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Tytuł:
Mild ovarian stimulation with letrozole plus fixed dose human menopausal gonadotropin prior to IVF/ICSI for infertile non-obese women with polycystic ovarian syndrome being pre-treated with metformin: a pilot study.
Autorzy:
D'Amato G; Asl Bari, Department of Maternal and Child Health, Reproductive and IVF Unit, Conversano, BA, Italy.
Caringella AM; Asl Bari, Department of Maternal and Child Health, Reproductive and IVF Unit, Conversano, BA, Italy.
Stanziano A; Asl Bari, Department of Maternal and Child Health, Reproductive and IVF Unit, Conversano, BA, Italy.
Cantatore C; Asl Bari, Department of Maternal and Child Health, Reproductive and IVF Unit, Conversano, BA, Italy.
Palini S; Asl Bari, Department of Maternal and Child Health, Reproductive and IVF Unit, Conversano, BA, Italy.
Caroppo E; Asl Bari, Department of Maternal and Child Health, Reproductive and IVF Unit, Conversano, BA, Italy. .; ASL Bari, PTA 'F Jaia', Fisiopatologia della Riproduzione Umana e P.M.A, via de Amicis 30, 70014, Conversano, BA, Italy. .
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Źródło:
Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2018 Sep 14; Vol. 16 (1), pp. 89. Date of Electronic Publication: 2018 Sep 14.
Typ publikacji:
Journal Article
MeSH Terms:
Infertility, Female/*therapy
Metformin/*therapeutic use
Nitriles/*therapeutic use
Polycystic Ovary Syndrome/*complications
Triazoles/*therapeutic use
Adult ; Female ; Gonadotropins/therapeutic use ; Humans ; Letrozole ; Oocyte Retrieval ; Ovarian Hyperstimulation Syndrome ; Ovulation Induction/methods ; Pilot Projects ; Pregnancy ; Pregnancy Rate ; Retrospective Studies ; Sperm Injections, Intracytoplasmic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The VEGF and PEDF levels in the follicular fluid of patients co- treated with LETROZOLE and gonadotropins during the stimulation cycle.
Autorzy:
Haas J; Division of Reproductive Sciences, University of Toronto, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada. .; TRIO fertility partners, 655 Bay St 11th floor, Toronto, ON, M5G 2K4, Canada. .; Department of Obstetrics and Gynecology, Sheba Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Hashomer, Israel. .
Bassil R; Division of Reproductive Sciences, University of Toronto, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada.; TRIO fertility partners, 655 Bay St 11th floor, Toronto, ON, M5G 2K4, Canada.
Gonen N; Division of Reproductive Sciences, University of Toronto, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada.; TRIO fertility partners, 655 Bay St 11th floor, Toronto, ON, M5G 2K4, Canada.
Meriano J; Division of Reproductive Sciences, University of Toronto, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada.; TRIO fertility partners, 655 Bay St 11th floor, Toronto, ON, M5G 2K4, Canada.
Jurisicova A; Division of Reproductive Sciences, University of Toronto, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada.; TRIO fertility partners, 655 Bay St 11th floor, Toronto, ON, M5G 2K4, Canada.
Casper RF; Division of Reproductive Sciences, University of Toronto, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada.; TRIO fertility partners, 655 Bay St 11th floor, Toronto, ON, M5G 2K4, Canada.
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Źródło:
Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2018 May 29; Vol. 16 (1), pp. 54. Date of Electronic Publication: 2018 May 29.
Typ publikacji:
Clinical Trial; Journal Article
MeSH Terms:
Eye Proteins/*metabolism
Follicular Fluid/*metabolism
Gonadotropins/*metabolism
Nerve Growth Factors/*metabolism
Nitriles/*administration & dosage
Ovulation Induction/*methods
Serpins/*metabolism
Triazoles/*administration & dosage
Vascular Endothelial Growth Factor A/*metabolism
Adult ; Aromatase Inhibitors/administration & dosage ; Drug Therapy, Combination ; Female ; Humans ; Infertility, Female/drug therapy ; Infertility, Female/metabolism ; Letrozole ; Male ; Pregnancy ; Prospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Orbital fat regeneration following hormonal treatment of metastatic breast carcinoma.
Autorzy:
Alameddine RM; a Division of Oculofacial Plastic and Reconstructive Surgery, UC San Diego Department of Ophthalmology , Shiley Eye Institute , La Jolla , CA , USA.; b Department of Ophthalmology , American University of Beirut Medical Center , Beirut , Lebanon.
Ko AC; a Division of Oculofacial Plastic and Reconstructive Surgery, UC San Diego Department of Ophthalmology , Shiley Eye Institute , La Jolla , CA , USA.
Mimura M; a Division of Oculofacial Plastic and Reconstructive Surgery, UC San Diego Department of Ophthalmology , Shiley Eye Institute , La Jolla , CA , USA.
Parker BA; c Department of Medicine , UC San Diego Moores Cancer Center , La Jolla , CA , USA.
Lin JH; d UC San Diego Department of Pathology , San Diego , California , USA.; f Veterans Affairs San Diego Healthcare System , San Diego , California , USA.
Korn BS; a Division of Oculofacial Plastic and Reconstructive Surgery, UC San Diego Department of Ophthalmology , Shiley Eye Institute , La Jolla , CA , USA.; e Division of Plastic Surgery , UC San Diego Department of Surgery , La Jolla , CA , USA.
Kikkawa DO; a Division of Oculofacial Plastic and Reconstructive Surgery, UC San Diego Department of Ophthalmology , Shiley Eye Institute , La Jolla , CA , USA.; e Division of Plastic Surgery , UC San Diego Department of Surgery , La Jolla , CA , USA.
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Źródło:
Orbit (Amsterdam, Netherlands) [Orbit] 2018 Jun; Vol. 37 (3), pp. 187-190. Date of Electronic Publication: 2017 Oct 26.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Adipose Tissue/*physiology
Aromatase Inhibitors/*therapeutic use
Breast Neoplasms/*drug therapy
Carcinoma, Lobular/*drug therapy
Enophthalmos/*etiology
Nitriles/*therapeutic use
Orbit/*physiology
Orbital Neoplasms/*drug therapy
Regeneration/*physiology
Triazoles/*therapeutic use
Aged ; Antineoplastic Agents/therapeutic use ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/pathology ; Carcinoma, Lobular/diagnostic imaging ; Carcinoma, Lobular/secondary ; Enophthalmos/diagnostic imaging ; Enophthalmos/physiopathology ; Female ; Humans ; Letrozole ; Orbital Neoplasms/diagnostic imaging ; Orbital Neoplasms/secondary ; Tomography, X-Ray Computed
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clomiphene citrate combined with metformin versus letrozole for induction of ovulation in clomiphene-resistant polycystic ovary syndrome: a randomized clinical trial.
Autorzy:
Rezk M; a Department of Obstetrics and Gynaecology, Faculty of Medicine , Menoufia University , Shibin El-Kom City , Egypt.
Shaheen AE; a Department of Obstetrics and Gynaecology, Faculty of Medicine , Menoufia University , Shibin El-Kom City , Egypt.
Saif El-Nasr I; a Department of Obstetrics and Gynaecology, Faculty of Medicine , Menoufia University , Shibin El-Kom City , Egypt.
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Źródło:
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2018 Apr; Vol. 34 (4), pp. 298-300. Date of Electronic Publication: 2017 Oct 27.
Typ publikacji:
Comparative Study; Journal Article; Randomized Controlled Trial
MeSH Terms:
Clomiphene/*administration & dosage
Fertility Agents, Female/*administration & dosage
Metformin/*administration & dosage
Nitriles/*administration & dosage
Ovulation Induction/*methods
Polycystic Ovary Syndrome/*drug therapy
Triazoles/*administration & dosage
Adult ; Clomiphene/therapeutic use ; Female ; Fertility Agents, Female/therapeutic use ; Humans ; Letrozole ; Metformin/therapeutic use ; Nitriles/therapeutic use ; Ovulation/drug effects ; Pregnancy ; Pregnancy Rate ; Treatment Outcome ; Triazoles/therapeutic use ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Optimization and validation of RP-HPLC method for simultaneous estimation of palbociclib and letrozole.
Autorzy:
Dange Y; a Rajarambapu College of Pharmacy , Sangli , India.
Bhinge S; b Rajarambapu College of Pharmacy, Pharmaceutical Chemistry , Sangli , India.
Salunkhe V; a Rajarambapu College of Pharmacy , Sangli , India.
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Źródło:
Toxicology mechanisms and methods [Toxicol Mech Methods] 2018 Mar; Vol. 28 (3), pp. 187-194. Date of Electronic Publication: 2017 Nov 03.
Typ publikacji:
Journal Article; Validation Study
MeSH Terms:
Technology, Pharmaceutical*/standards
Antineoplastic Agents/*analysis
Aromatase Inhibitors/*analysis
Nitriles/*analysis
Piperazines/*analysis
Protein Kinase Inhibitors/*analysis
Pyridines/*analysis
Triazoles/*analysis
Antineoplastic Agents/chemistry ; Antineoplastic Agents/isolation & purification ; Aromatase Inhibitors/chemistry ; Aromatase Inhibitors/isolation & purification ; Calibration ; Chromatography, High Pressure Liquid ; Chromatography, Reverse-Phase ; Drug Combinations ; Guidelines as Topic ; India ; Letrozole ; Limit of Detection ; Molecular Structure ; Nitriles/chemistry ; Nitriles/isolation & purification ; Piperazines/chemistry ; Piperazines/isolation & purification ; Protein Kinase Inhibitors/chemistry ; Protein Kinase Inhibitors/isolation & purification ; Pyridines/chemistry ; Pyridines/isolation & purification ; Reproducibility of Results ; Spectrophotometry, Ultraviolet ; Triazoles/chemistry ; Triazoles/isolation & purification ; United States ; United States Food and Drug Administration
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparison of clomiphene citrate and letrozole for ovulation induction in women with polycystic ovary syndrome: a prospective randomized trial.
Autorzy:
Liu C; a Department of Obstetrics and Gynecology , West China Second University Hospital of Sichuan University , Sichuan Sheng , PR China.
Feng G; a Department of Obstetrics and Gynecology , West China Second University Hospital of Sichuan University , Sichuan Sheng , PR China.; b Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital , PR China.
Huang W; a Department of Obstetrics and Gynecology , West China Second University Hospital of Sichuan University , Sichuan Sheng , PR China.
Wang Q; a Department of Obstetrics and Gynecology , West China Second University Hospital of Sichuan University , Sichuan Sheng , PR China.
Yang S; a Department of Obstetrics and Gynecology , West China Second University Hospital of Sichuan University , Sichuan Sheng , PR China.
Tan J; a Department of Obstetrics and Gynecology , West China Second University Hospital of Sichuan University , Sichuan Sheng , PR China.
Fu J; a Department of Obstetrics and Gynecology , West China Second University Hospital of Sichuan University , Sichuan Sheng , PR China.
Liu D; a Department of Obstetrics and Gynecology , West China Second University Hospital of Sichuan University , Sichuan Sheng , PR China.
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Źródło:
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2017 Nov; Vol. 33 (11), pp. 872-876. Date of Electronic Publication: 2017 May 30.
Typ publikacji:
Comparative Study; Journal Article; Randomized Controlled Trial
MeSH Terms:
Ovulation Induction*
Clomiphene/*therapeutic use
Hormone Antagonists/*therapeutic use
Infertility, Female/*drug therapy
Nitriles/*therapeutic use
Polycystic Ovary Syndrome/*complications
Triazoles/*therapeutic use
Adult ; Female ; Humans ; Infertility, Female/etiology ; Letrozole ; Pregnancy ; Prospective Studies ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Neoadjuvant everolimus plus letrozole versus fluorouracil, epirubicin and cyclophosphamide for ER-positive, HER2-negative breast cancer: study protocol for a randomized pilot trial.
Autorzy:
Wu W; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Yanjiang West Road 107#, Guangzhou, 510120, China.
Deng H; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Yanjiang West Road 107#, Guangzhou, 510120, China.
Rao N; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Yanjiang West Road 107#, Guangzhou, 510120, China.
You N; Department of Statistical Science, School of Mathematics and Southern China Research Center of Statistical Science, Sun Yat-Sen University, Guangzhou, 510275, China.
Yang Y; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Yanjiang West Road 107#, Guangzhou, 510120, China.
Cao M; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Yanjiang West Road 107#, Guangzhou, 510120, China. .
Liu J; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Yanjiang West Road 107#, Guangzhou, 510120, China. .
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Źródło:
Trials [Trials] 2017 Oct 25; Vol. 18 (1), pp. 497. Date of Electronic Publication: 2017 Oct 25.
Typ publikacji:
Clinical Trial, Phase II; Comparative Study; Journal Article; Randomized Controlled Trial
MeSH Terms:
Neoadjuvant Therapy*/adverse effects
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Biomarkers, Tumor/*analysis
Breast Neoplasms/*drug therapy
Cyclophosphamide/*administration & dosage
Epirubicin/*administration & dosage
Everolimus/*administration & dosage
Fluorouracil/*administration & dosage
Nitriles/*administration & dosage
Receptor, ErbB-2/*analysis
Receptors, Estrogen/*analysis
Triazoles/*administration & dosage
Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Breast Neoplasms/chemistry ; Breast Neoplasms/pathology ; Chemotherapy, Adjuvant ; China ; Clinical Protocols ; Cyclophosphamide/adverse effects ; Everolimus/adverse effects ; Feasibility Studies ; Female ; Fluorouracil/adverse effects ; Humans ; Letrozole ; Lymphatic Metastasis ; Nitriles/adverse effects ; Pilot Projects ; Postmenopause ; Research Design ; Treatment Outcome ; Triazoles/adverse effects ; Tumor Burden
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Does daily co-administration of letrozole and gonadotropins during ovarian stimulation improve IVF outcome?
Autorzy:
Haas J; Division of Reproductive Sciences, University of Toronto, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada. .; TRIO fertility partners, 655 Bay St, Toronto, ON, M5G 2K4, Canada. .; Chaim Sheba medical Center, Tel Hashomer, affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. .
Bassil R; Division of Reproductive Sciences, University of Toronto, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.; TRIO fertility partners, 655 Bay St, Toronto, ON, M5G 2K4, Canada.
Meriano J; Division of Reproductive Sciences, University of Toronto, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.; TRIO fertility partners, 655 Bay St, Toronto, ON, M5G 2K4, Canada.
Samara N; Division of Reproductive Sciences, University of Toronto, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.; TRIO fertility partners, 655 Bay St, Toronto, ON, M5G 2K4, Canada.
Barzilay E; Division of Reproductive Sciences, University of Toronto, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.; TRIO fertility partners, 655 Bay St, Toronto, ON, M5G 2K4, Canada.; Chaim Sheba medical Center, Tel Hashomer, affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Gonen N; Division of Reproductive Sciences, University of Toronto, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.; TRIO fertility partners, 655 Bay St, Toronto, ON, M5G 2K4, Canada.
Casper RF; Division of Reproductive Sciences, University of Toronto, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.; TRIO fertility partners, 655 Bay St, Toronto, ON, M5G 2K4, Canada.
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Źródło:
Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2017 Aug 30; Vol. 15 (1), pp. 70. Date of Electronic Publication: 2017 Aug 30.
Typ publikacji:
Journal Article
MeSH Terms:
Fertilization in Vitro*
Pregnancy Rate*
Fertility Agents, Female/*administration & dosage
Gonadotropins/*administration & dosage
Nitriles/*administration & dosage
Ovulation Induction/*methods
Triazoles/*administration & dosage
Adult ; Case-Control Studies ; Drug Administration Schedule ; Drug Therapy, Combination ; Female ; Humans ; Letrozole ; Oocyte Retrieval/methods ; Pregnancy ; Retrospective Studies ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Comparison of the effects of nobiletin and letrozole on the activity and expression of aromatase in the MCF-7 breast cancer cell line.
Autorzy:
Rahideh ST; a Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Keramatipour M; b Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Nourbakhsh M; c Department of Biochemistry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Koohdani F; d Department of Molecular and Cellular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
Hoseini M; e Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Talebi S; f Department of Genetics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Shidfar F; a Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
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Źródło:
Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2017 Aug; Vol. 95 (4), pp. 468-473. Date of Electronic Publication: 2017 Feb 01.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Aromatase/*metabolism
Breast Neoplasms/*enzymology
Flavones/*pharmacology
Gene Expression Regulation, Enzymologic/*drug effects
Gene Expression Regulation, Neoplastic/*drug effects
Nitriles/*pharmacology
Triazoles/*pharmacology
Aromatase/genetics ; Breast Neoplasms/pathology ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Flavones/administration & dosage ; Humans ; Letrozole ; MCF-7 Cells ; Nitriles/administration & dosage ; Structure-Activity Relationship ; Triazoles/administration & dosage
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Letrozole combined with low dose highly purified HMG for ovulation induction in clomiphene citrate-resistant infertile Chinese women with polycystic ovary syndrome: a prospective study.
Autorzy:
Zhao Y; a Department of Gynecological Endocrinology , Beijing Obstetrics and Gynecology Hospital, Capital Medical University , Beijing , PR China and.
Ruan X; a Department of Gynecological Endocrinology , Beijing Obstetrics and Gynecology Hospital, Capital Medical University , Beijing , PR China and.; b Department of Women's Health , University Hospital and Faculty of Medicine of the Eberhard Karls University Tuebingen , Tuebingen , Germany.
Mueck AO; a Department of Gynecological Endocrinology , Beijing Obstetrics and Gynecology Hospital, Capital Medical University , Beijing , PR China and.; b Department of Women's Health , University Hospital and Faculty of Medicine of the Eberhard Karls University Tuebingen , Tuebingen , Germany.
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Źródło:
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2017 Jun; Vol. 33 (6), pp. 462-466. Date of Electronic Publication: 2017 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
Aromatase Inhibitors/*administration & dosage
Fertility Agents, Female/*administration & dosage
Menotropins/*administration & dosage
Nitriles/*administration & dosage
Ovulation Induction/*methods
Triazoles/*administration & dosage
Adult ; Clomiphene ; Female ; Humans ; Letrozole ; Pregnancy ; Pregnancy Rate ; Prospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Neoadjuvant letrozole for postmenopausal estrogen receptor-positive, HER2-negative breast cancer patients, a study from the Danish Breast Cancer Cooperative Group (DBCG).
Autorzy:
Skriver SK; a Department of Oncology , Rigshospitalet , Copenhagen , Denmark.
Laenkholm AV; b Department of Surgical Pathology , Zealand University Hospital , Slagelse , Denmark.
Rasmussen BB; c Department of Pathology , Herlev Hospital , Herlev , Denmark.
Handler J; d Department of Breast Surgery , Sygehus Soenderjylland , Aabenraa , Denmark.
Grundtmann B; e Department of Breast Surgery , Ringsted Sygehus , Ringsted , Denmark.
Tvedskov TF; f Department of Breast Surgery , Rigshospitalet , Copenhagen , Denmark.
Christiansen P; g Breast Unit, Aarhus University Hospital/Randers Regional Hospital , Aarhus , Denmark.
Knoop AS; a Department of Oncology , Rigshospitalet , Copenhagen , Denmark.
Jensen MB; h Danish Breast Cancer Cooperative Group Secretariat, Rigshospitalet , Copenhagen , Denmark.
Ejlertsen B; a Department of Oncology , Rigshospitalet , Copenhagen , Denmark.; h Danish Breast Cancer Cooperative Group Secretariat, Rigshospitalet , Copenhagen , Denmark.
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Źródło:
Acta oncologica (Stockholm, Sweden) [Acta Oncol] 2018 Jan; Vol. 57 (1), pp. 31-37. Date of Electronic Publication: 2017 Nov 23.
Typ publikacji:
Clinical Trial, Phase II; Journal Article; Multicenter Study
MeSH Terms:
Neoadjuvant Therapy*
Aromatase Inhibitors/*therapeutic use
Breast Neoplasms/*therapy
Carcinoma, Ductal, Breast/*therapy
Nitriles/*therapeutic use
Triazoles/*therapeutic use
Aged ; Aged, 80 and over ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Carcinoma, Ductal, Breast/metabolism ; Carcinoma, Ductal, Breast/pathology ; Denmark ; Female ; Humans ; Letrozole ; Lymph Node Excision ; Mastectomy ; Mastectomy, Segmental ; Middle Aged ; Postmenopause ; Receptors, Estrogen/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Soy isoflavones exert beneficial effects on letrozole-induced rat polycystic ovary syndrome (PCOS) model through anti-androgenic mechanism.
Autorzy:
Rajan RK; a Department of Pharmacology , PSG College of Pharmacy , Coimbatore , Tamil Nadu , India.
M SS; b Department of Pharmaceutical Analysis , PSG College of Pharmacy , Coimbatore , Tamil Nadu , India.
Balaji B; a Department of Pharmacology , PSG College of Pharmacy , Coimbatore , Tamil Nadu , India.
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Źródło:
Pharmaceutical biology [Pharm Biol] 2017 Dec; Vol. 55 (1), pp. 242-251.
Typ publikacji:
Journal Article
MeSH Terms:
Nitriles*
Triazoles*
Androgen Antagonists/*pharmacology
Isoflavones/*pharmacology
Ovary/*drug effects
Phytoestrogens/*pharmacology
Polycystic Ovary Syndrome/*prevention & control
Glycine max/*chemistry
Uterus/*drug effects
17-Hydroxysteroid Dehydrogenases/metabolism ; 3-Hydroxysteroid Dehydrogenases/metabolism ; Androgen Antagonists/isolation & purification ; Animals ; Antioxidants/isolation & purification ; Antioxidants/pharmacology ; Biomarkers/blood ; Blood Glucose/drug effects ; Blood Glucose/metabolism ; Cholesterol/blood ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Estradiol/blood ; Estrous Cycle/drug effects ; Female ; Isoflavones/isolation & purification ; Letrozole ; Ovary/metabolism ; Ovary/pathology ; Oxidative Stress/drug effects ; Phytoestrogens/isolation & purification ; Phytotherapy ; Plants, Medicinal ; Polycystic Ovary Syndrome/blood ; Polycystic Ovary Syndrome/chemically induced ; Polycystic Ovary Syndrome/pathology ; Rats, Sprague-Dawley ; Testosterone/blood ; Time Factors ; Uterus/metabolism ; Uterus/pathology ; Weight Gain/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Efficacy of Letrozole as First-Line Treatment of Postmenopausal Women with Hormone Receptor-Positive Metastatic Breast Cancer in Korea.
Autorzy:
Beom SH; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Oh J; Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Kim TY; Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Lee KH; Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Yang Y; Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Suh KJ; Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Moon HG; Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.; Department of Surgery, Seoul National University Hospital, Seoul, Korea.
Han SW; Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Oh DY; Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Han W; Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.; Department of Surgery, Seoul National University Hospital, Seoul, Korea.
Kim TY; Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Noh DY; Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.; Department of Surgery, Seoul National University Hospital, Seoul, Korea.
Im SA; Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
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Źródło:
Cancer research and treatment [Cancer Res Treat] 2017 Apr; Vol. 49 (2), pp. 454-463. Date of Electronic Publication: 2016 Aug 23.
Typ publikacji:
Journal Article
MeSH Terms:
Postmenopause*
Antineoplastic Agents/*therapeutic use
Aromatase Inhibitors/*therapeutic use
Breast Neoplasms/*drug therapy
Breast Neoplasms/*metabolism
Nitriles/*therapeutic use
Receptors, Estrogen/*metabolism
Receptors, Progesterone/*metabolism
Triazoles/*therapeutic use
Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/adverse effects ; Aromatase Inhibitors/administration & dosage ; Aromatase Inhibitors/adverse effects ; Biomarkers, Tumor ; Breast Neoplasms/mortality ; Breast Neoplasms/pathology ; Combined Modality Therapy ; Female ; Follow-Up Studies ; Humans ; Kaplan-Meier Estimate ; Letrozole ; Middle Aged ; Neoplasm Metastasis ; Nitriles/administration & dosage ; Nitriles/adverse effects ; Receptor, ErbB-2/metabolism ; Republic of Korea ; Survival Analysis ; Treatment Outcome ; Triazoles/administration & dosage ; Triazoles/adverse effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Cost effectiveness of letrozole and purified urinary FSH in treating women with clomiphene citrate-resistant polycystic ovarian syndrome: a randomized controlled trial.
Autorzy:
Hassan A; a Cairo University , Cairo , Egypt.
Shehata N; b Beni-Suef University , Beni-Suef , Egypt.
Wahba A; a Cairo University , Cairo , Egypt.
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Źródło:
Human fertility (Cambridge, England) [Hum Fertil (Camb)] 2017 Apr; Vol. 20 (1), pp. 37-42. Date of Electronic Publication: 2016 Nov 08.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Cost-Benefit Analysis*
Clomiphene/*therapeutic use
Follicle Stimulating Hormone/*therapeutic use
Infertility/*drug therapy
Nitriles/*therapeutic use
Polycystic Ovary Syndrome/*complications
Triazoles/*therapeutic use
Adult ; Aromatase Inhibitors/administration & dosage ; Aromatase Inhibitors/therapeutic use ; Drug Therapy, Combination/economics ; Female ; Fertility Agents, Female/therapeutic use ; Follicle Stimulating Hormone/administration & dosage ; Follicle Stimulating Hormone/economics ; Hormones/administration & dosage ; Hormones/therapeutic use ; Humans ; Infertility/etiology ; Letrozole ; Nitriles/administration & dosage ; Nitriles/economics ; Pregnancy ; Triazoles/administration & dosage ; Triazoles/economics ; Young Adult
Czasopismo naukowe
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Tytuł:
Magnetic iron oxide nanoparticles grafted N-isopropylacrylamide/chitosan copolymer for the extraction and determination of letrozole in human biological samples.
Autorzy:
Khalaj Moazen M; Department of Chemistry, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Ahmad Panahi H; Department of Chemistry, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
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Źródło:
Journal of separation science [J Sep Sci] 2017 Mar; Vol. 40 (5), pp. 1125-1132.
Typ publikacji:
Journal Article
MeSH Terms:
Acrylamides*
Chitosan*
Ferric Compounds*
Magnetite Nanoparticles*
Nitriles/*isolation & purification
Triazoles/*isolation & purification
Humans ; Hydrogen-Ion Concentration ; Letrozole ; Nitriles/blood ; Nitriles/urine ; Solid Phase Extraction ; Spectroscopy, Fourier Transform Infrared ; Triazoles/blood ; Triazoles/urine
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparison of ovarian stimulation response in patients with breast cancer undergoing ovarian stimulation with letrozole and gonadotropins to patients undergoing ovarian stimulation with gonadotropins alone for elective cryopreservation of oocytes†.
Autorzy:
Pereira N; a Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical Center , New York , NY , USA.
Hancock K; a Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical Center , New York , NY , USA.
Cordeiro CN; a Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical Center , New York , NY , USA.
Lekovich JP; a Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical Center , New York , NY , USA.
Schattman GL; a Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical Center , New York , NY , USA.
Rosenwaks Z; a Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical Center , New York , NY , USA.
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Źródło:
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2016 Oct; Vol. 32 (10), pp. 823-826. Date of Electronic Publication: 2016 Apr 26.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
Breast Neoplasms/*drug therapy
Fertility Preservation/*methods
Gonadotropins/*pharmacology
Nitriles/*pharmacology
Oocytes/*drug effects
Ovulation Induction/*methods
Triazoles/*pharmacology
Adult ; Antineoplastic Agents/administration & dosage ; Breast Neoplasms/blood ; Cryopreservation/methods ; Drug Therapy, Combination ; Female ; Gonadotropins/administration & dosage ; Humans ; Letrozole ; Nitriles/administration & dosage ; Treatment Outcome ; Triazoles/administration & dosage
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Differential profile of letrozole and exemestane on bone turnover markers in vinylcyclohexene diepoxide treated ovotoxic female mice.
Autorzy:
Kalam A; Department of Pharmacology, Faculty of Pharmacy, Jamia Hamdard, New Delhi, 110062, India.
Talegaonkar S; Department of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard, New Delhi, 110062, India.
Vohora D; Department of Pharmacology, Faculty of Pharmacy, Jamia Hamdard, New Delhi, 110062, India. , .
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Źródło:
Fundamental & clinical pharmacology [Fundam Clin Pharmacol] 2016 Oct; Vol. 30 (5), pp. 429-39. Date of Electronic Publication: 2016 Jul 26.
Typ publikacji:
Journal Article
MeSH Terms:
Androstadienes/*pharmacology
Aromatase Inhibitors/*pharmacology
Bone Remodeling/*drug effects
Cyclohexenes/*toxicity
Nitriles/*pharmacology
Ovary/*drug effects
Triazoles/*pharmacology
Vinyl Compounds/*toxicity
Androstadienes/toxicity ; Animals ; Aromatase Inhibitors/toxicity ; Biomarkers/blood ; Biomarkers/metabolism ; Bone Density/drug effects ; Bone Density/physiology ; Bone Remodeling/physiology ; Carcinogens/toxicity ; Estradiol/blood ; Female ; Letrozole ; Mice ; Nitriles/toxicity ; Ovary/metabolism ; Ovary/pathology ; Triazoles/toxicity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Reversal of tubo-ovarian atypical epithelial patterns after cessation of ovarian stimulation by letrozole.
Autorzy:
Abdel-Hamid AA; Department of Histology and Cell Biology, Faculty of Medicine, Mansoura University, Mansoura, Egypt. .
Mesbah Y; Department of Obstetrics and Gynecology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Soliman MF; Department of Histology and Cell Biology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
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Źródło:
International journal of experimental pathology [Int J Exp Pathol] 2016 Aug; Vol. 97 (4), pp. 329-336. Date of Electronic Publication: 2016 Sep 01.
Typ publikacji:
Journal Article
MeSH Terms:
Aromatase Inhibitors/*pharmacology
Fallopian Tubes/*drug effects
Nitriles/*pharmacology
Ovary/*drug effects
Ovulation Induction/*methods
Triazoles/*pharmacology
Animals ; Cell Proliferation/drug effects ; Chemokine CCL2/blood ; Cytokines/metabolism ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Epithelium/drug effects ; Epithelium/metabolism ; Epithelium/pathology ; Fallopian Tubes/metabolism ; Fallopian Tubes/pathology ; Female ; Letrozole ; Ovary/metabolism ; Ovary/pathology ; Rats, Sprague-Dawley ; Withholding Treatment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Durable complete remission with aromatase inhibitor therapy in a patient with metastatic uterine carcinosarcoma with poor performance status and coagulation disorders: a case report.
Autorzy:
Martin-Romano P; Department of Oncology, Clínica Universidad de Navarra, Avenida Pío XII 36, 31008, Pamplona, Spain. .
Jurado M; Department of Gynecology, Clínica Universidad de Navarra, Pamplona, Spain.
Idoate MA; Department of Pathology, Clínica Universidad de Navarra, Pamplona, Spain.
Arbea L; Department of Oncology, Clínica Universidad de Navarra, Avenida Pío XII 36, 31008, Pamplona, Spain.
Hernandez-Lizoain JL; Department of General Surgery, Clínica Universidad de Navarra, Pamplona, Spain.
Cano D; Department of Radiology, Clínica Universidad de Navarra, Pamplona, Spain.
Paramo JA; Hematology Service, Clínica Universidad de Navarra, Pamplona, Spain.
Martin-Algarra S; Department of Oncology, Clínica Universidad de Navarra, Avenida Pío XII 36, 31008, Pamplona, Spain.
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Źródło:
Journal of medical case reports [J Med Case Rep] 2017 Apr 19; Vol. 11 (1), pp. 115. Date of Electronic Publication: 2017 Apr 19.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Aromatase Inhibitors/*therapeutic use
Blood Coagulation Disorders/*complications
Bone Neoplasms/*drug therapy
Carcinosarcoma/*complications
Carcinosarcoma/*drug therapy
Nitriles/*therapeutic use
Triazoles/*therapeutic use
Uterine Neoplasms/*complications
Uterine Neoplasms/*drug therapy
Bone Neoplasms/secondary ; Carcinosarcoma/diagnosis ; Carcinosarcoma/pathology ; Female ; Humans ; Letrozole ; Lymphatic Metastasis ; Middle Aged ; Remission Induction ; Shock/etiology ; Uterine Hemorrhage/etiology ; Uterine Neoplasms/diagnosis ; Uterine Neoplasms/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Effects of a single 20 mg dose of letrozole on ovarian function post dominant follicle selection: an exploratory randomized controlled trial.
Autorzy:
Allaway HC; Department of Obstetrics, Gynecology & Reproductive Sciences, College of Medicine, University of Saskatchewan, 103 Hospital Drive, Saskatoon, SK, S7N 0 W8, Canada.; Present Address: Department of Kinesiology, Pennsylvania State University, State College, PA, USA.
Chizen DR; Department of Obstetrics, Gynecology & Reproductive Sciences, College of Medicine, University of Saskatchewan, 103 Hospital Drive, Saskatoon, SK, S7N 0 W8, Canada.
Adams GP; Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Pierson RA; Department of Obstetrics, Gynecology & Reproductive Sciences, College of Medicine, University of Saskatchewan, 103 Hospital Drive, Saskatoon, SK, S7N 0 W8, Canada. .
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Źródło:
Journal of ovarian research [J Ovarian Res] 2017 Jan 21; Vol. 10 (1), pp. 6. Date of Electronic Publication: 2017 Jan 21.
Typ publikacji:
Clinical Trial; Journal Article; Randomized Controlled Trial
MeSH Terms:
Aromatase Inhibitors/*administration & dosage
Nitriles/*administration & dosage
Ovarian Follicle/*drug effects
Ovary/*drug effects
Ovary/*physiology
Triazoles/*administration & dosage
Adolescent ; Adult ; Body Mass Index ; Endometrium/cytology ; Endometrium/physiology ; Female ; Healthy Volunteers ; Hormones/blood ; Humans ; Letrozole ; Luteinization ; Menstrual Cycle ; Ovarian Follicle/cytology ; Ovulation ; Pilot Projects ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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