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    Wyświetlanie 1-7 z 7
    Tytuł:
    Cognitive dysfunction predicts worse health-related quality of life for older stroke survivors: a nationwide population-based survey in Taiwan.
    Autorzy:
    Kuo LM; a Department of Gerontological Health Care, College of Nursing , National Taipei University of Nursing and Health Sciences , Taipei , Taiwan.
    Tsai WC; b Department of Psychiatry , College of Medicine, National Taiwan University , Taipei , Taiwan.
    Chiu MJ; c Department of Neurology, National Taiwan University Hospital, College of Medicine , National Taiwan University , Taipei , Taiwan.; d Graduate Institute of Brain and Mind Sciences , National Taiwan University , Taipei , Taiwan.; e Graduate Institute of Psychology , National Taiwan University , Taipei , Taiwan.; f Graduate Institute of Biomedical Engineering and Bioinformatics , National Taiwan University , Taipei , Taiwan.
    Tang LY; g Taiwan Alzheimer's Disease Association , Taipei , Taiwan.
    Lee HJ; g Taiwan Alzheimer's Disease Association , Taipei , Taiwan.
    Shyu YL; h School of Nursing, College of Medicine , Chang Gung University , Taoyuan , Taiwan.; i Department of Orthopedic Surgery , Linkou Chang Gung Memorial Hospital , Taoyuan , Taiwan.; j Department of Nursing , Kaohsiung Chang Gung Memorial Hospital , Kaohsiung , Taiwan.; k Department of Gerontological Care and Management , Chang Gung University of Science and Technology , Taoyuan , Taiwan.
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    Źródło:
    Aging & mental health [Aging Ment Health] 2019 Mar; Vol. 23 (3), pp. 305-310. Date of Electronic Publication: 2017 Dec 21.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Activities of Daily Living/*psychology
    Cognitive Dysfunction/*psychology
    Quality of Life/*psychology
    Stroke/*psychology
    Aged ; Aged, 80 and over ; Cognitive Dysfunction/complications ; Comorbidity ; Female ; Humans ; Hypertension/complications ; Hypertension/epidemiology ; Male ; Stroke/complications ; Surveys and Questionnaires ; Survivors ; Taiwan/epidemiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Honokiol suppresses TNF-α-induced neutrophil adhesion on cerebral endothelial cells by disrupting polyubiquitination and degradation of IκBα.
    Autorzy:
    Chen PJ; Graduate Institute of Natural Products, School of Traditional Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Chinese Herbal Medicine Research Team, Healthy Aging Research Center, Chang Gung University, Taoyuan 333, Taiwan.
    Wang YL; Graduate Institute of Natural Products, School of Traditional Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Chinese Herbal Medicine Research Team, Healthy Aging Research Center, Chang Gung University, Taoyuan 333, Taiwan.
    Kuo LM; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Department of General Surgery, Chang Gung Memorial Hospital, Chiayi 613, Taiwan.
    Lin CF; Research Center for Industry of Human Ecology and Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan.
    Chen CY; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Department of Anaesthesiology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
    Tsai YF; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Department of Anaesthesiology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
    Shen JJ; Graduate Institute of Natural Products, School of Traditional Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Chinese Herbal Medicine Research Team, Healthy Aging Research Center, Chang Gung University, Taoyuan 333, Taiwan.
    Hwang TL; Graduate Institute of Natural Products, School of Traditional Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Chinese Herbal Medicine Research Team, Healthy Aging Research Center, Chang Gung University, Taoyuan 333, Taiwan.; Research Center for Industry of Human Ecology and Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan.; Department of Anaesthesiology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
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    Źródło:
    Scientific reports [Sci Rep] 2016 May 23; Vol. 6, pp. 26554. Date of Electronic Publication: 2016 May 23.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Biphenyl Compounds/*pharmacology
    Brain/*cytology
    Lignans/*pharmacology
    NF-KappaB Inhibitor alpha/*metabolism
    Neutrophils/*cytology
    Tumor Necrosis Factor-alpha/*metabolism
    Animals ; Cell Adhesion/drug effects ; Cells, Cultured ; Endothelial Cells/cytology ; Gene Expression Regulation/drug effects ; Humans ; Mice ; NF-KappaB Inhibitor alpha/chemistry ; Neutrophils/drug effects ; Proteolysis/drug effects ; Ubiquitination/drug effects ; Vascular Cell Adhesion Molecule-1/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Inflammation Promotes Expression of Stemness-Related Properties in HBV-Related Hepatocellular Carcinoma.
    Autorzy:
    Chang TS; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.
    Chen CL; Department of Pathology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.; Department of Pathology, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan.; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
    Wu YC; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.; TMU Center for Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, Taiwan.
    Liu JJ; School of Medical Laboratory Sciences and Biotechnology, Taipei Medical University, Taipei, Taiwan.
    Kuo YC; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.; TMU Center for Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, Taiwan.
    Lee KF; Department of Pathology, Chang Gung Memorial Hospital, Chiayi, Taiwan.
    Lin SY; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
    Lin SE; Department of Pathology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
    Tung SY; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.
    Kuo LM; Department of General Surgery, Chang Gung Memorial Hospital, Chiayi, Taiwan.
    Tsai YH; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.
    Huang YH; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.; TMU Center for Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, Taiwan.; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan.; Center for Reproductive Medicine, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan.; Comprehensive Cancer Center of Taipei Medical University, Taipei, Taiwan.; Ph.D. Program for Translational Medicine, Taipei Medical University, Taipei, Taiwan.
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    Źródło:
    PloS one [PLoS One] 2016 Feb 26; Vol. 11 (2), pp. e0149897. Date of Electronic Publication: 2016 Feb 26 (Print Publication: 2016).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Carcinoma, Hepatocellular/*pathology
    Hepatitis B, Chronic/*complications
    Liver Neoplasms/*pathology
    Neoplastic Stem Cells/*pathology
    Octamer Transcription Factor-3/*biosynthesis
    Antigens, CD/biosynthesis ; Antigens, CD/genetics ; Antigens, Differentiation, Myelomonocytic/biosynthesis ; Antigens, Differentiation, Myelomonocytic/genetics ; Carcinoma, Hepatocellular/virology ; Cell Movement ; Cell Proliferation ; Cell Survival ; Chemokine CCL2/biosynthesis ; Chemokine CCL2/genetics ; Hep G2 Cells ; Hepatitis B virus/pathogenicity ; Homeodomain Proteins/biosynthesis ; Homeodomain Proteins/genetics ; Humans ; Inflammation/immunology ; Inflammation/pathology ; Insulin-Like Growth Factor I/biosynthesis ; Liver Neoplasms/virology ; Nanog Homeobox Protein ; Octamer Transcription Factor-3/genetics ; Phosphorylation/drug effects ; Podophyllotoxin/analogs & derivatives ; Podophyllotoxin/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; Receptor, IGF Type 1/biosynthesis ; Receptor, IGF Type 1/metabolism ; Signal Transduction ; Spheroids, Cellular ; Tumor Cells, Cultured
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Anti-inflammatory effects of Perilla frutescens in activated human neutrophils through two independent pathways: Src family kinases and Calcium.
    Autorzy:
    Chen CY; Graduate Institute of Natural Products, School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
    Leu YL; Graduate Institute of Natural Products, School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
    Fang Y; Graduate Institute of Natural Products, School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
    Lin CF; Department of Cosmetic Science, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan.
    Kuo LM; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Division of General Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi, Taiwan.
    Sung WC; Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
    Tsai YF; Graduate Institute of Natural Products, School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
    Chung PJ; Graduate Institute of Natural Products, School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
    Lee MC; Brion Research Institute of Taiwan, New Taipei City 231, Taiwan.
    Kuo YT; Graduate Institute of Natural Products, School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
    Yang HW; Graduate Institute of Natural Products, School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
    Hwang TL; Graduate Institute of Natural Products, School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Chinese Herbal Medicine Research Team, Healthy Aging Research Center, Chang Gung University, Kweishan, Taoyuan 333, Taiwan.; Department of Cosmetic Science and Research Center for Industry of Human Ecology, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan.
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    Źródło:
    Scientific reports [Sci Rep] 2015 Dec 14; Vol. 5, pp. 18204. Date of Electronic Publication: 2015 Dec 14.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Anti-Inflammatory Agents/*pharmacology
    Calcium/*metabolism
    Neutrophils/*drug effects
    Neutrophils/*metabolism
    Perilla frutescens/*chemistry
    Plant Extracts/*pharmacology
    Signal Transduction/*drug effects
    src-Family Kinases/*metabolism
    Agammaglobulinaemia Tyrosine Kinase ; CD11b Antigen/metabolism ; Humans ; N-Formylmethionine Leucyl-Phenylalanine/pharmacology ; Pancreatic Elastase/metabolism ; Phosphorylation ; Protein-Tyrosine Kinases/metabolism ; Reactive Oxygen Species/metabolism ; Superoxides/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Intracellular glutathione depletion by oridonin leads to apoptosis in hepatic stellate cells.
    Autorzy:
    Kuo LM; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan. .
    Kuo CY; Graduate Institute of Natural Products, School of Traditional Chinese Medicine, Collage of Medicine, Chang Gung University, Taoyuan 333, Taiwan. .
    Lin CY; Graduate Institute of Natural Products, School of Traditional Chinese Medicine, Collage of Medicine, Chang Gung University, Taoyuan 333, Taiwan. .
    Hung MF; Graduate Institute of Natural Products, School of Traditional Chinese Medicine, Collage of Medicine, Chang Gung University, Taoyuan 333, Taiwan. .
    Shen JJ; Graduate Institute of Natural Products, School of Traditional Chinese Medicine, Collage of Medicine, Chang Gung University, Taoyuan 333, Taiwan. .
    Hwang TL; Graduate Institute of Natural Products, School of Traditional Chinese Medicine, Collage of Medicine, Chang Gung University, Taoyuan 333, Taiwan. .
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    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2014 Mar 18; Vol. 19 (3), pp. 3327-44. Date of Electronic Publication: 2014 Mar 18.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Apoptosis/*drug effects
    Diterpenes, Kaurane/*pharmacology
    Glutathione/*metabolism
    Hepatic Stellate Cells/*drug effects
    Hepatic Stellate Cells/*metabolism
    Animals ; Caspase 3/metabolism ; Cell Line ; Cell Survival/drug effects ; Enzyme Activation/drug effects ; Inhibitory Concentration 50 ; Intracellular Space/metabolism ; Membrane Potential, Mitochondrial/drug effects ; Mitogen-Activated Protein Kinases/metabolism ; Oxidative Stress ; Phosphorylation ; Rats ; Reactive Oxygen Species/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    New benzo[c]phenanthridine and benzenoid derivatives, and other constituents from Zanthoxylum ailanthoides: Effects on neutrophil pro-inflammatory responses.
    Autorzy:
    Chung CY; Faculty of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan. .
    Hwang TL
    Kuo LM
    Kuo WL
    Cheng MJ
    Wu YH
    Sung PJ
    Chung MI
    Chen JJ
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2013 Nov 13; Vol. 14 (11), pp. 22395-408. Date of Electronic Publication: 2013 Nov 13.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Benzoates/*chemistry
    Benzophenanthridines/*pharmacology
    Cinnamates/*chemistry
    Hydroxybutyrates/*chemistry
    Neutrophils/*drug effects
    Zanthoxylum/*chemistry
    Benzophenanthridines/chemistry ; Benzophenanthridines/isolation & purification ; Humans ; Superoxides/antagonists & inhibitors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-7 z 7

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