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Wyświetlanie 1-10 z 10
Tytuł:
Systematically assessing microbiome-disease associations identifies drivers of inconsistency in metagenomic research.
Autorzy:
Tierney BT; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America.; Section on Pathophysiology and Molecular Pharmacology, Joslin Diabetes Center, Boston, Massachusetts, United States of America.; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, Massachusetts, United States of America.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America.
Tan Y; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America.
Yang Z; Section on Pathophysiology and Molecular Pharmacology, Joslin Diabetes Center, Boston, Massachusetts, United States of America.; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, Massachusetts, United States of America.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America.
Shui B; Department of Cancer Biology, Dana Farber Cancer Institute, Boston, Massachusetts, United States of America.
Walker MJ; UPSIDE Foods, Berkeley, California, United States of America.
Kent BM; US Marine Corps, Camp Pendleton, California, United States of America.
Kostic AD; Section on Pathophysiology and Molecular Pharmacology, Joslin Diabetes Center, Boston, Massachusetts, United States of America.; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, Massachusetts, United States of America.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America.
Patel CJ; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America.
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Źródło:
PLoS biology [PLoS Biol] 2022 Mar 02; Vol. 20 (3), pp. e3001556. Date of Electronic Publication: 2022 Mar 02 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Bacteria/*genetics
Biomedical Research/*methods
Gastrointestinal Microbiome/*genetics
Metagenome/*genetics
Metagenomics/*methods
Algorithms ; Bacteria/classification ; Cardiovascular Diseases/metabolism ; Cardiovascular Diseases/microbiology ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/microbiology ; Diabetes Mellitus, Type 1/metabolism ; Diabetes Mellitus, Type 1/microbiology ; Diabetes Mellitus, Type 2/metabolism ; Diabetes Mellitus, Type 2/microbiology ; Feces/microbiology ; Humans ; Inflammatory Bowel Diseases/metabolism ; Inflammatory Bowel Diseases/microbiology ; Liver Cirrhosis/metabolism ; Liver Cirrhosis/microbiology ; Models, Theoretical ; RNA, Ribosomal, 16S/genetics
Czasopismo naukowe
Tytuł:
Leveraging vibration of effects analysis for robust discovery in observational biomedical data science.
Autorzy:
Tierney BT; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America.; Section on Pathophysiology and Molecular Pharmacology, Joslin Diabetes Center, Boston, Massachusetts, United States of America.; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, Massachusetts, United States of America.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America.
Anderson E; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America.
Tan Y; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America.
Claypool K; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America.
Tangirala S; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Statistics and Data Science, Cornell University, Ithaca, New York, United States of America.
Kostic AD; Section on Pathophysiology and Molecular Pharmacology, Joslin Diabetes Center, Boston, Massachusetts, United States of America.; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, Massachusetts, United States of America.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America.
Manrai AK; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America.; Computational Health Informatics Program, Boston Children's Hospital, Boston, Massachusetts, United States of America.
Patel CJ; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America.
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Źródło:
PLoS biology [PLoS Biol] 2021 Sep 23; Vol. 19 (9), pp. e3001398. Date of Electronic Publication: 2021 Sep 23 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Models, Statistical*
Data Science/*methods
Observational Studies as Topic/*statistics & numerical data
Epidemiologic Methods ; Humans
Czasopismo naukowe
Tytuł:
Circulating short and medium chain fatty acids are associated with normoalbuminuria in type 1 diabetes of long duration.
Autorzy:
Moon S; Research Division, Joslin Diabetes Center, One Joslin Place, Boston, MA, 02215, USA.
Tsay JJ; Research Division, Joslin Diabetes Center, One Joslin Place, Boston, MA, 02215, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Medicine, Veterans Affairs Boston Healthcare System, Boston, MA, USA.
Lampert H; Research Division, Joslin Diabetes Center, One Joslin Place, Boston, MA, 02215, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Department of Family Medicine, Brown University, Providence, RI, USA.
Md Dom ZI; Research Division, Joslin Diabetes Center, One Joslin Place, Boston, MA, 02215, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Kostic AD; Research Division, Joslin Diabetes Center, One Joslin Place, Boston, MA, 02215, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Department of Microbiology, Harvard Medical School, Boston, MA, USA.
Smiles A; Research Division, Joslin Diabetes Center, One Joslin Place, Boston, MA, 02215, USA.
Niewczas MA; Research Division, Joslin Diabetes Center, One Joslin Place, Boston, MA, 02215, USA. .; Department of Medicine, Harvard Medical School, Boston, MA, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Apr 21; Vol. 11 (1), pp. 8592. Date of Electronic Publication: 2021 Apr 21.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Albuminuria/*etiology
Diabetes Mellitus, Type 1/*complications
Fatty Acids/*blood
Fatty Acids, Volatile/*blood
Adult ; Albuminuria/blood ; Biomarkers/blood ; Diabetes Mellitus, Type 1/blood ; Female ; Humans ; Male ; Metabolomics ; Multivariate Analysis ; Risk Factors ; Time Factors
Czasopismo naukowe
Tytuł:
A systematic machine learning and data type comparison yields metagenomic predictors of infant age, sex, breastfeeding, antibiotic usage, country of origin, and delivery type.
Autorzy:
Le Goallec A; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Systems Biology, Harvard University, Cambridge, Massachusetts, United States of America.
Tierney BT; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America.; Section on Pathophysiology and Molecular Pharmacology, Joslin Diabetes Center, Boston, Massachusetts, United States of America.; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, Massachusetts, United States of America.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America.
Luber JM; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America.
Cofer EM; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America.
Kostic AD; Section on Pathophysiology and Molecular Pharmacology, Joslin Diabetes Center, Boston, Massachusetts, United States of America.; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, Massachusetts, United States of America.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America.
Patel CJ; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2020 May 11; Vol. 16 (5), pp. e1007895. Date of Electronic Publication: 2020 May 11 (Print Publication: 2020).
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Breast Feeding*
Machine Learning*
Metagenomics*
Anti-Bacterial Agents/*administration & dosage
Algorithms ; Female ; Geography ; Humans ; Infant ; Male ; Models, Theoretical
Czasopismo naukowe
Tytuł:
Assessment of the cPAS-based BGISEQ-500 platform for metagenomic sequencing.
Autorzy:
Fang C; BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.; China National GeneBank, BGI-Shenzhen, Dapeng New District, Shenzhen 518120, China.; Shenzhen Key Laboratory of Human Commensal Microorganisms and Health Research, BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.
Zhong H; BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.; China National GeneBank, BGI-Shenzhen, Dapeng New District, Shenzhen 518120, China.; Laboratory of Genomics and Molecular Biomedicine, Department of Biology, University of Copenhagen, Copenhagen Biocenter, Ole Maaløes Vej 5, DK-2200 Copenhagen N, Denmark.
Lin Y; BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.; China National GeneBank, BGI-Shenzhen, Dapeng New District, Shenzhen 518120, China.; Shenzhen Key Laboratory of Human Commensal Microorganisms and Health Research, BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.
Chen B; BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.; China National GeneBank, BGI-Shenzhen, Dapeng New District, Shenzhen 518120, China.; Shenzhen Key Laboratory of Human Commensal Microorganisms and Health Research, BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.
Han M; BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.; China National GeneBank, BGI-Shenzhen, Dapeng New District, Shenzhen 518120, China.; Shenzhen Key Laboratory of Human Commensal Microorganisms and Health Research, BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.
Ren H; BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.; China National GeneBank, BGI-Shenzhen, Dapeng New District, Shenzhen 518120, China.; Shenzhen Key Laboratory of Human Commensal Microorganisms and Health Research, BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.
Lu H; BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.; China National GeneBank, BGI-Shenzhen, Dapeng New District, Shenzhen 518120, China.
Luber JM; Program in Bioinformatics and Integrative Genomics, Division of Medical Sciences, Harvard Medical School, BIG Program Office, 10 Shattuck Street, Countway Library, 4th Floor, Boston, MA 02115, USA.; Graduate School of Arts and Sciences, Harvard University, Richard A. and Susan F. Smith Campus Center, 1350 Massachusetts Avenue, Suite 350, Cambridge, MA 02138-3654, USA.; Section on Pathophysiology and Molecular Pharmacology, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA.; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA.; Department of Biomedical Informatics, Harvard Medical School, 10 Shattuck Street, 4th Floor, Boston, MA 02115, USA.
Xia M; BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.; China National GeneBank, BGI-Shenzhen, Dapeng New District, Shenzhen 518120, China.
Li W; BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.; China National GeneBank, BGI-Shenzhen, Dapeng New District, Shenzhen 518120, China.
Stein S; Graduate School of Arts and Sciences, Harvard University, Richard A. and Susan F. Smith Campus Center, 1350 Massachusetts Avenue, Suite 350, Cambridge, MA 02138-3654, USA.; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, 450 Brookline Ave., Boston, MA 02215-5450, USA.; Department of Biostatistics, Harvard TH Chan School of Public Health, 655 Huntington Avenue, Building 2, 4th Floor, Boston, MA 02115, USA.
Xu X; BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.; China National GeneBank, BGI-Shenzhen, Dapeng New District, Shenzhen 518120, China.
Zhang W; BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.
Drmanac R; BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.
Wang J; BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.; James D. Watson Institute of Genome Sciences, No.51, Zhijiang Road, Xihu District, Hangzhou, Zhejiang Province, 310058, P. R. China.
Yang H; BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.; James D. Watson Institute of Genome Sciences, No.51, Zhijiang Road, Xihu District, Hangzhou, Zhejiang Province, 310058, P. R. China.
Hammarström L; Division of Clinical Immunology and Transfusion Medicine, Department of Laboratory Medicine, Clinical University Hospital, Huddinge, SE-14186 Stockholm, Sweden.
Kostic AD; Section on Pathophysiology and Molecular Pharmacology, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA.; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA.; Department of Biomedical Informatics, Harvard Medical School, 10 Shattuck Street, 4th Floor, Boston, MA 02115, USA.
Kristiansen K; BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.; China National GeneBank, BGI-Shenzhen, Dapeng New District, Shenzhen 518120, China.; Laboratory of Genomics and Molecular Biomedicine, Department of Biology, University of Copenhagen, Copenhagen Biocenter, Ole Maaløes Vej 5, DK-2200 Copenhagen N, Denmark.
Li J; BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.; China National GeneBank, BGI-Shenzhen, Dapeng New District, Shenzhen 518120, China.; Shenzhen Key Laboratory of Human Commensal Microorganisms and Health Research, BGI-Shenzhen, Building 11, Beishan Industrial Zone, Yantian, Shenzhen 518083, China.; School of Bioscience and Biotechnology, South China University of Technology, No.381 Wushan Road, Tianhe District, Guangzhou, Guangdong 510630, China.
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Źródło:
GigaScience [Gigascience] 2018 Mar 01; Vol. 7 (3), pp. 1-8.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Bacteria/*genetics
Gastrointestinal Microbiome/*genetics
Metagenomics/*methods
Sequence Analysis, DNA/*methods
Bacteria/classification ; Computational Biology ; Feces/microbiology ; High-Throughput Nucleotide Sequencing/methods ; Humans
Czasopismo naukowe
Tytuł:
Dysbiosis, inflammation, and response to treatment: a longitudinal study of pediatric subjects with newly diagnosed inflammatory bowel disease.
Autorzy:
Shaw KA; Graduate Program in Genetics and Molecular Biology, Graduate Division of Biological and Biomedical Sciences, Emory University, Atlanta, GA, 30322, USA.
Bertha M; Department of Pediatrics, Emory University School of Medicine & Children's Healthcare of Atlanta, 2015 Uppergate Drive, room 248, Atlanta, GA, 30322, USA.
Hofmekler T; Department of Pediatrics, Emory University School of Medicine & Children's Healthcare of Atlanta, 2015 Uppergate Drive, room 248, Atlanta, GA, 30322, USA.
Chopra P; Department of Pediatrics, Emory University School of Medicine & Children's Healthcare of Atlanta, 2015 Uppergate Drive, room 248, Atlanta, GA, 30322, USA.
Vatanen T; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Department of Computer Science, Aalto University School of Science, 02150, Espoo, Finland.
Srivatsa A; Department of Pediatrics, Emory University School of Medicine & Children's Healthcare of Atlanta, 2015 Uppergate Drive, room 248, Atlanta, GA, 30322, USA.
Prince J; Department of Pediatrics, Emory University School of Medicine & Children's Healthcare of Atlanta, 2015 Uppergate Drive, room 248, Atlanta, GA, 30322, USA.
Kumar A; Department of Pediatrics, Emory University School of Medicine & Children's Healthcare of Atlanta, 2015 Uppergate Drive, room 248, Atlanta, GA, 30322, USA.
Sauer C; Department of Pediatrics, Emory University School of Medicine & Children's Healthcare of Atlanta, 2015 Uppergate Drive, room 248, Atlanta, GA, 30322, USA.
Zwick ME; Department of Human Genetics, Emory University, Atlanta, GA, 30322, USA.
Satten GA; Centers for Disease Control and Prevention, Atlanta, GA, 30341, USA.
Kostic AD; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.
Mulle JG; Department of Human Genetics, Emory University, Atlanta, GA, 30322, USA.; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, 30322, USA.
Xavier RJ; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.
Kugathasan S; Department of Pediatrics, Emory University School of Medicine & Children's Healthcare of Atlanta, 2015 Uppergate Drive, room 248, Atlanta, GA, 30322, USA. .; Department of Human Genetics, Emory University, Atlanta, GA, 30322, USA. .
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Źródło:
Genome medicine [Genome Med] 2016 Jul 13; Vol. 8 (1), pp. 75. Date of Electronic Publication: 2016 Jul 13.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Bacteria/*classification
Colitis, Ulcerative/*drug therapy
Crohn Disease/*drug therapy
Dysbiosis/*drug therapy
Immunologic Factors/*therapeutic use
Intestinal Mucosa/*drug effects
Adolescent ; Bacteria/genetics ; Bacteria/isolation & purification ; Biomarkers/metabolism ; Case-Control Studies ; Child ; Child, Preschool ; Colitis, Ulcerative/diagnosis ; Colitis, Ulcerative/immunology ; Colitis, Ulcerative/microbiology ; Crohn Disease/diagnosis ; Crohn Disease/immunology ; Crohn Disease/microbiology ; Dysbiosis/diagnosis ; Dysbiosis/immunology ; Dysbiosis/microbiology ; Feces/chemistry ; Feces/microbiology ; Female ; Gastrointestinal Microbiome/drug effects ; Gastrointestinal Microbiome/genetics ; Gastrointestinal Tract/drug effects ; Gastrointestinal Tract/immunology ; Gastrointestinal Tract/microbiology ; Humans ; Inflammation ; Intestinal Mucosa/immunology ; Intestinal Mucosa/microbiology ; Leukocyte L1 Antigen Complex/metabolism ; Longitudinal Studies ; Male ; Severity of Illness Index ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response.
Autorzy:
Pulloor NK; Program on Emerging Infectious Diseases, DUKE-NUS Graduate Medical School, Singapore.
Nair S; Program on Emerging Infectious Diseases, DUKE-NUS Graduate Medical School, Singapore.
McCaffrey K
Kostic AD; Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
Bist P; Program on Emerging Infectious Diseases, DUKE-NUS Graduate Medical School, Singapore.
Weaver JD; Inositol Signaling Group, Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, North Carolina, United States of America.
Riley AM; Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath, United Kingdom.
Tyagi R; Solomon H. Snyder Department of Neuroscience and Departments of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Uchil PD; Section of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut, United States of America.
York JD; Department of Biochemistry, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.
Snyder SH; Solomon H. Snyder Department of Neuroscience and Departments of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
García-Sastre A; Department of Microbiology, Global Health and Emerging Pathogens Institute, Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Potter BV; Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath, United Kingdom.
Lin R; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.
Shears SB; Inositol Signaling Group, Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, North Carolina, United States of America.
Xavier RJ; Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
Krishnan MN; Program on Emerging Infectious Diseases, DUKE-NUS Graduate Medical School, Singapore.
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Źródło:
PLoS pathogens [PLoS Pathog] 2014 Feb 27; Vol. 10 (2), pp. e1003981. Date of Electronic Publication: 2014 Feb 27 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation/*immunology
Interferon Type I/*immunology
Phosphoric Monoester Hydrolases/*immunology
Receptors, Retinoic Acid/*immunology
Signal Transduction/*immunology
Humans ; Immunity, Innate/immunology ; Interferon Regulatory Factor-3/immunology ; RNA, Small Interfering
Czasopismo naukowe
Tytuł:
The TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasis.
Autorzy:
Sealey DC; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
Kostic AD
LeBel C
Pryde F
Harrington L
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Źródło:
BMC molecular biology [BMC Mol Biol] 2011 Oct 18; Vol. 12, pp. 45. Date of Electronic Publication: 2011 Oct 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*chemistry
Saccharomyces cerevisiae Proteins/*metabolism
Telomerase/*chemistry
Telomerase/*metabolism
Telomere/*metabolism
Humans ; Protein Binding ; Protein Structure, Tertiary ; Saccharomyces cerevisiae/chemistry ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/genetics ; Species Specificity ; Telomerase/genetics ; Telomere/genetics
Czasopismo naukowe
Tytuł:
PathSeq: software to identify or discover microbes by deep sequencing of human tissue.
Autorzy:
Kostic AD
Ojesina AI
Pedamallu CS
Jung J
Verhaak RG
Getz G
Meyerson M
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Źródło:
Nature biotechnology [Nat Biotechnol] 2011 May; Vol. 29 (5), pp. 393-6.
Typ publikacji:
Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Genome, Human*
Software*
High-Throughput Nucleotide Sequencing/*methods
Sequence Analysis, RNA/*methods
Computational Biology ; Databases, Nucleic Acid ; Gene Library ; Genome, Viral ; HeLa Cells ; Human papillomavirus 18/isolation & purification ; Humans
Raport
    Wyświetlanie 1-10 z 10

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