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    Wyświetlanie 1-9 z 9
    Tytuł:
    Splenic Abscess in an Adolescent due to Salmonella enterica Conservatively Treated with Ultrasound-Guided Fine-Needle Aspiration.
    Autorzy:
    Jørgensen ASS; Department of Paediatrics, Viborg Regional Hospital, Viborg, Denmark.
    Arsic I; Department of Radiology, Viborg Regional Hospital, Viborg, Denmark.
    Pedersen N; Department of Radiology, Viborg Regional Hospital, Viborg, Denmark.
    Kristensen LH; Department of Internal Medicine, Viborg Regional Hospital, Viborg, Denmark.
    Nielsen MF; Department of Surgery, University Hospital of Southern Denmark, Odense, Denmark.
    Balslev T; Department of Paediatrics, Viborg Regional Hospital, Viborg, Denmark.
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    Źródło:
    Case reports in pediatrics [Case Rep Pediatr] 2023 Mar 13; Vol. 2023, pp. 8802760. Date of Electronic Publication: 2023 Mar 13 (Print Publication: 2023).
    Typ publikacji:
    Case Reports
    Raport
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Altered balance between collagen formation and degradation after successful direct-acting antiviral therapy of chronic hepatitis C.
    Autorzy:
    Laursen TL; Department of Hepatology & Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
    Villesen IF; Nordic Bioscience, Herlev, Denmark.
    Leeming DJ; Nordic Bioscience, Herlev, Denmark.
    Karsdal MA; Nordic Bioscience, Herlev, Denmark.
    Sølund C; Department of Infectious Diseases, Hvidovre Hospital, Hvidovre, Denmark.
    Tarp B; Diagnostic Centre, Silkeborg Regional Hospital, Silkeborg, Denmark.
    Kristensen LH; Department of Medicine, Viborg Regional Hospital, Viborg, Denmark.
    Holmboe CH; Department of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark.
    Leutscher P; Centre for Clinical Research, North Denmark Regional Hospital & Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
    Laursen AL; Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.
    Gudmann NS; Nordic Bioscience, Herlev, Denmark.
    Grønbaek H; Department of Hepatology & Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
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    Źródło:
    Journal of viral hepatitis [J Viral Hepat] 2021 Feb; Vol. 28 (2), pp. 236-244. Date of Electronic Publication: 2020 Nov 02.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antiviral Agents*/therapeutic use
    Hepatitis C, Chronic*/drug therapy
    Biomarkers ; Collagen ; Complement C4 ; Humans ; Liver Cirrhosis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Time-dependent improvement of liver inflammation, fibrosis and metabolic liver function after successful direct-acting antiviral therapy of chronic hepatitis C.
    Autorzy:
    Laursen TL; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
    Siggaard CB; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
    Kazankov K; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
    Sandahl TD; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
    Møller HJ; Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark.
    Tarp B; Diagnostic Centre, Silkeborg Regional Hospital, Silkeborg, Denmark.
    Kristensen LH; Department of Medicine, Viborg Regional Hospital, Viborg, Denmark.
    Laursen AL; Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.
    Leutscher P; Centre for Clinical Research, North Denmark Regional Hospital, Hjørring, Denmark.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
    Grønbaek H; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
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    Źródło:
    Journal of viral hepatitis [J Viral Hepat] 2020 Jan; Vol. 27 (1), pp. 28-35. Date of Electronic Publication: 2019 Oct 02.
    Typ publikacji:
    Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antiviral Agents/*therapeutic use
    Hepatitis C, Chronic/*drug therapy
    Inflammation/*physiopathology
    Liver/*drug effects
    Liver/*pathology
    Liver Cirrhosis/*physiopathology
    Elasticity Imaging Techniques ; Female ; Humans ; Inflammation/drug therapy ; Liver/immunology ; Liver Function Tests ; Male ; Middle Aged ; Prospective Studies ; Sofosbuvir/therapeutic use ; Sustained Virologic Response ; Time Factors ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Molecular architecture of the Jumonji C family histone demethylase KDM5B.
    Autorzy:
    Dorosz J; Biostructural Research, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100, Copenhagen, Denmark.
    Kristensen LH; Biostructural Research, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100, Copenhagen, Denmark.
    Aduri NG; Biostructural Research, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100, Copenhagen, Denmark.
    Mirza O; Biostructural Research, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100, Copenhagen, Denmark.
    Lousen R; Biostructural Research, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100, Copenhagen, Denmark.
    Bucciarelli S; Biostructural Research, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100, Copenhagen, Denmark.
    Mehta V; Biostructural Research, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100, Copenhagen, Denmark.
    Sellés-Baiget S; Biostructural Research, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100, Copenhagen, Denmark.
    Solbak SMØ; Medicinal Chemistry Research, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100, Copenhagen, Denmark.
    Bach A; Medicinal Chemistry Research, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100, Copenhagen, Denmark.
    Mesa P; Protein Structure & Function Programme, Macromolecular Crystallography Group, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, Copenhagen, 2200, Denmark.
    Hernandez PA; Protein Structure & Function Programme, Macromolecular Crystallography Group, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, Copenhagen, 2200, Denmark.
    Montoya G; Protein Structure & Function Programme, Macromolecular Crystallography Group, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, Copenhagen, 2200, Denmark.
    Nguyen TTTN; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark.
    Rand KD; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark.
    Boesen T; Interdisciplinary Nanoscience Center, Aarhus University, Gustav Wieds Vej 14, 8000, Aarhus, Denmark.
    Gajhede M; Biostructural Research, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, 2100, Copenhagen, Denmark. .
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    Źródło:
    Scientific reports [Sci Rep] 2019 Mar 11; Vol. 9 (1), pp. 4019. Date of Electronic Publication: 2019 Mar 11.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Jumonji Domain-Containing Histone Demethylases/*chemistry
    Nuclear Proteins/*chemistry
    Repressor Proteins/*chemistry
    Co-Repressor Proteins/chemistry ; Demethylation ; Histone Demethylases/chemistry ; Humans ; Nerve Tissue Proteins/chemistry ; Protein Domains
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Fusobacterium necrophorum findings in Denmark from 2010 to 2014 using data from the Danish microbiology database.
    Autorzy:
    Bank S; Department of Medicine, Viborg Regional Hospital, Viborg, Denmark.
    Jensen A; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
    Nielsen HM; Department of Microbiology, Viborg Regional Hospital, Viborg, Denmark.
    Kristensen LH; Department of Medicine, Viborg Regional Hospital, Viborg, Denmark.
    Voldstedlund M; Infectious Disease Epidemiology, Statens Serum Institut, Copenhagen, Denmark.
    Prag J; Department of Microbiology, Viborg Regional Hospital, Viborg, Denmark.
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    Źródło:
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica [APMIS] 2016 Dec; Vol. 124 (12), pp. 1087-1092. Date of Electronic Publication: 2016 Oct 05.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Bacteremia/*epidemiology
    Carrier State/*epidemiology
    Fusobacterium Infections/*epidemiology
    Fusobacterium necrophorum/*isolation & purification
    Otitis Media/*epidemiology
    Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Bacteremia/microbiology ; Blood/microbiology ; Carrier State/microbiology ; Child ; Child, Preschool ; Denmark/epidemiology ; Female ; Fusobacterium Infections/microbiology ; Humans ; Incidence ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Otitis Media/microbiology ; Pharynx/microbiology ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Structure and binding properties of a cameloid nanobody raised against KDM5B.
    Autorzy:
    Wiuf A; Department of Drug Design and Pharmacology, University of Copenhagen, 2200 Copenhagen, Denmark.
    Kristensen LH; Department of Drug Design and Pharmacology, University of Copenhagen, 2200 Copenhagen, Denmark.
    Kristensen O; Department of Drug Design and Pharmacology, University of Copenhagen, 2200 Copenhagen, Denmark.
    Dorosz J; Department of Drug Design and Pharmacology, University of Copenhagen, 2200 Copenhagen, Denmark.
    Jensen J; Department of Drug Design and Pharmacology, University of Copenhagen, 2200 Copenhagen, Denmark.
    Gajhede M; Department of Drug Design and Pharmacology, University of Copenhagen, 2200 Copenhagen, Denmark.
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    Źródło:
    Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2015 Oct; Vol. 71 (Pt 10), pp. 1235-41. Date of Electronic Publication: 2015 Sep 23.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Jumonji Domain-Containing Histone Demethylases/*immunology
    Nuclear Proteins/*immunology
    Repressor Proteins/*immunology
    Single-Domain Antibodies/*chemistry
    Single-Domain Antibodies/*metabolism
    Amino Acid Sequence ; Animals ; Camelus ; Chromatography, Gel ; Crystallization ; Crystallography, X-Ray ; Humans ; Jumonji Domain-Containing Histone Demethylases/chemistry ; Jumonji Domain-Containing Histone Demethylases/metabolism ; Molecular Sequence Data ; Nuclear Proteins/chemistry ; Nuclear Proteins/metabolism ; Protein Binding ; Repressor Proteins/chemistry ; Repressor Proteins/metabolism ; Temperature
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Testing for hepatitis B virus and HIV in patients with chronic hepatitis C: screening performance and outcome.
    Autorzy:
    Bolther M; From the Department of Infectious Diseases, Aarhus University Hospital.
    Dalgaard LS
    Kristensen LH
    Tarp BD
    Jensen-Fangel S
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    Źródło:
    Scandinavian journal of infectious diseases [Scand J Infect Dis] 2014 Oct; Vol. 46 (10), pp. 686-92. Date of Electronic Publication: 2014 Aug 19.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Clinical Laboratory Techniques/*statistics & numerical data
    HIV Infections/*diagnosis
    Hepatitis B/*diagnosis
    Hepatitis C, Chronic/*complications
    Mass Screening/*statistics & numerical data
    Adult ; Cohort Studies ; Coinfection/diagnosis ; Coinfection/epidemiology ; Cross-Sectional Studies ; Denmark ; Female ; HIV Infections/epidemiology ; Hepatitis B/epidemiology ; Hospitals, University ; Humans ; Male ; Prevalence ; Serologic Tests/statistics & numerical data ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor.
    Autorzy:
    Kristensen LH; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
    Nielsen AL
    Helgstrand C
    Lees M
    Cloos P
    Kastrup JS
    Helin K
    Olsen L
    Gajhede M
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    Źródło:
    The FEBS journal [FEBS J] 2012 Jun; Vol. 279 (11), pp. 1905-14. Date of Electronic Publication: 2012 May 02.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Enzyme Inhibitors/*pharmacology
    Histones/*metabolism
    Jumonji Domain-Containing Histone Demethylases/*metabolism
    Nuclear Proteins/*metabolism
    Pyridines/*pharmacology
    Repressor Proteins/*metabolism
    Amino Acid Sequence ; Baculoviridae ; Cell Line, Tumor ; Chromatin/genetics ; Chromatin/metabolism ; Histone Methyltransferases ; Histone-Lysine N-Methyltransferase/metabolism ; Humans ; Jumonji Domain-Containing Histone Demethylases/antagonists & inhibitors ; Jumonji Domain-Containing Histone Demethylases/genetics ; Kinetics ; Lysine/metabolism ; Models, Molecular ; Molecular Sequence Data ; Nuclear Proteins/antagonists & inhibitors ; Nuclear Proteins/genetics ; Osteosarcoma/metabolism ; Osteosarcoma/pathology ; Protein Isoforms/antagonists & inhibitors ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Recombinant Proteins/antagonists & inhibitors ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Repressor Proteins/antagonists & inhibitors ; Repressor Proteins/genetics ; Substrate Specificity ; Transfection
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-9 z 9

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