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    Wyświetlanie 1-8 z 8
    Tytuł:
    Enhanced and complementary benefits of a nalfurafine and fingolimod combination to treat immune-driven demyelination.
    Autorzy:
    Robichon K; School of Biological Sciences Victoria University of Wellington Wellington New Zealand.; Centre for Biodiscovery Wellington Victoria University of Wellington Wellington New Zealand.
    Bibi R; School of Biological Sciences Victoria University of Wellington Wellington New Zealand.; Centre for Biodiscovery Wellington Victoria University of Wellington Wellington New Zealand.
    Kiernan M; School of Biological Sciences Victoria University of Wellington Wellington New Zealand.; Centre for Biodiscovery Wellington Victoria University of Wellington Wellington New Zealand.
    Denny L; School of Biological Sciences Victoria University of Wellington Wellington New Zealand.; Centre for Biodiscovery Wellington Victoria University of Wellington Wellington New Zealand.
    Prisinzano TE; Department of Medicinal Chemistry University of Kentucky Lawrence KY USA.
    Kivell BM; School of Biological Sciences Victoria University of Wellington Wellington New Zealand.; Centre for Biodiscovery Wellington Victoria University of Wellington Wellington New Zealand.
    La Flamme AC; School of Biological Sciences Victoria University of Wellington Wellington New Zealand.; Centre for Biodiscovery Wellington Victoria University of Wellington Wellington New Zealand.; Malaghan Institute of Medical Research Wellington New Zealand.
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    Źródło:
    Clinical & translational immunology [Clin Transl Immunology] 2023 Dec 12; Vol. 12 (12), pp. e1480. Date of Electronic Publication: 2023 Dec 12 (Print Publication: 2023).
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors.
    Autorzy:
    van de Wetering R; School of Biological Sciences, Centre for Biodiscovery, Victoria University of Wellington, Wellington 6012, New Zealand.
    Ewald A; School of Biological Sciences, Centre for Biodiscovery, Victoria University of Wellington, Wellington 6012, New Zealand.
    Welsh S; School of Biological Sciences, Centre for Biodiscovery, Victoria University of Wellington, Wellington 6012, New Zealand.
    Kornberger L; Department of Pharmaceutical Sciences, University of Kentucky, Lexington, KY 40506, USA.
    Williamson SE; Department of Medicinal Chemistry, University of Kansas, Lawrence, KS 66045, USA.
    McElroy BD; Laboratory on the Biology of Addictive Diseases, The Rockefeller University, New York, NY 10065, USA.
    Butelman ER; Laboratory on the Biology of Addictive Diseases, The Rockefeller University, New York, NY 10065, USA.
    Prisinzano TE; Department of Pharmaceutical Sciences, University of Kentucky, Lexington, KY 40506, USA.; Department of Medicinal Chemistry, University of Kansas, Lawrence, KS 66045, USA.
    Kivell BM; School of Biological Sciences, Centre for Biodiscovery, Victoria University of Wellington, Wellington 6012, New Zealand.
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    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2023 Jun 19; Vol. 28 (12). Date of Electronic Publication: 2023 Jun 19.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Cocaine*/pharmacology
    Mice ; Rats ; Humans ; Animals ; Receptors, Opioid, kappa/metabolism ; Rats, Sprague-Dawley ; HEK293 Cells ; Anxiety/drug therapy ; Reward ; Locomotion
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Sex Differences in the Behavioural Aspects of the Cuprizone-Induced Demyelination Model in Mice.
    Autorzy:
    Paton KF; Centre for Biodiscovery, School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand.
    Hong S; Centre for Biodiscovery, School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand.
    Biggerstaff A; Centre for Biodiscovery, School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand.
    Kivell BM; Centre for Biodiscovery, School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand.
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    Źródło:
    Brain sciences [Brain Sci] 2022 Dec 08; Vol. 12 (12). Date of Electronic Publication: 2022 Dec 08.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Nalfurafine reduces neuroinflammation and drives remyelination in models of CNS demyelinating disease.
    Autorzy:
    Denny L; School of Biological Sciences Victoria University of Wellington Wellington New Zealand.; Centre for Biodiscovery Victoria University of Wellington Wellington New Zealand.
    Al Abadey A; School of Biological Sciences Victoria University of Wellington Wellington New Zealand.; Centre for Biodiscovery Victoria University of Wellington Wellington New Zealand.
    Robichon K; School of Biological Sciences Victoria University of Wellington Wellington New Zealand.; Centre for Biodiscovery Victoria University of Wellington Wellington New Zealand.
    Templeton N; School of Biological Sciences Victoria University of Wellington Wellington New Zealand.; Centre for Biodiscovery Victoria University of Wellington Wellington New Zealand.
    Prisinzano TE; Department of Pharmaceutical Sciences University of Kentucky Lexington KY 40536 USA.
    Kivell BM; School of Biological Sciences Victoria University of Wellington Wellington New Zealand.; Centre for Biodiscovery Victoria University of Wellington Wellington New Zealand.
    La Flamme AC; School of Biological Sciences Victoria University of Wellington Wellington New Zealand.; Centre for Biodiscovery Victoria University of Wellington Wellington New Zealand.; Malaghan Institute of Medical Research Wellington New Zealand.
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    Źródło:
    Clinical & translational immunology [Clin Transl Immunology] 2021 Jan 17; Vol. 10 (1), pp. e1234. Date of Electronic Publication: 2021 Jan 17 (Print Publication: 2021).
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Kappa Opioid Receptor Agonist Mesyl Sal B Attenuates Behavioral Sensitization to Cocaine with Fewer Aversive Side-Effects than Salvinorin A in Rodents.
    Autorzy:
    Kivell BM; School of Biological Science, Centre for Biodiscovery, Victoria University of Wellington, P.O. Box 600, Wellington, New Zealand. bronwyn.kivell@vuw.ac.nz.
    Paton KF; School of Biological Science, Centre for Biodiscovery, Victoria University of Wellington, P.O. Box 600, Wellington, New Zealand. .
    Kumar N; School of Biological Science, Centre for Biodiscovery, Victoria University of Wellington, P.O. Box 600, Wellington, New Zealand. .
    Morani AS; School of Biological Science, Centre for Biodiscovery, Victoria University of Wellington, P.O. Box 600, Wellington, New Zealand. .
    Culverhouse A; School of Biological Science, Centre for Biodiscovery, Victoria University of Wellington, P.O. Box 600, Wellington, New Zealand. .
    Shepherd A; School of Biological Science, Centre for Biodiscovery, Victoria University of Wellington, P.O. Box 600, Wellington, New Zealand. .
    Welsh SA; School of Biological Science, Centre for Biodiscovery, Victoria University of Wellington, P.O. Box 600, Wellington, New Zealand. .
    Biggerstaff A; School of Biological Science, Centre for Biodiscovery, Victoria University of Wellington, P.O. Box 600, Wellington, New Zealand. .
    Crowley RS; Department of Medicinal Chemistry, University of Kansas, Lawrence, KS 6604, USA. .
    Prisinzano TE; Department of Medicinal Chemistry, University of Kansas, Lawrence, KS 6604, USA. .
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    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2018 Oct 11; Vol. 23 (10). Date of Electronic Publication: 2018 Oct 11.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Behavior, Animal/*drug effects
    Cocaine/*adverse effects
    Cocaine-Related Disorders/*metabolism
    Cocaine-Related Disorders/*psychology
    Diterpenes/*pharmacology
    Diterpenes, Clerodane/*pharmacology
    Mesylates/*pharmacology
    Receptors, Opioid, kappa/*agonists
    Animals ; Anxiety/drug therapy ; Anxiety/metabolism ; Cocaine-Related Disorders/drug therapy ; Diterpenes/adverse effects ; Diterpenes/chemistry ; Diterpenes, Clerodane/adverse effects ; Diterpenes, Clerodane/chemistry ; Learning/drug effects ; Male ; Mesylates/adverse effects ; Mesylates/chemistry ; Mice ; Motor Activity/drug effects ; Nociception/drug effects ; Pain/drug therapy ; Pain/etiology ; Pain/metabolism ; Rats ; Recognition, Psychology/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The C-2 derivatives of salvinorin A, ethoxymethyl ether Sal B and β-tetrahydropyran Sal B, have anti-cocaine properties with minimal side effects.
    Autorzy:
    Ewald AWM; School of Biological Sciences, Centre for Biodiscovery, Victoria University of Wellington, Wellington, New Zealand.
    Bosch PJ; School of Biological Sciences, Centre for Biodiscovery, Victoria University of Wellington, Wellington, New Zealand.; Department of Biology, University of Iowa, Iowa City, IA, 52242, USA.
    Culverhouse A; School of Biological Sciences, Centre for Biodiscovery, Victoria University of Wellington, Wellington, New Zealand.
    Crowley RS; Department of Medicinal Chemistry, School of Pharmacy, University of Kansas, Lawrence, KS, USA.
    Neuenswander B; Department of Medicinal Chemistry, School of Pharmacy, University of Kansas, Lawrence, KS, USA.
    Prisinzano TE; Department of Medicinal Chemistry, School of Pharmacy, University of Kansas, Lawrence, KS, USA.
    Kivell BM; School of Biological Sciences, Centre for Biodiscovery, Victoria University of Wellington, Wellington, New Zealand. Bronwyn.kivell@vuw.ac.nz.
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    Źródło:
    Psychopharmacology [Psychopharmacology (Berl)] 2017 Aug; Vol. 234 (16), pp. 2499-2514. Date of Electronic Publication: 2017 May 23.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Avoidance Learning/*drug effects
    Cocaine/*pharmacology
    Diterpenes, Clerodane/*pharmacology
    Drug-Seeking Behavior/*drug effects
    Motor Activity/*drug effects
    Animals ; Anxiety/drug therapy ; Cocaine-Related Disorders/drug therapy ; Diterpenes, Clerodane/therapeutic use ; Male ; Rats ; Rats, Sprague-Dawley ; Self Administration ; Swimming
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Proteomics Analysis of Dorsal Striatum Reveals Changes in Synaptosomal Proteins following Methamphetamine Self-Administration in Rats.
    Autorzy:
    Bosch PJ; Centre for Biodiscovery, School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand.
    Peng L; Centre for Biodiscovery, School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand.
    Kivell BM; Centre for Biodiscovery, School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand.
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    Źródło:
    PloS one [PLoS One] 2015 Oct 20; Vol. 10 (10), pp. e0139829. Date of Electronic Publication: 2015 Oct 20 (Print Publication: 2015).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Central Nervous System Stimulants/*administration & dosage
    Corpus Striatum/*metabolism
    Methamphetamine/*administration & dosage
    Synaptosomes/*metabolism
    Animals ; Corpus Striatum/drug effects ; Male ; Proteomics ; Rats ; Rats, Sprague-Dawley ; Self Administration ; Synaptosomes/drug effects ; Tandem Mass Spectrometry
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    mRNA and microRNA analysis reveals modulation of biochemical pathways related to addiction in the ventral tegmental area of methamphetamine self-administering rats.
    Autorzy:
    Bosch PJ; Centre for Biodiscovery, School of Biological Sciences, Victoria University of Wellington, Kelburn Parade, PO Box 600, Wellington, 6140, New Zealand. .
    Benton MC; Institute of Environmental Science and Research, Wellington, New Zealand. .; Genomics Research Centre, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia. .
    Macartney-Coxson D; Institute of Environmental Science and Research, Wellington, New Zealand. .
    Kivell BM; Centre for Biodiscovery, School of Biological Sciences, Victoria University of Wellington, Kelburn Parade, PO Box 600, Wellington, 6140, New Zealand. Bronwyn.kivell@vuw.ac.nz.
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    Źródło:
    BMC neuroscience [BMC Neurosci] 2015 Jul 19; Vol. 16, pp. 43. Date of Electronic Publication: 2015 Jul 19.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Central Nervous System Stimulants/*administration & dosage
    Methamphetamine/*administration & dosage
    MicroRNAs/*metabolism
    RNA, Messenger/*metabolism
    Ventral Tegmental Area/*drug effects
    Ventral Tegmental Area/*metabolism
    Amphetamine-Related Disorders/metabolism ; Animals ; Catheters, Indwelling ; Drug-Seeking Behavior/physiology ; Male ; Microarray Analysis ; Random Allocation ; Rats, Sprague-Dawley ; Real-Time Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction ; Self Administration
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-8 z 8

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