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Tytuł :
A dose-finding and pharmacodynamic study of bortezomib in combination with weekly paclitaxel in patients with advanced solid tumors.
Autorzy :
Ramaswamy B
Bekaii-Saab T
Schaaf LJ
Lesinski GB
Lucas DM
Young DC
Ruppert AS
Byrd JC
Culler K
Wilkins D
Wright JJ
Grever MR
Shapiro CL
Ramaswamy, Bhuvaneswari
Bekaii-Saab, Tanios
Schaaf, Larry J
Lesinski, Gregory B
Lucas, David M
Young, Donn C
Ruppert, Amy S
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Źródło :
Cancer Chemotherapy & Pharmacology; 2010 May, Vol. 66 Issue 1, p151-158, 8p
Czasopismo naukowe
Tytuł :
Pepinemab (Anti-SEMA4D) in Combination with Ipilimumab or Nivolumab for Patients with Resectable Pancreatic and Colorectal Cancer.
Autorzy :
Rossi AJ; Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Khan TM; Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Hong H; Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Lesinski GB; Emory University School of Medicine, Winship Cancer Institute, Atlanta, GA, USA.
Wu C; Emory University School of Medicine, Winship Cancer Institute, Atlanta, GA, USA. .
Hernandez JM; Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. .
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Źródło :
Annals of surgical oncology [Ann Surg Oncol] 2021 May 13. Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Letter
Opinia redakcyjna
Tytuł :
Mismatch Repair (MMR) Gene Alteration and BRAF V600E Mutation Are Potential Predictive Biomarkers of Immune Checkpoint Inhibitors in MMR-Deficient Colorectal Cancer.
Autorzy :
Sahin IH; H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.
Goyal S; Emory University School of Medicine, Winship Cancer Institute, Atlanta, Georgia, USA.
Pumpalova Y; Stanford University Cancer Institute, Stanford, California, USA.
Sonbol MB; Mayo Clinic, Rochester, Minnesota, USA.
Das S; Vanderbilt University Ingram Cancer Center, Nashville, Tennessee, USA.
Haraldsdottir S; Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Ahn D; Mayo Clinic, Rochester, Minnesota, USA.
Ciombor KK; Vanderbilt University Ingram Cancer Center, Nashville, Tennessee, USA.
Chen Z; Emory University School of Medicine, Winship Cancer Institute, Atlanta, Georgia, USA.
Draper A; Emory University School of Medicine, Winship Cancer Institute, Atlanta, Georgia, USA.
Berlin J; Vanderbilt University Ingram Cancer Center, Nashville, Tennessee, USA.
Bekaii-Saab T; Mayo Clinic, Rochester, Minnesota, USA.
Lesinski GB; Emory University School of Medicine, Winship Cancer Institute, Atlanta, Georgia, USA.
El-Rayes BF; Emory University School of Medicine, Winship Cancer Institute, Atlanta, Georgia, USA.
Wu C; Emory University School of Medicine, Winship Cancer Institute, Atlanta, Georgia, USA.
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Źródło :
The oncologist [Oncologist] 2021 Feb 25. Date of Electronic Publication: 2021 Feb 25.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Heat Shock Protein-90 Inhibition Alters Activation of Pancreatic Stellate Cells and Enhances the Efficacy of PD-1 Blockade in Pancreatic Cancer.
Autorzy :
Zhang Y; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.; Department of Oncology, the First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi, China.
Ware MB; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Zaidi MY; Department of Surgery, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Ruggieri AN; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Olson BM; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Komar H; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Farren MR; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Nagaraju GP; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Zhang C; Department of Biostatistics, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Chen Z; Division of Epidemiology and Biostatistics, University of Illinois at Chicago, Chicago, Illinois.
Sarmiento JM; Department of Surgery, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Ahmed R; Emory Vaccine Center, Atlanta, Georgia.
Maithel SK; Department of Surgery, Winship Cancer Institute of Emory University, Atlanta, Georgia.
El-Rayes BF; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia. gregory.b.lesinski@emory.edu .
Lesinski GB; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia. gregory.b.lesinski@emory.edu .
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Źródło :
Molecular cancer therapeutics [Mol Cancer Ther] 2021 Jan; Vol. 20 (1), pp. 150-160. Date of Electronic Publication: 2020 Oct 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
Czasopismo naukowe
Tytuł :
Delayed Processing of Secretin-Induced Pancreas Fluid Influences the Quality and Integrity of Proteins and Nucleic Acids.
Autorzy :
Cruz-Monserrate Z
Gumpper K
Kaul S
Badi N
Terhorst S
Dubay K
Lesinski GB; Winship Cancer Institute, Department of Hematology and Medical Oncology, Emory University, Atlanta, GA.
Fisher W
McElhany A
Lara LF; From the Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine.
Krishna S; From the Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine.
Mace T
Higuita-Castro N
Ortega-Pineda L; Department of Biomedical Engineering.
Freitas MA
Hinton A; Division of Biostatistics, College of Public Health, The Ohio State University, Columbus, OH.
Yadav D; Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh, Pittsburgh, PA.
Hart PA; From the Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine.
Pandol SJ; Digestive Disease Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Ahmed S; Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA.
Fatou B; Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA.
Steen H; Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA.
Conwell DL; From the Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine.
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Corporate Authors :
Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer##
Źródło :
Pancreas [Pancreas] 2021 Jan 01; Vol. 50 (1), pp. 17-28.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Braking the cell's cycle and invigorating T-cell immunity against pancreatic cancer.
Autorzy :
Lesinski GB; Hematology and Medical Oncolgy, Emory University, Atlanta, Georgia, USA gregory.b.lesinski@emory.edu.
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Źródło :
Gut [Gut] 2021 Jan; Vol. 70 (1), pp. 4-5. Date of Electronic Publication: 2020 Jun 22.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Suppressive myeloid cells are expanded by biliary tract cancer-derived cytokines in vitro and associate with aggressive disease.
Autorzy :
Ware MB; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.
Zaidi MY; Department of Surgery, Winship Cancer Institute of Emory University, Atlanta, GA, USA.
Yang J; Divisions of Medical Oncology and Gastroenterology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
Turgeon MK; Department of Surgery, Winship Cancer Institute of Emory University, Atlanta, GA, USA.
Krasinskas A; Department of Pathology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.
Mace TA; Divisions of Medical Oncology and Gastroenterology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
Keenan K; Divisions of Medical Oncology and Gastroenterology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
Farren MR; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.
Ruggieri AN; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.
Li Y; Biostatistics and Bioinformatics, Winship Cancer Institute of Emory University, Atlanta, GA, USA.
Zhang C; Biostatistics and Bioinformatics, Winship Cancer Institute of Emory University, Atlanta, GA, USA.
Chen Z; Biostatistics and Bioinformatics, Winship Cancer Institute of Emory University, Atlanta, GA, USA.
Young GS; Center for Biostatistics, The Ohio State University, Columbus, OH, USA.
Elnaggar O; Divisions of Medical Oncology and Gastroenterology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
Che Z; Divisions of Medical Oncology and Gastroenterology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
Maithel SK; Department of Surgery, Winship Cancer Institute of Emory University, Atlanta, GA, USA.
Bekaii-Saab T; Mayo Clinic Cancer Center, Mayo Clinic, Phoenix, AZ, USA.
El-Rayes B; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.
Lesinski GB; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA. gregory.b.lesinski@emory.edu.
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Źródło :
British journal of cancer [Br J Cancer] 2020 Oct; Vol. 123 (9), pp. 1377-1386. Date of Electronic Publication: 2020 Aug 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Biliary Tract Neoplasms/*metabolism
Biliary Tract Neoplasms/*pathology
Cell Proliferation/*drug effects
Cytokines/*pharmacology
Myeloid-Derived Suppressor Cells/*drug effects
Calgranulin B/metabolism ; Cell Count ; Cells, Cultured ; Culture Media, Conditioned/metabolism ; Culture Media, Conditioned/pharmacology ; Cytokines/metabolism ; Humans ; Lymphocyte Activation/drug effects ; Myeloid Cells/drug effects ; Myeloid Cells/pathology ; Myeloid Cells/physiology ; Myeloid-Derived Suppressor Cells/pathology ; Myeloid-Derived Suppressor Cells/physiology ; Neoplasm Grading ; Neoplasm Invasiveness ; Sialic Acid Binding Ig-like Lectin 3/metabolism
Czasopismo naukowe
Tytuł :
IL6 Fuels Durable Memory for Th17 Cell-Mediated Responses to Tumors.
Autorzy :
Knochelmann HM; Department of Microbiology & Immunology, Medical University of South Carolina, Charleston, South Carolina. .; Department of Dermatology & Dermatologic Surgery, Medical University of South Carolina, Charleston, South Carolina.
Dwyer CJ; Department of Microbiology & Immunology, Medical University of South Carolina, Charleston, South Carolina.; Department of Dermatology & Dermatologic Surgery, Medical University of South Carolina, Charleston, South Carolina.
Smith AS; Department of Microbiology & Immunology, Medical University of South Carolina, Charleston, South Carolina.; Department of Dermatology & Dermatologic Surgery, Medical University of South Carolina, Charleston, South Carolina.
Bowers JS; Department of Microbiology & Immunology, Medical University of South Carolina, Charleston, South Carolina.; Department of Dermatology & Dermatologic Surgery, Medical University of South Carolina, Charleston, South Carolina.
Wyatt MM; Department of Microbiology & Immunology, Medical University of South Carolina, Charleston, South Carolina.; Department of Dermatology & Dermatologic Surgery, Medical University of South Carolina, Charleston, South Carolina.
Nelson MH; Department of Microbiology & Immunology, Medical University of South Carolina, Charleston, South Carolina.; Department of Dermatology & Dermatologic Surgery, Medical University of South Carolina, Charleston, South Carolina.
Rangel Rivera GO; Department of Microbiology & Immunology, Medical University of South Carolina, Charleston, South Carolina.; Department of Dermatology & Dermatologic Surgery, Medical University of South Carolina, Charleston, South Carolina.
Horton JD; Department of Microbiology & Immunology, Medical University of South Carolina, Charleston, South Carolina.
Krieg C; Department of Microbiology & Immunology, Medical University of South Carolina, Charleston, South Carolina.
Armeson K; Department of Public Health Sciences, Medical University of South Carolina, Charleston, South Carolina.
Lesinski GB; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Rubinstein MP; Department of Microbiology & Immunology, Medical University of South Carolina, Charleston, South Carolina.; Department of Surgery, Medical University of South Carolina, Charleston, South Carolina.
Li Z; Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, Ohio.
Paulos CM; Department of Microbiology & Immunology, Medical University of South Carolina, Charleston, South Carolina. .; Department of Dermatology & Dermatologic Surgery, Medical University of South Carolina, Charleston, South Carolina.
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Źródło :
Cancer research [Cancer Res] 2020 Sep 15; Vol. 80 (18), pp. 3920-3932. Date of Electronic Publication: 2020 Jun 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Neoplasms*/therapy
Th17 Cells*
Cell- and Tissue-Based Therapy ; Cytokines ; Humans ; Interleukin-6
Czasopismo naukowe
Tytuł :
Mirage or long-awaited oasis: reinvigorating T-cell responses in pancreatic cancer.
Autorzy :
Ware MB; Hematology and Oncology, Emory University Winship Cancer Institute, Atlanta, Georgia, USA.
El-Rayes BF; Hematology and Oncology, Emory University Winship Cancer Institute, Atlanta, Georgia, USA.
Lesinski GB; Hematology and Oncology, Emory University Winship Cancer Institute, Atlanta, Georgia, USA gregory.b.lesinski@emory.edu.
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Źródło :
Journal for immunotherapy of cancer [J Immunother Cancer] 2020 Aug; Vol. 8 (2).
Typ publikacji :
Journal Article; Review; Research Support, N.I.H., Extramural
Czasopismo naukowe
Tytuł :
Napabucasin (BBI 608), a potent chemoradiosensitizer in rectal cancer.
Autorzy :
Nagaraju GP; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
Farran B; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
Farren M; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
Chalikonda G; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
Wu C; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
Lesinski GB; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
El-Rayes BF; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
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Źródło :
Cancer [Cancer] 2020 Jul 15; Vol. 126 (14), pp. 3360-3371. Date of Electronic Publication: 2020 May 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Czasopismo naukowe
Tytuł :
Optical Control of Cytokine Signaling via Bioinspired, Polymer-Induced Latency.
Autorzy :
Perdue LA; Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332-0002, United States.
Do P; Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332-0002, United States.
David C; Department of Pediatrics, Emory School of Medicine, Atlanta, Georgia 30322, United States.; Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta, Atlanta, Georgia 30322, United States.; Winship Cancer Institute of Emory University, Atlanta, Georgia 30322, United States.
Chyong A; Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332-0002, United States.
Kellner AV; Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332-0002, United States.
Ruggieri A; Department of Hematology and Medical Oncology, Emory School of Medicine, Atlanta, Georgia 30322, United States.; Winship Cancer Institute of Emory University, Atlanta, Georgia 30322, United States.
Kim HR; Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332-0002, United States.
Salaita K; Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332-0002, United States.; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States.
Lesinski GB; Department of Hematology and Medical Oncology, Emory School of Medicine, Atlanta, Georgia 30322, United States.; Winship Cancer Institute of Emory University, Atlanta, Georgia 30322, United States.
Porter CC; Department of Pediatrics, Emory School of Medicine, Atlanta, Georgia 30322, United States.; Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta, Atlanta, Georgia 30322, United States.; Winship Cancer Institute of Emory University, Atlanta, Georgia 30322, United States.
Dreaden EC; Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332-0002, United States.; Department of Pediatrics, Emory School of Medicine, Atlanta, Georgia 30322, United States.; Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta, Atlanta, Georgia 30322, United States.; Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia 30332-0002, United States.; Winship Cancer Institute of Emory University, Atlanta, Georgia 30322, United States.
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Źródło :
Biomacromolecules [Biomacromolecules] 2020 Jul 13; Vol. 21 (7), pp. 2635-2644. Date of Electronic Publication: 2020 May 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Czasopismo naukowe

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