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Wyszukujesz frazę ""Lee, Yu-May"" wg kryterium: Autor


Wyświetlanie 1-17 z 17
Tytuł :
Glypican-3 induces oncogenicity by preventing IGF-1R degradation, a process that can be blocked by Grb10.
Autorzy :
Cheng W; Department of Pathology, Kee-Lung Hospital, Ministry of Health and Welfare, Kee-Lung, Taiwan.; Ching Kuo Institute of Management and Health, Kee-Lung, Taiwan.; National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.
Huang PC; Institute of Biochemical Sciences, National Taiwan University, Taipei, Taiwan.; Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
Chao HM; Department of Pathology, Wang Fang Hospital, Taipei Medical University, Taipei, Taiwan.
Jeng YM; Graduate Institute of Pathology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Hsu HC; Graduate Institute of Pathology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Pan HW; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Hwu WL; Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan.
Lee YM; Institute of Biochemical Sciences, National Taiwan University, Taipei, Taiwan.; Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.; Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan.
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Źródło :
Oncotarget [Oncotarget] 2017 Jul 06; Vol. 8 (46), pp. 80429-80442. Date of Electronic Publication: 2017 Jul 06 (Print Publication: 2017).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Gene therapy with modified U1 small nuclear RNA.
Autorzy :
Hwu WL; a Department of Pediatrics and Medical Genetics , National Taiwan University Hospital and National Taiwan University College of Medicine , Taipei , Taiwan.
Lee YM; a Department of Pediatrics and Medical Genetics , National Taiwan University Hospital and National Taiwan University College of Medicine , Taipei , Taiwan.
Lee NC; a Department of Pediatrics and Medical Genetics , National Taiwan University Hospital and National Taiwan University College of Medicine , Taipei , Taiwan.
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Źródło :
Expert review of endocrinology & metabolism [Expert Rev Endocrinol Metab] 2017 May; Vol. 12 (3), pp. 171-175. Date of Electronic Publication: 2017 Apr 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Mutation-adapted U1 snRNA corrects a splicing error of the dopa decarboxylase gene.
Autorzy :
Lee NC; Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan.; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Lee YM; Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan.
Chen PW; Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan.
Byrne BJ; Powell Gene Therapy Center, University of Florida, Gainesville, FL, USA.
Hwu WL; Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan.; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
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Źródło :
Human molecular genetics [Hum Mol Genet] 2016 Dec 01; Vol. 25 (23), pp. 5142-5147.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Therapy*
Amino Acid Metabolism, Inborn Errors/*genetics
Aromatic-L-Amino-Acid Decarboxylases/*deficiency
Dopa Decarboxylase/*genetics
RNA, Small Nuclear/*genetics
Amino Acid Metabolism, Inborn Errors/therapy ; Animals ; Aromatic-L-Amino-Acid Decarboxylases/genetics ; Dependovirus/genetics ; Disease Models, Animal ; Exons/genetics ; Gene Knock-In Techniques ; Humans ; Introns/genetics ; Mice ; Mutation ; Neurotransmitter Agents/genetics ; RNA Splicing/genetics ; RNA, Small Nuclear/administration & dosage
SCR Disease Name :
Aromatic amino acid decarboxylase deficiency
Czasopismo naukowe
Tytuł :
The Novel VEGF121-VEGF165 Fusion Attenuates Angiogenesis and Drug Resistance via Targeting VEGFR2-HIF-1α-VEGF165/Lon Signaling Through PI3K-AKT-mTOR Pathway.
Autorzy :
Tsai JL
Lee YM
Pan CY
Lee AY; National Institute of Cancer Research, National Health Research Institutes, 35 Keyan Rd., Zhunan, Miaoli 35053, Taiwan. .
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Źródło :
Current cancer drug targets [Curr Cancer Drug Targets] 2016; Vol. 16 (3), pp. 275-86.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Colonic Neoplasms/*drug therapy
Drug Resistance, Neoplasm/*genetics
Hypoxia-Inducible Factor 1, alpha Subunit/*antagonists & inhibitors
Neovascularization, Pathologic/*prevention & control
Recombinant Fusion Proteins/*pharmacology
Signal Transduction/*drug effects
Vascular Endothelial Growth Factor Receptor-2/*antagonists & inhibitors
Blotting, Western ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Colonic Neoplasms/metabolism ; Colonic Neoplasms/pathology ; Endothelium, Vascular/cytology ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/metabolism ; Human Umbilical Vein Endothelial Cells/cytology ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; TOR Serine-Threonine Kinases/metabolism ; Vascular Endothelial Growth Factor A/antagonists & inhibitors ; Vascular Endothelial Growth Factor A/genetics
Czasopismo naukowe
Tytuł :
Exchange of active site residues alters substrate specificity in extremely thermostable β-glycosidase from Thermococcus kodakarensis KOD1.
Autorzy :
Hwa KY; Department of Molecular Science and Engineering, National Taipei University of Technology, Taipei, Taiwan, ROC; Center for Biomedical Industry, National Taipei University of Technology, Taipei, Taiwan, ROC. Electronic address: .
Subramani B; Department of Molecular Science and Engineering, National Taipei University of Technology, Taipei, Taiwan, ROC.
Shen ST; Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan, ROC.
Lee YM; Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan, ROC.
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Źródło :
Enzyme and microbial technology [Enzyme Microb Technol] 2015 Sep; Vol. 77, pp. 14-20. Date of Electronic Publication: 2015 May 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Archaeal Proteins/*chemistry
Archaeal Proteins/*metabolism
Glycoside Hydrolases/*chemistry
Glycoside Hydrolases/*metabolism
Thermococcus/*enzymology
Amino Acid Sequence ; Amino Acid Substitution ; Archaeal Proteins/genetics ; Catalytic Domain/genetics ; Enzyme Activation ; Enzyme Stability ; Glycoside Hydrolases/genetics ; Hot Temperature ; Kinetics ; Molecular Sequence Data ; Mutagenesis, Site-Directed ; Protein Conformation ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Sequence Homology, Amino Acid ; Substrate Specificity ; Thermococcus/genetics ; Thermodynamics ; alpha-L-Fucosidase/chemistry ; alpha-L-Fucosidase/genetics ; alpha-L-Fucosidase/metabolism ; beta-Galactosidase/chemistry ; beta-Galactosidase/genetics ; beta-Galactosidase/metabolism ; beta-Glucosidase/chemistry ; beta-Glucosidase/genetics ; beta-Glucosidase/metabolism ; beta-Mannosidase/chemistry ; beta-Mannosidase/genetics ; beta-Mannosidase/metabolism
Czasopismo naukowe
Tytuł :
An intermolecular disulfide bond is required for thermostability and thermoactivity of β-glycosidase from Thermococcus kodakarensis KOD1.
Autorzy :
Hwa KY; Department of Molecular Science and Engineering, National Taipei University of Technology, Taipei, Taiwan, .
Subramani B
Shen ST
Lee YM
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Źródło :
Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2014 Sep; Vol. 98 (18), pp. 7825-36. Date of Electronic Publication: 2014 Apr 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disulfides/*chemistry
Glycoside Hydrolases/*chemistry
Glycoside Hydrolases/*metabolism
Thermococcus/*enzymology
Enzyme Stability ; Mutagenesis, Site-Directed ; Temperature
Czasopismo naukowe
Tytuł :
Inhibition of glutaminyl cyclase attenuates cell migration modulated by monocyte chemoattractant proteins.
Autorzy :
Chen YL; Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
Huang KF
Kuo WC
Lo YC
Lee YM
Wang AH
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Źródło :
The Biochemical journal [Biochem J] 2012 Mar 01; Vol. 442 (2), pp. 403-12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aminoacyltransferases/*antagonists & inhibitors
Cell Movement/*physiology
Monocyte Chemoattractant Proteins/*physiology
Aminoacyltransferases/chemistry ; Aminoacyltransferases/genetics ; Aminoacyltransferases/physiology ; Base Sequence ; Cell Movement/drug effects ; Enzyme Inhibitors/pharmacology ; Gene Knockdown Techniques ; Humans ; Inflammation/physiopathology ; Lipopolysaccharides/pharmacology ; Models, Molecular ; Monocyte Chemoattractant Proteins/chemistry ; Monocytes/drug effects ; Monocytes/physiology ; Protein Interaction Domains and Motifs ; RNA, Small Interfering/genetics ; U937 Cells
Czasopismo naukowe
Tytuł :
White spot syndrome virus protein ICP11: A histone-binding DNA mimic that disrupts nucleosome assembly.
Autorzy :
Wang HC; Institute of Biochemical Sciences, National Taiwan University, Taipei 106, Taiwan.
Wang HC
Ko TP
Lee YM
Leu JH
Ho CH
Huang WP
Lo CF
Wang AH
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2008 Dec 30; Vol. 105 (52), pp. 20758-63. Date of Electronic Publication: 2008 Dec 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Viral Proteins/*chemistry
White spot syndrome virus 1/*chemistry
Animals ; Crystallography, X-Ray ; DNA/chemistry ; DNA/metabolism ; Dimerization ; Hemocytes/virology ; Histones/chemistry ; Histones/metabolism ; Nucleosomes/chemistry ; Nucleosomes/metabolism ; Penaeidae/virology ; Protein Binding/physiology ; Protein Structure, Quaternary/physiology ; Viral Proteins/metabolism ; White spot syndrome virus 1/metabolism
Czasopismo naukowe
Tytuł :
Glypican-3-mediated oncogenesis involves the Insulin-like growth factor-signaling pathway.
Autorzy :
Cheng W; Graduate Institute of Pathology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Tseng CJ
Lin TT
Cheng I
Pan HW
Hsu HC
Lee YM
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Źródło :
Carcinogenesis [Carcinogenesis] 2008 Jul; Vol. 29 (7), pp. 1319-26. Date of Electronic Publication: 2008 Apr 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Hepatocellular/*metabolism
Glypicans/*genetics
Glypicans/*metabolism
Insulin-Like Growth Factor II/*metabolism
Liver Neoplasms/*metabolism
Receptor, IGF Type 1/*metabolism
Animals ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/metabolism ; Cell Transformation, Neoplastic/pathology ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Glypicans/biosynthesis ; HeLa Cells ; Humans ; Liver Neoplasms/genetics ; Liver Neoplasms/pathology ; Mice ; NIH 3T3 Cells ; Phosphorylation ; Signal Transduction ; Transfection
Czasopismo naukowe
Tytuł :
Hsp27 decreases inclusion body formation from mutated GTP-cyclohydrolase I protein.
Autorzy :
Chiou YW; Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
Hwu WL
Lee YM
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2008 Mar; Vol. 1782 (3), pp. 169-79. Date of Electronic Publication: 2008 Jan 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
GTP Cyclohydrolase/*physiology
Heat-Shock Proteins/*pharmacology
Inclusion Bodies/*drug effects
Neoplasm Proteins/*pharmacology
Animals ; Cells, Cultured ; Cricetinae ; Fluorescent Antibody Technique ; GTP Cyclohydrolase/genetics ; HSP27 Heat-Shock Proteins ; Molecular Chaperones ; Mutation ; Okadaic Acid/pharmacology ; Phosphorylation ; Transfection
Czasopismo naukowe
Tytuł :
Increased oxidative damage and mitochondrial abnormalities in the peripheral blood of Huntington's disease patients.
Autorzy :
Chen CM; Department of Neurology, Chang Gung Memorial Hospital, Chang-Gung University College of Medicine, Taipei, Taiwan. />Wu YR
Cheng ML
Liu JL
Lee YM
Lee PW
Soong BW
Chiu DT
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2007 Jul 27; Vol. 359 (2), pp. 335-40. Date of Electronic Publication: 2007 May 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Oxidative Stress*
Huntington Disease/*blood
Mitochondria/*metabolism
8-Hydroxy-2'-Deoxyguanosine ; Adult ; Aged ; Biomarkers/metabolism ; DNA, Mitochondrial/metabolism ; Deoxyguanosine/analogs & derivatives ; Deoxyguanosine/pharmacology ; Erythrocytes/metabolism ; Female ; Humans ; Male ; Malondialdehyde/blood ; Middle Aged ; Superoxide Dismutase/blood
Czasopismo naukowe
Tytuł :
Differential expression of mu-opioid receptor gene in CXBK and B6 mice by Sp1.
Autorzy :
Lee PW; Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
Wu S
Lee YM
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Źródło :
Molecular pharmacology [Mol Pharmacol] 2004 Dec; Vol. 66 (6), pp. 1580-4.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Receptors, Opioid, mu/*genetics
Sp1 Transcription Factor/*metabolism
5' Untranslated Regions/genetics ; Animals ; Base Sequence ; Cell Line ; Cell Line, Tumor ; Gene Expression Regulation ; Genes, Reporter ; Mice ; Mice, Inbred Strains ; Mice, Mutant Strains ; PC12 Cells ; Promoter Regions, Genetic ; Rats ; Receptors, Opioid, mu/deficiency ; Species Specificity ; Transfection
Czasopismo naukowe
Tytuł :
RNF4 is a coactivator for nuclear factor Y on GTP cyclohydrolase I proximal promoter.
Autorzy :
Wu SM; Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan, Republic of China.
Kuo WC
Hwu WL
Hwa KY
Mantovani R
Lee YM
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Źródło :
Molecular pharmacology [Mol Pharmacol] 2004 Nov; Vol. 66 (5), pp. 1317-24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Promoter Regions, Genetic*
CCAAT-Binding Factor/*physiology
GTP Cyclohydrolase/*genetics
Nuclear Proteins/*physiology
Transcription Factors/*physiology
Base Sequence ; CCAAT-Binding Factor/metabolism ; CCAAT-Enhancer-Binding Proteins/physiology ; Cells, Cultured ; GTP Cyclohydrolase/metabolism ; Gene Expression/physiology ; Humans ; Immunoprecipitation ; Molecular Sequence Data ; Protein Structure, Tertiary ; Transcription Factors/metabolism ; Transcriptional Activation
Czasopismo naukowe
Tytuł :
Molecular chaperones affect GTP cyclohydrolase I mutations in dopa-responsive dystonia.
Autorzy :
Hwu WL; Department of Pediatrics and Medical Genetics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taiwan.
Lu MY
Hwa KY
Fan SW
Lee YM
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Źródło :
Annals of neurology [Ann Neurol] 2004 Jun; Vol. 55 (6), pp. 875-8.
Typ publikacji :
Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Mutation*
Dystonia/*metabolism
GTP Cyclohydrolase/*genetics
Molecular Chaperones/*physiology
Animals ; Animals, Newborn ; Benzoquinones ; Blotting, Northern/methods ; Blotting, Western/methods ; Cell Line ; Cricetinae ; DNA Mutational Analysis ; Dystonia/chemically induced ; Dystonia/genetics ; Embryo, Mammalian ; Enzyme Inhibitors/pharmacology ; GTP Cyclohydrolase/metabolism ; Gene Expression Regulation/drug effects ; Glutamic Acid/genetics ; Glycine/genetics ; HSP40 Heat-Shock Proteins ; HSP70 Heat-Shock Proteins/metabolism ; HSP90 Heat-Shock Proteins/metabolism ; Heat-Shock Proteins/metabolism ; Humans ; Lactams, Macrocyclic ; Levodopa ; Proteins/metabolism ; Quinones/pharmacology ; RNA, Messenger/biosynthesis ; Reverse Transcriptase Polymerase Chain Reaction/methods ; Time Factors ; Transfection/methods
Czasopismo naukowe
Tytuł :
Differential activation of a C/EBP beta isoform by a novel redox switch may confer the lipopolysaccharide-inducible expression of interleukin-6 gene.
Autorzy :
Su WC; Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei.
Chou HY
Chang CJ
Lee YM
Chen WH
Huang KH
Lee MY
Lee SC
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2003 Dec 19; Vol. 278 (51), pp. 51150-8. Date of Electronic Publication: 2003 Oct 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CCAAT-Enhancer-Binding Protein-beta/*metabolism
Gene Expression Regulation/*drug effects
Interleukin-6/*biosynthesis
Lipopolysaccharides/*pharmacology
CCAAT-Enhancer-Binding Protein-beta/chemistry ; CCAAT-Enhancer-Binding Protein-beta/physiology ; Cell Line ; Cysteine ; Disulfides ; Humans ; Interleukin-6/genetics ; Oxidation-Reduction/drug effects ; Protein Isoforms/physiology ; Protein Structure, Tertiary
Czasopismo naukowe
Tytuł :
Transcriptional regulation of mu opioid receptor gene by cAMP pathway.
Autorzy :
Lee PW; Institute of Biological Chemistry, Academia Sinica, 128 Section 2, Academy Road, Nankang, Taipei 115, Taiwan. />Lee YM
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Źródło :
Molecular pharmacology [Mol Pharmacol] 2003 Dec; Vol. 64 (6), pp. 1410-8.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cyclic AMP/*physiology
Receptors, Opioid, mu/*biosynthesis
Receptors, Opioid, mu/*genetics
Regulatory Sequences, Nucleic Acid/*physiology
Signal Transduction/*genetics
Transcription, Genetic/*physiology
Animals ; Base Sequence ; Cell Line ; Fentanyl/pharmacology ; Humans ; Mice ; Molecular Sequence Data ; Rats ; Regulatory Sequences, Nucleic Acid/drug effects ; Signal Transduction/drug effects ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
Regulation of GTP cyclohydrolase I by alternative splicing in mononuclear cells.
Autorzy :
Hwu WL; Department of Pediatrics and Medical Genetics, National Taiwan University Hospital and National Taiwan University, College of Medicine, Taipei, Taiwan ROC.
Yeh HY
Fang SW
Chiang HS
Chiou YW
Lee YM
Pokaż więcej
Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2003 Jul 11; Vol. 306 (4), pp. 937-42.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Enzymologic*
GTP Cyclohydrolase/*biosynthesis
Leukocytes, Mononuclear/*enzymology
Alternative Splicing ; Blotting, Western ; Cell Line ; DNA, Complementary/metabolism ; Dose-Response Relationship, Drug ; GTP Cyclohydrolase/chemistry ; GTP Cyclohydrolase/genetics ; Genes, Dominant ; Humans ; Nitric Oxide Synthase/metabolism ; Nitric Oxide Synthase Type II ; Plasmids/metabolism ; Polymerase Chain Reaction ; RNA, Messenger/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Time Factors ; Transcription, Genetic ; Transfection ; Tumor Cells, Cultured
Czasopismo naukowe
    Wyświetlanie 1-17 z 17

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