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Wyszukujesz frazę ""Krieg, Thomas"" wg kryterium: Autor


Tytuł :
New developments on skin fibrosis - Essential signals emanating from the extracellular matrix for the control of myofibroblasts.
Autorzy :
Schulz JN; Department of Dermatology, University of Cologne, Cologne, Germany.
Plomann M; Center for Biochemistry, University of Cologne, Medical Faculty, Cologne, Germany.
Sengle G; Center for Biochemistry, University of Cologne, Medical Faculty, Cologne, Germany; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
Gullberg D; Department of Biomedicine, Centre for Cancer Biomarkers (CCBIO), University of Bergen, Bergen, Norway.
Krieg T; Department of Dermatology, University of Cologne, Cologne, Germany; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany; Translational Matrix Biology, University of Cologne, Medical Faculty, Cologne, Germany; Cluster of Excellence in Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Eckes B; Department of Dermatology, University of Cologne, Cologne, Germany; Translational Matrix Biology, University of Cologne, Medical Faculty, Cologne, Germany. Electronic address: .
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Źródło :
Matrix biology : journal of the International Society for Matrix Biology [Matrix Biol] 2018 Aug; Vol. 68-69, pp. 522-532. Date of Electronic Publication: 2018 Feb 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Extracellular Matrix/*metabolism
Myofibroblasts/*pathology
Skin/*pathology
Animals ; Fibrosis ; Humans ; Intercellular Signaling Peptides and Proteins/metabolism ; Molecular Targeted Therapy ; Myofibroblasts/metabolism ; Signal Transduction ; Skin/metabolism
Czasopismo naukowe
Tytuł :
COMP-assisted collagen secretion--a novel intracellular function required for fibrosis.
Autorzy :
Schulz JN; Department of Dermatology, University of Cologne, Cologne, Germany.
Nüchel J; Center for Biochemistry, University of Cologne, Germany.
Niehoff A; Cologne Center for Musculoskeletal Biomechanics (CCMB), University of Cologne, Cologne, Germany German Sport University, Cologne, Germany.
Bloch W; German Sport University, Cologne, Germany.
Schönborn K; Department of Dermatology, University of Cologne, Cologne, Germany.
Hayashi S; Department of Dermatology, University of Cologne, Cologne, Germany.
Kamper M; Center for Biochemistry, University of Cologne, Germany.
Brinckmann J; Department of Dermatology, University of Lübeck, Lübeck, Germany Institute of Virology and Cell Biology, University of Lübeck, Lübeck, Germany.
Plomann M; Center for Biochemistry, University of Cologne, Germany.
Paulsson M; Center for Biochemistry, University of Cologne, Germany Cologne Center for Musculoskeletal Biomechanics (CCMB), University of Cologne, Cologne, Germany Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Krieg T; Department of Dermatology, University of Cologne, Cologne, Germany Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Zaucke F; Center for Biochemistry, University of Cologne, Germany Cologne Center for Musculoskeletal Biomechanics (CCMB), University of Cologne, Cologne, Germany .
Eckes B; Department of Dermatology, University of Cologne, Cologne, Germany .
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Źródło :
Journal of cell science [J Cell Sci] 2016 Feb 15; Vol. 129 (4), pp. 706-16. Date of Electronic Publication: 2016 Jan 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cartilage Oligomeric Matrix Protein/*genetics
Fibrillar Collagens/*metabolism
Skin/*metabolism
Animals ; Cartilage Oligomeric Matrix Protein/metabolism ; Cells, Cultured ; Endoplasmic Reticulum Stress ; Female ; Fibroblasts/metabolism ; Fibrosis ; Mice, Inbred C57BL ; Skin/pathology
Czasopismo naukowe
Tytuł :
Cyclic mechanical strain induces TGFβ1-signalling in dermal fibroblasts embedded in a 3D collagen lattice.
Autorzy :
Peters AS; Department of Vascular and Endovascular Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany, .
Brunner G
Krieg T
Eckes B
Pokaż więcej
Źródło :
Archives of dermatological research [Arch Dermatol Res] 2015 Mar; Vol. 307 (2), pp. 191-7. Date of Electronic Publication: 2014 Oct 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Stress, Mechanical*
Fibroblasts/*metabolism
Signal Transduction/*physiology
Skin/*cytology
Transforming Growth Factor beta1/*metabolism
Animals ; Blotting, Western ; Cells, Cultured ; Collagen ; Connective Tissue Growth Factor/metabolism ; Culture Media ; Fibroblasts/pathology ; Fluorescent Antibody Technique, Indirect ; Mice ; RNA/isolation & purification ; Real-Time Polymerase Chain Reaction ; Smad2 Protein/metabolism ; Transforming Growth Factor beta1/genetics
Czasopismo naukowe
Tytuł :
Epidermal RelA specifically restricts contact allergen-induced inflammation and apoptosis in skin.
Autorzy :
Kumari S; Department of Dermatology, University of Cologne, Cologne, Germany. Electronic address: .
Herzberg B; Department of Dermatology, University of Cologne, Cologne, Germany.
Pofahl R; Department of Dermatology, University of Cologne, Cologne, Germany.
Krieg T; Department of Dermatology, University of Cologne, Cologne, Germany.
Haase I; Department of Dermatology, University of Cologne, Cologne, Germany.
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Źródło :
The Journal of investigative dermatology [J Invest Dermatol] 2014 Oct; Vol. 134 (10), pp. 2541-2550. Date of Electronic Publication: 2014 Apr 16.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*physiology
Dermatitis, Allergic Contact/*pathology
Dermatitis, Allergic Contact/*physiopathology
Epidermis/*physiopathology
Skin/*physiopathology
Transcription Factor RelA/*physiology
Animals ; Apoptosis/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Croton Oil/adverse effects ; Croton Oil/pharmacology ; Dermatitis, Allergic Contact/etiology ; Disease Models, Animal ; Epidermis/drug effects ; Epidermis/pathology ; Female ; In Vitro Techniques ; Keratinocytes/drug effects ; Keratinocytes/pathology ; Keratinocytes/physiology ; Mice ; Mice, Inbred C57BL ; Mutation/genetics ; NF-kappa B/physiology ; S100 Proteins/physiology ; Signal Transduction/drug effects ; Signal Transduction/physiology ; Skin/drug effects ; Skin/pathology ; Transcription Factor RelA/genetics
Czasopismo naukowe
Tytuł :
Molecular and cellular basis of scleroderma.
Autorzy :
Eckes B; Department of Dermatology, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Moinzadeh P
Sengle G
Hunzelmann N
Krieg T
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Źródło :
Journal of molecular medicine (Berlin, Germany) [J Mol Med (Berl)] 2014 Sep; Vol. 92 (9), pp. 913-24. Date of Electronic Publication: 2014 Jul 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Extracellular Matrix/*pathology
Fibroblasts/*pathology
Scleroderma, Systemic/*pathology
Skin/*pathology
Animals ; Extracellular Matrix/genetics ; Extracellular Matrix/immunology ; Fibroblasts/immunology ; Fibroblasts/metabolism ; Fibrosis ; Humans ; Inflammation/complications ; Inflammation/immunology ; Inflammation/pathology ; Scleroderma, Systemic/complications ; Scleroderma, Systemic/genetics ; Scleroderma, Systemic/immunology ; Signal Transduction ; Skin/blood supply ; Skin/immunology ; Skin/metabolism
Czasopismo naukowe
Tytuł :
Vascular endothelial insulin/IGF-1 signaling controls skin wound vascularization.
Autorzy :
Aghdam SY; Department of Dermatology, University of Cologne, Germany.
Eming SA
Willenborg S
Neuhaus B
Niessen CM
Partridge L
Krieg T
Bruning JC
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2012 May 04; Vol. 421 (2), pp. 197-202. Date of Electronic Publication: 2012 Apr 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neovascularization, Physiologic*
Wound Healing*
Diabetes Mellitus, Type 2/*physiopathology
Endothelium, Vascular/*physiopathology
Insulin/*physiology
Insulin-Like Growth Factor I/*physiology
Skin/*blood supply
Animals ; Diabetes Mellitus, Type 2/pathology ; Endothelium, Vascular/pathology ; Granulation Tissue/pathology ; Granulation Tissue/physiopathology ; Homeostasis ; Mice ; Mice, Inbred C57BL ; Skin/pathology
Czasopismo naukowe
Tytuł :
Pivotal role for alpha1-antichymotrypsin in skin repair.
Autorzy :
Hoffmann DC; Department of Dermatology, University of Cologne, 50931 Cologne, Germany.
Textoris C
Oehme F
Klaassen T
Goppelt A
Römer A
Fugmann B
Davidson JM
Werner S
Krieg T
Eming SA
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2011 Aug 19; Vol. 286 (33), pp. 28889-901. Date of Electronic Publication: 2011 Jun 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Peptides/*metabolism
Serpins/*metabolism
Skin/*metabolism
Wound Healing/*physiology
Animals ; Humans ; Intracellular Signaling Peptides and Proteins ; Leukocyte Elastase/genetics ; Leukocyte Elastase/metabolism ; Mice ; Peptides/genetics ; Serpins/genetics ; Skin/injuries
Czasopismo naukowe
Tytuł :
Expression of integrin beta1 by fibroblasts is required for tissue repair in vivo.
Autorzy :
Liu S; The Canadian Institute of Health Research Group in Skeletal Development and Remodeling, Division of Oral Biology and Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, Dental Sciences Building, London, ON N6A 5C1, Canada.
Xu SW
Blumbach K
Eastwood M
Denton CP
Eckes B
Krieg T
Abraham DJ
Leask A
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Źródło :
Journal of cell science [J Cell Sci] 2010 Nov 01; Vol. 123 (Pt 21), pp. 3674-82. Date of Electronic Publication: 2010 Oct 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fibroblasts/*metabolism
Integrin beta1/*metabolism
Myofibroblasts/*metabolism
Skin/*metabolism
Stress Fibers/*metabolism
Actins/genetics ; Actins/metabolism ; Animals ; Cell Differentiation/genetics ; Cells, Cultured ; Collagen Type I/biosynthesis ; Collagen Type I/genetics ; Connective Tissue Growth Factor/genetics ; Connective Tissue Growth Factor/metabolism ; Fibroblasts/pathology ; Focal Adhesions/genetics ; Gene Expression Regulation/genetics ; Humans ; Integrin beta1/genetics ; Mice ; Mice, Knockout ; Myofibroblasts/pathology ; Sequence Deletion/genetics ; Skin/injuries ; Skin/pathology ; Stress Fibers/genetics ; Wound Healing
Czasopismo naukowe
Tytuł :
Differential roles of macrophages in diverse phases of skin repair.
Autorzy :
Lucas T; Department of Dermatology, University of Cologne, Cologne, Germany.
Waisman A
Ranjan R
Roes J
Krieg T
Müller W
Roers A
Eming SA
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2010 Apr 01; Vol. 184 (7), pp. 3964-77. Date of Electronic Publication: 2010 Feb 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Skin Physiological Phenomena*
Macrophages/*physiology
Skin/*injuries
Wound Healing/*physiology
Animals ; Cell Separation ; Flow Cytometry ; Immunohistochemistry ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Merkel cell polyomavirus DNA in persons without merkel cell carcinoma.
Autorzy :
Wieland U; Institute of Virology, University of Cologne, Koeln, Germany. />Mauch C
Kreuter A
Krieg T
Pfister H
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Źródło :
Emerging infectious diseases [Emerg Infect Dis] 2009 Sep; Vol. 15 (9), pp. 1496-8.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Merkel Cell/*virology
DNA, Viral/*isolation & purification
Eyebrows/*virology
Polyomavirus/*isolation & purification
Polyomavirus Infections/*virology
Skin/*virology
Tumor Virus Infections/*virology
DNA, Viral/analysis ; Forehead/virology ; Genitalia, Male/virology ; HIV Seropositivity ; Humans ; Male ; Mouth/virology ; Polyomavirus/genetics
Czasopismo naukowe
Tytuł :
Integrin alpha2beta1 is required for regulation of murine wound angiogenesis but is dispensable for reepithelialization.
Autorzy :
Zweers MC; Department of Dermatology, University of Cologne, Cologne, Germany. />Davidson JM
Pozzi A
Hallinger R
Janz K
Quondamatteo F
Leutgeb B
Krieg T
Eckes B
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Źródło :
The Journal of investigative dermatology [J Invest Dermatol] 2007 Feb; Vol. 127 (2), pp. 467-78. Date of Electronic Publication: 2006 Sep 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Wound Healing*
Integrin alpha2beta1/*metabolism
Skin/*injuries
Wounds, Penetrating/*physiopathology
Animals ; Cells, Cultured ; Cicatrix/pathology ; Collagen/metabolism ; Epithelium/physiopathology ; Fibroblasts ; Integrin alpha2beta1/deficiency ; Integrins/metabolism ; Mast Cells/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Neovascularization, Physiologic ; Skin/pathology ; Skin/physiopathology ; Wounds, Penetrating/pathology
Czasopismo naukowe
Tytuł :
Morphometric analysis of murine skin wound healing: standardization of experimental procedures and impact of an advanced multitissue array technique.
Autorzy :
Gerharz M; Institute of Pathology, University of Cologne, Cologne, Germany.
Baranowsky A
Siebolts U
Eming S
Nischt R
Krieg T
Wickenhauser C
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Źródło :
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society [Wound Repair Regen] 2007 Jan-Feb; Vol. 15 (1), pp. 105-12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Tissue Array Analysis*
Biopsy, Needle/*methods
Skin/*injuries
Specimen Handling/*standards
Wound Healing/*physiology
Wounds, Penetrating/*pathology
Animals ; Biopsy, Needle/instrumentation ; Disease Models, Animal ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Sex Factors ; Wounds, Penetrating/etiology ; Wounds, Penetrating/physiopathology
Czasopismo naukowe
Tytuł :
Localized inflammatory skin disease following inducible ablation of I kappa B kinase 2 in murine epidermis.
Autorzy :
Stratis A; Department of Dermatology, University of Cologne and Center for Molecular Medicine, University of Cologne (CMMC), Cologne, Germany.
Pasparakis M
Markur D
Knaup R
Pofahl R
Metzger D
Chambon P
Krieg T
Haase I
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Źródło :
The Journal of investigative dermatology [J Invest Dermatol] 2006 Mar; Vol. 126 (3), pp. 614-20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Deletion*
Dermatitis/*etiology
I-kappa B Kinase/*genetics
Skin/*metabolism
Animals ; Cell Differentiation ; Cell Proliferation ; Dermatitis/pathology ; Hair Follicle/pathology ; Integrases/physiology ; Keratin-14 ; Keratinocytes/physiology ; Keratins/genetics ; Mice ; Mice, Inbred C57BL ; STAT3 Transcription Factor/physiology ; Skin/pathology ; Tamoxifen/pharmacology
Czasopismo naukowe
Tytuł :
Overexpression of phospholipid-hydroperoxide glutathione peroxidase in human dermal fibroblasts abrogates UVA irradiation-induced expression of interstitial collagenase/matrix metalloproteinase-1 by suppression of phosphatidylcholine hydroperoxide-mediated NFkappaB activation and interleukin-6 release.
Autorzy :
Wenk J; Department of Dermatology, University of Cologne, 50924 Cologne, Germany.
Schüller J
Hinrichs C
Syrovets T
Azoitei N
Podda M
Wlaschek M
Brenneisen P
Schneider LA
Sabiwalsky A
Peters T
Sulyok S
Dissemond J
Schauen M
Krieg T
Wirth T
Simmet T
Scharffetter-Kochanek K
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2004 Oct 29; Vol. 279 (44), pp. 45634-42. Date of Electronic Publication: 2004 Aug 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ultraviolet Rays*
Collagenases/*genetics
Gene Expression Regulation, Enzymologic/*radiation effects
Glutathione Peroxidase/*physiology
Interleukin-6/*biosynthesis
Matrix Metalloproteinase 1/*genetics
NF-kappa B/*metabolism
Phosphatidylcholines/*physiology
Skin/*radiation effects
Active Transport, Cell Nucleus ; Cell Line ; Fibroblasts/metabolism ; Fibroblasts/radiation effects ; Humans ; Phospholipid Hydroperoxide Glutathione Peroxidase ; RNA, Messenger/analysis ; Skin/cytology ; Skin/metabolism
Czasopismo naukowe
Tytuł :
Expression of matrilin-2 in human skin.
Autorzy :
Piecha D; Department of Dermatology, Medical Faculty, University of Cologne, Joseph-Stelzmann-Strasse 9, 50931 Cologne, Germany.
Hartmann K
Kobbe B
Haase I
Mauch C
Krieg T
Paulsson M
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Źródło :
The Journal of investigative dermatology [J Invest Dermatol] 2002 Jul; Vol. 119 (1), pp. 38-43.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Extracellular Matrix Proteins/*genetics
Fibroblasts/*physiology
Glycoproteins/*genetics
Keratinocytes/*physiology
Skin/*cytology
Adult ; Blotting, Northern ; Cells, Cultured ; Extracellular Matrix Proteins/analysis ; Fibroblasts/cytology ; Gene Expression/physiology ; Glycoproteins/analysis ; Humans ; Immunohistochemistry ; In Situ Hybridization ; Infant ; Keratinocytes/cytology ; Matrilin Proteins ; Middle Aged ; RNA, Messenger/analysis
Czasopismo naukowe

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