Experience with a hybrid recruitment approach of patient-facing web portal screening and subsequent phone and medical record review for a neurosurgical intervention trial for chronic ischemic stroke disability (PISCES III).
Autorzy:
KollsBJ; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA. .; Department of Neurology, Duke University School of Medicine, Duke Box 2900 Bryan Research Building, 311 Research Drive, Durham, NC, 27710, USA. . Muir KW; School of Psychology & Neuroscience, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, Scotland, UK. Savitz SI; Institute for Stroke and Cerebrovascular Disease, University of Texas Health Science Center, Houston, TX, USA. Wechsler LR; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Pilitsis JG; Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, NY, USA. Rahimi S; Department of Neurosurgery, Medical College of Georgia, Augusta, GA, USA. Beckman RL; ReNeuron Limited., Pencoed, Bridgend, UK. Holmes V; ReNeuron Limited., Pencoed, Bridgend, UK. Chen PR; The Vivian L. Smith Department of Neurosurgery, The University of Texas Health Science Center, Houston, TX, USA. Albers DS; ReNeuron Limited., Pencoed, Bridgend, UK. Laskowitz DT; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Neurology, Duke University School of Medicine, Duke Box 2900 Bryan Research Building, 311 Research Drive, Durham, NC, 27710, USA.
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Źródło:
Trials [Trials] 2024 Feb 28; Vol. 25 (1), pp. 150. Date of Electronic Publication: 2024 Feb 28.
Sustained overexpression of spliced X-box-binding protein-1 in neurons leads to spontaneous seizures and sudden death in mice.
Autorzy:
Wang Z; Multidisciplinary Brain Protection Program, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA. Li Q; Department of Neurology, Duke University Medical Center, Durham, NC, USA. KollsBJ; Department of Neurology, Duke University Medical Center, Durham, NC, USA. Mace B; Department of Neurology, Duke University Medical Center, Durham, NC, USA. Yu S; Multidisciplinary Brain Protection Program, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA. Li X; Multidisciplinary Brain Protection Program, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA. Liu W; Department of Bioengineering, Duke University, Durham, NC, USA. Chaparro E; Department of Neurosurgery, Duke University Medical Center, Durham, NC, USA. Shen Y; Multidisciplinary Brain Protection Program, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA. Dang L; Multidisciplinary Brain Protection Program, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA. Del Águila Á; Multidisciplinary Brain Protection Program, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA. Bernstock JD; National Institute of Neurological Disorders and Stroke, NINDS/NIH, Bethesda, MD, USA. Johnson KR; National Institute of Neurological Disorders and Stroke, NINDS/NIH, Bethesda, MD, USA. Yao J; Department of Bioengineering, Duke University, Durham, NC, USA. Wetsel WC; Department of Neurology, Duke University Medical Center, Durham, NC, USA.; Departments of Neurobiology and Cell Biology, Duke University Medical Center, Durham, NC, USA. Moore SD; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA. Turner DA; Departments of Neurosurgery, Neurobiology and Biomedical Engineering, Duke University Medical Center, Durham, NC, USA. Yang W; Multidisciplinary Brain Protection Program, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA. .; Department of Neurology, Duke University Medical Center, Durham, NC, USA. .
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Źródło:
Communications biology [Commun Biol] 2023 Mar 09; Vol. 6 (1), pp. 252. Date of Electronic Publication: 2023 Mar 09.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
Antagonism of nicotinic acetycholinergic receptors by CN-105, an apoE-mimetic peptide reduces stroke-induced excitotoxicity.
Autorzy:
Xue M; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China. Li S; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China. Xu M; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China. Yan L; ICE Bioscience Inc., Beijing, China. Laskowitz DT; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Neurology, Duke University, Durham, North Carolina, USA.; Department of Anesthesiology, Duke University, Durham, North Carolina, USA.; Aegis-CN, LLC, Durham, North Carolina, USA. KollsBJ; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Neurology, Duke University, Durham, North Carolina, USA. Chen G; Guangdong Cerebtron Biotech Ltd., Guangdong, China. Qian X; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China. Wang Y; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China. Song H; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China. Wang Y; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China.
Neuroprotective pentapeptide CN-105 is associated with reduced sterile inflammation and improved functional outcomes in a traumatic brain injury murine model.
Autorzy:
Laskowitz DT; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Neurobiology, Duke University School of Medicine, Durham, NC 27710, USA.; Aegis-CN LLC., Durham, NC, USA. Wang H; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA. Chen T; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA. Lubkin DT; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA. Cantillana V; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA. Tu TM; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Neurology, National Neuroscience Institute, Tan Tock Seng Hospital, Singapore. Kernagis D; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA. Zhou G; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA. Macy G; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA. KollsBJ; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA. Dawson HN; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.
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Źródło:
Scientific reports [Sci Rep] 2017 Apr 21; Vol. 7, pp. 46461. Date of Electronic Publication: 2017 Apr 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Apolipoprotein E mimetic peptide, CN-105, improves outcomes in ischemic stroke.
Autorzy:
Tu TM; Department of Neurology Duke University School of Medicine Durham North Carolina; Department of Neurology National Neuroscience Institute Tan Tock Seng Campus Singapore. KollsBJ; Department of Neurology Duke University School of Medicine Durham North Carolina. Soderblom EJ; Duke Proteomics Core Facility Center for Genomic and Computational Biology Duke University Durham North Carolina. Cantillana V; Department of Neurology Duke University School of Medicine Durham North Carolina. Ferrell PD; Department of Pathology Duke University School of Medicine Durham North Carolina. Moseley MA; Duke Proteomics Core Facility Center for Genomic and Computational Biology Duke University Durham North Carolina. Wang H; Department of Neurology Duke University School of Medicine Durham North Carolina. Dawson HN; Department of Neurology Duke University School of Medicine Durham North Carolina. Laskowitz DT; Department of Neurology Duke University School of Medicine Durham North Carolina.
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