- Tytuł:
- Multi-omics and pathway analyses of genome-wide associations implicate regulation and immunity in verbal declarative memory performance.
- Autorzy:
-
Mei H; Department of Data Science, John D. Bower School of Population Health, University of Mississippi Medical Center, Jackson, MS, USA. .; Gertrude C. Ford Memory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson, MS, USA. .
Simino J; Department of Data Science, John D. Bower School of Population Health, University of Mississippi Medical Center, Jackson, MS, USA. .; Gertrude C. Ford Memory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson, MS, USA. .
Li L; Department of Biology, Tougaloo College, Jackson, MS, USA.
Jiang F; Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Bis JC; Department of Medicine, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.
Davies G; Department of Psychology, Lothian Birth Cohorts Group, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK.
Hill WD; Department of Psychology, Lothian Birth Cohorts Group, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK.
Xia C; Department of Psychology, Lothian Birth Cohorts Group, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK.
Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Yang Q; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; The National Heart Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.Lahti J; Turku Institute for Advanced Research, University of Turku, Turku, Finland.; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Kirin M; Work completed while at The University of Edinburgh, Edinburgh, UK.
De Jager P; Taub Institute for Research On Alzheimer's Disease and the Aging Brain, Columbia Irving University Medical Center, New York, NY, USA.; Center for Translational and Computational Neuro-Immunology, Columbia University Medical Center, New York, NY, USA.; Department of Neurology, Columbia University Medical Center, New York, NY, USA.
Armstrong NJ; Mathematics and Statistics, Curtin University, Perth, Australia.
Ghanbari M; Department of Epidemiology, Erasmus Medical Center University Medical Center, Rotterdam, The Netherlands.
Kolcic I; School of Medicine, University of Split, Split, Croatia.
Moran C; Department of Geriatric Medicine, Frankston Hospital, Peninsula Health, Melbourne, Australia.; Peninsula Clinical School, Central Clinical School, Monash University, Melbourne, Australia.
Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
Sargurupremraj M; Inserm, Bordeaux Population Health Research Center, Team VINTAGE, UMR 1219, University of Bordeaux, Bordeaux, France.
Mahmud S; Department of Data Science, John D. Bower School of Population Health, University of Mississippi Medical Center, Jackson, MS, USA.
Fornage M; The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Satizabal CL; The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Polasek O; School of Medicine, University of Split, Split, Croatia.; Algebra University College, Ilica 242, Zagreb, Croatia.
Räikkönen K; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Liewald DC; Department of Psychology, Lothian Birth Cohorts Group, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK.
Homuth G; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
Callisaya M; Peninsula Clinical School, Central Clinical School, Monash University, Melbourne, Australia.; Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia.
Mather KA; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, Australia.; Neuroscience Research Australia, Sydney, Australia.
Windham BG; Gertrude C. Ford Memory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson, MS, USA.; Department of Medicine, Division of Geriatrics, School of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
Zemunik T; School of Medicine, University of Split, Split, Croatia.
Palotie A; Department of Medicine, Department of Neurology and Department of Psychiatry, Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; The Stanley Center for Psychiatric Research and Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Pattie A; Department of Psychology, Lothian Birth Cohorts Group, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK.
van der Auwera S; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
Thalamuthu A; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, Australia.; Neuroscience Research Australia, Sydney, Australia.
Knopman DS; Department of Neurology, Mayo Clinic, Rochester, MN, USA.
Rudan I; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK.
Starr JM; Department of Psychology, Lothian Birth Cohorts Group, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, EH8 9JZ, UK.
Wittfeld K; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.; German Center for Neurodegenerative Diseases (DZNE), Site Rostock/ Greifswald, Rostock, Germany.
Kochan NA; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, Australia.
Griswold ME; Gertrude C. Ford Memory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson, MS, USA.; Department of Medicine, School of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
Vitart V; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Brodaty H; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, Australia.; Dementia Centre for Research Collaboration, University of New South Wales, Sydney, NSW, Australia.
Gottesman R; Stroke, Cognition, and Neuroepidemiology (SCAN) Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Cox SR; Department of Psychology, Lothian Birth Cohorts Group, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK.
Psaty BM; Department of Medicine, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
Boerwinkle E; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Chasman DI; Harvard Medical School, Boston, MA, USA.; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Grodstein F; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Epidemiology, Harvard T.H Chan School of Public Health, Harvard University, Boston, MA, USA.
Sachdev PS; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, Australia.; Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, Australia.
Srikanth V; Department of Geriatric Medicine, Frankston Hospital, Peninsula Health, Melbourne, Australia.; Peninsula Clinical School, Central Clinical School, Monash University, Melbourne, Australia.; Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia.
Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Wilson JF; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK.; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Eriksson JG; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Department of Public Health Solutions, Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.; Folkhälsan Research Centre, Helsinki, Finland.
Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.; German Center for Neurodegenerative Diseases (DZNE), Site Rostock/ Greifswald, Rostock, Germany.
Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
Ikram MA; Department of Epidemiology, Erasmus Medical Center University Medical Center, Rotterdam, The Netherlands.
Deary IJ; Department of Psychology, Lothian Birth Cohorts Group, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK.
van Duijn CM; Nuffield Department of Population Health, Medical Sciences Division, University of Oxford, Oxford, UK.
Launer L; Laboratory of Epidemiology and Population Sciences, National Institute On Aging, Bethesda, MD, USA.
Fitzpatrick AL; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Family Medicine, University of Washington, Seattle, WA, USA.
Seshadri S; The National Heart Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
Bressler J; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
Debette S; Inserm, Bordeaux Population Health Research Center, Team VINTAGE, UMR 1219, University of Bordeaux, Bordeaux, France.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Neurology, CHU de Bordeaux, Bordeaux, France.
Mosley TH Jr; Gertrude C. Ford Memory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson, MS, USA.; Department of Medicine, School of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.; Department of Neurology, University of Mississippi Medical Center, Jackson, MS, USA. - Pokaż więcej
- Źródło:
- Alzheimer's research & therapy [Alzheimers Res Ther] 2024 Jan 20; Vol. 16 (1), pp. 14. Date of Electronic Publication: 2024 Jan 20.
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
- MeSH Terms:
-
Genome-Wide Association Study*/methods
MicroRNAs*
Humans ; Aged ; Multiomics ; Memory ; Cognition ; Polymorphism, Single Nucleotide/genetics
Czasopismo naukowe