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Tytuł :
YAP promotes self-renewal of gastric cancer cells by inhibiting expression of L-PTGDS and PTGDR2.
Autorzy :
Bie Q; Department of Laboratory Medicine, Affiliated Hospital of Jining Medical University, Jining Medical University, 89 Guhuai Road, Jining, 272000, Shandong, People's Republic of China.; Institute of Forensic Medicine and Laboratory Medicine, Jining Medical University, Jining, Shandong, People's Republic of China.
Li X; Department of Laboratory Medicine, Affiliated Hospital of Jining Medical University, Jining Medical University, 89 Guhuai Road, Jining, 272000, Shandong, People's Republic of China.
Liu S; Department of General Surgery, Affiliated Hospital of Jining Medical University, Jining, Shandong, People's Republic of China.
Yang X; Department of Laboratory Medicine, Affiliated Hospital of Jining Medical University, Jining Medical University, 89 Guhuai Road, Jining, 272000, Shandong, People's Republic of China.
Qian Z; Department of Laboratory Medicine, Affiliated Hospital of Jining Medical University, Jining Medical University, 89 Guhuai Road, Jining, 272000, Shandong, People's Republic of China.
Zhao R; Department of Laboratory Medicine, Affiliated Hospital of Jining Medical University, Jining Medical University, 89 Guhuai Road, Jining, 272000, Shandong, People's Republic of China.
Zhang X; Department of Central Laboratory, Affiliated Hospital of Jining Medical University, Jining, Shandong, People's Republic of China.
Zhang B; Department of Laboratory Medicine, Affiliated Hospital of Jining Medical University, Jining Medical University, 89 Guhuai Road, Jining, 272000, Shandong, People's Republic of China. .; Institute of Forensic Medicine and Laboratory Medicine, Jining Medical University, Jining, Shandong, People's Republic of China. .
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Źródło :
International journal of clinical oncology [Int J Clin Oncol] 2020 Dec; Vol. 25 (12), pp. 2055-2065. Date of Electronic Publication: 2020 Aug 26.
Typ publikacji :
Journal Article
MeSH Terms :
Adaptor Proteins, Signal Transducing/*genetics
Intramolecular Oxidoreductases/*genetics
Lipocalins/*genetics
Receptors, Immunologic/*genetics
Receptors, Prostaglandin/*genetics
Stomach Neoplasms/*pathology
Transcription Factors/*genetics
Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Cell Line, Tumor ; Cell Self Renewal ; Gene Expression Regulation, Neoplastic ; Humans ; Intramolecular Oxidoreductases/metabolism ; Lipocalins/metabolism ; Male ; Mice, Inbred BALB C ; Neoplastic Stem Cells/pathology ; Receptors, Immunologic/metabolism ; Receptors, Prostaglandin/metabolism ; Stomach Neoplasms/genetics ; Stomach Neoplasms/metabolism ; Transcription Factors/metabolism ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
A lipocalin mediates unidirectional heme biomineralization in malaria parasites.
Autorzy :
Matz JM; Malaria Biochemistry Laboratory, The Francis Crick Institute, NW1 1AT London, United Kingdom; .; Department of Molecular Parasitology, Institute of Biology, Humboldt University, 10115 Berlin, Germany.
Drepper B; Department of Molecular Parasitology, Institute of Biology, Humboldt University, 10115 Berlin, Germany.
Blum TB; Laboratory of Nanoscale Biology, Division of Biology and Chemistry, Paul Scherrer Institute, 5232 Villigen, Switzerland.
van Genderen E; Laboratory of Nanoscale Biology, Division of Biology and Chemistry, Paul Scherrer Institute, 5232 Villigen, Switzerland.
Burrell A; Electron Microscopy Science Technology Platform, The Francis Crick Institute, NW1 1AT London, United Kingdom.
Martin P; Department of Molecular Parasitology, Institute of Biology, Humboldt University, 10115 Berlin, Germany.
Stach T; Department of Molecular Parasitology, Institute of Biology, Humboldt University, 10115 Berlin, Germany.
Collinson LM; Electron Microscopy Science Technology Platform, The Francis Crick Institute, NW1 1AT London, United Kingdom.
Abrahams JP; Laboratory of Nanoscale Biology, Division of Biology and Chemistry, Paul Scherrer Institute, 5232 Villigen, Switzerland.; Center for Cellular Imaging and NanoAnalytics, Biozentrum, University of Basel, 4051 Basel, Switzerland.; Institute of Biology, Leiden University, 2311 EZ Leiden, The Netherlands.
Matuschewski K; Department of Molecular Parasitology, Institute of Biology, Humboldt University, 10115 Berlin, Germany.
Blackman MJ; Malaria Biochemistry Laboratory, The Francis Crick Institute, NW1 1AT London, United Kingdom.; Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, WC1E 7HT London, United Kingdom.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jul 14; Vol. 117 (28), pp. 16546-16556. Date of Electronic Publication: 2020 Jun 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Heme/*metabolism
Lipocalins/*metabolism
Malaria/*parasitology
Plasmodium berghei/*metabolism
Plasmodium falciparum/*metabolism
Protozoan Proteins/*metabolism
Amino Acid Sequence ; Animals ; Hemeproteins/genetics ; Hemeproteins/metabolism ; Humans ; Lipocalins/chemistry ; Lipocalins/genetics ; Malaria/metabolism ; Mice ; Plasmodium berghei/chemistry ; Plasmodium berghei/genetics ; Plasmodium falciparum/chemistry ; Plasmodium falciparum/genetics ; Protozoan Proteins/chemistry ; Protozoan Proteins/genetics
Czasopismo naukowe
Tytuł :
Selection, preparation and characterization of scFv against human lipocalin 6 by phage display technology.
Autorzy :
Chen J; Department of Forensic Biology, Henan University of Science and Technology, Luoyang, 471023, China. Electronic address: .
Zhao Y; CITIC Heavy Industries Co., Ltd, Luoyang, 471003, China.
Feng W; Department of Forensic Biology, Henan University of Science and Technology, Luoyang, 471023, China.
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Źródło :
Protein expression and purification [Protein Expr Purif] 2020 Jul; Vol. 171, pp. 105627. Date of Electronic Publication: 2020 Mar 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lipocalins*/chemistry
Lipocalins*/immunology
Peptide Library*
Single-Chain Antibodies*/chemistry
Single-Chain Antibodies*/genetics
Single-Chain Antibodies*/immunology
Animals ; Female ; Humans ; Male ; Mice ; Mice, Inbred BALB C
Czasopismo naukowe
Tytuł :
Role of Lipocalin-Type Prostaglandin D Synthase in Experimental Osteoarthritis.
Autorzy :
Najar M; University of Montreal Hospital Research Center and University of Montreal, Montreal, Quebec, Canada.
Ouhaddi Y; University of Montreal Hospital Research Center and University of Montreal, Montreal, Quebec, Canada.
Paré F; University of Montreal Hospital Research Center and University of Montreal, Montreal, Quebec, Canada.
Lussier B; University of Montreal, Saint-Hyacinthe, Quebec, Canada.
Urade Y; University of Tokyo, Tokyo, Japan.
Kapoor M; The Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada.
Pelletier JP; University of Montreal Hospital Research Center and University of Montreal, Montreal, Quebec, Canada.
Martel-Pelletier J; University of Montreal Hospital Research Center and University of Montreal, Montreal, Quebec, Canada.
Benderdour M; Sacré-Coeur Hospital, University of Montreal, Montreal, Quebec, Canada.
Fahmi H; University of Montreal Hospital Research Center and University of Montreal, Montreal, Quebec, Canada.
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Źródło :
Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2020 Sep; Vol. 72 (9), pp. 1524-1533. Date of Electronic Publication: 2020 Jul 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arthritis, Experimental/*genetics
Cartilage, Articular/*pathology
Chondrocytes/*metabolism
Intramolecular Oxidoreductases/*genetics
Lipocalins/*genetics
Osteoarthritis/*genetics
ADAMTS5 Protein/metabolism ; Animals ; Arthritis, Experimental/diagnostic imaging ; Arthritis, Experimental/metabolism ; Arthritis, Experimental/pathology ; Bone and Bones/diagnostic imaging ; Cartilage, Articular/metabolism ; Interleukin-1alpha/pharmacology ; Intramolecular Oxidoreductases/metabolism ; Lipocalins/metabolism ; Matrix Metalloproteinase 13/metabolism ; Menisci, Tibial/surgery ; Mice ; Mice, Knockout ; Osteoarthritis/diagnostic imaging ; Osteoarthritis/pathology ; Prostaglandin D2/metabolism ; Proteoglycans/drug effects ; Proteoglycans/metabolism ; Stifle/diagnostic imaging ; Stifle/metabolism ; Stifle/pathology ; X-Ray Microtomography
Czasopismo naukowe
Tytuł :
Neutrophil gelatinase-associated lipocalin is an early marker of renal damage in lower urinary tract obstruction in rats.
Autorzy :
Karabay E; Department of Urology. University of Health Sciences. Istanbul Training and Research Hospital. Istanbul. Turkey.
Yucetas U; Department of Urology. University of Health Sciences. Istanbul Training and Research Hospital. Istanbul. Turkey.
Aytac Ates H; Department of Urology. University of Health Sciences. Istanbul Training and Research Hospital. Istanbul. Turkey.
Behzatoglu K; Department of Pathology. University of Health Sciences. Istanbul Training and Research Hospital. Istanbul. Turkey.
Yucetas E; Department of Biochemistry. University of Health Sciences. Haseki Training and Research Hospital. Istanbul. Turkey.
Karsiyakali N; Department of Urology. University of Health Sciences. Istanbul Training and Research Hospital. Istanbul. Turkey.
Kadihasanoglu M; Department of Urology. University of Health Sciences. Istanbul Training and Research Hospital. Istanbul. Turkey.
Erkan E; Department of Urology. University of Health Sciences. Istanbul Training and Research Hospital. Istanbul. Turkey.
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Transliterated Title :
NGAL es un marcador precoz de daño renal en la obstrucción del tracto urinario inferior en ratas.
Źródło :
Archivos espanoles de urologia [Arch Esp Urol] 2020 Jul; Vol. 73 (6), pp. 554-560.
Typ publikacji :
Journal Article
MeSH Terms :
Acute Kidney Injury*
Lipocalins*
Acute-Phase Proteins ; Animals ; Biomarkers ; Creatinine ; Humans ; Kidney ; Lipocalin-2 ; Male ; Proto-Oncogene Proteins ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
[Frequency of occurrence and risk factors for acute kidney injury after radical cystectomy].
Autorzy :
Tarasenko AI; FGAOU VO I.M. Sechenov First Moscow State Medical University, Moscow, Russia.; FGBOU VO Bashkir State Medical University of the Ministry of Health of the Russian Federation, Ufa, Russia.; Clinic of FGBOU VO Bashkir State Medical University of the Ministry of Health of the Russian Federation, Ufa, Russia.
Alekseev AV; FGAOU VO I.M. Sechenov First Moscow State Medical University, Moscow, Russia.; FGBOU VO Bashkir State Medical University of the Ministry of Health of the Russian Federation, Ufa, Russia.; Clinic of FGBOU VO Bashkir State Medical University of the Ministry of Health of the Russian Federation, Ufa, Russia.
Kabirov IR; FGAOU VO I.M. Sechenov First Moscow State Medical University, Moscow, Russia.; FGBOU VO Bashkir State Medical University of the Ministry of Health of the Russian Federation, Ufa, Russia.; Clinic of FGBOU VO Bashkir State Medical University of the Ministry of Health of the Russian Federation, Ufa, Russia.
Urmantsev MF; FGAOU VO I.M. Sechenov First Moscow State Medical University, Moscow, Russia.; FGBOU VO Bashkir State Medical University of the Ministry of Health of the Russian Federation, Ufa, Russia.; Clinic of FGBOU VO Bashkir State Medical University of the Ministry of Health of the Russian Federation, Ufa, Russia.
Abdrakhimov RV; FGAOU VO I.M. Sechenov First Moscow State Medical University, Moscow, Russia.; FGBOU VO Bashkir State Medical University of the Ministry of Health of the Russian Federation, Ufa, Russia.; Clinic of FGBOU VO Bashkir State Medical University of the Ministry of Health of the Russian Federation, Ufa, Russia.
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Źródło :
Urologiia (Moscow, Russia : 1999) [Urologiia] 2020 Jun (3), pp. 34-38.
Typ publikacji :
Journal Article
MeSH Terms :
Acute Kidney Injury*
Lipocalins*
Acute-Phase Proteins ; Biomarkers ; Creatinine ; Cystectomy ; Humans ; Lipocalin-2 ; Prospective Studies ; Proto-Oncogene Proteins ; Risk Factors
Czasopismo naukowe
Tytuł :
Potential synergistic effects of novel hematopoietic prostaglandin D synthase inhibitor TAS-205 and different types of anti-allergic medicine on nasal obstruction in a Guinea pig model of experimental allergic rhinitis.
Autorzy :
Aoyagi H; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co. Ltd, 3 Okubo, Tsukuba, Ibaraki, 300-2611, Japan; Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Miyagi, Japan. Electronic address: .
Kajiwara D; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co. Ltd, 3 Okubo, Tsukuba, Ibaraki, 300-2611, Japan.
Tsunekuni K; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co. Ltd, 3 Okubo, Tsukuba, Ibaraki, 300-2611, Japan.
Tanaka K; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co. Ltd, 3 Okubo, Tsukuba, Ibaraki, 300-2611, Japan.
Miyoshi K; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co. Ltd, 3 Okubo, Tsukuba, Ibaraki, 300-2611, Japan.
Hirasawa N; Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Miyagi, Japan.
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2020 May 15; Vol. 875, pp. 173030. Date of Electronic Publication: 2020 Feb 19.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Allergic Agents/*pharmacology
Enzyme Inhibitors/*pharmacology
Intramolecular Oxidoreductases/*antagonists & inhibitors
Lipocalins/*antagonists & inhibitors
Morpholines/*pharmacology
Nasal Obstruction/*drug therapy
Piperidines/*pharmacology
Pyrroles/*pharmacology
Rhinitis, Allergic/*drug therapy
Acetates/pharmacology ; Acetates/therapeutic use ; Animals ; Anti-Allergic Agents/therapeutic use ; Cell Line ; Cyclopropanes/pharmacology ; Cyclopropanes/therapeutic use ; Disease Models, Animal ; Drug Synergism ; Drug Therapy, Combination/methods ; Enzyme Inhibitors/therapeutic use ; Guinea Pigs ; Humans ; Intramolecular Oxidoreductases/metabolism ; Lipocalins/metabolism ; Male ; Morpholines/therapeutic use ; Nasal Mucosa/drug effects ; Nasal Mucosa/immunology ; Nasal Obstruction/immunology ; Ovalbumin/administration & dosage ; Ovalbumin/immunology ; Piperidines/therapeutic use ; Prostaglandin D2/metabolism ; Pyrroles/therapeutic use ; Quality of Life ; Quinolines/pharmacology ; Quinolines/therapeutic use ; Rats ; Rhinitis, Allergic/complications ; Rhinitis, Allergic/immunology ; Sulfides/pharmacology ; Sulfides/therapeutic use ; Terfenadine/analogs & derivatives ; Terfenadine/pharmacology ; Terfenadine/therapeutic use
Czasopismo naukowe
Tytuł :
Biological variation in kidney injury and kidney function biomarkers among farmers in Lamphun province, Thailand.
Autorzy :
Mueangkhiao P; Department of Forensic Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Siviroj P; Department of Community Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Sapbamrer R; Department of Community Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Khacha-Ananda S; Department of Forensic Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Lungkaphin A; Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Seesen M; Department of Community Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Jaikwang P; Department of Forensic Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Wunnapuk K; Department of Forensic Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. .
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Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2020 Apr; Vol. 27 (11), pp. 12386-12394. Date of Electronic Publication: 2020 Jan 28.
Typ publikacji :
Journal Article
MeSH Terms :
Acute-Phase Proteins*
Lipocalins*
Biomarkers ; Creatinine ; Cross-Sectional Studies ; Farmers ; Humans ; Proto-Oncogene Proteins ; Thailand
Czasopismo naukowe
Tytuł :
Procalcitonin, C-reactive protein, neutrophil gelatinase-associated lipocalin, resistin and the APTT waveform for the early diagnosis of serious bacterial infection and prediction of outcome in critically ill children.
Autorzy :
Nielsen, Maryke J. (AUTHOR)
Baines, Paul (AUTHOR)
Jennings, Rebecca (AUTHOR)
Siner, Sarah (AUTHOR)
Kolamunnage-Dona, Ruwanthi (AUTHOR)
Newland, Paul (AUTHOR)
Peak, Matthew (AUTHOR)
Chesters, Christine (AUTHOR)
Jeffers, Graham (AUTHOR)
Downey, Colin (AUTHOR)
Broughton, Caroline (AUTHOR)
McColl, Lynsey (AUTHOR)
Preston, Jennifer (AUTHOR)
McKeever, Anthony (AUTHOR)
Paulus, Stephane (AUTHOR)
Cunliffe, Nigel (AUTHOR)
Carrol, Enitan D. (AUTHOR)
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Źródło :
PLoS ONE. 2/5/2021, Vol. 16 Issue 2, p1-15. 15p.
Czasopismo naukowe
Tytuł :
Ectopic expression of human apolipoprotein D in Arabidopsis plants lacking chloroplastic lipocalin partially rescues sensitivity to drought and oxidative stress.
Autorzy :
Henri P; Aix-Marseille Université, CEA, CNRS, UMR 7265, Institut Biosciences et Biotechnologies d'Aix-Marseille, Plant Protein Protection Laboratory, CEA/Cadarache, F-13108, Saint-Paul-lez-Durance, France.
Rumeau D; Aix-Marseille Université, CEA, CNRS, UMR 7265, Institut Biosciences et Biotechnologies d'Aix-Marseille, Plant Protein Protection Laboratory, CEA/Cadarache, F-13108, Saint-Paul-lez-Durance, France. Electronic address: .
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Źródło :
Plant physiology and biochemistry : PPB [Plant Physiol Biochem] 2021 Jan; Vol. 158, pp. 265-274. Date of Electronic Publication: 2020 Nov 16.
Typ publikacji :
Journal Article
MeSH Terms :
Dehydration*
Oxidative Stress*
Apolipoproteins D/*biosynthesis
Arabidopsis/*metabolism
Lipocalins/*chemistry
Arabidopsis/genetics ; Chloroplasts/chemistry ; Droughts ; Ectopic Gene Expression ; Humans ; Plants, Genetically Modified
Czasopismo naukowe
Tytuł :
What makes an allergen an allergen? Formyl-peptidyl receptor 3 and lipocalins: At the crossroads of T H 2 induction.
Autorzy :
Rhyner C; Swiss Institute of Asthma and Allergy Research (SIAF), Davos, Switzerland; Davos BioSciences, Davos, Switzerland. Electronic address: .
Brüggen MC; Faculty of Medicine, University of Zurich, Zurich, Switzerland; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland; Department of Dermatology, Hochgebirgsklinik Davos, Zurich, Switzerland.
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Źródło :
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2020 Feb; Vol. 145 (2), pp. 494-495. Date of Electronic Publication: 2019 Nov 24.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Allergens*
Lipocalins*
Dendritic Cells/immunology ; Humans ; Peptides ; Receptors, Formyl Peptide ; Th2 Cells/immunology
Opinia redakcyjna
Tytuł :
Prostaglandin D2 synthase modulates macrophage activity and accumulation in injured peripheral nerves.
Autorzy :
Forese MG; Division of Neuroscience, INSPE, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Pellegatta M; Division of Neuroscience, INSPE, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Canevazzi P; Division of Neuroscience, INSPE, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Gullotta GS; Division of Neuroscience, INSPE, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Podini P; Division of Neuroscience, INSPE, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Rivellini C; Division of Neuroscience, INSPE, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Previtali SC; Division of Neuroscience, INSPE, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Bacigaluppi M; Division of Neuroscience, INSPE, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Quattrini A; Division of Neuroscience, INSPE, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Taveggia C; Division of Neuroscience, INSPE, IRCCS San Raffaele Scientific Institute, Milan, Italy.
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Źródło :
Glia [Glia] 2020 Jan; Vol. 68 (1), pp. 95-110. Date of Electronic Publication: 2019 Sep 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Intramolecular Oxidoreductases/*biosynthesis
Lipocalins/*biosynthesis
Macrophage Activation/*physiology
Nerve Regeneration/*physiology
Sciatic Neuropathy/*enzymology
Animals ; Female ; Intramolecular Oxidoreductases/genetics ; Lipocalins/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Peripheral Nerve Injuries/genetics ; Peripheral Nerve Injuries/metabolism ; Peripheral Nerve Injuries/pathology ; Sciatic Neuropathy/genetics ; Sciatic Neuropathy/pathology
Czasopismo naukowe
Tytuł :
FluoroCalins: engineered lipocalins with novel binding functions fused to a fluorescent protein for applications in biomolecular imaging and detection.
Autorzy :
Eggenstein E; Lehrstuhl für Biologische Chemie, Technische Universität München, Emil-Erlenmeyer-Forum 5, 85354 Freising, Germany.
Richter A; Lehrstuhl für Biologische Chemie, Technische Universität München, Emil-Erlenmeyer-Forum 5, 85354 Freising, Germany.
Skerra A; Lehrstuhl für Biologische Chemie, Technische Universität München, Emil-Erlenmeyer-Forum 5, 85354 Freising, Germany.
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Źródło :
Protein engineering, design & selection : PEDS [Protein Eng Des Sel] 2019 Dec 31; Vol. 32 (6), pp. 289-296.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Engineering*
Green Fluorescent Proteins/*genetics
Lipocalins/*genetics
Lipocalins/*metabolism
Molecular Imaging/*methods
Recombinant Fusion Proteins/*genetics
Recombinant Fusion Proteins/*metabolism
Lipocalins/chemistry ; Models, Molecular ; Protein Conformation ; Recombinant Fusion Proteins/chemistry
Czasopismo naukowe
Tytuł :
Development of hypoallergenic variants of the major horse allergen Equ c 1 for immunotherapy by rational structure based engineering.
Autorzy :
Haka J; Desentum Ltd, Kivipylväänkuja 5, 02940, Espoo, Finland.
Niemi MH; Department of Chemistry, University of Eastern Finland, PO Box 111, 80101, Joensuu, Finland.
Mattila P; Desentum Ltd, Kivipylväänkuja 5, 02940, Espoo, Finland.
Jänis J; Department of Chemistry, University of Eastern Finland, PO Box 111, 80101, Joensuu, Finland.
Takkinen K; VTT Technical Research Centre of Finland, PO Box 1000, 02044, Espoo, Finland.
Rouvinen J; Department of Chemistry, University of Eastern Finland, PO Box 111, 80101, Joensuu, Finland. .
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Źródło :
Scientific reports [Sci Rep] 2019 Dec 27; Vol. 9 (1), pp. 20148. Date of Electronic Publication: 2019 Dec 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Desensitization, Immunologic*
Allergens/*immunology
Antigenic Variation/*immunology
Hypersensitivity/*immunology
Hypersensitivity/*therapy
Lipocalins/*immunology
Allergens/chemistry ; Allergens/genetics ; Animals ; Genetic Variation ; Histamine Release ; Horses ; Humans ; Hypersensitivity/metabolism ; Immunoglobulin E/immunology ; Lipocalins/chemistry ; Lipocalins/genetics ; Mass Spectrometry ; Models, Molecular ; Molecular Conformation ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Activation of six lipocalins genes' transcription under PCB18 stress in OsTIL-silenced Oryza sativa L.
Autorzy :
Hao D; University of Science and Technology Beijing School of Chemistry and Biological Engineering, Department of Biological Science and Engineering, 30 Xueyuan Road, Haidian District, Beijing, 100083 China.
Wang H; University of Science and Technology Beijing School of Chemistry and Biological Engineering, Department of Biological Science and Engineering, 30 Xueyuan Road, Haidian District, Beijing, 100083 China. Electronic address: .
Niu L; University of Science and Technology Beijing School of Chemistry and Biological Engineering, 30 Xueyuan Road, Haidian District, Beijing, 100083 China.
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2020 Nov; Vol. 204, pp. 111063. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article
MeSH Terms :
Environmental Pollutants/*toxicity
Lipocalins/*genetics
Oryza/*drug effects
Oxidative Stress/*drug effects
Polychlorinated Biphenyls/*toxicity
Transcriptional Activation/*drug effects
Gene Expression Regulation, Plant ; Gene Silencing ; Genes, Plant ; Oryza/genetics ; Oryza/growth & development ; Oxidative Stress/genetics
Czasopismo naukowe
Tytuł :
L-type prostaglandin D synthase regulates the trafficking of the PGD 2 DP1 receptor by interacting with the GTPase Rab4.
Autorzy :
Binda C; Département de Médecine, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada.; Institut de Pharmacologie de Sherbrooke, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada.
Génier S; Département de Médecine, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada.; Institut de Pharmacologie de Sherbrooke, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada.
Degrandmaison J; Département de Médecine, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada.; Institut de Pharmacologie de Sherbrooke, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada.
Picard S; Département de Médecine, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada.; Institut de Pharmacologie de Sherbrooke, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada.; Département de Pharmacologie-Physiologie, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada.
Fréchette L; Département de Médecine, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada.; Institut de Pharmacologie de Sherbrooke, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada.
Jean S; Département d'Anatomie et de Biologie Cellulaire, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada.
Marsault E; Institut de Pharmacologie de Sherbrooke, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada.; Département de Pharmacologie-Physiologie, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada.
Parent JL; Département de Médecine, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada .; Institut de Pharmacologie de Sherbrooke, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada.
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2019 Nov 08; Vol. 294 (45), pp. 16865-16883. Date of Electronic Publication: 2019 Oct 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Intramolecular Oxidoreductases/*metabolism
Lipocalins/*metabolism
Prostaglandin D2/*metabolism
Receptors, Prostaglandin/*metabolism
rab4 GTP-Binding Proteins/*metabolism
Enzyme Activation ; HeLa Cells ; Humans ; Intramolecular Oxidoreductases/chemistry ; Lipocalins/chemistry ; Protein Binding ; Protein Domains ; Protein Transport
Czasopismo naukowe
Tytuł :
Delay in hepatocyte proliferation and prostaglandin D2 synthase expression for cholestasis due to endotoxin during partial hepatectomy in rats.
Autorzy :
Wakasa Y; Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori 036‑8562, Japan.
Kimura N; Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori 036‑8562, Japan.
Yamada T; Department of Biochemistry and Genome Biology, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori 036‑8562, Japan.
Shimizu T; Department of Biochemistry and Genome Biology, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori 036‑8562, Japan.
Hakamada K; Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori 036‑8562, Japan.
Tsuchida S; Department of Biochemistry and Genome Biology, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori 036‑8562, Japan.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2019 Nov; Vol. 20 (5), pp. 4367-4375. Date of Electronic Publication: 2019 Sep 13.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation*
Cholestasis/*etiology
Cholestasis/*metabolism
Endotoxins/*adverse effects
Hepatocytes/*metabolism
Intramolecular Oxidoreductases/*genetics
Lipocalins/*genetics
Animals ; Bile Acids and Salts/blood ; Bile Acids and Salts/metabolism ; Bilirubin/blood ; Biomarkers ; Cell Proliferation ; Chemokine CXCL9/genetics ; Chemokine CXCL9/metabolism ; Disease Models, Animal ; Hepatectomy ; Immunohistochemistry ; Intramolecular Oxidoreductases/metabolism ; Kupffer Cells/metabolism ; Lipocalins/metabolism ; Male ; RNA, Messenger/genetics ; Rats
Czasopismo naukowe
Tytuł :
Association between the rs2590498 polymorphism of Odorant Binding Protein (OBPIIa) gene and olfactory performance in healthy subjects.
Autorzy :
Sollai G; Department of Biomedical Sciences, Sect. of Physiology, University of Cagliari, Italy. Electronic address: .
Melis M; Department of Biomedical Sciences, Sect. of Physiology, University of Cagliari, Italy.
Magri S; Department of Medical Sciences and Public Health, University of Cagliari, Presidio Policlinico of Monserrato, Cagliari, Italy.
Usai P; Department of Medical Sciences and Public Health, University of Cagliari, Presidio Policlinico of Monserrato, Cagliari, Italy.
Hummel T; Smell and Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany.
Tomassini Barbarossa I; Department of Biomedical Sciences, Sect. of Physiology, University of Cagliari, Italy.
Crnjar R; Department of Biomedical Sciences, Sect. of Physiology, University of Cagliari, Italy.
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Źródło :
Behavioural brain research [Behav Brain Res] 2019 Oct 17; Vol. 372, pp. 112030. Date of Electronic Publication: 2019 Jun 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lipocalins/*genetics
Smell/*genetics
Adult ; Alleles ; Female ; Gene Frequency/genetics ; Healthy Volunteers ; Humans ; Lipocalins/metabolism ; Male ; Middle Aged ; Odorants ; Olfaction Disorders/genetics ; Olfaction Disorders/physiopathology ; Olfactory Receptor Neurons/physiology ; Polymorphism, Single Nucleotide/genetics ; Receptors, Odorant/genetics ; Sensory Thresholds/physiology
Czasopismo naukowe

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