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    Wyświetlanie 1-13 z 13
    Tytuł:
    MOTILIPERM Ameliorates Immobilization Stress-Induced Testicular Dysfunction via Inhibition of Oxidative Stress and Modulation of the Nrf2/HO-1 Pathway in SD Rats.
    Autorzy:
    Karna KK; Department of Urology and Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute and Clinical Trial Center for Medical Device, Jeonbuk National University Hospital, Jeonju 54907, Korea.
    Soni KK; Department of Biological Sciences, Kent State University, Kent, OH 44242, USA.
    You JH; Department of Urology and Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute and Clinical Trial Center for Medical Device, Jeonbuk National University Hospital, Jeonju 54907, Korea.
    Choi NY; Department of Urology and Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute and Clinical Trial Center for Medical Device, Jeonbuk National University Hospital, Jeonju 54907, Korea.
    Kim HK; College of Pharmacy, Kyungsung University, Busan 48434, Korea.
    Kim CY; College of Pharmacy, Hanyang University, Ansan 426791, Korea.
    Lee SW; Department of Urology, Samsung Medical Center, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.
    Shin YS; Department of Urology and Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute and Clinical Trial Center for Medical Device, Jeonbuk National University Hospital, Jeonju 54907, Korea.
    Park JK; Department of Urology and Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute and Clinical Trial Center for Medical Device, Jeonbuk National University Hospital, Jeonju 54907, Korea.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2020 Jul 03; Vol. 21 (13). Date of Electronic Publication: 2020 Jul 03.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Plant Extracts/*pharmacology
    Testis/*drug effects
    Animals ; Apoptosis/drug effects ; Cuscuta/chemistry ; Heme Oxygenase (Decyclizing)/metabolism ; Infertility, Male/drug therapy ; Infertility, Male/pathology ; Infertility, Male/physiopathology ; Male ; Medicine, Korean Traditional ; Morinda/chemistry ; NF-E2-Related Factor 2/metabolism ; Onions/chemistry ; Oxidative Stress/drug effects ; Phytotherapy ; Plant Extracts/chemistry ; Plants, Medicinal/chemistry ; Rats ; Rats, Sprague-Dawley ; Signal Transduction/drug effects ; Sperm Motility/drug effects ; Spermatogenesis/drug effects ; Stress, Physiological ; Testis/pathology ; Testis/physiopathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Sorbaria kirilowii Ethanol Extract Exerts Anti-Inflammatory Effects In Vitro and In Vivo by Targeting Src/Nuclear Factor (NF)-κB.
    Autorzy:
    Jang J; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.; Research Institute of Biomolecule Control and Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University, Suwon 16419, Korea.
    Lee JS; DanjoungBio Co., Ltd., Wonju 26303, Korea.
    Jang YJ; College of Veterinary Medicine, Chonbuk National University, Iksan 54596, Korea.
    Choung ES; DanjoungBio Co., Ltd., Wonju 26303, Korea.
    Li WY; Institute of Medicinal Plants, Yunnan Academy of Agricultural Sciences, Kunming 650224, China.
    Lee SW; International Biological Material Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.
    Kim E; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
    Kim JH; College of Veterinary Medicine, Chonbuk National University, Iksan 54596, Korea.
    Cho JY; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.; Research Institute of Biomolecule Control and Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University, Suwon 16419, Korea.
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    Źródło:
    Biomolecules [Biomolecules] 2020 May 10; Vol. 10 (5). Date of Electronic Publication: 2020 May 10.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Anti-Inflammatory Agents/*pharmacology
    Ethanol/*chemistry
    NF-kappa B/*metabolism
    Plant Extracts/*pharmacology
    Rosaceae/*chemistry
    src-Family Kinases/*antagonists & inhibitors
    Animals ; Gastritis/drug therapy ; Gastritis/metabolism ; Gastritis/pathology ; HEK293 Cells ; Humans ; Inflammation/genetics ; Inflammation/pathology ; Male ; Mice ; Mice, Inbred ICR ; Models, Biological ; Nitric Oxide/biosynthesis ; RAW 264.7 Cells ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Signal Transduction/drug effects ; Transcription, Genetic/drug effects ; src-Family Kinases/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Src/NF-κB-Targeted Anti-Inflammatory Effects of Potentilla glabra var. Mandshurica (Maxim.) Hand.-Mazz. Ethanol Extract.
    Autorzy:
    Kim H; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
    Shin KK; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
    Kim HG; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.; Research Institute of Biomolecule Control and Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University, Suwon 16419, Korea.
    Jo M; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
    Kim JK; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
    Lee JS; DanjoungBio Co., Ltd., Wonju 26303, Korea.
    Choung ES; DanjoungBio Co., Ltd., Wonju 26303, Korea.
    Li WY; Institute of Medicinal Plants, Yunnan Academy of Agricultural Sciences; Yunnan 650224, China.
    Lee SW; International Biological Material Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.
    Kim KH; Biomarker Branch, Research Institute, National Cancer Center, Goyang 10408, Korea.
    Yoo BC; Biomarker Branch, Research Institute, National Cancer Center, Goyang 10408, Korea.
    Cho JY; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.; Research Institute of Biomolecule Control and Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University, Suwon 16419, Korea.
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    Źródło:
    Biomolecules [Biomolecules] 2020 Apr 22; Vol. 10 (4). Date of Electronic Publication: 2020 Apr 22.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Anti-Inflammatory Agents/*pharmacology
    Ethanol/*chemistry
    NF-kappa B/*antagonists & inhibitors
    Plant Extracts/*pharmacology
    Potentilla/*chemistry
    src-Family Kinases/*antagonists & inhibitors
    Acute Disease ; Animals ; Gastritis/pathology ; HEK293 Cells ; Humans ; Male ; Mice ; Mice, Inbred ICR ; Models, Biological ; NF-kappa B/metabolism ; Nitric Oxide/biosynthesis ; RAW 264.7 Cells ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Transcription, Genetic/drug effects ; src-Family Kinases/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Protective effect of MOTILIPERM in varicocele-induced oxidative injury in rat testis by activating phosphorylated inositol requiring kinase 1α (p-IRE1α) and phosphorylated c-Jun N-terminal kinase (p-JNK) pathways.
    Autorzy:
    Soni KK; a Department of Urology , Chonbuk National University and Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University , Jeonju , Republic of Korea.
    Zhang LT; a Department of Urology , Chonbuk National University and Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University , Jeonju , Republic of Korea.
    Choi BR; a Department of Urology , Chonbuk National University and Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University , Jeonju , Republic of Korea.
    Karna KK; a Department of Urology , Chonbuk National University and Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University , Jeonju , Republic of Korea.
    You JH; a Department of Urology , Chonbuk National University and Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University , Jeonju , Republic of Korea.
    Shin YS; a Department of Urology , Chonbuk National University and Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University , Jeonju , Republic of Korea.
    Lee SW; b Department of Urology , Samsung Medical Center, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine , Seoul , Republic of Korea.
    Kim CY; c College of Pharmacy , Hanyang University , Ansan , Republic of Korea.
    Zhao C; d Department of Urology , Renji Hospital, Shanghai Jiao Tong University School of Medicine, and Shanghai Institute of Andrology , Shanghai , China.
    Chae HJ; e Department of Pharmacology , Chonbuk University of Medical School , Jeonju , Republic of Korea.
    Kim HK; f College of Pharmacy , Kyungsung University , Busan , Republic of Korea.
    Park JK; a Department of Urology , Chonbuk National University and Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University , Jeonju , Republic of Korea.
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    Źródło:
    Pharmaceutical biology [Pharm Biol] 2018 Dec; Vol. 56 (1), pp. 94-103.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Antioxidants/*therapeutic use
    Endoribonucleases/*metabolism
    JNK Mitogen-Activated Protein Kinases/*metabolism
    Multienzyme Complexes/*metabolism
    Plant Extracts/*therapeutic use
    Protein Serine-Threonine Kinases/*metabolism
    Varicocele/*metabolism
    Varicocele/*prevention & control
    Animals ; Antioxidants/isolation & purification ; Antioxidants/pharmacology ; Male ; Phosphorylation/drug effects ; Phosphorylation/physiology ; Plant Extracts/isolation & purification ; Plant Extracts/pharmacology ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species/antagonists & inhibitors ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects ; Signal Transduction/physiology ; Testis/drug effects ; Testis/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Inhibitory Effects of Compounds and Extracts from Ampelopsis brevipedunculata on IL-6-Induced STAT3 Activation.
    Autorzy:
    Jang HJ; Immunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Republic of Korea.
    Lee SJ; Immunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Republic of Korea.
    Lim HJ; Immunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Republic of Korea.
    Jung K; Immunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Republic of Korea.
    Lee S; Immunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Republic of Korea.
    Park CS; Immunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Republic of Korea.
    Lee SW; Immunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Republic of Korea.
    Rho MC; Immunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Republic of Korea.
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    Źródło:
    BioMed research international [Biomed Res Int] 2018 Jun 10; Vol. 2018, pp. 3684845. Date of Electronic Publication: 2018 Jun 10 (Print Publication: 2018).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Ampelopsis/*chemistry
    Interleukin-6/*metabolism
    Plant Extracts/*pharmacology
    STAT3 Transcription Factor/*drug effects
    Cell Line ; Humans ; Phosphorylation
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Effects of eupatilin on the contractility of corpus cavernosal smooth muscle through nitric oxide-independent pathways.
    Autorzy:
    Choo SH; Department of Urology, Ajou University School of Medicine, Suwon, Korea.
    Lee SW; Department of Urology, Samsung Medical Center, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea.
    Chae MR; Department of Urology, Samsung Medical Center, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea.
    Kang SJ; Department of Urology, Samsung Medical Center, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea.
    Sung HH; Department of Urology, Samsung Medical Center, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea.
    Han DH; Department of Urology, Samsung Medical Center, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea.
    Chun JN; Department of Physiology and Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.
    Park JK; Department of Urology, Institute for Medical Sciences, Medical School, Chonbuk National University, Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University Hospital, Jeonju, Korea.
    Kim CY; College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, Korea.
    Kim HK; College of Pharmacy, Kyungsung University, Busan, Korea.
    So I; Department of Physiology, Seoul National University College of Medicine, Seoul, Korea.
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    Źródło:
    Andrology [Andrology] 2017 Sep; Vol. 5 (5), pp. 1016-1022. Date of Electronic Publication: 2017 Jul 18.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Artemisia/*chemistry
    Flavonoids/*pharmacology
    Muscle Contraction/*drug effects
    Myocytes, Smooth Muscle/*drug effects
    Nitric Oxide/*metabolism
    Penis/*drug effects
    Plant Extracts/*pharmacology
    Animals ; Cells, Cultured ; Humans ; In Vitro Techniques ; Intracellular Signaling Peptides and Proteins ; Male ; Muscle Proteins ; Myosin-Light-Chain Phosphatase/metabolism ; Penile Erection/drug effects ; Penis/metabolism ; Phosphoprotein Phosphatases/metabolism ; Phosphorylation ; Pilot Projects ; Potassium Channels, Calcium-Activated/metabolism ; Rabbits ; Threonine/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Onion (Allium cepa L.) peel extract (OPE) regulates human sperm motility via protein kinase C-mediated activation of the human voltage-gated proton channel.
    Autorzy:
    Chae MR; Department of Urology, Samsung Medical Center, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea.
    Kang SJ; Department of Urology, Samsung Medical Center, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea.
    Lee KP; Laboratory of Physiology, College of Veterinary Medicine, Chungnam National University, Daejeon, Korea.
    Choi BR; Department of Urology, Medical School and Institute for Medical Sciences, Chonbuk National University, Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University Hospital, Jeonju, Korea.
    Kim HK; College of Pharmacy, Kyungsung University, Busan, Korea.
    Park JK; Department of Urology, Medical School and Institute for Medical Sciences, Chonbuk National University, Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University Hospital, Jeonju, Korea.
    Kim CY; College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, Korea.
    Lee SW; Department of Urology, Samsung Medical Center, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea.
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    Źródło:
    Andrology [Andrology] 2017 Sep; Vol. 5 (5), pp. 979-989. Date of Electronic Publication: 2017 Aug 13.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Antioxidants/*pharmacology
    Ion Channels/*metabolism
    Onions/*chemistry
    Plant Extracts/*pharmacology
    Protein Kinase C/*metabolism
    Enzyme Inhibitors/pharmacology ; HEK293 Cells ; Humans ; Indoles/pharmacology ; Male ; Maleimides/pharmacology ; Protein Kinase C/antagonists & inhibitors ; Quercetin/pharmacology ; Sperm Motility/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Effect of Sunlight Radiation on the Growth and Chemical Constituents of Salvia plebeia R.Br.
    Autorzy:
    Jang HJ; Immunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Korea. .
    Lee SJ; Immunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Korea. .
    Kim CY; Biological Resource Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Korea. .
    Hwang JT; Immunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Korea. .
    Choi JH; R&D Center, Korean Drug Co., Ltd., Seoul 06300, Korea. .
    Park JH; R&D Center, Korean Drug Co., Ltd., Seoul 06300, Korea. .
    Lee SW; Immunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Korea. .
    Rho MC; Immunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Korea. .
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    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2017 Aug 01; Vol. 22 (8). Date of Electronic Publication: 2017 Aug 01.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Sunlight*
    Plant Extracts/*chemistry
    Salvia/*radiation effects
    Animals ; Antioxidants/chemistry ; Antioxidants/pharmacology ; Chromatography, High Pressure Liquid ; Flavonoids/chemistry ; Humans ; Mice ; Molecular Structure ; Oleanolic Acid/chemistry ; Oleanolic Acid/pharmacology ; Phenols/chemistry ; Photosynthesis ; RAW 264.7 Cells ; Salvia/chemistry ; Salvia/growth & development ; Triterpenes/chemistry ; Triterpenes/pharmacology ; Ursolic Acid
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Study of the UV Light Conversion of Feruloyl Amides from Portulaca oleracea and Their Inhibitory Effect on IL-6-Induced STAT3 Activation.
    Autorzy:
    Hwang JT; Natural Product Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Korea. .
    Kim Y; Natural Product Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Korea. .
    Jang HJ; Natural Product Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Korea. .
    Oh HM; Natural Product Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Korea. .
    Lim CH; College of Agriculture and Life Sciences, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 300-764, Korea. .
    Lee SW; Natural Product Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Korea. .
    Rho MC; Natural Product Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Korea. .
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    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2016 Jun 30; Vol. 21 (7). Date of Electronic Publication: 2016 Jun 30.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Amides/*chemistry
    Amides/*pharmacology
    Interleukin-6/*metabolism
    Plant Extracts/*chemistry
    Plant Extracts/*pharmacology
    Portulaca/*chemistry
    STAT3 Transcription Factor/*metabolism
    Cell Line, Tumor ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Humans ; Interleukin-6/pharmacology ; Janus Kinase 2/metabolism ; Magnetic Resonance Spectroscopy ; Molecular Structure ; Phosphorylation/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Additive effects of Artemisia capillaris extract and scopoletin on the relaxation of penile corpus cavernosum smooth muscle.
    Autorzy:
    Choi BR; Department of Urology, Chonbuk National University and Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University, Jeonju, Republic of Korea.
    Kumar SK; Department of Urology, Chonbuk National University and Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University, Jeonju, Republic of Korea.
    Zhao C; Department of Urology, Renji Hospital, Jiao Tong University School of Medicine, and Shanghai Institute of Andrology, Shanghai, China.
    Zhang LT; Department of Urology, Chonbuk National University and Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University, Jeonju, Republic of Korea.
    Kim CY; Department of Pharmacognosy, Hangyang University, Ansan, Republic of Korea.
    Lee SW; Department of Urology, Sungkyunkwan University Medical School, Seoul, Republic of Korea.
    Jeon JH; Department of Physiology, Seoul National University Medical School, Seoul, Republic of Korea.
    Soní KK
    Kim SH; Department of Physiology, Diabetic Research Center, Chonbuk National University Medical School, Jeonju, Republic of Korea.
    Park NC; Department of Urology, Pusan National University Hospital, Busan, Republic of Korea.
    Kim HK; Department of Urology, Chonbuk National University and Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University, Jeonju, Republic of Korea.
    Park JK; Department of Urology, Chonbuk National University and Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University, Jeonju, Republic of Korea.
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    Źródło:
    International journal of impotence research [Int J Impot Res] 2015 Nov-Dec; Vol. 27 (6), pp. 225-32. Date of Electronic Publication: 2015 Oct 08.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Artemisia/*chemistry
    Muscle Relaxation/*drug effects
    Muscle, Smooth/*drug effects
    Penis/*drug effects
    Plant Extracts/*pharmacology
    Scopoletin/*pharmacology
    Animals ; Blotting, Western ; Cyclic AMP/analysis ; Cyclic GMP/analysis ; Drug Interactions ; Male ; Nitric Oxide Synthase Type I/genetics ; Nitric Oxide Synthase Type III/analysis ; Phosphodiesterase 5 Inhibitors/pharmacology ; Pyrimidines/pharmacology ; RNA, Messenger/analysis ; Rabbits ; Real-Time Polymerase Chain Reaction ; Sulfonamides/pharmacology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Protective effect of the aqueous extract from the root of Platycodon grandiflorum on cholestasis-induced hepatic injury in mice.
    Autorzy:
    Kim TW; College of Veterinary Medicine, Chungnam National University , Gung-dong, Yuseong-gu, Daejeon, Korea.
    Lee HK
    Song IB
    Kim MS
    Hwang YH
    Lim JH
    Park SJ
    Lee SW
    Kim JW
    Yun HI
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    Źródło:
    Pharmaceutical biology [Pharm Biol] 2012 Dec; Vol. 50 (12), pp. 1473-8. Date of Electronic Publication: 2012 Oct 04.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Platycodon*/chemistry
    Cholestasis, Extrahepatic/*drug therapy
    Liver/*drug effects
    Liver Diseases/*prevention & control
    Plant Extracts/*pharmacology
    Protective Agents/*pharmacology
    Alanine Transaminase/blood ; Animals ; Aspartate Aminotransferases/blood ; Biomarkers/blood ; Cholestasis, Extrahepatic/blood ; Cholestasis, Extrahepatic/etiology ; Cholestasis, Extrahepatic/pathology ; Chromatography, High Pressure Liquid ; Common Bile Duct/surgery ; Cytoprotection ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Glutathione/metabolism ; Ligation ; Liver/enzymology ; Liver/pathology ; Liver Diseases/blood ; Liver Diseases/etiology ; Liver Diseases/pathology ; Male ; Malondialdehyde/metabolism ; Mice ; Mice, Inbred ICR ; Nitric Oxide/metabolism ; Plant Extracts/analysis ; Plant Extracts/isolation & purification ; Plant Roots ; Plants, Medicinal ; Protective Agents/analysis ; Protective Agents/isolation & purification ; Superoxide Dismutase/metabolism ; Thiobarbituric Acid Reactive Substances/metabolism ; Time Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Effects of Schisandra chinensis extract on the contractility of corpus cavernosal smooth muscle (CSM) and Ca2+ homeostasis in CSM cells.
    Autorzy:
    Han DH; Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
    Lee JH
    Kim H
    Ko MK
    Chae MR
    Kim HK
    So I
    Jeon JH
    Park JK
    Lee SW
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    Źródło:
    BJU international [BJU Int] 2012 May; Vol. 109 (9), pp. 1404-13. Date of Electronic Publication: 2011 Sep 27.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Fruit/*chemistry
    Muscle Contraction/*drug effects
    Muscle, Smooth/*drug effects
    Penis/*drug effects
    Plant Extracts/*pharmacology
    Schisandra/*chemistry
    Animals ; Dose-Response Relationship, Drug ; Fluorescent Dyes ; Fura-2 ; In Vitro Techniques ; Male ; Patch-Clamp Techniques ; Potassium Channels, Calcium-Activated/drug effects ; Potassium Channels, Inwardly Rectifying/drug effects ; Rabbits ; TRPC Cation Channels/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Cytokine production regulation in human astrocytes by a herbal combination (Yuldahansotang).
    Autorzy:
    Choi JS; College of Oriental Medicine, Center of Oriental Medicinal Science, Wonkwang University, Iksan-city, Chonbuk, Republic of Korea.
    Jung SW
    Ju JC
    Lee SW
    Kim KY
    Kim HM
    Pokaż więcej
    Źródło:
    Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2002 Feb; Vol. 24 (1), pp. 55-67.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Astrocytes/*drug effects
    Interleukin-1/*metabolism
    Plant Extracts/*pharmacology
    Tumor Necrosis Factor-alpha/*metabolism
    Astrocytes/cytology ; Astrocytes/metabolism ; Cell Line ; Dose-Response Relationship, Drug ; Down-Regulation ; Humans ; Lipopolysaccharides/pharmacology ; Medicine, East Asian Traditional ; Plants, Medicinal ; Substance P/pharmacology
    Czasopismo naukowe
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