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Tytuł:
P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss.
Autorzy:
Stefanski HE; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States of America.
Xing Y; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States of America.
Nicholls J; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States of America.
Jonart L; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States of America.
Goren E; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States of America.
Taylor PA; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States of America.
Mills AA; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, New York, United States of America.
Riddle M; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States of America.
McGrath J; Molecular Dermatology, St John's Institute of Dermatology, King's College, London, England.
Tolar J; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States of America.
Hollander GA; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.; Department of Biomedicine, Basel University Children's Hospital, University of Basel, Basel, Switzerland.; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
Blazar BR; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States of America.
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Źródło:
PloS one [PLoS One] 2022 Jan 25; Vol. 17 (1), pp. e0261770. Date of Electronic Publication: 2022 Jan 25 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Gene Deletion*
Gene Knockout Techniques*
Promoter Regions, Genetic*
Alopecia/*genetics
Forkhead Transcription Factors/*genetics
Thymus Gland/*growth & development
Trans-Activators/*deficiency
Alopecia/metabolism ; Animals ; Forkhead Transcription Factors/metabolism ; Mice ; Mice, Knockout ; Trans-Activators/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CRISPR/Cas9 generated knockout mice lacking phenylalanine hydroxylase protein as a novel preclinical model for human phenylketonuria.
Autorzy:
Singh K; Global Discovery Pathology, Translational In-Vivo Models Research Platform, Sanofi, 5 The Mountain Road, Framingham, MA, 01701, USA.; WuXi AppTec Inc., 8th Floor, 55 Cambridge Parkway, Cambridge, MA, 02142, USA.
Cornell CS; Genomic Medicine Unit, Sanofi, 49 New York Avenue, Framingham, MA, 01701, USA.
Jackson R; Genomic Medicine Unit, Sanofi, 49 New York Avenue, Framingham, MA, 01701, USA.
Kabiri M; Transgenic Model and Technology, Translational In-Vivo Research Platform, Industrie Park Hoechst, Sanofi, Frankfurt, Germany.
Phipps M; Transgenic Model and Technology, Translational In-Vivo Models Research Platform, Sanofi, 5 The Mountain Road, Framingham, MA, 01701, USA.
Desai M; Global Bioimaging, Translational In-Vivo Models Research Platform, Sanofi, Framingham, MA, 01701, USA.
Fogle R; Global Bioimaging, Translational In-Vivo Models Research Platform, Sanofi, Framingham, MA, 01701, USA.
Ying X; Global Bioimaging, Translational In-Vivo Models Research Platform, Sanofi, Framingham, MA, 01701, USA.
Anarat-Cappillino G; Pre-Development Sciences NA, Analytical R&D, Sanofi, Framingham, MA, 01701, USA.
Geller S; Pre-Development Sciences NA, Analytical R&D, Sanofi, Framingham, MA, 01701, USA.
Johnson J; Global Discovery Pathology, Translational In-Vivo Models Research Platform, Sanofi, 5 The Mountain Road, Framingham, MA, 01701, USA.
Roberts E; Global Discovery Pathology, Translational In-Vivo Models Research Platform, Sanofi, 5 The Mountain Road, Framingham, MA, 01701, USA.
Malley K; Global Discovery Pathology, Translational In-Vivo Models Research Platform, Sanofi, 5 The Mountain Road, Framingham, MA, 01701, USA.
Devlin T; Transgenic Model and Technology, Translational In-Vivo Models Research Platform, Sanofi, 5 The Mountain Road, Framingham, MA, 01701, USA.
DeRiso M; Transgenic Model and Technology, Translational In-Vivo Models Research Platform, Sanofi, 5 The Mountain Road, Framingham, MA, 01701, USA.
Berthelette P; Genomic Medicine Unit, Sanofi, 49 New York Avenue, Framingham, MA, 01701, USA.
Zhang YV; Genomic Medicine Unit, Sanofi, 49 New York Avenue, Framingham, MA, 01701, USA.
Ryan S; Global Discovery Pathology, Translational In-Vivo Models Research Platform, Sanofi, 5 The Mountain Road, Framingham, MA, 01701, USA.
Rao S; Translational In-Vivo Models Research Platform, Sanofi, 49 New York Avenue, Framingham, MA, 01701, USA.
Thurberg BL; Global Discovery Pathology, Translational In-Vivo Models Research Platform, Sanofi, 5 The Mountain Road, Framingham, MA, 01701, USA.
Bangari DS; Global Discovery Pathology, Translational In-Vivo Models Research Platform, Sanofi, 5 The Mountain Road, Framingham, MA, 01701, USA. .
Kyostio-Moore S; Genomic Medicine Unit, Sanofi, 49 New York Avenue, Framingham, MA, 01701, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Mar 31; Vol. 11 (1), pp. 7254. Date of Electronic Publication: 2021 Mar 31.
Typ publikacji:
Journal Article
MeSH Terms:
CRISPR-Cas Systems*
Disease Models, Animal*
Gene Knockout Techniques*
Phenylalanine Hydroxylase/*genetics
Phenylketonurias/*genetics
Animals ; Male ; Mice ; Mice, Knockout
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Establishment of a hybrid model of atherosclerosis and acute colitis in ApoE-/- mice.
Autorzy:
Chen K; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.; Department of Ultrasound, Nanjing Drum Tower Hospital, Nanjing, P. R. China.
Zhang S; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.
Cui G; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.
Zhang X; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.
Song Y; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.; Department of Ultrasound, Foshan First People's Hospital, Foshan, P. R. China.
Zheng J; Department of Traditional Chinese Medicine, Peking University Shenzhen Hospital, Shenzhen, P. R. China.
Chen Y; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.
Zheng T; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.
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Źródło:
PloS one [PLoS One] 2024 Mar 18; Vol. 19 (3), pp. e0289820. Date of Electronic Publication: 2024 Mar 18 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Atherosclerosis*/diagnostic imaging
Atherosclerosis*/genetics
Plaque, Atherosclerotic*/diagnostic imaging
Plaque, Atherosclerotic*/complications
Colitis*/complications
Inflammatory Bowel Diseases*/complications
Humans ; Mice ; Animals ; Mice, Knockout ; Mice, Knockout, ApoE ; Diet, High-Fat/adverse effects ; Apolipoproteins E/genetics ; Mice, Inbred C57BL ; Disease Models, Animal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dedicated transcriptomics combined with power analysis lead to functional understanding of genes with weak phenotypic changes in knockout lines.
Autorzy:
Xie C; Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Plön, Germany.
Bekpen C; Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Plön, Germany.
Künzel S; Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Plön, Germany.
Keshavarz M; Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Plön, Germany.
Krebs-Wheaton R; Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Plön, Germany.
Skrabar N; Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Plön, Germany.
Ullrich KK; Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Plön, Germany.
Zhang W; Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Plön, Germany.
Tautz D; Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Plön, Germany.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2020 Nov 12; Vol. 16 (11), pp. e1008354. Date of Electronic Publication: 2020 Nov 12 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms:
Gene Knockout Techniques*
Gene Expression Profiling/*methods
Genetic Association Studies/*methods
Animals ; Behavior, Animal ; Computational Biology ; Extremities/anatomy & histology ; Female ; Gene Expression Profiling/statistics & numerical data ; Genetic Association Studies/statistics & numerical data ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Models, Genetic ; Phenotype ; Proof of Concept Study ; RNA-Seq/statistics & numerical data ; Transcriptome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Analyses of Conditional Knockout Mice for Pogz , a Gene Responsible for Neurodevelopmental Disorders in Excitatory and Inhibitory Neurons in the Brain.
Autorzy:
Hamada N; Department of Molecular Neurobiology, Institute for Developmental Research, Aichi Developmental Disability Center, 713-8 Kamiya, Kasugai 480-0392, Japan.
Nishijo T; Department of Molecular Neurobiology, Institute for Developmental Research, Aichi Developmental Disability Center, 713-8 Kamiya, Kasugai 480-0392, Japan.
Iwamoto I; Department of Molecular Neurobiology, Institute for Developmental Research, Aichi Developmental Disability Center, 713-8 Kamiya, Kasugai 480-0392, Japan.
Shifman S; Department of Genetics, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Nagata KI; Department of Molecular Neurobiology, Institute for Developmental Research, Aichi Developmental Disability Center, 713-8 Kamiya, Kasugai 480-0392, Japan.; Department of Neurochemistry, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.
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Źródło:
Cells [Cells] 2024 Mar 19; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Intellectual Disability*/genetics
Neurodevelopmental Disorders*/genetics
Animals ; Humans ; Mice ; Brain ; Mice, Knockout ; Neurons/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dclre1c -Mutation-Induced Immunocompromised Mice Are a Novel Model for Human Xenograft Research.
Autorzy:
Bin Y; Department of Cell Biology, National Translational Science Center for Molecular Medicine, Fourth Military Medical University, Xi'an 710032, China.; State Key Laboratory of New Targets Discovery and Drug Development for Major Diseases, Fourth Military Medical University, Xi'an 710032, China.; School of Basic Medical Sciences, Shaanxi University of Chinese Medicine, Xianyang 712046, China.
Wei S; Department of Obstetrics and Gynecology, Reproductive Medicine Center, Tang Du Hospital, Fourth Military Medical University, Xi'an 710038, China.
Chen R; Department of Cell Biology, National Translational Science Center for Molecular Medicine, Fourth Military Medical University, Xi'an 710032, China.; State Key Laboratory of New Targets Discovery and Drug Development for Major Diseases, Fourth Military Medical University, Xi'an 710032, China.
Zhang H; Department of Occupational & Environmental Health and the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
Ren J; Department of Cell Biology, National Translational Science Center for Molecular Medicine, Fourth Military Medical University, Xi'an 710032, China.; State Key Laboratory of New Targets Discovery and Drug Development for Major Diseases, Fourth Military Medical University, Xi'an 710032, China.; School of Basic Medical Sciences, Shaanxi University of Chinese Medicine, Xianyang 712046, China.
Liu P; Department of Cell Biology, National Translational Science Center for Molecular Medicine, Fourth Military Medical University, Xi'an 710032, China.; State Key Laboratory of New Targets Discovery and Drug Development for Major Diseases, Fourth Military Medical University, Xi'an 710032, China.
Xin Z; Department of Cell Biology, National Translational Science Center for Molecular Medicine, Fourth Military Medical University, Xi'an 710032, China.; State Key Laboratory of New Targets Discovery and Drug Development for Major Diseases, Fourth Military Medical University, Xi'an 710032, China.
Zhang T; Department of Cell Biology, National Translational Science Center for Molecular Medicine, Fourth Military Medical University, Xi'an 710032, China.; State Key Laboratory of New Targets Discovery and Drug Development for Major Diseases, Fourth Military Medical University, Xi'an 710032, China.
Yang H; Department of Cell Biology, National Translational Science Center for Molecular Medicine, Fourth Military Medical University, Xi'an 710032, China.; State Key Laboratory of New Targets Discovery and Drug Development for Major Diseases, Fourth Military Medical University, Xi'an 710032, China.
Wang K; Department of Cell Biology, National Translational Science Center for Molecular Medicine, Fourth Military Medical University, Xi'an 710032, China.; State Key Laboratory of New Targets Discovery and Drug Development for Major Diseases, Fourth Military Medical University, Xi'an 710032, China.
Feng Z; Department of Cell Biology, National Translational Science Center for Molecular Medicine, Fourth Military Medical University, Xi'an 710032, China.; State Key Laboratory of New Targets Discovery and Drug Development for Major Diseases, Fourth Military Medical University, Xi'an 710032, China.
Sun X; Department of Cell Biology, National Translational Science Center for Molecular Medicine, Fourth Military Medical University, Xi'an 710032, China.; State Key Laboratory of New Targets Discovery and Drug Development for Major Diseases, Fourth Military Medical University, Xi'an 710032, China.
Chen Z; Department of Cell Biology, National Translational Science Center for Molecular Medicine, Fourth Military Medical University, Xi'an 710032, China.; State Key Laboratory of New Targets Discovery and Drug Development for Major Diseases, Fourth Military Medical University, Xi'an 710032, China.
Zhang H; Department of Cell Biology, National Translational Science Center for Molecular Medicine, Fourth Military Medical University, Xi'an 710032, China.; State Key Laboratory of New Targets Discovery and Drug Development for Major Diseases, Fourth Military Medical University, Xi'an 710032, China.
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Źródło:
Biomolecules [Biomolecules] 2024 Feb 02; Vol. 14 (2). Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:
Journal Article
MeSH Terms:
Endonucleases*/genetics
Leukocytes, Mononuclear*
Nuclear Proteins*/genetics
Transplantation, Heterologous*
Immunocompromised Host*/genetics
Animals ; Humans ; Mice ; Heterografts ; Mice, Inbred NOD ; Mice, Knockout ; Mice, SCID ; Mutation ; Models, Animal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Generation of prolactin-inducible protein (Pip) knockout mice by CRISPR/Cas9-mediated gene engineering.
Autorzy:
Terceiro LEL; Department of Pathology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada.
Blanchard AAA; Department of Pathology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada.
Edechi CA; Department of Pathology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada.
Freznosa A; Department of Biochemistry and Medical Genetics, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 0T5, Canada.
Triggs-Raine B; Department of Biochemistry and Medical Genetics, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 0T5, Canada.
Leygue E; Department of Biochemistry and Medical Genetics, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 0T5, Canada.; CancerCareManitoba Research Institute, Winnipeg, MB R3E 0V9, Canada.
Myal Y; Department of Pathology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada.; Department of Physiology and Pathophysiology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.; CancerCareManitoba Research Institute, Winnipeg, MB R3E 0V9, Canada.
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2022 Jan; Vol. 100 (1), pp. 86-91. Date of Electronic Publication: 2021 Aug 11.
Typ publikacji:
Journal Article
MeSH Terms:
Mice, Knockout*
CRISPR-Associated Protein 9/*genetics
CRISPR-Cas Systems/*genetics
Gene Knockout Techniques/*methods
Genetic Engineering/*methods
Proteins/*genetics
Animals ; Mice, Inbred C57BL ; Models, Animal ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
ZFP541 and KCTD19 regulate chromatin organization and transcription programs for male meiotic progression.
Autorzy:
Zhou, Xu (AUTHOR)
Fang, Kailun (AUTHOR)
Liu, Yanlei (AUTHOR)
Li, Weidong (AUTHOR)
Tan, Yingjin (AUTHOR)
Zhang, Jiaming (AUTHOR)
Yu, Xiaoxia (AUTHOR)
Wang, Guoqiang (AUTHOR)
Zhang, Yanan (AUTHOR)
Shang, Yongliang (AUTHOR)
Zhang, Liangran (AUTHOR)
Chen, Charlie Degui (AUTHOR)
Wang, Shunxin (AUTHOR)
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Źródło:
Cell Proliferation. Apr2024, Vol. 57 Issue 4, p1-21. 21p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Kir4.1 channels contribute to astrocyte CO2/H-sensitivity and the drive to breathe.
Autorzy:
Cleary, Colin M. (AUTHOR)
Browning, Jack L. (AUTHOR)
Armbruster, Moritz (AUTHOR)
Sobrinho, Cleyton R. (AUTHOR)
Strain, Monica L. (AUTHOR)
Jahanbani, Sarvin (AUTHOR)
Soto-Perez, Jaseph (AUTHOR)
Hawkins, Virginia E. (AUTHOR)
Dulla, Chris G. (AUTHOR)
Olsen, Michelle L. (AUTHOR)
Mulkey, Daniel K. (AUTHOR)
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Źródło:
Communications Biology. 3/28/2024, Vol. 7 Issue 1, p1-13. 13p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Divergent role of Mitochondrial Amidoxime Reducing Component 1 (MARC1) in human and mouse.
Autorzy:
Smagris, Eriks (AUTHOR)
Shihanian, Lisa M. (AUTHOR)
Mintah, Ivory J. (AUTHOR)
Bigdelou, Parnian (AUTHOR)
Livson, Yuliya (AUTHOR)
Brown, Heather (AUTHOR)
Verweij, Niek (AUTHOR)
Hunt, Charleen (AUTHOR)
Johnson, Reid O'Brien (AUTHOR)
Greer, Tyler J. (AUTHOR)
Hartford, Suzanne A. (AUTHOR)
Hindy, George (AUTHOR)
Sun, Luanluan (AUTHOR)
Nielsen, Jonas B. (AUTHOR)
Halasz, Gabor (AUTHOR)
Lotta, Luca A. (AUTHOR)
Murphy, Andrew J. (AUTHOR)
Sleeman, Mark W. (AUTHOR)
Gusarova, Viktoria (AUTHOR)
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Źródło:
PLoS Genetics. 3/4/2024, Vol. 20 Issue 3, p1-28. 28p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ischemia‐induced cardiac dysfunction is exacerbated in adiponectin‐knockout mice due to impaired autophagy flux.
Autorzy:
Sung, Hye Kyoung (AUTHOR)
Tang, Jialing (AUTHOR)
Jahng, James Won Suk (AUTHOR)
Song, Erfei (AUTHOR)
Chan, Yee Kwan (AUTHOR)
Lone, Abdul Hadee (AUTHOR)
Peterson, Jeffrey (AUTHOR)
Abdul‐Sater, Ali (AUTHOR)
Sweeney, Gary (AUTHOR)
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Źródło:
CTS: Clinical & Translational Science. Mar2024, Vol. 17 Issue 3, p1-19. 19p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Sarm1 knockout protects against early but not late axonal degeneration in experimental allergic encephalomyelitis.
Autorzy:
Viar K; Department of Neurology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America.
Njoku D; Department of Neurology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America.
Secor McVoy J; Department of Neurology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America.
Oh U; Department of Neurology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America.
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Źródło:
PloS one [PLoS One] 2020 Jun 25; Vol. 15 (6), pp. e0235110. Date of Electronic Publication: 2020 Jun 25 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Armadillo Domain Proteins*/genetics
Armadillo Domain Proteins*/metabolism
Axons*/metabolism
Axons*/pathology
Cytoskeletal Proteins*/genetics
Cytoskeletal Proteins*/metabolism
Encephalomyelitis, Autoimmune, Experimental*/genetics
Encephalomyelitis, Autoimmune, Experimental*/metabolism
Encephalomyelitis, Autoimmune, Experimental*/pathology
Encephalomyelitis, Autoimmune, Experimental*/prevention & control
Gene Knockout Techniques*
Spinal Cord*/metabolism
Spinal Cord*/pathology
Animals ; Mice ; Mice, Knockout ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
SIRT3 regulates cardiolipin biosynthesis in pressure overload-induced cardiac remodeling by PPARγ-mediated mechanism.
Autorzy:
Liu LX; National Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China.
Zheng XH; National Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China.
Hai JH; National Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China.
Zhang CM; National Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China.
Ti Y; National Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China.
Chen TS; National Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China.
Bu PL; National Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China.
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Źródło:
PloS one [PLoS One] 2024 Apr 16; Vol. 19 (4), pp. e0301990. Date of Electronic Publication: 2024 Apr 16 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Sirtuin 3*/genetics
Sirtuin 3*/metabolism
Mice ; Animals ; PPAR gamma/metabolism ; Cardiolipins/metabolism ; Ventricular Remodeling ; Myocytes, Cardiac/metabolism ; Mice, Knockout
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Quinic acid regulated TMA/TMAO-related lipid metabolism and vascular endothelial function through gut microbiota to inhibit atherosclerotic.
Autorzy:
Jin Q; Department of Cardiovascular Medicine, Hengyang Medical School, The Changsha central Affiliated Hospital, University of South China, Changsha, Hunan, 410004, China.; Department of Cardiovascular Medicine, The Third Xiangya Hospital of Central South University, Changsha, Hunan Province, 410013, China.
Zhang C; Department of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Chen R; Department of Cardiovascular Medicine, Hengyang Medical School, The Changsha central Affiliated Hospital, University of South China, Changsha, Hunan, 410004, China.
Jiang L; Department of Cardiovascular Medicine, Hengyang Medical School, The Changsha central Affiliated Hospital, University of South China, Changsha, Hunan, 410004, China.
Li H; Department of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, 410000, China.
Wu P; Department of Cardiovascular Medicine, Hengyang Medical School, The Changsha central Affiliated Hospital, University of South China, Changsha, Hunan, 410004, China. .
Li L; Department of Cardiovascular Medicine, Hengyang Medical School, The Changsha central Affiliated Hospital, University of South China, Changsha, Hunan, 410004, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Apr 15; Vol. 22 (1), pp. 352. Date of Electronic Publication: 2024 Apr 15.
Typ publikacji:
Journal Article
MeSH Terms:
HMGB1 Protein*/metabolism
Gastrointestinal Microbiome*
Atherosclerosis*/pathology
Methylamines*
Mice ; Animals ; Proprotein Convertase 9 ; Quinic Acid ; Sterol Regulatory Element Binding Protein 1/metabolism ; Tissue Inhibitor of Metalloproteinase-1/metabolism ; Lipid Metabolism ; Mice, Knockout, ApoE ; Inflammation ; Cholesterol ; Apolipoproteins E/metabolism ; Mice, Inbred C57BL
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Loss of ZNF451 mediates fibroblast activation and promotes lung fibrosis.
Autorzy:
Peng H; Department of Pulmonary and Critical Care Medicine, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
Zhang Y; National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, Changsha, Hunan, 410011, China.; Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
Min J; National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, Changsha, Hunan, 410011, China.; Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
Tan Y; Department of Pulmonary and Critical Care Medicine, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
Liu S; National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, Changsha, Hunan, 410011, China. .; Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China. .
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Źródło:
Respiratory research [Respir Res] 2024 Apr 10; Vol. 25 (1), pp. 160. Date of Electronic Publication: 2024 Apr 10.
Typ publikacji:
Journal Article
MeSH Terms:
Pulmonary Fibrosis*/chemically induced
Pulmonary Fibrosis*/genetics
Pulmonary Fibrosis*/metabolism
Animals ; Mice ; Bleomycin/toxicity ; Fibroblasts/metabolism ; Lung/metabolism ; Mice, Knockout ; Phosphatidylinositol 3-Kinases/metabolism ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
GDF-15 Suppresses Puromycin Aminonucleoside-Induced Podocyte Injury by Reducing Endoplasmic Reticulum Stress and Glomerular Inflammation.
Autorzy:
von Rauchhaupt E; Department of Medicine IV, Renal Division, Ludwig-Maximilians-University Hospital, Ludwig-Maximilians-University Munich, 80336 Munich, Germany.
Klaus M; Department of Medicine IV, Renal Division, Ludwig-Maximilians-University Hospital, Ludwig-Maximilians-University Munich, 80336 Munich, Germany.
Ribeiro A; Department of Medicine IV, Renal Division, Ludwig-Maximilians-University Hospital, Ludwig-Maximilians-University Munich, 80336 Munich, Germany.; Klinikum Rechts der Isar, Department of Nephrology, Technical University Munich, 81675 Munich, Germany.
Honarpisheh M; Department of Medicine IV, Renal Division, Ludwig-Maximilians-University Hospital, Ludwig-Maximilians-University Munich, 80336 Munich, Germany.
Li C; Department of Medicine IV, Renal Division, Ludwig-Maximilians-University Hospital, Ludwig-Maximilians-University Munich, 80336 Munich, Germany.
Liu M; Department of Medicine IV, Renal Division, Ludwig-Maximilians-University Hospital, Ludwig-Maximilians-University Munich, 80336 Munich, Germany.
Köhler P; Department of Medicine IV, Renal Division, Ludwig-Maximilians-University Hospital, Ludwig-Maximilians-University Munich, 80336 Munich, Germany.
Adamowicz K; Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology of Jagiellonian University, 30-387 Krakow, Poland.
Schmaderer C; Klinikum Rechts der Isar, Department of Nephrology, Technical University Munich, 81675 Munich, Germany.
Lindenmeyer M; III Department of Medicine, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Steiger S; Department of Medicine IV, Renal Division, Ludwig-Maximilians-University Hospital, Ludwig-Maximilians-University Munich, 80336 Munich, Germany.
Anders HJ; Department of Medicine IV, Renal Division, Ludwig-Maximilians-University Hospital, Ludwig-Maximilians-University Munich, 80336 Munich, Germany.
Lech M; Department of Medicine IV, Renal Division, Ludwig-Maximilians-University Hospital, Ludwig-Maximilians-University Munich, 80336 Munich, Germany.
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Źródło:
Cells [Cells] 2024 Apr 05; Vol. 13 (7). Date of Electronic Publication: 2024 Apr 05.
Typ publikacji:
Journal Article
MeSH Terms:
Podocytes*/metabolism
Kidney Diseases*/metabolism
Humans ; Mice ; Animals ; Puromycin Aminonucleoside/adverse effects ; Puromycin Aminonucleoside/metabolism ; Growth Differentiation Factor 15/genetics ; Growth Differentiation Factor 15/metabolism ; Creatinine/metabolism ; Inflammation/metabolism ; Mice, Knockout
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Apoptotic cell identity induces distinct functional responses to IL-4 in efferocytic macrophages.
Autorzy:
Liebold I; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Al Jawazneh A; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Casar C; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Bioinformatics Core, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Lanzloth C; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Leyk S; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Hamley M; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Wong MN; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Department of Pathology, Aarhus University Hospital, Aarhus, Denmark.
Kylies D; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Gräfe SK; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Edenhofer I; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Aranda-Pardos I; Institute of Immunology, University of Münster, Münster, Germany.
Kriwet M; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Haas H; helminGuard, Sülfeld/Borstel, Germany.
Krause J; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Hadjilaou A; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; Institute of Neuroimmunology and Multiple Sclerosis, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Schromm AB; Division of Immunobiophysics, Research Center Borstel, Leibniz Lung Center, Borstel, Germany.
Richardt U; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Eggert P; Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Tappe D; Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Weidemann SA; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ghosh S; Department of Neurology, Yale University School of Medicine, New Haven, CT, USA.; Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.
Krebs CF; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
A-Gonzalez N; Institute of Immunology, University of Münster, Münster, Germany.
Worthmann A; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Lohse AW; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN-RARE LIVER), Hamburg, Germany.
Huber S; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Rothlin CV; Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Puelles VG; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Department of Pathology, Aarhus University Hospital, Aarhus, Denmark.
Jacobs T; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Gagliani N; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Bosurgi L; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Apr 05; Vol. 384 (6691), pp. eabo7027. Date of Electronic Publication: 2024 Apr 05.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*/immunology
Interleukin-4*/genetics
Interleukin-4*/metabolism
Macrophages*/immunology
Phagocytosis*/immunology
Schistosomiasis mansoni*/genetics
Schistosomiasis mansoni*/immunology
Animals ; Mice ; Mice, Knockout ; Neutrophils/immunology ; Hepatocytes/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: implications for Alzheimer disease pathogenesis.
Autorzy:
Terron HM; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine (UCI MIND), Irvine, CA, 92697, USA.
Parikh SJ; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine (UCI MIND), Irvine, CA, 92697, USA.
Abdul-Hay SO; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, 32224, USA.
Sahara T; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, 32224, USA.
Kang D; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, 32224, USA.
Dickson DW; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, 32224, USA.
Saftig P; Institut für Biochemie, Christian-Albrechts-Universität zu Kiel, D-24098, Kiel, Germany.
LaFerla FM; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine (UCI MIND), Irvine, CA, 92697, USA.; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA, 92697, USA.
Lane S; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine (UCI MIND), Irvine, CA, 92697, USA.
Leissring MA; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine (UCI MIND), Irvine, CA, 92697, USA. .; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, 32224, USA. .
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Źródło:
Alzheimer's research & therapy [Alzheimers Res Ther] 2024 Apr 04; Vol. 16 (1), pp. 70. Date of Electronic Publication: 2024 Apr 04.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/pathology
Tauopathies*/genetics
Tauopathies*/metabolism
Aged ; Animals ; Humans ; Mice ; Amyloid beta-Peptides/metabolism ; Amyloid beta-Protein Precursor/genetics ; Amyloid beta-Protein Precursor/metabolism ; Cathepsin D ; Disease Models, Animal ; Mice, Knockout ; Mice, Transgenic ; tau Proteins/genetics ; tau Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Claudin-10 Expression and the Gene Expression Pattern of Thick Ascending Limb Cells.
Autorzy:
Brideau G; Centre de Recherche des Cordeliers, Institut National de la Santé et de la Recherche Médicale, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.; Centre National de la Recherche Scientifique, Equipe Mixte de Recherche 8228-Laboratoire de Physiologie Rénale et Tubulopathies, F-75006 Paris, France.
Cheval L; Centre de Recherche des Cordeliers, Institut National de la Santé et de la Recherche Médicale, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.; Centre National de la Recherche Scientifique, Equipe Mixte de Recherche 8228-Laboratoire de Physiologie Rénale et Tubulopathies, F-75006 Paris, France.
Griveau C; Centre de Recherche des Cordeliers, Institut National de la Santé et de la Recherche Médicale, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.; Centre National de la Recherche Scientifique, Equipe Mixte de Recherche 8228-Laboratoire de Physiologie Rénale et Tubulopathies, F-75006 Paris, France.
Ling WE; Centre de Recherche des Cordeliers, Institut National de la Santé et de la Recherche Médicale, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.; Centre National de la Recherche Scientifique, Equipe Mixte de Recherche 8228-Laboratoire de Physiologie Rénale et Tubulopathies, F-75006 Paris, France.
Lievre L; Centre de Recherche des Cordeliers, Institut National de la Santé et de la Recherche Médicale, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.; Centre National de la Recherche Scientifique, Equipe Mixte de Recherche 8228-Laboratoire de Physiologie Rénale et Tubulopathies, F-75006 Paris, France.
Crambert G; Centre de Recherche des Cordeliers, Institut National de la Santé et de la Recherche Médicale, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.; Centre National de la Recherche Scientifique, Equipe Mixte de Recherche 8228-Laboratoire de Physiologie Rénale et Tubulopathies, F-75006 Paris, France.
Müller D; Department of Pediatrics, Division of Gastroenterology, Nephrology and Metabolic Diseases, Charité-Universitätsmedizin Berlin, DE-13353 Berlin, Germany.
Broćić J; Paris Brain Institute (ICM), Hôpital Pitié-Salpêtrière, Inserm U 1127, CNRS UMR 7225, Sorbonne Université, Data Analysis Core Platform, F-75013 Paris, France.
Cherchame E; Paris Brain Institute (ICM), Hôpital Pitié-Salpêtrière, Inserm U 1127, CNRS UMR 7225, Sorbonne Université, Data Analysis Core Platform, F-75013 Paris, France.
Houillier P; Centre de Recherche des Cordeliers, Institut National de la Santé et de la Recherche Médicale, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.; Centre National de la Recherche Scientifique, Equipe Mixte de Recherche 8228-Laboratoire de Physiologie Rénale et Tubulopathies, F-75006 Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service de Physiologie, F-75015 Paris, France.; Centre de Référence des Maladies Rénales Héréditaires de l'Enfant et de l'Adulte (MARHEA), The European Rare Kidney Disease Reference Network (ERKNet), F-75015 Paris, France.; Centre de Référence des Maladies Rares du Calcium et du Phosphate, The European Reference Network on Rare Endocrine Conditions (Endo-ERN), F-75015 Paris, France.; Faculté de Médecine, Université Paris Cité, F-75006 Paris, France.
Prot-Bertoye C; Centre de Recherche des Cordeliers, Institut National de la Santé et de la Recherche Médicale, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.; Centre National de la Recherche Scientifique, Equipe Mixte de Recherche 8228-Laboratoire de Physiologie Rénale et Tubulopathies, F-75006 Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service de Physiologie, F-75015 Paris, France.; Centre de Référence des Maladies Rénales Héréditaires de l'Enfant et de l'Adulte (MARHEA), The European Rare Kidney Disease Reference Network (ERKNet), F-75015 Paris, France.; Centre de Référence des Maladies Rares du Calcium et du Phosphate, The European Reference Network on Rare Endocrine Conditions (Endo-ERN), F-75015 Paris, France.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 03; Vol. 25 (7). Date of Electronic Publication: 2024 Apr 03.
Typ publikacji:
Journal Article
MeSH Terms:
Extremities*
Adrenal Medulla*
Animals ; Mice ; Claudins/genetics ; Mice, Knockout ; Gene Expression
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tumor Cell-Associated IL-1α Affects Breast Cancer Progression and Metastasis in Mice through Manipulation of the Tumor Immune Microenvironment.
Autorzy:
Krishnamohan M; The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.
Kaplanov I; The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.
Maudi-Boker S; The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.
Yousef M; The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.
Machluf-Katz N; The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.
Cohen I; Cancer Center, Emek Medical Center, Afula 18101, Israel.
Elkabets M; The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.
Titus J; The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.
Bersudsky M; The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.
Apte RN; The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.
Voronov E; The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.
Braiman A; The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 02; Vol. 25 (7). Date of Electronic Publication: 2024 Apr 02.
Typ publikacji:
Journal Article
MeSH Terms:
Triple Negative Breast Neoplasms*/genetics
Lung Neoplasms*/genetics
Animals ; Mice ; Humans ; Mice, Inbred NOD ; Mice, Knockout ; Mice, SCID ; Tumor Microenvironment ; Interleukin-1alpha/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
RIO-kinase 2 is essential for hematopoiesis.
Autorzy:
Messling JE; Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark.
Peña-Rømer I; The Institute of Cancer Research, London, United Kingdom.
Moroni AS; Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark.
Bruestl S; The Institute of Cancer Research, London, United Kingdom.
Helin K; The Institute of Cancer Research, London, United Kingdom.
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Źródło:
PloS one [PLoS One] 2024 Apr 02; Vol. 19 (4), pp. e0300623. Date of Electronic Publication: 2024 Apr 02 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Hematopoietic Stem Cells*/metabolism
Leukemia, Myeloid, Acute*/metabolism
Animals ; Humans ; Mice ; Bone Marrow Transplantation ; Cell Differentiation/physiology ; Hematopoiesis/genetics ; Mice, Knockout
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mitochondria-mediated ferroptosis induced by CARD9 ablation prevents MDSCs-dependent antifungal immunity.
Autorzy:
Zhang Z; Department of Endodontic, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Research Institute of Stomatology, Nanjing University, Nanjing, 210008, China.; The State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.
Li P; The State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.
Chen Y; The State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.
Chen Y; The State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.
Wang X; The State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.
Shen S; The State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.
Zhao Y; The State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.
Zhu Y; Department of Endodontic, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Research Institute of Stomatology, Nanjing University, Nanjing, 210008, China. .
Wang T; The State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China. .; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Apr 02; Vol. 22 (1), pp. 210. Date of Electronic Publication: 2024 Apr 02.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloid-Derived Suppressor Cells*
Ferroptosis*
Candidiasis*
Acute Kidney Injury*
Mice ; Animals ; Antifungal Agents ; Mice, Knockout
SCR Disease Name:
Systemic candidiasis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-25 z 62785

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