Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Ukraiński (UK)
Przejdź do strony domowej biblioteki Uniwersytet Ekonomiczny we Wrocławiu Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaUniwersytet Ekonomiczny we Wrocławiu

Wyszukujesz frazę ""Leucyl Aminopeptidase"" wg kryterium: Temat

  Lista filtrów
Wyrównaj
Wyświetlanie 1-20 z 763
Tytuł:
Expression, Characterisation, Homology Modelling and Molecular Docking of a Novel M17 Family Leucyl-Aminopeptidase from Bacillus cereus CZ.
Autorzy:
Liu J; School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Cui T; School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 03; Vol. 24 (21). Date of Electronic Publication: 2023 Nov 03.
Typ publikacji:
Journal Article
MeSH Terms:
Leucyl Aminopeptidase*
Bacillus cereus*/genetics
Bacillus cereus*/metabolism
Amino Acid Sequence ; Molecular Docking Simulation ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Peptides
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Identification of a potent and selective LAPTc inhibitor by RapidFire-Mass Spectrometry, with antichagasic activity.
Autorzy:
Izquierdo M; Centre for Protein Studies, Faculty of Biology, University of Havana, La Habana, Cuba.
Lin; Drug Discovery Unit, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, United Kingdom.
O'Neill S; Drug Discovery Unit, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, United Kingdom.
Webster LA; Drug Discovery Unit, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, United Kingdom.
Paterson C; Drug Discovery Unit, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, United Kingdom.
Thomas J; Drug Discovery Unit, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, United Kingdom.
Aguado ME; Centre for Protein Studies, Faculty of Biology, University of Havana, La Habana, Cuba.
Colina Araújo E; Department of Biochemistry, Faculty of Biology, University of Havana, La Habana, Cuba.
Alpízar-Pedraza D; Centre for Pharmaceuticals Research and Development, La Habana, Cuba.
Joji H; Drug Discovery Unit, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, United Kingdom.
MacLean L; Drug Discovery Unit, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, United Kingdom.
Hope A; Drug Discovery Unit, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, United Kingdom.
Gray DW; Drug Discovery Unit, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, United Kingdom.
Zoltner M; Wellcome Centre for Anti-Infectives Research, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, United Kingdom.; Department of Parasitology, Faculty of Science, Charles University in Prague, Biocev, Vestec, Czech Republic.
Field MC; School of Life Sciences, University of Dundee, Dundee, United Kingdom.; Biology Centre, Czech Academy of Sciences, Institute of Parasitology, České Budějovice, Czech Republic.
González-Bacerio J; Centre for Protein Studies, Faculty of Biology, University of Havana, La Habana, Cuba.; Department of Biochemistry, Faculty of Biology, University of Havana, La Habana, Cuba.
De Rycker M; Drug Discovery Unit, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, United Kingdom.
Pokaż więcej
Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Feb 15; Vol. 18 (2), pp. e0011956. Date of Electronic Publication: 2024 Feb 15 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Trypanosoma cruzi*
Chagas Disease*/drug therapy
Trypanocidal Agents*/therapeutic use
Humans ; Leucyl Aminopeptidase/chemistry ; Leucyl Aminopeptidase/pharmacology ; Leucyl Aminopeptidase/therapeutic use ; Drug Discovery ; Antiparasitic Agents/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inhibition of Insulin-Regulated Aminopeptidase by Imidazo [1,5-α]pyridines-Synthesis and Evaluation.
Autorzy:
Engen K; Department of Medicinal Chemistry, Uppsala University, BMC, P.O. Box 574, SE-751 23 Uppsala, Sweden.
Lundbäck T; Chemical Biology Consortium Sweden (CBCS), Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Division of Chemical Biology and Genome Engineering, Karolinska Institutet, Tomtebodavägen 23A, SE-171 65 Solna, Sweden.; Mechanistic & Structural Biology, Discovery Sciences, R&D, AstraZeneca, SE-431 83 Mölndal, Sweden.
Yadav A; The Beijer Laboratory, Science for Life Laboratory, Department of Medicinal Chemistry, Uppsala University, BMC, P.O. Box 574, SE-751 23 Uppsala, Sweden.
Puthiyaparambath S; The Beijer Laboratory, Science for Life Laboratory, Department of Medicinal Chemistry, Uppsala University, BMC, P.O. Box 574, SE-751 23 Uppsala, Sweden.
Rosenström U; Department of Medicinal Chemistry, Uppsala University, BMC, P.O. Box 574, SE-751 23 Uppsala, Sweden.
Gising J; The Beijer Laboratory, Science for Life Laboratory, Department of Medicinal Chemistry, Uppsala University, BMC, P.O. Box 574, SE-751 23 Uppsala, Sweden.
Jenmalm-Jensen A; Chemical Biology Consortium Sweden (CBCS), Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Division of Chemical Biology and Genome Engineering, Karolinska Institutet, Tomtebodavägen 23A, SE-171 65 Solna, Sweden.
Hallberg M; The Beijer Laboratory, Department of Pharmaceutical Biosciences, Neuropharmacology and Addiction Research, Uppsala University, BMC, P.O. Box 591, SE-751 24 Uppsala, Sweden.
Larhed M; The Beijer Laboratory, Science for Life Laboratory, Department of Medicinal Chemistry, Uppsala University, BMC, P.O. Box 574, SE-751 23 Uppsala, Sweden.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 21; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:
Journal Article
MeSH Terms:
Insulin*
Aminopeptidases*
Animals ; Insulin, Regular, Human ; CD13 Antigens ; Leucyl Aminopeptidase ; Pyridines
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synthetic and biological surfactant effects on freshwater biofilm community composition and metabolic activity.
Autorzy:
Gill SP; Department of Geography and Environmental Studies, Ulster University, Coleraine, BT52 1SA, N. Ireland, UK. .
Hunter WR; Fisheries and Aquatic Ecosystems Branch, Agri-Food and Biosciences Institute, Belfast, N. Ireland, UK.
Coulson LE; WasserCluster Lunz, Lunz am See, Austria.; Institute of Hydrobiology and Aquatic Ecosystem Management, University of Natural Resources and Life Sciences, Vienna, Austria.
Banat IM; School of Biomedical Sciences, Ulster University, Coleraine, N. Ireland, UK.
Schelker J; WasserCluster Lunz, Lunz am See, Austria.; Department of Functional and Evolutionary Ecology, University of Vienna, Vienna, Austria.
Pokaż więcej
Źródło:
Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2022 Oct; Vol. 106 (19-20), pp. 6847-6859. Date of Electronic Publication: 2022 Sep 19.
Typ publikacji:
Journal Article
MeSH Terms:
Leucyl Aminopeptidase*/metabolism
Leucyl Aminopeptidase*/pharmacology
Surface-Active Agents*/pharmacology
Biofilms ; Ecosystem ; Fresh Water/chemistry ; Glucosidases/pharmacology ; Sodium Dodecyl Sulfate ; Water/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Biochemical and cellular characterisation of the Plasmodium falciparum M1 alanyl aminopeptidase (PfM1AAP) and M17 leucyl aminopeptidase (PfM17LAP).
Autorzy:
Mathew R; Institute of Parasitology, McGill University, 21111 Lakeshore Road, Sainte-Anne-de-Bellevue, Québec, H9X 3V9, Canada.; School of Biological Sciences, Queen's University Belfast, Belfast, Northern Ireland, UK.
Wunderlich J; Institute of Parasitology, McGill University, 21111 Lakeshore Road, Sainte-Anne-de-Bellevue, Québec, H9X 3V9, Canada.; European Molecular Biology Laboratory, Notkestraße 85, 22607, Hamburg, Germany.
Thivierge K; Institute of Parasitology, McGill University, 21111 Lakeshore Road, Sainte-Anne-de-Bellevue, Québec, H9X 3V9, Canada.; Laboratoire de Santé Publique du Québec, Institut National de Santé Publique du Québec, Sainte-Anne-de-Bellevue, QC, Canada.
Cwiklinski K; School of Biological Sciences, Queen's University Belfast, Belfast, Northern Ireland, UK.; Centre for One Health & Ryan Institute, School of Natural Sciences, NUI Galway, Galway, Republic of Ireland.
Dumont C; Department of Biochemistry and Molecular Biology, Bio21 Institute, University of Melbourne, Melbourne, VIC, Australia.
Tilley L; Department of Biochemistry and Molecular Biology, Bio21 Institute, University of Melbourne, Melbourne, VIC, Australia.
Rohrbach P; Institute of Parasitology, McGill University, 21111 Lakeshore Road, Sainte-Anne-de-Bellevue, Québec, H9X 3V9, Canada.
Dalton JP; Institute of Parasitology, McGill University, 21111 Lakeshore Road, Sainte-Anne-de-Bellevue, Québec, H9X 3V9, Canada. .; School of Biological Sciences, Queen's University Belfast, Belfast, Northern Ireland, UK. .; Centre for One Health & Ryan Institute, School of Natural Sciences, NUI Galway, Galway, Republic of Ireland. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2021 Feb 03; Vol. 11 (1), pp. 2854. Date of Electronic Publication: 2021 Feb 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD13 Antigens/*metabolism
Leucyl Aminopeptidase/*metabolism
Plasmodium falciparum/*enzymology
Protozoan Proteins/*metabolism
Animals ; Antimalarials/pharmacology ; Antimalarials/therapeutic use ; CD13 Antigens/antagonists & inhibitors ; CD13 Antigens/chemistry ; CD13 Antigens/isolation & purification ; Cell Fractionation ; Cells, Cultured ; Cytosol/enzymology ; Drug Development ; Enzyme Assays ; Erythrocytes/parasitology ; Humans ; Hydrogen-Ion Concentration ; Leucyl Aminopeptidase/antagonists & inhibitors ; Leucyl Aminopeptidase/chemistry ; Leucyl Aminopeptidase/isolation & purification ; Malaria, Falciparum/drug therapy ; Malaria, Falciparum/parasitology ; Plasmodium falciparum/drug effects ; Protozoan Proteins/antagonists & inhibitors ; Protozoan Proteins/chemistry ; Protozoan Proteins/isolation & purification ; Rabbits ; Recombinant Proteins/chemistry ; Recombinant Proteins/isolation & purification
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In Silico Screening for Novel Leucine Aminopeptidase Inhibitors with 3,4-Dihydroisoquinoline Scaffold.
Autorzy:
Ziemska J; National Institute of Public Health-National Institute of Hygiene, Chocimska 24, 00-791 Warsaw, Poland.
Solecka J; National Institute of Public Health-National Institute of Hygiene, Chocimska 24, 00-791 Warsaw, Poland.
Jarończyk M; National Medicines Institute, Chełmska 30/34, 00-725 Warsaw, Poland.
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2020 Apr 10; Vol. 25 (7). Date of Electronic Publication: 2020 Apr 10.
Typ publikacji:
Journal Article
MeSH Terms:
Models, Molecular*
Quantitative Structure-Activity Relationship*
Isoquinolines/*chemistry
Leucyl Aminopeptidase/*chemistry
Protease Inhibitors/*chemistry
Drug Design ; Humans ; Leucyl Aminopeptidase/antagonists & inhibitors ; Molecular Conformation ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Molecular Structure ; Protease Inhibitors/pharmacology ; Reproducibility of Results
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
LAP3 contributes to IFN-γ-induced arginine depletion and malignant transformation of bovine mammary epithelial cells.
Autorzy:
Li L; Department of First Hospital, Jilin University, Xinmin Street 1, Changchun, China.
Li F; State Key Laboratory for Zoonotic Diseases, College of Veterinary Medicine, Jilin University, Xi'an Road 5333, Changchun, China.
Hu X; Department of First Hospital, Jilin University, Xinmin Street 1, Changchun, China.; Shannan Hospital, Shannan, China.
Wu Z; State Key Laboratory for Zoonotic Diseases, College of Veterinary Medicine, Jilin University, Xi'an Road 5333, Changchun, China.
Ren W; Department of First Hospital, Jilin University, Xinmin Street 1, Changchun, China.
Wang T; Department of First Hospital, Jilin University, Xinmin Street 1, Changchun, China.
Ji Z; Department of First Hospital, Jilin University, Xinmin Street 1, Changchun, China.
Li N; State Key Laboratory for Zoonotic Diseases, College of Veterinary Medicine, Jilin University, Xi'an Road 5333, Changchun, China.
Gu J; State Key Laboratory for Zoonotic Diseases, College of Veterinary Medicine, Jilin University, Xi'an Road 5333, Changchun, China.
Sun C; State Key Laboratory for Zoonotic Diseases, College of Veterinary Medicine, Jilin University, Xi'an Road 5333, Changchun, China.
Feng X; State Key Laboratory for Zoonotic Diseases, College of Veterinary Medicine, Jilin University, Xi'an Road 5333, Changchun, China.
Han W; State Key Laboratory for Zoonotic Diseases, College of Veterinary Medicine, Jilin University, Xi'an Road 5333, Changchun, China.
Huang J; Department of First Hospital, Jilin University, Xinmin Street 1, Changchun, China. .
Lei L; State Key Laboratory for Zoonotic Diseases, College of Veterinary Medicine, Jilin University, Xi'an Road 5333, Changchun, China. .
Pokaż więcej
Źródło:
BMC cancer [BMC Cancer] 2022 Aug 08; Vol. 22 (1), pp. 864. Date of Electronic Publication: 2022 Aug 08.
Typ publikacji:
Journal Article
MeSH Terms:
Arginine*/metabolism
Breast Neoplasms*/metabolism
Leucyl Aminopeptidase/*metabolism
Animals ; Argininosuccinate Synthase/metabolism ; Breast/metabolism ; Cattle ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/metabolism ; Epithelial Cells/metabolism ; Female ; Humans ; Interferon-gamma/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Sperm-Leucylaminopeptidases are required for male fertility as structural components of mitochondrial paracrystalline material in Drosophila melanogaster sperm.
Autorzy:
Laurinyecz B; Department of Genetics, University of Szeged, Szeged, Hungary.
Vedelek V; Department of Genetics, University of Szeged, Szeged, Hungary.
Kovács AL; Department of Anatomy, Eötvös Loránd University, Budapest, Hungary.
Szilasi K; Department of Genetics, University of Szeged, Szeged, Hungary.
Lipinszki Z; Institute of Biochemistry and MTA SZBK Lendület Laboratory of Cell Cycle Regulation, Biological Research Centre, Hungarian Academy of Sciences, Szeged, Hungary.
Slezák C; Department of Genetics, University of Szeged, Szeged, Hungary.
Darula Z; Laboratory of Proteomics Research, Biological Research Centre, Hungarian Academy of Sciences, Szeged, Hungary.
Juhász G; Department of Anatomy, Eötvös Loránd University, Budapest, Hungary.
Sinka R; Department of Genetics, University of Szeged, Szeged, Hungary.
Pokaż więcej
Źródło:
PLoS genetics [PLoS Genet] 2019 Feb 25; Vol. 15 (2), pp. e1007987. Date of Electronic Publication: 2019 Feb 25 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Drosophila Proteins/*metabolism
Drosophila melanogaster/*enzymology
Leucyl Aminopeptidase/*metabolism
Spermatozoa/*enzymology
Animals ; Animals, Genetically Modified ; Crystallization ; Drosophila Proteins/chemistry ; Drosophila Proteins/genetics ; Drosophila melanogaster/genetics ; Drosophila melanogaster/physiology ; Fertility/genetics ; Fertility/physiology ; Genes, Insect ; Infertility, Male/enzymology ; Infertility, Male/genetics ; Leucyl Aminopeptidase/chemistry ; Leucyl Aminopeptidase/genetics ; Male ; Microscopy, Electron, Transmission ; Mitochondria/chemistry ; Mitochondria/enzymology ; Mitochondria/ultrastructure ; Mutation ; RNA Interference ; Spermatogenesis/genetics ; Spermatogenesis/physiology ; Spermatozoa/physiology ; Spermatozoa/ultrastructure
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A new method to evaluate the enzyme-suppressing activity of a leucine aminopeptidase 3 inhibitor.
Autorzy:
Wu H; School of Pharmacy, Weifang Medical University.
Jiang W; School of Pharmacy, Weifang Medical University.
Li B; Weifang Municipal Hospital.
Yang H; School of Pharmacy, Weifang Medical University.
Zhao X; School of Pharmacy, Weifang Medical University.
Zhang H; School of Pharmacy, Weifang Medical University.
Wang S; School of Pharmacy, Weifang Medical University.
Peng L; School of Pharmacy, Weifang Medical University.
Wang L; Molecular Oncology Laboratory, Weifang Medical University.
Wang X; School of Pharmacy, Weifang Medical University.
Dai G; School of Pharmacy, Weifang Medical University.
Fang C; School of Pharmacy, Weifang Medical University.
Pokaż więcej
Źródło:
Drug discoveries & therapeutics [Drug Discov Ther] 2019; Vol. 13 (1), pp. 17-21.
Typ publikacji:
Journal Article
MeSH Terms:
Leucine/*analogs & derivatives
Leucyl Aminopeptidase/*antagonists & inhibitors
Leucyl Aminopeptidase/*biosynthesis
Protease Inhibitors/*pharmacology
A549 Cells ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/pharmacology ; Humans ; K562 Cells ; Lentivirus/genetics ; Lentivirus/metabolism ; Leucine/pharmacology ; Leucyl Aminopeptidase/genetics ; MCF-7 Cells
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Characterization and heterologous expression of a novel Co -dependent leucyl aminopeptidase Amp0279 originating from Lysinibacillus sphaericus.
Autorzy:
Zhao P; College of Life Science, South-Central University for Nationalities, Wuhan, 430074, China.
Zhang M; College of Life Science, South-Central University for Nationalities, Wuhan, 430074, China.
Wan X; Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.
Geng P; College of Life Science, South-Central University for Nationalities, Wuhan, 430074, China.
Xiong H; College of Life Science, South-Central University for Nationalities, Wuhan, 430074, China. .
Hu X; College of Life Science, South-Central University for Nationalities, Wuhan, 430074, China. .
Pokaż więcej
Źródło:
Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2022 Feb; Vol. 106 (3), pp. 1139-1149. Date of Electronic Publication: 2022 Jan 21.
Typ publikacji:
Journal Article
MeSH Terms:
Bacillaceae*/genetics
Bacillus*
Leucyl Aminopeptidase ; Phylogeny
SCR Organism:
Lysinibacillus sphaericus
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Expression, Tissue Localization and Serodiagnostic Potential of Echinococcus granulosus Leucine Aminopeptidase.
Autorzy:
Wu M; Department of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. .
Yan M; Department of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. .
Xu J; Department of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. .
Liang Y; Department of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. .
Gu X; Department of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. .
Xie Y; Department of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. .
Jing B; Department of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. .
Lai W; Department of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. .
Peng X; Department of Chemistry, College of Life and Basic Science, Sichuan Agricultural University, Ya'an 625014, China. .
Yang G; Department of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. .
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2018 Apr 03; Vol. 19 (4). Date of Electronic Publication: 2018 Apr 03.
Typ publikacji:
Journal Article
MeSH Terms:
Echinococcosis/*blood
Echinococcus granulosus/*enzymology
Leucyl Aminopeptidase/*metabolism
Animals ; Antibodies/blood ; Antibodies, Helminth/blood ; Echinococcus granulosus/immunology ; Leucyl Aminopeptidase/genetics ; Leucyl Aminopeptidase/immunology ; Rabbits ; Serologic Tests ; Sheep
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The aminopeptidase inhibitor, z-L-CMK, is toxic and induces cell death in Jurkat T cells through oxidative stress.
Autorzy:
Yeo EH; a School of Science , Monash University Malaysia , Bandar Sunway , Malaysia.
Goh WL; a School of Science , Monash University Malaysia , Bandar Sunway , Malaysia.
Chow SC; a School of Science , Monash University Malaysia , Bandar Sunway , Malaysia.
Pokaż więcej
Źródło:
Toxicology mechanisms and methods [Toxicol Mech Methods] 2018 Mar; Vol. 28 (3), pp. 157-166. Date of Electronic Publication: 2017 Sep 11.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Amino Acid Chloromethyl Ketones/*toxicity
Apoptosis/*drug effects
Leucyl Aminopeptidase/*antagonists & inhibitors
Necrosis/*chemically induced
Oxidative Stress/*drug effects
Protease Inhibitors/*toxicity
T-Lymphocytes/*drug effects
Amino Acid Chloromethyl Ketones/antagonists & inhibitors ; Biomarkers/metabolism ; Caspase Inhibitors/pharmacology ; Caspases/chemistry ; Caspases/metabolism ; Cell Nucleus Shape/drug effects ; Cell Survival/drug effects ; Glutathione/antagonists & inhibitors ; Glutathione/metabolism ; Humans ; Jurkat Cells ; Leucyl Aminopeptidase/metabolism ; Membrane Potential, Mitochondrial/drug effects ; Nucleosomes/drug effects ; Nucleosomes/immunology ; Nucleosomes/metabolism ; Osmolar Concentration ; Peptide Fragments/metabolism ; Protease Inhibitors/chemistry ; Proteolysis/drug effects ; T-Lymphocytes/cytology ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synthesis, Characterization and In Vitro Evaluation of a Novel Glycol Chitosan-EDTA Conjugate to Inhibit Aminopeptidase-Mediated Degradation of Thymopoietin Oligopeptides.
Autorzy:
Feng J; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun 130012, China. .
Chen Y; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun 130012, China. chen_.; Key Laboratory for Molecular Enzymology and Engineering the Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China. chen_.
Li F; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun 130012, China. .
Cui L; Institute of Pharmaceutical Science, King's college London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, UK. .
Shi N; Key Laboratory for Molecular Enzymology and Engineering the Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China. .; Department of Pharmaceutics, School of Pharmacy, Jilin Medical University, Jilin 132013, China. .
Kong W; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun 130012, China. .; Key Laboratory for Molecular Enzymology and Engineering the Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China. .
Zhang Y; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun 130012, China. .; Key Laboratory for Molecular Enzymology and Engineering the Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China. .
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2017 Jul 26; Vol. 22 (8). Date of Electronic Publication: 2017 Jul 26.
Typ publikacji:
Evaluation Study; Journal Article
MeSH Terms:
Chitosan/*chemistry
Edetic Acid/*analogs & derivatives
Leucyl Aminopeptidase/*antagonists & inhibitors
Oligopeptides/*metabolism
Thymopoietins/*metabolism
Animals ; Cell Survival ; Chelating Agents/chemistry ; Cobalt/chemistry ; Dogs ; Edetic Acid/chemistry ; Fluoresceins/metabolism ; Ions/chemistry ; Leucyl Aminopeptidase/metabolism ; Madin Darby Canine Kidney Cells ; Proteolysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Structural insights into chaperone-activity enhancement by a K354E mutation in tomato acidic leucine aminopeptidase.
Autorzy:
DuPrez KT; Department of Biochemistry, University of California Riverside, Riverside, CA 92521, USA.
Scranton MA; Department of Botany and Plant Sciences and Center for Plant Cell Biology, University of California Riverside, Riverside, CA 92521, USA.
Walling LL; Department of Botany and Plant Sciences and Center for Plant Cell Biology, University of California Riverside, Riverside, CA 92521, USA.
Fan L; Department of Biochemistry, University of California Riverside, Riverside, CA 92521, USA.
Pokaż więcej
Źródło:
Acta crystallographica. Section D, Structural biology [Acta Crystallogr D Struct Biol] 2016 May; Vol. 72 (Pt 5), pp. 694-702. Date of Electronic Publication: 2016 Apr 26.
Typ publikacji:
Journal Article
MeSH Terms:
Point Mutation*
Leucyl Aminopeptidase/*chemistry
Leucyl Aminopeptidase/*genetics
Solanum lycopersicum/*enzymology
Solanum lycopersicum/*genetics
Catalytic Domain ; Enzyme Stability ; Leucyl Aminopeptidase/metabolism ; Solanum lycopersicum/chemistry ; Solanum lycopersicum/metabolism ; Models, Molecular ; Protein Conformation ; Protein Multimerization
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Phosphinotripeptidic Inhibitors of Leucylaminopeptidases.
Autorzy:
Jewgiński M; Department of Bioorganic Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.
Haremza K; Department of Bioorganic Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.
de Los Santos JM; Department of Organic Chemistry I, Faculty of Pharmacy, Lascaray Research Center, University of the Basque Country (UPV/EHU), Paseo de la Universidad, 7, 01006 Vitoria, Spain.
Es Sbai Z; Department of Organic Chemistry I, Faculty of Pharmacy, Lascaray Research Center, University of the Basque Country (UPV/EHU), Paseo de la Universidad, 7, 01006 Vitoria, Spain.
Oszywa B; Institute of Chemistry, University of Opole, Oleska 48, 45-052 Opole, Poland.
Pawełczak M; Institute of Chemistry, University of Opole, Oleska 48, 45-052 Opole, Poland.
Palacios F; Department of Organic Chemistry I, Faculty of Pharmacy, Lascaray Research Center, University of the Basque Country (UPV/EHU), Paseo de la Universidad, 7, 01006 Vitoria, Spain.
Latajka R; Department of Bioorganic Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 May 11; Vol. 22 (10). Date of Electronic Publication: 2021 May 11.
Typ publikacji:
Journal Article
MeSH Terms:
Enzyme Inhibitors/*pharmacology
Leucyl Aminopeptidase/*antagonists & inhibitors
Peptide Fragments/*pharmacology
Phosphines/*chemistry
Animals ; Enzyme Inhibitors/chemistry ; Models, Molecular ; Peptide Fragments/chemistry ; Protein Conformation ; Swine
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Fruit ripening-associated leucylaminopeptidase with cysteinylglycine dipeptidase activity from durian suggests its involvement in glutathione recycling.
Autorzy:
Panpetch P; Molecular Crop Research Unit, Department of Biochemistry, Faculty of Science, Chulalongkorn University, 254 Phayathai Road, Bangkok, 10330, Thailand.
Sirikantaramas S; Molecular Crop Research Unit, Department of Biochemistry, Faculty of Science, Chulalongkorn University, 254 Phayathai Road, Bangkok, 10330, Thailand. .; Omics Sciences and Bioinformatics Centre, Chulalongkorn University, 254 Phayathai Road, Bangkok, 10330, Thailand. .
Pokaż więcej
Źródło:
BMC plant biology [BMC Plant Biol] 2021 Feb 01; Vol. 21 (1), pp. 69. Date of Electronic Publication: 2021 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Bombacaceae/*enzymology
Bombacaceae/*growth & development
Dipeptidases/*metabolism
Fruit/*enzymology
Fruit/*growth & development
Glutathione/*metabolism
Leucyl Aminopeptidase/*metabolism
Base Sequence ; Bombacaceae/genetics ; Gene Expression Regulation, Plant ; Green Fluorescent Proteins/metabolism ; Models, Biological ; Phylogeny ; Plant Proteins/metabolism ; Subcellular Fractions/metabolism ; Nicotiana/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 763

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies