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You search for a phrase ""Lederkremer GZ"" according to the criterion: Author

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    Showing 1-8 from 8 results
    Title:
    PERK Pathway and Neurodegenerative Disease: To Inhibit or to Activate?
    Authors:
    Shacham T; Cell Biology Division, George Wise Faculty of Life Sciences, The Shmunis School of Biomedicine and Cancer Research, Tel Aviv University, Tel Aviv 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 69978, Israel.
    Patel C; Cell Biology Division, George Wise Faculty of Life Sciences, The Shmunis School of Biomedicine and Cancer Research, Tel Aviv University, Tel Aviv 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 69978, Israel.
    Lederkremer GZ; Cell Biology Division, George Wise Faculty of Life Sciences, The Shmunis School of Biomedicine and Cancer Research, Tel Aviv University, Tel Aviv 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 69978, Israel.
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    Source:
    Biomolecules [Biomolecules] 2021 Feb 26; Vol. 11 (3). Date of Electronic Publication: 2021 Feb 26.
    Publication Type:
    Journal Article; Research Support, Non-U.S. Gov't; Review
    MeSH Terms:
    Neurodegenerative Diseases/*metabolism
    eIF-2 Kinase/*metabolism
    Animals ; Endoplasmic Reticulum/metabolism ; Humans ; Signal Transduction/physiology ; Unfolded Protein Response/physiology
    Academic Journal
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    Title:
    Oxidoreductases in Glycoprotein Glycosylation, Folding, and ERAD.
    Authors:
    Patel C; The Shmunis School of Biomedicine and Cancer Research, Cell Biology Division, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 69978, Israel.
    Saad H; The Shmunis School of Biomedicine and Cancer Research, Cell Biology Division, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 69978, Israel.
    Shenkman M; The Shmunis School of Biomedicine and Cancer Research, Cell Biology Division, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 69978, Israel.
    Lederkremer GZ; The Shmunis School of Biomedicine and Cancer Research, Cell Biology Division, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 69978, Israel.
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    Source:
    Cells [Cells] 2020 Sep 22; Vol. 9 (9). Date of Electronic Publication: 2020 Sep 22.
    Publication Type:
    Journal Article; Research Support, Non-U.S. Gov't; Review
    MeSH Terms:
    Protein Processing, Post-Translational*
    Endoplasmic Reticulum-Associated Degradation/*genetics
    Molecular Chaperones/*metabolism
    Oxidoreductases/*metabolism
    Polysaccharides/*metabolism
    Selenoproteins/*metabolism
    Calnexin/genetics ; Calnexin/metabolism ; Disulfides/metabolism ; Endoplasmic Reticulum/enzymology ; Eukaryotic Cells/cytology ; Eukaryotic Cells/enzymology ; Glycosylation ; Humans ; Mannosidases/genetics ; Mannosidases/metabolism ; Molecular Chaperones/genetics ; Oxidation-Reduction ; Oxidoreductases/genetics ; Protein Folding ; Selenoproteins/genetics
    Academic Journal
    Full Text  Link opens in a new window Full TextDetails
    Title:
    A novel specific PERK activator reduces toxicity and extends survival in Huntington's disease models.
    Authors:
    Ganz J; Department of Human Molecular Genetics and Biochemistry, Felsenstein Medical Research Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.
    Shacham T; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
    Kramer M; School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
    Shenkman M; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
    Eiger H; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
    Weinberg N; Department of Human Molecular Genetics and Biochemistry, Felsenstein Medical Research Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.
    Iancovici O; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
    Roy S; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
    Simhaev L; Blavatnik Center for Drug Discovery, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
    Da'adoosh B; Blavatnik Center for Drug Discovery, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
    Engel H; Blavatnik Center for Drug Discovery, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
    Perets N; Department of Human Molecular Genetics and Biochemistry, Felsenstein Medical Research Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.
    Barhum Y; Department of Human Molecular Genetics and Biochemistry, Felsenstein Medical Research Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.
    Portnoy M; School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
    Offen D; Department of Human Molecular Genetics and Biochemistry, Felsenstein Medical Research Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel.
    Lederkremer GZ; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel. .; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel. .
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    Source:
    Scientific reports [Sci Rep] 2020 Apr 23; Vol. 10 (1), pp. 6875. Date of Electronic Publication: 2020 Apr 23.
    Publication Type:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Enzyme Activators/*pharmacology
    Huntington Disease/*enzymology
    eIF-2 Kinase/*metabolism
    Animals ; Apoptosis/drug effects ; Disease Models, Animal ; Endoplasmic Reticulum Stress/drug effects ; Enzyme Activators/chemistry ; Eukaryotic Initiation Factor-2/metabolism ; Huntingtin Protein/metabolism ; Huntington Disease/pathology ; Huntington Disease/physiopathology ; Mice ; Models, Biological ; Neostriatum/pathology ; Neurons/drug effects ; Neurons/metabolism ; Neurons/pathology ; Neuroprotective Agents/pharmacology ; Phosphorylation/drug effects ; Signal Transduction/drug effects ; Survival Analysis
    Academic Journal
    Full Text  Link opens in a new window Full TextDetails
    Title:
    Mannosidase activity of EDEM1 and EDEM2 depends on an unfolded state of their glycoprotein substrates.
    Authors:
    Shenkman M; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
    Ron E; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
    Yehuda R; Avram and Stella Goldstein-Goren Department of Biotechnology Engineering, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel.
    Benyair R; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
    Khalaila I; Avram and Stella Goldstein-Goren Department of Biotechnology Engineering, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel.
    Lederkremer GZ; School of Molecular Cell Biology and Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel. .
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    Source:
    Communications biology [Commun Biol] 2018 Oct 18; Vol. 1, pp. 172. Date of Electronic Publication: 2018 Oct 18 (Print Publication: 2018).
    Publication Type:
    Journal Article
    Academic Journal
    Full Text  Link opens in a new window Full TextDetails
    Title:
    ER stress-induced eIF2-alpha phosphorylation underlies sensitivity of striatal neurons to pathogenic huntingtin.
    Authors:
    Leitman J; Department of Cell Research and Immunology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.
    Barak B; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel; Department of Neurobiology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.
    Benyair R; Department of Cell Research and Immunology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.
    Shenkman M; Department of Cell Research and Immunology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.
    Ashery U; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel; Department of Neurobiology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.
    Hartl FU; Department of Cellular Biochemistry, Max Planck Institute of Biochemistry, Martinsried, Germany.
    Lederkremer GZ; Department of Cell Research and Immunology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.
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    Source:
    PloS one [PLoS One] 2014 Mar 03; Vol. 9 (3), pp. e90803. Date of Electronic Publication: 2014 Mar 03 (Print Publication: 2014).
    Publication Type:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Endoplasmic Reticulum Stress/*physiology
    Eukaryotic Initiation Factor-2/*metabolism
    Nerve Tissue Proteins/*metabolism
    Neurons/*metabolism
    Nuclear Proteins/*metabolism
    Visual Cortex/*cytology
    Animals ; DNA Primers/genetics ; Flow Cytometry ; Fluorescent Antibody Technique ; Genetic Vectors/genetics ; HEK293 Cells ; Humans ; Huntingtin Protein ; Immunoblotting ; Mice ; NIH 3T3 Cells ; Phosphorylation ; Protein Serine-Threonine Kinases/metabolism ; Reverse Transcriptase Polymerase Chain Reaction
    Academic Journal
    Full Text  Link opens in a new windowDetails
    Title:
    A secreted form of the asialoglycoprotein receptor, sH2a, as a novel potential noninvasive marker for liver fibrosis.
    Authors:
    Veselkin E; Department of Cell Research and Immunology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.
    Kondratyev M
    Lurie Y
    Ron E
    Santo M
    Reif S
    Elashvili I
    Bar L
    Lederkremer GZ
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    Source:
    PloS one [PLoS One] 2011; Vol. 6 (11), pp. e27210. Date of Electronic Publication: 2011 Nov 11.
    Publication Type:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Asialoglycoprotein Receptor/*blood
    Asialoglycoprotein Receptor/*metabolism
    Liver Cirrhosis/*metabolism
    Adult ; Alanine Transaminase/blood ; Alanine Transaminase/metabolism ; Aspartate Aminotransferases/blood ; Aspartate Aminotransferases/metabolism ; Bilirubin/blood ; Bilirubin/metabolism ; Biomarkers/blood ; Confidence Intervals ; Female ; Hepatitis C/blood ; Hepatitis C/metabolism ; Humans ; In Vitro Techniques ; Liver Cirrhosis/blood ; Male ; Middle Aged ; Reverse Transcriptase Polymerase Chain Reaction ; Young Adult
    Academic Journal
    Full Text  Link opens in a new windowDetails
      Showing 1-8 from 8 results

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