Autor: "Letson HL" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Changes in plasma alpha-1 acid glycoprotein following hemorrhagic trauma: Possible role in dose differences of ALM drug therapy in rat and pig resuscitation.
Autorzy:: Letson HL; Heart and Trauma Research Laboratory, College of Medicine and Dentistry, James Cook University, Townsville, Queensland, Australia.
Morris JL; Heart and Trauma Research Laboratory, College of Medicine and Dentistry, James Cook University, Townsville, Queensland, Australia.
Dobson GP; Heart and Trauma Research Laboratory, College of Medicine and Dentistry, James Cook University, Townsville, Queensland, Australia.; Pokaż więcej
Źródło:: Pharmacology research & perspectives [Pharmacol Res Perspect] 2023 Oct; Vol. 11 (5), pp. e01133.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Orosomucoid*
Shock, Hemorrhagic*/drug therapy
Female ; Male ; Rats ; Animals ; Swine ; Rats, Sprague-Dawley ; Hemorrhage ; Lidocaine

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Skocz do pozycji: 2.

Tytuł:: Anterior Cruciate Ligament Reconstruction Surgery: Creating a Permissive Healing Phenotype in Military Personnel and Civilians for Faster Recovery.
Autorzy:: Morris JL; Heart and Trauma Research Laboratory, College of Medicine and Dentistry, James Cook University, Townsville 4811, Australia.
McEwen P; The Orthopaedic Research Institute of Queensland (ORIQL), Townsville, Queensland, QLD 4812, Australia.
Letson HL; Heart and Trauma Research Laboratory, College of Medicine and Dentistry, James Cook University, Townsville 4811, Australia.
Dobson GP; Heart and Trauma Research Laboratory, College of Medicine and Dentistry, James Cook University, Townsville 4811, Australia.; Pokaż więcej
Źródło:: Military medicine [Mil Med] 2022 Oct 29; Vol. 187 (11-12), pp. 1310-1317.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Anterior Cruciate Ligament Injuries*/complications
Anterior Cruciate Ligament Injuries*/surgery
Military Personnel*
Anterior Cruciate Ligament Reconstruction*
Osteoarthritis*
Male ; Female ; Humans ; Quality of Life ; Phenotype

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Skocz do pozycji: 3.

Tytuł:: Comparison of intra-articular administration of adenosine, lidocaine and magnesium solution and tranexamic acid for alleviating postoperative inflammation and joint fibrosis in an experimental model of knee arthroplasty.
Autorzy:: Morris JL; Orthopaedic Research Institute of Queensland, Townsville, QLD, Australia. .; Heart and Trauma Research Laboratory, Division of Tropical Health and Medicine, College of Medicine and Dentistry,, James Cook University, Townsville, QLD, 4811, Australia. .
Letson HL; Heart and Trauma Research Laboratory, Division of Tropical Health and Medicine, College of Medicine and Dentistry,, James Cook University, Townsville, QLD, 4811, Australia.
McEwen P; Orthopaedic Research Institute of Queensland, Townsville, QLD, Australia.
Biros E; Heart and Trauma Research Laboratory, Division of Tropical Health and Medicine, College of Medicine and Dentistry,, James Cook University, Townsville, QLD, 4811, Australia.
Dlaska C; Orthopaedic Research Institute of Queensland, Townsville, QLD, Australia.
Hazratwala K; Orthopaedic Research Institute of Queensland, Townsville, QLD, Australia.
Wilkinson M; Orthopaedic Research Institute of Queensland, Townsville, QLD, Australia.
Dobson GP; Heart and Trauma Research Laboratory, Division of Tropical Health and Medicine, College of Medicine and Dentistry,, James Cook University, Townsville, QLD, 4811, Australia.; Pokaż więcej
Źródło:: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2021 Dec 20; Vol. 16 (1), pp. 726. Date of Electronic Publication: 2021 Dec 20.
Typ publikacji:: Journal Article
MeSH Terms:: Adenosine/*administration & dosage
Antifibrinolytic Agents/*administration & dosage
Blood Loss, Surgical/*prevention & control
Fibrosis/*prevention & control
Inflammation/*prevention & control
Lidocaine/*administration & dosage
Magnesium/*administration & dosage
Osteoarthritis, Knee/*surgery
Postoperative Hemorrhage/*prevention & control
Tranexamic Acid/*administration & dosage
Adenosine/therapeutic use ; Administration, Intravenous ; Animals ; Antifibrinolytic Agents/therapeutic use ; Arthroplasty, Replacement, Knee/adverse effects ; Fibrosis/drug therapy ; Inflammation/drug therapy ; Injections, Intra-Articular ; Interleukin-10 ; Interleukin-12 ; Lidocaine/therapeutic use ; Magnesium/therapeutic use ; Male ; Models, Theoretical ; Postoperative Hemorrhage/etiology ; Rats ; Rats, Sprague-Dawley ; Tranexamic Acid/therapeutic use

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Skocz do pozycji: 4.

Tytuł:: Evaluation of bacteriophage as an adjunct therapy for treatment of peri-prosthetic joint infection caused by Staphylococcus aureus.
Autorzy:: Morris JL; Orthopaedic Research Institute of Queensland, Townsville, Queensland, Australia.; College of Medicine and Dentistry, James Cook University, Queensland, Australia.
Letson HL; College of Medicine and Dentistry, James Cook University, Queensland, Australia.
Elliott L; AusPhage Pty Ltd, Townsville, Queensland, Australia.
Grant AL; Orthopaedic Research Institute of Queensland, Townsville, Queensland, Australia.
Wilkinson M; Orthopaedic Research Institute of Queensland, Townsville, Queensland, Australia.
Hazratwala K; Orthopaedic Research Institute of Queensland, Townsville, Queensland, Australia.
McEwen P; Orthopaedic Research Institute of Queensland, Townsville, Queensland, Australia.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2019 Dec 26; Vol. 14 (12), pp. e0226574. Date of Electronic Publication: 2019 Dec 26 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bacteriophages/*physiology
Prosthesis-Related Infections/*therapy
Staphylococcal Infections/*therapy
Staphylococcus aureus/*pathogenicity
Vancomycin/*administration & dosage
Animals ; Bacterial Load/drug effects ; Combined Modality Therapy ; Disease Models, Animal ; Male ; Prosthesis-Related Infections/microbiology ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Staphylococcal Infections/microbiology ; Staphylococcus aureus/drug effects ; Treatment Outcome ; Vancomycin/pharmacology

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Skocz do pozycji: 5.

Tytuł:: Conventional and Specific-Pathogen Free Rats Respond Differently to Anesthesia and Surgical Trauma.
Autorzy:: Letson HL; Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, Queensland, 4811, Australia.
Morris J; Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, Queensland, 4811, Australia.
Biros E; Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, Queensland, 4811, Australia.
Dobson GP; Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, Queensland, 4811, Australia. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Jun 28; Vol. 9 (1), pp. 9399. Date of Electronic Publication: 2019 Jun 28.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Anesthesia*
Surgical Procedures, Operative*/adverse effects
Wounds and Injuries*/etiology
Animals ; Biomarkers ; Blood Coagulation ; Cardiovascular Physiological Phenomena ; Cardiovascular System/physiopathology ; Electrocardiography ; Hemodynamics ; Models, Animal ; Rats ; Rats, Sprague-Dawley ; Specific Pathogen-Free Organisms

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Skocz do pozycji: 6.

Tytuł:: Tranexamic acid is associated with selective increase in inflammatory markers following total knee arthroplasty (TKA): a pilot study.
Autorzy:: Grant AL; The Orthopaedic Research Institute of Queensland (ORIQL), 7 Turner St, Pimlico, Townsville, Queensland, 4812, Australia.; Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, 1 James Cook Drive, Townsville, Queensland, 4811, Australia.
Letson HL; Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, 1 James Cook Drive, Townsville, Queensland, 4811, Australia.
Morris JL; The Orthopaedic Research Institute of Queensland (ORIQL), 7 Turner St, Pimlico, Townsville, Queensland, 4812, Australia.; Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, 1 James Cook Drive, Townsville, Queensland, 4811, Australia.
McEwen P; The Orthopaedic Research Institute of Queensland (ORIQL), 7 Turner St, Pimlico, Townsville, Queensland, 4812, Australia.; Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, 1 James Cook Drive, Townsville, Queensland, 4811, Australia.
Hazratwala K; The Orthopaedic Research Institute of Queensland (ORIQL), 7 Turner St, Pimlico, Townsville, Queensland, 4812, Australia.; Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, 1 James Cook Drive, Townsville, Queensland, 4811, Australia.
Wilkinson M; The Orthopaedic Research Institute of Queensland (ORIQL), 7 Turner St, Pimlico, Townsville, Queensland, 4812, Australia.; Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, 1 James Cook Drive, Townsville, Queensland, 4811, Australia.
Dobson GP; Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, 1 James Cook Drive, Townsville, Queensland, 4811, Australia. .; Pokaż więcej
Źródło:: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2018 Jun 18; Vol. 13 (1), pp. 149. Date of Electronic Publication: 2018 Jun 18.
Typ publikacji:: Journal Article
MeSH Terms:: Arthroplasty, Replacement, Knee*
Antifibrinolytic Agents/*adverse effects
Blood Loss, Surgical/*prevention & control
Inflammation/*blood
Osteoarthritis, Hip/*surgery
Tranexamic Acid/*adverse effects
Aged ; Antifibrinolytic Agents/pharmacology ; Antifibrinolytic Agents/therapeutic use ; Biomarkers/blood ; Blood Coagulation/drug effects ; Female ; Humans ; Inflammation/chemically induced ; Inflammation/etiology ; Male ; Middle Aged ; Pilot Projects ; Prospective Studies ; Tranexamic Acid/pharmacology ; Tranexamic Acid/therapeutic use

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Skocz do pozycji: 7.

Tytuł:: 7.5% NaCl Resuscitation Leads to Abnormal Clot Fibrinolysis after Severe Hemorrhagic Shock and its Correction with 7.5% NaCl Adenosine, Lidocaine, and Mg .
Autorzy:: Letson HL; Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, Queensland 4811, Australia.
Dobson GP; Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, Queensland 4811, Australia.; Pokaż więcej
Źródło:: Journal of emergencies, trauma, and shock [J Emerg Trauma Shock] 2018 Jan-Mar; Vol. 11 (1), pp. 15-24.
Typ publikacji:: Journal Article

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