Human PARP1 Facilitates Transcription through a Nucleosome and Histone Displacement by Pol II In Vitro.
Autorzy:
Kotova EY; Fox Chase Cancer Center, Philadelphia, PA 19111, USA. Hsieh FK; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA. Chang HW; Fox Chase Cancer Center, Philadelphia, PA 19111, USA.; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA.; Howard Hughes Medical Institute, New York University Grossman School of Medicine, New York, NY 10016, USA. Maluchenko NV; Biology Faculty, Lomonosov Moscow State University, 119234 Moscow, Russia. LangelierMF; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada. Pascal JM; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada. Luse DS; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA. Feofanov AV; Biology Faculty, Lomonosov Moscow State University, 119234 Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia. Studitsky VM; Fox Chase Cancer Center, Philadelphia, PA 19111, USA.; Biology Faculty, Lomonosov Moscow State University, 119234 Moscow, Russia.
Maluchenko NV; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia. Nilov DK; Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia. Pushkarev SV; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119991 Moscow, Russia. Kotova EY; Fox Chase Cancer Center, Philadelphia, PA 19111-2497, USA. Gerasimova NS; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia. Kirpichnikov MP; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia. LangelierMF; Department of Biochemistry and Molecular Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, QC H3T 1J4, Canada. Pascal JM; Department of Biochemistry and Molecular Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, QC H3T 1J4, Canada. Akhtar MS; Molecular and Structural Biology Division, CSIR-Central Drug Research Institute, Lucknow 226031, Uttar Pradesh, India. Feofanov AV; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia. Studitsky VM; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.; Fox Chase Cancer Center, Philadelphia, PA 19111-2497, USA.
Structural basis for allosteric PARP-1 retention on DNA breaks.
Autorzy:
Zandarashvili L; Department of Biochemistry and Biophysics, Penn Center for Genome Integrity, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. LangelierMF; Département de Biochimie and Médecine Moléculaire, Faculté de Médecine, Université de Montréal, Montréal, QC H3C 3J7, Canada. Velagapudi UK; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY 11439, USA. Hancock MA; SPR-MS Facility, McGill University, Montréal, Quebec, Canada. Steffen JD; Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA. Billur R; Department of Biochemistry and Biophysics, Penn Center for Genome Integrity, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Hannan ZM; Department of Biochemistry and Biophysics, Penn Center for Genome Integrity, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Wicks AJ; CRUK Gene Function Laboratory and Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London SW3 6JB, UK. Krastev DB; CRUK Gene Function Laboratory and Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London SW3 6JB, UK. Pettitt SJ; CRUK Gene Function Laboratory and Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London SW3 6JB, UK. Lord CJ; CRUK Gene Function Laboratory and Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London SW3 6JB, UK. Talele TT; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY 11439, USA. Pascal JM; Département de Biochimie and Médecine Moléculaire, Faculté de Médecine, Université de Montréal, Montréal, QC H3C 3J7, Canada. . Black BE; Department of Biochemistry and Biophysics, Penn Center for Genome Integrity, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. .
Unfolding of core nucleosomes by PARP-1 revealed by spFRET microscopy.
Autorzy:
Sultanov DC; Biology Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia.; Fox Chase Cancer Center, Philadelphia, PA, 19111-2497, USA. Gerasimova NS; Biology Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia. Kudryashova KS; Biology Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of Russian Academy of Sciences, 117997 Moscow, Russia. Maluchenko NV; Biology Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia. Kotova EY; Fox Chase Cancer Center, Philadelphia, PA, 19111-2497, USA. LangelierMF; Department of Biochemistry and Molecular Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montréal, QC H3T 1J4, Canada. Pascal JM; Department of Biochemistry and Molecular Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montréal, QC H3T 1J4, Canada. Kirpichnikov MP; Fox Chase Cancer Center, Philadelphia, PA, 19111-2497, USA. Feofanov AV; Biology Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of Russian Academy of Sciences, 117997 Moscow, Russia. Studitsky VM; Biology Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia.; Fox Chase Cancer Center, Philadelphia, PA, 19111-2497, USA.
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Źródło:
AIMS genetics [AIMS Genet] 2017; Vol. 4 (1), pp. 21-31. Date of Electronic Publication: 2017 Jan 05.
A PARP1-ERK2 synergism is required for the induction of LTP.
Autorzy:
Visochek L; Neufeld Cardiac Research institute, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel. Grigoryan G; Department of Neurobiology, the Weizmann Institute of Science, Rehovot 76100, Israel. Kalal A; Neufeld Cardiac Research institute, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel.; Department of Physiology and Pharmacology, Tel-Aviv University, Tel-Aviv 69978, Israel. Milshtein-Parush H; Department of Physiology and Pharmacology, Tel-Aviv University, Tel-Aviv 69978, Israel.; Sagol School of Neuroscience, Tel-Aviv University, Tel-Aviv 69978, Israel. Gazit N; Department of Physiology and Pharmacology, Tel-Aviv University, Tel-Aviv 69978, Israel.; Sagol School of Neuroscience, Tel-Aviv University, Tel-Aviv 69978, Israel. Slutsky I; Department of Physiology and Pharmacology, Tel-Aviv University, Tel-Aviv 69978, Israel.; Sagol School of Neuroscience, Tel-Aviv University, Tel-Aviv 69978, Israel. Yeheskel A; Bioinformatics Unit, George S. Wise Faculty of Life Sciences, Tel-Aviv University, Tel-Aviv 69978, Israel. Shainberg A; Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, 52900 Ramat Gan, Israel. Castiel A; Cancer Research Center, Sheba Medical Center, 53621 Ramat Gan, Israel. Seger R; Department of Biological Regulation, the Weizmann Institute of Science, Rehovot 76100, Israel. LangelierMF; Department of Biochemistry and Molecular Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, USA. Dantzer F; Biotechnology and Cell Signaling, UMR7242, Ecole Superieure de Biotechnologie Strasbourg, F-67400, Illkrich-Graffenstaden, France. Pascal JM; Department of Biochemistry and Molecular Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, USA. Segal M; Department of Neurobiology, the Weizmann Institute of Science, Rehovot 76100, Israel. Cohen-Armon M; Neufeld Cardiac Research institute, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel.; Department of Physiology and Pharmacology, Tel-Aviv University, Tel-Aviv 69978, Israel.; Sagol School of Neuroscience, Tel-Aviv University, Tel-Aviv 69978, Israel.
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Źródło:
Scientific reports [Sci Rep] 2016 Apr 28; Vol. 6, pp. 24950. Date of Electronic Publication: 2016 Apr 28.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Structural basis for DNA damage-dependent poly(ADP-ribosyl)ation by human PARP-1.
Autorzy:
LangelierMF; Department of Biochemistry and Molecular Biology, The Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA. Planck JL Roy S Pascal JM
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