Genetic investigation into the broad health implications of caffeine: evidence from phenome-wide, proteome-wide and metabolome-wide Mendelian randomization.
Autorzy:
Zagkos L; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. Cronjé HT; Department of Public Health, Section of Epidemiology, University of Copenhagen, Copenhagen, Denmark. Woolf B; School of Psychological Science, University of Bristol, Bristol, UK.; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Medical Research Council Biostatistics Unit at the University of Cambridge, Cambridge, UK. de La Harpe R; Unit of Internal Medicine, Department of Medicine, University Hospital of Lausanne, Lausanne, Switzerland. Burgess S; Medical Research Council Biostatistics Unit at the University of Cambridge, Cambridge, UK. Mantzoros CS; Department of Medicine, Boston VA Healthcare System and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA. Elliott P; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; United Kingdom Dementia Research Institute at Imperial College London, London, UK.; British Heart Foundation Centre for Research Excellence, Imperial College London, London, UK. Yuan S; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden. LarssonSC; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden.; Unit of Medical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. Tzoulaki I; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; United Kingdom Dementia Research Institute at Imperial College London, London, UK.; British Heart Foundation Centre for Research Excellence, Imperial College London, London, UK.; Division of Systems Biology, Biomedical Research Foundation of the Academy of Athens, Athens, Greece. Gill D; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. .; British Heart Foundation Centre for Research Excellence, Imperial College London, London, UK. .
Pokaż więcej
Źródło:
BMC medicine [BMC Med] 2024 Feb 20; Vol. 22 (1), pp. 81. Date of Electronic Publication: 2024 Feb 20.
Declining hip fracture burden in Sweden 1998-2019 and consequences for projections through 2050.
Autorzy:
Michaëlsson K; Department of Surgical Sciences, Uppsala University, 751 85, Uppsala, Sweden. . Baron JA; Department of Surgical Sciences, Uppsala University, 751 85, Uppsala, Sweden.; Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA.; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. Byberg L; Department of Surgical Sciences, Uppsala University, 751 85, Uppsala, Sweden. LarssonSC; Department of Surgical Sciences, Uppsala University, 751 85, Uppsala, Sweden.; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Melhus H; Department of Medical Sciences, Uppsala University, Uppsala, Sweden. Gedeborg R; Department of Surgical Sciences, Uppsala University, 751 85, Uppsala, Sweden.
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2024 Jan 06; Vol. 14 (1), pp. 706. Date of Electronic Publication: 2024 Jan 06.
Proteomic insights into the associations between obesity, lifestyle factors, and coronary artery disease.
Autorzy:
Yang F; Department of Cardiology, First Affiliated Hospital of Ningbo University (Ningbo First Hospital), School of Medicine, Ningbo University, 59 Liuting Road, Ningbo, 315010, China.; Key Laboratory of Precision Medicine for Atherosclerotic Diseases of Zhejiang Province, Ningbo, China.; Cardiovascular Disease Clinical Medical Research Center of Ningbo, Ningbo, Zhejiang, China. Xu F; Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China. Zhang H; Department of Big Data in Health Science School of Public Health, Center of Clinical Big Data and Analytics of The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. Gill D; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. LarssonSC; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Unit of Medical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. Li X; Department of Big Data in Health Science School of Public Health, Center of Clinical Big Data and Analytics of The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. . Cui H; Department of Cardiology, First Affiliated Hospital of Ningbo University (Ningbo First Hospital), School of Medicine, Ningbo University, 59 Liuting Road, Ningbo, 315010, China. hbcui_.; Key Laboratory of Precision Medicine for Atherosclerotic Diseases of Zhejiang Province, Ningbo, China. hbcui_.; Cardiovascular Disease Clinical Medical Research Center of Ningbo, Ningbo, Zhejiang, China. hbcui_. Yuan S; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. .
Pokaż więcej
Źródło:
BMC medicine [BMC Med] 2023 Dec 05; Vol. 21 (1), pp. 485. Date of Electronic Publication: 2023 Dec 05.
Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome.
Autorzy:
Sun J; Department of Big Data in Health Science School of Public Health, and Center of Clinical Big Data and Analytics of The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Zhao J; Department of Big Data in Health Science School of Public Health, and Center of Clinical Big Data and Analytics of The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Jiang F; Department of Big Data in Health Science School of Public Health, and Center of Clinical Big Data and Analytics of The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Wang L; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK. Xiao Q; Colorectal Surgery and Oncology, Key Laboratory of Cancer Prevention and Intervention, Ministry of Education, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. Han F; Department of Pathology and Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Chen J; Department of Big Data in Health Science School of Public Health, and Center of Clinical Big Data and Analytics of The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Yuan S; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Wei J; Colorectal Surgery and Oncology, Key Laboratory of Cancer Prevention and Intervention, Ministry of Education, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. LarssonSC; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Unit of Medical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. Zhang H; Department of Pathology and Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Dunlop MG; Cancer Research UK Edinburgh Centre, Medical Research Council Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.; Colon Cancer Genetics Group, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK. Farrington SM; Cancer Research UK Edinburgh Centre, Medical Research Council Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK. Ding K; Colorectal Surgery and Oncology, Key Laboratory of Cancer Prevention and Intervention, Ministry of Education, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. Theodoratou E; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.; Cancer Research UK Edinburgh Centre, Medical Research Council Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK. Li X; Department of Big Data in Health Science School of Public Health, and Center of Clinical Big Data and Analytics of The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. .; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK. .
Pokaż więcej
Źródło:
Genome medicine [Genome Med] 2023 Sep 19; Vol. 15 (1), pp. 75. Date of Electronic Publication: 2023 Sep 19.
Typ publikacji:
Meta-Analysis; Journal Article; Research Support, Non-U.S. Gov't
Appraising the causal relationship between plasma caffeine levels and neuropsychiatric disorders through Mendelian randomization.
Autorzy:
Woolf B; School of Psychological Science, University of Bristol, Bristol, UK.; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; MRC Biostatistics Unit at the University of Cambridge, Cambridge, UK. Cronjé HT; Department of Public Health, Section of Epidemiology, University of Copenhagen, Copenhagen, Denmark. Zagkos L; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. Burgess S; MRC Biostatistics Unit at the University of Cambridge, Cambridge, UK. Gill D; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. LarssonSC; Unit of Medical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. susanna.larsson@uu.se.; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. susanna.larsson@uu.se.
Pokaż więcej
Źródło:
BMC medicine [BMC Med] 2023 Aug 08; Vol. 21 (1), pp. 296. Date of Electronic Publication: 2023 Aug 08.
Typ publikacji:
Meta-Analysis; Journal Article; Research Support, Non-U.S. Gov't
Sleep duration and daytime napping in relation to incident inflammatory bowel disease: a prospective cohort study.
Autorzy:
Yuan S; Department of Big Data in Health Science, School of Public Health and The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Sun Y; Centre for Global Health, School of Public Health, Zhejiang University School of Medicine, Hangzhou, China. Tan X; Unit of Functional Pharmacology and neuroscience, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. Geng J; Centre for Global Health, School of Public Health, Zhejiang University School of Medicine, Hangzhou, China. Sun J; Department of Big Data in Health Science, School of Public Health and The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. Chen X; Department of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, China. Yu L; Department of Big Data in Health Science, School of Public Health and The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. Wang J; Department of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, China. Zhou X; Department of Big Data in Health Science, School of Public Health and The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. Hesketh T; Centre for Global Health, School of Public Health, Zhejiang University School of Medicine, Hangzhou, China.; Institute for Global Health, University College London, London, UK. LarssonSC; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Unit of Medical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. Chen J; Centre for Global Health, School of Public Health, Zhejiang University School of Medicine, Hangzhou, China.; Department of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, China. Wang X; Department of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, China. Li X; Department of Big Data in Health Science, School of Public Health and The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. Liu Z; Center for IBD Research, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Antioxidants, minerals and vitamins in relation to Crohn's disease and ulcerative colitis: A Mendelian randomization study.
Autorzy:
Chen J; Department of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, China.; Centre for Global Health, Zhejiang University School of Medicine, Hangzhou, China.; Department of Big Data in Health Science, School of Public Health and The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Ruan X; Department of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, China. Yuan S; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Deng M; Department of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, China. Zhang H; Department of Big Data in Health Science, School of Public Health and The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Sun J; Department of Big Data in Health Science, School of Public Health and The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Yu L; Department of Big Data in Health Science, School of Public Health and The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Satsangi J; Translational Gastroenterology Unit, Nuffield Department of Medicine, Experimental Medicine Division, University of Oxford, John Radcliffe Hospital, Oxford, UK. LarssonSC; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Unit of Medical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. Therdoratou E; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.; Cancer Research UK Edinburgh Centre, Medical Research Council Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK. Wang X; Department of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, China. Li X; Department of Big Data in Health Science, School of Public Health and The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
A Mendelian randomization study of genetic predisposition to autoimmune diseases and COVID-19.
Autorzy:
Li S; Clinical Epidemiology and EBM Unit, Beijing Friendship Hospital, Capital Medical University, Beijing Clinical Research Institute, Beijing, China.; National Clinical Research Center for Digestive Diseases, Beijing, China.; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 7 Sassoon Rd, Hong Kong, China. Yuan S; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Nobelsväg 13, 17177, Stockholm, Sweden. Schooling CM; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 7 Sassoon Rd, Hong Kong, China.; School of Public Health and Health Policy, The City University of New York, 55 W 125 St, New York, NY, 10027, USA. LarssonSC; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Nobelsväg 13, 17177, Stockholm, Sweden. susanna.larsson@surgsci.uu.se.; Department of Surgical Sciences, Uppsala University, Dag Hammarskjölds Väg 14B, Uppsala, Sweden. susanna.larsson@surgsci.uu.se.
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2022 Oct 21; Vol. 12 (1), pp. 17703. Date of Electronic Publication: 2022 Oct 21.
Genetically predicted cortisol levels and risk of venous thromboembolism.
Autorzy:
Allara E; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom. Lee WH; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom. Burgess S; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; MRC Biostatistics Unit, University of Cambridge, Cambridge, United Kingdom. LarssonSC; Unit of Medical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies
