- Tytuł:
-
Melatonin attenuates hypertension-related proarrhythmic myocardial maladaptation of connexin-43 and propensity of the heart to lethal arrhythmias. - Autorzy:
- Źródło:
- Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2013 Aug; Vol. 91 (8), pp. 633-9. Date of Electronic Publication: 2013 Jan 25.
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
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Arrhythmias, Cardiac/*prevention & control
Cardiotonic Agents/*therapeutic use
Connexin 43/*metabolism
Hypertension/*drug therapyMelatonin /*therapeutic use
Myocardium/*metabolism
Adaptation, Physiological/drug effects ; Animals ; Arrhythmias, Cardiac/etiology ; Arrhythmias, Cardiac/metabolism ; Arrhythmias, Cardiac/pathology ; Blotting, Western ; Cardiotonic Agents/adverse effects ; Cardiotonic Agents/blood ; Connexin 43/biosynthesis ; Hypertension/complications ; Hypertension/metabolism ; Hypertension/pathology ;Melatonin /administration & dosage ;Melatonin /blood ; Protein Kinase C/metabolism ; Rats ; Rats, Inbred SHR ; Rats, Wistar ; Real-Time Polymerase Chain Reaction ; Signal Transduction
Czasopismo naukowe