- Tytuł:
- Zileuton, 5-lipoxygenase inhibitor, acts as a chemopreventive agent in intestinal polyposis, by modulating polyp and systemic inflammation.
- Autorzy:
- Źródło:
- PloS one [PLoS One] 2015 Mar 06; Vol. 10 (3), pp. e0121402. Date of Electronic Publication: 2015 Mar 06 (Print Publication: 2015).
- Typ publikacji:
- Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Hydroxyurea/*analogs & derivatives
Inflammatory Bowel Diseases/*prevention & control
Intestinal Polyposis/*prevention & control
Lipoxygenase Inhibitors/*pharmacology
Animals ; Colonic Neoplasms/pathology ; Colonic Neoplasms/prevention & control ; Disease Models, Animal ; Female ; Humans ; Hydroxyurea/pharmacology ; Inflammatory Bowel Diseases/pathology ; Intestinal Polyposis/pathology ; Male ; Mice ; Mice, Mutant Strains
Czasopismo naukowe