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Tytuł :
[Clinical characteristics and prognosis of MLL-AF6 positive patients with acute myeloid leukemia].
Autorzy :
Zhang MX; Department of Hematology, Peking University International Hospital, Beijing 102206, China.
Shi WZ; Heping Hospital Affiliated to Changzhi Medical College, Changzhi 046000, Shanxi, China.
Liu JX; Department of Hematology, Peking University International Hospital, Beijing 102206, China.
Wang CJ; Department of Hematology, Peking University International Hospital, Beijing 102206, China.
Li Y; Department of Hematology, Peking University International Hospital, Beijing 102206, China.
Wang W; Department of Hematology, Peking University International Hospital, Beijing 102206, China.
Jiang B; Department of Hematology, Peking University International Hospital, Beijing 102206, China.
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Źródło :
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences [Beijing Da Xue Xue Bao Yi Xue Ban] 2021 Oct 18; Vol. 53 (5), pp. 915-920.
Typ publikacji :
Journal Article
MeSH Terms :
Hematopoietic Stem Cell Transplantation*
Leukemia, Myeloid, Acute*/diagnosis
Leukemia, Myeloid, Acute*/genetics
Adult ; Female ; Humans ; Male ; Myeloid-Lymphoid Leukemia Protein/genetics ; Oncogene Proteins, Fusion/genetics ; Prognosis ; Remission Induction ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Engineered type 1 regulatory T cells designed for clinical use kill primary pediatric acute myeloid leukemia cells.
Autorzy :
Cieniewicz B; Department of Pediatrics, Division of Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford.
Uyeda MJ; Department of Pediatrics, Division of Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford, CA; Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford.
Chen PP; Department of Pediatrics, Division of Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford.
Sayitoglu EC; Department of Pediatrics, Division of Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford.
Liu JM; Department of Pediatrics, Division of Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford.
Andolfi G; San Raffaele Telethon Institute for Gene Therapy, Milan.
Greenthal K; Department of Pediatrics, Division of Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford.
Bertaina A; Department of Pediatrics, Division of Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford.
Gregori S; San Raffaele Telethon Institute for Gene Therapy, Milan.
Bacchetta R; Department of Pediatrics, Division of Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford.
Lacayo NJ; Department of Pediatrics, Division of Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford.
Cepika AM; Department of Pediatrics, Division of Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford.
Roncarolo MG; Department of Pediatrics, Division of Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford, CA; Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford. .
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Źródło :
Haematologica [Haematologica] 2021 Oct 01; Vol. 106 (10), pp. 2588-2597. Date of Electronic Publication: 2021 Oct 01.
Typ publikacji :
Journal Article
MeSH Terms :
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/therapy
T-Lymphocytes, Regulatory*
Adult ; CD4-Positive T-Lymphocytes ; Child ; Graft vs Leukemia Effect ; Humans ; Translocation, Genetic
Czasopismo naukowe
Tytuł :
The molecular and serological investigation of Feline immunodeficiency virus and Feline leukemia virus in stray cats of Western Turkey.
Autorzy :
Muz D; Department of Virology, Tekirdag Namik Kemal University, Faculty of Veterinary Medicine, Tekirdag 59030, Turkey. Electronic address: .
Can H; Department of Molecular Biology, Ege University Faculty of Sciences, Bornova, Izmir, 35100, Turkey.
Karakavuk M; Department of Parasitology, Ege University Medical School, Bornova, Izmir, 35100, Turkey; Odemiş Training Collage, Ege University, Odemiş, İzmir, 35400, Turkey.
Döşkaya M; Department of Parasitology, Ege University Medical School, Bornova, Izmir, 35100, Turkey.
Özdemir HG; The Protection and Development Union of Izmir Bird Paradise, Izmir, Turkey.
Değirmenci Döşkaya A; Department of Parasitology, Ege University Medical School, Bornova, Izmir, 35100, Turkey.
Atalay Şahar E; Department of Molecular Biology, Ege University Faculty of Sciences, Bornova, Izmir, 35100, Turkey.
Pektaş B; Izmir Atatürk Training and Research Hospital, Department of Microbiology, Yeşilyurt, Izmir, Turkey.
Karakuş M; Department of Medical Microbiology, Hamidiye Faculty of Medicine, University of Health Sciences, İstanbul, Turkey.
Töz S; Department of Parasitology, Ege University Medical School, Bornova, Izmir, 35100, Turkey.
Özbel Y; Department of Parasitology, Ege University Medical School, Bornova, Izmir, 35100, Turkey.
Gürüz AY; Department of Parasitology, Ege University Medical School, Bornova, Izmir, 35100, Turkey.
Muz MN; Department of Parasitology, Tekirdag Namik Kemal University, Faculty of Veterinary Medicine, Tekirdag 59030, Turkey.
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Źródło :
Comparative immunology, microbiology and infectious diseases [Comp Immunol Microbiol Infect Dis] 2021 Oct; Vol. 78, pp. 101688. Date of Electronic Publication: 2021 Jun 29.
Typ publikacji :
Journal Article
MeSH Terms :
Cat Diseases*/epidemiology
Feline Acquired Immunodeficiency Syndrome*/epidemiology
Immunodeficiency Virus, Feline*/genetics
Leukemia, Feline*/epidemiology
Animals ; Cats ; Leukemia Virus, Feline/genetics ; Phylogeny ; Turkey/epidemiology
Czasopismo naukowe
Tytuł :
[The Effect and Mechanism of Novel Telomerase Inhibitor Nilo 22 on Leukemia Cells].
Autorzy :
Yin JJ; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Disease Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Tang Q; High-throughput Molecular Drug Discovery Center, Tianjin International Joint Academy of Biomedicine, Tianjin 300457, China.
Gu JL; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Disease Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Li YF; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Disease Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Gao HE; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Disease Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China,Department of Pharmacy, Tianjin First Central Hospital, School of Medicine, Nankai University, Tianjin 300192, China.
He M; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Disease Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Yang M; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Disease Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Zhang WS; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Disease Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Xu H; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Disease Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Wang CQ; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Disease Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Li YH; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Disease Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Bai CG; High-throughput Molecular Drug Discovery Center, Tianjin International Joint Academy of Biomedicine, Tianjin 300457, China,E-mail: .
Gao YD; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Disease Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China,E-mail: .
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Źródło :
Zhongguo shi yan xue ye xue za zhi [Zhongguo Shi Yan Xue Ye Xue Za Zhi] 2021 Aug; Vol. 29 (4), pp. 1056-1064.
Typ publikacji :
Journal Article
MeSH Terms :
Leukemia*
Telomerase/*antagonists & inhibitors
Animals ; Apoptosis/drug effects ; Cell Cycle/drug effects ; Cell Line, Tumor ; Humans ; Mice ; Myeloid-Lymphoid Leukemia Protein/genetics ; Telomerase/metabolism ; Telomere/metabolism
Czasopismo naukowe
Tytuł :
Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia: Who, When, and How?
Autorzy :
Loke J; Centre for Clinical Haematology, Queen Elizabeth Hospital, Birmingham, United Kingdom.; CRUK Clinical Trials Unit, University of Birmingham, Birmingham, United Kingdom.
Buka R; Centre for Clinical Haematology, Queen Elizabeth Hospital, Birmingham, United Kingdom.; CRUK Clinical Trials Unit, University of Birmingham, Birmingham, United Kingdom.
Craddock C; Centre for Clinical Haematology, Queen Elizabeth Hospital, Birmingham, United Kingdom.; CRUK Clinical Trials Unit, University of Birmingham, Birmingham, United Kingdom.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 May 03; Vol. 12, pp. 659595. Date of Electronic Publication: 2021 May 03 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Graft vs Leukemia Effect*
Hematopoietic Stem Cell Transplantation/*methods
Leukemia, Myeloid/*therapy
Transplantation Conditioning/*methods
Acute Disease ; Adult ; Disease-Free Survival ; Humans ; Leukemia, Myeloid/pathology ; Remission Induction ; Transplantation, Homologous
Czasopismo naukowe
Tytuł :
Prognostic value of minimal residual disease measured by fusion-gene transcript in infants with KMT2A-rearranged acute lymphoblastic leukaemia treated according to the MLL-Baby protocol.
Autorzy :
Tsaur G; Regional Children's Hospital, Ekaterinburg, Russian Federation.; Research Institute of Medical Cell Technologies, Ekaterinburg, Russian Federation.; Ural State Medical University, Ekaterinburg, Russian Federation.
Popov A; National Research and Clinical Center for Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation.
Riger T; Regional Children's Hospital, Ekaterinburg, Russian Federation.; Research Institute of Medical Cell Technologies, Ekaterinburg, Russian Federation.
Kustanovich A; The Sharett Institute of Oncology, Hadassah Medical Center, Jerusalem, Israel.
Solodovnikov A; Research Institute of Medical Cell Technologies, Ekaterinburg, Russian Federation.; Ural State Medical University, Ekaterinburg, Russian Federation.
Shorikov E; PET-Technology Center of Nuclear Medicine, Ekaterinburg, Russian Federation.
Demina A; Regional Children's Hospital, Ekaterinburg, Russian Federation.; Research Institute of Medical Cell Technologies, Ekaterinburg, Russian Federation.
Verzhbitskaya T; Regional Children's Hospital, Ekaterinburg, Russian Federation.; Research Institute of Medical Cell Technologies, Ekaterinburg, Russian Federation.
Streneva O; Regional Children's Hospital, Ekaterinburg, Russian Federation.; Research Institute of Medical Cell Technologies, Ekaterinburg, Russian Federation.
Makarova O; Regional Children's Hospital, Ekaterinburg, Russian Federation.
Lapotentova E; Belarussian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Aleinikova O; Belarussian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Miakova N; National Research and Clinical Center for Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation.
Boichenko E; City Children's Hospital, 1, Saint-Petersburg, Russian Federation.
Kondratchik K; Morozov Children's Hospital, Moscow, Russian Federation.
Ponomareva N; Republican Children's Hospital, Moscow, Russian Federation.
Karachunskiy A; National Research and Clinical Center for Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation.
Roumiantsev A; National Research and Clinical Center for Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation.
Fechina L; Regional Children's Hospital, Ekaterinburg, Russian Federation.; Research Institute of Medical Cell Technologies, Ekaterinburg, Russian Federation.
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Źródło :
British journal of haematology [Br J Haematol] 2021 Jun; Vol. 193 (6), pp. 1151-1156. Date of Electronic Publication: 2021 Feb 14.
Typ publikacji :
Clinical Trial; Journal Article; Multicenter Study
MeSH Terms :
Histone-Lysine N-Methyltransferase*/blood
Histone-Lysine N-Methyltransferase*/genetics
Myeloid-Lymphoid Leukemia Protein*/blood
Myeloid-Lymphoid Leukemia Protein*/genetics
Oncogene Proteins, Fusion*/blood
Oncogene Proteins, Fusion*/genetics
Antineoplastic Combined Chemotherapy Protocols/*administration & dosage
Disease-Free Survival ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Neoplasm, Residual ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/blood ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/mortality ; Survival Rate
Czasopismo naukowe
Tytuł :
[Therapy-Related Acute Myeloid Leukemia with 11q23 Abnormality That Developed after Chemotherapy for Colorectal Cancer].
Autorzy :
Saito M; Dept. of Internal Medicine and Hematology/Blood Disorders Center, Aiiku Hospital.
Miyajima T
Ogasawara R
Yokoyama E
Izumiyama K
Mori A
Morioka M
Kondo T
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Źródło :
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2021 Jul; Vol. 48 (7), pp. 971-974.
Typ publikacji :
Journal Article
MeSH Terms :
Colorectal Neoplasms*/drug therapy
Leukemia, Myeloid, Acute*/chemically induced
Leukemia, Myeloid, Acute*/drug therapy
Aged ; Chromosome Aberrations ; Histone-Lysine N-Methyltransferase ; Humans ; Myeloid-Lymphoid Leukemia Protein/genetics
Czasopismo naukowe
Tytuł :
[Analysis of fusion gene expression in acute myeloid leukemia].
Autorzy :
Yan Q; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Lin YN; SINO-US Diagnostics Lab, Tianjin 300385, China.
Huang XQ; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Qian LZ; SINO-US Diagnostics Lab, Tianjin 300385, China.
Ma JT; SINO-US Diagnostics Lab, Tianjin 300385, China.
Zhang H; SINO-US Diagnostics Lab, Tianjin 300385, China.
Chen L; SINO-US Diagnostics Lab, Tianjin 300385, China.
Chen XJ; SINO-US Diagnostics Lab, Tianjin 300385, China.
Mi YC; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Ru K; SINO-US Diagnostics Lab, Tianjin 300385, China.
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Źródło :
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi [Zhonghua Xue Ye Xue Za Zhi] 2021 Jun 14; Vol. 42 (6), pp. 480-486.
Typ publikacji :
Journal Article
MeSH Terms :
Leukemia, Myeloid, Acute*/genetics
Adult ; Child ; Gene Expression ; Humans ; Immunophenotyping ; Mutation ; Myeloid-Lymphoid Leukemia Protein/genetics ; Retrospective Studies
Czasopismo naukowe
Tytuł :
P2X7 promotes the progression of MLL-AF9 induced acute myeloid leukemia by upregulation of Pbx3.
Autorzy :
Feng W; Institute of Hematology and Blood Diseases Hospital, Peking Union Medical College, China.
Yang X; Institute of Hematology and Blood Diseases Hospital, Peking Union Medical College, China.
Wang L; Institute of Hematology and Blood Diseases Hospital, Peking Union Medical College, China.
Wang R; Institute of Hematology and Blood Diseases Hospital, Peking Union Medical College, China.
Yang F; Institute of Hematology and Blood Diseases Hospital, Peking Union Medical College, China.
Wang H; Institute of Hematology and Blood Diseases Hospital, Peking Union Medical College, China.
Liu X; Institute of Hematology and Blood Diseases Hospital, Peking Union Medical College, China.
Ren Q; Institute of Hematology and Blood Diseases Hospital, Peking Union Medical College, China.
Zhang Y; Institute of Hematology and Blood Diseases Hospital, Peking Union Medical College, China.
Zhu X; Institute of Hematology and Blood Diseases Hospital, Peking Union Medical College, China.
Zheng G; Institute of Hematology and Blood Diseases Hospital, Peking Union Medical College, China.
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Źródło :
Haematologica [Haematologica] 2021 May 01; Vol. 106 (5), pp. 1278-1289. Date of Electronic Publication: 2021 May 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Leukemic*
Leukemia, Myeloid, Acute*/genetics
Oncogene Proteins, Fusion*/genetics
Receptors, Purinergic P2X7*
Animals ; Mice ; Myeloid-Lymphoid Leukemia Protein/genetics ; Myeloid-Lymphoid Leukemia Protein/metabolism ; Signal Transduction ; Transcriptional Activation ; Up-Regulation
Czasopismo naukowe
Tytuł :
Oncorequisite role of an aldehyde dehydrogenase in the pathogenesis of T-cell acute lymphoblastic leukemia.
Autorzy :
Zhang C; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
Amanda S; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
Wang C; Department of Anatomy, National University of Singapore, Singapore.
King Tan T; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
Zulfaqar Ali M; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
Zhong Leong W; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
Moy Ng L; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
Kitajima S; Institute for Advanced Biosciences, Keio University, Tsuruoka, Japan.
Li Z; Department of Paediatrics, National University of Singapore, Singapore.
Eng Juh Yeoh A; Dept of Paediatrics, National University of Singapore and Cancer Science Institute of Singapore.
Hao Tan S; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
Sanda T; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
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Źródło :
Haematologica [Haematologica] 2021 Jun 01; Vol. 106 (6), pp. 1545-1558. Date of Electronic Publication: 2021 Jun 01.
Typ publikacji :
Journal Article
MeSH Terms :
Aldehyde Dehydrogenase*/genetics
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/genetics
Animals ; T-Cell Acute Lymphocytic Leukemia Protein 1 ; T-Lymphocytes ; Transcription Factors ; Zebrafish
Czasopismo naukowe
Tytuł :
Eosinophilia/Hypereosinophilia in the Setting of Reactive and Idiopathic Causes, Well-Defined Myeloid or Lymphoid Leukemias, or Germline Disorders.
Autorzy :
Kelemen K; Division of Hematopathology, Mayo Clinic, Phoenix, AZ.
Saft L; Department of Pathology, Karolinska University Hospital and Institute, Stockholm, Sweden.
Craig FE; Division of Hematopathology, Mayo Clinic, Phoenix, AZ.
Orazi A; Department of Pathology, Texas Tech University Health Sciences Center, El Paso.
Nakashima M; Department of Laboratory Medicine, Cleveland Clinic, Cleveland, OH.
Wertheim GB; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.
George TI; Department of Pathology, University of Utah School of Medicine, Salt Lake City.
Horny HP; Institute of Pathology, University of Munich (LMU), Munich, Germany.
King RL; Division of Hematopathology, Mayo Clinic, Rochester, MN.
Quintanilla-Martinez L; Institute of Pathology and Neuropathology, Eberhard Karls University of Tübingen and Comprehensive Cancer Center, Tübingen University Hospital, Tübingen, Germany.
Wang SA; Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston.
Rimsza LM; Division of Hematopathology, Mayo Clinic, Phoenix, AZ.
Reichard KK; Division of Hematopathology, Mayo Clinic, Rochester, MN.
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Źródło :
American journal of clinical pathology [Am J Clin Pathol] 2021 Feb 04; Vol. 155 (2), pp. 179-210.
Typ publikacji :
Journal Article
MeSH Terms :
Eosinophilia*/diagnosis
Eosinophilia*/etiology
Eosinophilia*/pathology
Hematologic Neoplasms*/diagnosis
Hematologic Neoplasms*/pathology
Hypereosinophilic Syndrome*/diagnosis
Hypereosinophilic Syndrome*/pathology
Leukemia, Lymphoid*/diagnosis
Leukemia, Lymphoid*/pathology
Diagnosis, Differential ; Female ; Fusion Proteins, bcr-abl/metabolism ; Genetic Predisposition to Disease ; Germ Cells/pathology ; Histological Techniques ; Humans ; Leukemia/diagnosis ; Leukemia/pathology ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/diagnosis ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology ; Leukemia, Myeloid, Accelerated Phase/diagnosis ; Leukemia, Myeloid, Accelerated Phase/pathology ; Male ; Myelodysplastic Syndromes/diagnosis ; Myelodysplastic Syndromes/pathology ; Pathology, Molecular ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/diagnosis ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology
SCR Disease Name :
Pdgfra-Associated Chronic Eosinophilic Leukemia
Czasopismo naukowe
Tytuł :
In vivo inducible reverse genetics in patients' tumors to identify individual therapeutic targets.
Autorzy :
Carlet M; Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Munich, Germany.
Völse K; Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Munich, Germany.
Vergalli J; Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Munich, Germany.
Becker M; Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Munich, Germany.
Herold T; Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Munich, Germany.; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK), Partnering Site Munich, Munich, Germany.
Arner A; Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, Ludwig Maximilian University (LMU), Munich, Germany.
Senft D; Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Munich, Germany.
Jurinovic V; Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Munich, Germany.; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, Ludwig Maximilian University (LMU), Munich, Germany.
Liu WH; Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Munich, Germany.
Gao Y; Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Munich, Germany.
Dill V; Clinic and Policlinic for Internal Medicine III, Technical University of Munich, School of Medicine, Munich, Germany.
Fehse B; Research Department Cell and Gene Therapy, Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Baldus CD; Internal Medicine II, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Bastian L; Internal Medicine II, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Lenk L; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
Schewe DM; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
Bagnoli JW; Anthropology and Human Genomics, Faculty of Biology, Ludwig Maximilian University (LMU), Munich, Germany.
Vick B; Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Munich, Germany.; German Cancer Consortium (DKTK), Partnering Site Munich, Munich, Germany.
Schmid JP; Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Munich, Germany.
Wilhelm A; Institute of Pharmaceutical Biology, Diagnosic Center of Acute Leukemias (DCAL), Goethe-University, Frankfurt/Main, Germany.
Marschalek R; Institute of Pharmaceutical Biology, Diagnosic Center of Acute Leukemias (DCAL), Goethe-University, Frankfurt/Main, Germany.
Jost PJ; German Cancer Consortium (DKTK), Partnering Site Munich, Munich, Germany.; Clinic and Policlinic for Internal Medicine III, Technical University of Munich, School of Medicine, Munich, Germany.; Center for Translational Cancer Research (TranslaTUM), Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Miething C; Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany.; German Cancer Consortium (DKTK), Partnering Site Freiburg, Freiburg, Germany.
Riecken K; Research Department Cell and Gene Therapy, Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Schmidt-Supprian M; Institute of Experimental Hematology, Technical University of Munich, Munich, Germany.
Binder V; Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, Ludwig Maximilian University (LMU), Munich, Germany.
Jeremias I; Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Munich, Germany. .; German Cancer Consortium (DKTK), Partnering Site Munich, Munich, Germany. .; Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, Ludwig Maximilian University (LMU), Munich, Germany. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 27; Vol. 12 (1), pp. 5655. Date of Electronic Publication: 2021 Sep 27.
Typ publikacji :
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Biomarkers, Tumor/*genetics
Leukemia, Myeloid, Acute/*drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy
Reverse Genetics/*methods
Adaptor Proteins, Signal Transducing/antagonists & inhibitors ; Adaptor Proteins, Signal Transducing/genetics ; Adult ; Animals ; Antineoplastic Agents/therapeutic use ; Biomarkers, Tumor/antagonists & inhibitors ; Child ; Female ; Gene Silencing ; Homeodomain Proteins/antagonists & inhibitors ; Homeodomain Proteins/genetics ; Humans ; Leukemia, Myeloid, Acute/genetics ; Male ; Mice ; Myeloid Cell Leukemia Sequence 1 Protein/antagonists & inhibitors ; Myeloid Cell Leukemia Sequence 1 Protein/genetics ; Myeloid-Lymphoid Leukemia Protein/antagonists & inhibitors ; Myeloid-Lymphoid Leukemia Protein/genetics ; Oncogene Proteins, Fusion/antagonists & inhibitors ; Oncogene Proteins, Fusion/genetics ; Precision Medicine/methods ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Serial evaluation of the pharmacokinetics of ponatinib in patients with CML and Ph + ALL.
Autorzy :
Kawano N; Department of Internal Medicine, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan. .
Kimura S; Division of Hematology, Department of Internal Medicine, Saga University School of Medicine, Saga, Japan.
Miura M; Division of Pharmacology, Department of Pharmacology, Akita University School of Medicine, Akita, Japan.
Tochigi T; Department of Internal Medicine, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan.
Nakaike T; Department of Internal Medicine, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan.
Yamashita K; Department of Internal Medicine, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan.
Mashiba K; Department of Internal Medicine, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan.
Kikuchi I; Department of Internal Medicine, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan.
Takahashi N; Department of Hematology, Nephrology and Rheumatology, Akita University School of Medicine, Akita, Japan.
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Źródło :
International journal of hematology [Int J Hematol] 2021 Oct; Vol. 114 (4), pp. 509-516. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Imidazoles/*pharmacokinetics
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy
Protein Kinase Inhibitors/*pharmacokinetics
Pyridazines/*pharmacokinetics
Adult ; Aged ; Combined Modality Therapy ; Drug Monitoring ; Female ; Fusion Proteins, bcr-abl/genetics ; Hematopoietic Stem Cell Transplantation ; Humans ; Imidazoles/administration & dosage ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/diagnosis ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/etiology ; Leukemia, Myeloid, Chronic-Phase/diagnosis ; Leukemia, Myeloid, Chronic-Phase/drug therapy ; Male ; Middle Aged ; Molecular Targeted Therapy ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/diagnosis ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/etiology ; Protein Kinase Inhibitors/administration & dosage ; Pyridazines/administration & dosage ; Treatment Outcome
Czasopismo naukowe
Tytuł :
[Role of radiotherapy in haematology].
Autorzy :
Peignaux-Casasnovas K; Département de radiothérapie, centre Georges-François-Leclerc, 1, rue du Professeur-Marion, 21079 Dijon, France. Electronic address: .
Truc G; Département de radiothérapie, centre Georges-François-Leclerc, 1, rue du Professeur-Marion, 21079 Dijon, France.
Rossi C; Service d'hématologie, CHU de François-Mitterrand, 21000 Dijon, France.
Casasnovas O; Service d'hématologie, CHU de François-Mitterrand, 21000 Dijon, France.
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Transliterated Title :
Place de la radiothérapie en hématologie.
Źródło :
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique [Cancer Radiother] 2021 Oct; Vol. 25 (6-7), pp. 603-606. Date of Electronic Publication: 2021 Aug 28.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Leukemia/*radiotherapy
Lymphoma/*radiotherapy
Skin Neoplasms/*radiotherapy
Acute Disease ; Hodgkin Disease/pathology ; Hodgkin Disease/radiotherapy ; Humans ; Leukemia/pathology ; Lymphoma, Non-Hodgkin/pathology ; Lymphoma, Non-Hodgkin/radiotherapy ; Multiple Myeloma/radiotherapy ; Plasmacytoma/radiotherapy ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/radiotherapy ; Sarcoma/radiotherapy ; Skin Neoplasms/pathology
Czasopismo naukowe
Tytuł :
A single assessment of methotrexate levels at 42 hours permits safe administration and early discharge in children with lymphoblastic lymphoma and leukemia receiving high-dose methotrexate.
Autorzy :
Totadri S; Paediatric Haematology/Oncology Unit, Department of Paediatrics, Christian Medical College and Hospital, Vellore, India.
Srinivasan HN; Paediatric Haematology/Oncology Unit, Department of Paediatrics, Christian Medical College and Hospital, Vellore, India.
Joseph LL; Paediatric Haematology/Oncology Unit, Department of Paediatrics, Christian Medical College and Hospital, Vellore, India.
Boddu D; Paediatric Haematology/Oncology Unit, Department of Paediatrics, Christian Medical College and Hospital, Vellore, India.
Mathew LG; Paediatric Haematology/Oncology Unit, Department of Paediatrics, Christian Medical College and Hospital, Vellore, India.
John R; Paediatric Haematology/Oncology Unit, Department of Paediatrics, Christian Medical College and Hospital, Vellore, India.
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Źródło :
Pediatric hematology and oncology [Pediatr Hematol Oncol] 2021 Aug; Vol. 38 (5), pp. 434-443. Date of Electronic Publication: 2021 Mar 25.
Typ publikacji :
Journal Article
MeSH Terms :
Antimetabolites, Antineoplastic/*therapeutic use
Methotrexate/*therapeutic use
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy
Adolescent ; Antimetabolites, Antineoplastic/administration & dosage ; Antimetabolites, Antineoplastic/adverse effects ; Antimetabolites, Antineoplastic/blood ; Child ; Child, Preschool ; Drug Monitoring ; Female ; Humans ; Infant ; Male ; Methotrexate/administration & dosage ; Methotrexate/adverse effects ; Methotrexate/blood ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Retrospective Studies
Czasopismo naukowe
Tytuł :
High-throughput sequencing of immunoglobulin heavy chain for minimal residual disease detection in B-lymphoblastic leukemia.
Autorzy :
Correia RP; Departments of Clinical Pathology Laboratory, Hematology and Hemotherapy, Research Institute, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Puga RD; Departments of Clinical Pathology Laboratory, Hematology and Hemotherapy, Research Institute, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Muto NH; Departments of Clinical Pathology Laboratory, Hematology and Hemotherapy, Research Institute, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Lee MLM; Grupo de Apoio ao Adolescente e a Criança com Câncer, São Paulo, Brazil.
Torres DC; Bone Marrow Transplantation Center, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.
Hassan R; Bone Marrow Transplantation Center, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.
Bacal NS; Departments of Clinical Pathology Laboratory, Hematology and Hemotherapy, Research Institute, Hospital Israelita Albert Einstein, São Paulo, Brazil.; Centro de Hematologia de São Paulo, São Paulo, Brazil.
Hamerschlak N; Departments of Clinical Pathology Laboratory, Hematology and Hemotherapy, Research Institute, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Campregher PV; Departments of Clinical Pathology Laboratory, Hematology and Hemotherapy, Research Institute, Hospital Israelita Albert Einstein, São Paulo, Brazil.
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Źródło :
International journal of laboratory hematology [Int J Lab Hematol] 2021 Aug; Vol. 43 (4), pp. 724-731. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :
Journal Article
MeSH Terms :
Immunoglobulin Heavy Chains/*genetics
Neoplasm, Residual/*genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
High-Throughput Nucleotide Sequencing ; Humans ; Neoplasm, Residual/diagnosis ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/diagnosis ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/diagnosis
Czasopismo naukowe
Tytuł :
Very Late Relapse in Pediatric Acute Myeloid Leukemia: A Case Report and Brief Literature Review.
Autorzy :
Unis GD; Ochsner Hospital for Children, New Orleans, LA.
VanderVeen N; Ronald Reagan UCLA Medical Center, Los Angeles, CA.
Fletcher M; Ochsner Hospital for Children, New Orleans, LA.
Vasquez RJ; Ochsner Hospital for Children, New Orleans, LA.
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Źródło :
Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2021 Aug 01; Vol. 43 (6), pp. 236-239.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
Leukemia, Myeloid, Acute/*therapy
Adult ; Child ; Hematopoietic Stem Cell Transplantation ; Histone-Lysine N-Methyltransferase/genetics ; Humans ; Kinesin/genetics ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/genetics ; Myeloid-Lymphoid Leukemia Protein/genetics ; Myosins/genetics ; Neoplasm Recurrence, Local/diagnosis ; Neoplasm Recurrence, Local/genetics ; Translocation, Genetic
Czasopismo naukowe
Tytuł :
Treatment advances for pediatric and adult onset neoplasms with monocytosis.
Autorzy :
McCullough KB; Department of Pharmacy Services, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA. .
Kuhn AK; Department of Pharmacy Services, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA.
Patnaik MM; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
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Źródło :
Current hematologic malignancy reports [Curr Hematol Malig Rep] 2021 Jun; Vol. 16 (3), pp. 256-266. Date of Electronic Publication: 2021 Mar 16.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Leukemia, Myeloid/*therapy
Leukemia, Myelomonocytic, Juvenile/*therapy
Age Factors ; Biomarkers ; Combined Modality Therapy ; Disease Management ; Disease Susceptibility ; Hematopoietic Stem Cell Transplantation ; Humans ; Leukemia, Myeloid/diagnosis ; Leukemia, Myeloid/etiology ; Leukemia, Myelomonocytic, Chronic/diagnosis ; Leukemia, Myelomonocytic, Chronic/etiology ; Leukemia, Myelomonocytic, Chronic/therapy ; Leukemia, Myelomonocytic, Juvenile/diagnosis ; Leukemia, Myelomonocytic, Juvenile/etiology ; Molecular Targeted Therapy
Czasopismo naukowe
Tytuł :
Prevalence of feline leukaemia provirus DNA in feline lymphomas.
Autorzy :
Moll GM
Swenson CL
Yuzbasiyan-Gurkan V
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Źródło :
Journal of feline medicine and surgery [J Feline Med Surg] 2021 Feb; Vol. 23 (2), pp. 203-204. Date of Electronic Publication: 2020 Dec 08.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Cat Diseases*/epidemiology
Leukemia, Feline*
Lymphoma*/epidemiology
Lymphoma*/veterinary
Animals ; Cats ; DNA, Viral ; Leukemia Virus, Feline ; Prevalence ; Proviruses/genetics
Raport
Tytuł :
Remarkable stability in clonal hematopoiesis involving leukemia-driver genes in patients without underlying myeloid neoplasms.
Autorzy :
Kusne Y; Department of Internal Medicine, Mayo Clinic, Scottsdale, Arizona, USA.
Lasho T; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Mangaonkar A; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Tefferi A; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Gangat N; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Finke C; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Binder M; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Chia N; Department of Surgery and Pharmacology, Mayo Clinic, Rochester, Minnesota, USA.
Patnaik MM; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
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Źródło :
American journal of hematology [Am J Hematol] 2021 Oct 01; Vol. 96 (10), pp. E392-E396. Date of Electronic Publication: 2021 Aug 02.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Clonal Hematopoiesis*
Gene Expression Regulation, Leukemic*
Leukemia/*genetics
Aged ; Aged, 80 and over ; DNA (Cytosine-5-)-Methyltransferases/genetics ; Female ; Humans ; Leukemia, Myeloid/genetics ; Male ; Middle Aged ; Mutation
Raport

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