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Tytuł :
Blocking PDGF-CC signaling ameliorates multiple sclerosis-like neuroinflammation by inhibiting disruption of the blood-brain barrier.
Autorzy :
Zeitelhofer M; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden. .
Adzemovic MZ; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden.; Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Moessinger C; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden.
Stefanitsch C; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden.
Strell C; Department of Immunology, Genetics and Pathology, Uppsala University, 75185, Uppsala, Sweden.
Muhl L; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden.
Brundin L; Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Fredriksson L; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden.
Olsson T; Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Eriksson U; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden.
Nilsson I; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden. .
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Źródło :
Scientific reports [Sci Rep] 2020 Dec 24; Vol. 10 (1), pp. 22383. Date of Electronic Publication: 2020 Dec 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Neutralizing/*pharmacology
Blood-Brain Barrier/*immunology
Encephalomyelitis, Autoimmune, Experimental/*immunology
Lymphokines/*antagonists & inhibitors
Multiple Sclerosis/*immunology
Platelet-Derived Growth Factor/*antagonists & inhibitors
Signal Transduction/*drug effects
Animals ; Blood-Brain Barrier/pathology ; Down-Regulation/drug effects ; Down-Regulation/immunology ; Encephalomyelitis, Autoimmune, Experimental/drug therapy ; Encephalomyelitis, Autoimmune, Experimental/genetics ; Encephalomyelitis, Autoimmune, Experimental/pathology ; Inflammation/drug therapy ; Inflammation/genetics ; Inflammation/immunology ; Inflammation/pathology ; Interleukin-1alpha/genetics ; Interleukin-1alpha/immunology ; Lymphokines/genetics ; Lymphokines/immunology ; Mice ; Mice, Transgenic ; Multiple Sclerosis/drug therapy ; Multiple Sclerosis/genetics ; Multiple Sclerosis/pathology ; Platelet-Derived Growth Factor/genetics ; Platelet-Derived Growth Factor/immunology ; Signal Transduction/genetics ; Signal Transduction/immunology ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/immunology
Czasopismo naukowe
Tytuł :
Identification of a four immune-related genes signature based on an immunogenomic landscape analysis of clear cell renal cell carcinoma.
Autorzy :
Gao X; Clinical Laboratory, The First People's Hospital of Huaihua, Huaihua, Hunan, China.
Yang J; Clinical Laboratory, The First People's Hospital of Huaihua, Huaihua, Hunan, China.
Chen Y; Clinical Laboratory, The First Affiliated Hospital of University of South China, Hengyang, Hunan, China.
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Źródło :
Journal of cellular physiology [J Cell Physiol] 2020 Dec; Vol. 235 (12), pp. 9834-9850. Date of Electronic Publication: 2020 May 26.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Renal Cell/*immunology
Chemokine CXCL2/*genetics
Lymphokines/*genetics
Platelet-Derived Growth Factor/*genetics
Semaphorins/*genetics
Urocortins/*genetics
Adult ; Aged ; Biomarkers, Tumor/immunology ; Carcinoma, Renal Cell/genetics ; Carcinoma, Renal Cell/pathology ; Chemokine CXCL2/immunology ; Disease-Free Survival ; Female ; Gene Expression Regulation, Neoplastic/immunology ; Genome, Human/immunology ; Humans ; Immune Checkpoint Proteins/genetics ; Immune Checkpoint Proteins/immunology ; Immunogenetics ; Lymphokines/immunology ; Male ; Middle Aged ; Platelet-Derived Growth Factor/immunology ; Prognosis ; Proportional Hazards Models ; Semaphorins/immunology ; Transcriptome ; Urocortins/immunology
Czasopismo naukowe
Tytuł :
Proximal tubule LPA1 and LPA2 receptors use divergent signaling pathways to additively increase profibrotic cytokine secretion.
Autorzy :
Geng H; Department of Pathology, University of Texas Health Science Center, San Antonio, Texas.
Lan R; Department of Pathology, University of Texas Health Science Center, San Antonio, Texas.
Liu Y; Department of Pathology, University of Texas Health Science Center, San Antonio, Texas.
Chen W; Department of Pathology, University of Texas Health Science Center, San Antonio, Texas.
Wu M; Department of Pathology, University of Texas Health Science Center, San Antonio, Texas.
Saikumar P; Department of Pathology, University of Texas Health Science Center, San Antonio, Texas.
Weinberg JM; Department of Medicine, University of Michigan Medical Center, Ann Arbor, Michigan.
Venkatachalam MA; Department of Pathology, University of Texas Health Science Center, San Antonio, Texas.
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Źródło :
American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2021 Mar 01; Vol. 320 (3), pp. F359-F374. Date of Electronic Publication: 2021 Jan 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Acute Kidney Injury/*metabolism
Cytokines/*metabolism
Kidney Tubules, Proximal/*metabolism
Receptors, Lysophosphatidic Acid/*metabolism
Reperfusion Injury/*metabolism
Acute Kidney Injury/genetics ; Acute Kidney Injury/pathology ; Animals ; Cell Line ; Connective Tissue Growth Factor/metabolism ; Disease Models, Animal ; ErbB Receptors/metabolism ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Fibrosis ; Humans ; JNK Mitogen-Activated Protein Kinases/metabolism ; Kidney Tubules, Proximal/pathology ; Lymphokines/metabolism ; Male ; Mice ; Phosphorylation ; Platelet-Derived Growth Factor/metabolism ; Rats, Sprague-Dawley ; Receptors, Lysophosphatidic Acid/genetics ; Reperfusion Injury/genetics ; Reperfusion Injury/pathology ; Signal Transduction ; Transcription Factor AP-1/metabolism ; Transforming Growth Factor beta1/metabolism
Czasopismo naukowe
Tytuł :
Ancestry of the AUTS2 family-A novel group of polycomb-complex proteins involved in human neurological disease.
Autorzy :
Sellers RA; Evolution & Genomic Sciences, School of Biological Sciences, University of Manchester, Manchester, United Kingdom.
Robertson DL; MRC-University of Glasgow Centre for Virus Research, Garscube Campus, Glasgow, United Kingdom.
Tassabehji M; Evolution & Genomic Sciences, School of Biological Sciences, University of Manchester, Manchester, United Kingdom.
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Źródło :
PloS one [PLoS One] 2020 Dec 11; Vol. 15 (12), pp. e0232101. Date of Electronic Publication: 2020 Dec 11 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Evolution, Molecular*
Cytoskeletal Proteins/*genetics
Transcription Factors/*genetics
Animals ; Cytoskeletal Proteins/metabolism ; Drosophila melanogaster/genetics ; Genome/genetics ; Humans ; Lymphokines/genetics ; Lymphokines/metabolism ; Nuclear Proteins/genetics ; Phylogeny ; Polycomb-Group Proteins/genetics ; Sequence Homology, Nucleic Acid ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Selective BET-bromodomain inhibition by JQ1 suppresses dendritic cell maturation and antigen-specific T-cell responses.
Autorzy :
Remke N; Department of Oncology, Hematology, Immuno-Oncology and Rheumatology, University Hospital of Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Bisht S; Department of Oncology, Hematology, Immuno-Oncology and Rheumatology, University Hospital of Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Oberbeck S; Department of Oncology, Hematology, Immuno-Oncology and Rheumatology, University Hospital of Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Nolting J; Department of Oncology, Hematology, Immuno-Oncology and Rheumatology, University Hospital of Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Brossart P; Department of Oncology, Hematology, Immuno-Oncology and Rheumatology, University Hospital of Bonn, Venusberg-Campus 1, 53127, Bonn, Germany. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2021 Jan; Vol. 70 (1), pp. 107-121. Date of Electronic Publication: 2020 Jul 10.
Typ publikacji :
Journal Article
MeSH Terms :
Azepines/*pharmacology
Dendritic Cells/*drug effects
Immunity/*drug effects
Lymphokines/*immunology
Nerve Tissue Proteins/*antagonists & inhibitors
Receptors, Cell Surface/*antagonists & inhibitors
T-Lymphocytes/*drug effects
Triazoles/*pharmacology
Animals ; Antigens/immunology ; Cell Differentiation/drug effects ; Cell Differentiation/immunology ; Cell Proliferation/drug effects ; Cells, Cultured ; Coculture Techniques ; Cytokines/immunology ; Dendritic Cells/immunology ; Epigenesis, Genetic/drug effects ; Epigenesis, Genetic/immunology ; Female ; Immune Checkpoint Inhibitors/pharmacology ; Immunity/immunology ; Immunotherapy/methods ; Leukocyte Count/methods ; Lymphocyte Activation/drug effects ; Lymphocyte Activation/immunology ; Male ; Mice ; Mice, Inbred C57BL ; Signal Transduction/drug effects ; Signal Transduction/immunology ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł :
MicroRNA-29a inhibits glioblastoma stem cells and tumor growth by regulating the PDGF pathway.
Autorzy :
Yang Y; Department of Microbiology, Immunology and Cancer Biology, University of Virginia, PO Box 800168, Charlottesville, VA, 22908, USA.
Dodbele S; Department of Microbiology, Immunology and Cancer Biology, University of Virginia, PO Box 800168, Charlottesville, VA, 22908, USA.
Park T; Department of Microbiology, Immunology and Cancer Biology, University of Virginia, PO Box 800168, Charlottesville, VA, 22908, USA.
Glass R; Neurosurgical Research, University Clinics Munich, Munich, Germany.
Bhat K; Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Sulman EP; Department of Radiation Oncology, NYU Langone School of Medicine, New York, USA.
Zhang Y; Department of Microbiology, Immunology and Cancer Biology, University of Virginia, PO Box 800168, Charlottesville, VA, 22908, USA. .
Abounader R; Department of Microbiology, Immunology and Cancer Biology, University of Virginia, PO Box 800168, Charlottesville, VA, 22908, USA. .; Department of Neurology, University of Virginia, Charlottesville, VA, USA. .; Cancer Center, University of Virginia, Charlottesville, VA, USA. .
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Źródło :
Journal of neuro-oncology [J Neurooncol] 2019 Oct; Vol. 145 (1), pp. 23-34. Date of Electronic Publication: 2019 Sep 03.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Brain Neoplasms/*pathology
Glioblastoma/*pathology
Lymphokines/*metabolism
MicroRNAs/*genetics
Neoplastic Stem Cells/*pathology
Platelet-Derived Growth Factor/*metabolism
Animals ; Apoptosis ; Brain Neoplasms/genetics ; Brain Neoplasms/metabolism ; Cell Movement ; Cell Proliferation ; Glioblastoma/genetics ; Glioblastoma/metabolism ; Humans ; Lymphokines/genetics ; Mice ; Mice, SCID ; Neoplastic Stem Cells/metabolism ; Platelet-Derived Growth Factor/genetics ; Signal Transduction ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Defining Endothelial Cell-Derived Factors That Promote Pericyte Recruitment and Capillary Network Assembly.
Autorzy :
Kemp SS; Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa.
Aguera KN; Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa.
Cha B; Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa.
Davis GE; Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 Nov; Vol. 40 (11), pp. 2632-2648. Date of Electronic Publication: 2020 Aug 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Video-Audio Media
MeSH Terms :
Cell Movement*/drug effects
Neovascularization, Physiologic*/drug effects
Paracrine Communication*/drug effects
Angiogenic Proteins/*metabolism
Brain/*blood supply
Capillaries/*metabolism
Human Umbilical Vein Endothelial Cells/*metabolism
Pericytes/*metabolism
Angiogenic Proteins/pharmacology ; Becaplermin/metabolism ; Capillaries/cytology ; Capillaries/drug effects ; Cell Proliferation ; Cells, Cultured ; Coculture Techniques ; Endothelin-1/metabolism ; Heparin-binding EGF-like Growth Factor/metabolism ; Human Umbilical Vein Endothelial Cells/drug effects ; Humans ; Lymphokines/metabolism ; Pericytes/drug effects ; Platelet-Derived Growth Factor/metabolism ; Signal Transduction ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Tytuł :
The chemokine lymphotactin and its recombinant variants in oral cancer cell regulation.
Autorzy :
Abdullah Zubir AZ; Unit of Oral and Maxillofacial Pathology, School of Clinical Dentistry, University of Sheffield, Sheffield, UK.
Whawell SA; Unit of Oral and Maxillofacial Pathology, School of Clinical Dentistry, University of Sheffield, Sheffield, UK.
Wong TS; CheLSI, Chemical and Biological Engineering Department, University of Sheffield, Sheffield, UK.
Khurram SA; Unit of Oral and Maxillofacial Pathology, School of Clinical Dentistry, University of Sheffield, Sheffield, UK.
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Źródło :
Oral diseases [Oral Dis] 2020 Nov; Vol. 26 (8), pp. 1668-1676. Date of Electronic Publication: 2020 Jun 30.
Typ publikacji :
Journal Article
MeSH Terms :
Chemokines, C*/genetics
Mouth Neoplasms*/genetics
Cell Movement ; Chemokines ; Humans ; Lymphokines ; Sialoglycoproteins ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
De novo mutations in FBRSL1 cause a novel recognizable malformation and intellectual disability syndrome.
Autorzy :
Ufartes R; Institute of Human Genetics, University Medical Center Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany.
Berger H; Department of Biology, Molecular Embryology, Philipps-University Marburg, Marburg, Germany.
Till K; Department of Biology, Molecular Embryology, Philipps-University Marburg, Marburg, Germany.
Salinas G; NGS Integrative Genomics Core Unit, University Medical Center Göttingen, 37073, Göttingen, Germany.
Sturm M; Institute of Medical Genetics and Applied Genomics, Calwerstr. 7, 72076, Tübingen, Germany.
Altmüller J; Cologne Center for Genomics (CCG), University of Cologne, Weyertal 115b, 50931, Cologne, Germany.
Nürnberg P; Cologne Center for Genomics (CCG), University of Cologne, Weyertal 115b, 50931, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Robert-Koch Str. 21, 50931, Cologne, Germany.
Thiele H; Cologne Center for Genomics (CCG), University of Cologne, Weyertal 115b, 50931, Cologne, Germany.
Funke R; Department of Neuropediatrics, Sozialpädiatrisches Zentrum, Mönchebergstr. 41-43, 34125, Kassel, Germany.
Apeshiotis N; Praxis für Humangenetik, Georg-Eckert-Straße 12, 38100, Brunswick, Germany.
Langen H; Department of Neuropediatrics, Sozialpädiatrisches Zentrum Hannover, Janusz-Korczak-Allee 8, 30173, Hannover, Germany.
Wollnik B; Institute of Human Genetics, University Medical Center Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: From Molecular Machines To Networks of Excitable Cells' (MBExC), University of Göttingen, 37073, Göttingen, Germany.
Borchers A; Department of Biology, Molecular Embryology, Philipps-University Marburg, Marburg, Germany. .; DFG Research Training Group, Membrane Plasticity in Tissue Development and Remodeling, GRK 2213, Philipps-University Marburg, Marburg, Germany. .
Pauli S; Institute of Human Genetics, University Medical Center Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany. .
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Źródło :
Human genetics [Hum Genet] 2020 Nov; Vol. 139 (11), pp. 1363-1379. Date of Electronic Publication: 2020 May 18.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Intellectual Disability/*genetics
Lymphokines/*genetics
Mutation/*genetics
Abnormalities, Multiple/genetics ; Adolescent ; Animals ; Child ; Exons/genetics ; Humans ; Male ; Phenotype ; Protein Isoforms/genetics ; Syndrome ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
T regulatory cells-derived extracellular vesicles and their contribution to the generation of immune tolerance.
Autorzy :
Rojas C; Centro de Investigación Biomédica, Facultad de Medicina, Universidad de los Andes, Las Condes, Santiago, Chile.; Periodontal Biology Laboratory, Faculty of Dentistry, Universidad de Chile, Las Condes, Santiago, Chile.
Campos-Mora M; Centro de Investigación Biomédica, Facultad de Medicina, Universidad de los Andes, Las Condes, Santiago, Chile.
Cárcamo I; Centro de Investigación Biomédica, Facultad de Medicina, Universidad de los Andes, Las Condes, Santiago, Chile.
Villalón N; Centro de Investigación Biomédica, Facultad de Medicina, Universidad de los Andes, Las Condes, Santiago, Chile.
Elhusseiny A; Centro de Investigación Biomédica, Facultad de Medicina, Universidad de los Andes, Las Condes, Santiago, Chile.
Contreras-Kallens P; Centro de Investigación Biomédica, Facultad de Medicina, Universidad de los Andes, Las Condes, Santiago, Chile.
Refisch A; Centro de Investigación Biomédica, Facultad de Medicina, Universidad de los Andes, Las Condes, Santiago, Chile.
Gálvez-Jirón F; Centro de Investigación Biomédica, Facultad de Medicina, Universidad de los Andes, Las Condes, Santiago, Chile.
Emparán I; Centro de Investigación Biomédica, Facultad de Medicina, Universidad de los Andes, Las Condes, Santiago, Chile.
Montoya-Riveros A; Centro de Investigación Biomédica, Facultad de Medicina, Universidad de los Andes, Las Condes, Santiago, Chile.
Vernal R; Periodontal Biology Laboratory, Faculty of Dentistry, Universidad de Chile, Las Condes, Santiago, Chile.
Pino-Lagos K; Centro de Investigación Biomédica, Facultad de Medicina, Universidad de los Andes, Las Condes, Santiago, Chile.
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Źródło :
Journal of leukocyte biology [J Leukoc Biol] 2020 Sep; Vol. 108 (3), pp. 813-824. Date of Electronic Publication: 2020 Jun 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Extracellular Vesicles/*immunology
Immune Tolerance/*immunology
T-Lymphocytes, Regulatory/*immunology
Animals ; B-Lymphocyte Subsets/immunology ; Cellular Microenvironment ; Forkhead Transcription Factors/physiology ; Gene Silencing ; Humans ; Immune Checkpoint Proteins/physiology ; Immune Tolerance/genetics ; Immunotherapy ; Inflammation/immunology ; Lymphokines/metabolism ; Mice ; MicroRNAs/genetics ; Models, Immunological ; Receptors, Immunologic/physiology
Czasopismo naukowe
Tytuł :
Identification of platelet-derived growth factor C as a mediator of both renal fibrosis and hypertension.
Autorzy :
van Roeyen CRC; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University, Aachen, Germany. Electronic address: .
Martin IV; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University, Aachen, Germany.
Drescher A; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University, Aachen, Germany.
Schuett KA; Division of Cardiology, RWTH Aachen University, Aachen, Germany.
Hermert D; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University, Aachen, Germany.
Raffetseder U; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University, Aachen, Germany.
Otten S; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University, Aachen, Germany.
Buhl EM; Institute of Pathology, RWTH Aachen University, Aachen, Germany.
Braun GS; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University, Aachen, Germany.
Kuppe C; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University, Aachen, Germany.
Liehn E; Institute for Molecular Cardiovascular Research, RWTH Aachen University, Aachen, Germany.
Boor P; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University, Aachen, Germany; Institute of Pathology, RWTH Aachen University, Aachen, Germany.
Weiskirchen R; Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry RWTH Aachen University, Aachen, Germany.
Eriksson U; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Gross O; Division of Nephrology and Rheumatology, University Medicine Göttingen, Göttingen, Germany.
Eitner F; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University, Aachen, Germany; Kidney Diseases Research, Bayer AG, Wuppertal, Germany.
Floege J; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University, Aachen, Germany.
Ostendorf T; Division of Nephrology and Clinical Immunology, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University, Aachen, Germany.
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Źródło :
Kidney international [Kidney Int] 2019 May; Vol. 95 (5), pp. 1103-1119. Date of Electronic Publication: 2019 Feb 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hypertension/*pathology
Kidney/*pathology
Lymphokines/*metabolism
Platelet-Derived Growth Factor/*metabolism
Angiotensinogen/metabolism ; Animals ; Blood Pressure/genetics ; Cells, Cultured ; Collagen Type IV/genetics ; Disease Models, Animal ; Fibrosis ; Hepatocytes ; Humans ; Hypertension/etiology ; Hypertension/genetics ; Lymphokines/antagonists & inhibitors ; Male ; Mice ; Mice, Knockout ; Platelet-Derived Growth Factor/antagonists & inhibitors ; Primary Cell Culture ; Up-Regulation ; Ureter/surgery
Czasopismo naukowe
Tytuł :
PDGF-B Is Required for Development of the Glymphatic System.
Autorzy :
Munk AS; Center for Translational Neuromedicine, University of Rochester, Rochester, NY 14642, USA; Center for Basic and Translational Neuroscience, University of Copenhagen, 2200 Copenhagen, Denmark.
Wang W; Center for Translational Neuromedicine, University of Rochester, Rochester, NY 14642, USA.
Bèchet NB; Department of Experimental Medical Science, Lund University, 221 84 Lund, Sweden; Wallenberg Center for Molecular Medicine, Lund University, 221 84 Lund, Sweden.
Eltanahy AM; Department of Experimental Medical Science, Lund University, 221 84 Lund, Sweden; Wallenberg Center for Molecular Medicine, Lund University, 221 84 Lund, Sweden; Mansoura University Hospital, Faculty of Medicine, Mansoura University, 35516 Mansoura, Egypt.
Cheng AX; Center for Translational Neuromedicine, University of Rochester, Rochester, NY 14642, USA.
Sigurdsson B; Center for Basic and Translational Neuroscience, University of Copenhagen, 2200 Copenhagen, Denmark.
Benraiss A; Center for Translational Neuromedicine, University of Rochester, Rochester, NY 14642, USA.
Mäe MA; Department of Immunology, Genetics and Pathology, Uppsala University, 751 85 Uppsala, Sweden.
Kress BT; Center for Translational Neuromedicine, University of Rochester, Rochester, NY 14642, USA; Center for Basic and Translational Neuroscience, University of Copenhagen, 2200 Copenhagen, Denmark.
Kelley DH; Department of Mechanical Engineering, University of Rochester, Rochester, NY 14627, USA.
Betsholtz C; Department of Immunology, Genetics and Pathology, Uppsala University, 751 85 Uppsala, Sweden; Integrated Cardio Metabolic Center (ICMC), Karolinska Institutet, Novum, 141 57 Huddinge, Sweden.
Møllgård K; Department of Cellular and Molecular Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.
Meissner A; Department of Experimental Medical Science, Lund University, 221 84 Lund, Sweden; Wallenberg Center for Molecular Medicine, Lund University, 221 84 Lund, Sweden.
Nedergaard M; Center for Translational Neuromedicine, University of Rochester, Rochester, NY 14642, USA; Center for Basic and Translational Neuroscience, University of Copenhagen, 2200 Copenhagen, Denmark.
Lundgaard I; Center for Translational Neuromedicine, University of Rochester, Rochester, NY 14642, USA; Department of Experimental Medical Science, Lund University, 221 84 Lund, Sweden; Wallenberg Center for Molecular Medicine, Lund University, 221 84 Lund, Sweden. Electronic address: .
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Źródło :
Cell reports [Cell Rep] 2019 Mar 12; Vol. 26 (11), pp. 2955-2969.e3.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Astrocytes/*metabolism
Glymphatic System/*growth & development
Lymphokines/*genetics
Platelet-Derived Growth Factor/*genetics
Animals ; Aquaporin 4/genetics ; Aquaporin 4/metabolism ; Astrocytes/cytology ; Female ; Glymphatic System/metabolism ; Hippocampus/growth & development ; Hippocampus/metabolism ; Lymphokines/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Platelet-Derived Growth Factor/metabolism ; Protein Transport
Czasopismo naukowe
Tytuł :
Using T cell lymphokines to enhance the immune response against Newcastle disease in vaccinated broiler chickens fed naturally contaminated diet with different mycotoxins.
Autorzy :
Saud, B. H.
AL-Zuhariy, M. T.
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Alternatywny tytuł :
استعمال اللمفوكاينز للخلايا التائية لتعزيز الاستجابة المناعية ضد مرض النيوكاسل في دجاج اللاحم الملقح المستهلكة لعلائق ملوثة طبيعيا بسموم فطرية
Źródło :
Iraqi Journal of Veterinary Sciences. 2020, Vol. 34 Issue 2, p427-433. 7p.
Czasopismo naukowe
Tytuł :
Perivascular Adipose Tissue-Derived PDGF-D Contributes to Aortic Aneurysm Formation During Obesity.
Autorzy :
Zhang ZB; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Ruan CC; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China .
Lin JR; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Xu L; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Chen XH; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Du YN; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Fu MX; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Kong LR; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Zhu DL; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Gao PJ; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China .
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Źródło :
Diabetes [Diabetes] 2018 Aug; Vol. 67 (8), pp. 1549-1560. Date of Electronic Publication: 2018 May 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aorta, Abdominal/*metabolism
Aortic Aneurysm, Abdominal/*etiology
Intra-Abdominal Fat/*metabolism
Lymphokines/*metabolism
Obesity/*physiopathology
Platelet-Derived Growth Factor/*metabolism
Adventitia/drug effects ; Adventitia/immunology ; Adventitia/metabolism ; Adventitia/pathology ; Angiotensin II/administration & dosage ; Angiotensin II/adverse effects ; Animals ; Aorta, Abdominal/diagnostic imaging ; Aorta, Abdominal/drug effects ; Aorta, Abdominal/pathology ; Aortic Aneurysm, Abdominal/diagnostic imaging ; Aortic Aneurysm, Abdominal/metabolism ; Aortic Aneurysm, Abdominal/pathology ; Benzimidazoles/pharmacology ; Cells, Cultured ; Diet, High-Fat/adverse effects ; Drug Implants ; Gene Expression Regulation/drug effects ; Inflammation Mediators/metabolism ; Intra-Abdominal Fat/drug effects ; Intra-Abdominal Fat/immunology ; Intra-Abdominal Fat/pathology ; Lymphokines/agonists ; Lymphokines/antagonists & inhibitors ; Lymphokines/genetics ; Male ; Mice ; Mice, Mutant Strains ; Mice, Transgenic ; Obesity/etiology ; Obesity/metabolism ; Obesity/pathology ; Organ Specificity ; Platelet-Derived Growth Factor/agonists ; Platelet-Derived Growth Factor/antagonists & inhibitors ; Platelet-Derived Growth Factor/genetics ; Quinolines/pharmacology ; Recombinant Proteins/chemistry ; Recombinant Proteins/metabolism ; Subcutaneous Fat, Abdominal/drug effects ; Subcutaneous Fat, Abdominal/immunology ; Subcutaneous Fat, Abdominal/metabolism ; Subcutaneous Fat, Abdominal/pathology ; Survival Analysis
Czasopismo naukowe
Tytuł :
Ecto-Nucleotide Triphosphate Diphosphohydrolase-2 (NTPDase2) Deletion Increases Acetaminophen-Induced Hepatotoxicity.
Autorzy :
Feldbrügge L; Department of Surgery, Campus Charité Mitte and Campus Virchow Klinikum, Charité-Universitätsmedizin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.; Translational Centre for Regenerative Medicine (TRM), Universität Leipzig, 04103 Leipzig, Germany.
Splith K; Department of Surgery, Campus Charité Mitte and Campus Virchow Klinikum, Charité-Universitätsmedizin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.; Translational Centre for Regenerative Medicine (TRM), Universität Leipzig, 04103 Leipzig, Germany.
Kämmerer I; Translational Centre for Regenerative Medicine (TRM), Universität Leipzig, 04103 Leipzig, Germany.
Richter S; Department of Surgery, Campus Charité Mitte and Campus Virchow Klinikum, Charité-Universitätsmedizin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.
Riddermann A; Department of Surgery, Campus Charité Mitte and Campus Virchow Klinikum, Charité-Universitätsmedizin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.
Ortiz Galindo SA; Department of Surgery, Campus Charité Mitte and Campus Virchow Klinikum, Charité-Universitätsmedizin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.
Krenzien F; Department of Surgery, Campus Charité Mitte and Campus Virchow Klinikum, Charité-Universitätsmedizin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.; Translational Centre for Regenerative Medicine (TRM), Universität Leipzig, 04103 Leipzig, Germany.
Müller T; Division of Hepatology and Gastroenterology, Medical Department, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.
Csizmadia E; Departments of Medicine and Anesthesia, Beth Israel Deaconess Medical Center, Harvard Medical School, Harvard University, Boston, MA 02215, USA.
Pratschke J; Department of Surgery, Campus Charité Mitte and Campus Virchow Klinikum, Charité-Universitätsmedizin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.
Robson SC; Departments of Medicine and Anesthesia, Beth Israel Deaconess Medical Center, Harvard Medical School, Harvard University, Boston, MA 02215, USA.
Schmelzle M; Department of Surgery, Campus Charité Mitte and Campus Virchow Klinikum, Charité-Universitätsmedizin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.; Translational Centre for Regenerative Medicine (TRM), Universität Leipzig, 04103 Leipzig, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Aug 20; Vol. 21 (17). Date of Electronic Publication: 2020 Aug 20.
Typ publikacji :
Journal Article
MeSH Terms :
Acetaminophen/*adverse effects
Adenosine Triphosphatases/*genetics
Chemical and Drug Induced Liver Injury/*etiology
Adenosine Triphosphatases/metabolism ; Alanine Transaminase/blood ; Alkaline Phosphatase/blood ; Animals ; Chemical and Drug Induced Liver Injury/pathology ; Fibroblasts/drug effects ; Fibroblasts/pathology ; Gene Expression Regulation, Enzymologic/drug effects ; Interleukin-6/genetics ; Liver/drug effects ; Liver/pathology ; Liver Regeneration/drug effects ; Liver Regeneration/physiology ; Lymphokines/genetics ; Male ; Mice, Inbred C57BL ; Mice, Mutant Strains ; Necrosis ; Platelet-Derived Growth Factor/genetics ; Tumor Necrosis Factor-alpha/genetics
Czasopismo naukowe
Tytuł :
[Association between platelet-derived growth factor-C single nucleotide polymorphisms and nonsyndromic cleft lip with or without cleft palate in Western Chinese population].
Autorzy :
Zhou YL; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Cleft Lip and Palate Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Zhu WC; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Cleft Lip and Palate Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Shi B; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Cleft Lip and Palate Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Jia ZL; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Cleft Lip and Palate Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
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Źródło :
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology [Hua Xi Kou Qiang Yi Xue Za Zhi] 2020 Aug 01; Vol. 38 (4), pp. 364-370.
Typ publikacji :
Journal Article
MeSH Terms :
Cleft Lip*
Cleft Palate*
Case-Control Studies ; Genetic Predisposition to Disease ; Genotype ; Humans ; Lymphokines ; Platelet-Derived Growth Factor ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł :
Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth.
Autorzy :
Lechertier T; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK.
Reynolds LE; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK.
Kim H; Cell Death & Inflammation, The Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK.
Pedrosa AR; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK.
Gómez-Escudero J; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK.
Muñoz-Félix JM; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK.
Batista S; Systems Oncology Group, Champalimaud Research, Champalimaud Centre for the Unknown Av. Brasília, Doca de Pedrouços, 1400-038, Lisbon, Portugal.
Dukinfield M; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK.
Demircioglu F; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK.
Wong PP; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK.; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 510120, Guangzhou, China.
Matchett KP; Centre for Inflammation Research, The Queen's Medical Research Institute, Edinburgh BioQuarter, University of Edinburgh, Edinburgh, UK.
Henderson NC; Centre for Inflammation Research, The Queen's Medical Research Institute, Edinburgh BioQuarter, University of Edinburgh, Edinburgh, UK.; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road South, Edinburgh, UK.
D'Amico G; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK.
Parsons M; Nikon Imaging 's, Randall Division of Cell and Molecular Biophysics, Kings College London, Room 3.22B, New Hunts House Guys Campus, London, SE1 1UL, UK.
Harwood C; Centre for Cell Biology and Cutaneous Research, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, E1 2AT, UK.
Meier P; Cell Death & Inflammation, The Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK.
Hodivala-Dilke KM; Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK. .
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Źródło :
Nature communications [Nat Commun] 2020 Jun 04; Vol. 11 (1), pp. 2810. Date of Electronic Publication: 2020 Jun 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Neovascularization, Pathologic*
Cysteine-Rich Protein 61/*metabolism
Focal Adhesion Kinase 1/*metabolism
Intercellular Signaling Peptides and Proteins/*metabolism
Pericytes/*metabolism
Proto-Oncogene Proteins/*metabolism
Receptor Protein-Tyrosine Kinases/*metabolism
Animals ; Aorta, Thoracic/pathology ; Carcinoma, Lewis Lung/metabolism ; Cell Adhesion ; Cell Proliferation ; Female ; Focal Adhesion Kinase 1/genetics ; Humans ; Lymphokines/metabolism ; Male ; Melanoma/blood supply ; Melanoma/metabolism ; Melanoma, Experimental ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Neoplasms/pathology ; Placenta Growth Factor/metabolism ; Platelet-Derived Growth Factor/metabolism ; Proto-Oncogene Proteins c-sis/metabolism ; Signal Transduction ; Tumor Microenvironment ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Tytuł :
Platelet-derived growth factor-C and -D in the cardiovascular system and diseases.
Autorzy :
Lee C; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, PR China.
Li X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, PR China. Electronic address: .
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Źródło :
Molecular aspects of medicine [Mol Aspects Med] 2018 Aug; Vol. 62, pp. 12-21. Date of Electronic Publication: 2017 Oct 13.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cardiovascular Diseases/*metabolism
Cardiovascular System/*metabolism
Lymphokines/*metabolism
Platelet-Derived Growth Factor/*metabolism
Animals ; Cardiovascular Diseases/genetics ; Gene Expression Regulation ; Humans ; Lymphokines/genetics ; Neovascularization, Physiologic ; Platelet-Derived Growth Factor/genetics ; Receptors, Platelet-Derived Growth Factor/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
PDGF-C and PDGF-D signaling in vascular diseases and animal models.
Autorzy :
Folestad E; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Kunath A; Division of Drug Research, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.
Wågsäter D; Division of Drug Research, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden. Electronic address: .
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Źródło :
Molecular aspects of medicine [Mol Aspects Med] 2018 Aug; Vol. 62, pp. 1-11. Date of Electronic Publication: 2018 Feb 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Lymphokines/*metabolism
Platelet-Derived Growth Factor/*metabolism
Vascular Diseases/*metabolism
Animals ; Cardiovascular System/metabolism ; Disease Models, Animal ; Gene Expression Regulation ; Humans ; Lymphokines/genetics ; Neovascularization, Physiologic ; Platelet-Derived Growth Factor/genetics ; Polymorphism, Single Nucleotide ; Receptor, Platelet-Derived Growth Factor alpha/genetics ; Receptor, Platelet-Derived Growth Factor alpha/metabolism ; Receptor, Platelet-Derived Growth Factor beta/genetics ; Receptor, Platelet-Derived Growth Factor beta/metabolism ; Signal Transduction ; Vascular Diseases/genetics
Czasopismo naukowe
Tytuł :
Preclinical toxicological assessment of a novel monoclonal antibody targeting human platelet-derived growth factor CC (PDGF-CC) in PDGF-CChum mice.
Autorzy :
Zeitelhofer M; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Li H; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Adzemovic MZ; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Nilsson I; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Muhl L; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Scott AM; Olivia Newton-John Cancer Research Institute, and School of Cancer Medicine, La Trobe University, Melbourne, Australia.
Eriksson U; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
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Źródło :
PloS one [PLoS One] 2018 Jul 18; Vol. 13 (7), pp. e0200649. Date of Electronic Publication: 2018 Jul 18 (Print Publication: 2018).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Monoclonal, Murine-Derived/*pharmacology
Antibodies, Neutralizing/*pharmacology
Lymphokines/*antagonists & inhibitors
Platelet-Derived Growth Factor/*antagonists & inhibitors
Animals ; Antibodies, Monoclonal, Murine-Derived/adverse effects ; Antibodies, Monoclonal, Murine-Derived/immunology ; Antibodies, Neutralizing/administration & dosage ; Antibodies, Neutralizing/immunology ; Drug Evaluation, Preclinical ; Humans ; Lymphokines/immunology ; Mice ; Mice, Transgenic ; Platelet-Derived Growth Factor/immunology
Czasopismo naukowe

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