- Tytuł:
-
Preclinical Development of Ipilimumab and Nivolumab Combination
Immunotherapy : Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology. - Autorzy:
- Źródło:
- PloS one [PLoS One] 2016 Sep 09; Vol. 11 (9), pp. e0161779. Date of Electronic Publication: 2016 Sep 09 (Print Publication: 2016).
- Typ publikacji:
- Journal Article
- MeSH Terms:
-
Immunotherapy *
Antibodies, Monoclonal/*therapeutic use
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Melanoma/*drug therapy
Animals ; Antibodies, Monoclonal/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; CTLA-4 Antigen/antagonists & inhibitors ; CTLA-4 Antigen/metabolism ; Cell Line, Tumor ; Cells, Cultured ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/therapy ; Combined Modality Therapy ; Disease Models, Animal ; Female ; Humans ; Ipilimumab ; Lymphocytes/immunology ; Lymphocytes/metabolism ; Macaca fascicularis ; Melanoma/metabolism ; Melanoma/therapy ; Mice ; Mice, Inbred C57BL ; Nivolumab ; Programmed Cell Death 1 Receptor/antagonists & inhibitors ; Programmed Cell Death 1 Receptor/metabolism ; T-Lymphocytes, Regulatory/metabolism
Czasopismo naukowe