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Tytuł :
Lactate induces vascular permeability via disruption of VE-cadherin in endothelial cells during sepsis.
Autorzy :
Yang K; Department of Surgery, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.; Center of Excellence in Inflammation, Infectious Disease, and Immunity, East Tennessee State University, Johnson City, TN 37614, USA.
Fan M; Department of Surgery, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.; Center of Excellence in Inflammation, Infectious Disease, and Immunity, East Tennessee State University, Johnson City, TN 37614, USA.
Wang X; Department of Surgery, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.; Center of Excellence in Inflammation, Infectious Disease, and Immunity, East Tennessee State University, Johnson City, TN 37614, USA.
Xu J; Department of Surgery, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
Wang Y; Department of Surgery, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
Gill PS; Department of Surgery, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
Ha T; Department of Surgery, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.; Center of Excellence in Inflammation, Infectious Disease, and Immunity, East Tennessee State University, Johnson City, TN 37614, USA.
Liu L; Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.
Hall JV; Department of Surgery, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.; Center of Excellence in Inflammation, Infectious Disease, and Immunity, East Tennessee State University, Johnson City, TN 37614, USA.
Williams DL; Department of Surgery, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.; Center of Excellence in Inflammation, Infectious Disease, and Immunity, East Tennessee State University, Johnson City, TN 37614, USA.
Li C; Department of Surgery, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.; Center of Excellence in Inflammation, Infectious Disease, and Immunity, East Tennessee State University, Johnson City, TN 37614, USA.
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Źródło :
Science advances [Sci Adv] 2022 Apr 29; Vol. 8 (17), pp. eabm8965. Date of Electronic Publication: 2022 Apr 27.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, CD*/metabolism
Cadherins*/metabolism
Capillary Permeability*
Lactates*/metabolism
Sepsis*/metabolism
Sepsis*/pathology
Endothelial Cells/metabolism ; Humans
Czasopismo naukowe
Tytuł :
Murburn precepts for lactic-acidosis, Cori cycle, and Warburg effect: Interactive dynamics of dehydrogenases, protons, and oxygen.
Autorzy :
Manoj KM; Department of Biochemistry, Satyamjayatu: The Science & Ethics Foundation, Palakkad, Kerala, India.
Nirusimhan V; Department of Biochemistry, Satyamjayatu: The Science & Ethics Foundation, Palakkad, Kerala, India.
Parashar A; Department of Biochemistry, Satyamjayatu: The Science & Ethics Foundation, Palakkad, Kerala, India.
Edward J; Department of Biochemistry, Satyamjayatu: The Science & Ethics Foundation, Palakkad, Kerala, India.
Gideon DA; Department of Biochemistry, Satyamjayatu: The Science & Ethics Foundation, Palakkad, Kerala, India.
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Źródło :
Journal of cellular physiology [J Cell Physiol] 2022 Mar; Vol. 237 (3), pp. 1902-1922. Date of Electronic Publication: 2021 Dec 20.
Typ publikacji :
Journal Article
MeSH Terms :
Acidosis*
Lactates*/metabolism
Liver*/metabolism
Oxygen*/metabolism
Humans ; L-Lactate Dehydrogenase ; Oxidoreductases ; Protons ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Salvianolic acid A relieves cognitive disorder after chronic cerebral ischemia: Involvement of Drd2/Cryab/NF-κB pathway.
Autorzy :
Yang Y; School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, No.103, Wenhua Road, Shenyang 110016, PR China; Beijing Key Laboratory of Drug Target Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, PR China.
Song J; Beijing Key Laboratory of Drug Target Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, PR China. Electronic address: .
Liu N; Beijing Key Laboratory of Drug Target Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, PR China; College of Traditional Chinese Medicine, Guangdong Pharmaceutical University, 280 Waihuan East Road, Panyu District, Guangdong 510006, PR China.
Wei G; Beijing Key Laboratory of Drug Target Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, PR China; College of Traditional Chinese Medicine, Guangdong Pharmaceutical University, 280 Waihuan East Road, Panyu District, Guangdong 510006, PR China.
Liu S; Beijing Key Laboratory of Drug Target Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, PR China; College of Traditional Chinese Medicine, Guangdong Pharmaceutical University, 280 Waihuan East Road, Panyu District, Guangdong 510006, PR China.
Zhang S; Beijing Key Laboratory of Drug Target Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, PR China.
Jiang N; Beijing Key Laboratory of Drug Target Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, PR China; School of Pharmacy, Henan University, North Section of Jinming Avenue, Kaifeng 475004, Henan, PR China.
Yang H; Beijing Key Laboratory of Drug Target Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, PR China.
Du G; School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, No.103, Wenhua Road, Shenyang 110016, PR China; Beijing Key Laboratory of Drug Target Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, PR China. Electronic address: .
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Źródło :
Pharmacological research [Pharmacol Res] 2022 Jan; Vol. 175, pp. 105989. Date of Electronic Publication: 2021 Nov 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Ischemia/*drug therapy
Caffeic Acids/*therapeutic use
Cognitive Dysfunction/*drug therapy
Lactates/*therapeutic use
Neuroinflammatory Diseases/*drug therapy
Neuroprotective Agents/*therapeutic use
Animals ; Brain/drug effects ; Brain/metabolism ; Brain/pathology ; Brain Ischemia/metabolism ; Brain Ischemia/pathology ; Caffeic Acids/pharmacology ; Cell Hypoxia/drug effects ; Cell Line, Tumor ; Chronic Disease ; Cognitive Dysfunction/metabolism ; Cognitive Dysfunction/pathology ; Crystallins/metabolism ; Glucose/metabolism ; Humans ; Lactates/pharmacology ; Male ; Microtubule-Associated Proteins/metabolism ; NF-kappa B/metabolism ; Neuroinflammatory Diseases/metabolism ; Neuroinflammatory Diseases/pathology ; Neuroprotective Agents/pharmacology ; Rats, Wistar ; Receptors, Dopamine D2/metabolism
Czasopismo naukowe
Tytuł :
Curcumin Modulates 1,2-dibehenoyl-sn-glycero-3-phosphocholine (DBPC) Liposomes: Chitosan Oligosaccharide Lactate Influences Membrane Fluidity But Does Not Alter Phase Transition Temperature of DBPC Liposomes.
Autorzy :
Estephan M; Department of Chemistry, American University of Beirut, Beirut, Lebanon.
Kurdi RE; Department of Chemistry, American University of Beirut, Beirut, Lebanon.
Badran A; Department of Basic Sciences, University of Petra, P.O. Box 961343, Amman, Jordan.
Baydoun E; Department of Biology, American University of Beirut, Beirut, Lebanon.
Patra D; Department of Chemistry, American University of Beirut, Beirut, Lebanon. .
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Źródło :
Journal of fluorescence [J Fluoresc] 2022 Jan; Vol. 32 (1), pp. 155-163. Date of Electronic Publication: 2021 Oct 14.
Typ publikacji :
Journal Article
MeSH Terms :
Chitosan*
Curcumin*/chemistry
Curcumin*/pharmacology
Lactates*
Liposomes*
Membrane Fluidity*
Oligosaccharides*
Phase Transition*/drug effects
Phospholipids*
Transition Temperature*/drug effects
Drug Delivery Systems ; Fluorescence ; Hydrophobic and Hydrophilic Interactions ; Lipid Bilayers/chemistry ; Liquid Crystals ; Photochemical Processes
Czasopismo naukowe
Tytuł :
Prognostic utility of lactate concentrations and kinetics to predict adverse events associated with acute drug overdose.
Autorzy :
Kim SJ; Department of Emergency Medicine, Korea University Ansan Hospital, Anasn, Republic of Korea.
Cho H; Department of Emergency Medicine, Korea University Ansan Hospital, Anasn, Republic of Korea.
Ahn S; Department of Emergency Medicine, Korea University Ansan Hospital, Anasn, Republic of Korea.
Kim JY; Department of Emergency Medicine, Korea University Ansan Hospital, Anasn, Republic of Korea.
Song J; Department of Emergency Medicine, Korea University Ansan Hospital, Anasn, Republic of Korea.
Park JH; Department of Emergency Medicine, Korea University Ansan Hospital, Anasn, Republic of Korea. Electronic address: .
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Źródło :
The American journal of emergency medicine [Am J Emerg Med] 2021 Dec; Vol. 50, pp. 120-125. Date of Electronic Publication: 2021 Jul 26.
Typ publikacji :
Journal Article
MeSH Terms :
Emergency Service, Hospital*
Drug Overdose/*blood
Lactates/*blood
Adult ; Female ; Humans ; Lactates/pharmacokinetics ; Length of Stay/statistics & numerical data ; Male ; Middle Aged ; Predictive Value of Tests ; Prognosis ; Registries ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Phenyl-Lactic Acid Is an Active Ingredient in Bactericidal Supernatants of Lactobacillus crispatus.
Autorzy :
Abdul-Rahim O; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicagogrid.164971.c, Maywood, Illinois, USA.
Wu Q; School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Price TK; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicagogrid.164971.c, Maywood, Illinois, USA.
Pistone G; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicagogrid.164971.c, Maywood, Illinois, USA.
Diebel K; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicagogrid.164971.c, Maywood, Illinois, USA.
Bugni TS; School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Wolfe AJ; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicagogrid.164971.c, Maywood, Illinois, USA.
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Źródło :
Journal of bacteriology [J Bacteriol] 2021 Sep 08; Vol. 203 (19), pp. e0036021. Date of Electronic Publication: 2021 Sep 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Anti-Infective Agents/*chemistry
Anti-Infective Agents/*pharmacology
Lactates/*metabolism
Lactates/*pharmacology
Lactobacillus crispatus/*metabolism
Anti-Infective Agents/metabolism ; Bacteria/drug effects ; Candida/drug effects ; Lactates/chemistry
Czasopismo naukowe
Tytuł :
Identification of Novel Histone Deacetylase 6-Selective Inhibitors Bearing 3,3,3-Trifluorolactic Amide (TFLAM) Motif as a Zinc Binding Group.
Autorzy :
Kurohara T; SANKEN, Osaka University, Mihogaoka, Ibaraki-shi, Osaka, 567-0047, Japan.
Tanaka K; Bio Science and Engineering Laboratory, Research and Development Management Headquarters, FUJIFILM Corporation, 577, Ushijima, Kaisei-machi, Ashigarakami-gun, Kanagawa, 258-8577, Japan.
Takahashi D; Division of Biochemistry, Faculty of Pharmacy, Keio University, Tokyo, 105-0011, Japan.
Ueda S; Bio Science and Engineering Laboratory, Research and Development Management Headquarters, FUJIFILM Corporation, 577, Ushijima, Kaisei-machi, Ashigarakami-gun, Kanagawa, 258-8577, Japan.
Yamashita Y; SANKEN, Osaka University, Mihogaoka, Ibaraki-shi, Osaka, 567-0047, Japan.
Takada Y; SANKEN, Osaka University, Mihogaoka, Ibaraki-shi, Osaka, 567-0047, Japan.
Takeshima H; SANKEN, Osaka University, Mihogaoka, Ibaraki-shi, Osaka, 567-0047, Japan.
Yu S; SANKEN, Osaka University, Mihogaoka, Ibaraki-shi, Osaka, 567-0047, Japan.
Itoh Y; SANKEN, Osaka University, Mihogaoka, Ibaraki-shi, Osaka, 567-0047, Japan.
Hase K; Division of Biochemistry, Faculty of Pharmacy, Keio University, Tokyo, 105-0011, Japan.
Suzuki T; SANKEN, Osaka University, Mihogaoka, Ibaraki-shi, Osaka, 567-0047, Japan.
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Źródło :
Chembiochem : a European journal of chemical biology [Chembiochem] 2021 Nov 16; Vol. 22 (22), pp. 3158-3163. Date of Electronic Publication: 2021 Jul 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amides/*pharmacology
Histone Deacetylase 6/*antagonists & inhibitors
Histone Deacetylase Inhibitors/*pharmacology
Lactates/*pharmacology
Zinc/*pharmacology
Amides/chemistry ; Histone Deacetylase 6/metabolism ; Histone Deacetylase Inhibitors/chemistry ; Humans ; Lactates/chemistry ; Molecular Docking Simulation ; Molecular Structure ; Zinc/chemistry
Czasopismo naukowe
Tytuł :
The role of trauma scoring systems and serum lactate level in predicting prognosis in thoracic trauma.
Autorzy :
Çınar E; Department of Thoracic Surgery, Ankara City Hospital, Ankara-Turkey.
Usul E; Department of Emergency Medicine, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara-Turkey.
Demirtaş E; Department of Emergency Medicine, Dokuz Eylül Universty Faculty of Medicine, İzmir-Turkey.
Gökçe A; Department of Thoracic Surgery, Ankara City Hospital, Ankara-Turkey.
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Transliterated Title :
Torasik travmada prognoz tahmininde travma puanlama sistemelerinin rolü ve serum laktat düzeyi.
Źródło :
Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES [Ulus Travma Acil Cerrahi Derg] 2021 Nov; Vol. 27 (6), pp. 619-623.
Typ publikacji :
Journal Article
MeSH Terms :
Lactates*
Wounds and Injuries*
Humans ; Injury Severity Score ; Predictive Value of Tests ; Prognosis ; Retrospective Studies ; Trauma Severity Indices
Czasopismo naukowe
Tytuł :
Salvianolic acid A attenuates steroid resistant nephrotic syndrome through suPAR/uPAR-αvβ3 signaling Inhibition.
Autorzy :
Li X; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China.
Qi D; Department of Nephrology, Yu-Huang-Ding Hospital/Qingdao University, 264000, Yantai, Shandong, PR China. Electronic address: .
Wang MY; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China.
Ji K; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China.
Xie QL; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China.
Wang Y; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China.
Du SH; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China.
Fan HY; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Oct 28; Vol. 279, pp. 114351. Date of Electronic Publication: 2021 Jun 19.
Typ publikacji :
Journal Article
MeSH Terms :
Caffeic Acids/*pharmacology
Glucocorticoids/*pharmacology
Lactates/*pharmacology
Nephrotic Syndrome/*drug therapy
Receptors, Urokinase Plasminogen Activator/*genetics
Adult ; Caffeic Acids/isolation & purification ; Case-Control Studies ; Female ; Humans ; Lactates/isolation & purification ; Male ; Membrane Proteins/genetics ; Middle Aged ; Nephrotic Syndrome/genetics ; Nephrotic Syndrome/physiopathology ; Podocytes/drug effects ; Podocytes/metabolism ; Receptors, Glucocorticoid/genetics ; Salvia miltiorrhiza/chemistry ; Signal Transduction/drug effects ; Young Adult
SCR Disease Name :
Nephrosis, congenital
Czasopismo naukowe
Tytuł :
Danshensu attenuates cisplatin-induced nephrotoxicity through activation of Nrf2 pathway and inhibition of NF-κB.
Autorzy :
Yu C; School of Pharmacy, Binzhou Medical University, Yantai, Shandong, China. Electronic address: .
Dong H; Department of Nephrology, Binzhou Medical University Hospital, Binzhou, Shandong, China.
Wang Q; School of Pharmacy, Binzhou Medical University, Yantai, Shandong, China.
Bai J; The Second School of Clinical Medicine, Binzhou Medical University, Yantai, Shandong, China.
Li YN; School of Pharmacy, Binzhou Medical University, Yantai, Shandong, China.
Zhao JJ; School of Pharmacy, Binzhou Medical University, Yantai, Shandong, China.
Li JZ; College of Chemistry and Chemical Engineering, Yantai University, Yantai, Shandong, China.
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Oct; Vol. 142, pp. 111995. Date of Electronic Publication: 2021 Aug 19.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*toxicity
Cisplatin/*toxicity
Kidney Diseases/*prevention & control
Lactates/*pharmacology
Animals ; Blood Urea Nitrogen ; Dose-Response Relationship, Drug ; Heme Oxygenase-1/metabolism ; Kidney Diseases/chemically induced ; Lactates/administration & dosage ; Male ; Membrane Proteins/metabolism ; Mice ; Mice, Inbred C57BL ; NF-E2-Related Factor 2/metabolism ; NF-kappa B/metabolism ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Effect of L-calcium lactate, zinc lactate, and ferric sodium EDTA on the physicochemical and functional properties of liquid whole egg.
Autorzy :
Hou Y; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, P. R. China.; College of Food Science & Technology, Nanchang University, Nanchang, P. R. China.
Xu X; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, P. R. China.; College of Food Science & Technology, Nanchang University, Nanchang, P. R. China.
Hu W; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, P. R. China.; College of Food Science & Technology, Nanchang University, Nanchang, P. R. China.
Pei H; College of Food Science & Technology, Nanchang University, Nanchang, P. R. China.
Chen H; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, P. R. China.; Jiangxi-OAI Joint Research Institute, Nanchang University, Nanchang, P. R. China.
Tong P; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, P. R. China.
Gao J; College of Food Science & Technology, Nanchang University, Nanchang, P. R. China.
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Źródło :
Journal of food science [J Food Sci] 2021 Sep; Vol. 86 (9), pp. 3839-3854. Date of Electronic Publication: 2021 Aug 01.
Typ publikacji :
Journal Article
MeSH Terms :
Calcium Compounds*/pharmacology
Eggs*/analysis
Ferric Compounds*/pharmacology
Lactates*/pharmacology
Edetic Acid/pharmacology ; Food, Fortified/standards ; Humans ; Zinc/chemistry
Czasopismo naukowe
Tytuł :
Danshensu inhibits the IL-1β-induced inflammatory response in chondrocytes and osteoarthritis possibly via suppressing NF-κB signaling pathway.
Autorzy :
Xu Z; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350004, Fujian Province, People's Republic of China.; Department of Emergency Surgery, Fujian Provincial Hospital, No.134 East Street, Gulou District, Fuzhou, 350001, Fujian Province, People's Republic of China.; Fujian Provincial Key Laboratory of Emergency Medicine, Fujian Provincial Hospital, Fuzhou, 350001, Fujian, People's Republic of China.
Ke T; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350004, Fujian Province, People's Republic of China.; Department of Emergency Surgery, Fujian Provincial Hospital, No.134 East Street, Gulou District, Fuzhou, 350001, Fujian Province, People's Republic of China.
Zhang Y; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350004, Fujian Province, People's Republic of China.; Department of Emergency Surgery, Fujian Provincial Hospital, No.134 East Street, Gulou District, Fuzhou, 350001, Fujian Province, People's Republic of China.
Guo L; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350004, Fujian Province, People's Republic of China.; Department of Emergency Surgery, Fujian Provincial Hospital, No.134 East Street, Gulou District, Fuzhou, 350001, Fujian Province, People's Republic of China.
Chen F; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350004, Fujian Province, People's Republic of China. .; Department of Emergency Surgery, Fujian Provincial Hospital, No.134 East Street, Gulou District, Fuzhou, 350001, Fujian Province, People's Republic of China. .; Fujian Provincial Key Laboratory of Emergency Medicine, Fujian Provincial Hospital, Fuzhou, 350001, Fujian, People's Republic of China. .
He W; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350004, Fujian Province, People's Republic of China. .; Department of Emergency Surgery, Fujian Provincial Hospital, No.134 East Street, Gulou District, Fuzhou, 350001, Fujian Province, People's Republic of China. .; Fujian Provincial Key Laboratory of Emergency Medicine, Fujian Provincial Hospital, Fuzhou, 350001, Fujian, People's Republic of China. .
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Źródło :
Molecular medicine (Cambridge, Mass.) [Mol Med] 2021 Jul 20; Vol. 27 (1), pp. 80. Date of Electronic Publication: 2021 Jul 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chondrocytes/*drug effects
Chondrocytes/*metabolism
Interleukin-1beta/*metabolism
Lactates/*pharmacology
NF-kappa B/*metabolism
Osteoarthritis/*metabolism
Signal Transduction/*drug effects
Animals ; Biomarkers ; Cell Survival/drug effects ; Cytokines/metabolism ; Disease Models, Animal ; Disease Progression ; Disease Susceptibility ; Extracellular Matrix/metabolism ; Inflammation Mediators/metabolism ; Lactates/administration & dosage ; Lactates/chemistry ; Mice ; Osteoarthritis/drug therapy ; Osteoarthritis/etiology ; Osteoarthritis/pathology
Czasopismo naukowe
Tytuł :
Characterization of a traditional ripened cheese, Kurdish Kope: Lipolysis, lactate metabolism, the release profile of volatile compounds, and correlations with sensory characteristics.
Autorzy :
Esmaeilzadeh P; Department of Food Science and Technology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Ehsani MR; Department of Food Science and Technology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Mizani M; Department of Food Science and Technology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Givianrad MH; Department of Chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran.
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Źródło :
Journal of food science [J Food Sci] 2021 Aug; Vol. 86 (8), pp. 3303-3321. Date of Electronic Publication: 2021 Jul 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cheese*/analysis
Cheese*/standards
Lactates*/metabolism
Lipolysis*
Taste*
Volatile Organic Compounds*/analysis
Flavoring Agents
Czasopismo naukowe
Tytuł :
Salvianolic acid A alleviated inflammatory response mediated by microglia through inhibiting the activation of TLR2/4 in acute cerebral ischemia-reperfusion.
Autorzy :
Ling Y; Animal Experimental Research Center, Academy of Traditional Chinese Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, People's Republic of China.
Jin L; Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, People's Republic of China.
Ma Q; Animal Experimental Research Center, Academy of Traditional Chinese Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, People's Republic of China.
Huang Y; Animal Experimental Research Center, Academy of Traditional Chinese Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, People's Republic of China.
Yang Q; Zhejiang Academy of Traditional Chinese Medicine, Hangzhou, 310007, People's Republic of China.
Chen M; Animal Experimental Research Center, Academy of Traditional Chinese Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, People's Republic of China. Electronic address: .
Shou Q; Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, People's Republic of China; Department of Pharmacy, Zhejiang Chinese Medical University, Hangzhou 310053, People's Republic of China. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2021 Jul; Vol. 87, pp. 153569. Date of Electronic Publication: 2021 Apr 15.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Ischemia/*drug therapy
Caffeic Acids/*pharmacology
Lactates/*pharmacology
Microglia/*drug effects
Reperfusion Injury/*drug therapy
Toll-Like Receptor 2/*metabolism
Toll-Like Receptor 4/*metabolism
Animals ; Brain Ischemia/pathology ; Caffeic Acids/therapeutic use ; Infarction, Middle Cerebral Artery ; Inflammation/metabolism ; Lactates/therapeutic use ; Male ; Microglia/metabolism ; Myeloid Differentiation Factor 88/metabolism ; NF-kappa B/metabolism ; Rats ; Signal Transduction/drug effects ; Toll-Like Receptor 2/antagonists & inhibitors ; Toll-Like Receptor 2/genetics ; Toll-Like Receptor 4/antagonists & inhibitors ; Toll-Like Receptor 4/genetics
Czasopismo naukowe
Tytuł :
Studies on the Catalytic Properties of Crude Freeze-Dried Preparations of Yarrowia lipolytica Extracellular Lipases for Geranyl Ester Derivative Synthesis.
Autorzy :
Jasińska K; Department of Chemistry, Institute of Food Sciences, Warsaw University of Life Sciences-SGGW, 159c Nowoursynowska St., 02-776 Warsaw, Poland.
Zieniuk B; Department of Chemistry, Institute of Food Sciences, Warsaw University of Life Sciences-SGGW, 159c Nowoursynowska St., 02-776 Warsaw, Poland.
Nowak D; Department of Food Engineering and Process Management, Institute of Food Sciences, Warsaw University of Life Sciences-SGGW, 159c Nowoursynowska St., 02-776 Warsaw, Poland.
Fabiszewska A; Department of Chemistry, Institute of Food Sciences, Warsaw University of Life Sciences-SGGW, 159c Nowoursynowska St., 02-776 Warsaw, Poland.
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Źródło :
Biomolecules [Biomolecules] 2021 Jun 04; Vol. 11 (6). Date of Electronic Publication: 2021 Jun 04.
Typ publikacji :
Journal Article
MeSH Terms :
Acyclic Monoterpenes/*metabolism
Extracellular Fluid/*enzymology
Lactates/*metabolism
Lipase/*metabolism
Yarrowia/*enzymology
Acyclic Monoterpenes/chemical synthesis ; Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/metabolism ; Antioxidants/chemical synthesis ; Antioxidants/metabolism ; Catalysis ; Esters ; Freeze Drying/methods ; Lactates/chemical synthesis ; Lipase/chemistry ; Microbial Sensitivity Tests/methods ; Yarrowia/chemistry
Czasopismo naukowe
Tytuł :
miR-3189-targeted GLUT3 repression by HDAC2 knockdown inhibits glioblastoma tumorigenesis through regulating glucose metabolism and proliferation.
Autorzy :
Kwak, Sungmin (AUTHOR)
Park, Seung-Ho (AUTHOR)
Kim, Sung-Hak (AUTHOR)
Sung, Gi-Jun (AUTHOR)
Song, Ji-Hye (AUTHOR)
Jeong, Ji-Hoon (AUTHOR)
Kim, Hyunhee (AUTHOR)
Ha, Chang Hoon (AUTHOR)
Kim, Seong Who (AUTHOR)
Choi, Kyung-Chul (AUTHOR)
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Źródło :
Journal of Experimental & Clinical Cancer Research (17569966). 3/8/2022, Vol. 41 Issue 1, p1-18. 18p.
Czasopismo naukowe
Tytuł :
Validation of a Gas Chromatography-Mass Spectrometry Method for the Measurement of the Redox State Metabolic Ratios Lactate/Pyruvate and β-Hydroxybutyrate/Acetoacetate in Biological Samples.
Autorzy :
Wijngaard R; Service of Biochemistry and Molecular Genetics, Hospital Clinic Universitari, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Carrer de Villarroel 170, 08036 Barcelona, Spain.
Perramón M; Service of Biochemistry and Molecular Genetics, Hospital Clinic Universitari, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Carrer de Villarroel 170, 08036 Barcelona, Spain.
Parra-Robert M; Service of Biochemistry and Molecular Genetics, Hospital Clinic Universitari, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Carrer de Villarroel 170, 08036 Barcelona, Spain.
Hidalgo S; Service of Biochemistry and Molecular Genetics, Hospital Clinic Universitari, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Carrer de Villarroel 170, 08036 Barcelona, Spain.
Butrico G; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA.
Morales-Ruiz M; Service of Biochemistry and Molecular Genetics, Hospital Clinic Universitari, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Carrer de Villarroel 170, 08036 Barcelona, Spain.; Department of Biomedicine, University of Barcelona, 08036 Barcelona, Spain.; Working Group for the Biochemical Assessment of Hepatic Disease-SEQCML, 08036 Barcelona, Spain.
Zeng M; School of Biotechnology and Health Sciences, Wuyi University, 99 Yingbing Middle Rd., Jiangmen 529020, China.
Casals E; School of Biotechnology and Health Sciences, Wuyi University, 99 Yingbing Middle Rd., Jiangmen 529020, China.
Jiménez W; Service of Biochemistry and Molecular Genetics, Hospital Clinic Universitari, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Carrer de Villarroel 170, 08036 Barcelona, Spain.; Department of Biomedicine, University of Barcelona, 08036 Barcelona, Spain.
Fernández-Varo G; Service of Biochemistry and Molecular Genetics, Hospital Clinic Universitari, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Carrer de Villarroel 170, 08036 Barcelona, Spain.; Department of Biomedicine, University of Barcelona, 08036 Barcelona, Spain.
Shulman GI; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA.
Cline GW; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA.
Casals G; Service of Biochemistry and Molecular Genetics, Hospital Clinic Universitari, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Carrer de Villarroel 170, 08036 Barcelona, Spain.; Working Group for the Biochemical Assessment of Hepatic Disease-SEQCML, 08036 Barcelona, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 30; Vol. 22 (9). Date of Electronic Publication: 2021 Apr 30.
Typ publikacji :
Journal Article; Validation Study
MeSH Terms :
Gas Chromatography-Mass Spectrometry*/methods
3-Hydroxybutyric Acid/*metabolism
Acetoacetates/*metabolism
Lactates/*metabolism
Pyruvates/*metabolism
3-Hydroxybutyric Acid/analysis ; 3-Hydroxybutyric Acid/blood ; Acetoacetates/analysis ; Acetoacetates/blood ; Animals ; Female ; Hep G2 Cells ; Humans ; Lactates/analysis ; Lactates/blood ; Limit of Detection ; Liver/chemistry ; Liver/metabolism ; Oxidation-Reduction ; Pyruvates/analysis ; Pyruvates/blood ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Noninvasive method for determination of immobilized protein A.
Autorzy :
Mravljak R; Department of Chemical Engineering and Technical Safety, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana SI-1000, Slovenia.
Stantič M; Department of Chemical Engineering and Technical Safety, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana SI-1000, Slovenia.
Bizjak O; Department of Chemical Engineering and Technical Safety, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana SI-1000, Slovenia.
Podgornik A; Department of Chemical Engineering and Technical Safety, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana SI-1000, Slovenia; COBIK, Mirce 21, 5270 Ajdovščina, Slovenia. Electronic address: .
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Źródło :
Journal of chromatography. A [J Chromatogr A] 2022 May 24; Vol. 1671, pp. 462976. Date of Electronic Publication: 2022 Mar 15.
Typ publikacji :
Journal Article
MeSH Terms :
Chromatography*/methods
Staphylococcal Protein A*
Enzymes, Immobilized/chemistry ; Hydrogen-Ion Concentration ; Lactates ; Sepharose/chemistry
Czasopismo naukowe
Tytuł :
Energy metabolism as the target of 3-phenyllactic acid against Rhizopus oryzae.
Autorzy :
Fan W; School of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, Gansu Province 730050, PR China. Electronic address: .
Li B; School of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, Gansu Province 730050, PR China.
Du N; School of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, Gansu Province 730050, PR China.
Hui T; School of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, Gansu Province 730050, PR China.
Cao Y; School of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, Gansu Province 730050, PR China.
Li X; School of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, Gansu Province 730050, PR China.
Ren H; School of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, Gansu Province 730050, PR China.
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Źródło :
International journal of food microbiology [Int J Food Microbiol] 2022 May 16; Vol. 369, pp. 109606. Date of Electronic Publication: 2022 Mar 01.
Typ publikacji :
Journal Article
MeSH Terms :
Energy Metabolism*
Rhizopus oryzae*
Glycolysis ; Lactates/metabolism ; Rhizopus/metabolism
Czasopismo naukowe
Tytuł :
Melanoma cells with diverse invasive potential differentially induce the activation of normal human fibroblasts.
Autorzy :
Mazurkiewicz J; Department of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, Joliot-Curie 14a, 50-383, Wrocław, Poland. .
Simiczyjew A; Department of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, Joliot-Curie 14a, 50-383, Wrocław, Poland.
Dratkiewicz E; Department of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, Joliot-Curie 14a, 50-383, Wrocław, Poland.
Pietraszek-Gremplewicz K; Department of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, Joliot-Curie 14a, 50-383, Wrocław, Poland.
Majkowski M; Faculty of Biotechnology, University of Wroclaw, Joliot-Curie 14a, 50-383, Wrocław, Poland.
Kot M; Department of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, Joliot-Curie 14a, 50-383, Wrocław, Poland.
Ziętek M; Department of Oncology and Division of Surgical Oncology, Wroclaw Medical University, Plac Hirszfelda 12, 53-413, Wrocław, Poland.; Wroclaw Comprehensive Cancer Center, Plac Hirszfelda 12, 53-413, Wrocław, Poland.
Matkowski R; Department of Oncology and Division of Surgical Oncology, Wroclaw Medical University, Plac Hirszfelda 12, 53-413, Wrocław, Poland.; Wroclaw Comprehensive Cancer Center, Plac Hirszfelda 12, 53-413, Wrocław, Poland.
Nowak D; Department of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, Joliot-Curie 14a, 50-383, Wrocław, Poland.
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Źródło :
Cell communication and signaling : CCS [Cell Commun Signal] 2022 May 10; Vol. 20 (1), pp. 63. Date of Electronic Publication: 2022 May 10.
Typ publikacji :
Journal Article; Video-Audio Media
MeSH Terms :
Interleukin-6*/metabolism
Melanoma*/pathology
Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Female ; Fibroblasts/metabolism ; Gelatin/metabolism ; Humans ; Lactates/metabolism ; Placenta Growth Factor/metabolism ; Proteomics ; Tumor Microenvironment
Czasopismo naukowe

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