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    Wyświetlanie 1-15 z 15
    Tytuł:
    An Update on the Therapeutic Potential of Antimicrobial Peptides against Acinetobacter baumannii Infections.
    Autorzy:
    Rangel K; Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), Oswaldo Cruz Institut, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.; Epidemiology and Molecular Systematics Laboratory (LEMS), Oswaldo Cruz Institut, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.
    Lechuga GC; Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), Oswaldo Cruz Institut, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.; Epidemiology and Molecular Systematics Laboratory (LEMS), Oswaldo Cruz Institut, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.
    Provance DW Jr; Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), Oswaldo Cruz Institut, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.; Epidemiology and Molecular Systematics Laboratory (LEMS), Oswaldo Cruz Institut, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.
    Morel CM; Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), Oswaldo Cruz Institut, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.
    De Simone SG; Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), Oswaldo Cruz Institut, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.; Epidemiology and Molecular Systematics Laboratory (LEMS), Oswaldo Cruz Institut, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.; Program of Post-Graduation on Science and Biotechnology, Department of Molecular and Cellular Biology, Biology Institute, Federal Fluminense University, Niterói 22040-036, RJ, Brazil.; Program of Post-Graduation on Parasitic Biology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.
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    Źródło:
    Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2023 Sep 11; Vol. 16 (9). Date of Electronic Publication: 2023 Sep 11.
    Typ publikacji:
    Journal Article; Review
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    High-Throughput IgG Epitope Mapping of Tetanus Neurotoxin: Implications for Immunotherapy and Vaccine Design.
    Autorzy:
    De-Simone SG; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Diseases of Neglected Populations (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.; Laboratory of Epidemiology and Molecular Systematics (LESM), Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.; Post-Graduation Program in Science and Biotechnology, Department of Molecular and Cellular Biology, Biology Institute, Federal Fluminense University, Niterói 22040-036, RJ, Brazil.
    Napoleão-Pêgo P; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Diseases of Neglected Populations (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.; Laboratory of Epidemiology and Molecular Systematics (LESM), Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.
    Lechuga GC; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Diseases of Neglected Populations (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.; Laboratory of Epidemiology and Molecular Systematics (LESM), Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.
    Carvalho JPRS; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Diseases of Neglected Populations (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.; Laboratory of Epidemiology and Molecular Systematics (LESM), Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.; Post-Graduation Program in Science and Biotechnology, Department of Molecular and Cellular Biology, Biology Institute, Federal Fluminense University, Niterói 22040-036, RJ, Brazil.
    Gomes LR; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Diseases of Neglected Populations (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.; Laboratory of Epidemiology and Molecular Systematics (LESM), Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.
    Cardozo SV; Department of Health, Graduate Program in Translational Biomedicine (BIOTRANS), University of Grande Rio (UNIGRANRIO), Caxias 25071-202, RJ, Brazil.
    Morel CM; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Diseases of Neglected Populations (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.
    Provance DW Jr; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Diseases of Neglected Populations (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.; Laboratory of Epidemiology and Molecular Systematics (LESM), Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.
    Silva FRD; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Diseases of Neglected Populations (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.; Laboratory of Epidemiology and Molecular Systematics (LESM), Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.
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    Źródło:
    Toxins [Toxins (Basel)] 2023 Mar 24; Vol. 15 (4). Date of Electronic Publication: 2023 Mar 24.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Epitopes, B-Lymphocyte*
    Tetanus*/prevention & control
    Humans ; Child ; Epitope Mapping ; Peptides ; Vaccination ; Immunoglobulin G
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    B-Cell Epitope Mapping of the Vibrio cholera Toxins A, B, and P and an ELISA Assay.
    Autorzy:
    De-Simone SG; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Neglected Diseases Populations (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.; Epidemiology and Molecular Systematics Laboratory (LEMS), Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.; Program of Post-Graduation on Science and Biotechnology, Molecular and Cellular Biology Department, Biology Institute, Federal Fluminense University, Niterói 24020-036, RJ, Brazil.
    Napoleão-Pêgo P; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Neglected Diseases Populations (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.; Epidemiology and Molecular Systematics Laboratory (LEMS), Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.
    Gonçalves PS; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Neglected Diseases Populations (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.; Epidemiology and Molecular Systematics Laboratory (LEMS), Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.; Program of Post-Graduation on Science and Biotechnology, Molecular and Cellular Biology Department, Biology Institute, Federal Fluminense University, Niterói 24020-036, RJ, Brazil.
    Lechuga GC; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Neglected Diseases Populations (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.; Epidemiology and Molecular Systematics Laboratory (LEMS), Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.
    Cardoso SV; Department of Health, Graduate Program in Translational Biomedicine (BIOTRANS), University of Grande Rio (UNIGRANRIO), Caxias 25071-202, RJ, Brazil.
    Provance DW Jr; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Neglected Diseases Populations (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.; Epidemiology and Molecular Systematics Laboratory (LEMS), Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.
    Morel CM; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Neglected Diseases Populations (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.
    da Silva FR; Center for Technological Development in Health (CDTS)/National Institute of Science and Technology for Innovation in Neglected Diseases Populations (INCT-IDPN), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.; Epidemiology and Molecular Systematics Laboratory (LEMS), Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro 21040-900, RJ, Brazil.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2022 Dec 28; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 28.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Vibrio cholerae*/metabolism
    Cholera*
    Cholera Vaccines*
    Animals ; Mice ; Cholera Toxin/metabolism ; Epitopes, B-Lymphocyte ; Epitope Mapping ; Enzyme-Linked Immunosorbent Assay ; Antibodies, Bacterial
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Potent Activity of a High Concentration of Chemical Ozone against Antibiotic-Resistant Bacteria.
    Autorzy:
    Rangel K; Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, Brazil.; Laboratory of Epidemiology and Molecular Systematics (LESM), Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-900, Brazil.
    Cabral FO; Microbiology Department, National Institute for Quality Control in Health (INCQS), FIOCRUZ, Rio de Janeiro 21040-900, Brazil.
    Lechuga GC; Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, Brazil.; Laboratory of Epidemiology and Molecular Systematics (LESM), Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-900, Brazil.
    Carvalho JPRS; Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, Brazil.; Laboratory of Epidemiology and Molecular Systematics (LESM), Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-900, Brazil.; Post-Graduation Program in Science and Biotechnology, Department of Molecular and Cellular Biology, Biology Institute, Federal Fluminense University, Niterói 22040-036, Brazil.
    Villas-Bôas MHS; Microbiology Department, National Institute for Quality Control in Health (INCQS), FIOCRUZ, Rio de Janeiro 21040-900, Brazil.
    Midlej V; Laboratory of Cellular and Ultrastructure, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-900, Brazil.
    De-Simone SG; Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, Brazil.; Laboratory of Epidemiology and Molecular Systematics (LESM), Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-900, Brazil.; Post-Graduation Program in Science and Biotechnology, Department of Molecular and Cellular Biology, Biology Institute, Federal Fluminense University, Niterói 22040-036, Brazil.
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    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2022 Jun 22; Vol. 27 (13). Date of Electronic Publication: 2022 Jun 22.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Cross Infection*/microbiology
    Ozone*/pharmacology
    COVID-19 Drug Treatment*
    Anti-Bacterial Agents/pharmacology ; Bacteria ; Humans ; Pseudomonas aeruginosa ; SARS-CoV-2 ; Staphylococcus aureus
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Bioactivity of Novel Pyrazole-Thiazolines Scaffolds against Trypanosoma cruzi : Computational Approaches and 3D Spheroid Model on Drug Discovery for Chagas Disease.
    Autorzy:
    Lara LDS; Laboratório de Ultraestrutura Celular, Instituto Oswaldo Cruz, Fiocruz, Av. Brasil 4365, Manguinhos, Rio de Janeiro 21040-900, Brazil.
    Lechuga GC; Laboratório de Ultraestrutura Celular, Instituto Oswaldo Cruz, Fiocruz, Av. Brasil 4365, Manguinhos, Rio de Janeiro 21040-900, Brazil.
    Orlando LMR; Laboratório de Ultraestrutura Celular, Instituto Oswaldo Cruz, Fiocruz, Av. Brasil 4365, Manguinhos, Rio de Janeiro 21040-900, Brazil.
    Ferreira BS; Laboratório de Síntese de Sistemas Heterocíclicos (LaSSH), Instituto de Física e Química, Universidade Federal de Itajubá, Avenida BPS, 1303, Pinheirinho, Itajubá 37500-903, Brazil.
    Souto BA; Laboratório de Síntese de Sistemas Heterocíclicos (LaSSH), Instituto de Física e Química, Universidade Federal de Itajubá, Avenida BPS, 1303, Pinheirinho, Itajubá 37500-903, Brazil.
    Dos Santos MS; Laboratório de Síntese de Sistemas Heterocíclicos (LaSSH), Instituto de Física e Química, Universidade Federal de Itajubá, Avenida BPS, 1303, Pinheirinho, Itajubá 37500-903, Brazil.
    Pereira MCS; Laboratório de Ultraestrutura Celular, Instituto Oswaldo Cruz, Fiocruz, Av. Brasil 4365, Manguinhos, Rio de Janeiro 21040-900, Brazil.
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    Źródło:
    Pharmaceutics [Pharmaceutics] 2022 May 05; Vol. 14 (5). Date of Electronic Publication: 2022 May 05.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    New Insights into Hemopexin-Binding to Hemin and Hemoglobin.
    Autorzy:
    Lechuga GC; Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Population Diseases (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.; Laboratory of Epidemiology and Molecular Systematics (LESM), Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.
    Napoleão-Pêgo P; Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Population Diseases (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.; Laboratory of Epidemiology and Molecular Systematics (LESM), Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.
    Morel CM; Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Population Diseases (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.
    Provance DW; Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Population Diseases (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.; Laboratory of Epidemiology and Molecular Systematics (LESM), Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.
    De-Simone SG; Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Population Diseases (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.; Laboratory of Epidemiology and Molecular Systematics (LESM), Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.; Department of Cellular and Molecular Biology, Biology Institute, Federal Fluminense University, Niterói 24020-141, RJ, Brazil.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2022 Mar 30; Vol. 23 (7). Date of Electronic Publication: 2022 Mar 30.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Hemin*/metabolism
    Hemopexin*/metabolism
    Ferric Compounds ; Heme/metabolism ; Hemoglobins/metabolism ; Hemolysis ; Histidine ; Humans ; Molecular Docking Simulation
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Angiostrongylus cantonensis an Atypical Presenilin: Epitope Mapping, Characterization, and Development of an ELISA Peptide Assay for Specific Diagnostic of Angiostrongyliasis.
    Autorzy:
    De-Simone SG; Center of Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Diseases (INCT-IDN), FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.; Laboratory of Epidemiology and Molecular Systematics (LESM), Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.; Department of Cellular and Molecular Biology, Biology Institute, Federal Fluminense University, Niterói 24220-900, RJ, Brazil.
    Napoleão-Pêgo P; Center of Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Diseases (INCT-IDN), FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.
    Gonçalves PS; Center of Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Diseases (INCT-IDN), FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.; Department of Cellular and Molecular Biology, Biology Institute, Federal Fluminense University, Niterói 24220-900, RJ, Brazil.
    Lechuga GC; Center of Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Diseases (INCT-IDN), FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.
    Mandonado A Jr; Laboratory of Biology and Parasitology of Wild Mammals Reservoirs, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, RJ, Brazil.
    Graeff-Teixeira C; Infectious Diseases Unit, Department of Pathology, Federal University of Espirito Santo, Vitória 29075-910, ES, Brazil.
    Provance DW Jr; Center of Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Diseases (INCT-IDN), FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.
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    Źródło:
    Membranes [Membranes (Basel)] 2022 Jan 19; Vol. 12 (2). Date of Electronic Publication: 2022 Jan 19.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Structural Optimization and Biological Activity of Pyrazole Derivatives: Virtual Computational Analysis, Recovery Assay and 3D Culture Model as Potential Predictive Tools of Effectiveness against Trypanosoma cruzi .
    Autorzy:
    Orlando LMR; Laboratório de Ultraestrutura Celular, Instituto Oswaldo Cruz, Fiocruz, Av. Brasil 4365, Manguinhos, Rio de Janeiro 21040-900, RJ, Brazil.
    Lechuga GC; Laboratório de Ultraestrutura Celular, Instituto Oswaldo Cruz, Fiocruz, Av. Brasil 4365, Manguinhos, Rio de Janeiro 21040-900, RJ, Brazil.
    da Silva Lara L; Laboratório de Ultraestrutura Celular, Instituto Oswaldo Cruz, Fiocruz, Av. Brasil 4365, Manguinhos, Rio de Janeiro 21040-900, RJ, Brazil.
    Ferreira BS; Laboratório de Síntese de Sistemas Heterocíclicos (LaSSH), Instituto de Física e Química (IFQ), Universidade Federal de Itajubá, Av. BPS 1303, Pinheirinho, Itajubá 37500-903, MG, Brazil.
    Pereira CN; Laboratório de Síntese de Sistemas Heterocíclicos (LaSSH), Instituto de Física e Química (IFQ), Universidade Federal de Itajubá, Av. BPS 1303, Pinheirinho, Itajubá 37500-903, MG, Brazil.
    Silva RC; Laboratório de Síntese de Sistemas Heterocíclicos (LaSSH), Instituto de Física e Química (IFQ), Universidade Federal de Itajubá, Av. BPS 1303, Pinheirinho, Itajubá 37500-903, MG, Brazil.
    Dos Santos MS; Laboratório de Síntese de Sistemas Heterocíclicos (LaSSH), Instituto de Física e Química (IFQ), Universidade Federal de Itajubá, Av. BPS 1303, Pinheirinho, Itajubá 37500-903, MG, Brazil.
    Pereira MCS; Laboratório de Ultraestrutura Celular, Instituto Oswaldo Cruz, Fiocruz, Av. Brasil 4365, Manguinhos, Rio de Janeiro 21040-900, RJ, Brazil.
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    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2021 Nov 08; Vol. 26 (21). Date of Electronic Publication: 2021 Nov 08.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Cell Culture Techniques*
    Printing, Three-Dimensional*
    Chagas Disease/*drug therapy
    Pyrazoles/*pharmacology
    Trypanocidal Agents/*pharmacology
    Trypanosoma cruzi/*drug effects
    Humans ; Models, Molecular ; Parasitic Sensitivity Tests ; Pyrazoles/chemistry ; Trypanocidal Agents/chemistry
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    SARS-CoV-2 Proteins Bind to Hemoglobin and Its Metabolites.
    Autorzy:
    Lechuga GC; FIOCRUZ, Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Population Diseases (INCT-IDPN), Rio de Janeiro 21040-900, RJ, Brazil.; Laboratory of Celular Ultrastructure, FIOCRUZ, Oswaldo Cruz Institute, Rio de Janeiro 21040-900, RJ, Brazil.
    Souza-Silva F; FIOCRUZ, Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Population Diseases (INCT-IDPN), Rio de Janeiro 21040-900, RJ, Brazil.; Biology and Heath Science Faculty, Iguaçu University, Nova Iguaçu 26260-045, RJ, Brazil.
    Sacramento CQ; FIOCRUZ, Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Population Diseases (INCT-IDPN), Rio de Janeiro 21040-900, RJ, Brazil.; Laboratory of Immunopharmacology, FIOCRUZ, Oswaldo Cruz Institute, Rio de Janeiro 21040-900, RJ, Brazil.
    Trugilho MRO; FIOCRUZ, Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Population Diseases (INCT-IDPN), Rio de Janeiro 21040-900, RJ, Brazil.; Laboratory of Toxinology, FIOCRUZ, Oswaldo Cruz Institute, Rio de Janeiro 21040-900, RJ, Brazil.
    Valente RH; Laboratory of Toxinology, FIOCRUZ, Oswaldo Cruz Institute, Rio de Janeiro 21040-900, RJ, Brazil.
    Napoleão-Pêgo P; FIOCRUZ, Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Population Diseases (INCT-IDPN), Rio de Janeiro 21040-900, RJ, Brazil.
    Dias SSG; Laboratory of Immunopharmacology, FIOCRUZ, Oswaldo Cruz Institute, Rio de Janeiro 21040-900, RJ, Brazil.
    Fintelman-Rodrigues N; FIOCRUZ, Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Population Diseases (INCT-IDPN), Rio de Janeiro 21040-900, RJ, Brazil.; Laboratory of Immunopharmacology, FIOCRUZ, Oswaldo Cruz Institute, Rio de Janeiro 21040-900, RJ, Brazil.
    Temerozo JR; Laboratory of Thymus Research, FIOCRUZ, Oswaldo Cruz Institute, Rio de Janeiro 21040-900, RJ, Brazil.; FIOCRUZ, National Institute for Science and Technology on Neuroimmunomodulation (INCT/NIM), Rio de Janeiro 21040-900, RJ, Brazil.
    Carels N; FIOCRUZ, Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Population Diseases (INCT-IDPN), Rio de Janeiro 21040-900, RJ, Brazil.; Biology and Heath Science Faculty, Iguaçu University, Nova Iguaçu 26260-045, RJ, Brazil.
    Alves CR; Laboratory of Molecular Biology and Endemic Diseases, FIOCRUZ, Oswaldo Cruz Institute, Rio de Janeiro 21040-900, RJ, Brazil.
    Pereira MCS; Laboratory of Celular Ultrastructure, FIOCRUZ, Oswaldo Cruz Institute, Rio de Janeiro 21040-900, RJ, Brazil.
    Provance DW Jr; FIOCRUZ, Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Population Diseases (INCT-IDPN), Rio de Janeiro 21040-900, RJ, Brazil.
    Souza TML; FIOCRUZ, Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Population Diseases (INCT-IDPN), Rio de Janeiro 21040-900, RJ, Brazil.; Laboratory of Immunopharmacology, FIOCRUZ, Oswaldo Cruz Institute, Rio de Janeiro 21040-900, RJ, Brazil.
    De-Simone SG; FIOCRUZ, Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Population Diseases (INCT-IDPN), Rio de Janeiro 21040-900, RJ, Brazil.; Department of Cellular and Molecular Biology, Biology Institute, Federal Fluminense University, Niterói 24020-141, RJ, Brazil.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2021 Aug 21; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 21.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    COVID-19/*etiology
    Hemoglobins/*metabolism
    SARS-CoV-2/*metabolism
    Viral Nonstructural Proteins/*metabolism
    Viral Structural Proteins/*metabolism
    COVID-19/blood ; Hemin/metabolism ; Hemoglobins/ultrastructure ; Humans ; Molecular Docking Simulation ; Protein Binding ; Protein Domains ; Proteomics ; Protoporphyrins/metabolism ; SARS-CoV-2/pathogenicity ; Viral Nonstructural Proteins/ultrastructure ; Viral Structural Proteins/ultrastructure ; Virus Attachment ; Virus Replication
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Small Angle X-ray Scattering, Molecular Modeling, and Chemometric Studies from a Thrombin-Like (Lmr-47) Enzyme of Lachesis m. rhombeata Venom.
    Autorzy:
    De-Simone SG; FIOCRUZ, Center of Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Diseases Population (INCT-IDPN), Rio de Janeiro 21040-900, Brazil.; Department of Cellular and Molecular Biology, Biology Institute, Federal Fluminense University, Niterói 24020-141, Brazil.
    Lechuga GC; FIOCRUZ, Center of Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Diseases Population (INCT-IDPN), Rio de Janeiro 21040-900, Brazil.
    Napoleão-Pêgo P; FIOCRUZ, Center of Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Diseases Population (INCT-IDPN), Rio de Janeiro 21040-900, Brazil.
    Gomes LR; FIOCRUZ, Center of Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Diseases Population (INCT-IDPN), Rio de Janeiro 21040-900, Brazil.
    Provance DW Jr; FIOCRUZ, Center of Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Diseases Population (INCT-IDPN), Rio de Janeiro 21040-900, Brazil.; Interdisciplinary Medical Research Laboratory, Oswaldo Cruz Institute/FIOCRUZ, Rio de Janeiro 21040-900, Brazil.
    Nirello VD; Faculty of Pharmacy, Federal of Rio de Janeiro University, Rio de Janeiro 21949-900, Brazil.
    Sodero ACR; Faculty of Pharmacy, Federal of Rio de Janeiro University, Rio de Janeiro 21949-900, Brazil.
    Guedes HLM; Interdisciplinary Medical Research Laboratory, Oswaldo Cruz Institute/FIOCRUZ, Rio de Janeiro 21040-900, Brazil.; Laboratory of Immunopharmacology, Federal of Rio de Janeiro University, Duque de Caxias 25245-390, Brazil.
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    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2021 Jun 28; Vol. 26 (13). Date of Electronic Publication: 2021 Jun 28.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Crotalinae*
    Molecular Docking Simulation*
    Crotalid Venoms/*enzymology
    Reptilian Proteins/*chemistry
    Thrombin/*chemistry
    Animals ; Scattering, Small Angle ; X-Ray Diffraction
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Optimization of 1,4-Naphthoquinone Hit Compound: A Computational, Phenotypic, and In Vivo Screening against Trypanosoma cruzi .
    Autorzy:
    Lara LS; Laboratório de Ultraestrutura Celular, Instituto Oswaldo Cruz, Fiocruz, Av. Brasil 4365 Manguinhos, Rio de Janeiro 21040-900, RJ, Brazil.
    Lechuga GC; Laboratório de Ultraestrutura Celular, Instituto Oswaldo Cruz, Fiocruz, Av. Brasil 4365 Manguinhos, Rio de Janeiro 21040-900, RJ, Brazil.
    Moreira CDS; Departamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, Rua Outeiro São João Batista, Niterói 24020-141, Rio de Janeiro, Brazil.
    Santos TB; Departamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, Rua Outeiro São João Batista, Niterói 24020-141, Rio de Janeiro, Brazil.
    Ferreira VF; Departamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, Rua Outeiro São João Batista, Niterói 24020-141, Rio de Janeiro, Brazil.
    da Rocha DR; Departamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, Rua Outeiro São João Batista, Niterói 24020-141, Rio de Janeiro, Brazil.
    Pereira MCS; Laboratório de Ultraestrutura Celular, Instituto Oswaldo Cruz, Fiocruz, Av. Brasil 4365 Manguinhos, Rio de Janeiro 21040-900, RJ, Brazil.
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    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2021 Jan 15; Vol. 26 (2). Date of Electronic Publication: 2021 Jan 15.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Chagas Disease/*drug therapy
    Naphthoquinones/*chemistry
    Trypanocidal Agents/*pharmacology
    Trypanosoma cruzi/*drug effects
    Animals ; Chagas Disease/parasitology ; Computational Chemistry ; Male ; Mice ; Molecular Structure ; Naphthoquinones/pharmacology ; Parasitic Sensitivity Tests ; Structure-Activity Relationship ; Trypanocidal Agents/chemistry
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Trypanosoma cruzi Presenilin-Like Transmembrane Aspartyl Protease: Characterization and Cellular Localization.
    Autorzy:
    Lechuga GC; Center for Technological Development in Health/National Institute of Science and Technology for Innovation on Diseases of Neglected Population (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, Brazil.; Cellular Ultrastructure Laboratory, FIOCRUZ, Oswaldo Cruz Institute, Rio de Janeiro 21040-900, Brazil.
    Napoleão-Pêgo P; Center for Technological Development in Health/National Institute of Science and Technology for Innovation on Diseases of Neglected Population (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, Brazil.
    Bottino CCG; Center for Technological Development in Health/National Institute of Science and Technology for Innovation on Diseases of Neglected Population (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, Brazil.
    Pinho RT; Clinical Immunology Laboratory, FIOCRUZ, Oswaldo Cruz Institute, Rio de Janeiro 21040-900, Brazil.
    Provance-Jr DW; Center for Technological Development in Health/National Institute of Science and Technology for Innovation on Diseases of Neglected Population (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, Brazil.; Interdisciplinary Medical Research Laboratory, FIOCRUZ, Oswaldo Cruz Institute, Rio de Janeiro 21040-900, Brazil.
    De-Simone SG; Center for Technological Development in Health/National Institute of Science and Technology for Innovation on Diseases of Neglected Population (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, Brazil.; Department of Molecular and Cellular Biology, Federal Fluminense University, Niterói 24220-008, Brazil.
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    Źródło:
    Biomolecules [Biomolecules] 2020 Nov 17; Vol. 10 (11). Date of Electronic Publication: 2020 Nov 17.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Aspartic Acid Proteases/*metabolism
    Cell Membrane/*metabolism
    Pregnancy Proteins/*metabolism
    Presenilins/*metabolism
    Protozoan Proteins/*metabolism
    Trypanosoma cruzi/*metabolism
    Animals ; Aspartic Acid Proteases/analysis ; Aspartic Acid Proteases/genetics ; Cell Membrane/chemistry ; Cell Membrane/genetics ; Humans ; Phylogeny ; Pregnancy Proteins/analysis ; Pregnancy Proteins/genetics ; Presenilins/analysis ; Presenilins/genetics ; Protozoan Proteins/analysis ; Protozoan Proteins/genetics ; Rabbits ; Sequence Analysis, Protein ; Trypanosoma cruzi/chemistry ; Trypanosoma cruzi/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Heme metabolism as a therapeutic target against protozoan parasites.
    Autorzy:
    Lechuga GC; a Laboratório de Interação celular e molecular, Departamento de Biologia Celular e Molecular , Universidade Federal Fluminense, Rua Outeiro São João Batista , Rio de Janeiro , Brazil.; b Fundação Oswaldo Cruz , Laboratório de Ultraestrutura Celular , Rio de Janeiro , Brazil.; c Instituto de Biologia, Programa de Pós-graduação em Ciências e Biotecnologia (PPBI), Universidade Federal Fluminense , Rio de Janeiro , Brazil.
    Pereira MCS; b Fundação Oswaldo Cruz , Laboratório de Ultraestrutura Celular , Rio de Janeiro , Brazil.
    Bourguignon SC; a Laboratório de Interação celular e molecular, Departamento de Biologia Celular e Molecular , Universidade Federal Fluminense, Rua Outeiro São João Batista , Rio de Janeiro , Brazil.; c Instituto de Biologia, Programa de Pós-graduação em Ciências e Biotecnologia (PPBI), Universidade Federal Fluminense , Rio de Janeiro , Brazil.
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    Źródło:
    Journal of drug targeting [J Drug Target] 2019 Aug; Vol. 27 (7), pp. 767-779. Date of Electronic Publication: 2018 Oct 31.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Review
    MeSH Terms:
    Drug Delivery Systems*
    Antiparasitic Agents/*pharmacology
    Heme/*metabolism
    Parasitic Diseases/*drug therapy
    Biological Transport/drug effects ; Biological Transport/physiology ; Humans
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Heme crystallization in a Chagas disease vector acts as a redox-protective mechanism to allow insect reproduction and parasite infection.
    Autorzy:
    Ferreira CM; Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.; Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular (INCT-EM), Rio de Janeiro, Rio de Janeiro, Brazil.
    Stiebler R; Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.; Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular (INCT-EM), Rio de Janeiro, Rio de Janeiro, Brazil.; Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil.
    Saraiva FM; Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular (INCT-EM), Rio de Janeiro, Rio de Janeiro, Brazil.; Instituto de Biologia Roberto Alcântara Gomes, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
    Lechuga GC; Departamento de Biologia Celular e Molecular, Universidade Federal Fluminense, Niterói, Rio de Janeiro, Brazil.
    Walter-Nuno AB; Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.; Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular (INCT-EM), Rio de Janeiro, Rio de Janeiro, Brazil.
    Bourguignon SC; Departamento de Biologia Celular e Molecular, Universidade Federal Fluminense, Niterói, Rio de Janeiro, Brazil.
    Gonzalez MS; Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular (INCT-EM), Rio de Janeiro, Rio de Janeiro, Brazil.; Departamento de Biologia Geral, Universidade Federal Fluminense, Niterói, Rio de Janeiro, Brazil.
    Azambuja P; Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular (INCT-EM), Rio de Janeiro, Rio de Janeiro, Brazil.; Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil.
    Gandara ACP; Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.; Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular (INCT-EM), Rio de Janeiro, Rio de Janeiro, Brazil.
    Menna-Barreto RFS; Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil.
    Paiva-Silva GO; Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.; Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular (INCT-EM), Rio de Janeiro, Rio de Janeiro, Brazil.
    Paes MC; Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular (INCT-EM), Rio de Janeiro, Rio de Janeiro, Brazil.; Instituto de Biologia Roberto Alcântara Gomes, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
    Oliveira MF; Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.; Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular (INCT-EM), Rio de Janeiro, Rio de Janeiro, Brazil.
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    Źródło:
    PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2018 Jul 23; Vol. 12 (7), pp. e0006661. Date of Electronic Publication: 2018 Jul 23 (Print Publication: 2018).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chagas Disease/*parasitology
    Heme/*chemistry
    Insect Vectors/*metabolism
    Rhodnius/*metabolism
    Trypanosoma cruzi/*physiology
    Animals ; Chagas Disease/transmission ; Crystallization ; Female ; Heme/metabolism ; Humans ; Insect Vectors/chemistry ; Insect Vectors/parasitology ; Male ; Oviposition ; Oxidation-Reduction ; Rhodnius/chemistry ; Rhodnius/parasitology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Interaction of Mycobacterium leprae with the HaCaT human keratinocyte cell line: new frontiers in the cellular immunology of leprosy.
    Autorzy:
    Lyrio EC; Laboratório de Biopatógenos e Ativação Celular (LaBiopAc), Departamento de Biologia Celular e Molecular, Universidade Federal Fluminense (UFF), Niterói, RJ, Brazil.; Programa de Pós-graduação em Ciências e Biotecnologia, UFF, Niterói, RJ, Brazil.
    Campos-Souza IC; Laboratório de Biopatógenos e Ativação Celular (LaBiopAc), Departamento de Biologia Celular e Molecular, Universidade Federal Fluminense (UFF), Niterói, RJ, Brazil.
    Corrêa LC; Laboratório de Biopatógenos e Ativação Celular (LaBiopAc), Departamento de Biologia Celular e Molecular, Universidade Federal Fluminense (UFF), Niterói, RJ, Brazil.; Programa de Pós-graduação em Ciências e Biotecnologia, UFF, Niterói, RJ, Brazil.
    Lechuga GC; Programa de Pós-graduação em Ciências e Biotecnologia, UFF, Niterói, RJ, Brazil.
    Verícimo M; Programa de Pós-graduação em Patologia, Hospital Universitário, Niterói, RJ, Brazil.
    Castro HC; Programa de Pós-graduação em Ciências e Biotecnologia, UFF, Niterói, RJ, Brazil.; Programa de Pós-graduação em Patologia, Hospital Universitário, Niterói, RJ, Brazil.
    Bourguignon SC; Programa de Pós-graduação em Ciências e Biotecnologia, UFF, Niterói, RJ, Brazil.
    Côrte-Real S; Laboratório de Biologia Estrutural, IOC, FIOCRUZ, RJ, Brazil.
    Ratcliffe N; Programa de Pós-graduação em Ciências e Biotecnologia, UFF, Niterói, RJ, Brazil.; College of Science, Swansea University, Wales, UK.
    Declercq W; Inflammation Research Center, University of Ghent-VIB, Ghent, Belgium.
    Santos DO; Laboratório de Biopatógenos e Ativação Celular (LaBiopAc), Departamento de Biologia Celular e Molecular, Universidade Federal Fluminense (UFF), Niterói, RJ, Brazil.; Programa de Pós-graduação em Ciências e Biotecnologia, UFF, Niterói, RJ, Brazil.
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    Źródło:
    Experimental dermatology [Exp Dermatol] 2015 Jul; Vol. 24 (7), pp. 536-42. Date of Electronic Publication: 2015 May 04.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Keratinocytes/*immunology
    Keratinocytes/*microbiology
    Leprosy/*immunology
    Leprosy/*microbiology
    Mycobacterium leprae/*immunology
    Mycobacterium leprae/*pathogenicity
    Antimicrobial Cationic Peptides/metabolism ; B7-1 Antigen/metabolism ; Cell Adhesion Molecules/metabolism ; Cell Line ; Dendritic Cells/immunology ; Dendritic Cells/microbiology ; Dendritic Cells/pathology ; Humans ; Immunity, Cellular ; Interleukin-1beta/biosynthesis ; Keratinocytes/pathology ; Lectins, C-Type/metabolism ; Leprosy/pathology ; Macrophages/immunology ; Macrophages/microbiology ; Macrophages/pathology ; Phagocytosis ; Receptors, Cell Surface/metabolism ; Tumor Necrosis Factor-alpha/biosynthesis ; Cathelicidins
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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