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Wyszukujesz frazę ""Leflunomide"" wg kryterium: Temat


Tytuł :
Leflunomide an immunomodulator with antineoplastic and antiviral potentials but drug-induced liver injury: A comprehensive review.
Autorzy :
Alamri RD; Faculty of Medicine, University of Tabuk, Tabuk 47713, Saudi Arabia.
Elmeligy MA; Faculty of Medicine, Cairo University, Cairo 11562, Egypt.
Albalawi GA; Faculty of Medicine, University of Tabuk, Tabuk 47713, Saudi Arabia.
Alquayr SM; Faculty of Medicine, University of Tabuk, Tabuk 47713, Saudi Arabia.
Alsubhi SS; Faculty of Medicine, University of Tabuk, Tabuk 47713, Saudi Arabia.
El-Ghaiesh SH; Deaprtment of Pharmacology, Faculty of Medicine, Tanta University, Tanta 31527, Egypt; Department of Pharmacology, Faculty of Medicine, University of Tabuk, Tabuk 47713, Saudi Arabia. Electronic address: .
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Źródło :
International immunopharmacology [Int Immunopharmacol] 2021 Apr; Vol. 93, pp. 107398. Date of Electronic Publication: 2021 Feb 08.
Typ publikacji :
Journal Article; Review
MeSH Terms :
COVID-19/*drug therapy
Leflunomide/*adverse effects
Leflunomide/*therapeutic use
Antineoplastic Agents/adverse effects ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Antiviral Agents/adverse effects ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Chemical and Drug Induced Liver Injury/drug therapy ; Clinical Trials as Topic ; Humans ; Immunologic Factors/adverse effects ; Immunologic Factors/pharmacology ; Immunologic Factors/therapeutic use ; Leflunomide/pharmacology ; SARS-CoV-2/isolation & purification
Czasopismo naukowe
Tytuł :
Efficacy of leflunomide combined with prednisone for the treatment of PLA2R-associated primary membranous nephropathy.
Autorzy :
Guo Y; Department of Nephrology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, People's Republic of China.
Wu X; Department of Nephrology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, People's Republic of China.
Liu L; Department of Nephrology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, People's Republic of China.
Zhang H; Department of Nephrology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, People's Republic of China.
Yang L; Department of Nephrology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, People's Republic of China.
Chen W; Department of Nephrology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, People's Republic of China.
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Źródło :
Renal failure [Ren Fail] 2020 Nov; Vol. 42 (1), pp. 122-130.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Glomerulonephritis, Membranous/*complications
Glomerulonephritis, Membranous/*drug therapy
Leflunomide/*therapeutic use
Nephrotic Syndrome/*complications
Prednisone/*therapeutic use
Adult ; Autoantibodies/blood ; Biomarkers/blood ; Cyclophosphamide/therapeutic use ; Drug Therapy, Combination ; Female ; Humans ; Immunosuppressive Agents/therapeutic use ; Leflunomide/adverse effects ; Male ; Middle Aged ; Prednisone/adverse effects ; Proteinuria/drug therapy ; Receptors, Phospholipase A2/immunology ; Remission Induction ; Serum Albumin
Czasopismo naukowe
Tytuł :
Biological and targeted-synthetic disease-modifying anti-rheumatic drugs with concomitant methotrexate or leflunomide in rheumatoid arthritis: real-life TReasure prospective data.
Autorzy :
Kimyon G; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Hatay, Hatay Mustafa Kemal University, Turkey.
Kalyoncu U; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Division of Rheumatology, Hacettepe University, Ankara, Turkey. .
Kiraz S; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Division of Rheumatology, Hacettepe University, Ankara, Turkey.
Bes C; Division of Rheumatology, Department of Internal Medicine, University of Health Sciences, Bakırkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Coşkun N; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Uludag University, Bursa, Turkey.
Yağiz B; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Uludag University, Bursa, Turkey.
Küçükşahin O; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Yıldırım Beyazıt University, Ankara, Turkey.
Kanitez N; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Koc University, Istanbul, Turkey.
Erden A; Division of Rheumatology, Department of Internal Medicine, Ankara City Hospital, Ankara, Turkey.
Kiliç L; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Division of Rheumatology, Hacettepe University, Ankara, Turkey.
Bilgin E; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Division of Rheumatology, Hacettepe University, Ankara, Turkey.
Kaşifoğlu T; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey.
Emmungil H; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Trakya University, Edirne, Turkey.
Koca SS; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Firat University, Elazig, Turkey.
Akar S; Division of Rheumatology, Department of Internal Medicine, Izmir Katip Celebi University School of Medicine, Izmir, Turkey.
Çinar M; Division of Rheumatology, Department of Internal Medicine, Gulhane Faculty of Medicine, University of Health Sciences, Ankara, Turkey.
Yazisiz V; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Akdeniz University, Antalya, Turkey.
Ateş A; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Ankara University, Ankara, Turkey.
Ersözlü D; Division of Rheumatology, Department of Internal Medicine, Ministry of Health Adana City Training and Research Hospital, Adana, Turkey.
Gönüllü E; Division of Rheumatology, Department of Internal Medicine, Sakarya University, Sakarya, Turkey.
Mercan R; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Tekirdag Namik Kemal University, Tekirdag, Turkey.
Ertenli İ; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Division of Rheumatology, Hacettepe University, Ankara, Turkey.
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Źródło :
Clinical and experimental rheumatology [Clin Exp Rheumatol] 2021 Jul-Aug; Vol. 39 (4), pp. 852-858. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji :
Journal Article
MeSH Terms :
Antirheumatic Agents*/adverse effects
Arthritis, Rheumatoid*/diagnosis
Arthritis, Rheumatoid*/drug therapy
Drug Therapy, Combination ; Female ; Humans ; Leflunomide/therapeutic use ; Methotrexate/adverse effects ; Prospective Studies ; Treatment Outcome ; Tumor Necrosis Factor Inhibitors ; Turkey
Czasopismo naukowe
Tytuł :
Reply to DeVito.
Autorzy :
Wang M; Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, China.
Hu K; Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, China.
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Źródło :
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2021 Jun 15; Vol. 72 (12), pp. e1165-e1166.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
COVID-19*
Humans ; Leflunomide ; SARS-CoV-2 ; Virus Shedding
Raport
Tytuł :
Therapeutic management in paediatric alopecia areata: A systematic review.
Autorzy :
Waśkiel-Burnat A; Department of Dermatology, Medical University of Warsaw, Warsaw, Poland.
Kołodziejak M; Department of Dermatology, Medical University of Warsaw, Warsaw, Poland.
Sikora M; Department of Dermatology, Medical University of Warsaw, Warsaw, Poland.
Stochmal A; Department of Dermatology, Medical University of Warsaw, Warsaw, Poland.
Rakowska A; Department of Dermatology, Medical University of Warsaw, Warsaw, Poland.
Olszewska M; Department of Dermatology, Medical University of Warsaw, Warsaw, Poland.
Rudnicka L; Department of Dermatology, Medical University of Warsaw, Warsaw, Poland.
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Źródło :
Journal of the European Academy of Dermatology and Venereology : JEADV [J Eur Acad Dermatol Venereol] 2021 Jun; Vol. 35 (6), pp. 1299-1308.
Typ publikacji :
Journal Article; Review; Systematic Review
MeSH Terms :
Alopecia Areata*/drug therapy
Janus Kinase Inhibitors*
Adolescent ; Alopecia ; Child ; Humans ; Leflunomide ; Minoxidil ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis.
Autorzy :
Rossmann MP; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 01238, USA.; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA.
Hoi K; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 01238, USA.; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA.
Chan V; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 01238, USA.; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA.
Abraham BJ; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.
Yang S; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA.
Mullahoo J; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Papanastasiou M; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Wang Y; Department of Biology, McGill University, Montréal, Québec H3A 1B1, Canada.
Elia I; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
Perlin JR; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA.
Hagedorn EJ; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA.
Hetzel S; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany.
Weigert R; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany.
Vyas S; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
Nag PP; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Sullivan LB; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Warren CR; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Dorjsuren B; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 01238, USA.; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA.
Greig EC; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 01238, USA.; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA.
Adatto I; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 01238, USA.; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA.
Cowan CA; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Schreiber SL; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Young RA; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Meissner A; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 01238, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany.
Haigis MC; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
Hekimi S; Department of Biology, McGill University, Montréal, Québec H3A 1B1, Canada.
Carr SA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Zon LI; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 01238, USA. .; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2021 May 14; Vol. 372 (6543), pp. 716-721.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Erythropoiesis*
Transcription, Genetic*
Mitochondria/*metabolism
Transcription Factors/*metabolism
Zebrafish Proteins/*metabolism
Animals ; Citric Acid Cycle ; DNA Methylation ; Electron Transport ; Embryo, Nonmammalian/metabolism ; Enzyme Inhibitors/pharmacology ; Gene Expression Regulation ; Histones/metabolism ; Leflunomide/pharmacology ; Metabolic Networks and Pathways ; Methylation ; Oxidoreductases Acting on CH-CH Group Donors/antagonists & inhibitors ; Oxygen Consumption ; Transcription Factors/genetics ; Ubiquinone/metabolism ; Zebrafish/embryology ; Zebrafish/genetics ; Zebrafish Proteins/genetics
Czasopismo naukowe
Tytuł :
Effect of Half-Dose vs Stable-Dose Conventional Synthetic Disease-Modifying Antirheumatic Drugs on Disease Flares in Patients With Rheumatoid Arthritis in Remission: The ARCTIC REWIND Randomized Clinical Trial.
Autorzy :
Lillegraven S; Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.
Paulshus Sundlisæter N; Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.
Aga AB; Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.
Sexton J; Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.
Olsen IC; Clinical Trial Unit, Oslo University Hospital, Oslo, Norway.
Fremstad H; Department of Rheumatology, Ålesund Hospital, Helse Møre og Romsdal HF, Ålesund, Norway.
Spada C; Revmatismesykehuset AS, Lillehammer, Norway.
Madland TM; Department of Rheumatology, Haukeland University Hospital, Bergen, Norway.
Høili CA; Department of Rheumatology, Hospital Østfold HF, Moss, Norway.
Bakland G; Department of Rheumatology, University Hospital of North Norway, Tromsø, Norway.
Lexberg Å; Department of Rheumatology, Drammen Hospital, Vestre Viken HF, Drammen, Norway.
Hansen IJW; Department of Rheumatology, Sørlandet Hospital HF, Kristiansand, Norway.
Hansen IM; Department of Rheumatology, Helgelandssykehuset Mo i Rana, Mo i Rana, Norway.
Haukeland H; Department of Rheumatology, Martina Hansens Hospital, Bærum, Norway.
Ljoså MA; Department of Rheumatology, Ålesund Hospital, Helse Møre og Romsdal HF, Ålesund, Norway.
Moholt E; Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.
Uhlig T; Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.; Faculty of Medicine, University of Oslo, Oslo, Norway.
Solomon DH; Division of Rheumatology, Brigham and Women's Hospital, Boston, Massachusetts.
van der Heijde D; Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.; Department of Rheumatology, Leiden University Medical Centre, Leiden, the Netherlands.
Kvien TK; Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.; Faculty of Medicine, University of Oslo, Oslo, Norway.
Haavardsholm EA; Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.; Faculty of Medicine, University of Oslo, Oslo, Norway.
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Źródło :
JAMA [JAMA] 2021 May 04; Vol. 325 (17), pp. 1755-1764.
Typ publikacji :
Equivalence Trial; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Symptom Flare Up*
Antirheumatic Agents/*administration & dosage
Arthritis, Rheumatoid/*drug therapy
Methotrexate/*administration & dosage
Adult ; Aged ; Antirheumatic Agents/adverse effects ; Arthritis, Rheumatoid/diagnostic imaging ; Arthritis, Rheumatoid/pathology ; Dose-Response Relationship, Drug ; Drug Therapy, Combination ; Female ; Humans ; Hydroxychloroquine/administration & dosage ; Leflunomide/administration & dosage ; Male ; Methotrexate/adverse effects ; Middle Aged ; Radiography ; Sulfasalazine/administration & dosage ; Ultrasonography
Czasopismo naukowe
Tytuł :
Comparison of the efficacy of cyclosporine and leflunomide in treating inflammatory colorectal polyps in miniature dachshunds.
Autorzy :
Tani A; Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Seno T; Veterinary Medical Center, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Yokoyama N; Veterinary Medical Center, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Nakagawa T; Veterinary Medical Center, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Tomiyasu H; Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Goto-Koshino Y; Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Tsujimoto H; Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Ohno K; Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
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Źródło :
The Journal of veterinary medical science [J Vet Med Sci] 2020 Apr 09; Vol. 82 (4), pp. 437-440. Date of Electronic Publication: 2020 Feb 14.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Colonic Polyps/*veterinary
Cyclosporine/*therapeutic use
Immunosuppressive Agents/*therapeutic use
Leflunomide/*therapeutic use
Animals ; Colonic Polyps/drug therapy ; Dog Diseases/drug therapy ; Dogs ; Female ; Immunosuppressive Agents/adverse effects ; Japan ; Leflunomide/adverse effects ; Male ; Recurrence ; Retrospective Studies ; Treatment Outcome
Czasopismo naukowe
Tytuł :
The role of Chinese herbal medicine in the management of adverse drug reactions of leflunomide in treating rheumatoid arthritis.
Autorzy :
Wang W; Faculty of Chinese Medicine/State Key Laboratory of Quality Research in Chinese Medicine/Institute of Rheumatic Diseases, Macau University of Science and Technology, Avenida Wailong, Taipa, Macau, PR China.
Zhou H; Faculty of Chinese Medicine/State Key Laboratory of Quality Research in Chinese Medicine/Institute of Rheumatic Diseases, Macau University of Science and Technology, Avenida Wailong, Taipa, Macau, PR China; Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, PR China.
Liu L; Faculty of Chinese Medicine/State Key Laboratory of Quality Research in Chinese Medicine/Institute of Rheumatic Diseases, Macau University of Science and Technology, Avenida Wailong, Taipa, Macau, PR China. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2020 Mar; Vol. 68, pp. 153136. Date of Electronic Publication: 2019 Nov 18.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antirheumatic Agents/*adverse effects
Arthritis, Rheumatoid/*drug therapy
Drugs, Chinese Herbal/*therapeutic use
Leflunomide/*adverse effects
Antirheumatic Agents/therapeutic use ; Herb-Drug Interactions ; Humans ; Leflunomide/therapeutic use
Czasopismo naukowe
Tytuł :
Comparing methotrexate monotherapy with methotrexate plus leflunomide combination therapy in psoriatic arthritis: protocol of a randomized, placebo-controlled, double-blind clinical trial (COMPLETE-PsA).
Autorzy :
Mulder MLM; Department of Rheumatology, Sint Maartenskliniek, PO Box 9011, Nijmegen, 6500 GM, The Netherlands. .; Department of Rheumatic Diseases, Radboud University Medical Center, Nijmegen, The Netherlands. .
Vriezekolk JE; Department of Rheumatology, Sint Maartenskliniek, PO Box 9011, Nijmegen, 6500 GM, The Netherlands.
den Broeder N; Department of Rheumatology, Sint Maartenskliniek, PO Box 9011, Nijmegen, 6500 GM, The Netherlands.
Mahler EAM; Department of Rheumatology, Sint Maartenskliniek, PO Box 9011, Nijmegen, 6500 GM, The Netherlands.
Helliwell PS; Leeds Institute of Rheumatology and Musculoskeletal Medicine, University of Leeds, Leeds, UK.
van den Hoogen FHJ; Department of Rheumatology, Sint Maartenskliniek, PO Box 9011, Nijmegen, 6500 GM, The Netherlands.; Department of Rheumatic Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
den Broeder AA; Department of Rheumatology, Sint Maartenskliniek, PO Box 9011, Nijmegen, 6500 GM, The Netherlands.; Department of Rheumatic Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Wenink MH; Department of Rheumatology, Sint Maartenskliniek, PO Box 9011, Nijmegen, 6500 GM, The Netherlands.
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Źródło :
Trials [Trials] 2020 Feb 10; Vol. 21 (1), pp. 155. Date of Electronic Publication: 2020 Feb 10.
Typ publikacji :
Clinical Trial Protocol; Journal Article
MeSH Terms :
Antirheumatic Agents/*administration & dosage
Arthritis, Psoriatic/*drug therapy
Immunosuppressive Agents/*administration & dosage
Leflunomide/*administration & dosage
Methotrexate/*administration & dosage
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antirheumatic Agents/adverse effects ; Double-Blind Method ; Drug Therapy, Combination ; Female ; Humans ; Immunosuppressive Agents/adverse effects ; Leflunomide/adverse effects ; Male ; Methotrexate/adverse effects ; Middle Aged ; Quality of Life ; Randomized Controlled Trials as Topic ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Efficacy and safety of leflunomide treatment in Takayasu arteritis: Case series from the East China cohort.
Autorzy :
Cui X; Department of Rheumatology, Zhongshan Hospital, Fudan University, No. 180, Road Fenglin, Shanghai 200032, China.
Dai X; Department of Rheumatology, Zhongshan Hospital, Fudan University, No. 180, Road Fenglin, Shanghai 200032, China.
Ma L; Department of Rheumatology, Zhongshan Hospital, Fudan University, No. 180, Road Fenglin, Shanghai 200032, China.
Yang C; Department of Rheumatology, Ruijin Hospital, Shanghai Jiaotong University Medical College, Shanghai, China.
Tan W; Department of Rheumatology, The First Affiliated Hospital, Nanjing Medical University, Jiangsu Province, China.
Zhang L; Department of Rheumatology, Second Hospital of Shanxi Medical University, Shanxi Province, China.
Zhang Z; Department of Rheumatology, Linyi People's Hospital, Shandong Province, China.
Feng X; Department of Rheumatology, Nanjing Drum Tower Hospital, Nanjing University Medical School, Jiangsu Province, China.
Wu R; Department of Rheumatology, The First Affiliated Hospital, Nanchang University, Jiangxi Province, China.
Zou Y; Department of Rheumatology, Wuxi People's Hospital, Nanjing Medical University, Jiangsu Province, China.
Zhou Z; Department of Rheumatology, Renji Hospital, Shanghai Jiaotong University Medical College, Shanghai, China.
Lu Y; Department of Rheumatology, Renji Hospital, Shanghai Jiaotong University Medical College, Shanghai, China.
Wang Y; Department of Rheumatology, Jiangxi Provincial People's Hospital, Jiangxi Province, China.
Wu M; Department of Rheumatology, The Third People's Hospital of Changzhou, Soochow University, Jiangsu Province, China.
Li S; Department of Rheumatology, Wenzhou Central Hospital, Zhejiang Province, China.
Wang L; Department of Rheumatology, Zaozhuang Municipal Hospital, Shandong Province, China.
Lin H; Department of Rheumatology, Fujian Provincial Hospital, Fujian Province, China.
Dong Z; Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Fu W; Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Sun X; Department of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Wang C; Department of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Ding J; Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai, China.
Lv P; Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Lin J; Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Jiang L; Department of Rheumatology, Zhongshan Hospital, Fudan University, No. 180, Road Fenglin, Shanghai 200032, China; Evidence-Based Medicine Center, Fudan University, Shanghai, China. Electronic address: .
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Corporate Authors :
East China Takayasu Arteritis (ECTA) Collaboration Group
Źródło :
Seminars in arthritis and rheumatism [Semin Arthritis Rheum] 2020 Feb; Vol. 50 (1), pp. 59-65. Date of Electronic Publication: 2019 Jun 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cyclophosphamide/*therapeutic use
Immunosuppressive Agents/*therapeutic use
Leflunomide/*therapeutic use
Takayasu Arteritis/*drug therapy
Adolescent ; Adult ; China ; Cyclophosphamide/adverse effects ; Disease Progression ; Female ; Humans ; Immunosuppressive Agents/adverse effects ; Leflunomide/adverse effects ; Magnetic Resonance Angiography ; Male ; Remission Induction ; Takayasu Arteritis/diagnostic imaging ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Leflunomide increased the renal exposure of acyclovir by inhibiting OAT1/3 and MRP2.
Autorzy :
Liao XY; State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, 210009, China.
Deng QQ; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Han L; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Wu ZT; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Peng ZL; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Xie Y; State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, 210009, China.
Wang GJ; State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, 210009, China.
Aa JY; State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, 210009, China. .
Pan GY; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. .; University of Chinese Academy of Sciences, Beijing, 100049, China. .
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Źródło :
Acta pharmacologica Sinica [Acta Pharmacol Sin] 2020 Jan; Vol. 41 (1), pp. 129-137. Date of Electronic Publication: 2019 Jul 24.
Typ publikacji :
Journal Article
MeSH Terms :
Acyclovir/*pharmacokinetics
Kidney/*metabolism
Leflunomide/*pharmacology
Multidrug Resistance-Associated Proteins/*antagonists & inhibitors
Organic Anion Transport Protein 1/*antagonists & inhibitors
Organic Anion Transporters, Sodium-Independent/*antagonists & inhibitors
Acyclovir/administration & dosage ; Acyclovir/metabolism ; Administration, Intravenous ; Animals ; Cells, Cultured ; Crotonates/administration & dosage ; Crotonates/metabolism ; Crotonates/pharmacology ; Dogs ; Dose-Response Relationship, Drug ; HEK293 Cells ; Humans ; Leflunomide/administration & dosage ; Leflunomide/metabolism ; Madin Darby Canine Kidney Cells/drug effects ; Madin Darby Canine Kidney Cells/metabolism ; Male ; Multidrug Resistance-Associated Proteins/metabolism ; Organic Anion Transport Protein 1/metabolism ; Organic Anion Transporters, Sodium-Independent/metabolism ; Probenecid/administration & dosage ; Probenecid/metabolism ; Probenecid/pharmacology ; Propionates/administration & dosage ; Propionates/metabolism ; Propionates/pharmacology ; Quinolines/administration & dosage ; Quinolines/metabolism ; Quinolines/pharmacology ; Rats ; Rats, Sprague-Dawley ; Tissue Distribution ; Toluidines/administration & dosage ; Toluidines/metabolism ; Toluidines/pharmacology
Czasopismo naukowe
Tytuł :
Leflunomide ameliorates experimental autoimmune myasthenia gravis by regulating humoral and cellular immune responses.
Autorzy :
Huang H; Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Sun Yat-Sen University, Guangzhou, Guangdong 510080, China.
Ran H; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, Guangdong 510080, China.
Liu X; Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Sun Yat-Sen University, Guangzhou, Guangdong 510080, China.
Yu L; Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Sun Yat-Sen University, Guangzhou, Guangdong 510080, China.
Qiu L; Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Sun Yat-Sen University, Guangzhou, Guangdong 510080, China.
Lin Z; Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Sun Yat-Sen University, Guangzhou, Guangdong 510080, China.
Ou C; Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Sun Yat-Sen University, Guangzhou, Guangdong 510080, China.
Lu Y; Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Sun Yat-Sen University, Guangzhou, Guangdong 510080, China.
Yang W; Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Sun Yat-Sen University, Guangzhou, Guangdong 510080, China.
Liu W; Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Sun Yat-Sen University, Guangzhou, Guangdong 510080, China. Electronic address: .
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Źródło :
International immunopharmacology [Int Immunopharmacol] 2021 Apr; Vol. 93, pp. 107434. Date of Electronic Publication: 2021 Feb 05.
Typ publikacji :
Journal Article
MeSH Terms :
Germinal Center/*immunology
Immunosuppressive Agents/*therapeutic use
Leflunomide/*therapeutic use
Myasthenia Gravis, Autoimmune, Experimental/*drug therapy
T-Lymphocytes, Helper-Inducer/*immunology
Adaptive Immunity/drug effects ; Animals ; Cells, Cultured ; Female ; Humans ; Immunity, Humoral/drug effects ; Interleukins/metabolism ; Rats ; Rats, Inbred Lew ; STAT3 Transcription Factor/metabolism ; Signal Transduction ; Th1-Th2 Balance/drug effects
Czasopismo naukowe
Tytuł :
Inhibition of canine distemper virus replication by blocking pyrimidine nucleotide synthesis with A77 1726, the active metabolite of the anti-inflammatory drug leflunomide.
Autorzy :
Li Y; College of Veterinary Medicine, Institute of Comparative Medicine, Yangzhou University, Yangzhou 225009, Jiangsu Province, PR China.
Yi L; State Key Laboratory for Molecular Biology of Special Economic Animals, Institute of Special Economic Animals and Plant Science, Chinese Academy of Agricultural Sciences, Changchun, PR China.
Cheng S; State Key Laboratory for Molecular Biology of Special Economic Animals, Institute of Special Economic Animals and Plant Science, Chinese Academy of Agricultural Sciences, Changchun, PR China.
Wang Y; Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Key Laboratory of Veterinary Biological Engineering and Technology, Ministry of Agriculture, National Center for Engineering Research of Veterinary Bio-products, Nanjing 210014, PR China.
Wang J; College of Veterinary Medicine, Institute of Comparative Medicine, Yangzhou University, Yangzhou 225009, Jiangsu Province, PR China.
Sun J; College of Veterinary Medicine, Institute of Comparative Medicine, Yangzhou University, Yangzhou 225009, Jiangsu Province, PR China.
Zhang Q; Institutes of Agricultural Science and Technology Development, Yangzhou University Joint International Research Laboratory of Agriculture and Agri-Product Safety of Ministry of Education of China, Yangzhou University, Yangzhou, PR China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou University, Yangzhou 225009, Jiangsu Province, PR China.; College of Veterinary Medicine, Institute of Comparative Medicine, Yangzhou University, Yangzhou 225009, Jiangsu Province, PR China.
Xu X; College of Veterinary Medicine, Institute of Comparative Medicine, Yangzhou University, Yangzhou 225009, Jiangsu Province, PR China.; Institutes of Agricultural Science and Technology Development, Yangzhou University Joint International Research Laboratory of Agriculture and Agri-Product Safety of Ministry of Education of China, Yangzhou University, Yangzhou, PR China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou University, Yangzhou 225009, Jiangsu Province, PR China.
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Źródło :
The Journal of general virology [J Gen Virol] 2021 Mar; Vol. 102 (3). Date of Electronic Publication: 2021 Jan 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiviral Agents/*pharmacology
Crotonates/*pharmacology
Distemper Virus, Canine/*drug effects
Hydroxybutyrates/*pharmacology
Nitriles/*pharmacology
Pyrimidine Nucleotides/*biosynthesis
Toluidines/*pharmacology
Animals ; Biphenyl Compounds/pharmacology ; Chlorocebus aethiops ; Crotonates/antagonists & inhibitors ; Culture Media, Conditioned ; Distemper Virus, Canine/physiology ; Hydroxybutyrates/antagonists & inhibitors ; Imidazoles/pharmacology ; Janus Kinases/antagonists & inhibitors ; Leflunomide/metabolism ; Nitriles/antagonists & inhibitors ; Nucleocapsid Proteins/metabolism ; Oxidoreductases Acting on CH-CH Group Donors/antagonists & inhibitors ; Phosphorylation ; Piperazines/pharmacology ; RNA, Small Interfering/genetics ; Ribosomal Protein S6 Kinases, 70-kDa/antagonists & inhibitors ; Ribosomal Protein S6 Kinases, 70-kDa/genetics ; Toluidines/antagonists & inhibitors ; Uridine/pharmacology ; Vero Cells ; Viral Matrix Proteins/metabolism ; Virus Replication/drug effects
Czasopismo naukowe
Tytuł :
Encapsulation of Leflunomide (LFD) in a novel niosomal formulation facilitated its delivery to THP-1 monocytic cells and enhanced Aryl hydrocarbon receptor (AhR) nuclear translocation and activation.
Autorzy :
Hasani M; Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
Sani NA; Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
Khodabakhshi B; Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Arabi MS; Medical Cellular and Molecular Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Mohammadi S; Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Iran.; Stem Cell Research Center, Golestan University of Medical Sciences, Po.Box: 4934174611, Gorgan, Iran.
Yazdani Y; Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Iran. .; Stem Cell Research Center, Golestan University of Medical Sciences, Po.Box: 4934174611, Gorgan, Iran. .
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Źródło :
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences [Daru] 2019 Dec; Vol. 27 (2), pp. 635-644. Date of Electronic Publication: 2019 Aug 20.
Typ publikacji :
Journal Article
MeSH Terms :
Basic Helix-Loop-Helix Transcription Factors/*metabolism
Leflunomide/*pharmacology
Monocytes/*metabolism
Receptors, Aryl Hydrocarbon/*metabolism
Capsules ; Cytochrome P-450 CYP1A1/genetics ; Drug Compounding ; Humans ; Interleukin-1beta/genetics ; Leflunomide/adverse effects ; Leflunomide/chemistry ; Liposomes ; Monocytes/cytology ; Monocytes/drug effects ; Protein Transport/drug effects ; Surface-Active Agents/chemistry ; THP-1 Cells
Czasopismo naukowe
Tytuł :
An in silico Workflow that Yields Experimentally Comparable Inhibitors for Human Dihydroorotate Dehydrogenase.
Autorzy :
M S; Department of Bioinformatics, Faculty of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, 603203, India.
B P; Department of Bioinformatics, Faculty of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, 603203, India.
Swaminathan P; Department of Biotechnology, Faculty of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, 603203, India.
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Źródło :
Current computer-aided drug design [Curr Comput Aided Drug Des] 2020; Vol. 16 (3), pp. 340-350.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Design*
Biphenyl Compounds/*chemistry
Enzyme Inhibitors/*chemistry
Leflunomide/*analogs & derivatives
Oxidoreductases Acting on CH-CH Group Donors/*antagonists & inhibitors
Biphenyl Compounds/pharmacology ; Computer Simulation ; Enzyme Inhibitors/pharmacology ; Humans ; Leflunomide/pharmacology ; Molecular Dynamics Simulation ; Oxidoreductases Acting on CH-CH Group Donors/metabolism ; Workflow
Czasopismo naukowe
Tytuł :
Combination of leflunomide and benazepril reduces renal injury of diabetic nephropathy rats and inhibits high-glucose induced cell apoptosis through regulation of NF-κB, TGF-β and TRPC6.
Autorzy :
Li H; Department of Nephrology, Xixi Hospital of Hangzhou (Hangzhou XIXI Affiliated Hospital of Zhejiang Chinese Medical University) , Hangzhou , Zhejiang Province , People's Republic of China.
Wang Y; Department of Nephrology, Xixi Hospital of Hangzhou (Hangzhou XIXI Affiliated Hospital of Zhejiang Chinese Medical University) , Hangzhou , Zhejiang Province , People's Republic of China.
Zhou Z; Department of Nephrology, Xixi Hospital of Hangzhou (Hangzhou XIXI Affiliated Hospital of Zhejiang Chinese Medical University) , Hangzhou , Zhejiang Province , People's Republic of China.
Tian F; Department of Nephrology, Xixi Hospital of Hangzhou (Hangzhou XIXI Affiliated Hospital of Zhejiang Chinese Medical University) , Hangzhou , Zhejiang Province , People's Republic of China.
Yang H; Department of Nephrology, Xixi Hospital of Hangzhou (Hangzhou XIXI Affiliated Hospital of Zhejiang Chinese Medical University) , Hangzhou , Zhejiang Province , People's Republic of China.
Yan J; Department of Nephrology, Xixi Hospital of Hangzhou (Hangzhou XIXI Affiliated Hospital of Zhejiang Chinese Medical University) , Hangzhou , Zhejiang Province , People's Republic of China.
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Źródło :
Renal failure [Ren Fail] 2019 Nov; Vol. 41 (1), pp. 899-906.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Benzazepines/*pharmacology
Diabetes Mellitus, Experimental/*complications
Diabetic Nephropathies/*drug therapy
Hyperglycemia/*complications
Leflunomide/*pharmacology
Animals ; Benzazepines/therapeutic use ; Blood Glucose/analysis ; Cell Line ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/chemically induced ; Diabetic Nephropathies/etiology ; Diabetic Nephropathies/pathology ; Drug Synergism ; Drug Therapy, Combination ; Glomerular Filtration Rate/drug effects ; Humans ; Hyperglycemia/blood ; Hyperglycemia/chemically induced ; Leflunomide/therapeutic use ; Male ; Mesangial Cells/drug effects ; Mesangial Cells/pathology ; NF-kappa B/metabolism ; Rats ; Rats, Sprague-Dawley ; Signal Transduction/drug effects ; Streptozocin/toxicity ; TRPC Cation Channels/metabolism ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Tytuł :
Efficacy and safety of leflunomide in IgA nephropathy: a systematic review and meta-analysis.
Autorzy :
Yi J; Department of Nephrology, The People's Hospital of Yichun City, 88 Zhongsha West Road, Yuanzhou District, Yichun, Jiangxi Province, China. .
He Z; Department of Nephrology, The People's Hospital of Yichun City, 88 Zhongsha West Road, Yuanzhou District, Yichun, Jiangxi Province, China.
Xu S; Department of Nephrology, The People's Hospital of Yichun City, 88 Zhongsha West Road, Yuanzhou District, Yichun, Jiangxi Province, China.
Feng S; Department of Nephrology, The People's Hospital of Yichun City, 88 Zhongsha West Road, Yuanzhou District, Yichun, Jiangxi Province, China.
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Źródło :
International urology and nephrology [Int Urol Nephrol] 2019 Nov; Vol. 51 (11), pp. 1987-1998. Date of Electronic Publication: 2019 Sep 12.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Glomerulonephritis, IGA/*drug therapy
Immunosuppressive Agents/*therapeutic use
Leflunomide/*therapeutic use
Humans ; Immunosuppressive Agents/adverse effects ; Leflunomide/adverse effects ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Efficacy of leflunomide in the treatment of vasculitis.
Autorzy :
Mustapha N; Vasculitis Clinic, Division of Rheumatology, Mount Sinai Hospital, University of Toronto, ON, Canada.
Barra L; Division of Rheumatology, St. Joseph's Health Care London Hospital, London, ON, Canada.
Carette S; Vasculitis Clinic, Division of Rheumatology, Mount Sinai Hospital, University of Toronto, ON, Canada.
Cuthbertson D; Department of Biostatistics, University of South Florida, Tampa, FL, USA.
Khalidi NA; Division of Rheumatology, McMaster University, Hamilton, ON, Canada.
Koening CL; Division of Rheumatology, University of Utah, Salt Lake City, UT, USA.
Langford CA; Division of Rheumatology, Cleveland Clinic, Cleveland, OH, USA.
McAlear CA; Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, USA.
Milman N; Division of Rheumatology, University of Ottawa, ON, Canada.
Moreland LW; Division of Rheumatology, University of Pittsburgh, PA, USA.
Monach PA; Division of Rheumatology, Brigham and Women's Hospital, Boston, MA, USA.
Seo P; Division of Rheumatology, Johns Hopkins University, Baltimore, MD, USA.
Specks U; Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA.
Sreih AG; Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, USA.
Ytterberg SY; Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN, USA.
Merkel PA; Division of Rheumatology and Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA USA.
Pagnoux C; Vasculitis Clinic, Division of Rheumatology, Mount Sinai Hospital, University of Toronto, ON, Canada. .
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Corporate Authors :
Canadian Vasculitis Research Network (CanVasc) and Vasculitis Clinical Research Consortium (VCRC)
Źródło :
Clinical and experimental rheumatology [Clin Exp Rheumatol] 2021 Mar-Apr; Vol. 39 Suppl 129 (2), pp. 114-118. Date of Electronic Publication: 2020 Nov 10.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis*/drug therapy
Churg-Strauss Syndrome*
Granulomatosis with Polyangiitis*
Canada ; Humans ; Leflunomide/adverse effects ; Longitudinal Studies ; Retrospective Studies
Czasopismo naukowe

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