Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Lederkremer GZ"" wg kryterium: Autor


Tytuł :
Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates.
Autorzy :
García-Huerta P; Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Sector B, Second Floor, Faculty of Medicine, University of Chile, Independencia 1027, P.O. Box 70086, Santiago, Chile.
Troncoso-Escudero P; Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Sector B, Second Floor, Faculty of Medicine, University of Chile, Independencia 1027, P.O. Box 70086, Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, University Mayor, Santiago, Chile.
Wu D; Department of Biomedical Sciences of Cells and Systems, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Thiruvalluvan A; Department of Biomedical Sciences of Cells and Systems, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Cisternas-Olmedo M; Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, University Mayor, Santiago, Chile.
Henríquez DR; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Department of Cell Biology, Faculty of Sciences, University of Chile, Santiago, Chile.
Plate L; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.
Chana-Cuevas P; Faculty of Medical Sciences, University of Santiago de Chile, Santiago, Chile.
Saquel C; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, University Mayor, Santiago, Chile.
Thielen P; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA, 02115, USA.
Longo KA; Proteostasis Therapeutics, Cambridge, MA, USA.
Geddes BJ; Proteostasis Therapeutics, Cambridge, MA, USA.
Lederkremer GZ; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.; George Wise Faculty of Life Sciences, School of Molecular Cell Biology and Biotechnology, Tel Aviv University, Tel Aviv, Israel.
Sharma N; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.; George Wise Faculty of Life Sciences, School of Molecular Cell Biology and Biotechnology, Tel Aviv University, Tel Aviv, Israel.
Shenkman M; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.; George Wise Faculty of Life Sciences, School of Molecular Cell Biology and Biotechnology, Tel Aviv University, Tel Aviv, Israel.
Naphade S; Buck Institute for Research on Aging, Novato, CA, 94945, USA.
Sardi SP; Rare and Neurological Diseases Therapeutic Area, Sanofi, 49 New York Avenue, Framingham, MA, 01701, USA.
Spichiger C; Faculty of Sciences, Institute of Biochemistry and Microbiology, University Austral of Chile, Valdivia, Chile.
Richter HG; Faculty of Medicine, Institute of Anatomy, Histology and Pathology, University Austral of Chile, Valdivia, Chile.
Court FA; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, University Mayor, Santiago, Chile.; Buck Institute for Research on Aging, Novato, CA, 94945, USA.
Tshilenge KT; Buck Institute for Research on Aging, Novato, CA, 94945, USA.
Ellerby LM; Buck Institute for Research on Aging, Novato, CA, 94945, USA.
Wiseman RL; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.
Gonzalez-Billault C; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Department of Cell Biology, Faculty of Sciences, University of Chile, Santiago, Chile.; Buck Institute for Research on Aging, Novato, CA, 94945, USA.
Bergink S; Department of Biomedical Sciences of Cells and Systems, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Vidal RL; Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile. .; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile. .; Center for Integrative Biology, Faculty of Sciences, University Mayor, Santiago, Chile. .
Hetz C; Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile. .; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile. .; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Sector B, Second Floor, Faculty of Medicine, University of Chile, Independencia 1027, P.O. Box 70086, Santiago, Chile. .; Buck Institute for Research on Aging, Novato, CA, 94945, USA. .
Pokaż więcej
Źródło :
Acta neuropathologica [Acta Neuropathol] 2020 Nov; Vol. 140 (5), pp. 737-764. Date of Electronic Publication: 2020 Jul 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Oxidoreductases in Glycoprotein Glycosylation, Folding, and ERAD.
Autorzy :
Patel C; The Shmunis School of Biomedicine and Cancer Research, Cell Biology Division, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 69978, Israel.
Saad H; The Shmunis School of Biomedicine and Cancer Research, Cell Biology Division, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 69978, Israel.
Shenkman M; The Shmunis School of Biomedicine and Cancer Research, Cell Biology Division, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 69978, Israel.
Lederkremer GZ; The Shmunis School of Biomedicine and Cancer Research, Cell Biology Division, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 69978, Israel.
Pokaż więcej
Źródło :
Cells [Cells] 2020 Sep 22; Vol. 9 (9). Date of Electronic Publication: 2020 Sep 22.
Typ publikacji :
Journal Article; Review; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
A novel specific PERK activator reduces toxicity and extends survival in Huntington's disease models.
Autorzy :
Ganz J; Department of Human Molecular Genetics and Biochemistry, Felsenstein Medical Research Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.
Shacham T; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
Kramer M; School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
Shenkman M; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
Eiger H; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
Weinberg N; Department of Human Molecular Genetics and Biochemistry, Felsenstein Medical Research Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.
Iancovici O; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
Roy S; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
Simhaev L; Blavatnik Center for Drug Discovery, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
Da'adoosh B; Blavatnik Center for Drug Discovery, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
Engel H; Blavatnik Center for Drug Discovery, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
Perets N; Department of Human Molecular Genetics and Biochemistry, Felsenstein Medical Research Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.
Barhum Y; Department of Human Molecular Genetics and Biochemistry, Felsenstein Medical Research Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.
Portnoy M; School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
Offen D; Department of Human Molecular Genetics and Biochemistry, Felsenstein Medical Research Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.
Lederkremer GZ; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel. .; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel. .
Pokaż więcej
Źródło :
Scientific reports [Sci Rep] 2020 Apr 23; Vol. 10 (1), pp. 6875. Date of Electronic Publication: 2020 Apr 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Enzyme Activators/*pharmacology
Huntington Disease/*enzymology
eIF-2 Kinase/*metabolism
Animals ; Apoptosis/drug effects ; Disease Models, Animal ; Endoplasmic Reticulum Stress/drug effects ; Enzyme Activators/chemistry ; Eukaryotic Initiation Factor-2/metabolism ; Huntingtin Protein/metabolism ; Huntington Disease/pathology ; Huntington Disease/physiopathology ; Mice ; Models, Biological ; Neostriatum/pathology ; Neurons/drug effects ; Neurons/metabolism ; Neurons/pathology ; Neuroprotective Agents/pharmacology ; Phosphorylation/drug effects ; Signal Transduction/drug effects ; Survival Analysis
Czasopismo naukowe
Tytuł :
Letting go of O -glycans.
Autorzy :
Saad H; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Patel C; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Lederkremer GZ; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel .
Pokaż więcej
Źródło :
The Journal of biological chemistry [J Biol Chem] 2019 Nov 01; Vol. 294 (44), pp. 15912-15913.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Glycoproteins*
Saccharomyces cerevisiae*
Glycosylation ; Mannose ; Oligosaccharides ; Polysaccharides
Czasopismo naukowe
Tytuł :
Compartmentalization and Selective Tagging for Disposal of Misfolded Glycoproteins.
Autorzy :
Shenkman M; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Lederkremer GZ; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel. Electronic address: .
Pokaż więcej
Źródło :
Trends in biochemical sciences [Trends Biochem Sci] 2019 Oct; Vol. 44 (10), pp. 827-836. Date of Electronic Publication: 2019 May 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Glycoproteins/*metabolism
Endoplasmic Reticulum Stress ; Glycoproteins/chemistry ; Humans ; Polysaccharides/chemistry ; Polysaccharides/metabolism ; Protein Folding
Czasopismo naukowe
Tytuł :
Protein Misfolding and ER Stress in Huntington's Disease.
Autorzy :
Shacham T; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.; George Wise Faculty of Life Sciences, School of Molecular Cell Biology and Biotechnology, Tel Aviv University, Tel Aviv, Israel.
Sharma N; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.; George Wise Faculty of Life Sciences, School of Molecular Cell Biology and Biotechnology, Tel Aviv University, Tel Aviv, Israel.
Lederkremer GZ; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.; George Wise Faculty of Life Sciences, School of Molecular Cell Biology and Biotechnology, Tel Aviv University, Tel Aviv, Israel.
Pokaż więcej
Źródło :
Frontiers in molecular biosciences [Front Mol Biosci] 2019 Apr 03; Vol. 6, pp. 20. Date of Electronic Publication: 2019 Apr 03 (Print Publication: 2019).
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Mannosidase activity of EDEM1 and EDEM2 depends on an unfolded state of their glycoprotein substrates.
Autorzy :
Shenkman M; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
Ron E; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
Yehuda R; Avram and Stella Goldstein-Goren Department of Biotechnology Engineering, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel.
Benyair R; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
Khalaila I; Avram and Stella Goldstein-Goren Department of Biotechnology Engineering, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel.
Lederkremer GZ; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel. .
Pokaż więcej
Źródło :
Communications biology [Commun Biol] 2018 Oct 18; Vol. 1, pp. 172. Date of Electronic Publication: 2018 Oct 18 (Print Publication: 2018).
Typ publikacji :
Journal Article
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies