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    Wyświetlanie 1-12 z 12
    Podgląd okładki
    Tytuł :
    Application of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using an e-cigarette device with MESH™ technology.
    Autorzy :
    Iskandar AR; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland. .
    Zanetti F; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Marescotti D; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Titz B; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Sewer A; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Kondylis A; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Leroy P; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Belcastro V; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Torres LO; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Acali S; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Majeed S; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Steiner S; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Trivedi K; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Guedj E; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Merg C; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Schneider T; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Frentzel S; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Martin F; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Ivanov NV; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Peitsch MC; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Hoeng J; Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.
    Pokaż więcej
    Źródło :
    Archives of toxicology [Arch Toxicol] 2019 Nov; Vol. 93 (11), pp. 3229-3247. Date of Electronic Publication: 2019 Sep 07.
    Typ publikacji :
    Journal Article
    MeSH Terms :
    Electronic Nicotine Delivery Systems*
    Aerosols/*toxicity
    Bronchi/*drug effects
    Epithelial Cells/*drug effects
    Tobacco Products/*toxicity
    Adenylate Kinase/metabolism ; Bronchi/metabolism ; Bronchi/pathology ; Cell Line ; Cell Survival/drug effects ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Humans ; Male ; Middle Aged ; Primary Cell Culture ; Proteome/metabolism ; Toxicity Tests ; Transcriptome/drug effects
    Czasopismo naukowe
    Szczegóły
    Podgląd okładki
    Tytuł :
    Assessment of the impact of aerosol from a potential modified risk tobacco product compared with cigarette smoke on human organotypic oral epithelial cultures under different exposure regimens.
    Autorzy :
    Zanetti F; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International Group of Companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland. Electronic address: .
    Sewer A; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International Group of Companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Scotti E; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International Group of Companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Titz B; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International Group of Companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Schlage WK; Biology Consultant, Max-Baermann-Str. 21, 51429 Bergisch Gladbach, Germany.
    Leroy P; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International Group of Companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Kondylis A; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International Group of Companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Vuillaume G; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International Group of Companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Iskandar AR; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International Group of Companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Guedj E; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International Group of Companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Trivedi K; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International Group of Companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Schneider T; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International Group of Companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Elamin A; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International Group of Companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Martin F; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International Group of Companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Frentzel S; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International Group of Companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Ivanov NV; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International Group of Companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Peitsch MC; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International Group of Companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Hoeng J; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International Group of Companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Pokaż więcej
    Źródło :
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2018 May; Vol. 115, pp. 148-169. Date of Electronic Publication: 2018 Mar 02.
    Typ publikacji :
    Journal Article
    MeSH Terms :
    Aerosols/*analysis
    Epithelial Cells/*drug effects
    Smoke/*adverse effects
    Tobacco/*chemistry
    Tobacco Products/*adverse effects
    Epithelial Cells/metabolism ; Humans ; Inhalation Exposure/adverse effects ; Inhalation Exposure/analysis ; MicroRNAs/genetics ; MicroRNAs/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Smoke/analysis ; Smoking/adverse effects ; Tobacco/adverse effects ; Tobacco Products/analysis
    Czasopismo naukowe
    Szczegóły
    Podgląd okładki
    Tytuł :
    Comparative biological impacts of an aerosol from carbon-heated tobacco and smoke from cigarettes on human respiratory epithelial cultures: A systems toxicology assessment.
    Autorzy :
    Iskandar AR; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International group of companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland. Electronic address: .
    Martin F; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International group of companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Leroy P; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International group of companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Schlage WK; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International group of companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Mathis C; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International group of companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Titz B; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International group of companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Kondylis A; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International group of companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Schneider T; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International group of companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Vuillaume G; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International group of companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Sewer A; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International group of companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Guedj E; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International group of companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Trivedi K; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International group of companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Elamin A; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International group of companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Frentzel S; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International group of companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Ivanov NV; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International group of companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Peitsch MC; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International group of companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Hoeng J; PMI R&D, Philip Morris Products S.A., Part of Philip Morris International group of companies, Quai Jeanrenaud 5, CH-2000 Neuchâtel, Switzerland.
    Pokaż więcej
    Źródło :
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2018 May; Vol. 115, pp. 109-126. Date of Electronic Publication: 2018 Mar 01.
    Typ publikacji :
    Comparative Study; Journal Article
    MeSH Terms :
    Aerosols/*toxicity
    Carbon/*chemistry
    Epithelial Cells/*drug effects
    Smoke/*adverse effects
    Tobacco/*toxicity
    Tobacco Products/*toxicity
    Aerosols/analysis ; Carbon/toxicity ; Cell Survival/drug effects ; Cytochrome P-450 Enzyme System/genetics ; Cytochrome P-450 Enzyme System/metabolism ; Epithelial Cells/cytology ; Humans ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Tobacco/chemistry ; Tobacco Products/analysis
    Czasopismo naukowe
    Szczegóły
    Podgląd okładki
    Tytuł :
    Biological changes in C57BL/6 mice following 3 weeks of inhalation exposure to cigarette smoke or e-vapor aerosols.
    Autorzy :
    Lee, K. Monica
    Hoeng, Julia
    Harbo, Sam
    Kogel, Ulrike
    Gardner, William
    Oldham, Michael
    Benson, Eric
    Talikka, Marja
    Kondylis, Athanasios
    Martin, Florian
    Titz, Bjoern
    Ansari, Sam
    Trivedi, Keyur
    Guedj, Emmanuel
    Elamin, Ashraf
    Ivanov, Nikolai V.
    Vanscheeuwijck, Patrick
    Peitsch, Manuel C.
    McKinney, Willie J.
    Pokaż więcej
    Temat :
    SMOKE
    CIGARETTE smoke
    MICROBIOLOGICAL aerosols
    AEROSOLS
    PROTEOMICS
    RESPIRATORY diseases
    GENE regulatory networks
    Źródło :
    Inhalation Toxicology; Nov/Dec2018, Vol. 30 Issue 13/14, p553-567, 15p
    Czasopismo naukowe
    Szczegóły Pełny tekst Pełny tekst
    Podgląd okładki
    Tytuł :
    Comparison of the biological impact of aerosol of e-vapor device with MESH® technology and cigarette smoke on human bronchial and alveolar cultures.
    Autorzy :
    Giralt, Albert (AUTHOR)
    Iskandar, Anita R (AUTHOR)
    Martin, Florian (AUTHOR)
    Moschini, Elisa (AUTHOR)
    Serchi, Tomasso (AUTHOR)
    Kondylis, Athanasios (AUTHOR)
    Marescotti, Diego (AUTHOR)
    Leroy, Patrice (AUTHOR)
    Ortega-Torres, Laura (AUTHOR)
    Majeed, Shoaib (AUTHOR)
    Merg, Celine (AUTHOR)
    Trivedi, Keyur (AUTHOR)
    Guedj, Emmanuel (AUTHOR)
    Frentzel, Stefan (AUTHOR)
    Ivanov, Nikolai V. (AUTHOR)
    Peitsch, Manuel C (AUTHOR)
    Gutleb, Arno C (AUTHOR)
    Hoeng, Julia (AUTHOR)
    Pokaż więcej
    Źródło :
    Toxicology Letters. Feb2021, Vol. 337, p98-110. 13p.
    Czasopismo naukowe
    Szczegóły
    Podgląd okładki
    Tytuł :
    Ceramide ratios are affected by cigarette smoke but not heat-not-burn or e-vapor aerosols across four independent mouse studies.
    Autorzy :
    Lavrynenko, Oksana (AUTHOR)
    Titz, Bjoern (AUTHOR)
    Dijon, Sophie (AUTHOR)
    Santos, Daniel Dos (AUTHOR)
    Nury, Catherine (AUTHOR)
    Schneider, Thomas (AUTHOR)
    Guedj, Emmanuel (AUTHOR)
    Szostak, Justyna (AUTHOR)
    Kondylis, Athanasios (AUTHOR)
    Phillips, Blaine (AUTHOR)
    Ekroos, Kim (AUTHOR)
    Martin, Florian (AUTHOR)
    Peitsch, Manuel C. (AUTHOR)
    Hoeng, Julia (AUTHOR)
    Ivanov, Nikolai V. (AUTHOR)
    Pokaż więcej
    Źródło :
    Life Sciences. Dec2020, Vol. 263, pN.PAG-N.PAG. 1p.
    Czasopismo naukowe
    Szczegóły
    Podgląd okładki
    Tytuł :
    Assessment of the impact of aerosol from a potential modified risk tobacco product compared with cigarette smoke on human organotypic oral epithelial cultures under different exposure regimens.
    Autorzy :
    Zanetti, Filippo
    Sewer, Alain
    Scotti, Elena
    Titz, Bjoern
    Schlage, Walter K.
    Leroy, Patrice
    Kondylis, Athanasios
    Vuillaume, Gregory
    Iskandar, Anita R.
    Guedj, Emmanuel
    Trivedi, Keyur
    Schneider, Thomas
    Elamin, Ashraf
    Martin, Florian
    Frentzel, Stefan
    Ivanov, Nikolai V.
    Peitsch, Manuel C.
    Hoeng, Julia
    Pokaż więcej
    Źródło :
    Food & Chemical Toxicology. May2018, Vol. 115, p148-169. 22p.
    Czasopismo naukowe
    Szczegóły
    Podgląd okładki
    Tytuł :
    Comparative biological impacts of an aerosol from carbon-heated tobacco and smoke from cigarettes on human respiratory epithelial cultures: A systems toxicology assessment.
    Autorzy :
    Iskandar, Anita R.
    Martin, Florian
    Leroy, Patrice
    Schlage, Walter K.
    Mathis, Carole
    Titz, Bjorn
    Kondylis, Athanasios
    Schneider, Thomas
    Vuillaume, Grégory
    Sewer, Alain
    Guedj, Emmanuel
    Trivedi, Keyur
    Elamin, Ashraf
    Frentzel, Stefan
    Ivanov, Nikolai V.
    Peitsch, Manuel C.
    Hoeng, Julia
    Pokaż więcej
    Źródło :
    Food & Chemical Toxicology. May2018, Vol. 115, p109-126. 18p.
    Czasopismo naukowe
    Szczegóły
      Wyświetlanie 1-12 z 12

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