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    Wyświetlanie 1-3 z 3
    Tytuł:
    Neutrophil fluorescence in clozapine users is attributable to a 14kDa secretable protein.
    Autorzy:
    de With SAJ; Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands.
    Man WH; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Clinical Pharmacy, Meander Medical Center, Amersfoort, The Netherlands.
    Maas C; Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.
    Ten Berg M; Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.
    Cahn W; Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands.
    Koekman AC; Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.
    van Solinge WW; Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.
    Tak T; Department of Respiratory Medicine, Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
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    Źródło:
    Pharmacology research & perspectives [Pharmacol Res Perspect] 2020 Oct; Vol. 8 (5), pp. e00627.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Antipsychotic Agents/*adverse effects
    Clozapine/*adverse effects
    Neutrophils/*metabolism
    Schizophrenia/*drug therapy
    Case-Control Studies ; Clozapine/pharmacology ; Cytochalasin B/pharmacology ; Electrophoresis, Polyacrylamide Gel ; Gene Expression Regulation/drug effects ; Humans ; Luminescent Proteins/analysis ; Luminescent Proteins/chemistry ; Luminescent Proteins/drug effects ; Microscopy, Fluorescence ; Molecular Weight ; Neutrophils/drug effects ; Peptide Fragments/analysis ; Peptide Fragments/chemistry ; Peptide Fragments/drug effects ; Platelet Activating Factor/metabolism ; Schizophrenia/blood
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    The effect of P2Y12 inhibition on platelet activation assessed with aggregation- and flow cytometry-based assays.
    Autorzy:
    Leunissen TC; a Department of Clinical Chemistry and Hematology , University Medical Center Utrecht , The Netherlands.; b Department of Vascular Surgery , University Medical Center Utrecht , The Netherlands.
    Wisman PP; a Department of Clinical Chemistry and Hematology , University Medical Center Utrecht , The Netherlands.; b Department of Vascular Surgery , University Medical Center Utrecht , The Netherlands.
    van Holten TC; a Department of Clinical Chemistry and Hematology , University Medical Center Utrecht , The Netherlands.
    de Groot PG; a Department of Clinical Chemistry and Hematology , University Medical Center Utrecht , The Netherlands.
    Korporaal SJ; a Department of Clinical Chemistry and Hematology , University Medical Center Utrecht , The Netherlands.
    Koekman AC; a Department of Clinical Chemistry and Hematology , University Medical Center Utrecht , The Netherlands.
    Moll FL; b Department of Vascular Surgery , University Medical Center Utrecht , The Netherlands.
    Teraa M; b Department of Vascular Surgery , University Medical Center Utrecht , The Netherlands.; c Department of Nephrology and Hypertension , University Medical Center Utrecht , The Netherlands.
    Verhaar MC; c Department of Nephrology and Hypertension , University Medical Center Utrecht , The Netherlands.
    de Borst GJ; b Department of Vascular Surgery , University Medical Center Utrecht , The Netherlands.
    Urbanus RT; a Department of Clinical Chemistry and Hematology , University Medical Center Utrecht , The Netherlands.
    Roest M; a Department of Clinical Chemistry and Hematology , University Medical Center Utrecht , The Netherlands.
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    Źródło:
    Platelets [Platelets] 2017 Sep; Vol. 28 (6), pp. 567-575. Date of Electronic Publication: 2016 Nov 25.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Flow Cytometry*
    Blood Platelets/*metabolism
    Platelet Aggregation/*drug effects
    Purinergic P2Y Receptor Antagonists/*pharmacology
    Receptors, Purinergic P2Y12/*metabolism
    Blood Platelets/pathology ; Female ; Humans ; Male ; Platelet Function Tests
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Endocannabinoids control platelet activation and limit aggregate formation under flow.
    Autorzy:
    De Angelis V; Department of Clinical Chemistry and Haematology, Utrecht University Medical Center, Utrecht, The Netherlands.
    Koekman AC; Department of Clinical Chemistry and Haematology, Utrecht University Medical Center, Utrecht, The Netherlands.
    Weeterings C; Department of Clinical Chemistry and Haematology, Utrecht University Medical Center, Utrecht, The Netherlands.
    Roest M; Department of Clinical Chemistry and Haematology, Utrecht University Medical Center, Utrecht, The Netherlands.
    de Groot PG; Department of Clinical Chemistry and Haematology, Utrecht University Medical Center, Utrecht, The Netherlands.
    Herczenik E; Department of Clinical Chemistry and Haematology, Utrecht University Medical Center, Utrecht, The Netherlands.
    Maas C; Department of Clinical Chemistry and Haematology, Utrecht University Medical Center, Utrecht, The Netherlands.
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    Źródło:
    PloS one [PLoS One] 2014 Sep 29; Vol. 9 (9), pp. e108282. Date of Electronic Publication: 2014 Sep 29 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Arachidonic Acids/*pharmacology
    Blood Platelets/*metabolism
    Endocannabinoids/*pharmacology
    Platelet Activation/*drug effects
    Platelet Aggregation/*drug effects
    Polyunsaturated Alkamides/*pharmacology
    Thrombosis/*prevention & control
    15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid/pharmacology ; Calcium/metabolism ; Cannabis/metabolism ; Collagen/pharmacology ; Dronabinol/pharmacology ; Fibrinogen/metabolism ; Humans ; Integrin beta3/metabolism ; Intracellular Signaling Peptides and Proteins/metabolism ; Phosphorylation ; Platelet Membrane Glycoprotein IIb/metabolism ; Protein-Tyrosine Kinases/metabolism ; Receptor, Cannabinoid, CB2/agonists ; Receptor, Cannabinoid, CB2/metabolism ; Receptor, PAR-1/metabolism ; Signal Transduction/drug effects ; Syk Kinase ; Thrombosis/drug therapy
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-3 z 3

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