Temat: "Leucine" - OpacWWW

Skocz do pozycji: 1 1.

Tytuł :: Bach1 plays an important role in angiogenesis through regulation of oxidative stress.
Autorzy :: Yusoff FM; Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Maruhashi T; Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Kawano KI; Division of Regeneration and Medicine, Medical Center for Translational and Clinical Research, Hiroshima University Hospital, Hiroshima, Japan.
Nakashima A; Department of Stem Cell Biology and Medicine, Graduate School of Biomedical and Sciences, Hiroshima University, Hiroshima, Japan.
Chayama K; Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Tashiro S; Department of Cellular Biology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Igarashi K; Department of Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.
Higashi Y; Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan; Division of Regeneration and Medicine, Medical Center for Translational and Clinical Research, Hiroshima University Hospital, Hiroshima, Japan. Electronic address: .; Pokaż więcej
Źródło :: Microvascular research [Microvasc Res] 2021 Mar; Vol. 134, pp. 104126. Date of Electronic Publication: 2020 Dec 26.
Typ publikacji :: Journal Article
MeSH Terms :: Neovascularization, Physiologic*
Oxidative Stress*
Basic-Leucine Zipper Transcription Factors/*metabolism
Endothelial Cells/*metabolism
Ischemia/*metabolism
Muscle, Skeletal/*blood supply
Animals ; Apoptosis ; Basic-Leucine Zipper Transcription Factors/deficiency ; Basic-Leucine Zipper Transcription Factors/genetics ; Blood Flow Velocity ; Cell Movement ; Cells, Cultured ; Disease Models, Animal ; Endothelial Cells/pathology ; Heme Oxygenase-1/metabolism ; Hindlimb ; Ischemia/genetics ; Ischemia/pathology ; Ischemia/physiopathology ; Male ; Membrane Proteins/metabolism ; Mice, Inbred C57BL ; Mice, Knockout, ApoE ; Microvascular Density ; Regional Blood Flow ; Signal Transduction
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 2 2.

Tytuł :: BACH1 recruits NANOG and histone H3 lysine 4 methyltransferase MLL/SET1 complexes to regulate enhancer-promoter activity and maintains pluripotency.
Autorzy :: Niu C; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Shanghai Key Laboratory of Bioactive Small Molecules; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Wang S; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Shanghai Key Laboratory of Bioactive Small Molecules; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Guo J; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Shanghai Key Laboratory of Bioactive Small Molecules; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Wei X; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Shanghai Key Laboratory of Bioactive Small Molecules; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Jia M; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Shanghai Key Laboratory of Bioactive Small Molecules; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Chen Z; CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.; Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Center for Quantitative Biology (CQB), Peking University, Beijing 100871, China.
Gong W; CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Qin Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Shanghai Key Laboratory of Bioactive Small Molecules; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Wang X; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Shanghai Key Laboratory of Bioactive Small Molecules; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Zhi X; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Shanghai Key Laboratory of Bioactive Small Molecules; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Lu M; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Shanghai Key Laboratory of Bioactive Small Molecules; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Chen S; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Shanghai Key Laboratory of Bioactive Small Molecules; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Gu M; Perinatal Institute, Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Zhang J; Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Han JJ; CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.; Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Center for Quantitative Biology (CQB), Peking University, Beijing 100871, China.
Lan F; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Shanghai Key Laboratory of Bioactive Small Molecules; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Meng D; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Shanghai Key Laboratory of Bioactive Small Molecules; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.; Pokaż więcej
Źródło :: Nucleic acids research [Nucleic Acids Res] 2021 Feb 26; Vol. 49 (4), pp. 1972-1986.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Enhancer Elements, Genetic*
Promoter Regions, Genetic*
Basic-Leucine Zipper Transcription Factors/*metabolism
Embryonic Stem Cells/*metabolism
Histone-Lysine N-Methyltransferase/*metabolism
Nanog Homeobox Protein/*metabolism
Animals ; Basic-Leucine Zipper Transcription Factors/chemistry ; Basic-Leucine Zipper Transcription Factors/physiology ; Cell Line ; Cells, Cultured ; Chromatin/metabolism ; Histones/metabolism ; Mice ; Octamer Transcription Factor-3/metabolism ; Protein Domains ; SOXB1 Transcription Factors/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 3 3.

Tytuł :: Structural basis for the inhibition of the SARS-CoV-2 main protease by the anti-HCV drug narlaprevir.
Autorzy :: Bai Y; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, 100049, China.; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China.
Ye F; NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control & Prevention, Chinese Center for Disease Control and Prevention, China CDC, Beijing, 102206, China.
Feng Y; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, 100049, China.; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China.
Liao H; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, 100049, China.; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China.
Song H; Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, 100101, China.
Qi J; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, 100049, China.; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China.
Gao GF; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, 100049, China.; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China.; Center for Influenza Research and Early Warning (CASCIRE), CAS-TWAS Center of Excellence for Emerging Infectious Disease (CEEID), Chinese Academy of Sciences, Beijing, 100101, China.
Tan W; Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, 100101, China. .
Fu L; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China. .; Center for Influenza Research and Early Warning (CASCIRE), CAS-TWAS Center of Excellence for Emerging Infectious Disease (CEEID), Chinese Academy of Sciences, Beijing, 100101, China. .
Shi Y; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, 100049, China. .; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China. .; Center for Influenza Research and Early Warning (CASCIRE), CAS-TWAS Center of Excellence for Emerging Infectious Disease (CEEID), Chinese Academy of Sciences, Beijing, 100101, China. .; Pokaż więcej
Źródło :: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2021 Feb 04; Vol. 6 (1), pp. 51. Date of Electronic Publication: 2021 Feb 04.
Typ publikacji :: Letter; Research Support, Non-U.S. Gov't
MeSH Terms :: Coronavirus 3C Proteases*/antagonists & inhibitors
Coronavirus 3C Proteases*/chemistry
COVID-19/*enzymology
Cyclopropanes/*chemistry
Cysteine Proteinase Inhibitors/*chemistry
Leucine/*analogs & derivatives
Proline/*analogs & derivatives
SARS-CoV-2/*enzymology
Sulfones/*chemistry
Urea/*chemistry
COVID-19/drug therapy ; Cyclopropanes/pharmacology ; Cysteine Proteinase Inhibitors/pharmacology ; Hepacivirus/enzymology ; Humans ; Leucine/chemistry ; Leucine/pharmacology ; Proline/chemistry ; Proline/pharmacology ; Sulfones/pharmacology ; Urea/pharmacology
: Raport

Szczegóły

Skocz do pozycji: 4 4.

Tytuł :: Higher content of microcystin-leucine-arginine promotes the survival of intrahepatic cholangiocarcinoma cells via regulating SET resulting in the poorer prognosis of patients.
Autorzy :: Gu S; Department of Hepatopancreatobiliary Surgery, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, China.; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, China.; Department of Clinical Pharmacology, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Hangzhou First People's Hospital, Hangzhou, China.
He W; Department of Neurosurgery, Affiliated Aoyang Hospital of Jiangsu University, Zhangjiagang, China.
Yan M; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, China.; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, China.
He J; Department of Radiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Zhou Q; Department of Radiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Yan X; Department of Hepatopancreatobiliary Surgery, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Fu X; Department of Hepatopancreatobiliary Surgery, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, China.; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, China.
Chen J; Department of Pathology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Han X; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, China.; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, China.
Qiu Y; Department of Hepatopancreatobiliary Surgery, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.; Pokaż więcej
Źródło :: Cell proliferation [Cell Prolif] 2021 Feb; Vol. 54 (2), pp. e12961. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji :: Journal Article
MeSH Terms :: Arginine/*metabolism
Bile Duct Neoplasms/*pathology
Cholangiocarcinoma/*pathology
DNA-Binding Proteins/*metabolism
Histone Chaperones/*metabolism
Leucine/*metabolism
Microcystins/*metabolism
Arginine/pharmacology ; Bile Duct Neoplasms/mortality ; Bile Duct Neoplasms/surgery ; Cell Proliferation/drug effects ; Cholangiocarcinoma/mortality ; Cholangiocarcinoma/surgery ; DNA-Binding Proteins/antagonists & inhibitors ; DNA-Binding Proteins/genetics ; Disease-Free Survival ; Female ; Histone Chaperones/antagonists & inhibitors ; Histone Chaperones/genetics ; Humans ; Leucine/pharmacology ; Male ; Microcystins/pharmacology ; Middle Aged ; Neoplasm Recurrence, Local ; Prognosis ; Proportional Hazards Models ; RNA Interference ; RNA, Messenger/metabolism ; RNA, Small Interfering/metabolism ; Retrospective Studies ; Risk Factors
: Czasopismo naukowe

Szczegóły Pełny tekst

Skocz do pozycji: 5 5.

Tytuł :: Reply to DJ Millward.
Autorzy :: Szwiega S; From the Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.
Pencharz PB; Departments of Nutritional Sciences, Medican Science Building, 1 King's College Circle, Toronto, ON, Canada.; Paediatrics, 555 University Ave, Black Wing, Toronto, ON, Canada.
Courtney-Martin G; Departments of Nutritional Sciences, Medican Science Building, 1 King's College Circle, Toronto, ON, Canada.; Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, Ontario, Canada.; Pokaż więcej
Źródło :: The American journal of clinical nutrition [Am J Clin Nutr] 2021 Apr 06; Vol. 113 (4), pp. 1055-1056.
Typ publikacji :: Journal Article; Comment
MeSH Terms :: Leucine*
Aged ; Female ; Humans ; Male ; Nutritional Requirements
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 6 6.

Tytuł :: BACH2-mediated FOS confers cytarabine resistance via stromal microenvironment alterations in pediatric ALL.
Autorzy :: Zhang H; Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.
Zhang R; Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics (Capital Medical University), Key Laboratory of Major Diseases in Children, Ministry of Education, Hematology Oncology Center, Beijing Children's Hospital, National Center for Children's Health, Capital Medical University, Beijing, China.
Zheng X; Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics (Capital Medical University), Key Laboratory of Major Diseases in Children, Ministry of Education, Hematology Oncology Center, Beijing Children's Hospital, National Center for Children's Health, Capital Medical University, Beijing, China.
Sun M; Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.
Fan J; Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics (Capital Medical University), Key Laboratory of Major Diseases in Children, Ministry of Education, Hematology Oncology Center, Beijing Children's Hospital, National Center for Children's Health, Capital Medical University, Beijing, China.
Fang C; Department of Hematology and Oncology, Kunming Children's Hospital (Children's Hospital of Kunming Medical University, Yunnan Children's Medical Center), Kunming, China.
Tian X; Department of Hematology and Oncology, Kunming Children's Hospital (Children's Hospital of Kunming Medical University, Yunnan Children's Medical Center), Kunming, China.
Zheng H; Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics (Capital Medical University), Key Laboratory of Major Diseases in Children, Ministry of Education, Hematology Oncology Center, Beijing Children's Hospital, National Center for Children's Health, Capital Medical University, Beijing, China.; Pokaż więcej
Źródło :: Cancer science [Cancer Sci] 2021 Mar; Vol. 112 (3), pp. 1235-1250. Date of Electronic Publication: 2021 Jan 22.
Typ publikacji :: Journal Article; Observational Study
MeSH Terms :: Antimetabolites, Antineoplastic/*pharmacology
Basic-Leucine Zipper Transcription Factors/*metabolism
Drug Resistance, Neoplasm/*genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy
Proto-Oncogene Proteins c-fos/*metabolism
Animals ; Antimetabolites, Antineoplastic/therapeutic use ; Basic-Leucine Zipper Transcription Factors/genetics ; Cell Proliferation/genetics ; Child ; Child, Preschool ; Cytarabine/pharmacology ; Cytarabine/therapeutic use ; Female ; Gene Expression Regulation, Leukemic ; Gene Knockdown Techniques ; Humans ; Infant ; Male ; Mesenchymal Stem Cells ; Mice ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/blood ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Primary Cell Culture ; Tumor Cells, Cultured ; Tumor Microenvironment/genetics ; Xenograft Model Antitumor Assays
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 7 7.

Tytuł :: Peach PpSnRK1α interacts with bZIP11 and maintains trehalose balance in plants.
Autorzy :: Zhang S; State Key Laboratory of Crop Biology, College of Horticulture Science and Engineering, Shandong Agricultural University, Tai'an, China.
Wang H; College of Horticulture, Northwest A & F University, Yang Ling, Shaanxi, 712100, China.
Luo J; State Key Laboratory of Crop Biology, College of Horticulture Science and Engineering, Shandong Agricultural University, Tai'an, China.
Yu W; State Key Laboratory of Crop Biology, College of Horticulture Science and Engineering, Shandong Agricultural University, Tai'an, China.
Xiao Y; State Key Laboratory of Crop Biology, College of Horticulture Science and Engineering, Shandong Agricultural University, Tai'an, China. Electronic address: .
Peng F; State Key Laboratory of Crop Biology, College of Horticulture Science and Engineering, Shandong Agricultural University, Tai'an, China. Electronic address: .; Pokaż więcej
Źródło :: Plant physiology and biochemistry : PPB [Plant Physiol Biochem] 2021 Mar; Vol. 160, pp. 377-385. Date of Electronic Publication: 2021 Jan 28.
Typ publikacji :: Journal Article
MeSH Terms :: Basic-Leucine Zipper Transcription Factors/*metabolism
Protein-Serine-Threonine Kinases/*metabolism
Prunus persica/*genetics
Trehalose/*metabolism
Arabidopsis/genetics ; Arabidopsis/metabolism ; Basic-Leucine Zipper Transcription Factors/genetics ; Gene Expression Regulation, Plant ; Plants, Genetically Modified/metabolism ; Protein-Serine-Threonine Kinases/genetics ; Sugar Phosphates
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 8 8.

Tytuł :: The gene NtMYC2a acts as a 'master switch' in the regulation of JA-induced nicotine accumulation in tobacco.
Autorzy :: Sui X; Tobacco Breeding Center, Yunnan Academy of Tobacco Agricultural Sciences, Kunming, China.
He X; Technology Center, Baoshan Oriental Tobacco Company, Baoshan, China.
Song Z; Tobacco Breeding Center, Yunnan Academy of Tobacco Agricultural Sciences, Kunming, China.
Gao Y; Tobacco Breeding Center, Yunnan Academy of Tobacco Agricultural Sciences, Kunming, China.
Zhao L; Tobacco Breeding Center, Yunnan Academy of Tobacco Agricultural Sciences, Kunming, China.
Jiao F; Tobacco Breeding Center, Yunnan Academy of Tobacco Agricultural Sciences, Kunming, China.
Kong G; Chemical Analysis Center, Yunnan Academy of Tobacco Agricultural Sciences, Kunming, China.
Li Y; Tobacco Breeding Center, Yunnan Academy of Tobacco Agricultural Sciences, Kunming, China.
Han S; College of Life Sciences, Beijing Normal University, Beijing, China.
Wang B; Tobacco Breeding Center, Yunnan Academy of Tobacco Agricultural Sciences, Kunming, China.; Pokaż więcej
Źródło :: Plant biology (Stuttgart, Germany) [Plant Biol (Stuttg)] 2021 Mar; Vol. 23 (2), pp. 317-326. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :: Journal Article
MeSH Terms :: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors*/metabolism
Cyclopentanes*/pharmacology
Gene Expression Regulation, Plant*/genetics
Nicotine*/metabolism
Oxylipins*/pharmacology
Tobacco*/drug effects
Tobacco*/genetics
Tobacco*/metabolism
Plant Proteins/genetics ; Plant Proteins/metabolism ; Plants, Genetically Modified/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 9 9.

Tytuł :: Xp11 translocation renal cell carcinoma with morphological features mimicking multilocular cystic renal neoplasm of low malignant potential: a series of six cases with molecular analysis.
Autorzy :: Song Y; Pathology, West China Hospital, Sichuan University, Chengdu, China.
Yin X; Pathology, West China Hospital, Sichuan University, Chengdu, China.
Xia Q; Pathology, Nanjing Jinling Hospital, Nanjing, China.
Zheng L; Pathology, West China Hospital, Sichuan University, Chengdu, China.
Yao J; Radiology, West China Hospital, Sichuan University, Chengdu, China.
Zeng H; Urology, West China Hospital, Sichuan University, Chengdu, China.
Nie L; Pathology, West China Hospital, Sichuan University, Chengdu, China.
Gong J; Pathology, West China Hospital, Sichuan University, Chengdu, China.
Zhou Q; Pathology, West China Hospital, Sichuan University, Chengdu, China.
Chen N; Pathology, West China Hospital, Sichuan University, Chengdu, China .; Pokaż więcej
Źródło :: Journal of clinical pathology [J Clin Pathol] 2021 Mar; Vol. 74 (3), pp. 171-176. Date of Electronic Publication: 2020 Jul 22.
Typ publikacji :: Journal Article
MeSH Terms :: Gene Fusion*
Translocation, Genetic*
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/*genetics
Carcinoma, Renal Cell/*diagnostic imaging
Chromosomes, Human, X/*genetics
Kidney Neoplasms/*diagnostic imaging
Mediator Complex/*genetics
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/metabolism ; Carcinoma, Renal Cell/genetics ; Carcinoma, Renal Cell/pathology ; Female ; Gene Rearrangement ; Humans ; Kidney Neoplasms/genetics ; Kidney Neoplasms/pathology ; Male ; Mediator Complex/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 10 10.

Tytuł :: High Hepatic leukemia factor expression indicates a favorable survival in glioma patients.
Autorzy :: Liu Q; Department of Neuro-intervention, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital University, Beijing, China.
Ge H
Liu P
Li Y; Pokaż więcej
Źródło :: Medicine [Medicine (Baltimore)] 2021 Feb 12; Vol. 100 (6), pp. e23980.
Typ publikacji :: Journal Article
MeSH Terms :: Basic-Leucine Zipper Transcription Factors/*genetics
Brain Neoplasms/*pathology
Glioma/*genetics
Glioma/*mortality
Basic-Leucine Zipper Transcription Factors/pharmacology ; Case-Control Studies ; Cell Cycle ; Down-Regulation ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Neoplasm Grading/methods ; Prognosis ; Proportional Hazards Models ; Protective Factors ; Risk Factors ; Survival Analysis
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 11 11.

Tytuł :: The bZIP transcription factor TabZIP15 improves salt stress tolerance in wheat.
Autorzy :: Bi C; Key Laboratory for Crop Gene Resources and Germplasm Enhancement, MOA, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.; College of Agronomy, Xinjiang Agricultural University, Urumqi, China.
Yu Y; College of Agronomy, Xinjiang Agricultural University, Urumqi, China.
Dong C; Key Laboratory for Crop Gene Resources and Germplasm Enhancement, MOA, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Yang Y; Key Laboratory for Crop Gene Resources and Germplasm Enhancement, MOA, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Zhai Y; Key Laboratory for Crop Gene Resources and Germplasm Enhancement, MOA, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Du F; Key Laboratory for Crop Gene Resources and Germplasm Enhancement, MOA, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Xia C; Key Laboratory for Crop Gene Resources and Germplasm Enhancement, MOA, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Ni Z; College of Agronomy, Xinjiang Agricultural University, Urumqi, China.
Kong X; Key Laboratory for Crop Gene Resources and Germplasm Enhancement, MOA, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Zhang L; Key Laboratory for Crop Gene Resources and Germplasm Enhancement, MOA, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.; Pokaż więcej
Źródło :: Plant biotechnology journal [Plant Biotechnol J] 2021 Feb; Vol. 19 (2), pp. 209-211. Date of Electronic Publication: 2020 Aug 13.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Basic-Leucine Zipper Transcription Factors*/genetics
Triticum*/genetics
Triticum*/metabolism
Gene Expression Regulation, Plant ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Plants, Genetically Modified/genetics ; Plants, Genetically Modified/metabolism ; Salt Tolerance/genetics ; Stress, Physiological
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 12 12.

Tytuł :: Aminoacyl-tRNA synthetases and amino acid signaling.
Autorzy :: Yu YC; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon 21983, South Korea.
Han JM; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon 21983, South Korea; Department of Integrated OMICS for Biomedical Science, Yonsei University, Seoul 03722, South Korea. Electronic address: .
Kim S; Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon 21983, South Korea; Medicinal Bioconvergence Research Center, College of Pharmacy and College of Medicine, Gangnam Severance Hospital, Yonsei University, South Korea. Electronic address: .; Pokaż więcej
Źródło :: Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2021 Jan; Vol. 1868 (1), pp. 118889. Date of Electronic Publication: 2020 Oct 20.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :: Amino Acids/*genetics
Amino Acyl-tRNA Synthetases/*genetics
Leucine/*genetics
Leucine-tRNA Ligase/*genetics
Amino Acids/chemistry ; Amino Acyl-tRNA Synthetases/chemistry ; Humans ; Leucine/chemistry ; Leucine-tRNA Ligase/chemistry ; Protein Biosynthesis/genetics ; RNA, Transfer/genetics ; Signal Transduction/genetics
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 13 13.

Tytuł :: Leucine Dehydrogenase: Structure and Thermostability.
Autorzy :: Yamaguchi H; AJINOMOTO Co., Inc, 1-1, Suzuki-Cho, Kawasaki-Ku, Kawasaki-Shi, Kanagawa, 210-8681, Japan.
Kamegawa A; TMDU Advanced Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.
Nakata K; AJINOMOTO Co., Inc, 1-1, Suzuki-Cho, Kawasaki-Ku, Kawasaki-Shi, Kanagawa, 210-8681, Japan.
Kashiwagi T; AJINOMOTO Co., Inc, 1-1, Suzuki-Cho, Kawasaki-Ku, Kawasaki-Shi, Kanagawa, 210-8681, Japan.
Fujiyoshi Y; TMDU Advanced Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.
Tani K; Graduate School of Medicine, Mie University, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Mizukoshi T; AJINOMOTO Co., Inc, 1-1, Suzuki-Cho, Kawasaki-Ku, Kawasaki-Shi, Kanagawa, 210-8681, Japan. .; Pokaż więcej
Źródło :: Sub-cellular biochemistry [Subcell Biochem] 2021; Vol. 96, pp. 355-372.
Typ publikacji :: Journal Article; Review
MeSH Terms :: Leucine Dehydrogenase/*chemistry
Leucine Dehydrogenase/*metabolism
Bacillaceae/enzymology ; Cryoelectron Microscopy ; Enzyme Stability ; Geobacillus stearothermophilus/enzymology ; Leucine Dehydrogenase/ultrastructure ; Sporosarcina/enzymology
SCR Organism :: Lysinibacillus sphaericus; Sporosarcina psychrophila
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 14 14.

Tytuł :: Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Autorzy :: Deniston CK; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Genomics Institute of the Novartis Research Foundation, La Jolla, CA, USA.
Salogiannis J; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA.
Mathea S; Institute of Pharmaceutical Chemistry, Goethe-Universität, Frankfurt, Germany.
Snead DM; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.
Lahiri I; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Mohali, India.
Matyszewski M; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.
Donosa O; Howard Hughes Medical Institute, Chevy Chase, MD, USA.
Watanabe R; Division of Biological Sciences, Molecular Biology Section, University of California San Diego, La Jolla, CA, USA.; La Jolla Institute for Immunology, La Jolla, CA, USA.
Böhning J; Division of Biological Sciences, Molecular Biology Section, University of California San Diego, La Jolla, CA, USA.; Sir William Dunn School of Pathology, Oxford University, Oxford, UK.
Shiau AK; Small Molecule Discovery Program, Ludwig Institute for Cancer Research, La Jolla, CA, USA.; Division of Biological Sciences, Cell and Developmental Biology Section, University of California San Diego, La Jolla, CA, USA.
Knapp S; Institute of Pharmaceutical Chemistry, Goethe-Universität, Frankfurt, Germany.
Villa E; Division of Biological Sciences, Molecular Biology Section, University of California San Diego, La Jolla, CA, USA.
Reck-Peterson SL; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA. .; Howard Hughes Medical Institute, Chevy Chase, MD, USA. .; Division of Biological Sciences, Cell and Developmental Biology Section, University of California San Diego, La Jolla, CA, USA. .
Leschziner AE; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA. .; Division of Biological Sciences, Molecular Biology Section, University of California San Diego, La Jolla, CA, USA. .; Pokaż więcej
Źródło :: Nature [Nature] 2020 Dec; Vol. 588 (7837), pp. 344-349. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :: Cryoelectron Microscopy*
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/*chemistry
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/*metabolism
Microtubules/*chemistry
Microtubules/*metabolism
Parkinson Disease/*metabolism
Benzamides/pharmacology ; Biocatalysis/drug effects ; Dimerization ; Dyneins/antagonists & inhibitors ; Dyneins/metabolism ; Humans ; Kinesin/antagonists & inhibitors ; Kinesin/metabolism ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/antagonists & inhibitors ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/ultrastructure ; Microtubules/ultrastructure ; Models, Molecular ; Movement/drug effects ; Protein Binding ; Protein Domains/drug effects ; Pyrazoles/pharmacology ; WD40 Repeats
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 15 15.

Tytuł :: Circ_0123996 promotes cell proliferation and fibrosisin mouse mesangial cells through sponging miR-149-5p and inducing Bach1 expression.
Autorzy :: Wang W; Department of Nephrology, Xiangyang No.1 People's Hospital Affiliated of Hubei University of Medicine, Xiangyang, China. Electronic address: .
Feng J; Department of Nephrology, Xiangyang No.1 People's Hospital Affiliated of Hubei University of Medicine, Xiangyang, China.
Zhou H; Department of Nephrology, Xiangyang No.1 People's Hospital Affiliated of Hubei University of Medicine, Xiangyang, China.
Li Q; Department of Nephrology, The Central Hospital of Jilin City, Jilin, China.; Pokaż więcej
Źródło :: Gene [Gene] 2020 Nov 30; Vol. 761, pp. 144971. Date of Electronic Publication: 2020 Jul 22.
Typ publikacji :: Journal Article
MeSH Terms :: Basic-Leucine Zipper Transcription Factors/*biosynthesis
Basic-Leucine Zipper Transcription Factors/*metabolism
Diabetic Nephropathies/*metabolism
MicroRNAs/*metabolism
RNA, Circular/*metabolism
Adult ; Animals ; Apoptosis/physiology ; Basic-Leucine Zipper Transcription Factors/genetics ; Case-Control Studies ; Cell Line, Tumor ; Cell Movement/physiology ; Cell Proliferation/physiology ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/metabolism ; Diabetic Nephropathies/genetics ; Disease Models, Animal ; Disease Progression ; Female ; Fibrosis/genetics ; Fibrosis/metabolism ; Humans ; Male ; Mesangial Cells/metabolism ; Mice ; Mice, Inbred C57BL ; MicroRNAs/genetics ; Middle Aged ; RNA, Circular/genetics
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 16 16.

Tytuł :: Endogenous Rab29 does not impact basal or stimulated LRRK2 pathway activity.
Autorzy :: Kalogeropulou AF; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, U.K.
Freemantle JB; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, U.K.
Lis P; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, U.K.
Vides EG; Department of Biochemistry, Stanford University School of Medicine, Stanford 94305-5307, U.S.A.
Polinski NK; Michael J Fox Foundation for Parkinson's Research, Grand Central Station, PO Box 4777, New York, NY 10163, U.S.A.
Alessi DR; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, U.K.; Pokaż więcej
Źródło :: The Biochemical journal [Biochem J] 2020 Nov 27; Vol. 477 (22), pp. 4397-4423.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Signal Transduction*
Brain/*enzymology
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/*metabolism
rab GTP-Binding Proteins/*metabolism
trans-Golgi Network/*enzymology
Animals ; Humans ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/genetics ; Mice ; Mice, Knockout ; Rabbits ; rab GTP-Binding Proteins/genetics ; trans-Golgi Network/genetics
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 17 17.

Tytuł :: Specifically bound BZIP transcription factors modulate DNA supercoiling transitions.
Autorzy :: Hörberg J; Department of Chemistry and Molecular Biology, University of Gothenburg, 40530, Gothenburg, Sweden.
Reymer A; Department of Chemistry and Molecular Biology, University of Gothenburg, 40530, Gothenburg, Sweden. .; Pokaż więcej
Źródło :: Scientific reports [Sci Rep] 2020 Nov 02; Vol. 10 (1), pp. 18795. Date of Electronic Publication: 2020 Nov 02.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Basic-Leucine Zipper Transcription Factors/*chemistry
Basic-Leucine Zipper Transcription Factors/*genetics
DNA/*chemistry
DNA, Superhelical/*chemistry
Base Sequence ; Basic-Leucine Zipper Transcription Factors/physiology ; Biomechanical Phenomena ; Chromatin ; DNA/genetics ; DNA Fragmentation ; DNA, Superhelical/genetics ; Humans ; Molecular Dynamics Simulation ; Nucleic Acid Conformation
: Czasopismo naukowe

Szczegóły Pełny tekst

Skocz do pozycji: 18 18.

Tytuł :: Multicenter Study to Transplant Hepatitis C-Infected Kidneys (MYTHIC): An Open-Label Study of Combined Glecaprevir and Pibrentasvir to Treat Recipients of Transplanted Kidneys from Deceased Donors with Hepatitis C Virus Infection.
Autorzy :: Sise ME; Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Goldberg DS; Division of Digestive Health and Liver Diseases, University of Miami Miller School of Medicine, Miami, Florida.
Kort JJ; Global Medical Affairs Research and Development, AbbVie Inc., North Chicago, Illinois.
Schaubel DE; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Alloway RR; Division of Nephrology, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Durand CM; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Fontana RJ; Division of Gastroenterology and Hepatology, University of Michigan Medical School, Ann Arbor, Michigan.
Brown RS Jr; Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, New York.
Friedewald JJ; Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Prenner S; Division of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, Pennsylvania.
Landis JR; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Fernando M; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Phillips CC; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Woodle ES; Division of Transplantation, Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Rike-Shields A; Division of Transplantation, Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio.; The Christ Hospital, Cincinnati, Ohio.
Sherman KE; Division of Digestive Disease, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Elias N; Transplant Center and Division of Transplant Surgery, Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts.
Williams WW; Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Gustafson JL; Gastrointestinal Division, Department of Medicine, Liver Center, Massachusetts General Hospital, Boston, Massachusetts.
Desai NM; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Barnaba B; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Norman SP; Division of Nephrology, Michigan Medicine, Ann Arbor, Michigan.
Doshi M; Division of Nephrology, Michigan Medicine, Ann Arbor, Michigan.
Sultan ST; Division of Transplant Surgery, New York-Presbyterian/Weill Cornell Medicine, New York, New York.
Aull MJ; Division of Transplant Surgery, New York-Presbyterian/Weill Cornell Medicine, New York, New York.
Levitsky J; Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois.; Division of Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Belshe DS; Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Chung RT; Gastrointestinal Division, Department of Medicine, Liver Center, Massachusetts General Hospital, Boston, Massachusetts .
Reese PP; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.; Renal-Electrolyte and Hypertension Division, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.; Pokaż więcej
Źródło :: Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2020 Nov; Vol. 31 (11), pp. 2678-2687. Date of Electronic Publication: 2020 Aug 25.
Typ publikacji :: Clinical Trial; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :: Hepacivirus*
Kidney Transplantation*
Aminoisobutyric Acids/*therapeutic use
Antiviral Agents/*therapeutic use
Benzimidazoles/*therapeutic use
Cyclopropanes/*therapeutic use
Hepatitis C/*prevention & control
Lactams, Macrocyclic/*therapeutic use
Leucine/*analogs & derivatives
Proline/*analogs & derivatives
Quinoxalines/*therapeutic use
RNA, Viral/*blood
Sulfonamides/*therapeutic use
Adult ; Allografts/physiology ; Allografts/virology ; Aminoisobutyric Acids/adverse effects ; Antiviral Agents/adverse effects ; Benzimidazoles/adverse effects ; Cyclopropanes/adverse effects ; Drug Combinations ; Female ; Glomerular Filtration Rate ; Hepatitis C/blood ; Humans ; Kidney/physiology ; Lactams, Macrocyclic/adverse effects ; Leucine/adverse effects ; Leucine/therapeutic use ; Male ; Proline/adverse effects ; Proline/therapeutic use ; Prospective Studies ; Quinoxalines/adverse effects ; Sulfonamides/adverse effects ; Sustained Virologic Response
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 19 19.

Tytuł :: Modulation of Energy Sensing by Leucine Synergy with Natural Sirtuin Activators: Effects on Health Span.
Autorzy :: Zemel MB; NuSirt Biopharma, Research and Development, Knoxville, Tennessee, USA.; Pokaż więcej
Źródło :: Journal of medicinal food [J Med Food] 2020 Nov; Vol. 23 (11), pp. 1129-1135. Date of Electronic Publication: 2020 Aug 04.
Typ publikacji :: Journal Article; Randomized Controlled Trial
MeSH Terms :: Insulin Resistance*
Stilbenes*/pharmacology
AMP-Activated Protein Kinases/*metabolism
Leucine/*pharmacology
Resveratrol/*pharmacology
Sirtuin 1/*metabolism
Animals ; Humans ; Leucine/administration & dosage ; Longevity ; Mice, Obese ; Prediabetic State ; Resveratrol/administration & dosage
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 20 20.

Tytuł :: Duplication of leucyl-tRNA synthetase in an archaeal extremophile may play a role in adaptation to variable environmental conditions.
Autorzy :: Weitzel CS; Department of Chemistry, Illinois State University, Normal, Illinois 61761 .
Li L; Department of Biochemistry, University of Illinois, Urbana, Illinois 61801.; Center for Biophysics and Quantitative Biology, University of Illinois, Urbana, Illinois 61801.
Zhang C; Department of Microbiology, University of Illinois, Urbana, Illinois 61801.; Carl R. Woese Institute for Genomic Biology, University of Illinois, Urbana, Illinois 61801.
Eilts KK; Department of Chemistry, Illinois State University, Normal, Illinois 61761.
Bretz NM; Department of Chemistry, Illinois State University, Normal, Illinois 61761.
Gatten AL; Department of Biochemistry, University of Illinois, Urbana, Illinois 61801.
Whitaker RJ; Department of Microbiology, University of Illinois, Urbana, Illinois 61801.; Carl R. Woese Institute for Genomic Biology, University of Illinois, Urbana, Illinois 61801.
Martinis SA; Department of Biochemistry, University of Illinois, Urbana, Illinois 61801.; Center for Biophysics and Quantitative Biology, University of Illinois, Urbana, Illinois 61801.; Pokaż więcej
Źródło :: The Journal of biological chemistry [J Biol Chem] 2020 Apr 03; Vol. 295 (14), pp. 4563-4576. Date of Electronic Publication: 2020 Feb 26.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :: Archaeal Proteins/*metabolism
Leucine-tRNA Ligase/*metabolism
Sulfolobus/*enzymology
Amino Acid Sequence ; Aminoacylation ; Archaeal Proteins/chemistry ; Archaeal Proteins/classification ; Archaeal Proteins/genetics ; Catalytic Domain ; Extremophiles/metabolism ; Gene Editing ; Hydrogen-Ion Concentration ; Leucine/metabolism ; Leucine-tRNA Ligase/chemistry ; Leucine-tRNA Ligase/classification ; Leucine-tRNA Ligase/genetics ; Mutagenesis, Site-Directed ; Phylogeny ; Protein Biosynthesis ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/chemistry ; Recombinant Proteins/isolation & purification ; Sequence Alignment ; Sulfolobus/growth & development ; Temperature
: Czasopismo naukowe

Szczegóły

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