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Wyszukujesz frazę ""Krieg, Thomas"" wg kryterium: Autor


Tytuł :
Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo.
Autorzy :
Booty LM; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK.
Gawel JM; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK.
Cvetko F; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK.
Caldwell ST; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK.
Hall AR; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK.
Mulvey JF; Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK.
James AM; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK.
Hinchy EC; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK.
Prime TA; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK.
Arndt S; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK.
Beninca C; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK.
Bright TP; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK.
Clatworthy MR; Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK.
Ferdinand JR; Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK.
Prag HA; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK.
Logan A; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK.
Prudent J; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK.
Krieg T; Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK.
Hartley RC; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK. Electronic address: .
Murphy MP; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK; Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK. Electronic address: .
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Źródło :
Cell chemical biology [Cell Chem Biol] 2019 Mar 21; Vol. 26 (3), pp. 449-461.e8. Date of Electronic Publication: 2019 Jan 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mitochondria/*metabolism
Sulfhydryl Compounds/*chemistry
Animals ; Chromatography, High Pressure Liquid ; Dinitrochlorobenzene/analysis ; Dinitrochlorobenzene/chemistry ; Dinitrochlorobenzene/metabolism ; Dinitrochlorobenzene/pharmacology ; Glutathione/chemistry ; Glutathione/metabolism ; Glutathione Transferase/metabolism ; Hep G2 Cells ; Humans ; Liver/chemistry ; Liver/metabolism ; Membrane Potential, Mitochondrial/drug effects ; Mice ; Oxidation-Reduction ; Reactive Oxygen Species/chemistry ; Reactive Oxygen Species/metabolism ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/chemistry ; Recombinant Proteins/isolation & purification ; Tandem Mass Spectrometry ; Thioredoxins/antagonists & inhibitors ; Thioredoxins/genetics ; Thioredoxins/metabolism
Czasopismo naukowe
Tytuł :
Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly.
Autorzy :
Hinchy EC; From the MRC Mitochondrial Biology Unit, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY.
Gruszczyk AV; From the MRC Mitochondrial Biology Unit, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY.; the University Department of Surgery and Cambridge NIHR Biomedical Research Centre Addenbrooke's Hospital, Cambridge CB2 0QQ.
Willows R; the MRC London Institute of Medical Sciences, Hammersmith Hospital, Imperial College, London, W12 0NN, and.
Navaratnam N; the MRC London Institute of Medical Sciences, Hammersmith Hospital, Imperial College, London, W12 0NN, and.
Hall AR; From the MRC Mitochondrial Biology Unit, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY.
Bates G; From the MRC Mitochondrial Biology Unit, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY.
Bright TP; From the MRC Mitochondrial Biology Unit, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY.
Krieg T; the Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, United Kingdom.
Carling D; the MRC London Institute of Medical Sciences, Hammersmith Hospital, Imperial College, London, W12 0NN, and.
Murphy MP; From the MRC Mitochondrial Biology Unit, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2018 Nov 02; Vol. 293 (44), pp. 17208-17217. Date of Electronic Publication: 2018 Sep 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
AMP-Activated Protein Kinases/*metabolism
Mitochondria/*metabolism
Reactive Oxygen Species/*metabolism
AMP-Activated Protein Kinases/genetics ; Adenosine Diphosphate/metabolism ; Adenosine Triphosphate/metabolism ; Animals ; Cell Line ; Enzyme Activation ; Humans ; Hydrogen Peroxide/metabolism ; Mice ; Mitochondria/genetics ; Muscle Fibers, Skeletal/enzymology ; Muscle Fibers, Skeletal/metabolism ; Oxidation-Reduction
Czasopismo naukowe
Tytuł :
Monoamine oxidase-dependent endoplasmic reticulum-mitochondria dysfunction and mast cell degranulation lead to adverse cardiac remodeling in diabetes.
Autorzy :
Deshwal S; Department of Biomedical Sciences, University of Padova, 35131, Padova, Italy.; Institute for Genetics, University of Cologne, Cologne, 50931, Germany.
Forkink M; Department of Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK.
Hu CH; Department of Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK.
Buonincontri G; Department of Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK.
Antonucci S; Department of Biomedical Sciences, University of Padova, 35131, Padova, Italy.
Di Sante M; Neuroscience Institute, National Research Council of Italy (CNR), 35131, Padova, Italy.
Murphy MP; Mitochondrial Biology Unit, MRC, Cambridge, CB2 0XY, UK.
Paolocci N; Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, 21205, USA.; Department of Experimental Medicine, University of Perugia, 06123, Perugia, Italy.
Mochly-Rosen D; Department of Chemical and Systems Biology, School of Medicine, Stanford University, Stanford, CA, 94305-5174, USA.
Krieg T; Department of Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK.
Di Lisa F; Department of Biomedical Sciences, University of Padova, 35131, Padova, Italy. .; Neuroscience Institute, National Research Council of Italy (CNR), 35131, Padova, Italy. .
Kaludercic N; Neuroscience Institute, National Research Council of Italy (CNR), 35131, Padova, Italy. .
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Źródło :
Cell death and differentiation [Cell Death Differ] 2018 Sep; Vol. 25 (9), pp. 1671-1685. Date of Electronic Publication: 2018 Feb 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoplasmic Reticulum Stress*/drug effects
Cell Degranulation/*drug effects
Mitochondria/*metabolism
Monoamine Oxidase/*metabolism
Monoamine Oxidase Inhibitors/*pharmacology
Ventricular Remodeling/*drug effects
Animals ; Diabetes Mellitus, Experimental/chemically induced ; Diabetes Mellitus, Experimental/pathology ; Glucose/pharmacology ; Interleukin-1beta/pharmacology ; Male ; Mice ; Mice, Inbred C57BL ; Mitochondria/drug effects ; Mitochondrial Membrane Transport Proteins/metabolism ; Mitochondrial Permeability Transition Pore ; Monoamine Oxidase/chemistry ; Monoamine Oxidase/genetics ; Muscle Cells/cytology ; Muscle Cells/metabolism ; Muscle Cells/physiology ; Myocardium/metabolism ; Myocardium/pathology ; RNA Interference ; RNA, Small Interfering/metabolism ; Rats ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
MitoNeoD: A Mitochondria-Targeted Superoxide Probe.
Autorzy :
Shchepinova MM; WestCHEM School of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK.
Cairns AG; WestCHEM School of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK.
Prime TA; MRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.
Logan A; MRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.
James AM; MRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.
Hall AR; MRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.
Vidoni S; MRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.
Arndt S; MRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.
Caldwell ST; WestCHEM School of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK.
Prag HA; MRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.
Pell VR; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.
Krieg T; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.
Mulvey JF; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.
Yadav P; School of Chemical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Cobley JN; Division of Sport and Exercise Sciences, Abertay University, Dundee DD1 1HG, UK.
Bright TP; MRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.
Senn HM; WestCHEM School of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK.
Anderson RF; School of Chemical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Murphy MP; MRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK. Electronic address: .
Hartley RC; WestCHEM School of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK. Electronic address: .
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Źródło :
Cell chemical biology [Cell Chem Biol] 2017 Oct 19; Vol. 24 (10), pp. 1285-1298.e12. Date of Electronic Publication: 2017 Sep 07.
Typ publikacji :
Journal Article
MeSH Terms :
Mitochondria/*metabolism
Molecular Probes/*metabolism
Superoxides/*metabolism
Animals ; Biological Transport ; Cell Line ; DNA/chemistry ; DNA/metabolism ; Male ; Mass Spectrometry ; Mice ; Models, Molecular ; Molecular Probes/chemistry ; Nucleic Acid Conformation ; Oxidation-Reduction
Czasopismo naukowe
Tytuł :
Assessment of H 2 S in vivo using the newly developed mitochondria-targeted mass spectrometry probe MitoA.
Autorzy :
Arndt S; From the MRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, United Kingdom.
Baeza-Garza CD; the WestCHEM School of Chemistry, University of Glasgow, Glasgow G12 8QQ, United Kingdom.
Logan A; From the MRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, United Kingdom.
Rosa T; the Department of Medicine, University of Cambridge, Biomedical Campus, Cambridge, CB2 2QQ, United Kingdom.
Wedmann R; the Department of Chemistry and Pharmacy, Friedrich-Alexander University of Erlangen-Nuremberg, Egerlandstrasse,1, 91058 Erlangen, Germany.
Prime TA; From the MRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, United Kingdom.
Martin JL; the Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge CB2 2QQ, United Kingdom.
Saeb-Parsy K; the Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge CB2 2QQ, United Kingdom.
Krieg T; the Department of Medicine, University of Cambridge, Biomedical Campus, Cambridge, CB2 2QQ, United Kingdom.
Filipovic MR; the Department of Chemistry and Pharmacy, Friedrich-Alexander University of Erlangen-Nuremberg, Egerlandstrasse,1, 91058 Erlangen, Germany.; the University of Bordeaux, IBGC, UMR 5095, F-33077 Bordeaux, France, and.
Hartley RC; the WestCHEM School of Chemistry, University of Glasgow, Glasgow G12 8QQ, United Kingdom, .
Murphy MP; From the MRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, United Kingdom, .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2017 May 12; Vol. 292 (19), pp. 7761-7773. Date of Electronic Publication: 2017 Mar 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hydrogen Sulfide/*chemistry
Mass Spectrometry/*methods
Mitochondria/*metabolism
Animals ; Cations ; Cell Line ; Chromatography, High Pressure Liquid ; Chromatography, Liquid ; Female ; HCT116 Cells ; Heterocyclic Compounds/chemistry ; Humans ; Hypoxia ; Liver/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Myocardial Ischemia/metabolism ; Organophosphorus Compounds/chemistry ; Rats, Wistar ; Tandem Mass Spectrometry ; Temperature ; Ultraviolet Rays
Czasopismo naukowe
Tytuł :
A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury.
Autorzy :
Chouchani ET; Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
Pell VR; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, UK.
James AM; MRC Mitochondrial Biology Unit, Hills Road, Cambridge CB2 0XY, UK.
Work LM; Institute of Cardiovascular & Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8TA, UK.
Saeb-Parsy K; University Department of Surgery and Cambridge NIHR Biomedical Research Centre, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.
Frezza C; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Box 197, Cambridge Biomedical Campus, Cambridge, CB2 0XZ, UK.
Krieg T; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, UK.
Murphy MP; MRC Mitochondrial Biology Unit, Hills Road, Cambridge CB2 0XY, UK. Electronic address: .
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Źródło :
Cell metabolism [Cell Metab] 2016 Feb 09; Vol. 23 (2), pp. 254-63. Date of Electronic Publication: 2016 Jan 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Mitochondria/*metabolism
Reperfusion Injury/*metabolism
Superoxides/*metabolism
Animals ; Electron Transport ; Humans ; Models, Biological ; Sulfhydryl Compounds/metabolism
Czasopismo naukowe
Tytuł :
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
Autorzy :
Chouchani ET; MRC Mitochondrial Biology Unit, Hills Road, Cambridge CB2 0XY, UK.; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, UK.
Pell VR; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, UK.
Gaude E; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Box 197, Cambridge Biomedical Campus, Cambridge, CB2 0XZ, UK.
Aksentijević D; King's College London, British Heart Foundation Centre of Excellence, The Rayne Institute, St Thomas' Hospital, London SE1 7EH, UK.
Sundier SY; Department of Cell and Developmental Biology and UCL Consortium for Mitochondrial Biology, University College London, Gower Street, London WC1E 6BT, UK.
Robb EL; MRC Mitochondrial Biology Unit, Hills Road, Cambridge CB2 0XY, UK.
Logan A; MRC Mitochondrial Biology Unit, Hills Road, Cambridge CB2 0XY, UK.
Nadtochiy SM; Department of Anesthesiology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.
Ord ENJ; Institute of Cardiovascular & Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8TA, UK.
Smith AC; MRC Mitochondrial Biology Unit, Hills Road, Cambridge CB2 0XY, UK.
Eyassu F; MRC Mitochondrial Biology Unit, Hills Road, Cambridge CB2 0XY, UK.
Shirley R; Institute of Cardiovascular & Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8TA, UK.
Hu CH; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, UK.
Dare AJ; MRC Mitochondrial Biology Unit, Hills Road, Cambridge CB2 0XY, UK.
James AM; MRC Mitochondrial Biology Unit, Hills Road, Cambridge CB2 0XY, UK.
Rogatti S; MRC Mitochondrial Biology Unit, Hills Road, Cambridge CB2 0XY, UK.
Hartley RC; School of Chemistry, University of Glasgow, Glasgow, G12 8TA, UK.
Eaton S; Unit of Paediatric Surgery, UCL Institute of Child Health, London, WC1N 1EH, UK.
Costa ASH; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Box 197, Cambridge Biomedical Campus, Cambridge, CB2 0XZ, UK.
Brookes PS; Department of Anesthesiology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.
Davidson SM; Hatter Cardiovascular Institute, University College London, 67 Chenies Mews, London, WC1E 6HX, UK.
Duchen MR; Department of Cell and Developmental Biology and UCL Consortium for Mitochondrial Biology, University College London, Gower Street, London WC1E 6BT, UK.
Saeb-Parsy K; University Department of Surgery and Cambridge NIHR Biomedical Research Centre, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.
Shattock MJ; King's College London, British Heart Foundation Centre of Excellence, The Rayne Institute, St Thomas' Hospital, London SE1 7EH, UK.
Robinson AJ; MRC Mitochondrial Biology Unit, Hills Road, Cambridge CB2 0XY, UK.
Work LM; Institute of Cardiovascular & Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8TA, UK.
Frezza C; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Box 197, Cambridge Biomedical Campus, Cambridge, CB2 0XZ, UK.
Krieg T; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, UK.
Murphy MP; MRC Mitochondrial Biology Unit, Hills Road, Cambridge CB2 0XY, UK.
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Źródło :
Nature [Nature] 2014 Nov 20; Vol. 515 (7527), pp. 431-435. Date of Electronic Publication: 2014 Nov 05.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ischemia/*metabolism
Mitochondria/*metabolism
Reactive Oxygen Species/*metabolism
Reperfusion Injury/*metabolism
Succinic Acid/*metabolism
Adenosine Monophosphate/metabolism ; Animals ; Aspartic Acid/metabolism ; Citric Acid Cycle ; Disease Models, Animal ; Electron Transport ; Electron Transport Complex I/metabolism ; Fumarates/metabolism ; Ischemia/enzymology ; Malates/metabolism ; Male ; Metabolomics ; Mice ; Mitochondria/enzymology ; Myocardial Infarction/enzymology ; Myocardial Infarction/metabolism ; Myocardium/cytology ; Myocardium/enzymology ; Myocardium/metabolism ; Myocytes, Cardiac/enzymology ; Myocytes, Cardiac/metabolism ; NAD/metabolism ; Reperfusion Injury/enzymology ; Stroke/enzymology ; Stroke/metabolism ; Succinate Dehydrogenase/metabolism
Czasopismo naukowe
Tytuł :
Mitochondria selective S-nitrosation by mitochondria-targeted S-nitrosothiol protects against post-infarct heart failure in mouse hearts.
Autorzy :
Methner C; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.
Chouchani ET
Buonincontri G
Pell VR
Sawiak SJ
Murphy MP
Krieg T
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Źródło :
European journal of heart failure [Eur J Heart Fail] 2014 Jul; Vol. 16 (7), pp. 712-7. Date of Electronic Publication: 2014 May 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronary Occlusion*
Free Radicals/*metabolism
Heart/*drug effects
Heart Failure/*metabolism
Mitochondria/*drug effects
Myocardial Infarction/*metabolism
Myocardial Reperfusion Injury/*metabolism
Nitric Oxide Donors/*pharmacology
S-Nitrosothiols/*pharmacology
Animals ; Electron Transport Complex I/antagonists & inhibitors ; Heart Failure/etiology ; Heart Failure/pathology ; Magnetic Resonance Imaging, Cine ; Mice ; Mitochondria/metabolism ; Mitochondrial Proteins/drug effects ; Mitochondrial Proteins/metabolism ; Myocardial Infarction/pathology ; Myocardial Reperfusion Injury/etiology ; Myocardial Reperfusion Injury/pathology ; Myocardium/pathology ; Myocytes, Cardiac/metabolism ; Nitrosation
Czasopismo naukowe
Tytuł :
Using exomarkers to assess mitochondrial reactive species in vivo.
Autorzy :
Logan A; MRC Mitochondrial Biology Unit, Hills Road, Cambridge CB2 0XY, UK.
Cochemé HM
Li Pun PB
Apostolova N
Smith RA
Larsen L
Larsen DS
James AM
Fearnley IM
Rogatti S
Prime TA
Finichiu PG
Dare A
Chouchani ET
Pell VR
Methner C
Quin C
McQuaker SJ
Krieg T
Hartley RC
Murphy MP
Pokaż więcej
Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2014 Feb; Vol. 1840 (2), pp. 923-30. Date of Electronic Publication: 2013 May 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Models, Biological*
Molecular Probes*
Biomarkers/*analysis
Mitochondria/*metabolism
Reactive Oxygen Species/*analysis
Animals ; Mice ; Oxidative Stress
Czasopismo naukowe
Tytuł :
The mitochondrial electron transport chain is dispensable for proliferation and differentiation of epidermal progenitor cells.
Autorzy :
Baris OR; Center for Physiology and Pathophysiology, Institute for Vegetative Physiology,University of Cologne, Cologne, Germany.
Klose A
Kloepper JE
Weiland D
Neuhaus JF
Schauen M
Wille A
Müller A
Merkwirth C
Langer T
Larsson NG
Krieg T
Tobin DJ
Paus R
Wiesner RJ
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Źródło :
Stem cells (Dayton, Ohio) [Stem Cells] 2011 Sep; Vol. 29 (9), pp. 1459-68.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epidermal Cells*
Mitochondria/*metabolism
Stem Cells/*cytology
Stem Cells/*metabolism
Animals ; Apoptosis/physiology ; Cell Differentiation/physiology ; Cell Growth Processes/physiology ; DNA-Binding Proteins/deficiency ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Electron Transport ; Epidermis/metabolism ; Genotype ; High Mobility Group Proteins/deficiency ; High Mobility Group Proteins/genetics ; High Mobility Group Proteins/metabolism ; Immunohistochemistry ; Mice ; Mice, Knockout ; Mitochondria/genetics ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Evidence for an intracellular localization of the adenosine A2B receptor in rat cardiomyocytes.
Autorzy :
Grube K; Department of Cardiology, Ernst-Moritz-Arndt University, Greifswald, Germany.
Rüdebusch J
Xu Z
Böckenholt T
Methner C
Müller T
Cuello F
Zimmermann K
Yang X
Felix SB
Cohen MV
Downey JM
Krieg T
Pokaż więcej
Źródło :
Basic research in cardiology [Basic Res Cardiol] 2011 May; Vol. 106 (3), pp. 385-96. Date of Electronic Publication: 2011 Jan 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Mitochondria/*metabolism
Myocardial Reperfusion Injury/*metabolism
Myocytes, Cardiac/*metabolism
Receptor, Adenosine A2B/*metabolism
Animals ; Blotting, Western ; Female ; Fluorescent Antibody Technique ; Male ; Membrane Potential, Mitochondrial/physiology ; Rats ; Rats, Wistar ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Mitochondria and their role in preconditioning's trigger phase.
Autorzy :
Krieg T; Department of Physiology, MSB 3024, University of South Alabama College of Medicine, Mobile, AL 36688, USA.
Cohen MV
Downey JM
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Źródło :
Basic research in cardiology [Basic Res Cardiol] 2003 Jul; Vol. 98 (4), pp. 228-34.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Ischemic Preconditioning, Myocardial*
Mitochondria/*physiology
Myocardial Ischemia/*metabolism
Myocardial Ischemia/*physiopathology
Animals ; Humans
Czasopismo naukowe
Tytuł :
Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo
Autorzy :
Prag, Hiran A.Aff1, Aff2
Pala, Laura
Kula-Alwar, Duvaraka
Mulvey, John F.
Luping, Du
Beach, Timothy E.
Booty, Lee M.
Hall, Andrew R.
Logan, Angela
Sauchanka, Volha
Caldwell, Stuart T.
Robb, Ellen L.
James, Andrew M.
Xu, Zhelong
Saeb-Parsy, Kourosh
Hartley, Richard C.
Murphy, Michael P.Aff1, Aff2
Krieg, Thomas
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Źródło :
Cardiovascular Drugs and Therapy. :1-13
Czasopismo naukowe

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