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Wyszukujesz frazę ""Klein, Jon B."" wg kryterium: Autor


Tytuł :
Protein Mass Spectrometry Made Simple.
Autorzy :
Klein JB; University of Louisville School of Medicine and Robley Rex Veterans Administration Medical Center, Louisville, Kentucky; and jon.klein@louisville.edu.
A Knepper M; Epithelial Systems Biology Laboratory, Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland.
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Źródło :
Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2018 Jun; Vol. 29 (6), pp. 1585-1587. Date of Electronic Publication: 2018 May 03.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Autoantigens*
Proteins*
Mass Spectrometry
Czasopismo naukowe
Tytuł :
Oncostatin M receptor β and cysteine/histidine-rich 1 are biomarkers of the response to erythropoietin in hemodialysis patients.
Autorzy :
Merchant ML; Department of Medicine, University of Louisville, Louisville, Kentucky, USA.
Gaweda AE; Department of Medicine, University of Louisville, Louisville, Kentucky, USA.
Dailey AJ; Department of Medicine, University of Louisville, Louisville, Kentucky, USA.; The Robley Rex Veterans Affairs Medical Center, Louisville, Kentucky, USA.
Wilkey DW; Department of Medicine, University of Louisville, Louisville, Kentucky, USA.
Zhang X; Department of Medicine, Ohio State University School of Medicine, Columbus, Ohio, USA.
Rovin BH; Department of Medicine, Ohio State University School of Medicine, Columbus, Ohio, USA.
Klein JB; Department of Medicine, University of Louisville, Louisville, Kentucky, USA.; The Robley Rex Veterans Affairs Medical Center, Louisville, Kentucky, USA.
Brier ME; Department of Medicine, University of Louisville, Louisville, Kentucky, USA.; The Robley Rex Veterans Affairs Medical Center, Louisville, Kentucky, USA.
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Źródło :
Kidney international [Kidney Int] 2011 Mar; Vol. 79 (5), pp. 546-554. Date of Electronic Publication: 2010 Dec 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Renal Dialysis*
Erythropoietin/*therapeutic use
Oncostatin M Receptor beta Subunit/*blood
Proteins/*analysis
Biomarkers/blood ; Cytokines/blood ; Female ; Fibrinopeptide B/analysis ; Humans ; Male ; Peptide Fragments/blood ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Czasopismo naukowe
Tytuł :
Proteomic discovery of diabetic nephropathy biomarkers.
Autorzy :
Merchant ML; Renal Division, University of Louisville, Louisville, KY 40202, USA. />Klein JB
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Źródło :
Advances in chronic kidney disease [Adv Chronic Kidney Dis] 2010 Nov; Vol. 17 (6), pp. 480-6.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Diabetic Nephropathies/*diagnosis
Peptides/*analysis
Proteins/*analysis
Proteomics/*methods
Renal Insufficiency/*diagnosis
Age Factors ; Biomarkers/analysis ; Diabetes Mellitus, Type 1/metabolism ; Diabetes Mellitus, Type 2/metabolism ; Diabetic Nephropathies/physiopathology ; Disease Progression ; Early Diagnosis ; Humans ; Proteinuria
Czasopismo naukowe
Tytuł :
Proteomic techniques identify urine proteins that differentiate patients with interstitial cystitis from asymptomatic control subjects.
Autorzy :
Canter MP; Division of Urogynecology, Department of Obstetrics and Gynecology, Virginia Hospital Center, Arlington, VA 22205, USA. />Graham CA
Heit MH
Blackwell LS
Wilkey DW
Klein JB
Merchant ML
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Źródło :
American journal of obstetrics and gynecology [Am J Obstet Gynecol] 2008 May; Vol. 198 (5), pp. 553.e1-6.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Proteomics*
Cystitis, Interstitial/*diagnosis
Proteins/*analysis
Urine/*chemistry
Adolescent ; Adult ; Aged ; Alpha-Globulins/urine ; Biomarkers/urine ; Blood Proteins/urine ; Cystitis, Interstitial/urine ; Diagnosis, Differential ; Electrophoresis, Polyacrylamide Gel ; Female ; Glycoproteins/urine ; Humans ; Kininogens/urine ; Male ; Middle Aged ; Mucoproteins/urine ; Protein Isoforms ; Proteinase Inhibitory Proteins, Secretory/urine ; Quality of Life ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ; Uromodulin
Czasopismo naukowe
Tytuł :
Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: an approach to understand pathological and biochemical alterations in AD.
Autorzy :
Sultana R; Department of Chemistry, University of Kentucky, Lexington, KY 40506, USA.
Boyd-Kimball D
Poon HF
Cai J
Pierce WM
Klein JB
Merchant M
Markesbery WR
Butterfield DA
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Źródło :
Neurobiology of aging [Neurobiol Aging] 2006 Nov; Vol. 27 (11), pp. 1564-76. Date of Electronic Publication: 2005 Nov 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Alzheimer Disease/*metabolism
Cerebellum/*metabolism
Hippocampus/*metabolism
Proteins/*metabolism
Proteomics/*methods
Aged ; Aged, 80 and over ; Alzheimer Disease/physiopathology ; Blotting, Western ; Electrophoresis, Gel, Two-Dimensional ; Female ; Humans ; Hydrazines ; Immunoprecipitation ; Male ; Mass Spectrometry ; Matched-Pair Analysis ; Oxidation-Reduction ; Oxidative Stress ; Trypsin
Czasopismo naukowe
Tytuł :
Redox proteomic identification of oxidized cardiac proteins in adriamycin-treated mice.
Autorzy :
Chen Y; Graduate Center for Toxicology, University of Kentucky, Lexington, KY 40506, USA.
Daosukho C
Opii WO
Turner DM
Pierce WM
Klein JB
Vore M
Butterfield DA
St Clair DK
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2006 Nov 01; Vol. 41 (9), pp. 1470-7. Date of Electronic Publication: 2006 Aug 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Oxidative Stress*
Proteomics*
Antibiotics, Antineoplastic/*pharmacology
Doxorubicin/*pharmacology
Heart/*physiology
Proteins/*metabolism
Animals ; Blotting, Western ; Electrophoresis, Gel, Two-Dimensional ; Heart/drug effects ; Hydrogen Peroxide/pharmacology ; Male ; Mass Spectrometry ; Mice ; Mice, Inbred C57BL ; Oxidants/pharmacology ; Oxidation-Reduction ; Proteins/chemistry
Czasopismo naukowe
Tytuł :
Proteomic identification of less oxidized brain proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at the Abeta region of amyloid precursor protein.
Autorzy :
Poon HF; Department of Chemistry, Center of Membrane Sciences, and Sander-Brown Center on Aging, University of Kentucky, Lexington, KY 40506-0055, USA.
Farr SA
Banks WA
Pierce WM
Klein JB
Morley JE
Butterfield DA
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Źródło :
Brain research. Molecular brain research [Brain Res Mol Brain Res] 2005 Jul 29; Vol. 138 (1), pp. 8-16.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Amyloid beta-Protein Precursor/*genetics
Amyloid beta-Protein Precursor/*metabolism
Brain/*drug effects
Oligonucleotides, Antisense/*pharmacology
Proteins/*metabolism
Proteomics/*methods
Acetaldehyde/analogs & derivatives ; Aging/genetics ; Amyloid beta-Protein Precursor/biosynthesis ; Animals ; Blotting, Western/methods ; Brain/metabolism ; Electrophoresis, Gel, Two-Dimensional/methods ; Mass Spectrometry/methods ; Mice ; Mice, Inbred Strains ; Models, Biological
Czasopismo naukowe
Tytuł :
Proteomic identification of proteins oxidized by Abeta(1-42) in synaptosomes: implications for Alzheimer's disease.
Autorzy :
Boyd-Kimball D; Department of Chemistry, Center for Membrane Sciences, University of Kentucky, Lexington, KY 40506-0055, USA.
Castegna A
Sultana R
Poon HF
Petroze R
Lynn BC
Klein JB
Butterfield DA
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Źródło :
Brain research [Brain Res] 2005 May 24; Vol. 1044 (2), pp. 206-15. Date of Electronic Publication: 2005 Apr 15.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Amyloid beta-Peptides/*toxicity
Brain/*cytology
Peptide Fragments/*toxicity
Proteins/*metabolism
Proteomics/*methods
Synaptosomes/*drug effects
Analysis of Variance ; Animals ; Blotting, Western ; Electrophoresis, Gel, Two-Dimensional/methods ; Gerbillinae ; Male ; Mass Spectrometry ; Oxidation-Reduction/drug effects ; Proteins/drug effects ; Sequence Analysis, Protein ; Synaptosomes/metabolism
Czasopismo naukowe
Tytuł :
Gamma-glutamylcysteine ethyl ester protection of proteins from Abeta(1-42)-mediated oxidative stress in neuronal cell culture: a proteomics approach.
Autorzy :
Boyd-Kimball D; Department of Chemistry, Center for Membrane Sciences, University of Kentucky, Lexington, Kentucky 40506-0055, USA.
Sultana R
Poon HF
Mohmmad-Abdul H
Lynn BC
Klein JB
Butterfield DA
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Źródło :
Journal of neuroscience research [J Neurosci Res] 2005 Mar 01; Vol. 79 (5), pp. 707-13.
Typ publikacji :
Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Amyloid beta-Peptides/*antagonists & inhibitors
Dipeptides/*pharmacology
Neurons/*drug effects
Neuroprotective Agents/*pharmacology
Oxidative Stress/*drug effects
Peptide Fragments/*antagonists & inhibitors
Proteins/*metabolism
Amyloid beta-Peptides/toxicity ; Animals ; Cells, Cultured ; Drug Interactions ; Electrophoresis, Gel, Two-Dimensional/methods ; Embryo, Mammalian ; Gene Expression Regulation/drug effects ; Immunoblotting/methods ; Immunohistochemistry/methods ; Mass Spectrometry/methods ; Neurons/metabolism ; Oxidative Stress/physiology ; Peptide Fragments/toxicity ; Proteomics/methods ; Rats ; Rats, Sprague-Dawley ; Sequence Analysis, Protein/methods
Czasopismo naukowe
Tytuł :
Analysis of expression and posttranslational modification of proteins during hypoxia.
Autorzy :
Kumar GK; Department of Biochemistry, School of Medicine, Case Western Reserve University, Cleveland, OH 44106-4935, USA. />Klein JB
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Źródło :
Journal of applied physiology (Bethesda, Md. : 1985) [J Appl Physiol (1985)] 2004 Mar; Vol. 96 (3), pp. 1178-86; discussion 1170-2.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, P.H.S.; Review
MeSH Terms :
Hypoxia/*metabolism
Protein Processing, Post-Translational/*physiology
Proteins/*metabolism
Animals ; Humans ; Proteomics/methods
Czasopismo naukowe
Tytuł :
Proteomic identification of nitrated proteins in Alzheimer's disease brain.
Autorzy :
Castegna A; Department of Chemistry, Center of Membrane Sciences, University of Kentucky, Lexington, Kentucky 40506-0055, USA.
Thongboonkerd V
Klein JB
Lynn B
Markesbery WR
Butterfield DA
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Źródło :
Journal of neurochemistry [J Neurochem] 2003 Jun; Vol. 85 (6), pp. 1394-401.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Alzheimer Disease*/metabolism
Brain Chemistry*
Proteomics*
Nitrates/*analysis
Proteins/*chemistry
Tyrosine/*analogs & derivatives
Aged ; Aged, 80 and over ; Blotting, Western ; Electrophoresis, Gel, Two-Dimensional ; Female ; Humans ; Male ; Nerve Tissue Proteins/chemistry ; Nitrates/metabolism ; Oxidative Stress ; Peroxynitrous Acid/metabolism ; Phosphopyruvate Hydratase/chemistry ; Proteins/metabolism ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ; Triose-Phosphate Isomerase/chemistry ; Tyrosine/analysis
Czasopismo naukowe
Tytuł :
Proteomic analysis of normal human urinary proteins isolated by acetone precipitation or ultracentrifugation.
Autorzy :
Thongboonkerd V; Core Proteomics Laboratory and Molecular Signaling Group, Kidney Disease Program, Department of Medicine, University of Louisville, 570 South Preston Street, Louisville, KY 40202, USA.
McLeish KR
Arthur JM
Klein JB
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Źródło :
Kidney international [Kidney Int] 2002 Oct; Vol. 62 (4), pp. 1461-9.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Proteomics*
Proteins/*analysis
Urine/*chemistry
Acetone ; Chemical Precipitation ; Computational Biology ; Electrophoresis, Gel, Two-Dimensional ; Humans ; Peptide Mapping ; Serine Endopeptidases ; Solvents ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ; Staining and Labeling ; Tryptases ; Ultracentrifugation
Czasopismo naukowe
Tytuł :
Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71.
Autorzy :
Castegna A; Department of Chemistry, Center of Membrane Sciences, University of Kentucky, Lexington, Kentucky 40506, USA.
Aksenov M
Thongboonkerd V
Klein JB
Pierce WM
Booze R
Markesbery WR
Butterfield DA
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Źródło :
Journal of neurochemistry [J Neurochem] 2002 Sep; Vol. 82 (6), pp. 1524-32.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
HSP70 Heat-Shock Proteins*
Brain/*metabolism
Heat-Shock Proteins/*metabolism
Phosphopyruvate Hydratase/*metabolism
Proteins/*metabolism
Aged ; Aged, 80 and over ; Brain Chemistry ; Electrophoresis, Gel, Two-Dimensional ; Female ; HSC70 Heat-Shock Proteins ; Heat-Shock Proteins/analysis ; Humans ; Intercellular Signaling Peptides and Proteins ; Male ; Mass Spectrometry ; Nerve Tissue Proteins ; Oxidation-Reduction ; Parietal Lobe/metabolism ; Phosphopyruvate Hydratase/analysis ; Proteins/analysis ; Proteome
Czasopismo naukowe

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