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Wyszukujesz frazę ""Klein, Jon B."" wg kryterium: Autor


Wyświetlanie 1-12 z 12
Tytuł :
The role of charge in the toxicity of polymer-coated cerium oxide nanomaterials to Caenorhabditis elegans.
Autorzy :
Arndt DA; Department of Plant and Soil Sciences, University of Kentucky, Lexington, KY, United States.
Oostveen EK; Department of Plant and Soil Sciences, University of Kentucky, Lexington, KY, United States.
Triplett J; Department of Chemistry, University of Kentucky, Lexington, KY, United States.
Butterfield DA; Department of Chemistry, University of Kentucky, Lexington, KY, United States.
Tsyusko OV; Department of Plant and Soil Sciences, University of Kentucky, Lexington, KY, United States.
Collin B; CNRS, IRD, Coll. France, CEREGE, Aix Marseille Université, Aix-en-Provence, France.
Starnes DL; Department of Plant and Soil Sciences, University of Kentucky, Lexington, KY, United States.
Cai J; Center for Proteomics, University of Louisville, Louisville, KY, United States.
Klein JB; Center for Proteomics, University of Louisville, Louisville, KY, United States.
Nass R; Department of Pharmacology and Toxicology, Indiana University, Indianapolis, IN, United States.
Unrine JM; Department of Plant and Soil Sciences, University of Kentucky, Lexington, KY, United States. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP [Comp Biochem Physiol C Toxicol Pharmacol] 2017 Oct; Vol. 201, pp. 1-10. Date of Electronic Publication: 2017 Sep 06.
Typ publikacji :
Journal Article
MeSH Terms :
Cerium/*toxicity
Nanostructures/*toxicity
Polymers/*chemistry
Animals ; Caenorhabditis elegans ; Caenorhabditis elegans Proteins/genetics ; Caenorhabditis elegans Proteins/metabolism ; Cerium/chemistry ; Gene Expression Regulation/drug effects ; Intestinal Mucosa/metabolism ; Intestines/drug effects ; Metal Nanoparticles/toxicity ; Nanostructures/chemistry ; Surface Properties
Czasopismo naukowe
Tytuł :
Comparative proteomic analyses of the parietal lobe from rhesus monkeys fed a high-fat/sugar diet with and without resveratrol supplementation, relative to a healthy diet: Insights into the roles of unhealthy diets and resveratrol on function.
Autorzy :
Swomley AM; Department of Chemistry, University of Kentucky, Lexington, KY 40536, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA.
Triplett JC; Department of Chemistry, University of Kentucky, Lexington, KY 40536, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA.
Keeney JT; Department of Chemistry, University of Kentucky, Lexington, KY 40536, USA.
Warrier G; Department of Chemistry, University of Kentucky, Lexington, KY 40536, USA.
Pearson KJ; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA; Molecular and Biomedical Pharmacology and Nutrition, University of Kentucky, Lexington, KY 40536, USA.
Mattison JA; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
de Cabo R; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
Cai J; Proteomics Center, University of Louisville, Louisville, KY 40202, USA.
Klein JB; Proteomics Center, University of Louisville, Louisville, KY 40202, USA.
Butterfield DA; Department of Chemistry, University of Kentucky, Lexington, KY 40536, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA. Electronic address: .
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Źródło :
The Journal of nutritional biochemistry [J Nutr Biochem] 2017 Jan; Vol. 39, pp. 169-179. Date of Electronic Publication: 2016 Oct 13.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Diet, High-Fat/*adverse effects
Dietary Sugars/*adverse effects
Parietal Lobe/*metabolism
Proteome/*metabolism
Stilbenes/*pharmacology
2',3'-Cyclic Nucleotide 3'-Phosphodiesterase/genetics ; 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase/metabolism ; Animals ; Brain/drug effects ; Brain/metabolism ; Diet, Healthy ; Dietary Sugars/administration & dosage ; Dietary Supplements ; Disease Models, Animal ; Glutamate-Ammonia Ligase/genetics ; Glutamate-Ammonia Ligase/metabolism ; Macaca mulatta ; Male ; Reproducibility of Results ; Resveratrol ; Signal Transduction
Czasopismo naukowe
Tytuł :
An investigation of the molecular mechanisms engaged before and after the development of Alzheimer disease neuropathology in Down syndrome: a proteomics approach.
Autorzy :
Cenini G; Department of Chemistry, Center of Membrane Sciences, and Sanders-Brown Center on Aging, and.
Fiorini A; Department of Chemistry, Center of Membrane Sciences, and Sanders-Brown Center on Aging, and; Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy.
Sultana R; Department of Chemistry, Center of Membrane Sciences, and Sanders-Brown Center on Aging, and.
Perluigi M; Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy.
Cai J; Division of Nephrology, Department of Medicine and Proteomics Center, University of Louisville, Louisville, KY 40292, USA.
Klein JB; Division of Nephrology, Department of Medicine and Proteomics Center, University of Louisville, Louisville, KY 40292, USA.
Head E; Department of Molecular and Biomedical Pharmacology and Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA.
Butterfield DA; Department of Chemistry, Center of Membrane Sciences, and Sanders-Brown Center on Aging, and. Electronic address: .
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2014 Nov; Vol. 76, pp. 89-95. Date of Electronic Publication: 2014 Aug 20.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Alzheimer Disease/*metabolism
Biomarkers/*metabolism
Down Syndrome/*metabolism
Proteome/*analysis
Proteomics/*methods
Adolescent ; Alzheimer Disease/etiology ; Alzheimer Disease/pathology ; Case-Control Studies ; Child ; Chromatography, Liquid ; Down Syndrome/complications ; Down Syndrome/pathology ; Electrophoresis, Gel, Two-Dimensional ; Female ; Humans ; Male ; Middle Aged ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Czasopismo naukowe
Tytuł :
Dietary vitamin D deficiency in rats from middle to old age leads to elevated tyrosine nitration and proteomics changes in levels of key proteins in brain: implications for low vitamin D-dependent age-related cognitive decline.
Autorzy :
Keeney JTR; Department of Chemistry, Center of Membrane Sciences, Sanders Brown Center on Aging, University of Kentucky, Lexington, KY 40506, USA.
Förster S; Department of Chemistry, Center of Membrane Sciences, Sanders Brown Center on Aging, University of Kentucky, Lexington, KY 40506, USA.
Sultana R; Department of Chemistry, Center of Membrane Sciences, Sanders Brown Center on Aging, University of Kentucky, Lexington, KY 40506, USA.
Brewer LD; Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, Lexington, KY 40536, USA.
Latimer CS; Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, Lexington, KY 40536, USA.
Cai J; Division of Nephrology, Department of Medicine and Proteomics Center, University of Louisville, Louisville, KY 40292, USA.
Klein JB; Division of Nephrology, Department of Medicine and Proteomics Center, University of Louisville, Louisville, KY 40292, USA.
Porter NM; Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, Lexington, KY 40536, USA.
Butterfield DA; Department of Chemistry, Center of Membrane Sciences, Sanders Brown Center on Aging, University of Kentucky, Lexington, KY 40506, USA. Electronic address: .
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2013 Dec; Vol. 65, pp. 324-334. Date of Electronic Publication: 2013 Jul 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Brain/*metabolism
Cognition Disorders/*etiology
Tyrosine/*metabolism
Vitamin D Deficiency/*complications
Vitamin D Deficiency/*metabolism
Aging/metabolism ; Animals ; Blotting, Western ; Cognition Disorders/metabolism ; Diet ; Disease Models, Animal ; Isoelectric Focusing ; Male ; Mass Spectrometry ; Nitrosation ; Proteomics ; Rats ; Rats, Inbred F344 ; Tyrosine/analogs & derivatives
Czasopismo naukowe
Tytuł :
Antisense directed against PS-1 gene decreases brain oxidative markers in aged senescence accelerated mice (SAMP8) and reverses learning and memory impairment: a proteomics study.
Autorzy :
Fiorini A; Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy; Department of Chemistry, Center of Membrane Sciences, Sanders Brown Center on Aging, University of Kentucky, Lexington, KY 40506, USA.
Sultana R; Department of Chemistry, Center of Membrane Sciences, Sanders Brown Center on Aging, University of Kentucky, Lexington, KY 40506, USA.
Förster S; Department of Chemistry, Center of Membrane Sciences, Sanders Brown Center on Aging, University of Kentucky, Lexington, KY 40506, USA; Department of Biochemistry, Institute of Animal Sciences, University of Bonn, Bonn, Germany.
Perluigi M; Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy.
Cenini G; Department of Chemistry, Center of Membrane Sciences, Sanders Brown Center on Aging, University of Kentucky, Lexington, KY 40506, USA.
Cini C; Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy.
Cai J; Department of Nephrology and Proteomics Center, University of Louisville, Louisville, KY 40292, USA.
Klein JB; Department of Nephrology and Proteomics Center, University of Louisville, Louisville, KY 40292, USA.
Farr SA; Division of Geriatric Medicine Saint Louis University School of Medicine, St. Louis, MO, USA; VA Medical Center, St. Louis, MO, USA.
Niehoff ML; Division of Geriatric Medicine Saint Louis University School of Medicine, St. Louis, MO, USA; VA Medical Center, St. Louis, MO, USA.
Morley JE; Division of Geriatric Medicine Saint Louis University School of Medicine, St. Louis, MO, USA; VA Medical Center, St. Louis, MO, USA.
Kumar VB; Division of Geriatric Medicine Saint Louis University School of Medicine, St. Louis, MO, USA; VA Medical Center, St. Louis, MO, USA.
Butterfield DA; Department of Chemistry, Center of Membrane Sciences, Sanders Brown Center on Aging, University of Kentucky, Lexington, KY 40506, USA. Electronic address: .
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2013 Dec; Vol. 65, pp. 1-14. Date of Electronic Publication: 2013 Jun 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Hippocampus/*drug effects
Maze Learning/*drug effects
Oligonucleotides, Antisense/*pharmacology
Oxidative Stress/*drug effects
Presenilin-1/*antagonists & inhibitors
Alzheimer Disease/metabolism ; Animals ; Blotting, Western ; Disease Models, Animal ; Electrophoresis, Gel, Two-Dimensional ; Hippocampus/metabolism ; Immunoprecipitation ; Mass Spectrometry ; Mice ; Proteomics
Czasopismo naukowe
Tytuł :
Lymphocyte mitochondria: toward identification of peripheral biomarkers in the progression of Alzheimer disease.
Autorzy :
Sultana R; Department of Chemistry, Center of Membrane Sciences, Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40506-0055, USA.
Baglioni M; Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.
Cecchetti R; Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.
Cai J; Department of Nephrology and Proteomics Center, University of Louisville, Louisville, KY 40292, USA.
Klein JB; Department of Nephrology and Proteomics Center, University of Louisville, Louisville, KY 40292, USA.
Bastiani P; Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.
Ruggiero C; Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.
Mecocci P; Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy. Electronic address: .
Butterfield DA; Department of Chemistry, Center of Membrane Sciences, Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40506-0055, USA. Electronic address: .
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2013 Dec; Vol. 65, pp. 595-606. Date of Electronic Publication: 2013 Aug 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Alzheimer Disease/*diagnosis
Biomarkers/*analysis
Cognitive Dysfunction/*diagnosis
Lymphocytes/*metabolism
Mitochondria/*metabolism
Aged ; Aged, 80 and over ; Alzheimer Disease/metabolism ; Cognitive Dysfunction/metabolism ; Disease Progression ; Electrophoresis, Gel, Two-Dimensional ; Female ; Humans ; Isoelectric Focusing ; Male ; Mass Spectrometry ; Oxidative Stress/physiology ; Proteomics
Czasopismo naukowe
Tytuł :
Redox proteomic identification of oxidized cardiac proteins in adriamycin-treated mice.
Autorzy :
Chen Y; Graduate Center for Toxicology, University of Kentucky, Lexington, KY 40506, USA.
Daosukho C
Opii WO
Turner DM
Pierce WM
Klein JB
Vore M
Butterfield DA
St Clair DK
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2006 Nov 01; Vol. 41 (9), pp. 1470-7. Date of Electronic Publication: 2006 Aug 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Oxidative Stress*
Proteomics*
Antibiotics, Antineoplastic/*pharmacology
Doxorubicin/*pharmacology
Heart/*physiology
Proteins/*metabolism
Animals ; Blotting, Western ; Electrophoresis, Gel, Two-Dimensional ; Heart/drug effects ; Hydrogen Peroxide/pharmacology ; Male ; Mass Spectrometry ; Mice ; Mice, Inbred C57BL ; Oxidants/pharmacology ; Oxidation-Reduction ; Proteins/chemistry
Czasopismo naukowe
Tytuł :
Urinary protein expression patterns in children with sleep-disordered breathing: preliminary findings.
Autorzy :
Krishna J; Division of Pediatric Sleep Medicine and Kosair Children's Hospital Research Institute, Department of Pediatrics, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Shah ZA
Merchant M
Klein JB
Gozal D
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Źródło :
Sleep medicine [Sleep Med] 2006 Apr; Vol. 7 (3), pp. 221-7. Date of Electronic Publication: 2006 Mar 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gelsolin/*genetics
Gelsolin/*urine
Heparan Sulfate Proteoglycans/*genetics
Heparan Sulfate Proteoglycans/*urine
Proteomics/*methods
Sleep Apnea Syndromes/*genetics
Sleep Apnea Syndromes/*urine
Body Mass Index ; Child ; Child, Preschool ; Female ; Humans ; Male ; Oximetry ; Polysomnography ; Sleep Apnea Syndromes/diagnosis ; Sleep Apnea, Obstructive/diagnosis ; Sleep Apnea, Obstructive/genetics ; Sleep Apnea, Obstructive/urine ; Sleep, REM/physiology ; Snoring/epidemiology
Czasopismo naukowe
Tytuł :
Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis.
Autorzy :
Poon HF; Department of Chemistry, University of Kentucky, Lexington KY 40506, USA.
Hensley K
Thongboonkerd V
Merchant ML
Lynn BC
Pierce WM
Klein JB
Calabrese V
Butterfield DA
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2005 Aug 15; Vol. 39 (4), pp. 453-62. Date of Electronic Publication: 2005 Apr 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Proteomics*
Amyotrophic Lateral Sclerosis/*metabolism
Superoxide Dismutase/*genetics
Animals ; Biomarkers, Tumor/metabolism ; Blotting, Western ; Disease Models, Animal ; Electrophoresis, Gel, Two-Dimensional ; Mice ; Mice, Transgenic ; Nerve Tissue Proteins/metabolism ; Oxidation-Reduction ; Point Mutation ; Spinal Cord/metabolism ; Ubiquitin Thiolesterase/metabolism
Czasopismo naukowe
Tytuł :
Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis.
Autorzy :
Perluigi M; Department of Biochemical Sciences, University of Rome La Sapienza, Rome 00185, Italy.
Fai Poon H
Hensley K
Pierce WM
Klein JB
Calabrese V
De Marco C
Butterfield DA
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2005 Apr 01; Vol. 38 (7), pp. 960-8.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Aldehydes/*analysis
Amyotrophic Lateral Sclerosis/*metabolism
HSP70 Heat-Shock Proteins/*analysis
Nerve Tissue Proteins/*analysis
Phosphopyruvate Hydratase/*analysis
Spinal Cord/*chemistry
Amyotrophic Lateral Sclerosis/genetics ; Animals ; Disease Models, Animal ; HSP70 Heat-Shock Proteins/metabolism ; Intercellular Signaling Peptides and Proteins ; Lipid Peroxidation ; Mice ; Mice, Transgenic ; Nerve Tissue Proteins/metabolism ; Oxidative Stress ; Phosphopyruvate Hydratase/metabolism ; Proteomics ; Spinal Cord/metabolism ; Superoxide Dismutase/genetics
Czasopismo naukowe
Tytuł :
Proteomic identification of a novel protein regulated in CA1 and CA3 hippocampal regions during intermittent hypoxia.
Autorzy :
Klein JB; Department of Medicine, Core Proteomics Laboratory, Kidney Disease Program, University of Louisville, 570 South Preston Street, Suite 102, Louisville, KY 40202, USA. jon.klein@louisville.edu
Gozal D
Pierce WM
Thongboonkerd V
Scherzer JA
Sachleben LR
Guo SZ
Cai J
Gozal E
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Źródło :
Respiratory physiology & neurobiology [Respir Physiol Neurobiol] 2003 Jul 16; Vol. 136 (2-3), pp. 91-103.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Brain Chemistry*
Hippocampus/*metabolism
Hypoxia/*metabolism
Nerve Tissue Proteins/*isolation & purification
Proteomics/*methods
Animals ; Binding Sites ; Blotting, Western ; Computational Biology/methods ; Databases, Protein ; Electrophoresis, Gel, Two-Dimensional ; Hippocampus/anatomy & histology ; Male ; Mass Spectrometry/methods ; Nerve Tissue Proteins/metabolism ; Protein Kinase C/metabolism ; Protein Structure, Tertiary ; Rats ; Rats, Sprague-Dawley ; Receptors, Immunologic/metabolism ; Receptors, Scavenger ; Sequence Analysis, Protein/methods ; Time Factors
Czasopismo naukowe
Tytuł :
Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1.
Autorzy :
Castegna A; Department of Chemistry, Center of Membrane Sciences, University of Kentucky, Lexington 40506-0055, USA.
Aksenov M
Aksenova M
Thongboonkerd V
Klein JB
Pierce WM
Booze R
Markesbery WR
Butterfield DA
Pokaż więcej
Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2002 Aug 15; Vol. 33 (4), pp. 562-71.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Brain Chemistry*
Proteomics*
Alzheimer Disease/*metabolism
Creatine Kinase/*chemistry
Glutamate-Ammonia Ligase/*chemistry
Isoenzymes/*chemistry
Nerve Tissue Proteins/*chemistry
Thiolester Hydrolases/*chemistry
Amyloid beta-Protein Precursor/metabolism ; Antibodies, Monoclonal/immunology ; Blotting, Western ; Creatine Kinase/physiology ; Creatine Kinase, BB Form ; Electrophoresis, Gel, Two-Dimensional ; Free Radicals ; Glutamate-Ammonia Ligase/immunology ; Glutamate-Ammonia Ligase/physiology ; Glutamic Acid/metabolism ; Glutamine/metabolism ; Humans ; Image Processing, Computer-Assisted ; Isoenzymes/physiology ; Nerve Degeneration ; Nerve Tissue Proteins/physiology ; Oxidation-Reduction ; Rosaniline Dyes ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ; Staining and Labeling ; Thiolester Hydrolases/physiology ; Ubiquitin Thiolesterase
Czasopismo naukowe
    Wyświetlanie 1-12 z 12

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