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Tytuł :
A Randomized Trial of Comparing a Combination of Montelukast and Budesonide With Budesonide in Allergic Rhinitis.
Autorzy :
Chen H; Department of Otolaryngology-Head and Neck Surgery.; and Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing, China.; Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.; Department of Otolaryngology, Wangjing Hospital, China Academy of Chinese Medical Science, Beijing, China.
Zhang L; Department of Otolaryngology-Head and Neck Surgery.; and Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing, China.; Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.
Lou H; Department of Otolaryngology-Head and Neck Surgery.; Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.
Wang Y
Cao F; and Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing, China.; Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.
Wang C; Department of Otolaryngology-Head and Neck Surgery.; and Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing, China.; Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.
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Źródło :
The Laryngoscope [Laryngoscope] 2021 Apr; Vol. 131 (4), pp. E1054-E1061. Date of Electronic Publication: 2019 Nov 29.
Typ publikacji :
Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetates/*therapeutic use
Bronchodilator Agents/*therapeutic use
Budesonide/*therapeutic use
Cyclopropanes/*therapeutic use
Leukotriene Antagonists/*therapeutic use
Quinolines/*therapeutic use
Rhinitis, Allergic/*drug therapy
Sulfides/*therapeutic use
Acetates/administration & dosage ; Administration, Intranasal ; Adult ; Bronchodilator Agents/administration & dosage ; Budesonide/administration & dosage ; China ; Cyclopropanes/administration & dosage ; Drug Therapy, Combination ; Female ; Humans ; Leukotriene Antagonists/administration & dosage ; Male ; Nasal Obstruction/drug therapy ; Quinolines/administration & dosage ; Sulfides/administration & dosage
Czasopismo naukowe
Tytuł :
Leukotriene receptor antagonist addition to intranasal steroid: systematic review and meta-analysis.
Autorzy :
Seresirikachorn K; Department of Otolaryngology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; Endoscopic Nasal and Sinus Surgery Excellence Center, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Mullol J; Rhinology Unit & Smell Clinic, ENT Department, Hospital Clinic, IDIBAPS, Universitat de Barcelona, CIBERES, Barcelona, Catalonia, Spain.
Limitlaohaphan K; Relief and Community Health Bureau, The Thai Red cross Societies, Bangkok, Thailand.
Asvapoositkul V; Bangkok Metropolitan Administration General Hospital. Bangkok, Thailand.
Snidvongs K; Department of Otolaryngology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; Endoscopic Nasal and Sinus Surgery Excellence Center, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
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Źródło :
Rhinology [Rhinology] 2021 Feb 01; Vol. 59 (1), pp. 2-9.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Leukotriene Antagonists*/therapeutic use
Rhinitis, Allergic*/drug therapy
Administration, Intranasal ; Adrenal Cortex Hormones/therapeutic use ; Humans ; Quality of Life ; Steroids
Czasopismo naukowe
Tytuł :
Pharmacotherapeutic management of asthma in the elderly patient.
Autorzy :
Albertson TE; Department of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, School of Medicine, U. C. Davis , Sacramento, CA, USA.; Department of Emergency Medicine, School of Medicine, U. C. Davis , Sacramento, CA, USA.; Department of Medicine, Veterans Administration Northern California Health Care System , Mather, CA, USA.
Pugashetti JV; Department of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, School of Medicine, U. C. Davis , Sacramento, CA, USA.; Department of Medicine, Veterans Administration Northern California Health Care System , Mather, CA, USA.
Chau-Etchepare F; Department of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, School of Medicine, U. C. Davis , Sacramento, CA, USA.; Department of Medicine, Veterans Administration Northern California Health Care System , Mather, CA, USA.
Chenoweth JA; Department of Emergency Medicine, School of Medicine, U. C. Davis , Sacramento, CA, USA.; Department of Medicine, Veterans Administration Northern California Health Care System , Mather, CA, USA.
Murin S; Department of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, School of Medicine, U. C. Davis , Sacramento, CA, USA.; Department of Medicine, Veterans Administration Northern California Health Care System , Mather, CA, USA.
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Źródło :
Expert opinion on pharmacotherapy [Expert Opin Pharmacother] 2020 Nov; Vol. 21 (16), pp. 1991-2010. Date of Electronic Publication: 2020 Jul 20.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Adrenal Cortex Hormones/*therapeutic use
Anti-Inflammatory Agents/*therapeutic use
Asthma/*drug therapy
Bronchodilator Agents/*therapeutic use
Leukotriene Antagonists/*therapeutic use
Muscarinic Antagonists/*therapeutic use
Administration, Inhalation ; Adrenal Cortex Hormones/administration & dosage ; Adult ; Aged ; Anti-Inflammatory Agents/administration & dosage ; Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome/drug therapy ; Humans ; Leukotriene Antagonists/administration & dosage ; Macrolides/administration & dosage ; Macrolides/therapeutic use ; Medication Adherence ; Metered Dose Inhalers ; Muscarinic Antagonists/administration & dosage ; Smoking/adverse effects
Czasopismo naukowe
Tytuł :
The efficacy of a leukotriene receptor antagonist in the treatment of human rectal aberrant crypt foci: a nonrandomized, open-label, controlled trial.
Autorzy :
Higurashi T; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa, Yokohama, Kanagawa, 236-0004, Japan. .
Arimoto J; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa, Yokohama, Kanagawa, 236-0004, Japan.
Ashikari K; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa, Yokohama, Kanagawa, 236-0004, Japan.
Takatsu T; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa, Yokohama, Kanagawa, 236-0004, Japan.
Misawa N; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa, Yokohama, Kanagawa, 236-0004, Japan.
Yoshihara T; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa, Yokohama, Kanagawa, 236-0004, Japan.
Matsuura T; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa, Yokohama, Kanagawa, 236-0004, Japan.
Fuyuki A; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa, Yokohama, Kanagawa, 236-0004, Japan.
Ohkubo H; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa, Yokohama, Kanagawa, 236-0004, Japan.
Nakajima A; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa, Yokohama, Kanagawa, 236-0004, Japan.
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Źródło :
BMC cancer [BMC Cancer] 2020 Aug 17; Vol. 20 (1), pp. 770. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji :
Clinical Trial Protocol; Journal Article
MeSH Terms :
Aberrant Crypt Foci/*prevention & control
Acetates/*administration & dosage
Colonic Polyps/*therapy
Cyclopropanes/*administration & dosage
Intestinal Mucosa/*drug effects
Leukotriene Antagonists/*administration & dosage
Quinolines/*administration & dosage
Sulfides/*administration & dosage
Aberrant Crypt Foci/diagnosis ; Aberrant Crypt Foci/pathology ; Aberrant Crypt Foci/surgery ; Acetates/adverse effects ; Administration, Oral ; Adult ; Aged ; Aged, 80 and over ; Biopsy ; Cell Proliferation/drug effects ; Colon/diagnostic imaging ; Colon/drug effects ; Colon/pathology ; Colon/surgery ; Colonic Polyps/pathology ; Colonoscopy ; Controlled Clinical Trials as Topic ; Cyclopropanes/adverse effects ; Female ; Humans ; Intestinal Mucosa/diagnostic imaging ; Intestinal Mucosa/pathology ; Intestinal Mucosa/surgery ; Leukotriene Antagonists/adverse effects ; Male ; Middle Aged ; Pilot Projects ; Prospective Studies ; Quinolines/adverse effects ; Rectum/diagnostic imaging ; Rectum/drug effects ; Rectum/pathology ; Rectum/surgery ; Sulfides/adverse effects ; Treatment Outcome
Czasopismo naukowe
Tytuł :
The potential role of peak nasal inspiratory flow to evaluate active sinonasal inflammation and disease severity.
Autorzy :
Araújo-Martins J; Otolaryngology, Hospital de Torres Vedras, Centro Hospitalar do Oeste - Torres Vedras, Rua Dr. Aurélio Ricardo Belo, 2560-364, Torres Vedras, Portugal. .; Environmental Health Research Group, CHRC/CEDOC, NOVA Medical School, Lisboa, Portugal. .
Brás-Geraldes C; Centro de Estatística e Aplicações, Universidade de Lisboa, Lisboa, Portugal.; ADM - Instituto Superior de Engenharia de Lisboa, Lisboa, Portugal.
Neuparth N; Environmental Health Research Group, CHRC/CEDOC, NOVA Medical School, Lisboa, Portugal.
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Źródło :
Scientific reports [Sci Rep] 2020 Jul 29; Vol. 10 (1), pp. 12674. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adrenal Cortex Hormones/*administration & dosage
Clarithromycin/*administration & dosage
Leukotriene Antagonists/*administration & dosage
Nasal Obstruction/*diagnosis
Nasal Polyps/*pathology
Rhinomanometry/*methods
Sinusitis/*pathology
Administration, Intranasal ; Administration, Topical ; Adrenal Cortex Hormones/therapeutic use ; Adult ; Aged ; Case-Control Studies ; Clarithromycin/therapeutic use ; Cross-Sectional Studies ; Female ; Humans ; Leukotriene Antagonists/therapeutic use ; Male ; Middle Aged ; Nasal Obstruction/drug therapy ; Nasal Polyps/drug therapy ; Prospective Studies ; Reproducibility of Results ; Rhinomanometry/instrumentation ; Severity of Illness Index ; Sinusitis/drug therapy ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Comparison table: Some oral drugs for allergic rhinitis.
Źródło :
The Medical letter on drugs and therapeutics [Med Lett Drugs Ther] 2021 Apr 19; Vol. 63 (1622), pp. e63-e65. Date of Electronic Publication: 2021 Apr 19.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Anti-Allergic Agents/*administration & dosage
Rhinitis, Allergic/*drug therapy
Administration, Oral ; Anti-Allergic Agents/pharmacology ; Histamine H1 Antagonists, Non-Sedating/administration & dosage ; Humans ; Leukotriene Antagonists/administration & dosage
Czasopismo naukowe
Tytuł :
Adverse events associated with weight-based, high-dose montelukast exposures in children.
Autorzy :
Arnold DH; Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA.; Department of Emergency Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.; Center for Asthma Research, Vanderbilt University School of Medicine, Nashville, TN, USA.
Bowman N; Tennessee Poison Center, Nashville, TN, USA.
Reiss TF; Celgene Corporation, Summit, NJ, USA.
Hartert TV; Center for Asthma Research, Vanderbilt University School of Medicine, Nashville, TN, USA.; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.
Akers WS; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pharmaceutical Sciences, Lipscomb University College of Pharmacy, Nashville, TN, USA.
Seger DL; Department of Emergency Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.; Tennessee Poison Center, Nashville, TN, USA.; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.
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Źródło :
Clinical toxicology (Philadelphia, Pa.) [Clin Toxicol (Phila)] 2020 Feb; Vol. 58 (2), pp. 145-146. Date of Electronic Publication: 2019 May 06.
Typ publikacji :
Letter
MeSH Terms :
Acetates/*administration & dosage
Acetates/*adverse effects
Asthma/*drug therapy
Leukotriene Antagonists/*administration & dosage
Leukotriene Antagonists/*adverse effects
Quinolines/*administration & dosage
Quinolines/*adverse effects
Acetates/therapeutic use ; Body Weight ; Child ; Dose-Response Relationship, Drug ; Drug Dosage Calculations ; Female ; Humans ; Leukotriene Antagonists/therapeutic use ; Male ; Poison Control Centers ; Quinolines/therapeutic use
Opinia redakcyjna
Tytuł :
Prescription Status and Clinical Outcomes of Methylxanthines and Leukotriene Receptor Antagonists in Mild-to-Moderate Chronic Obstructive Pulmonary Disease.
Autorzy :
Lee JK; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea.
Rhee CK; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, the Catholic University of Korea, Seoul, Republic of Korea.
Kim K; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, the Catholic University of Korea, Seoul, Republic of Korea.
Ra SW; Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea.
Lee JH; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea.
Jung KS; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Republic of Korea.
Yoo KH; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Republic of Korea.
Kim YI; Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Kim DK; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea.
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Źródło :
International journal of chronic obstructive pulmonary disease [Int J Chron Obstruct Pulmon Dis] 2019 Nov 27; Vol. 14, pp. 2639-2647. Date of Electronic Publication: 2019 Nov 27 (Print Publication: 2019).
Typ publikacji :
Journal Article
MeSH Terms :
Bronchodilator Agents/*therapeutic use
Leukotriene Antagonists/*therapeutic use
Lung/*drug effects
Practice Patterns, Physicians'/*trends
Pulmonary Disease, Chronic Obstructive/*drug therapy
Xanthines/*therapeutic use
Aged ; Bronchodilator Agents/adverse effects ; Bronchodilator Agents/economics ; Disease Progression ; Drug Costs ; Drug Prescriptions ; Drug Utilization/trends ; Female ; Forced Expiratory Volume ; Hospital Costs ; Hospitalization ; Humans ; Leukotriene Antagonists/adverse effects ; Leukotriene Antagonists/economics ; Lung/physiopathology ; Male ; Middle Aged ; Nutrition Surveys ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/economics ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Republic of Korea ; Retrospective Studies ; Severity of Illness Index ; Time Factors ; Treatment Outcome ; Xanthines/adverse effects ; Xanthines/economics
Czasopismo naukowe
Tytuł :
Phase 2 trial of montelukast for prevention of pain in sickle cell disease.
Autorzy :
Field JJ; Medical Sciences Institute, Versiti Wisconsin, Milwaukee, WI.; Department of Medicine, Medical College of Wisconsin, Milwaukee, WI.
Kassim A; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.
Brandow A; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.
Embury SH; Vanguard Therapeutics, Inc., Half Moon Bay, CA; and.
Matsui N; Vanguard Therapeutics, Inc., Half Moon Bay, CA; and.
Wilkerson K; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.
Bryant V; Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN.
Zhang L; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.
Simpson P; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.
DeBaun MR; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.; Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN.
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Źródło :
Blood advances [Blood Adv] 2020 Mar 24; Vol. 4 (6), pp. 1159-1165.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Anemia, Sickle Cell*/complications
Anemia, Sickle Cell*/drug therapy
Leukotriene Antagonists*/therapeutic use
Acetates/therapeutic use ; Adolescent ; Adult ; Cyclopropanes ; Humans ; Pain/drug therapy ; Pain/etiology ; Pain/prevention & control ; Quinolines ; Sulfides
Czasopismo naukowe
Tytuł :
The leukotriene receptor antagonist Montelukast can induce adverse skin reactions in asthmatic patients.
Autorzy :
Di Salvo E; National Research Council of Italy (CNR), Institute of Applied Science and Intelligent System (ISASI), Messina Unit, Messina, Italy. Electronic address: .
Patella V; Division Allergy and Clinical Immunology, Department of Medicine ASL Salerno, 'Santa Maria della Speranza' Hospital, Salerno, Italy. Electronic address: .
Casciaro M; School and Unit of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy. Electronic address: .
Gangemi S; School and Unit of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy. Electronic address: .
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Źródło :
Pulmonary pharmacology & therapeutics [Pulm Pharmacol Ther] 2020 Feb; Vol. 60, pp. 101875. Date of Electronic Publication: 2019 Dec 11.
Typ publikacji :
Journal Article; Review; Systematic Review
MeSH Terms :
Acetates/*adverse effects
Anti-Asthmatic Agents/*adverse effects
Cyclopropanes/*adverse effects
Leukotriene Antagonists/*adverse effects
Quinolines/*adverse effects
Sulfides/*adverse effects
Acetates/therapeutic use ; Adult ; Aged ; Anti-Asthmatic Agents/therapeutic use ; Cyclopropanes/therapeutic use ; Female ; Humans ; Leukotriene Antagonists/therapeutic use ; Male ; Middle Aged ; Quinolines/therapeutic use ; Skin/drug effects ; Sulfides/therapeutic use
Czasopismo naukowe
Tytuł :
The Leukotriene Receptor Antagonist Montelukast Attenuates Neuroinflammation and Affects Cognition in Transgenic 5xFAD Mice.
Autorzy :
Michael J; Institute of Molecular Regenerative Medicine, Paracelsus Medical University, 5020 Salzburg, Austria.; Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI-TReCS), Paracelsus Medical University, 5020 Salzburg, Austria.
Zirknitzer J; Institute of Molecular Regenerative Medicine, Paracelsus Medical University, 5020 Salzburg, Austria.; Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI-TReCS), Paracelsus Medical University, 5020 Salzburg, Austria.
Unger MS; Institute of Molecular Regenerative Medicine, Paracelsus Medical University, 5020 Salzburg, Austria.; Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI-TReCS), Paracelsus Medical University, 5020 Salzburg, Austria.
Poupardin R; Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI-TReCS), Paracelsus Medical University, 5020 Salzburg, Austria.
Rieß T; Institute of Molecular Regenerative Medicine, Paracelsus Medical University, 5020 Salzburg, Austria.; Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI-TReCS), Paracelsus Medical University, 5020 Salzburg, Austria.
Paiement N; IntelgenX Corp., Saint-Laurent, QC H4S 1Y2, Canada.
Zerbe H; IntelgenX Corp., Saint-Laurent, QC H4S 1Y2, Canada.
Hutter-Paier B; QPS Neuropharmacology, 8074 Grambach/Graz, Austria.
Reitsamer H; Research Program for Experimental Ophthalmology, Department of Ophthalmology and Optometry, University Hospital of the Paracelsus Medical University, 5020 Salzburg, Austria.
Aigner L; Institute of Molecular Regenerative Medicine, Paracelsus Medical University, 5020 Salzburg, Austria.; Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI-TReCS), Paracelsus Medical University, 5020 Salzburg, Austria.; Austrian Cluster of Tissue Regeneration, 1200 Vienna, Austria.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 09; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 09.
Typ publikacji :
Journal Article
MeSH Terms :
Acetates/*pharmacology
Alzheimer Disease/*drug therapy
Brain/*metabolism
CD8-Positive T-Lymphocytes/*metabolism
Cognition/*drug effects
Cyclopropanes/*pharmacology
Leukotriene Antagonists/*pharmacology
Quinolines/*pharmacology
Sulfides/*pharmacology
Alzheimer Disease/genetics ; Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Animals ; Brain/pathology ; CD8-Positive T-Lymphocytes/pathology ; Inflammation/drug therapy ; Inflammation/metabolism ; Inflammation/pathology ; Mice ; Mice, Transgenic
Czasopismo naukowe
Tytuł :
Leukotriene receptor antagonists enhance HCC treatment efficacy by inhibiting ADAMs and suppressing MICA shedding.
Autorzy :
Arai J; Division of Advanced Genome Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan. .; Division of Gastroenterology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan. .
Goto K; Division of Advanced Genome Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Otoyama Y; Division of Gastroenterology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan.
Nakajima Y; Division of Gastroenterology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan.
Sugiura I; Division of Gastroenterology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan.
Kajiwara A; Division of Gastroenterology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan.
Tojo M; Division of Gastroenterology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan.
Ichikawa Y; Division of Gastroenterology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan.
Uozumi S; Division of Gastroenterology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan.
Shimozuma Y; Division of Gastroenterology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan.
Uchikoshi M; Division of Gastroenterology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan.
Sakaki M; Division of Gastroenterology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan.
Nozawa H; Division of Gastroenterology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan.
Nakagawa R; Division of Advanced Genome Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Muroyama R; Division of Advanced Genome Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Kato N; Division of Advanced Genome Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Yoshida H; Division of Gastroenterology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan.
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2021 Jan; Vol. 70 (1), pp. 203-213. Date of Electronic Publication: 2020 Jul 18.
Typ publikacji :
Journal Article
MeSH Terms :
ADAM Proteins/*metabolism
Carcinoma, Hepatocellular/*drug therapy
Histocompatibility Antigens Class I/*metabolism
Leukotriene Antagonists/*pharmacology
Liver Neoplasms/*drug therapy
Carcinoma, Hepatocellular/metabolism ; Cell Line, Tumor ; Down-Regulation/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Genome-Wide Association Study/methods ; Hep G2 Cells ; Humans ; Killer Cells, Natural/drug effects ; Killer Cells, Natural/metabolism ; Liver Neoplasms/metabolism ; Membrane Proteins/metabolism ; Phenylurea Compounds/pharmacology ; Pyridines/pharmacology ; Treatment Outcome ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Antiviral activity against Middle East Respiratory Syndrome coronavirus by Montelukast, an anti-asthma drug.
Autorzy :
Gan HJ; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore.
Harikishore A; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore.
Lee J; Zoonotic Virus Laboratory, Institut Pasteur Korea, Seongnam, South Korea.
Jeon S; Zoonotic Virus Laboratory, Institut Pasteur Korea, Seongnam, South Korea.
Rajan S; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore.
Chen MW; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore.
Neo JL; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore.
Kim S; Zoonotic Virus Laboratory, Institut Pasteur Korea, Seongnam, South Korea. Electronic address: .
Yoon HS; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore. Electronic address: .
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Źródło :
Antiviral research [Antiviral Res] 2021 Jan; Vol. 185, pp. 104996. Date of Electronic Publication: 2020 Dec 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetates/*pharmacology
Antiviral Agents/*pharmacology
Cyclopropanes/*pharmacology
Middle East Respiratory Syndrome Coronavirus/*drug effects
Quinolines/*pharmacology
Sulfides/*pharmacology
Animals ; Anti-Asthmatic Agents/pharmacology ; Carrier Proteins/drug effects ; Chlorocebus aethiops ; Coronavirus Infections/drug therapy ; Cytochrome P-450 CYP1A2 Inducers/pharmacology ; Dipeptidyl Peptidase 4/genetics ; Dipeptidyl Peptidase 4/metabolism ; Drug Repositioning ; HEK293 Cells ; Humans ; Leukotriene Antagonists/pharmacology ; Receptors, Virus/genetics ; Receptors, Virus/metabolism ; Spike Glycoprotein, Coronavirus/metabolism ; Vero Cells ; Virus Internalization/drug effects
Czasopismo naukowe
Tytuł :
Developmental Pharmacogenetics of SLCO2B1 on Montelukast Pharmacokinetics in Chinese Children.
Autorzy :
Li Q; Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Shandong University, Jinan, People's Republic of China.; Department of Pharmacy, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Jinan, People's Republic of China.
Wang K; Department of Respiratory Disease, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Jinan, People's Republic of China.
Shi HY; Department of Pharmacy, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Jinan, People's Republic of China.
Wu YE; Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Shandong University, Jinan, People's Republic of China.
Zhou Y; Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Shandong University, Jinan, People's Republic of China.
Kan M; Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Shandong University, Jinan, People's Republic of China.
Zheng Y; Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Shandong University, Jinan, People's Republic of China.
Hao GX; Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Shandong University, Jinan, People's Republic of China.
Yang XM; Department of Pharmacy, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Jinan, People's Republic of China.
Yang YL; Department of Pharmacy, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Jinan, People's Republic of China.
Su LQ; Department of Pharmacy, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Jinan, People's Republic of China.
Wang XL; Clinical Research Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, People's Republic of China.
Jacqz-Aigrain E; Department of Pediatric Pharmacology and Pharmacogenetics, Hôpital Robert Debré, AP-HP, Paris, France.; University Paris Diderot, Sorbonne Paris-Cité, Paris, France.
Zhou J; Clinical Training Center, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Jinan, People's Republic of China.
Zhao W; Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Shandong University, Jinan, People's Republic of China.; Department of Pharmacy, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Jinan, People's Republic of China.
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Źródło :
Drug design, development and therapy [Drug Des Devel Ther] 2019 Dec 27; Vol. 13, pp. 4405-4411. Date of Electronic Publication: 2019 Dec 27 (Print Publication: 2019).
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Acetates/*pharmacokinetics
Asthma/*drug therapy
Leukotriene Antagonists/*pharmacokinetics
Organic Anion Transporters/*antagonists & inhibitors
Quinolines/*pharmacokinetics
Receptors, Leukotriene/*metabolism
Acetates/blood ; Asthma/metabolism ; Child ; Child, Preschool ; China ; Female ; Genotype ; Humans ; Infant ; Leukotriene Antagonists/blood ; Male ; Organic Anion Transporters/genetics ; Organic Anion Transporters/metabolism ; Pharmacogenetics ; Prospective Studies ; Quinolines/blood
Czasopismo naukowe
Tytuł :
Montelukast Prevents Early Diabetic Retinopathy in Mice.
Autorzy :
Bapputty R; Department of Pediatrics, School of Medicine, Case Western Reserve University, University Hospitals Rainbow Babies & Children's Hospital, Cleveland, OH.
Talahalli R; Department of Pediatrics, School of Medicine, Case Western Reserve University, University Hospitals Rainbow Babies & Children's Hospital, Cleveland, OH.
Zarini S; Department of Pharmacology, University of Colorado, Aurora, CO.
Samuels I; Research Service, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH.
Murphy R; Department of Pharmacology, University of Colorado, Aurora, CO.
Gubitosi-Klug R; Department of Pediatrics, School of Medicine, Case Western Reserve University, University Hospitals Rainbow Babies & Children's Hospital, Cleveland, OH .
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Źródło :
Diabetes [Diabetes] 2019 Oct; Vol. 68 (10), pp. 2004-2015. Date of Electronic Publication: 2019 Jul 26.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Acetates/*therapeutic use
Diabetes Mellitus, Experimental/*complications
Diabetic Retinopathy/*prevention & control
Leukotriene Antagonists/*therapeutic use
Quinolines/*therapeutic use
Retina/*drug effects
Acetates/administration & dosage ; Animals ; Capillary Permeability/drug effects ; Diabetes Mellitus, Experimental/metabolism ; Diabetic Retinopathy/metabolism ; Electroretinography ; Inflammation/metabolism ; Leukotriene Antagonists/administration & dosage ; Male ; Mice ; Quinolines/administration & dosage ; Retina/metabolism ; Retinal Vessels/drug effects ; Retinal Vessels/metabolism ; Superoxides/metabolism ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Leukotriene Receptor Antagonist Addition to H1-Antihistamine Is Effective for Treating Allergic Rhinitis: A Systematic Review and Meta-analysis.
Autorzy :
Seresirikachorn K; 1 Department of Otolaryngology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.; 2 Endoscopic Nasal and Sinus Surgery Excellence Center, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Chitsuthipakorn W; 3 Department of Otolaryngology, Rajavithi Hospital, Bangkok, Thailand.
Kanjanawasee D; 1 Department of Otolaryngology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.; 2 Endoscopic Nasal and Sinus Surgery Excellence Center, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Khattiyawittayakun L; 1 Department of Otolaryngology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.; 4 Department of Otolaryngology, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima, Thailand.
Snidvongs K; 1 Department of Otolaryngology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.; 2 Endoscopic Nasal and Sinus Surgery Excellence Center, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
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Źródło :
American journal of rhinology & allergy [Am J Rhinol Allergy] 2019 Sep; Vol. 33 (5), pp. 591-600. Date of Electronic Publication: 2019 Apr 22.
Typ publikacji :
Comparative Study; Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Anti-Allergic Agents/*therapeutic use
Anti-Asthmatic Agents/*therapeutic use
Histamine H1 Antagonists/*therapeutic use
Leukotriene Antagonists/*therapeutic use
Rhinitis, Allergic/*drug therapy
Adult ; Anti-Allergic Agents/adverse effects ; Anti-Asthmatic Agents/adverse effects ; Conjunctivitis/pathology ; Conjunctivitis/prevention & control ; Drug Therapy, Combination ; Female ; Histamine H1 Antagonists/adverse effects ; Humans ; Leukotriene Antagonists/adverse effects ; Male ; Randomized Controlled Trials as Topic ; Rhinitis, Allergic/pathology ; Treatment Outcome
Czasopismo naukowe
Tytuł :
A case report on concurrent occurrence of systemic mastocytosis and myeloid sarcoma presenting with extensive skin involvements and the results of genetic study.
Autorzy :
Wang X; Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Zhang L
Zhou D
Cai H
Wang X
Jiang X
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Dec 11; Vol. 99 (50), pp. e21948.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Mastocytosis, Systemic/*complications
Proto-Oncogene Proteins c-kit/*genetics
Sarcoma, Myeloid/*complications
Skin/*pathology
Adult ; Antibiotics, Antineoplastic ; Antimetabolites, Antineoplastic/therapeutic use ; CD2 Antigens/metabolism ; Cytarabine/therapeutic use ; DNA-Binding Proteins/genetics ; Dasatinib/therapeutic use ; Daunorubicin/therapeutic use ; Drug Therapy, Combination ; Histamine Antagonists/therapeutic use ; Humans ; Interleukin-2 Receptor alpha Subunit/metabolism ; Leukotriene Antagonists/therapeutic use ; Lymph Nodes/metabolism ; Lymph Nodes/pathology ; Male ; Mastocytosis, Systemic/drug therapy ; Mastocytosis, Systemic/genetics ; Mastocytosis, Systemic/pathology ; Mutation ; Platelet Transfusion/methods ; Protein Kinase Inhibitors/therapeutic use ; Sarcoma, Myeloid/drug therapy ; Sarcoma, Myeloid/genetics ; Sarcoma, Myeloid/pathology ; Transcription Factors/genetics ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Airway mechanics after withdrawal of a leukotriene receptor antagonist in children with mild persistent asthma: Double-blind, randomized, cross-over study.
Autorzy :
Kim JH; Departments of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Republic of Korea.
Lee S; Departments of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Republic of Korea.
Shin YH; Department of Pediatrics, CHA Gangnam Medical Center, CHA University School of Medicine, Seoul, Republic of Korea.
Ha EK; Department of Pediatrics, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea.
Lee SW; Department of Data Science, Sejong University College of Software Convergence, Seoul, Republic of Korea.
Kim MA; Departments of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Republic of Korea.
Yoon JW; Department of Pediatrics, Myongji Hospital, Seonam University College of Medicine, Goyang, Republic of Korea.
Baek HS; Department of Pediatrics, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea.
Choi SH; Department of Pediatrics, Kyung Hee University School of Medicine, Seoul, Republic of Korea.
Han MY; Departments of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Republic of Korea.
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Źródło :
Pediatric pulmonology [Pediatr Pulmonol] 2020 Dec; Vol. 55 (12), pp. 3279-3286. Date of Electronic Publication: 2020 Sep 29.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetates/*administration & dosage
Anti-Asthmatic Agents/*administration & dosage
Asthma/*drug therapy
Cyclopropanes/*administration & dosage
Leukotriene Antagonists/*administration & dosage
Quinolines/*administration & dosage
Sulfides/*administration & dosage
Administration, Inhalation ; Albuterol/administration & dosage ; Asthma/metabolism ; Asthma/physiopathology ; Bronchodilator Agents/administration & dosage ; Child ; Cross-Over Studies ; Double-Blind Method ; Female ; Humans ; Male ; Nitric Oxide/metabolism ; Spirometry ; Withholding Treatment
Czasopismo naukowe
Tytuł :
Taming the cytokine storm: repurposing montelukast for the attenuation and prophylaxis of severe COVID-19 symptoms.
Autorzy :
Sanghai N; College of Pharmacy, Rady Faculty of Health Science, University of Manitoba, Winnipeg, MB, R3E 0T5, Canada.
Tranmer GK; College of Pharmacy, Rady Faculty of Health Science, University of Manitoba, Winnipeg, MB, R3E 0T5, Canada. Electronic address: .
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Źródło :
Drug discovery today [Drug Discov Today] 2020 Dec; Vol. 25 (12), pp. 2076-2079. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetates/*therapeutic use
COVID-19/*drug therapy
Cytokine Release Syndrome/*drug therapy
Cytokines/*immunology
Leukotriene Antagonists/*therapeutic use
NF-kappa B/*immunology
Quinolines/*therapeutic use
Respiratory Distress Syndrome/*therapy
Age Factors ; COVID-19/immunology ; Cytokine Release Syndrome/immunology ; Drug Repositioning ; Humans ; Obesity/immunology ; Respiratory Distress Syndrome/immunology ; Severity of Illness Index ; Sex Factors ; Signal Transduction/immunology
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe

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