Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""LEPTIN"" wg kryterium: Temat


Tytuł :
Leptin suppresses development of GLP-1 inputs to the paraventricular nucleus of the hypothalamus.
Autorzy :
Biddinger JE; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, United States.
Lazarenko RM; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, United States.
Scott MM; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, United States.
Simerly R; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, United States.
Pokaż więcej
Źródło :
ELife [Elife] 2020 Nov 18; Vol. 9. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Glucagon-Like Peptide 1/*metabolism
Leptin/*metabolism
Paraventricular Hypothalamic Nucleus/*growth & development
Paraventricular Hypothalamic Nucleus/*metabolism
Animals ; Mice ; Mice, Transgenic ; Neurons/metabolism ; Proglucagon/metabolism ; Receptors, Leptin/genetics ; Receptors, Leptin/metabolism ; Solitary Nucleus/metabolism
Czasopismo naukowe
Tytuł :
CNS Regulation of Glucose Homeostasis: Role of the Leptin-Melanocortin System.
Autorzy :
da Silva AA; Department of Physiology and Biophysics, Mississippi Center for Obesity Research, and Cardiovascular-Renal Research Center, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS, 39216-4505, USA. .
do Carmo JM; Department of Physiology and Biophysics, Mississippi Center for Obesity Research, and Cardiovascular-Renal Research Center, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS, 39216-4505, USA.
Hall JE; Department of Physiology and Biophysics, Mississippi Center for Obesity Research, and Cardiovascular-Renal Research Center, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS, 39216-4505, USA.
Pokaż więcej
Źródło :
Current diabetes reports [Curr Diab Rep] 2020 May 26; Vol. 20 (7), pp. 29. Date of Electronic Publication: 2020 May 26.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Insulin*
Leptin*
Animals ; Glucose ; Homeostasis ; Humans ; Melanocortins ; Receptors, Leptin
Czasopismo naukowe
Tytuł :
Photoperiod Affects Leptin Action on the Choroid Plexus in Ewes Challenged with Lipopolysaccharide-Study on the mRNA Level.
Autorzy :
Szczepkowska A; Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, 10-748 Olsztyn, Poland.
Kowalewska M; Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, 10-748 Olsztyn, Poland.
Krawczyńska A; The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, 05-110 Jabłonna, Poland.
Herman AP; The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, 05-110 Jabłonna, Poland.
Skipor J; Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, 10-748 Olsztyn, Poland.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 15; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 15.
Typ publikacji :
Journal Article
MeSH Terms :
Photoperiod*
Choroid Plexus/*metabolism
Inflammasomes/*metabolism
Leptin/*blood
Animals ; Chemokine CCL2/genetics ; Chemokine CCL2/metabolism ; Choroid Plexus/drug effects ; Female ; Inflammasomes/genetics ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Interleukin-6/genetics ; Interleukin-6/metabolism ; Lipopolysaccharides/toxicity ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, Interleukin/genetics ; Receptors, Interleukin/metabolism ; Receptors, Leptin/genetics ; Receptors, Leptin/metabolism ; Sheep ; Toll-Like Receptor 4/genetics ; Toll-Like Receptor 4/metabolism
Czasopismo naukowe
Tytuł :
Effects of gut microbiota on leptin expression and body weight are lessened by high-fat diet in mice.
Autorzy :
Yao H; Laboratory of Nutrition and Development, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing100045, People's Republic of China.
Fan C; Laboratory of Nutrition and Development, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing100045, People's Republic of China.
Fan X; Laboratory of Nutrition and Development, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing100045, People's Republic of China.
Lu Y; Department of Child Health Care Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing100045, People's Republic of China.
Wang Y; Laboratory of Nutrition and Development, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing100045, People's Republic of China.
Wang R; Laboratory of Nutrition and Development, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing100045, People's Republic of China.
Tang T; Laboratory of Nutrition and Development, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing100045, People's Republic of China.
Qi K; Laboratory of Nutrition and Development, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing100045, People's Republic of China.
Pokaż więcej
Źródło :
The British journal of nutrition [Br J Nutr] 2020 Aug 28; Vol. 124 (4), pp. 396-406. Date of Electronic Publication: 2020 Mar 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Body Weight*
Diet, High-Fat/*adverse effects
Gastrointestinal Microbiome/*physiology
Leptin/*metabolism
Obesity/*metabolism
Adipose Tissue/metabolism ; Adiposity/genetics ; Animals ; Disease Models, Animal ; Hypothalamus/metabolism ; Liver/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Obesity/etiology ; Pro-Opiomelanocortin/metabolism ; Receptors, Leptin/metabolism
Czasopismo naukowe
Tytuł :
Effects of leptin on HPG axis and reproductive function in male rat in simulated altitude of 5500 m hypoxia environment.
Autorzy :
Liu X; Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005, China. Electronic address: .
Liu S; Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005, China. Electronic address: .
Xu C; Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005, China; Center of Environmental and Health Sciences, Chinese Academy of Medical Sciences, Beijing, China. Electronic address: .
Pokaż więcej
Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Aug 13; Vol. 529 (1), pp. 104-111. Date of Electronic Publication: 2020 Jun 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Altitude*
Altitude Sickness/*physiopathology
Hypoxia/*physiopathology
Leptin/*physiology
Reproduction/*physiology
Animals ; Apoptosis ; Disease Models, Animal ; Humans ; Hypothalamo-Hypophyseal System/physiopathology ; Male ; Rats ; Rats, Sprague-Dawley ; Receptors, Leptin/physiology ; Sperm Count ; Sperm Motility ; Spermatogenesis/physiology ; Testis/pathology ; Testis/physiopathology
Czasopismo naukowe
Tytuł :
Detection of polymorphisms in the bovine leptin receptor gene affects fat deposition in two Chinese beef cattle breeds.
Autorzy :
Raza SHA; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, PR China; National Beef Cattle Improvement Center, Northwest A&F University, 712100 Yangling, Shaanxi, PR China. Electronic address: .
Liu GY; Poyang Lake Eco-economy Research Center, Jiujiang University, Jiujiang, Jiangxi Province 332005, PR China.
Zhou L; State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, Qinghai Province 810016, PR China.
Gui LS; State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, Qinghai Province 810016, PR China.
Khan R; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, PR China.
Jinmeng Y; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, PR China.
Chugang M; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, PR China.
Schreurs NM; Animal Science, School of Agriculture and Environment, Massey University, Palmerston North, New Zealand.
Ji R; Utah State University, School of Animal Dairy and Veterinary Sciences, Logan, UT, 84322, USA.
Zan L; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, PR China; National Beef Cattle Improvement Center, Northwest A&F University, 712100 Yangling, Shaanxi, PR China. Electronic address: .
Pokaż więcej
Źródło :
Gene [Gene] 2020 Oct 20; Vol. 758, pp. 144957. Date of Electronic Publication: 2020 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Body Fat Distribution*
Adiposity/*genetics
Receptors, Leptin/*genetics
Receptors, Leptin/*metabolism
Animals ; Cattle ; Gene Frequency/genetics ; Genetic Association Studies ; Genotype ; Leptin/metabolism ; Polymorphism, Single Nucleotide/genetics
Czasopismo naukowe
Tytuł :
HIV Protease Inhibitor Ritonavir Impairs Endothelial Function Via Reduction in Adipose Mass and Endothelial Leptin Receptor-Dependent Increases in NADPH Oxidase 1 (Nox1), C-C Chemokine Receptor Type 5 (CCR5), and Inflammation.
Autorzy :
Bruder-Nascimento T; Vascular Biology Center Medical College of Georgia at Augusta University Augusta GA.; Division of Endocrinology Department of Pediatrics Center for Pediatric Research in Obesity and Metabolism (CPROM) Pittsburg PA.; Vascular Medicine Institute (VMI) University of Pittsburgh PA.
Kress TC; Vascular Biology Center Medical College of Georgia at Augusta University Augusta GA.
Kennard S; Vascular Biology Center Medical College of Georgia at Augusta University Augusta GA.
Belin de Chantemèle EJ; Vascular Biology Center Medical College of Georgia at Augusta University Augusta GA.; Division of Cardiology Department of Medicine Medical College of Georgia at Augusta University Augusta GA.
Pokaż więcej
Źródło :
Journal of the American Heart Association [J Am Heart Assoc] 2020 Oct 20; Vol. 9 (19), pp. e018074. Date of Electronic Publication: 2020 Oct 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipose Tissue*/drug effects
Adipose Tissue*/metabolism
Cardiovascular Diseases*/etiology
Cardiovascular Diseases*/metabolism
Cardiovascular Diseases*/prevention & control
Endothelial Cells*/drug effects
Endothelial Cells*/metabolism
NADPH Oxidase 1/*metabolism
Receptors, CCR5/*metabolism
Receptors, Leptin/*metabolism
Ritonavir/*pharmacokinetics
Animals ; Body Weight/drug effects ; HIV Protease Inhibitors/pharmacokinetics ; Inflammation/metabolism ; Leptin/metabolism ; Mice ; Oxidative Stress/drug effects ; Signal Transduction
Czasopismo naukowe
Tytuł :
Leptin Induces Hypertension Acting on Transient Receptor Potential Melastatin 7 Channel in the Carotid Body.
Autorzy :
Shin MK; From the Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (M.-K.S., C.G., B.H.Y.Y., L.J.K., J.S.K.S., V.Y.P.).
Eraso CC; Unidad Médico-Quirúrgica de Enfermedades Respiratorias, Instituto de Biomedicina de Sevilla (IBiS), Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Hospital Universitario Virgen del Rocío/Universidad de Sevilla, Spain (C.C.E.).
Mu YP; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (Y.-P.M., X.-R.L., Z.-J.W.).
Gu C; From the Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (M.-K.S., C.G., B.H.Y.Y., L.J.K., J.S.K.S., V.Y.P.).
Yeung BHY; From the Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (M.-K.S., C.G., B.H.Y.Y., L.J.K., J.S.K.S., V.Y.P.).
Kim LJ; From the Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (M.-K.S., C.G., B.H.Y.Y., L.J.K., J.S.K.S., V.Y.P.).; Departamento de Psicobiologia, Universidade Federal de São Paulo, Brazil (L.J.K.).
Liu XR; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (Y.-P.M., X.-R.L., Z.-J.W.).
Wu ZJ; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (Y.-P.M., X.-R.L., Z.-J.W.).
Paudel O; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (O.P., L.E.P., M.S.).
Pichard LE; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (O.P., L.E.P., M.S.).
Shirahata M; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (O.P., L.E.P., M.S.).
Tang WY
Sham JSK; From the Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (M.-K.S., C.G., B.H.Y.Y., L.J.K., J.S.K.S., V.Y.P.).
Polotsky VY; From the Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (M.-K.S., C.G., B.H.Y.Y., L.J.K., J.S.K.S., V.Y.P.).
Pokaż więcej
Źródło :
Circulation research [Circ Res] 2019 Nov 08; Vol. 125 (11), pp. 989-1002. Date of Electronic Publication: 2019 Sep 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Pressure*/drug effects
Leptin*
Carotid Body/*metabolism
Hypertension/*chemically induced
Receptors, Leptin/*metabolism
TRPM Cation Channels/*metabolism
Animals ; Antihypertensive Agents/pharmacology ; Carotid Body/drug effects ; Carotid Body/physiopathology ; Denervation ; Disease Models, Animal ; Hypertension/metabolism ; Hypertension/physiopathology ; Hypertension/prevention & control ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Obesity/complications ; Receptors, Leptin/deficiency ; Receptors, Leptin/genetics ; Signal Transduction ; TRPM Cation Channels/antagonists & inhibitors ; TRPM Cation Channels/genetics
Czasopismo naukowe
Tytuł :
Association study of rs7799039, rs1137101 and rs8192678 gene variants with disease susceptibility/severity and corresponding LEP, LEPR and PGC1A gene expression in multiple sclerosis.
Autorzy :
Kolić I; 'Vinča' Institute of Nuclear Sciences - National Institute of thе Republic of Serbia, Laboratory for Radiobiology and Molecular Genetics, University of Belgrade, Mike Petrovića Alasa 12-14, Belgrade, Serbia.
Stojković L; 'Vinča' Institute of Nuclear Sciences - National Institute of thе Republic of Serbia, Laboratory for Radiobiology and Molecular Genetics, University of Belgrade, Mike Petrovića Alasa 12-14, Belgrade, Serbia. Electronic address: .
Stankovic A; 'Vinča' Institute of Nuclear Sciences - National Institute of thе Republic of Serbia, Laboratory for Radiobiology and Molecular Genetics, University of Belgrade, Mike Petrovića Alasa 12-14, Belgrade, Serbia.
Stefanović M; 'Vinča' Institute of Nuclear Sciences - National Institute of thе Republic of Serbia, Laboratory for Radiobiology and Molecular Genetics, University of Belgrade, Mike Petrovića Alasa 12-14, Belgrade, Serbia.
Dinčić E; Military Medical Academy, Clinic for Neurology, Crnotravska 17, Belgrade, Serbia.
Zivkovic M; 'Vinča' Institute of Nuclear Sciences - National Institute of thе Republic of Serbia, Laboratory for Radiobiology and Molecular Genetics, University of Belgrade, Mike Petrovića Alasa 12-14, Belgrade, Serbia.
Pokaż więcej
Źródło :
Gene [Gene] 2021 Mar 30; Vol. 774, pp. 145422. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Journal Article
MeSH Terms :
Polymorphism, Single Nucleotide*
Leptin/*genetics
Multiple Sclerosis/*genetics
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/*genetics
Receptors, Leptin/*genetics
Adult ; Case-Control Studies ; Female ; Gene Expression ; Genetic Association Studies ; Genetic Predisposition to Disease ; Humans ; Leptin/blood ; Leukocytes, Mononuclear ; Male ; Middle Aged ; Patient Acuity ; Real-Time Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Stratified layer analysis reveals intrinsic leptin stimulates cryptal mesenchymal cells for controlling mucosal inflammation.
Autorzy :
Matsumura S; Department of Innovative Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan.; Department of Mucosal Immunology, The University of Tokyo Distinguished Professor Unit, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan.; Department of Pediatrics, Juntendo University Faculty of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.
Kurashima Y; Department of Innovative Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan. .; Department of Mucosal Immunology, The University of Tokyo Distinguished Professor Unit, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan. .; International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan. .; Division of Gastroenterology, Department of Medicine, CU-UCSD Center for Mucosal Immunology, Allergy and Vaccines (CU-UCSD cMAV), University of California, San Diego, CA, 92093-0956, USA. .; Division of Comparative Pathology and Medicine, Department of Pathology, University of California San Diego, San Diego, CA, 92093-0956, USA. .
Murasaki S; Department of Mucosal Immunology, The University of Tokyo Distinguished Professor Unit, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan.
Morimoto M; Department of Innovative Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan.
Arai F; Department of Mucosal Immunology, The University of Tokyo Distinguished Professor Unit, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan.
Saito Y; Department of Innovative Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan.
Katayama N; Department of Mucosal Immunology, The University of Tokyo Distinguished Professor Unit, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan.
Kim D; Department of Mucosal Immunology, The University of Tokyo Distinguished Professor Unit, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan.
Inagaki Y; Center for Matrix Biology and Medicine, Graduate School of Medicine, Tokai University, Kanagawa, Japan.
Kudo T; Department of Pediatrics, Juntendo University Faculty of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.
Ernst PB; Division of Gastroenterology, Department of Medicine, CU-UCSD Center for Mucosal Immunology, Allergy and Vaccines (CU-UCSD cMAV), University of California, San Diego, CA, 92093-0956, USA.; Division of Comparative Pathology and Medicine, Department of Pathology, University of California San Diego, San Diego, CA, 92093-0956, USA.; Center for Veterinary Sciences and Comparative Medicine, University of California, San Diego, CA, 92093-0956, USA.
Shimizu T; Department of Pediatrics, Juntendo University Faculty of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.
Kiyono H; Department of Mucosal Immunology, The University of Tokyo Distinguished Professor Unit, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan.; International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan.; Division of Gastroenterology, Department of Medicine, CU-UCSD Center for Mucosal Immunology, Allergy and Vaccines (CU-UCSD cMAV), University of California, San Diego, CA, 92093-0956, USA.
Pokaż więcej
Źródło :
Scientific reports [Sci Rep] 2020 Oct 27; Vol. 10 (1), pp. 18351. Date of Electronic Publication: 2020 Oct 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Inflammation/*metabolism
Intestinal Mucosa/*metabolism
Leptin/*metabolism
Mesenchymal Stem Cells/*metabolism
Animals ; Cellular Microenvironment ; Colon/metabolism ; Homeostasis ; Intestinal Mucosa/cytology ; Male ; Mice ; Mice, Inbred C57BL ; Receptors, Leptin/metabolism ; Transcriptome ; Wnt Proteins/metabolism
Czasopismo naukowe
Tytuł :
C-Peptide and leptin system in dichorionic, small and appropriate for gestational age twins-possible link to metabolic programming?
Autorzy :
Lewandowski KC; Department of Endocrinology and Metabolic Diseases, Polish Mothers' Memorial Hospital-Research Institute, Lodz, Poland.; Medical University of Lodz, Department of Endocrinology and Metabolic Diseases, Lodz, Poland.
Biesiada L; Department of Obstetrics and Gynecology, Polish Mother's Memorial Hospital-Research Institute, Lodz, Poland.
Grzesiak M; Department of Perinatology, Obstetrics and Gynecology, Polish Mother's Memorial Hospital-Research Institute, Lodz, Poland.
Sakowicz A; Medical University of Lodz, Department of Medical Biotechnology, Lodz, Poland. .
Pokaż więcej
Źródło :
Nutrition & diabetes [Nutr Diabetes] 2020 Aug 10; Vol. 10 (1), pp. 29. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Twins*
Blood Glucose/*analysis
C-Peptide/*blood
Infant, Small for Gestational Age/*blood
Receptors, Leptin/*blood
Body Weight ; Diabetes Mellitus, Type 2/epidemiology ; Female ; Fetal Growth Retardation/blood ; Fetal Growth Retardation/epidemiology ; Fetus/metabolism ; Gestational Age ; Glucose Intolerance/epidemiology ; Humans ; Infant, Newborn ; Insulin/blood ; Insulin Resistance ; Leptin/blood ; Male ; Placenta/metabolism ; Pregnancy
Czasopismo naukowe
Tytuł :
Leptin Signaling Affects Survival and Chemoresistance of Estrogen Receptor Negative Breast Cancer.
Autorzy :
Lipsey CC; Microbiology, Biochemistry, and Immunology, GEBS, Morehouse School of Medicine, Atlanta, GA 30310, USA.; Laboratory of Cell Biology, Center for Cancer Research, NCI, National Institutes of Health, Bethesda, MD 20892, USA.
Harbuzariu A; Microbiology, Biochemistry, and Immunology, GEBS, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Robey RW; Laboratory of Cell Biology, Center for Cancer Research, NCI, National Institutes of Health, Bethesda, MD 20892, USA.
Huff LM; Laboratory of Cell Biology, Center for Cancer Research, NCI, National Institutes of Health, Bethesda, MD 20892, USA.
Gottesman MM; Laboratory of Cell Biology, Center for Cancer Research, NCI, National Institutes of Health, Bethesda, MD 20892, USA.
Gonzalez-Perez RR; Microbiology, Biochemistry, and Immunology, GEBS, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 May 27; Vol. 21 (11). Date of Electronic Publication: 2020 May 27.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Resistance, Neoplasm*
Signal Transduction*
Breast Neoplasms/*metabolism
Leptin/*metabolism
Breast Neoplasms/drug therapy ; Breast Neoplasms/genetics ; Cell Line ; Cell Line, Tumor ; Cyclin-Dependent Kinase 8/genetics ; Cyclin-Dependent Kinase 8/metabolism ; Female ; Humans ; Immunoglobulin J Recombination Signal Sequence-Binding Protein/genetics ; Immunoglobulin J Recombination Signal Sequence-Binding Protein/metabolism ; Nanog Homeobox Protein/genetics ; Nanog Homeobox Protein/metabolism ; Receptors, Estrogen/genetics ; Receptors, Leptin/genetics ; Receptors, Leptin/metabolism ; Survival Analysis
Czasopismo naukowe
Tytuł :
Leptin reduces in vitro cementoblast mineralization and survival as well as induces PGE2 release by ERK1/2 commitment.
Autorzy :
Ruiz-Heiland G; Department of Orthodontics, University of Giessen, Schlangenzahl 14, 35392, Giessen, Germany. .
Yong JW; Department of Orthodontics, University of Giessen, Schlangenzahl 14, 35392, Giessen, Germany.
von Bremen J; Department of Orthodontics, University of Giessen, Schlangenzahl 14, 35392, Giessen, Germany.
Ruf S; Department of Orthodontics, University of Giessen, Schlangenzahl 14, 35392, Giessen, Germany.
Pokaż więcej
Źródło :
Clinical oral investigations [Clin Oral Investig] 2021 Apr; Vol. 25 (4), pp. 1933-1944. Date of Electronic Publication: 2020 Aug 20.
Typ publikacji :
Journal Article
MeSH Terms :
Dental Cementum*
Leptin*
Apoptosis ; Dinoprostone ; Humans ; MAP Kinase Signaling System ; Overweight
Czasopismo naukowe
Tytuł :
Identification of a novel leptin receptor (LEPR) variant and proof of functional relevance directing treatment decisions in patients with morbid obesity.
Autorzy :
Voigtmann F; Center of Pediatric Research Leipzig, University Hospital for Children & Adolescents, Medical Faculty, University of Leipzig, Germany.
Wolf P; Institute of Biochemistry, Faculty of Life Sciences, Pharmacy and Psychology, University of Leipzig, Germany.
Landgraf K; Center of Pediatric Research Leipzig, University Hospital for Children & Adolescents, Medical Faculty, University of Leipzig, Germany.
Stein R; Center of Pediatric Research Leipzig, University Hospital for Children & Adolescents, Medical Faculty, University of Leipzig, Germany; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Germany.
Kratzsch J; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnosis, University Medical Center Leipzig, Medical Faculty, University of Leipzig, Germany.
Schmitz S; Department of Chemistry and Center for Structural Biology, Vanderbilt University, TN, USA.
Abou Jamra R; Institute of Human Genetics, University Medical Center Leipzig, Medical Faculty, University of Leipzig, Germany.
Blüher M; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Germany; Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig, Germany.
Meiler J; Department of Chemistry and Center for Structural Biology, Vanderbilt University, TN, USA; Institute of Drug Discovery, Medical Faculty, University of Leipzig, Germany.
Beck-Sickinger AG; Institute of Biochemistry, Faculty of Life Sciences, Pharmacy and Psychology, University of Leipzig, Germany.
Kiess W; Center of Pediatric Research Leipzig, University Hospital for Children & Adolescents, Medical Faculty, University of Leipzig, Germany.
Körner A; Center of Pediatric Research Leipzig, University Hospital for Children & Adolescents, Medical Faculty, University of Leipzig, Germany. Electronic address: .
Pokaż więcej
Źródło :
Metabolism: clinical and experimental [Metabolism] 2021 Mar; Vol. 116, pp. 154438. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Obesity, Morbid/*genetics
Obesity, Morbid/*therapy
Pediatric Obesity/*genetics
Pediatric Obesity/*therapy
Receptors, Leptin/*genetics
Child ; Decision Making ; Female ; HEK293 Cells ; Humans ; Infant ; Models, Molecular ; Mutation, Missense ; Obesity, Morbid/diagnosis ; Pediatric Obesity/diagnosis ; Pedigree ; Polymorphism, Single Nucleotide ; Protein Conformation ; Receptors, Leptin/chemistry
Czasopismo naukowe
Tytuł :
A White Grape Juice Extract Reduces Fat Accumulation through the Modulation of Ghrelin and Leptin Expression in an In Vivo Model of Overfed Zebrafish.
Autorzy :
Montalbano G; Zebrafish Neuromorphology Lab, Department of Veterinary Sciences, University of Messina, 98168 Messina, Italy.
Maugeri A; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98122 Messina, Italy.
Guerrera MC; Zebrafish Neuromorphology Lab, Department of Veterinary Sciences, University of Messina, 98168 Messina, Italy.
Miceli N; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98122 Messina, Italy.
Navarra M; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98122 Messina, Italy.
Barreca D; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98122 Messina, Italy.
Cirmi S; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98122 Messina, Italy.; Department of Pharmacy-Drug Sciences, University of Bari 'Aldo Moro', 70125 Bari, Italy.
Germanà A; Zebrafish Neuromorphology Lab, Department of Veterinary Sciences, University of Messina, 98168 Messina, Italy.
Pokaż więcej
Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Feb 20; Vol. 26 (4). Date of Electronic Publication: 2021 Feb 20.
Typ publikacji :
Journal Article
MeSH Terms :
Adipocytes/*drug effects
Fats/*antagonists & inhibitors
Ghrelin/*antagonists & inhibitors
Leptin/*antagonists & inhibitors
Plant Extracts/*pharmacology
Vitis/*chemistry
Animals ; Disease Models, Animal ; Fats/metabolism ; Fruit and Vegetable Juices/analysis ; Ghrelin/genetics ; Ghrelin/metabolism ; Leptin/genetics ; Leptin/metabolism ; Molecular Structure ; Obesity/drug therapy ; Obesity/metabolism ; Plant Extracts/administration & dosage ; Plant Extracts/chemistry ; RNA, Messenger/antagonists & inhibitors ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Zebrafish
Czasopismo naukowe
Tytuł :
The effect of postpartum period back massage on serum ghrelin, leptin, adiponectin and visfatin levels.
Autorzy :
Goker A; Manisa Celal Bayar University Faculty of Medicine Department of Obstetrics and Gynecology Manisa, Turkey. Electronic address: .
Kosova F; Manisa Celal Bayar University Vocation School of Health Services, Medical Biochemistry Manisa, Turkey.
Koken Durgun S; Manisa Celal Bayar University School of Health Department of Midwifery Manisa, Turkey.
Demirtas Z; Manisa Celal Bayar University School of Health Department of Midwifery Manisa, Turkey.
Pokaż więcej
Źródło :
Complementary therapies in clinical practice [Complement Ther Clin Pract] 2021 Feb; Vol. 42, pp. 101284. Date of Electronic Publication: 2020 Dec 11.
Typ publikacji :
Journal Article
MeSH Terms :
Adiponectin*
Leptin*
Female ; Ghrelin ; Humans ; Massage ; Nicotinamide Phosphoribosyltransferase ; Postpartum Period ; Pregnancy
Czasopismo naukowe
Tytuł :
Evaluation of the Impact of Cisplatin on Variances in the Expression Pattern of Leptin-Related Genes in Endometrial Cancer Cells.
Autorzy :
Dąbruś D; Faculty of Health Science, Public Higher Medical Professional School in Opole, 45-060 Opole, Poland.
Kiełbasiński R; Department of Obstetrics and Gynaecology ward, Health Center in Mikołów, 43-190 Mikołów, Poland.
Grabarek BO; Department of Histology, Cytophysiology, and Embryology, Faculty of Medicine in Zabrze, the University of Technology in Katowice, 40-055 Katowice, Poland.; Department of Clinical Trials, Maria Sklodowska-Curie National Research Institute of Oncology Krakow Branch, 31-115 Kraków, Poland.
Boroń D; Department of Histology, Cytophysiology, and Embryology, Faculty of Medicine in Zabrze, the University of Technology in Katowice, 40-055 Katowice, Poland.; Department of Clinical Trials, Maria Sklodowska-Curie National Research Institute of Oncology Krakow Branch, 31-115 Kraków, Poland.; Department of Gynecology and Obstetrics with Gynecologic Oncology, Ludwik Rydygier Memorial Specialized Hospital, 31-826 Kraków, Poland.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Jun 10; Vol. 21 (11). Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Cisplatin/*pharmacology
Endometrial Neoplasms/*drug therapy
Endometrial Neoplasms/*genetics
Leptin/*genetics
Antineoplastic Agents/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Caspases/metabolism ; Cell Line, Tumor ; Cell Size/drug effects ; Cisplatin/administration & dosage ; Dose-Response Relationship, Drug ; Endometrial Neoplasms/pathology ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Janus Kinase 2/genetics ; Janus Kinase 2/metabolism ; Leptin/administration & dosage ; Leptin/metabolism ; Leptin/pharmacology ; RNA Interference ; Receptors, Leptin/genetics ; STAT3 Transcription Factor/genetics ; STAT3 Transcription Factor/metabolism
Czasopismo naukowe
Tytuł :
Acid sphingomyelinase downregulation alleviates vascular endothelial leptin resistance in rats.
Autorzy :
Cai BB; Department of Clinical Pharmacy, School of Preclinical Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Lu YN; Department of Clinical Pharmacy, School of Preclinical Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Xu M; Department of Clinical Pharmacy, School of Preclinical Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China. .
Pokaż więcej
Źródło :
Acta pharmacologica Sinica [Acta Pharmacol Sin] 2020 May; Vol. 41 (5), pp. 650-660. Date of Electronic Publication: 2019 Dec 17.
Typ publikacji :
Journal Article
MeSH Terms :
Down-Regulation*/drug effects
Endothelial Cells/*metabolism
Leptin/*metabolism
Sphingomyelin Phosphodiesterase/*metabolism
Amitriptyline/pharmacology ; Animals ; Biocatalysis ; Cells, Cultured ; Disease Models, Animal ; Endothelial Cells/drug effects ; Enzyme Inhibitors/pharmacology ; Imipramine/pharmacology ; Leptin/antagonists & inhibitors ; Male ; Palmitic Acid/pharmacology ; Rats ; Rats, Sprague-Dawley ; Receptors, Leptin/deficiency ; Receptors, Leptin/metabolism ; Sphingomyelin Phosphodiesterase/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Leptin and cardiovascular health in high body mass index.
Autorzy :
Liew CH; School of Medicine, National University of Ireland Galway, Galway, Ireland. .; National Institute for Prevention and Cardiovascular Health, Galway, Ireland. .; School of Medicine, Trinity College Dublin, Dublin, Ireland. .
Sim WH; Department of Medicine, University Hospital Limerick, Limerick, Ireland.
Low EZ; Department of Geriatric Medicine, Letterkenny University Hospital, Letterkenny, Ireland.
Chan BCM; Department of General Surgery, Our Lady of Lourdes Hospital, Drogheda, Ireland.
Pokaż więcej
Źródło :
Irish journal of medical science [Ir J Med Sci] 2021 Feb; Vol. 190 (1), pp. 441-442. Date of Electronic Publication: 2020 Jul 02.
Typ publikacji :
Letter; Comment
MeSH Terms :
Cardiovascular Diseases*
Leptin*
Body Mass Index ; Humans ; Risk Factors
Opinia redakcyjna
Tytuł :
Chronic CNS-mediated cardiometabolic actions of leptin: potential role of sex differences.
Autorzy :
da Silva AA; Department of Physiology and Biophysics, Mississippi Center for Obesity Research, Cardiovascular-Renal Research Center, University of Mississippi Medical Center, Jackson, Mississippi.
Pinkerton MA; Department of Physiology and Biophysics, Mississippi Center for Obesity Research, Cardiovascular-Renal Research Center, University of Mississippi Medical Center, Jackson, Mississippi.
Spradley FT; Department of Surgery, University of Mississippi Medical Center, Jackson, Mississippi.
Palei AC; Department of Surgery, University of Mississippi Medical Center, Jackson, Mississippi.
Hall JE; Department of Physiology and Biophysics, Mississippi Center for Obesity Research, Cardiovascular-Renal Research Center, University of Mississippi Medical Center, Jackson, Mississippi.
do Carmo JM; Department of Physiology and Biophysics, Mississippi Center for Obesity Research, Cardiovascular-Renal Research Center, University of Mississippi Medical Center, Jackson, Mississippi.
Pokaż więcej
Źródło :
American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2021 Feb 01; Vol. 320 (2), pp. R173-R181. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Appetite/*drug effects
Blood Pressure/*drug effects
Glucose/*metabolism
Heart Rate/*drug effects
Homeostasis/*drug effects
Leptin/*pharmacology
Animals ; Diabetes Mellitus, Experimental ; Female ; Injections, Intraventricular ; Leptin/administration & dosage ; Male ; Rats ; Rats, Sprague-Dawley ; Sex Factors
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies