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Wyświetlanie 1-9 z 9
Tytuł:
Human PARP1 Facilitates Transcription through a Nucleosome and Histone Displacement by Pol II In Vitro.
Autorzy:
Kotova EY; Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Hsieh FK; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
Chang HW; Fox Chase Cancer Center, Philadelphia, PA 19111, USA.; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA.; Howard Hughes Medical Institute, New York University Grossman School of Medicine, New York, NY 10016, USA.
Maluchenko NV; Biology Faculty, Lomonosov Moscow State University, 119234 Moscow, Russia.
Langelier MF; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada.
Pascal JM; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada.
Luse DS; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Feofanov AV; Biology Faculty, Lomonosov Moscow State University, 119234 Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Studitsky VM; Fox Chase Cancer Center, Philadelphia, PA 19111, USA.; Biology Faculty, Lomonosov Moscow State University, 119234 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jun 26; Vol. 23 (13). Date of Electronic Publication: 2022 Jun 26.
Typ publikacji:
Journal Article
MeSH Terms:
Histones*/metabolism
Nucleosomes*
Adenosine Diphosphate ; DNA/chemistry ; Humans ; Kinetics ; NAD/metabolism ; Poly (ADP-Ribose) Polymerase-1/metabolism ; Transcription, Genetic
Czasopismo naukowe
Tytuł:
Mechanisms of Nucleosome Reorganization by PARP1.
Autorzy:
Maluchenko NV; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.
Nilov DK; Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.
Pushkarev SV; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119991 Moscow, Russia.
Kotova EY; Fox Chase Cancer Center, Philadelphia, PA 19111-2497, USA.
Gerasimova NS; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.
Kirpichnikov MP; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.
Langelier MF; Department of Biochemistry and Molecular Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, QC H3T 1J4, Canada.
Pascal JM; Department of Biochemistry and Molecular Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, QC H3T 1J4, Canada.
Akhtar MS; Molecular and Structural Biology Division, CSIR-Central Drug Research Institute, Lucknow 226031, Uttar Pradesh, India.
Feofanov AV; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Studitsky VM; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.; Fox Chase Cancer Center, Philadelphia, PA 19111-2497, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 09; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 09.
Typ publikacji:
Journal Article
MeSH Terms:
Chromatin/*genetics
DNA-Binding Proteins/*genetics
Nucleosomes/*genetics
Poly (ADP-Ribose) Polymerase-1/*genetics
DNA Repair/genetics ; Gene Expression Regulation/genetics ; Histones/genetics ; Humans ; Molecular Dynamics Simulation ; Promoter Regions, Genetic/genetics
Czasopismo naukowe
Tytuł:
Structural basis for allosteric PARP-1 retention on DNA breaks.
Autorzy:
Zandarashvili L; Department of Biochemistry and Biophysics, Penn Center for Genome Integrity, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Langelier MF; Département de Biochimie and Médecine Moléculaire, Faculté de Médecine, Université de Montréal, Montréal, QC H3C 3J7, Canada.
Velagapudi UK; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY 11439, USA.
Hancock MA; SPR-MS Facility, McGill University, Montréal, Quebec, Canada.
Steffen JD; Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Billur R; Department of Biochemistry and Biophysics, Penn Center for Genome Integrity, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Hannan ZM; Department of Biochemistry and Biophysics, Penn Center for Genome Integrity, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Wicks AJ; CRUK Gene Function Laboratory and Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London SW3 6JB, UK.
Krastev DB; CRUK Gene Function Laboratory and Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London SW3 6JB, UK.
Pettitt SJ; CRUK Gene Function Laboratory and Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London SW3 6JB, UK.
Lord CJ; CRUK Gene Function Laboratory and Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London SW3 6JB, UK.
Talele TT; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY 11439, USA.
Pascal JM; Département de Biochimie and Médecine Moléculaire, Faculté de Médecine, Université de Montréal, Montréal, QC H3C 3J7, Canada. .
Black BE; Department of Biochemistry and Biophysics, Penn Center for Genome Integrity, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. .
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Źródło:
Science (New York, N.Y.) [Science] 2020 Apr 03; Vol. 368 (6486).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Allosteric Regulation/*drug effects
DNA Breaks/*drug effects
DNA Damage/*drug effects
Neoplasms/*enzymology
Poly (ADP-Ribose) Polymerase-1/*chemistry
Poly(ADP-ribose) Polymerase Inhibitors/*chemistry
Benzimidazoles/chemistry ; Benzimidazoles/pharmacology ; Cell Line, Tumor ; Humans ; Isoindoles/chemistry ; Isoindoles/pharmacology ; Piperazines/chemistry ; Piperazines/pharmacology ; Poly(ADP-ribose) Polymerase Inhibitors/pharmacology ; Protein Domains
Czasopismo naukowe
Tytuł:
Unfolding of core nucleosomes by PARP-1 revealed by spFRET microscopy.
Autorzy:
Sultanov DC; Biology Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia.; Fox Chase Cancer Center, Philadelphia, PA, 19111-2497, USA.
Gerasimova NS; Biology Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia.
Kudryashova KS; Biology Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of Russian Academy of Sciences, 117997 Moscow, Russia.
Maluchenko NV; Biology Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia.
Kotova EY; Fox Chase Cancer Center, Philadelphia, PA, 19111-2497, USA.
Langelier MF; Department of Biochemistry and Molecular Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montréal, QC H3T 1J4, Canada.
Pascal JM; Department of Biochemistry and Molecular Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montréal, QC H3T 1J4, Canada.
Kirpichnikov MP; Fox Chase Cancer Center, Philadelphia, PA, 19111-2497, USA.
Feofanov AV; Biology Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of Russian Academy of Sciences, 117997 Moscow, Russia.
Studitsky VM; Biology Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia.; Fox Chase Cancer Center, Philadelphia, PA, 19111-2497, USA.
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Źródło:
AIMS genetics [AIMS Genet] 2017; Vol. 4 (1), pp. 21-31. Date of Electronic Publication: 2017 Jan 05.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
A PARP1-ERK2 synergism is required for the induction of LTP.
Autorzy:
Visochek L; Neufeld Cardiac Research institute, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel.
Grigoryan G; Department of Neurobiology, the Weizmann Institute of Science, Rehovot 76100, Israel.
Kalal A; Neufeld Cardiac Research institute, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel.; Department of Physiology and Pharmacology, Tel-Aviv University, Tel-Aviv 69978, Israel.
Milshtein-Parush H; Department of Physiology and Pharmacology, Tel-Aviv University, Tel-Aviv 69978, Israel.; Sagol School of Neuroscience, Tel-Aviv University, Tel-Aviv 69978, Israel.
Gazit N; Department of Physiology and Pharmacology, Tel-Aviv University, Tel-Aviv 69978, Israel.; Sagol School of Neuroscience, Tel-Aviv University, Tel-Aviv 69978, Israel.
Slutsky I; Department of Physiology and Pharmacology, Tel-Aviv University, Tel-Aviv 69978, Israel.; Sagol School of Neuroscience, Tel-Aviv University, Tel-Aviv 69978, Israel.
Yeheskel A; Bioinformatics Unit, George S. Wise Faculty of Life Sciences, Tel-Aviv University, Tel-Aviv 69978, Israel.
Shainberg A; Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, 52900 Ramat Gan, Israel.
Castiel A; Cancer Research Center, Sheba Medical Center, 53621 Ramat Gan, Israel.
Seger R; Department of Biological Regulation, the Weizmann Institute of Science, Rehovot 76100, Israel.
Langelier MF; Department of Biochemistry and Molecular Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, USA.
Dantzer F; Biotechnology and Cell Signaling, UMR7242, Ecole Superieure de Biotechnologie Strasbourg, F-67400, Illkrich-Graffenstaden, France.
Pascal JM; Department of Biochemistry and Molecular Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, USA.
Segal M; Department of Neurobiology, the Weizmann Institute of Science, Rehovot 76100, Israel.
Cohen-Armon M; Neufeld Cardiac Research institute, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel.; Department of Physiology and Pharmacology, Tel-Aviv University, Tel-Aviv 69978, Israel.; Sagol School of Neuroscience, Tel-Aviv University, Tel-Aviv 69978, Israel.
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Źródło:
Scientific reports [Sci Rep] 2016 Apr 28; Vol. 6, pp. 24950. Date of Electronic Publication: 2016 Apr 28.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation*
Long-Term Potentiation*
CA1 Region, Hippocampal/*physiology
CA3 Region, Hippocampal/*physiology
Mitogen-Activated Protein Kinase 1/*metabolism
Poly (ADP-Ribose) Polymerase-1/*metabolism
Animals ; Mice ; Mice, Knockout ; Protein Binding
Czasopismo naukowe
Tytuł:
Structural basis for DNA damage-dependent poly(ADP-ribosyl)ation by human PARP-1.
Autorzy:
Langelier MF; Department of Biochemistry and Molecular Biology, The Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Planck JL
Roy S
Pascal JM
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Źródło:
Science (New York, N.Y.) [Science] 2012 May 11; Vol. 336 (6082), pp. 728-32.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Breaks, Double-Stranded*
DNA/*chemistry
DNA/*metabolism
Poly Adenosine Diphosphate Ribose/*metabolism
Poly(ADP-ribose) Polymerases/*chemistry
Poly(ADP-ribose) Polymerases/*metabolism
Catalytic Domain ; Crystallography, X-Ray ; Enzyme Stability ; Humans ; Hydrophobic and Hydrophilic Interactions ; Models, Molecular ; Nucleic Acid Conformation ; Poly (ADP-Ribose) Polymerase-1 ; Protein Binding ; Protein Conformation ; Protein Structure, Tertiary
Czasopismo naukowe
Tytuł:
Functional dissection of the catalytic mechanism of mammalian RNA polymerase II.
Autorzy:
Coulombe B; Gene Transcription Laboratory, Institute de recherche cliniques de Montréal, QC, Canada. />Langelier MF
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Źródło:
Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2005 Aug; Vol. 83 (4), pp. 497-504.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Mutation*
Transcription, Genetic*
RNA Polymerase II/*isolation & purification
RNA Polymerase II/*metabolism
Animals ; Catalysis ; Humans ; Peptide Elongation Factors/physiology ; RNA Polymerase II/genetics ; Transcription Factors, TFII/genetics ; Transcription Factors, TFII/isolation & purification ; Transcription Factors, TFII/metabolism
Czasopismo naukowe
    Wyświetlanie 1-9 z 9

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