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Tytuł :
B 1 and B 2 kinin receptor blockade improves psoriasis-like disease.
Autorzy :
Soley BDS; Department of Pharmacology, Federal University of Parana, Curitiba, Brazil.
Silva LM; Department of Biophysics, Federal University of São Paulo, São Paulo, Brazil.
Mendes DAGB; Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis, Brazil.
Báfica A; Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis, Brazil.
Pesquero JB; Department of Biophysics, Federal University of São Paulo, São Paulo, Brazil.
Bader M; Max Delbrück Center for Molecular Medicine (MDC), Berlin, Germany.; Institute for Biology, University of Lübeck, Germany.; Charité University Medicine, Berlin, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Berlin, Germany.
Witherden DA; Immunology and Microbiology, Scripps Research Institute, La Jolla, California, USA.
Havran WL; Immunology and Microbiology, Scripps Research Institute, La Jolla, California, USA.
Calixto JB; Center of Innovation and Preclinical Studies (CIENP), Florianópolis, Brazil.
Otuki MF; Department of Pharmacology, Federal University of Parana, Curitiba, Brazil.
Cabrini DA; Department of Pharmacology, Federal University of Parana, Curitiba, Brazil.
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Źródło :
British journal of pharmacology [Br J Pharmacol] 2020 Aug; Vol. 177 (15), pp. 3535-3551. Date of Electronic Publication: 2020 May 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Kinins*
Psoriasis*/drug therapy
Animals ; CD8-Positive T-Lymphocytes ; Mice ; Mice, Inbred C57BL ; Receptor, Bradykinin B1 ; Receptor, Bradykinin B2
Czasopismo naukowe
Tytuł :
Myocardial angiogenesis induced by exercise training involves a regulatory mechanism mediated by kinin receptors.
Autorzy :
Shen M; Department of Rehabilitation Medicin, The People's Hospital of Longhua District, Shenzhen, Guangdong Province, China.
Yu M; Department of Rehabilitation Medicine, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning Province, China.
Qiu C; Department of Rehabilitation Medicin, The People's Hospital of Longhua District, Shenzhen, Guangdong Province, China.
Zhang G; Department of Electrocardiogram, The People's Hospital of Longhua District, Shenzhen, Guangdong Province, China.
Li J; Department of Rehabilitation Medicine, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning Province, China.
Fang W; Department of Nursing, The People's Hospital of Longhua District, Shenzhen, Guangdong Province, China.
Wang Q; Department of Rehabilitation Medicin, The People's Hospital of Longhua District, Shenzhen, Guangdong Province, China.
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Źródło :
Clinical and experimental hypertension (New York, N.Y. : 1993) [Clin Exp Hypertens] 2021 Jul 04; Vol. 43 (5), pp. 408-415. Date of Electronic Publication: 2021 Mar 09.
Typ publikacji :
Journal Article
MeSH Terms :
Neovascularization, Physiologic*
Physical Conditioning, Animal*
Myocardium/*metabolism
Receptor, Bradykinin B1/*metabolism
Receptor, Bradykinin B2/*metabolism
Animals ; Capillaries/metabolism ; Kinins/metabolism ; Male ; Myocytes, Cardiac/metabolism ; Nitric Oxide Synthase Type III/genetics ; Nitric Oxide Synthase Type III/metabolism ; Platelet Endothelial Cell Adhesion Molecule-1/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats, Wistar ; Receptor, Bradykinin B1/genetics ; Receptor, Bradykinin B2/genetics ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Tytuł :
Role of Matricellular CCN Proteins in Skeletal Muscle: Focus on CCN2/CTGF and Its Regulation by Vasoactive Peptides.
Autorzy :
Rebolledo DL; Centro de Envejecimiento y Regeneración, CARE Chile UC, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile.; Centro de Excelencia en Biomedicina de Magallanes (CEBIMA), Universidad de Magallanes, Punta Arenas 6213515, Chile.
Acuña MJ; Centro de Envejecimiento y Regeneración, CARE Chile UC, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile.; Centro Integrativo de Biología y Química Aplicada (CIBQA), Universidad Bernardo O Higgins, Santiago 8370854, Chile.
Brandan E; Centro de Envejecimiento y Regeneración, CARE Chile UC, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile.; Departamento de Biología Celular y Molecular, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile.; Fundación Ciencia & Vida, Santiago 7810000, Chile.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 15; Vol. 22 (10). Date of Electronic Publication: 2021 May 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Connective Tissue Growth Factor/*metabolism
Muscle, Skeletal/*physiology
Peptides/*metabolism
Animals ; Gene Expression Regulation, Developmental ; Humans ; Kinins/metabolism ; Multigene Family ; Muscle Proteins/metabolism ; Muscle, Skeletal/blood supply ; Muscle, Skeletal/pathology ; Muscular Atrophy/metabolism ; Muscular Atrophy/pathology ; Muscular Diseases/metabolism ; Muscular Diseases/pathology ; Regeneration ; Renin-Angiotensin System
Czasopismo naukowe
Tytuł :
A random small molecule library screen identifies novel antagonists of the kinin receptor from the cattle fever tick, Rhipicephalus microplus (Acari: Ixodidae).
Autorzy :
Xiong C; Department of Entomology, Texas A&M University, College Station, TX, USA.
Baker D; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, USA.
Pietrantonio PV; Department of Entomology, Texas A&M University, College Station, TX, USA.
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Źródło :
Pest management science [Pest Manag Sci] 2021 May; Vol. 77 (5), pp. 2238-2251. Date of Electronic Publication: 2021 Feb 02.
Typ publikacji :
Journal Article
MeSH Terms :
Acaricides*/pharmacology
Babesiosis*
Ixodidae*
Rhipicephalus*/genetics
Animals ; Cattle ; Cricetinae ; Female ; Kinins ; Mosquito Vectors
Czasopismo naukowe
Tytuł :
The kallikrein-kinin pathway as a mechanism for auto-control of brown adipose tissue activity.
Autorzy :
Peyrou M; Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina, Universitat de Barcelona (IBUB) and CIBER Fisiopatología de la Obesidad y Nutrición, Avda Diagonal 643, 08028, Barcelona, Spain.
Cereijo R; Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina, Universitat de Barcelona (IBUB) and CIBER Fisiopatología de la Obesidad y Nutrición, Avda Diagonal 643, 08028, Barcelona, Spain.
Quesada-López T; Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina, Universitat de Barcelona (IBUB) and CIBER Fisiopatología de la Obesidad y Nutrición, Avda Diagonal 643, 08028, Barcelona, Spain.
Campderrós L; Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina, Universitat de Barcelona (IBUB) and CIBER Fisiopatología de la Obesidad y Nutrición, Avda Diagonal 643, 08028, Barcelona, Spain.
Gavaldà-Navarro A; Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina, Universitat de Barcelona (IBUB) and CIBER Fisiopatología de la Obesidad y Nutrición, Avda Diagonal 643, 08028, Barcelona, Spain.
Liñares-Pose L; Grupo NeurObesity, Departamento de Fisiología, CiMUS, Universidade de Santiago de Compostela-Instituto de Investigación Sanitaria and CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), 15706, Santiago de Compostela, Spain.
Kaschina E; Charité Universitäts medizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universitätzu Berlin, and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research (CCR), Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), Partner site Berlin, Berlin, Germany.
Unger T; CARIM-School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.
López M; Grupo NeurObesity, Departamento de Fisiología, CiMUS, Universidade de Santiago de Compostela-Instituto de Investigación Sanitaria and CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), 15706, Santiago de Compostela, Spain.
Giralt M; Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina, Universitat de Barcelona (IBUB) and CIBER Fisiopatología de la Obesidad y Nutrición, Avda Diagonal 643, 08028, Barcelona, Spain.
Villarroya F; Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina, Universitat de Barcelona (IBUB) and CIBER Fisiopatología de la Obesidad y Nutrición, Avda Diagonal 643, 08028, Barcelona, Spain. .
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Źródło :
Nature communications [Nat Commun] 2020 May 01; Vol. 11 (1), pp. 2132. Date of Electronic Publication: 2020 May 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipose Tissue, Brown/*metabolism
Kallikreins/*metabolism
Kinins/*metabolism
Animals ; Bradykinin/genetics ; Bradykinin/metabolism ; Endocrine System/metabolism ; Fluorescent Antibody Technique ; Kallikreins/genetics ; Kininogens/genetics ; Kininogens/metabolism ; Kinins/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Real-Time Polymerase Chain Reaction ; Signal Transduction/genetics ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
SARS-CoV-2 suppresses anticoagulant and fibrinolytic gene expression in the lung.
Autorzy :
Mast AE; Versiti Blood Research Institute, Department of Cell Biology Neurobiology and Anatomy Medical College of Wisconsin, Milwaukee, United States.
Wolberg AS; Department of Pathology and Laboratory Medicine and UNC Blood Research Center, Chapel Hill, United States.
Gailani D; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, United States.
Garvin MR; Oak Ridge National Laboratory, Biosciences Division, Oak Ridge, United States.
Alvarez C; Oak Ridge National Laboratory, Biosciences Division, Oak Ridge, United States.
Miller JI; Oak Ridge National Laboratory, Biosciences Division, Oak Ridge, United States.
Aronow B; University of Tennessee Knoxville, The Bredesen Center for Interdisciplinary Research and Graduate Education, Knoxville, United States.; Biomedical Informatics, Cincinnati Children's Hospital Research Foundation, Cincinnati, United States.; University of Cincinnati, Cincinnati, United States.
Jacobson D; Oak Ridge National Laboratory, Biosciences Division, Oak Ridge, United States.; University of Tennessee Knoxville, The Bredesen Center for Interdisciplinary Research and Graduate Education, Knoxville, United States.; University of Tennessee Knoxville, Department of Psychology, Knoxville, United States.
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Źródło :
ELife [Elife] 2021 Mar 08; Vol. 10. Date of Electronic Publication: 2021 Mar 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
SARS-CoV-2*
Blood Coagulation/*genetics
COVID-19/*pathology
Fibrin/*genetics
Lung/*pathology
Anticoagulants/metabolism ; Bronchoalveolar Lavage Fluid ; COVID-19/genetics ; COVID-19/metabolism ; Endothelial Protein C Receptor/genetics ; Endothelial Protein C Receptor/metabolism ; Fibrin/metabolism ; Gene Expression ; Humans ; Kallikrein-Kinin System/genetics ; Kallikreins/genetics ; Kallikreins/metabolism ; Kinins/genetics ; Kinins/metabolism ; Lung/metabolism ; RNA, Messenger/metabolism ; Sequence Analysis, RNA ; Thrombomodulin/genetics ; Thrombomodulin/metabolism ; Urokinase-Type Plasminogen Activator/genetics ; Urokinase-Type Plasminogen Activator/metabolism
Czasopismo naukowe
Tytuł :
Kinin B1 receptor: a potential therapeutic target in sepsis-induced vascular hyperpermeability.
Autorzy :
Ruiz S; Department of Anesthesiology and Intensive Care, Rangueil Hospital-University Hospital of Toulouse, 1 Avenue du Professeur Jean Poulhès TSA 50032, 31059, Toulouse Cedex 9, France. .; Institute of Metabolic and Cardiovascular Diseases, INSERM/UPS UMR, 1048-I2MC, Equipe 3, Paul Sabatier University, Toulouse, France. .
Vardon-Bounes F; Department of Anesthesiology and Intensive Care, Rangueil Hospital-University Hospital of Toulouse, 1 Avenue du Professeur Jean Poulhès TSA 50032, 31059, Toulouse Cedex 9, France.; Institute of Metabolic and Cardiovascular Diseases, INSERM/UPS UMR, 1048-I2MC, Equipe 3, Paul Sabatier University, Toulouse, France.
Buléon M; Institute of Metabolic and Cardiovascular Diseases, INSERM/UPS UMR, 1048-I2MC, Equipe 3, Paul Sabatier University, Toulouse, France.
Guilbeau-Frugier C; Institute of Metabolic and Cardiovascular Diseases, INSERM/UPS UMR, 1048-I2MC, Equipe 3, Paul Sabatier University, Toulouse, France.; Department of Forensic Medicine, Rangueil Hospital-University Hospital of Toulouse, 1 Avenue du Professeur Jean Poulhès TSA 50032, 31059, Toulouse Cedex 9, France.; Biological Electron Microscopy Center, Rangueil Faculty of Medicine, Toulouse University, Toulouse, France.
Séguelas MH; Institute of Metabolic and Cardiovascular Diseases, INSERM/UPS UMR, 1048-I2MC, Equipe 3, Paul Sabatier University, Toulouse, France.
Conil JM; Department of Anesthesiology and Intensive Care, Rangueil Hospital-University Hospital of Toulouse, 1 Avenue du Professeur Jean Poulhès TSA 50032, 31059, Toulouse Cedex 9, France.
Girolami JP; Institute of Metabolic and Cardiovascular Diseases, INSERM/UPS UMR, 1048-I2MC, Equipe 3, Paul Sabatier University, Toulouse, France.
Tack I; Institute of Metabolic and Cardiovascular Diseases, INSERM/UPS UMR, 1048-I2MC, Equipe 3, Paul Sabatier University, Toulouse, France.; Department of Physiology, Rangueil Hospital-University Hospital of Toulouse, 1 Avenue du Professeur Jean Poulhès TSA 50032, 31059, Toulouse Cedex 9, France.
Minville V; Department of Anesthesiology and Intensive Care, Rangueil Hospital-University Hospital of Toulouse, 1 Avenue du Professeur Jean Poulhès TSA 50032, 31059, Toulouse Cedex 9, France.; Institute of Metabolic and Cardiovascular Diseases, INSERM/UPS UMR, 1048-I2MC, Equipe 3, Paul Sabatier University, Toulouse, France.
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Źródło :
Journal of translational medicine [J Transl Med] 2020 Apr 19; Vol. 18 (1), pp. 174. Date of Electronic Publication: 2020 Apr 19.
Typ publikacji :
Journal Article
MeSH Terms :
Kinins*
Sepsis*/complications
Sepsis*/drug therapy
Animals ; Male ; Mice ; Prospective Studies ; Receptor, Bradykinin B1 ; Receptor, Bradykinin B2
Czasopismo naukowe
Tytuł :
Kinins and chymase: the forgotten components of the renin-angiotensin system and their implications in COVID-19 disease.
Autorzy :
Abassi Z; Department of Physiology and Biophysics, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.; Department of Laboratory Medicine, Rambam Health Care Campus, Haifa, Israel.
Skorecki K; The Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Hamo-Giladi DB; Department of Physiology and Biophysics, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Kruzel-Davila E; Department of Nephrology, Rambam Health Care Campus, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Heyman SN; Department of Medicine, Hadassah Hebrew University Hospital, Jerusalem, Israel.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2021 Mar 01; Vol. 320 (3), pp. L422-L429. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Renin-Angiotensin System*
COVID-19/*pathology
Chymases/*metabolism
Kinins/*metabolism
SARS-CoV-2/*isolation & purification
COVID-19/metabolism ; COVID-19/virology ; Humans
Czasopismo naukowe
Tytuł :
Serpin targets in hemostasis/kinin formation.
Autorzy :
Schmaier AH
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Źródło :
Blood [Blood] 2019 Nov 07; Vol. 134 (19), pp. 1566-1568.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Comment
MeSH Terms :
Hemostasis*
Kinins*
Czasopismo naukowe
Tytuł :
Physiological effects of biostable kinin and CAPA analogs in the Chagas disease vector, Rhodnius prolixus.
Autorzy :
Sangha V; Department of Biology, University of Toronto Mississauga, Mississauga, ON, Canada. Electronic address: .
Nachman RJ; Insect Control and Cotton Disease Research, Southern Plains Agricultural Research Centre, U.S Department of Agriculture, College Station, TX, 77845, USA.
Lange A; Department of Biology, University of Toronto Mississauga, Mississauga, ON, Canada.
Orchard I; Department of Biology, University of Toronto Mississauga, Mississauga, ON, Canada.
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Źródło :
Insect biochemistry and molecular biology [Insect Biochem Mol Biol] 2019 Nov; Vol. 114, pp. 103223. Date of Electronic Publication: 2019 Aug 26.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Insect Control*
Insect Vectors*
Kinins*
Neuropeptides*
Rhodnius*
Animals ; Chagas Disease/prevention & control ; Female ; Gastrointestinal Motility/drug effects ; In Vitro Techniques ; Male ; Malpighian Tubules/drug effects
Czasopismo naukowe
Tytuł :
The role of kallikrein-kinin and renin-angiotensin systems in COVID-19 infection.
Autorzy :
Carvalho PR; Universidade Federal do Rio de Janeiro, Instituto de Ciências Biomédicas, Laboratório de Farmacologia da Dor e da Inflamação, Rio de Janeiro, Brazil.
Sirois P; Laval University, Quebec, Canada.
Fernandes PD; Universidade Federal do Rio de Janeiro, Instituto de Ciências Biomédicas, Laboratório de Farmacologia da Dor e da Inflamação, Rio de Janeiro, Brazil. Electronic address: .
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Źródło :
Peptides [Peptides] 2021 Jan; Vol. 135, pp. 170428. Date of Electronic Publication: 2020 Oct 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
COVID-19/*physiopathology
Kallikreins/*metabolism
Kinins/*metabolism
Renin-Angiotensin System/*physiology
SARS-CoV-2/*pathogenicity
Animals ; Antiviral Agents/pharmacology ; COVID-19/drug therapy ; COVID-19/immunology ; COVID-19/metabolism ; COVID-19/transmission ; Drug Repositioning ; Host-Pathogen Interactions ; Humans ; Renin/metabolism ; SARS-CoV-2/genetics ; Virus Internalization
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Assessment of neuropeptide binding sites and the impact of biostable kinin and CAP2b analogue treatment on aphid (Myzus persicae and Macrosiphum rosae) stress tolerance.
Autorzy :
Alford L; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Marley R; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Dornan A; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Pierre JS; UMR 6553 ECOBIO, Centre National de la Recherche Scientifique, Université de Rennes I, Rennes Cedex, France.
Dow JA; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Nachman RJ; Insect Control and Cotton Disease Research Unit, Southern Plains Agricultural Research Center, U.S. Department of Agriculture, College Station, Texas, USA.
Davies SA; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
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Źródło :
Pest management science [Pest Manag Sci] 2019 Jun; Vol. 75 (6), pp. 1750-1759. Date of Electronic Publication: 2019 Mar 21.
Typ publikacji :
Journal Article
MeSH Terms :
Aphids/*drug effects
Aphids/*physiology
Kinins/*chemistry
Kinins/*pharmacology
Neuropeptides/*chemistry
Neuropeptides/*pharmacology
Oligopeptides/*chemistry
Oligopeptides/*pharmacology
Pyrrolidonecarboxylic Acid/*analogs & derivatives
Stress, Physiological/*drug effects
Animals ; Binding Sites ; Heat-Shock Response/drug effects ; Kinins/metabolism ; Neuropeptides/metabolism ; Oligopeptides/metabolism ; Pyrrolidonecarboxylic Acid/chemistry ; Pyrrolidonecarboxylic Acid/metabolism ; Pyrrolidonecarboxylic Acid/pharmacology ; Receptors, Neuropeptide/metabolism
Czasopismo naukowe
Tytuł :
Kinins and nitric oxide in patients with chronic chagas disease and systemic arterial hypertension.
Autorzy :
Dellalibera-Joviliano R; Department of Medicine, UNAERP Medical School, University of Ribeirão Preto, Campus Ribeirão Preto, Brazil. Electronic address: .
Bestetti RB; Department of Medicine, UNAERP Medical School, University of Ribeirão Preto, Campus Ribeirão Preto, Brazil.
Lopes GS; São Rafael Clinic, Piumhi, Brazil.
Furlan-Daniel R; Department of Medicine, UNAERP Medical School, University of Ribeirão Preto, Campus Ribeirão Preto, Brazil.
Lopes KC; São Rafael Clinic, Piumhi, Brazil.
Faria-Junior M; Department of Medicine, UNAERP Medical School, University of Ribeirão Preto, Campus Ribeirão Preto, Brazil.
Junior NI; Department of Medicine, UNAERP Medical School, University of Ribeirão Preto, Campus Ribeirão Preto, Brazil.
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Źródło :
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology [Cardiovasc Pathol] 2020 Nov - Dec; Vol. 49, pp. 107257. Date of Electronic Publication: 2020 Jun 27.
Typ publikacji :
Journal Article
MeSH Terms :
Arterial Pressure*
Chagas Disease/*blood
Hypertension/*blood
Kinins/*blood
Nitric Oxide/*blood
Aged ; Aged, 80 and over ; Biomarkers/blood ; Brazil/epidemiology ; Case-Control Studies ; Chagas Disease/diagnosis ; Chagas Disease/epidemiology ; Chagas Disease/physiopathology ; Female ; Humans ; Hypertension/diagnosis ; Hypertension/epidemiology ; Hypertension/physiopathology ; Male ; Middle Aged ; Up-Regulation
Czasopismo naukowe
Tytuł :
Helicokinin alters ion transport in the secondary cell-containing region of the Malpighian tubule of the larval cabbage looper Trichoplusia ni.
Autorzy :
Kolosov D; Department of Biology, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1, Canada. Electronic address: .
O'Donnell MJ; Department of Biology, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1, Canada.
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Źródło :
General and comparative endocrinology [Gen Comp Endocrinol] 2019 Jul 01; Vol. 278, pp. 12-24. Date of Electronic Publication: 2018 Jul 20.
Typ publikacji :
Journal Article
MeSH Terms :
Brassica/*parasitology
Kinins/*pharmacology
Lepidoptera/*metabolism
Malpighian Tubules/*cytology
Malpighian Tubules/*metabolism
Amino Acid Sequence ; Animals ; Cell Membrane/drug effects ; Cell Membrane/metabolism ; Diet ; Gene Expression Regulation/drug effects ; Insect Proteins/metabolism ; Ion Transport/drug effects ; Ions/metabolism ; Kinins/chemistry ; Larva/drug effects ; Larva/metabolism ; Lepidoptera/drug effects ; Models, Biological ; Natriuretic Peptides/metabolism ; Phylogeny ; Potassium/metabolism ; Receptors, Cell Surface/genetics ; Receptors, Cell Surface/metabolism ; Sodium/metabolism ; Sodium-Potassium-Exchanging ATPase/metabolism
Czasopismo naukowe
Tytuł :
Evaluation of Aib and PEG-polymer insect kinin analogs on mosquito and tick GPCRs identifies potent new pest management tools with potentially enhanced biostability and bioavailability.
Autorzy :
Xiong C; Department of Entomology, Texas A&M University, College Station, TX 77843, USA.
Kaczmarek K; Insect Control and Cotton Disease Research Unit, Southern Plains Agricultural Research Center, U.S. Department of Agriculture, 2881 F/B Road, College Station, TX 77845, USA; Institute of Organic Chemistry, Lodz University of Technology, 90-924 Lodz, Poland.
Zabrocki J; Insect Control and Cotton Disease Research Unit, Southern Plains Agricultural Research Center, U.S. Department of Agriculture, 2881 F/B Road, College Station, TX 77845, USA; Institute of Organic Chemistry, Lodz University of Technology, 90-924 Lodz, Poland.
Pietrantonio PV; Department of Entomology, Texas A&M University, College Station, TX 77843, USA. Electronic address: .
Nachman RJ; Insect Control and Cotton Disease Research Unit, Southern Plains Agricultural Research Center, U.S. Department of Agriculture, 2881 F/B Road, College Station, TX 77845, USA. Electronic address: .
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Źródło :
General and comparative endocrinology [Gen Comp Endocrinol] 2019 Jul 01; Vol. 278, pp. 58-67. Date of Electronic Publication: 2018 Aug 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Pest Control*
Aedes/*drug effects
Aminoisobutyric Acids/*chemistry
Kinins/*pharmacology
Polyethylene Glycols/*chemistry
Receptors, G-Protein-Coupled/*metabolism
Rhipicephalus/*drug effects
Aedes/metabolism ; Amino Acid Sequence ; Animals ; Biological Availability ; Kinins/chemistry ; Rhipicephalus/metabolism ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Airborne Fine Particles Induce Hematological Effects through Regulating the Crosstalk of the Kallikrein-Kinin, Complement, and Coagulation Systems.
Autorzy :
Jin X; State Key Laboratory of Environmental Chemistry and Ecotoxicology , Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences , Beijing 100085 , PR China.; Institutes of Biomedical Sciences , Shanxi University , Taiyuan 030006 , PR China.
Ma Q; State Key Laboratory of Environmental Chemistry and Ecotoxicology , Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences , Beijing 100085 , PR China.; College of Resources and Environment , University of Chinese Academy of Sciences , Beijing 100049 , PR China.
Sun Z; State Key Laboratory of Environmental Chemistry and Ecotoxicology , Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences , Beijing 100085 , PR China.; College of Resources and Environment , University of Chinese Academy of Sciences , Beijing 100049 , PR China.
Yang X; State Key Laboratory of Environmental Chemistry and Ecotoxicology , Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences , Beijing 100085 , PR China.; College of Resources and Environment , University of Chinese Academy of Sciences , Beijing 100049 , PR China.
Zhou Q; State Key Laboratory of Environmental Chemistry and Ecotoxicology , Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences , Beijing 100085 , PR China.; College of Resources and Environment , University of Chinese Academy of Sciences , Beijing 100049 , PR China.; Institute of Environment and Health , Jianghan University , Wuhan 430056 , PR China.
Qu G; State Key Laboratory of Environmental Chemistry and Ecotoxicology , Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences , Beijing 100085 , PR China.; College of Resources and Environment , University of Chinese Academy of Sciences , Beijing 100049 , PR China.; Institute of Environment and Health , Jianghan University , Wuhan 430056 , PR China.
Liu Q; State Key Laboratory of Environmental Chemistry and Ecotoxicology , Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences , Beijing 100085 , PR China.; College of Resources and Environment , University of Chinese Academy of Sciences , Beijing 100049 , PR China.; Institute of Environment and Health , Jianghan University , Wuhan 430056 , PR China.
Liao C; State Key Laboratory of Environmental Chemistry and Ecotoxicology , Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences , Beijing 100085 , PR China.
Li Z; Institutes of Biomedical Sciences , Shanxi University , Taiyuan 030006 , PR China.
Jiang G; State Key Laboratory of Environmental Chemistry and Ecotoxicology , Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences , Beijing 100085 , PR China.; College of Resources and Environment , University of Chinese Academy of Sciences , Beijing 100049 , PR China.
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Źródło :
Environmental science & technology [Environ Sci Technol] 2019 Mar 05; Vol. 53 (5), pp. 2840-2851. Date of Electronic Publication: 2019 Feb 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Kallikreins*
Kinins*
Blood Coagulation ; Factor XII ; Humans ; Kallikrein-Kinin System
Czasopismo naukowe
Tytuł :
The role of kinins in the proliferation of fibroblast primed with TNF in scratch wound assay: Kinins and cell proliferation.
Autorzy :
França AJVBDV; Postgraduate Program in Pharmaceutical Science, Universidade do Vale do Itajaí, Itajaí, Santa Catarina, Brazil; Cosmethology Course, Universidade do Vale do Itajaí, Itajaí, Santa Catarina, Brazil.
De Faveri R; Biomedicine Course, Universidade do Vale do Itajaí, Itajaí, Santa Catarina, Brazil.
Nunes R; Postgraduate Program in Pharmaceutical Science, Universidade do Vale do Itajaí, Itajaí, Santa Catarina, Brazil.
Steimbach VMB; Postgraduate Program in Pharmaceutical Science, Universidade do Vale do Itajaí, Itajaí, Santa Catarina, Brazil.
Santin JR; Postgraduate Program in Pharmaceutical Science, Universidade do Vale do Itajaí, Itajaí, Santa Catarina, Brazil.
Quintão NLM; Postgraduate Program in Pharmaceutical Science, Universidade do Vale do Itajaí, Itajaí, Santa Catarina, Brazil. Electronic address: .
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Źródło :
International immunopharmacology [Int Immunopharmacol] 2018 Dec; Vol. 65, pp. 23-28. Date of Electronic Publication: 2018 Sep 27.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Movement/*drug effects
Cell Movement/*physiology
Cell Proliferation/*drug effects
Fibroblasts/*metabolism
Kinins/*metabolism
Tumor Necrosis Factor-alpha/*pharmacology
Animals ; Cell Line ; Gene Expression Regulation/drug effects ; Kinins/genetics ; Mice
Czasopismo naukowe
Tytuł :
Synthesis, aphicidal activity and conformation of novel insect kinin analogues as potential eco-friendly insecticides.
Autorzy :
Zhang C; Department of Applied Chemistry, College of Science, China Agricultural University, Beijing, P. R. China.
Li X; Department of Applied Chemistry, College of Science, China Agricultural University, Beijing, P. R. China.
Song D; Department of Entomology, College of Plant Protection, China Agricultural University, Beijing, P. R. China.
Ling Y; Department of Applied Chemistry, College of Science, China Agricultural University, Beijing, P. R. China.
Zhou Y; Department of Applied Chemistry, College of Science, China Agricultural University, Beijing, P. R. China.
Yang X; Department of Applied Chemistry, College of Science, China Agricultural University, Beijing, P. R. China.
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Źródło :
Pest management science [Pest Manag Sci] 2020 Oct; Vol. 76 (10), pp. 3432-3439. Date of Electronic Publication: 2020 Jan 06.
Typ publikacji :
Journal Article
MeSH Terms :
Aphids*
Animals ; Insecta ; Insecticides ; Kinins ; Molecular Conformation
Czasopismo naukowe
Tytuł :
Activity of native tick kinins and peptidomimetics on the cognate target G protein-coupled receptor from the cattle fever tick, Rhipicephalus microplus (Acari: Ixodidae).
Autorzy :
Xiong C; Department of Entomology, Texas A&M University, College Station, TX, USA.
Kaczmarek K; Institute of Organic Chemistry, Lodz University of Technology, Lodz, Poland.; Insect Neuropeptide Lab, Insect Control and Cotton Disease Research Unit, Southern Plains Agricultural Research Center, U.S. Department of Agriculture, College Station, TX, USA.
Zabrocki J; Institute of Organic Chemistry, Lodz University of Technology, Lodz, Poland.; Insect Neuropeptide Lab, Insect Control and Cotton Disease Research Unit, Southern Plains Agricultural Research Center, U.S. Department of Agriculture, College Station, TX, USA.
Nachman RJ; Insect Neuropeptide Lab, Insect Control and Cotton Disease Research Unit, Southern Plains Agricultural Research Center, U.S. Department of Agriculture, College Station, TX, USA.
Pietrantonio PV; Department of Entomology, Texas A&M University, College Station, TX, USA.
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Źródło :
Pest management science [Pest Manag Sci] 2020 Oct; Vol. 76 (10), pp. 3423-3431. Date of Electronic Publication: 2020 Jan 08.
Typ publikacji :
Journal Article
MeSH Terms :
Rhipicephalus*
Animals ; Cattle ; Female ; Kinins ; Neuropeptides ; Peptidomimetics
Czasopismo naukowe
Tytuł :
The effects of anti-VEGF and kinin B 1 receptor blockade on retinal inflammation in laser-induced choroidal neovascularization.
Autorzy :
Hachana S; School of Optometry, Université de Montréal, Montréal, Quebec, Canada.; Department of Pharmacology and Physiology, Université de Montréal, Montréal, Quebec, Canada.
Fontaine O; School of Optometry, Université de Montréal, Montréal, Quebec, Canada.; Department of Ophthalmology, Maisonneuve-Rosemont Hospital Research Centre, Montréal, Quebec, Canada.
Sapieha P; Department of Ophthalmology, Maisonneuve-Rosemont Hospital Research Centre, Montréal, Quebec, Canada.
Lesk M; Department of Ophthalmology, Maisonneuve-Rosemont Hospital Research Centre, Montréal, Quebec, Canada.
Couture R; Department of Pharmacology and Physiology, Université de Montréal, Montréal, Quebec, Canada.
Vaucher E; School of Optometry, Université de Montréal, Montréal, Quebec, Canada.
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Źródło :
British journal of pharmacology [Br J Pharmacol] 2020 May; Vol. 177 (9), pp. 1949-1966. Date of Electronic Publication: 2020 Feb 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Choroidal Neovascularization*/drug therapy
Neurodegenerative Diseases*
Animals ; Disease Models, Animal ; Endothelial Cells ; Inflammation/drug therapy ; Kinins ; Lasers ; RNA, Messenger ; Rats ; Rats, Long-Evans ; Retina
Czasopismo naukowe

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