Temat: "Lentivirus" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Lentiviruses in gene therapy clinical research.
Autorzy:: Connolly JB; Gene Therapy Advisory Committee, Department of Health, London, UK.; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2002 Dec; Vol. 9 (24), pp. 1730-4.
Typ publikacji:: Journal Article
MeSH Terms:: Genetic Vectors*
Human Experimentation*
Genetic Therapy/*ethics
Lentivirus/*genetics
Disease Transmission, Infectious ; Genetic Therapy/methods ; Germ-Line Mutation ; HIV ; Humans ; Lentivirus Infections/transmission ; Mutagenesis, Insertional ; Risk ; Virus Latency ; Virus Replication

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Skocz do pozycji: 2.

Tytuł:: CRISPR-Cas9-mediated gene knockout in primary human airway epithelial cells reveals a proinflammatory role for MUC18.
Autorzy:: Chu HW; Department of Medicine, National Jewish Health, Denver, CO, USA.
Rios C; Integrated Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.
Huang C; Department of Medicine, National Jewish Health, Denver, CO, USA.
Wesolowska-Andersen A; Integrated Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.
Burchard EG; Department of Medicine, University of California-San Francisco, San Francisco, CA, USA.; Department of Bioengineering & Therapeutic Sciences, University of California-San Francisco, San Francisco, CA, USA.
O'Connor BP; Integrated Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.
Fingerlin TE; Integrated Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.
Nichols D; Department of Pediatrics, National Jewish Health, Denver, CO, USA.
Reynolds SD; Department of Pediatrics, National Jewish Health, Denver, CO, USA.
Seibold MA; Integrated Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.; Department of Pediatrics, National Jewish Health, Denver, CO, USA.; Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado Denver, Denver, CO, USA.; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2015 Oct; Vol. 22 (10), pp. 822-9. Date of Electronic Publication: 2015 Jul 02.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Genetic Vectors*
Lentivirus*
Respiratory Mucosa/*metabolism
CD146 Antigen/genetics ; CD146 Antigen/immunology ; CD146 Antigen/metabolism ; Clustered Regularly Interspaced Short Palindromic Repeats ; Gene Expression ; Gene Knockout Techniques ; Humans ; Inflammation/genetics ; Primary Cell Culture ; Respiratory Mucosa/immunology

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Skocz do pozycji: 3.

Tytuł:: Lentivirus-mediated RASSF1A expression suppresses aggressive phenotypes of gastric cancer cells in vitro and in vivo.
Autorzy:: Zhou PH; Department of General Surgery, The First Affiliated Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Zheng JB; Department of General Surgery, The First Affiliated Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Wei GB; Department of General Surgery, The First Affiliated Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Wang XL; Department of General Surgery, The First Affiliated Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Wang W; Department of General Surgery, The First Affiliated Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Chen NZ; Department of General Surgery, The First Affiliated Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Yu JH; Department of General Surgery, The First Affiliated Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Yao JF; Department of General Surgery, The First Affiliated Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Wang H; Department of General Surgery, The First Affiliated Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Lu SY; Department of General Surgery, The First Affiliated Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Sun XJ; Department of General Surgery, The First Affiliated Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, China.; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2015 Oct; Vol. 22 (10), pp. 793-801. Date of Electronic Publication: 2015 May 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Therapy*
Genetic Vectors*
Lentivirus*
Stomach Neoplasms/*genetics
Tumor Suppressor Proteins/*genetics
Animals ; Cell Line, Tumor ; Cell Proliferation/genetics ; Cell Survival/genetics ; Gene Expression Regulation, Neoplastic ; Heterografts ; Humans ; Mice ; Mice, Nude ; Stomach Neoplasms/pathology ; Stomach Neoplasms/therapy ; Tumor Suppressor Proteins/biosynthesis

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Skocz do pozycji: 4.

Tytuł:: Gene transfer engineering for astrocyte-specific silencing in the CNS.
Autorzy:: Merienne N; Laboratory of Cellular and Molecular Neurotherapies (LCMN), Department of Clinical Neurosciences (DNC), Lausanne University Hospital (CHUV), Lausanne, Switzerland.; LCMN, Neuroscience Research Center (CRN), Lausanne University Hospital, Lausanne, Switzerland.
Delzor A; Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Institute of Biomedical Imaging (I2BM), Molecular Imaging Research Center (MIRCen), Fontenay-aux-Roses, France.; CNRS-CEA URA2210, Fontenay-aux-Roses, France.
Viret A; Laboratory of Cellular and Molecular Neurotherapies (LCMN), Department of Clinical Neurosciences (DNC), Lausanne University Hospital (CHUV), Lausanne, Switzerland.; LCMN, Neuroscience Research Center (CRN), Lausanne University Hospital, Lausanne, Switzerland.
Dufour N; Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Institute of Biomedical Imaging (I2BM), Molecular Imaging Research Center (MIRCen), Fontenay-aux-Roses, France.; CNRS-CEA URA2210, Fontenay-aux-Roses, France.
Rey M; Laboratory of Cellular and Molecular Neurotherapies (LCMN), Department of Clinical Neurosciences (DNC), Lausanne University Hospital (CHUV), Lausanne, Switzerland.; LCMN, Neuroscience Research Center (CRN), Lausanne University Hospital, Lausanne, Switzerland.
Hantraye P; Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Institute of Biomedical Imaging (I2BM), Molecular Imaging Research Center (MIRCen), Fontenay-aux-Roses, France.; CNRS-CEA URA2210, Fontenay-aux-Roses, France.
Déglon N; Laboratory of Cellular and Molecular Neurotherapies (LCMN), Department of Clinical Neurosciences (DNC), Lausanne University Hospital (CHUV), Lausanne, Switzerland.; LCMN, Neuroscience Research Center (CRN), Lausanne University Hospital, Lausanne, Switzerland.; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2015 Oct; Vol. 22 (10), pp. 830-9. Date of Electronic Publication: 2015 Jun 05.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Transfer Techniques*
Genetic Vectors*
Lentivirus*
RNA, Small Interfering*
Astrocytes/*physiology
Animals ; Central Nervous System/cytology ; Central Nervous System/physiology ; Gene Expression Regulation ; Gene Silencing ; Mice ; Mice, Transgenic ; Tetracycline

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Skocz do pozycji: 5.

Tytuł:: Gene delivery to rat and human Schwann cells and nerve segments: a comparison of AAV 1-9 and lentiviral vectors.
Autorzy:: Hoyng SA; Department of Neuroregeneration, Netherlands Insititute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.; Department of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands.
De Winter F; Department of Neuroregeneration, Netherlands Insititute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.; Department of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands.
Gnavi S; Department of Neuroregeneration, Netherlands Insititute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.; Neuroscience Institute of the Cavalieri Ottolenghi Foundation and Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.
van Egmond L; Department of Neuroregeneration, Netherlands Insititute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.
Attwell CL; Department of Neuroregeneration, Netherlands Insititute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.
Tannemaat MR; Department of Neuroregeneration, Netherlands Insititute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Verhaagen J; Department of Neuroregeneration, Netherlands Insititute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.; Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Malessy MJ; Department of Neuroregeneration, Netherlands Insititute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.; Department of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands.; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2015 Oct; Vol. 22 (10), pp. 767-80. Date of Electronic Publication: 2015 May 04.
Typ publikacji:: Journal Article
MeSH Terms:: Dependovirus*
Genetic Therapy*
Genetic Vectors*
Lentivirus*
Schwann Cells/*physiology
Transduction, Genetic/*methods
Animals ; Cells, Cultured ; Humans ; Peripheral Nerve Injuries/therapy ; Rats ; Schwann Cells/transplantation

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Skocz do pozycji: 6.

Tytuł:: Lentivirus-induced 'Smart' dendritic cells: Pharmacodynamics and GMP-compliant production for immunotherapy against TRP2-positive melanoma.
Autorzy:: Sundarasetty BS; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
Chan L; Department of Hematological Medicine, Cell and Gene Therapy at King's, The Rayne Institute, King's College London, London, UK.
Darling D; Department of Hematological Medicine, Cell and Gene Therapy at King's, The Rayne Institute, King's College London, London, UK.
Giunti G; Department of Hematological Medicine, Cell and Gene Therapy at King's, The Rayne Institute, King's College London, London, UK.
Farzaneh F; Department of Hematological Medicine, Cell and Gene Therapy at King's, The Rayne Institute, King's College London, London, UK.
Schenck F; Department of Dermatology and Allergy, Skin Cancer Center Hannover, Hannover Medical School, Hannover, Germany.
Naundorf S; EUFETS GmbH, Idar-Oberstein, Heidelberg, Germany.
Kuehlcke K; EUFETS GmbH, Idar-Oberstein, Heidelberg, Germany.
Ruggiero E; Division of Translational Oncology, National Center for Tumor Diseases, Heidelberg, Germany.
Schmidt M; Division of Translational Oncology, National Center for Tumor Diseases, Heidelberg, Germany.
von Kalle C; Division of Translational Oncology, National Center for Tumor Diseases, Heidelberg, Germany.
Rothe M; Department of Experimental Hematology, Hannover, Germany.
Hoon DS; John Wayne Cancer Institute, Santa Monica, CA, USA.
Gerasch L; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
Figueiredo C; Department of Transfusion Medicine, Hannover Medical School, Hannover, Germany.
Koehl U; Institute for Cell Therapeutics and GMP core facility IFB-Tx, Hannover Medical School, Hannover, Germany.
Blasczyk R; Department of Transfusion Medicine, Hannover Medical School, Hannover, Germany.
Gutzmer R; Department of Dermatology and Allergy, Skin Cancer Center Hannover, Hannover Medical School, Hannover, Germany.
Stripecke R; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2015 Sep; Vol. 22 (9), pp. 707-20. Date of Electronic Publication: 2015 May 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cancer Vaccines/*therapeutic use
Dendritic Cells/*immunology
Lentivirus/*metabolism
Melanoma/*therapy
Membrane Proteins/*metabolism
Peptide Fragments/*metabolism
Cancer Vaccines/genetics ; Cancer Vaccines/immunology ; Genetic Vectors ; HEK293 Cells ; Humans ; Immunotherapy/methods ; Lentivirus/genetics ; Melanoma/immunology ; T-Lymphocytes, Cytotoxic/immunology

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Skocz do pozycji: 7.

Tytuł:: Shedding of clinical-grade lentiviral vectors is not detected in a gene therapy setting.
Autorzy:: Cesani M; Division of Regenerative Medicine and Stem Cells, San Raffaele Scientific Institute, San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Milan, Italy.
Plati T; Division of Regenerative Medicine and Stem Cells, San Raffaele Scientific Institute, San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Milan, Italy.
Lorioli L; 1] Division of Regenerative Medicine and Stem Cells, San Raffaele Scientific Institute, San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Milan, Italy [2] Vita-Salute San Raffaele University, Milan, Italy.
Benedicenti F; Division of Regenerative Medicine and Stem Cells, San Raffaele Scientific Institute, San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Milan, Italy.
Redaelli D; Division of Regenerative Medicine and Stem Cells, San Raffaele Scientific Institute, San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Milan, Italy.
Dionisio F; Division of Regenerative Medicine and Stem Cells, San Raffaele Scientific Institute, San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Milan, Italy.
Biasco L; Division of Regenerative Medicine and Stem Cells, San Raffaele Scientific Institute, San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Milan, Italy.
Montini E; Division of Regenerative Medicine and Stem Cells, San Raffaele Scientific Institute, San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Milan, Italy.
Naldini L; 1] Division of Regenerative Medicine and Stem Cells, San Raffaele Scientific Institute, San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Milan, Italy [2] Vita-Salute San Raffaele University, Milan, Italy.
Biffi A; Division of Regenerative Medicine and Stem Cells, San Raffaele Scientific Institute, San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Milan, Italy.; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2015 Jun; Vol. 22 (6), pp. 496-502. Date of Electronic Publication: 2015 Mar 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Therapy*
Genetic Vectors*
Virus Shedding*
Lentivirus/*genetics
Antigens, CD34/metabolism ; Humans ; Lentivirus/physiology ; Stem Cells/metabolism

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Skocz do pozycji: 8.

Tytuł:: Retinal transduction profiles by high-capacity viral vectors.
Autorzy:: Puppo A; Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy.
Cesi G; Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy.
Marrocco E; Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy.
Piccolo P; Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy.
Jacca S; Department of Medical Veterinary Science, University of Parma, Parma, Italy.
Shayakhmetov DM; Lowance Center for Human Immunology, Departments of Pediatrics and Medicine, Emory University, Atlanta, GA, USA.
Parks RJ; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Davidson BL; Departments of Internal Medicine, Neurology and Molecular Physiology & Biophysics, University of Iowa, Iowa City, IA, USA.
Colloca S; Okairos, Rome, Italy.
Brunetti-Pierri N; Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy.
Ng P; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Donofrio G; Department of Medical Veterinary Science, University of Parma, Parma, Italy.
Auricchio A; 1] Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy [2] Medical Genetics, Department of Translational Medicine, University of Naples Federico II, Naples, Italy.; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2014 Oct; Vol. 21 (10), pp. 855-65. Date of Electronic Publication: 2014 Jul 03.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Dependovirus/*genetics
Herpesvirus 4, Bovine/*genetics
Lentivirus/*genetics
Retinal Pigment Epithelium/*virology
Animals ; Dependovirus/classification ; Electroretinography ; Epithelial Cells/virology ; Genetic Vectors/administration & dosage ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Herpesvirus 4, Bovine/classification ; Lentivirus/classification ; Male ; Mice ; Mice, Inbred BALB C ; Photoreceptor Cells, Vertebrate/metabolism ; Retinal Pigment Epithelium/cytology ; Transduction, Genetic

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Skocz do pozycji: 9.

Tytuł:: Injection parameters and virus dependent choice of promoters to improve neuron targeting in the nonhuman primate brain.
Autorzy:: Lerchner W; Laboratory of Neuropsychology, National Institute of Mental Health/NIMH/DHHS, Bethesda, MD, USA.
Corgiat B; Laboratory of Neuropsychology, National Institute of Mental Health/NIMH/DHHS, Bethesda, MD, USA.
Der Minassian V; Laboratory of Neuropsychology, National Institute of Mental Health/NIMH/DHHS, Bethesda, MD, USA.
Saunders RC; Laboratory of Neuropsychology, National Institute of Mental Health/NIMH/DHHS, Bethesda, MD, USA.
Richmond BJ; Laboratory of Neuropsychology, National Institute of Mental Health/NIMH/DHHS, Bethesda, MD, USA.; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2014 Mar; Vol. 21 (3), pp. 233-41. Date of Electronic Publication: 2014 Jan 09.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Promoter Regions, Genetic*
Brain/*metabolism
Dependovirus/*genetics
Genetic Vectors/*administration & dosage
Lentivirus/*genetics
Neurons/*metabolism
Animals ; Brain/cytology ; Cytomegalovirus/genetics ; Dependovirus/metabolism ; Genetic Vectors/genetics ; Injections, Intraventricular ; Lentivirus/metabolism ; Macaca fascicularis ; Neuroglia/metabolism ; Organ Specificity ; Synapsins/genetics ; Transduction, Genetic/methods ; Tyrosine 3-Monooxygenase/genetics ; Tyrosine 3-Monooxygenase/metabolism

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Skocz do pozycji: 10.

Tytuł:: Restoring ciliary function to differentiated primary ciliary dyskinesia cells with a lentiviral vector.
Autorzy:: Ostrowski LE; Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center, University of North Carolina, Chapel Hill, NC, USA.
Yin W; Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center, University of North Carolina, Chapel Hill, NC, USA.
Patel M; Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center, University of North Carolina, Chapel Hill, NC, USA.
Sechelski J; Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center, University of North Carolina, Chapel Hill, NC, USA.
Rogers T; Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center, University of North Carolina, Chapel Hill, NC, USA.
Burns K; Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center, University of North Carolina, Chapel Hill, NC, USA.
Grubb BR; Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center, University of North Carolina, Chapel Hill, NC, USA.
Olsen JC; Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center, University of North Carolina, Chapel Hill, NC, USA.; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2014 Mar; Vol. 21 (3), pp. 253-61. Date of Electronic Publication: 2014 Jan 23.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Therapy*
Axonemal Dyneins/*metabolism
Ciliary Motility Disorders/*therapy
Lentivirus/*genetics
Animals ; Axonemal Dyneins/genetics ; Cells, Cultured ; Cilia/metabolism ; Cilia/physiology ; Estrogen Antagonists/pharmacology ; Genetic Vectors/genetics ; Integrases/genetics ; Lentivirus/metabolism ; Mice ; Mice, Inbred C57BL ; Respiratory Mucosa/drug effects ; Respiratory Mucosa/metabolism ; Rhinitis/therapy ; Sinusitis/therapy ; Tamoxifen/pharmacology

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Skocz do pozycji: 11.

Tytuł:: Characterization of a third generation lentiviral vector pseudotyped with Nipah virus envelope proteins for endothelial cell transduction.
Autorzy:: Witting SR; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.
Vallanda P
Gamble AL; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2013 Oct; Vol. 20 (10), pp. 997-1005. Date of Electronic Publication: 2013 May 23.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Genetic Vectors*
Endothelial Cells/*metabolism
Genetic Therapy/*methods
Lentivirus/*genetics
Nipah Virus/*genetics
Transduction, Genetic/*methods
Viral Envelope Proteins/*genetics
Animals ; Cells, Cultured ; HEK293 Cells ; Human Umbilical Vein Endothelial Cells ; Humans ; Lentivirus/classification ; Mice ; Molecular Typing ; Nipah Virus/metabolism ; Viral Envelope Proteins/metabolism

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Skocz do pozycji: 12.

Tytuł:: Understanding lentiviral vector chromatin targeting: working to reduce insertional mutagenic potential for gene therapy.
Autorzy:: Papayannakos C; Division of Infectious Diseases-Center for Human Virology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Daniel R; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2013 Jun; Vol. 20 (6), pp. 581-8. Date of Electronic Publication: 2012 Nov 22.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms:: Genetic Therapy*
Adaptor Proteins, Signal Transducing/*genetics
Chromatin/*genetics
Lentivirus/*genetics
Mutagenesis, Insertional/*genetics
Transcription Factors/*genetics
Clinical Trials as Topic ; Gene Transfer Techniques ; Genetic Vectors ; Humans ; Lentivirus/growth & development ; Virus Integration/genetics ; Virus Replication/genetics

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Skocz do pozycji: 13.

Tytuł:: Ocular gene delivery using lentiviral vectors.
Autorzy:: Balaggan KS; Department of Genetics, Institute of Ophthalmology, London, UK. />Ali RR; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2012 Feb; Vol. 19 (2), pp. 145-53. Date of Electronic Publication: 2011 Nov 03.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Gene Transfer Techniques*
Lentivirus*
Choroidal Neovascularization/*genetics
Glaucoma/*genetics
Retinal Degeneration/*genetics
Animals ; Choroidal Neovascularization/therapy ; Disease Models, Animal ; Gene Expression ; Genetic Therapy ; Genetic Vectors/administration & dosage ; Glaucoma/therapy ; Humans ; Retinal Degeneration/therapy

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Skocz do pozycji: 14.

Tytuł:: Corticospinal tract transduction: a comparison of seven adeno-associated viral vector serotypes and a non-integrating lentiviral vector.
Autorzy:: Hutson TH; Neurorestoration Group, Wolfson Centre for Age-Related Diseases, King's College London, London, UK. />Verhaagen J
Yáñez-Muñoz RJ
Moon LD; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2012 Jan; Vol. 19 (1), pp. 49-60. Date of Electronic Publication: 2011 May 12.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Dependovirus/*metabolism
Genetic Vectors/*metabolism
Lentivirus/*metabolism
Pyramidal Tracts/*metabolism
Animals ; Astrocytes/cytology ; Astrocytes/metabolism ; Cell Count ; Dependovirus/classification ; Dependovirus/genetics ; Gene Transfer Techniques ; Genetic Therapy ; Genetic Vectors/genetics ; Green Fluorescent Proteins/metabolism ; HEK293 Cells ; Humans ; Lentivirus/genetics ; Microglia/cytology ; Microglia/metabolism ; Neurons/cytology ; Neurons/metabolism ; Pyramidal Tracts/cytology ; Rats ; Rats, Sprague-Dawley ; Serotyping ; Transfection/methods ; Virus Integration

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Skocz do pozycji: 15.

Tytuł:: Differential immune responses mediated by adenovirus- and lentivirus-transduced DCs in a HER-2/neu overexpressing tumor model.
Autorzy:: Felizardo TC; Campbell Family Cancer Research Institute and Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada.
Wang JC
McGray RA
Evelegh C
Spaner DE
Fowler DH
Bramson JL
Medin JA; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2011 Oct; Vol. 18 (10), pp. 986-95. Date of Electronic Publication: 2011 Apr 14.
Typ publikacji:: Comparative Study; Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adenoviridae*
Lentivirus*
Dendritic Cells/*transplantation
Genes, erbB-2/*genetics
Genetic Vectors/*administration & dosage
Immunotherapy/*methods
Neoplasms/*therapy
Adoptive Transfer ; Animals ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Interferon-gamma/metabolism ; Mice ; Neoplasms/immunology ; Rats

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Skocz do pozycji: 16.

Tytuł:: Development of a nonintegrating Rev-dependent lentiviral vector carrying diphtheria toxin A chain and human TRAF6 to target HIV reservoirs.
Autorzy:: Wang Z; Transplantation Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Harvard University, Boston, MA, USA.
Tang Z
Zheng Y
Yu D
Spear M
Iyer SR
Bishop B
Wu Y; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2010 Sep; Vol. 17 (9), pp. 1063-76. Date of Electronic Publication: 2010 Apr 22.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Diphtheria Toxin/*genetics
Gene Products, rev/*genetics
Genetic Vectors/*genetics
HIV-1/*physiology
Lentivirus/*genetics
Peptide Fragments/*genetics
TNF Receptor-Associated Factor 6/*genetics
Apoptosis ; Cell Death ; Cell Line ; DNA, Viral/metabolism ; Diphtheria Toxin/metabolism ; Fluoroimmunoassay ; Genetic Therapy/methods ; Genetic Vectors/metabolism ; HIV Infections/genetics ; HIV-1/genetics ; Humans ; Lentivirus/metabolism ; Peptide Fragments/metabolism ; TNF Receptor-Associated Factor 6/metabolism ; Virus Replication/physiology

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Skocz do pozycji: 17.

Tytuł:: A dual promoter lentiviral vector for the in vivo evaluation of gene therapeutic approaches to axon regeneration after spinal cord injury.
Autorzy:: Löw K; Department of Neurosciences, University of California-San Diego, La Jolla, CA, USA. />Blesch A
Herrmann J
Tuszynski MH; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2010 May; Vol. 17 (5), pp. 577-91. Date of Electronic Publication: 2010 Mar 04.
Typ publikacji:: Journal Article
MeSH Terms:: Genetic Vectors*
Lentivirus*
Nerve Regeneration*
Axons/*physiology
Genetic Therapy/*methods
Spinal Cord Injuries/*therapy
Actins/genetics ; Animals ; Female ; Mice ; Peptide Elongation Factor 1/genetics ; Promoter Regions, Genetic ; Rats

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Skocz do pozycji: 18.

Tytuł:: Lentiviral vectors incorporating a human elongation factor 1alpha promoter for the treatment of canine leukocyte adhesion deficiency.
Autorzy:: Nelson EJ; Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1203, USA.
Tuschong LM
Hunter MJ
Bauer TR Jr
Burkholder TH
Hickstein DD; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2010 May; Vol. 17 (5), pp. 672-7. Date of Electronic Publication: 2010 Feb 18.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:: Genetic Vectors*
Lentivirus*
Promoter Regions, Genetic*
CD18 Antigens/*genetics
Genetic Therapy/*methods
Leukocyte-Adhesion Deficiency Syndrome/*therapy
Peptide Elongation Factor 1/*genetics
Animals ; Antigens, CD34/genetics ; Bone Marrow/immunology ; Bone Marrow Transplantation ; Disease Models, Animal ; Dogs ; Humans ; Leukocyte-Adhesion Deficiency Syndrome/genetics ; Leukocyte-Adhesion Deficiency Syndrome/veterinary ; Neutrophils/immunology ; Transduction, Genetic

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Skocz do pozycji: 19.

Tytuł:: High-titer lentiviral vectors stimulate fetal calf serum-specific human CD4 T-cell responses: implications in human gene therapy.
Autorzy:: Bao L; Department of Pediatrics, Division of Blood and Marrow Transplantation, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Guo H
Huang X
Tammana S
Wong M
McIvor RS
Zhou X; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2009 Jun; Vol. 16 (6), pp. 788-95. Date of Electronic Publication: 2009 Apr 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: CD4-Positive T-Lymphocytes/*immunology
Cell Culture Techniques/*methods
Dendritic Cells/*immunology
Epitopes, T-Lymphocyte/*immunology
Genetic Vectors/*immunology
Lentivirus/*immunology
Animals ; Antigen Presentation/immunology ; Cattle ; Cell Line ; Culture Media ; Gene Transfer Techniques ; Genes, MHC Class II ; Genetic Therapy ; Genetic Vectors/genetics ; HLA Antigens ; Hemagglutinin Glycoproteins, Influenza Virus/immunology ; Humans ; Lentivirus/genetics ; Plasmids ; Transduction, Genetic/methods

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Skocz do pozycji: 20.

Tytuł:: Efficient gene delivery to the adult and fetal CNS using pseudotyped non-integrating lentiviral vectors.
Autorzy:: Rahim AA; Perinatal Brain Protection and Repair Group, Department of Obstetrics and Gynaecology, University College London, London, UK.
Wong AM
Howe SJ
Buckley SM
Acosta-Saltos AD
Elston KE
Ward NJ
Philpott NJ
Cooper JD
Anderson PN
Waddington SN
Thrasher AJ
Raivich G; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2009 Apr; Vol. 16 (4), pp. 509-20. Date of Electronic Publication: 2009 Jan 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Transfer Techniques*
Brain/*metabolism
Genetic Vectors/*administration & dosage
Lentivirus/*genetics
Animals ; Corpus Striatum/metabolism ; Fetal Therapies/methods ; Genetic Therapy/methods ; Lentivirus/physiology ; Mice ; Rats ; Spinal Cord/metabolism ; Stereotaxic Techniques ; Transduction, Genetic ; Virus Integration

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