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Tytuł:
Inhibition of CNOT2 Induces Apoptosis via MID1IP1 in Colorectal Cancer Cells by Activating p53.
Autorzy:
Jung JH; College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Lee D; Soonchunhyang Institute of Medi-bio Science (SIMS), Soonchunhyang University, Cheonan-si 31151, Korea.
Ko HM; College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Jang HJ; College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
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Źródło:
Biomolecules [Biomolecules] 2021 Oct 10; Vol. 11 (10). Date of Electronic Publication: 2021 Oct 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*/drug effects
Colorectal Neoplasms/*metabolism
Colorectal Neoplasms/*pathology
Cytoskeletal Proteins/*metabolism
Repressor Proteins/*antagonists & inhibitors
Tumor Suppressor Protein p53/*metabolism
Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; DNA Damage ; Doxorubicin/pharmacology ; Gene Knockdown Techniques ; Humans ; Models, Biological ; Protein Stability ; Repressor Proteins/metabolism
Czasopismo naukowe
Tytuł:
Krill Oil Attenuates Cognitive Impairment by the Regulation of Oxidative Stress and Neuronal Apoptosis in an Amyloid β-Induced Alzheimer's Disease Mouse Model.
Autorzy:
Kim JH; Department of Food Science and Nutrition, Pusan National University, Busan 46241, Korea.
Meng HW; Department of Food Science and Nutrition, Pusan National University, Busan 46241, Korea.
He MT; Department of Food Science and Nutrition, Pusan National University, Busan 46241, Korea.
Choi JM; Department of Food Science and Nutrition, Pusan National University, Busan 46241, Korea.; Department of Food and Nutrition, Kyungsung University, Busan 48434, Korea.
Lee D; NZ Origin Ltd., Busan 48059, Korea.
Cho EJ; Department of Food Science and Nutrition, Pusan National University, Busan 46241, Korea.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2020 Aug 28; Vol. 25 (17). Date of Electronic Publication: 2020 Aug 28.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease/*metabolism
Apoptosis/*drug effects
Euphausiacea/*chemistry
Fatty Acids, Unsaturated/*pharmacology
Neurons/*drug effects
Neurons/*metabolism
Oxidative Stress/*drug effects
Alzheimer Disease/drug therapy ; Alzheimer Disease/etiology ; Alzheimer Disease/psychology ; Amyloid beta-Peptides/adverse effects ; Animals ; Behavior, Animal ; Biomarkers ; Cognition/drug effects ; Cognitive Dysfunction/drug therapy ; Cognitive Dysfunction/etiology ; Cognitive Dysfunction/metabolism ; Disease Models, Animal ; Fatty Acids, Unsaturated/chemistry ; Maze Learning/drug effects ; Memory/drug effects ; Mice ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Anti-Apoptotic and Antioxidant Effects of 3- Epi- Iso -Seco -Tanapartholide Isolated from Artemisia Argyi Against Iodixanol-Induced Kidney Epithelial Cell Death.
Autorzy:
Lee D; College of Korean Medicine, Gachon University, Seongnam 13120, Korea.
Kim KO; Department of Biosystems and Biotechnology, College of Life Science and Biotechnology, Korea University, Seoul 02841, Korea.
Lee D; Department of Biosystems and Biotechnology, College of Life Science and Biotechnology, Korea University, Seoul 02841, Korea.
Kang KS; College of Korean Medicine, Gachon University, Seongnam 13120, Korea.
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Źródło:
Biomolecules [Biomolecules] 2020 Jun 05; Vol. 10 (6). Date of Electronic Publication: 2020 Jun 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antioxidants/*pharmacology
Apoptosis/*drug effects
Artemisia/*chemistry
Epithelial Cells/*drug effects
Kidney Tubules, Proximal/*drug effects
Triiodobenzoic Acids/*antagonists & inhibitors
Animals ; Antioxidants/chemistry ; Antioxidants/isolation & purification ; Cell Death/drug effects ; Cells, Cultured ; Epithelial Cells/metabolism ; Kidney Tubules, Proximal/metabolism ; Molecular Structure ; Oxidative Stress/drug effects ; Swine ; Triiodobenzoic Acids/pharmacology
Czasopismo naukowe
Tytuł:
Aviculin Isolated from Lespedeza cuneata Induce Apoptosis in Breast Cancer Cells through Mitochondria-Mediated Caspase Activation Pathway.
Autorzy:
Lee D; College of Korean Medicine, Gachon University, Seongnam 13120, Korea.
Lee YH; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Lee KH; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Lee BS; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Alishir A; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Ko YJ; Laboratory of Nuclear Magnetic Resonance, National Center for Inter-University Research Facilities (NCIRF), Seoul National University, Gwanak-gu, Seoul 08826, Korea.
Kang KS; College of Korean Medicine, Gachon University, Seongnam 13120, Korea.
Kim KH; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2020 Apr 08; Vol. 25 (7). Date of Electronic Publication: 2020 Apr 08.
Typ publikacji:
Journal Article
MeSH Terms:
Signal Transduction*/drug effects
Apoptosis/*drug effects
Breast Neoplasms/*pathology
Caspases/*metabolism
Glycosides/*isolation & purification
Glycosides/*pharmacology
Lespedeza/*chemistry
Mitochondria/*metabolism
Breast Neoplasms/metabolism ; Cell Nucleus Shape/drug effects ; Cisplatin/pharmacology ; Enzyme Activation/drug effects ; Female ; Glycosides/chemistry ; Humans ; MCF-7 Cells ; Methanol/chemistry ; Mitochondria/drug effects ; Plant Extracts/pharmacology
Czasopismo naukowe
Tytuł:
Farnesiferol C Induces Apoptosis in Chronic Myelogenous Leukemia Cells as an Imatinib Sensitizer via Caspase Activation and HDAC (Histone Deacetylase) Inactivation.
Autorzy:
Jung JH; College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Park JE; College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Sim DY; College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Im E; College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Park WY; College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Lee D; College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Shim BS; College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Kim SH; College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 Nov 06; Vol. 20 (22). Date of Electronic Publication: 2019 Nov 06.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Caspases/*metabolism
Coumarins/*pharmacology
Histone Deacetylase Inhibitors/*pharmacology
Histone Deacetylases/*metabolism
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*enzymology
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*pathology
Acetylation ; Cell Cycle Checkpoints/drug effects ; Cell Cycle Proteins/metabolism ; Coumarins/chemistry ; Enzyme Activation/drug effects ; Histone Deacetylases/genetics ; Histones/metabolism ; Humans ; K562 Cells ; Models, Biological ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł:
Betulinic Acid Suppresses Ovarian Cancer Cell Proliferation through Induction of Apoptosis.
Autorzy:
Lee D; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Lee SR; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Kang KS; College of Korean Medicine, Gachon University, Seongnam 13120, Korea.
Ko Y; Department of Obstetrics and Gynecology, University of Ulsan, Asan Medical Center, Seoul 05505, Korea.
Pang C; School of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Korea.
Yamabe N; College of Korean Medicine, Gachon University, Seongnam 13120, Korea. .
Kim KH; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. .
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Źródło:
Biomolecules [Biomolecules] 2019 Jul 03; Vol. 9 (7). Date of Electronic Publication: 2019 Jul 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents, Phytogenic/*pharmacology
Apoptosis/*drug effects
Cornaceae/*chemistry
Plant Extracts/*pharmacology
Triterpenes/*pharmacology
Antineoplastic Agents, Phytogenic/chemistry ; Antineoplastic Agents, Phytogenic/isolation & purification ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Female ; Humans ; Molecular Conformation ; Pentacyclic Triterpenes ; Plant Bark/chemistry ; Plant Extracts/chemistry ; Plant Extracts/isolation & purification ; Plant Stems/chemistry ; Structure-Activity Relationship ; Triterpenes/chemistry ; Triterpenes/isolation & purification ; Tumor Cells, Cultured ; Betulinic Acid
Czasopismo naukowe
Tytuł:
Protective Effect of Phenolic Compounds Isolated from Mugwort ( Artemisia argyi ) against Contrast-Induced Apoptosis in Kidney Epithelium Cell Line LLC-PK1.
Autorzy:
Kim KO; Department of Biosystems and Biotechnology, College of Life Science and Biotechnology, Korea University, Seoul 02841, Korea. .
Lee D; School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Korea. .
Hiep NT; Department of Biosystems and Biotechnology, College of Life Science and Biotechnology, Korea University, Seoul 02841, Korea. .
Song JH; College of Korean Medicine, Gachon University, Seongnam 13120, Korea. .
Lee HJ; Department of Food and Nutrition, College of Bio-Nano technology, Gachon University, Seongnam 13120, Korea. .
Lee D; Department of Biosystems and Biotechnology, College of Life Science and Biotechnology, Korea University, Seoul 02841, Korea. .
Kang KS; College of Korean Medicine, Gachon University, Seongnam 13120, Korea. .
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2019 Jan 07; Vol. 24 (1). Date of Electronic Publication: 2019 Jan 07.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Contrast Media/*adverse effects
Kidney/*drug effects
Phenols/*pharmacology
Animals ; Artemisia ; Cell Survival/drug effects ; Gene Expression Regulation/drug effects ; Hepatitis A Virus Cellular Receptor 1/genetics ; Humans ; JNK Mitogen-Activated Protein Kinases/genetics ; Kidney/injuries ; Kidney/pathology ; LLC-PK1 Cells ; Reactive Oxygen Species/metabolism ; Swine ; Triiodobenzoic Acids/adverse effects ; p38 Mitogen-Activated Protein Kinases/genetics
Czasopismo naukowe
Tytuł:
Identification of bioactive heterocyclic compounds from mulberry and their protective effect against streptozotocin-induced apoptosis in INS-1 cells.
Autorzy:
Song JH; Department of Medicine, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea.
Lee D; College of Korean Medicine, Gacheon University, Seongnam, Gyeonggi 13120, Republic of Korea.
Lee SR; School of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi 16419, Republic of Korea.
Yu JS; School of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi 16419, Republic of Korea.
Jang TS; Institute of Green Bio Science and Technology, Seoul National University, Pyeongchang, Gangwon 25354, Republic of Korea.
Nam JW; College of Pharmacy, Yeungnam University, Gyeongsan, Gyeongbuk 38541, Republic of Korea.
Kim KH; School of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi 16419, Republic of Korea.
Kang KS; College of Korean Medicine, Gacheon University, Seongnam, Gyeonggi 13120, Republic of Korea.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2018 Apr; Vol. 17 (4), pp. 5982-5987. Date of Electronic Publication: 2018 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Heterocyclic Compounds/*pharmacology
Morus/*chemistry
Plant Extracts/*pharmacology
Protective Agents/*pharmacology
Streptozocin/*pharmacology
Animals ; Cell Line ; Heterocyclic Compounds/chemistry ; Insulin-Secreting Cells/drug effects ; Insulin-Secreting Cells/metabolism ; Plant Extracts/chemistry ; Protective Agents/chemistry ; Rats ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Inhibition of Intracellular ROS Accumulation by Formononetin Attenuates Cisplatin-Mediated Apoptosis in LLC-PK1 Cells.
Autorzy:
Lee H; Department of Korean International Medicine, College of Korean Medicine, Gachon University, Seongnam 13120, Korea. .
Lee D; College of Korean Medicine, Gachon University, Seongnam 13120, Korea. .
Kang KS; College of Korean Medicine, Gachon University, Seongnam 13120, Korea. .
Song JH; Department of Medicine, University of Ulsan College of Medicine, Seoul 05505, Korea. .
Choi YK; Department of Korean International Medicine, College of Korean Medicine, Gachon University, Seongnam 13120, Korea. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2018 Mar 12; Vol. 19 (3). Date of Electronic Publication: 2018 Mar 12.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants/*pharmacology
Apoptosis/*drug effects
Isoflavones/*pharmacology
Reactive Oxygen Species/*metabolism
Animals ; Antineoplastic Agents/pharmacology ; Cell Line ; Chromatin/metabolism ; Cisplatin/pharmacology ; HeLa Cells ; Humans ; JNK Mitogen-Activated Protein Kinases/metabolism ; Swine
Czasopismo naukowe
Tytuł:
Stress-induced nuclear translocation of CDK5 suppresses neuronal death by downregulating ERK activation via VRK3 phosphorylation.
Autorzy:
Song H; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, 37673, Republic of Korea.
Kim W; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, 37673, Republic of Korea.
Choi JH; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, 37673, Republic of Korea.
Kim SH; Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang, Gyeongbuk, 37673, Republic of Korea.
Lee D; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, 37673, Republic of Korea.
Park CH; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, 37673, Republic of Korea.
Kim S; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, 37673, Republic of Korea.
Kim DY; Department of Pharmacology, School of Dentistry, Brain Science and Engineering Institute, Kyungpook National University, Daegu, Gyeongbuk, 41940, Republic of Korea.
Kim KT; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, 37673, Republic of Korea.; Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang, Gyeongbuk, 37673, Republic of Korea.
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Źródło:
Scientific reports [Sci Rep] 2016 Jun 27; Vol. 6, pp. 28634. Date of Electronic Publication: 2016 Jun 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
MAP Kinase Signaling System*
Oxidative Stress*
Cell Nucleus/*metabolism
Cyclin-Dependent Kinase 5/*metabolism
Neurons/*metabolism
Protein Serine-Threonine Kinases/*metabolism
Active Transport, Cell Nucleus/drug effects ; Active Transport, Cell Nucleus/genetics ; Animals ; Cell Line, Tumor ; Cell Nucleus/genetics ; Cyclin-Dependent Kinase 5/genetics ; Humans ; Hydrogen Peroxide/pharmacology ; Mice ; Mice, Knockout ; Neurons/pathology ; Phosphorylation/drug effects ; Phosphorylation/genetics ; Protein Serine-Threonine Kinases/genetics
Czasopismo naukowe
Tytuł:
Bone marrow analysis of immune cells and apoptosis in patients with systemic lupus erythematosus.
Autorzy:
Park JW; Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Moon SY; Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.
Lee JH; Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Park JK; Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Lee DS; Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.
Jung KC; Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.
Song YW; Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Lee EB; Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea .
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Źródło:
Lupus [Lupus] 2014 Sep; Vol. 23 (10), pp. 975-85. Date of Electronic Publication: 2014 Apr 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Bone Marrow Examination*
Bone Marrow Cells/*immunology
Bone Marrow Cells/*pathology
Lupus Erythematosus, Systemic/*immunology
Lupus Erythematosus, Systemic/*pathology
Adolescent ; Adult ; Antibodies, Antinuclear/blood ; Biomarkers/analysis ; Biomarkers/blood ; Case-Control Studies ; DNA/immunology ; Dendritic Cells/immunology ; Dendritic Cells/pathology ; Female ; Humans ; Immunohistochemistry ; Interleukin-6/analysis ; Lupus Erythematosus, Systemic/blood ; Male ; Middle Aged ; Plasma Cells/immunology ; Plasma Cells/pathology ; Predictive Value of Tests ; Severity of Illness Index ; Young Adult
Czasopismo naukowe
Tytuł:
Turn-on fluorescence detection of apoptotic cells using a zinc(II)-dipicolylamine-functionalized poly(diacetylene) liposome.
Autorzy:
Cho YS; Department of Chemistry and Center for Electro-Photo Behaviors in Advanced Molecular Systems, Pohang University of Science and Technology, San 31 Hyoja-dong, Pohang 790-784, Korea.
Kim KM
Lee D
Kim WJ
Ahn KH
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Źródło:
Chemistry, an Asian journal [Chem Asian J] 2013 Apr; Vol. 8 (4), pp. 755-9. Date of Electronic Publication: 2013 Jan 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Amines/*chemistry
Liposomes/*chemistry
Picolinic Acids/*chemistry
Polymers/*chemistry
Polyynes/*chemistry
Zinc/*chemistry
Fluorescent Dyes/chemistry ; HeLa Cells ; Humans ; Microscopy, Confocal ; Phosphatidylserines/chemistry ; Polyacetylene Polymer
Czasopismo naukowe
Tytuł:
Downregulation of autophagy by Bcl-2 promotes MCF7 breast cancer cell growth independent of its inhibition of apoptosis.
Autorzy:
Oh S; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA 90033, USA.
Xiaofei E
Ni D
Pirooz SD
Lee JY
Lee D
Zhao Z
Lee S
Lee H
Ku B
Kowalik T
Martin SE
Oh BH
Jung JU
Liang C
Pokaż więcej
Źródło:
Cell death and differentiation [Cell Death Differ] 2011 Mar; Vol. 18 (3), pp. 452-64. Date of Electronic Publication: 2010 Oct 01.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Autophagy*
Down-Regulation*
Breast Neoplasms/*metabolism
Breast Neoplasms/*pathology
Proto-Oncogene Proteins c-bcl-2/*metabolism
Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Apoptosis Regulatory Proteins/metabolism ; Beclin-1 ; Breast Neoplasms/ultrastructure ; Cell Line, Tumor ; Cell Proliferation ; Cell Transformation, Neoplastic/metabolism ; Cell Transformation, Neoplastic/pathology ; DNA Damage ; Female ; Heat-Shock Proteins/metabolism ; Humans ; Membrane Proteins/metabolism ; Mice ; Mice, Nude ; Mutant Proteins/metabolism ; NIH 3T3 Cells ; Protein Binding ; Protein Structure, Secondary ; Proto-Oncogene Proteins c-bcl-2/chemistry ; Sequestosome-1 Protein ; Structure-Activity Relationship ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
Transglutaminase 2 suppresses apoptosis by modulating caspase 3 and NF-kappaB activity in hypoxic tumor cells.
Autorzy:
Jang GY; Department of Biochemistry and Molecular Biology/Aging and Apoptosis Research Center (AARC), Seoul National University College of Medicine, Seoul 110-799, Korea.
Jeon JH
Cho SY
Shin DM
Kim CW
Jeong EM
Bae HC
Kim TW
Lee SH
Choi Y
Lee DS
Park SC
Kim IG
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Źródło:
Oncogene [Oncogene] 2010 Jan 21; Vol. 29 (3), pp. 356-67. Date of Electronic Publication: 2009 Oct 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Caspase 3/*metabolism
GTP-Binding Proteins/*metabolism
NF-kappa B/*metabolism
Transglutaminases/*metabolism
Animals ; Blotting, Western ; Cell Hypoxia ; Cell Line ; Cell Line, Tumor ; Cell Survival ; GTP-Binding Proteins/chemistry ; GTP-Binding Proteins/genetics ; Gene Expression Regulation, Neoplastic ; HeLa Cells ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Mice ; Mice, Nude ; Neoplasms/genetics ; Neoplasms/metabolism ; Neoplasms/pathology ; Neoplasms, Experimental/genetics ; Neoplasms, Experimental/metabolism ; Neoplasms, Experimental/pathology ; Protein Glutamine gamma Glutamyltransferase 2 ; Protein Multimerization ; RNA Interference ; Reverse Transcriptase Polymerase Chain Reaction ; Transglutaminases/chemistry ; Transglutaminases/genetics ; Transplantation, Heterologous ; Tumor Burden
Czasopismo naukowe
Tytuł:
G1 to S phase transition protein 1 induces apoptosis signal-regulating kinase 1 activation by dissociating 14-3-3 from ASK1.
Autorzy:
Lee JA; College of Pharmacy, Chung-Ang University, Seoul, Republic of Korea.
Park JE
Lee DH
Park SG
Myung PK
Park BC
Cho S
Pokaż więcej
Źródło:
Oncogene [Oncogene] 2008 Feb 21; Vol. 27 (9), pp. 1297-305. Date of Electronic Publication: 2007 Aug 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
G1 Phase*/genetics
G1 Phase*/physiology
S Phase*/genetics
S Phase*/physiology
14-3-3 Proteins/*metabolism
Apoptosis/*physiology
MAP Kinase Kinase Kinase 5/*metabolism
Peptide Termination Factors/*physiology
14-3-3 Proteins/genetics ; 14-3-3 Proteins/physiology ; Cell Line ; Enzyme Activation/genetics ; Enzyme Activation/physiology ; HeLa Cells ; Humans ; MAP Kinase Kinase Kinase 5/antagonists & inhibitors ; MAP Kinase Signaling System/genetics ; MAP Kinase Signaling System/physiology ; Peptide Termination Factors/genetics ; Protein Binding/genetics ; Protein Binding/physiology
Czasopismo naukowe
Tytuł:
A bcl-xS adenovirus selectively induces apoptosis in transformed cells compared to normal mammary cells.
Autorzy:
Sumantran VN; Department of Internal Medicine, University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor 48109-0942, USA.
Lee DS
Woods Ignatoski KM
Ethier SP
Wicha MS
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Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2000 May-Jun; Vol. 2 (3), pp. 251-60.
Typ publikacji:
Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Apoptosis*
Adenoviridae/*genetics
Mammary Glands, Animal/*cytology
Mammary Neoplasms, Experimental/*therapy
Proto-Oncogene Proteins c-bcl-2/*physiology
Animals ; Cell Line ; Cell Transformation, Neoplastic ; Fluorouracil/pharmacology ; Genes, myc ; Humans ; Paclitaxel/pharmacology ; Proto-Oncogene Proteins c-bcl-2/genetics ; Receptor, ErbB-2/physiology ; bcl-X Protein
Czasopismo naukowe
Tytuł:
Antitumor Activity of Abnormal Cannabidiol and Its Analog O-1602 in Taxol-Resistant Preclinical Models of Breast Cancer
Autorzy:
Andrea Tomko
Lauren O’Leary
Hilary Trask
John C. Achenbach
Steven R. Hall
Kerry B. Goralski
Lee D. Ellis
Denis J. Dupré
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Temat:
cannabinoid
taxol
paclitaxel
breast cancer
apoptosis
cell migration
Therapeutics. Pharmacology
RM1-950
Źródło:
Frontiers in Pharmacology, Vol 10 (2019)
Opis pliku:
electronic resource
Relacje:
https://www.frontiersin.org/article/10.3389/fphar.2019.01124/full; https://doaj.org/toc/1663-9812
Dostęp URL:
https://doaj.org/article/6372d1fc7a684f0192e74b54ba440360  Link otwiera się w nowym oknie
Czasopismo naukowe

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