Department of Chemistry, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
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Źródło :
ELife [Elife] 2021 Aug 13; Vol. 10. Date of Electronic Publication: 2021 Aug 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Fungal*
Kinesin/*genetics
Saccharomyces cerevisiae/*genetics
Saccharomyces cerevisiae/*physiology
Saccharomyces cerevisiae Proteins/*metabolism
Hydrogen Bonding ; Kinesin/chemistry ; Kinesin/classification ; Kinesin/metabolism ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/genetics ; Spindle Apparatus/metabolism
Czasopismo naukowe
Tytuł :
A minus-end directed kinesin motor directs gravitropism in Physcomitrella patens.
Autorzy :
Li Y; State Key Laboratory of Protein and Plant Gene Research, School of Advanced Agricultural Sciences and School of Life Sciences, Peking University, Beijing, China.
Deng Z; Center for Plant Biology, School of Life Sciences, Tsinghua University, Beijing, China.
Kamisugi Y; Centre for Plant Sciences, University of Leeds, Leeds, UK.
Chen Z; Center for Plant Biology, School of Life Sciences, Tsinghua University, Beijing, China.; Tsinghua-Peking Center for Life Sciences, Beijing, China.
Wang J; State Key Laboratory of Protein and Plant Gene Research, School of Advanced Agricultural Sciences and School of Life Sciences, Peking University, Beijing, China.
Han X; State Key Laboratory of Protein and Plant Gene Research, School of Advanced Agricultural Sciences and School of Life Sciences, Peking University, Beijing, China.
Wei Y; State Key Laboratory of Protein and Plant Gene Research, School of Advanced Agricultural Sciences and School of Life Sciences, Peking University, Beijing, China.; Center for Plant Biology, School of Life Sciences, Tsinghua University, Beijing, China.
He H; State Key Laboratory of Protein and Plant Gene Research, School of Advanced Agricultural Sciences and School of Life Sciences, Peking University, Beijing, China.
Terzaghi W; Department of Biology, Wilkes University, Wilkes-Barre, PA, USA.
Cove DJ; Centre for Plant Sciences, University of Leeds, Leeds, UK.
Cuming AC; Centre for Plant Sciences, University of Leeds, Leeds, UK.
Chen H; Center for Plant Biology, School of Life Sciences, Tsinghua University, Beijing, China. .; Tsinghua-Peking Center for Life Sciences, Beijing, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Jul 22; Vol. 12 (1), pp. 4470. Date of Electronic Publication: 2021 Jul 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bryopsida/*physiology
Gravitropism/*physiology
Kinesin/*physiology
Plant Proteins/*physiology
Actin Cytoskeleton/chemistry ; Actin Cytoskeleton/physiology ; Base Sequence ; Bryopsida/genetics ; Chromosome Mapping ; Cytoskeleton/chemistry ; Cytoskeleton/physiology ; DNA, Plant/genetics ; Genes, Plant ; Gravitropism/genetics ; Kinesin/chemistry ; Kinesin/genetics ; Microtubules/chemistry ; Microtubules/physiology ; Mutagenesis ; Mutation ; Plant Proteins/chemistry ; Plant Proteins/genetics ; Plants, Genetically Modified ; Protein Domains
Czasopismo naukowe
Tytuł :
Eg5 as a Prognostic Biomarker and Potential Therapeutic Target for Hepatocellular Carcinoma.
Autorzy :
Shao YY; Graduate Institute of Oncology, National Taiwan University College of Medicine, 1, Sec. 1, Ren'ai Rd., Taipei 100, Taiwan.; Department of Oncology, National Taiwan University Hospital, 7, Chung-Shan S. Rd., Taipei 100, Taiwan.
Sun NY; Graduate Institute of Oncology, National Taiwan University College of Medicine, 1, Sec. 1, Ren'ai Rd., Taipei 100, Taiwan.
Jeng YM; Department of Pathology, National Taiwan University Hospital, 7, Chung-Shan S. Rd., Taipei 100, Taiwan.; Graduate Institute of Pathology, National Taiwan University College of Medicine, 1, Sec. 1, Ren'ai Rd., Taipei 100, Taiwan.
Wu YM; Department of Surgery, National Taiwan University Hospital, 7, Chung-Shan S. Rd., Taipei 100, Taiwan.
Hsu C; Graduate Institute of Oncology, National Taiwan University College of Medicine, 1, Sec. 1, Ren'ai Rd., Taipei 100, Taiwan.; Department of Oncology, National Taiwan University Hospital, 7, Chung-Shan S. Rd., Taipei 100, Taiwan.; Department of Medical Oncology, National Taiwan University Cancer Center, 57, Lane 155, Sec. 3, Keelung Rd., Taipei 106, Taiwan.
Hsu CH; Graduate Institute of Oncology, National Taiwan University College of Medicine, 1, Sec. 1, Ren'ai Rd., Taipei 100, Taiwan.; Department of Oncology, National Taiwan University Hospital, 7, Chung-Shan S. Rd., Taipei 100, Taiwan.; Department of Medical Oncology, National Taiwan University Cancer Center, 57, Lane 155, Sec. 3, Keelung Rd., Taipei 106, Taiwan.
Hsu HC; Department of Pathology, National Taiwan University Hospital, 7, Chung-Shan S. Rd., Taipei 100, Taiwan.; Graduate Institute of Pathology, National Taiwan University College of Medicine, 1, Sec. 1, Ren'ai Rd., Taipei 100, Taiwan.
Cheng AL; Graduate Institute of Oncology, National Taiwan University College of Medicine, 1, Sec. 1, Ren'ai Rd., Taipei 100, Taiwan.; Department of Oncology, National Taiwan University Hospital, 7, Chung-Shan S. Rd., Taipei 100, Taiwan.; Department of Medical Oncology, National Taiwan University Cancer Center, 57, Lane 155, Sec. 3, Keelung Rd., Taipei 106, Taiwan.; Department of Internal Medicine, National Taiwan University Hospital, 7, Chung-Shan S. Rd., Taipei 100, Taiwan.
Lin ZZ; Department of Oncology, National Taiwan University Hospital, 7, Chung-Shan S. Rd., Taipei 100, Taiwan.; Department of Medical Oncology, National Taiwan University Cancer Center, 57, Lane 155, Sec. 3, Keelung Rd., Taipei 106, Taiwan.; Department of Internal Medicine, National Taiwan University Hospital, 7, Chung-Shan S. Rd., Taipei 100, Taiwan.
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Źródło :
Cells [Cells] 2021 Jul 05; Vol. 10 (7). Date of Electronic Publication: 2021 Jul 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor/*metabolism
Carcinoma, Hepatocellular/*metabolism
Kinesin/*metabolism
Liver Neoplasms/*metabolism
Apoptosis ; Carcinoma, Hepatocellular/pathology ; Cell Cycle ; Cell Line, Tumor ; Cell Proliferation ; Cell Survival ; DNA, Neoplasm/metabolism ; Female ; Humans ; Kinesin/antagonists & inhibitors ; Liver Neoplasms/pathology ; Male ; Middle Aged ; Prognosis ; Spindle Apparatus/metabolism ; Survival Analysis
Czasopismo naukowe
Tytuł :
Sequences in the stalk domain regulate auto-inhibition and ciliary tip localization of the immotile kinesin-4 KIF7.
Autorzy :
Blasius TL; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Yue Y; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Prasad R; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Liu X; Department of Anatomy and Structural Biology and Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, New York, NY 10461, USA.
Gennerich A; Department of Anatomy and Structural Biology and Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, New York, NY 10461, USA.
Verhey KJ; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
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Źródło :
Journal of cell science [J Cell Sci] 2021 Jul 01; Vol. 134 (13). Date of Electronic Publication: 2021 Jul 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cilia*
Kinesin*/genetics
Axoneme ; Hedgehog Proteins ; Humans ; Microtubules
Czasopismo naukowe
Tytuł :
Effects of Gold Nanoparticles on the Stepping Trajectories of Kinesin.
Autorzy :
Hasnain S; Department of Chemistry, The University of Texas at Austin, Austin 78712, Texas, United States.
Mugnai ML; Department of Chemistry, The University of Texas at Austin, Austin 78712, Texas, United States.
Thirumalai D; Department of Chemistry, The University of Texas at Austin, Austin 78712, Texas, United States.
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Źródło :
The journal of physical chemistry. B [J Phys Chem B] 2021 Sep 23; Vol. 125 (37), pp. 10432-10444. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Kinesin*
Metal Nanoparticles*
Diffusion ; Gold ; Microtubules
Czasopismo naukowe
Tytuł :
KIF15 upregulation promotes leiomyosarcoma cell growth via promoting USP15-mediated DEK deubiquitylation.
Autorzy :
Ge W; Foot and Ankle Surgery, Luoyang Orthopedic Hospital of Henan Province, Orthopedic Hospital of Henan Province, Luoyang, Henan, China.
Chen Y; Center of Traumatic Orthopedics, People's Liberation Army 990 Hospital, Xinyang, Henan, China.
Guo Y; Foot and Ankle Surgery, Luoyang Orthopedic Hospital of Henan Province, Orthopedic Hospital of Henan Province, Luoyang, Henan, China.
Zhao D; Foot and Ankle Surgery, Luoyang Orthopedic Hospital of Henan Province, Orthopedic Hospital of Henan Province, Luoyang, Henan, China.
Mu L; Foot and Ankle Surgery, Luoyang Orthopedic Hospital of Henan Province, Orthopedic Hospital of Henan Province, Luoyang, Henan, China.
Zhang K; Foot and Ankle Surgery, Luoyang Orthopedic Hospital of Henan Province, Orthopedic Hospital of Henan Province, Luoyang, Henan, China.
Zhuo W; Department of Orthopedics and Traumatology, 960 Hospital of PLA, Jinan, Shandong, China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Sep 17; Vol. 570, pp. 117-124. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Ubiquitination*
Chromosomal Proteins, Non-Histone/*metabolism
Kinesin/*genetics
Leiomyosarcoma/*genetics
Leiomyosarcoma/*pathology
Oncogene Proteins/*metabolism
Poly-ADP-Ribose Binding Proteins/*metabolism
Ubiquitin-Specific Proteases/*metabolism
Up-Regulation/*genetics
Cell Line, Tumor ; Cell Proliferation/genetics ; Humans ; Kinesin/metabolism ; Proteasome Endopeptidase Complex/metabolism ; Protein Binding ; Protein Stability ; Proteolysis
Czasopismo naukowe
Tytuł :
Prognostic Impact and Functional Annotations of KIF11 and KIF14 Expression in Patients with Colorectal Cancer.
Autorzy :
Neska-Długosz I; Department of Clinical Pathomorphology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 85-094 Bydgoszcz, Poland.
Buchholz K; Department of Clinical Pathomorphology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 85-094 Bydgoszcz, Poland.; Department of Histology and Embryology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 85-092 Bydgoszcz, Poland.
Durślewicz J; Department of Clinical Pathomorphology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 85-094 Bydgoszcz, Poland.
Gagat M; Department of Histology and Embryology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 85-092 Bydgoszcz, Poland.
Grzanka D; Department of Clinical Pathomorphology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 85-094 Bydgoszcz, Poland.
Tojek K; Department of General, Colorectal and Oncological Surgery, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 85-168 Bydgoszcz, Poland.
Klimaszewska-Wiśniewska A; Department of Clinical Pathomorphology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 85-094 Bydgoszcz, Poland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 08; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 08.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor*
Gene Expression Regulation, Neoplastic*
Colorectal Neoplasms/*genetics
Kinesin/*genetics
Oncogene Proteins/*genetics
Aged ; Aged, 80 and over ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/mortality ; Colorectal Neoplasms/pathology ; Computational Biology ; Female ; Gene Expression Profiling ; Genomic Instability ; Humans ; Immunohistochemistry ; Kaplan-Meier Estimate ; Kinesin/metabolism ; Male ; Middle Aged ; Neoplasm Staging ; Oncogene Proteins/metabolism ; Prognosis ; Proportional Hazards Models
Czasopismo naukowe
Tytuł :
Wnt signaling establishes the microtubule polarity in neurons through regulation of Kinesin-13.
Autorzy :
Puri D; Department of Cellular and Molecular Neuroscience, National Brain Research Centre, Manesar, Gurgaon, Haryana, India.
Ponniah K; Department of Cellular and Molecular Neuroscience, National Brain Research Centre, Manesar, Gurgaon, Haryana, India.
Biswas K; Department of Cellular and Molecular Neuroscience, National Brain Research Centre, Manesar, Gurgaon, Haryana, India.
Basu A; Department of Cellular and Molecular Neuroscience, National Brain Research Centre, Manesar, Gurgaon, Haryana, India.
Dey S; Department of Cellular and Molecular Neuroscience, National Brain Research Centre, Manesar, Gurgaon, Haryana, India.
Lundquist EA; Department of Molecular Biosciences, University of Kansas, Lawrence, KS.
Ghosh-Roy A; Department of Cellular and Molecular Neuroscience, National Brain Research Centre, Manesar, Gurgaon, Haryana, India.
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Źródło :
The Journal of cell biology [J Cell Biol] 2021 Sep 06; Vol. 220 (9). Date of Electronic Publication: 2021 Jun 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Caenorhabditis elegans/*genetics
Caenorhabditis elegans Proteins/*genetics
Kinesin/*genetics
Microtubule-Associated Proteins/*genetics
Microtubules/*metabolism
Neurogenesis/*genetics
Wnt Signaling Pathway/*genetics
Animals ; Axons/metabolism ; Axons/ultrastructure ; Biological Transport ; Caenorhabditis elegans/cytology ; Caenorhabditis elegans/metabolism ; Caenorhabditis elegans Proteins/metabolism ; Cell Differentiation ; Cell Polarity/genetics ; Dendrites/metabolism ; Dendrites/ultrastructure ; Gene Expression Regulation ; Kinesin/metabolism ; Microtubule-Associated Proteins/metabolism ; Microtubules/ultrastructure ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; rac GTP-Binding Proteins/genetics ; rac GTP-Binding Proteins/metabolism ; rho GTP-Binding Proteins/genetics ; rho GTP-Binding Proteins/metabolism ; rho-Associated Kinases/genetics ; rho-Associated Kinases/metabolism
Czasopismo naukowe

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