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Wyświetlanie 1-6 z 6
Tytuł:
Experience with a hybrid recruitment approach of patient-facing web portal screening and subsequent phone and medical record review for a neurosurgical intervention trial for chronic ischemic stroke disability (PISCES III).
Autorzy:
Kolls BJ; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA. .; Department of Neurology, Duke University School of Medicine, Duke Box 2900 Bryan Research Building, 311 Research Drive, Durham, NC, 27710, USA. .
Muir KW; School of Psychology & Neuroscience, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, Scotland, UK.
Savitz SI; Institute for Stroke and Cerebrovascular Disease, University of Texas Health Science Center, Houston, TX, USA.
Wechsler LR; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Pilitsis JG; Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, NY, USA.
Rahimi S; Department of Neurosurgery, Medical College of Georgia, Augusta, GA, USA.
Beckman RL; ReNeuron Limited., Pencoed, Bridgend, UK.
Holmes V; ReNeuron Limited., Pencoed, Bridgend, UK.
Chen PR; The Vivian L. Smith Department of Neurosurgery, The University of Texas Health Science Center, Houston, TX, USA.
Albers DS; ReNeuron Limited., Pencoed, Bridgend, UK.
Laskowitz DT; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Neurology, Duke University School of Medicine, Duke Box 2900 Bryan Research Building, 311 Research Drive, Durham, NC, 27710, USA.
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Źródło:
Trials [Trials] 2024 Feb 28; Vol. 25 (1), pp. 150. Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
Ischemic Stroke*
Stroke*/diagnosis
Stroke*/therapy
Humans ; Patient Selection ; Research Design ; Medical Records
Czasopismo naukowe
Tytuł:
Sustained overexpression of spliced X-box-binding protein-1 in neurons leads to spontaneous seizures and sudden death in mice.
Autorzy:
Wang Z; Multidisciplinary Brain Protection Program, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
Li Q; Department of Neurology, Duke University Medical Center, Durham, NC, USA.
Kolls BJ; Department of Neurology, Duke University Medical Center, Durham, NC, USA.
Mace B; Department of Neurology, Duke University Medical Center, Durham, NC, USA.
Yu S; Multidisciplinary Brain Protection Program, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
Li X; Multidisciplinary Brain Protection Program, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
Liu W; Department of Bioengineering, Duke University, Durham, NC, USA.
Chaparro E; Department of Neurosurgery, Duke University Medical Center, Durham, NC, USA.
Shen Y; Multidisciplinary Brain Protection Program, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
Dang L; Multidisciplinary Brain Protection Program, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
Del Águila Á; Multidisciplinary Brain Protection Program, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
Bernstock JD; National Institute of Neurological Disorders and Stroke, NINDS/NIH, Bethesda, MD, USA.
Johnson KR; National Institute of Neurological Disorders and Stroke, NINDS/NIH, Bethesda, MD, USA.
Yao J; Department of Bioengineering, Duke University, Durham, NC, USA.
Wetsel WC; Department of Neurology, Duke University Medical Center, Durham, NC, USA.; Departments of Neurobiology and Cell Biology, Duke University Medical Center, Durham, NC, USA.
Moore SD; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
Turner DA; Departments of Neurosurgery, Neurobiology and Biomedical Engineering, Duke University Medical Center, Durham, NC, USA.
Yang W; Multidisciplinary Brain Protection Program, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA. .; Department of Neurology, Duke University Medical Center, Durham, NC, USA. .
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Źródło:
Communications biology [Commun Biol] 2023 Mar 09; Vol. 6 (1), pp. 252. Date of Electronic Publication: 2023 Mar 09.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Seizures*/genetics
Unfolded Protein Response*
Animals ; Mice ; Death, Sudden ; Mice, Transgenic ; Neurons
Czasopismo naukowe
Tytuł:
Antagonism of nicotinic acetycholinergic receptors by CN-105, an apoE-mimetic peptide reduces stroke-induced excitotoxicity.
Autorzy:
Xue M; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China.
Li S; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.
Xu M; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China.
Yan L; ICE Bioscience Inc., Beijing, China.
Laskowitz DT; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Neurology, Duke University, Durham, North Carolina, USA.; Department of Anesthesiology, Duke University, Durham, North Carolina, USA.; Aegis-CN, LLC, Durham, North Carolina, USA.
Kolls BJ; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Neurology, Duke University, Durham, North Carolina, USA.
Chen G; Guangdong Cerebtron Biotech Ltd., Guangdong, China.
Qian X; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China.
Wang Y; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.
Song H; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China.
Wang Y; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2022 Jan; Vol. 12 (1), pp. e677.
Typ publikacji:
Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Apolipoproteins E/*antagonists & inhibitors
Neurotoxins/*biosynthesis
Peptide Fragments/*antagonists & inhibitors
Receptors, Nicotinic/*drug effects
Stroke/*complications
Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Apolipoproteins E/therapeutic use ; Humans ; Peptide Fragments/therapeutic use ; Stroke/blood ; Stroke/drug therapy
Raport
Tytuł:
Neuroprotective pentapeptide CN-105 is associated with reduced sterile inflammation and improved functional outcomes in a traumatic brain injury murine model.
Autorzy:
Laskowitz DT; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Neurobiology, Duke University School of Medicine, Durham, NC 27710, USA.; Aegis-CN LLC., Durham, NC, USA.
Wang H; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.
Chen T; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.
Lubkin DT; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.
Cantillana V; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.
Tu TM; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Neurology, National Neuroscience Institute, Tan Tock Seng Hospital, Singapore.
Kernagis D; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.
Zhou G; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.
Macy G; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.
Kolls BJ; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.
Dawson HN; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.
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Źródło:
Scientific reports [Sci Rep] 2017 Apr 21; Vol. 7, pp. 46461. Date of Electronic Publication: 2017 Apr 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Apolipoproteins E/*therapeutic use
Brain Injuries, Traumatic/*drug therapy
Inflammation/*drug therapy
Neuroprotective Agents/*therapeutic use
Peptide Fragments/*therapeutic use
Recovery of Function/*drug effects
Animals ; Apolipoproteins E/pharmacology ; Hippocampus/drug effects ; Mice ; Models, Animal ; Neurons/drug effects ; Neuroprotective Agents/pharmacology ; Peptide Fragments/pharmacology
Czasopismo naukowe
Tytuł:
Apolipoprotein E mimetic peptide, CN-105, improves outcomes in ischemic stroke.
Autorzy:
Tu TM; Department of Neurology Duke University School of Medicine Durham North Carolina; Department of Neurology National Neuroscience Institute Tan Tock Seng Campus Singapore.
Kolls BJ; Department of Neurology Duke University School of Medicine Durham North Carolina.
Soderblom EJ; Duke Proteomics Core Facility Center for Genomic and Computational Biology Duke University Durham North Carolina.
Cantillana V; Department of Neurology Duke University School of Medicine Durham North Carolina.
Ferrell PD; Department of Pathology Duke University School of Medicine Durham North Carolina.
Moseley MA; Duke Proteomics Core Facility Center for Genomic and Computational Biology Duke University Durham North Carolina.
Wang H; Department of Neurology Duke University School of Medicine Durham North Carolina.
Dawson HN; Department of Neurology Duke University School of Medicine Durham North Carolina.
Laskowitz DT; Department of Neurology Duke University School of Medicine Durham North Carolina.
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Źródło:
Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2017 Mar 09; Vol. 4 (4), pp. 246-265. Date of Electronic Publication: 2017 Mar 09 (Print Publication: 2017).
Typ publikacji:
Journal Article
Czasopismo naukowe
    Wyświetlanie 1-6 z 6

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