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Wyświetlanie 1-20 z 27
Tytuł:
Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity.
Autorzy:
Kimani SG; Rutgers University, New Jersey Medical School, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, 205 South Orange Ave, Newark, NJ 07103, USA.
Kumar S; Rutgers University, New Jersey Medical School, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, 205 South Orange Ave, Newark, NJ 07103, USA.
Bansal N; Rutgers University, Cancer Institute of New Jersey, 195 Little Albany Street, New Brunswick, NJ 08903, USA.
Singh K; Department of Molecular Microbiology and Immunology, and Department of Biochemistry, Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA.
Kholodovych V; Rutgers University, Office of Advanced Research Computing, 96 Frelinghuysen Road, Piscataway, NJ 08854, USA.; Rutgers University, Robert Wood Johnson Medical Center, Department of Pharmacology, 675 Hoes Lane, Piscataway, NJ 08854, USA.
Comollo T; Rutgers University, New Jersey Medical School, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, 205 South Orange Ave, Newark, NJ 07103, USA.
Peng Y; Rutgers University, Cancer Institute of New Jersey, 195 Little Albany Street, New Brunswick, NJ 08903, USA.
Kotenko SV; Rutgers University, New Jersey Medical School, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, 205 South Orange Ave, Newark, NJ 07103, USA.
Sarafianos SG; Department of Molecular Microbiology and Immunology, and Department of Biochemistry, Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA.
Bertino JR; Rutgers University, Cancer Institute of New Jersey, 195 Little Albany Street, New Brunswick, NJ 08903, USA.
Welsh WJ; Rutgers University, Cancer Institute of New Jersey, 195 Little Albany Street, New Brunswick, NJ 08903, USA.; Rutgers University, Robert Wood Johnson Medical Center, Department of Pharmacology, 675 Hoes Lane, Piscataway, NJ 08854, USA.
Birge RB; Rutgers University, New Jersey Medical School, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, 205 South Orange Ave, Newark, NJ 07103, USA.
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Źródło:
Scientific reports [Sci Rep] 2017 Mar 08; Vol. 7, pp. 43908. Date of Electronic Publication: 2017 Mar 08.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinogenesis/*drug effects
Intercellular Signaling Peptides and Proteins/*metabolism
Isoxazoles/*pharmacology
Piperazines/*pharmacology
Protein Kinase Inhibitors/*metabolism
Proto-Oncogene Proteins/*metabolism
Receptor Protein-Tyrosine Kinases/*metabolism
c-Mer Tyrosine Kinase/*metabolism
Animals ; Binding Sites ; Body Weight/drug effects ; Cell Line, Tumor ; Humans ; Intercellular Signaling Peptides and Proteins/chemistry ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Neoplasms/drug therapy ; Neoplasms/metabolism ; Neoplasms/pathology ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Proto-Oncogene Proteins/chemistry ; Receptor Protein-Tyrosine Kinases/chemistry ; Transplantation, Heterologous ; c-Mer Tyrosine Kinase/chemistry ; Axl Receptor Tyrosine Kinase
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase.
Autorzy:
Kimani SG; Rutgers, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, Rutgers- New Jersey Medical School, 205 South Orange Ave, Newark, NJ, 07103, USA.
Kumar S; Rutgers, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, Rutgers- New Jersey Medical School, 205 South Orange Ave, Newark, NJ, 07103, USA.
Davra V; Rutgers, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, Rutgers- New Jersey Medical School, 205 South Orange Ave, Newark, NJ, 07103, USA.
Chang YJ; Rutgers, Biomedical and Health Sciences, OIT/High Performance and Research Computing, 185 South Orange Ave, Newark, NJ, 07103, USA.
Kasikara C; Rutgers, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, Rutgers- New Jersey Medical School, 205 South Orange Ave, Newark, NJ, 07103, USA.
Geng K; Rutgers, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, Rutgers- New Jersey Medical School, 205 South Orange Ave, Newark, NJ, 07103, USA.
Tsou WI; Rutgers, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, Rutgers- New Jersey Medical School, 205 South Orange Ave, Newark, NJ, 07103, USA.
Wang S; Rutgers, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, Rutgers- New Jersey Medical School, 205 South Orange Ave, Newark, NJ, 07103, USA.
Hoque M; Rutgers, Department of Microbiology, Biochemistry and Molecular Genetics, Genomics Research Program, Rutgers- New Jersey Medical School, 185 South Orange Ave, Newark, NJ, 07103, USA.
Boháč A; Department of Organic Chemistry, Comenius University in Bratislava, Faculty of Natural Sciences, Mlynská dolina, Ilkovičova 6, 842 15, Bratislava, Slovakia.; Biomagi, Ltd, Mamateyova 26, 851 04, Bratislava, Slovakia.
Lewis-Antes A; Rutgers, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, Rutgers- New Jersey Medical School, 205 South Orange Ave, Newark, NJ, 07103, USA.
De Lorenzo MS; Rutgers, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, Rutgers- New Jersey Medical School, 205 South Orange Ave, Newark, NJ, 07103, USA.
Kotenko SV; Rutgers, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, Rutgers- New Jersey Medical School, 205 South Orange Ave, Newark, NJ, 07103, USA.
Birge RB; Rutgers, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, Rutgers- New Jersey Medical School, 205 South Orange Ave, Newark, NJ, 07103, USA. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2016 Sep 06; Vol. 14 (1), pp. 19. Date of Electronic Publication: 2016 Sep 06.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Signal Transduction*
ErbB Receptors/*metabolism
Mammary Neoplasms, Experimental/*metabolism
Proto-Oncogene Proteins/*metabolism
Receptor Protein-Tyrosine Kinases/*metabolism
Animals ; CHO Cells ; Cell Movement ; Cricetinae ; Cricetulus ; ErbB Receptors/genetics ; Female ; Humans ; Mammary Neoplasms, Experimental/pathology ; Mice ; Mice, Inbred BALB C ; Proto-Oncogene Proteins/genetics ; Receptor Protein-Tyrosine Kinases/genetics ; c-Mer Tyrosine Kinase ; Axl Receptor Tyrosine Kinase
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Correction: Distinct Roles of Type I and Type III Interferons in Intestinal Immunity to Homologous and Heterologous Rotavirus Infections.
Autorzy:
Lin JD
Feng N
Sen A
Balan M
Tseng HC
McElrath C
Smirnov SV
Peng J
Yasukawa LL
Durbin RK
Durbin JE
Greenberg HB
Kotenko SV
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Źródło:
PLoS pathogens [PLoS Pathog] 2016 Jun 15; Vol. 12 (6), pp. e1005726. Date of Electronic Publication: 2016 Jun 15 (Print Publication: 2016).
Typ publikacji:
Journal Article; Published Erratum
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Distinct Roles of Type I and Type III Interferons in Intestinal Immunity to Homologous and Heterologous Rotavirus Infections.
Autorzy:
Lin JD; Department of Microbiology, Biochemistry and Molecular Genetics, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Rutgers, Newark, New Jersey, United States of America.; Department of Pathology and Laboratory Medicine, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Rutgers, Newark, New Jersey, United States of America.
Feng N; Stanford University, Stanford, California, United States of America.; VA Palo Alto Health Care System, Palo Alto, California, United States of America.
Sen A; Stanford University, Stanford, California, United States of America.; VA Palo Alto Health Care System, Palo Alto, California, United States of America.
Balan M; Department of Microbiology, Biochemistry and Molecular Genetics, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Rutgers, Newark, New Jersey, United States of America.
Tseng HC; Department of Pathology and Laboratory Medicine, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Rutgers, Newark, New Jersey, United States of America.
McElrath C; Department of Microbiology, Biochemistry and Molecular Genetics, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Rutgers, Newark, New Jersey, United States of America.
Smirnov SV; Department of Microbiology, Biochemistry and Molecular Genetics, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Rutgers, Newark, New Jersey, United States of America.
Peng J; Department of Microbiology, Biochemistry and Molecular Genetics, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Rutgers, Newark, New Jersey, United States of America.
Yasukawa LL; Stanford University, Stanford, California, United States of America.; VA Palo Alto Health Care System, Palo Alto, California, United States of America.
Durbin RK; Center for Immunity and Inflammation, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Rutgers, Newark, New Jersey, United States of America.
Durbin JE; Department of Pathology and Laboratory Medicine, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Rutgers, Newark, New Jersey, United States of America.; Center for Immunity and Inflammation, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Rutgers, Newark, New Jersey, United States of America.; University Hospital Cancer Center, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Rutgers, Newark, New Jersey, United States of America.
Greenberg HB; Stanford University, Stanford, California, United States of America.; VA Palo Alto Health Care System, Palo Alto, California, United States of America.
Kotenko SV; Department of Microbiology, Biochemistry and Molecular Genetics, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Rutgers, Newark, New Jersey, United States of America.; Center for Immunity and Inflammation, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Rutgers, Newark, New Jersey, United States of America.; University Hospital Cancer Center, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Rutgers, Newark, New Jersey, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2016 Apr 29; Vol. 12 (4), pp. e1005600. Date of Electronic Publication: 2016 Apr 29 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Interferon Type I/*immunology
Interferon-gamma/*immunology
Intestines/*immunology
Rotavirus Infections/*immunology
Animals ; Animals, Newborn ; Disease Models, Animal ; Enzyme-Linked Immunosorbent Assay ; Humans ; Immunoblotting ; Immunohistochemistry ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Polymerase Chain Reaction ; Rotavirus
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Critical role of the endogenous interferon ligand-receptors in type I and type II interferons response.
Autorzy:
Lasfar A; Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, NJ, USA; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
Cook JR
Cohen Solal KA
Reuhl K
Kotenko SV
Langer JA
Laskin DL
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Źródło:
Immunology [Immunology] 2014 Jul; Vol. 142 (3), pp. 442-52.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Interferon Type I/*immunology
Interferon Type I/*metabolism
Interferon-gamma/*immunology
Interferon-gamma/*metabolism
Receptor, Interferon alpha-beta/*metabolism
Animals ; Ligands ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Knockout ; Receptor, Interferon alpha-beta/deficiency ; Receptor, Interferon alpha-beta/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Interferon induction and function at the mucosal surface.
Autorzy:
Durbin RK; Department of Pathology, New York University School of Medicine, New York, NY 10016, USA.
Kotenko SV
Durbin JE
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Źródło:
Immunological reviews [Immunol Rev] 2013 Sep; Vol. 255 (1), pp. 25-39.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms:
Interferons/*immunology
Interferons/*metabolism
Mucous Membrane/*immunology
Mucous Membrane/*metabolism
Animals ; Gene Expression Regulation ; Humans ; Janus Kinases/metabolism ; Ligands ; Mucous Membrane/virology ; Phosphorylation ; Protein Biosynthesis ; STAT Transcription Factors/metabolism ; Signal Transduction ; Toll-Like Receptors/metabolism ; Virus Diseases/genetics ; Virus Diseases/immunology ; Virus Diseases/metabolism ; Viruses/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Regulation of apoptosis by type III interferons.
Autorzy:
Li W; Department of Biochemistry and Molecular Biology, New Jersey Medical School-University Hospital Cancer Center, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA.
Lewis-Antes A; Department of Biochemistry and Molecular Biology, New Jersey Medical School-University Hospital Cancer Center, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA.
Huang J; Department of Biochemistry and Molecular Biology, New Jersey Medical School-University Hospital Cancer Center, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA.
Balan M; Department of Biochemistry and Molecular Biology, New Jersey Medical School-University Hospital Cancer Center, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA.
Kotenko SV; Department of Biochemistry and Molecular Biology, New Jersey Medical School-University Hospital Cancer Center, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA.
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Źródło:
Cell proliferation [Cell Prolif] 2008 Dec; Vol. 41 (6), pp. 960-979.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Apoptosis/*drug effects
Interferons/*pharmacology
Caspases/metabolism ; Cell Cycle/drug effects ; Cell Line, Tumor ; DNA Fragmentation/drug effects ; Enzyme Activation/drug effects ; Humans ; Phosphatidylserines/metabolism ; Receptors, Interferon/metabolism ; STAT1 Transcription Factor/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 27

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